X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=help%2Fhelp%2Fhtml%2Ffeatures%2Fimportvcf.html;h=7b699eb3462c3d104eaf623410f76caa1f0805d7;hb=cfcd397b19f70fb39d6d21437db8eb6ffcac3914;hp=511ff2e5e2e0683ced84c75cce2b42f08e4cd1ca;hpb=076ec2ac8a7b1488476454c36b6a23255bed1529;p=jalview.git

diff --git a/help/help/html/features/importvcf.html b/help/help/html/features/importvcf.html
index 511ff2e..7b699eb 100755
--- a/help/help/html/features/importvcf.html
+++ b/help/help/html/features/importvcf.html
@@ -72,6 +72,24 @@
     for more information.
   </p>
   <p>
+    <strong>Working with variants without CSQ fields</strong>
+  </p>
+  <p>
+    <a name="computepepvariants">Jalview 2.11.1's new virtual
+      features</a> mean that peptide sequences are no longer annotated
+    directly with protein missense variants. This makes it harder to
+    filter variants when they do not already include the CSQ field. You
+    can rescue the pre-2.11.1 functionality by:
+  </p>
+  <ol>
+    <li>Download the script at
+      https://www.jalview.org/examples/groovy/ComputePeptideVariants.groovy</li>
+    <li>Executing the script via the <a href="groovy.html">Groovy
+        Console</a> on a linked CDS/Protein view to create missense and
+      synonymous peptide variant features.
+    </li>
+  </ol>
+  <p>
     <strong>Working with variants from organisms other than
       H.sapiens.</strong>
   </p>