X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=help%2Fhtml%2Ffeatures%2Fsiftsmapping.html;h=c12d45bb11359d568c304a7fa222c537ef09cd01;hb=469c8fbe09f4e4c137f6255428116158bec823ac;hp=8913e4f173f0e0197074e2b5cae266ba96562e05;hpb=a9a8a71c1682f639552e9954e565042847513195;p=jalview.git diff --git a/help/html/features/siftsmapping.html b/help/html/features/siftsmapping.html index 8913e4f..c12d45b 100644 --- a/help/html/features/siftsmapping.html +++ b/help/html/features/siftsmapping.html @@ -1,4 +1,24 @@ + @@ -24,7 +44,8 @@ will generate a mapping using the built-in Needleman and Wunsch global alignment algorithm. This is how sequence-structure mappings were created before version 2.10.

-

Controlling and troubleshooting SIFTS mappings
+

+ Controlling and troubleshooting SIFTS mappings
Configuration options controlling whether SIFTS mappings are used can be found in the Tools → Preferences → Structure tab, under 'Sequence ↔ Structure method'.
Note: @@ -37,11 +58,12 @@ Multi-Chain Mappings
SIFTS gives Jalview the ability to display multi-chain mappings between UniProt sequences and PDB structure data. This is important when working with - multimeric proteins, when the biological assembly can contain several - structures for the same protein sequence. Multi-chain mapping allows - all residues in a structure to be located in the alignment, and - also, when shading the structure by sequence colours, enables - conservation patterns between oligomer interfaces to be explored. + multimeric proteins, when the biological assembly can contain + several structures for the same protein sequence. Multi-chain + mapping allows all residues in a structure to be located in the + alignment, and also, when shading the structure by sequence colours, + enables conservation patterns between oligomer interfaces to be + explored.

To see this in action, Retrieve the UniProt sequence FER1_MAIZE, and then view one of its structures: 3B2F. Mousing over @@ -53,16 +75,16 @@ Viewing Mapping Output
The mapping provided by the SIFTS record is accessible via File → View mapping menu of the structure viewers. The screenshot below - shows the mapping created between UniProt sequence FER1_MAIZE and proteins in PDB 3B2F, which reports that two chains - were mapped. The mapping method is also reported (highlighted with red border). + shows the mapping created between UniProt sequence FER1_MAIZE and + proteins in PDB 3B2F, which reports mappings for two chains. The + mapping method is also reported (highlighted with red border).

SIFTS mapping output -
+ alt="SIFTS mapping output" />

SIFTS Mapping integration was added in Jalview 2.10

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