X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=help%2Fhtml%2Fcalculations%2Fpca.html;h=c38d9ac812f81b944c1909a63935924f5d418988;hb=dde303bc73617ab4eb3e681e67cf899e6a971318;hp=071a2b52e66e9e923679a1b94835ae2fae566344;hpb=528c0f1815bc67b54618ad5b16c2162946974caf;p=jalview.git diff --git a/help/html/calculations/pca.html b/help/html/calculations/pca.html index 071a2b5..c38d9ac 100755 --- a/help/html/calculations/pca.html +++ b/help/html/calculations/pca.html @@ -58,15 +58,15 @@ pair of sequences - computed with one of the available score matrices, such as BLOSUM62, PAM250, or the simple single nucleotide substitution matrix. The options - available for calculation are given in the Change + href="scorematrices.html#simplenucleotide">simple single + nucleotide substitution matrix. The options available for + calculation are given in the Change Parameters menu.

- PCA Calculation modes
The default Jalview calculation - mode (indicated when Jalview PCA - Calculation is ticked in the Change + PCA Calculation modes
The default Jalview + calculation mode (indicated when Jalview + PCA Calculation is ticked in the Change Parameters menu) is to perform a PCA on a matrix where elements in the upper diagonal give the sum of scores for mutating in one direction, and the lower diagonal is the sum of scores for mutating @@ -74,10 +74,10 @@ gives an asymmetric matrix, and a different PCA to a matrix produced with the method described in the paper by G. Casari, C. Sander and A. Valencia. Structural Biology volume 2, no. 2, February 1995 (pubmed) and implemented at the SeqSpace server at the EBI. This - method preconditions the matrix by multiplying it with its - transpose, and can be employed in the PCA viewer by unchecking the Jalview + href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=7749921">pubmed) + and implemented at the SeqSpace server at the EBI. This method + preconditions the matrix by multiplying it with its transpose, and + can be employed in the PCA viewer by unchecking the Jalview PCA Calculation option in the Change Parameters menu.