X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fws%2Fdbsources%2FUniprot.java;h=167cd977d325a06d6ddf2d2128053715ecb772d6;hb=743af46c3c50e67706009be4360fa504bfcd4fdc;hp=73775cf07b247c8f5eadf7fc2b61f592c0550997;hpb=b5fb170aae86089a49a0529dbb4c04bf36e0499b;p=jalview.git

diff --git a/src/jalview/ws/dbsources/Uniprot.java b/src/jalview/ws/dbsources/Uniprot.java
index 73775cf..167cd97 100644
--- a/src/jalview/ws/dbsources/Uniprot.java
+++ b/src/jalview/ws/dbsources/Uniprot.java
@@ -20,6 +20,7 @@
  */
 package jalview.ws.dbsources;
 
+import jalview.bin.Cache;
 import jalview.datamodel.Alignment;
 import jalview.datamodel.AlignmentI;
 import jalview.datamodel.DBRefEntry;
@@ -31,6 +32,8 @@ import jalview.datamodel.SequenceI;
 import jalview.datamodel.xdb.uniprot.UniprotEntry;
 import jalview.datamodel.xdb.uniprot.UniprotFeature;
 import jalview.datamodel.xdb.uniprot.UniprotFile;
+import jalview.schemes.ResidueProperties;
+import jalview.util.StringUtils;
 import jalview.ws.seqfetcher.DbSourceProxyImpl;
 
 import java.io.InputStream;
@@ -39,6 +42,7 @@ import java.io.Reader;
 import java.net.URL;
 import java.net.URLConnection;
 import java.util.ArrayList;
+import java.util.List;
 import java.util.Vector;
 
 import org.exolab.castor.mapping.Mapping;
@@ -52,6 +56,8 @@ import com.stevesoft.pat.Regex;
  */
 public class Uniprot extends DbSourceProxyImpl
 {
+  private static final String DEFAULT_UNIPROT_DOMAIN = "https://www.uniprot.org";
+
   private static final String BAR_DELIMITER = "|";
 
   /*
@@ -67,6 +73,11 @@ public class Uniprot extends DbSourceProxyImpl
     super();
   }
 
+  private String getDomain()
+  {
+    return Cache.getDefault("UNIPROT_DOMAIN", DEFAULT_UNIPROT_DOMAIN);
+  }
+
   /*
    * (non-Javadoc)
    * 
@@ -163,7 +174,7 @@ public class Uniprot extends DbSourceProxyImpl
               "(UNIPROT\\|?|UNIPROT_|UNIREF\\d+_|UNIREF\\d+\\|?)", "");
       AlignmentI al = null;
 
-      String downloadstring = "http://www.uniprot.org/uniprot/" + queries
+      String downloadstring = getDomain() + "/uniprot/" + queries
               + ".xml";
       URL url = null;
       URLConnection urlconn = null;
@@ -270,7 +281,7 @@ public class Uniprot extends DbSourceProxyImpl
       for (UniprotFeature uf : entry.getFeature())
       {
         SequenceFeature copy = new SequenceFeature(uf.getType(),
-                uf.getDescription(), uf.getBegin(), uf.getEnd(), "Uniprot");
+                getDescription(uf), uf.getBegin(), uf.getEnd(), "Uniprot");
         copy.setStatus(uf.getStatus());
         sequence.addSequenceFeature(copy);
       }
@@ -283,6 +294,94 @@ public class Uniprot extends DbSourceProxyImpl
   }
 
   /**
+   * Constructs a feature description from the description and (optionally)
+   * original and variant fields of the Uniprot XML feature
+   * 
+   * @param uf
+   * @return
+   */
+  protected static String getDescription(UniprotFeature uf)
+  {
+    String orig = uf.getOriginal();
+    List<String> variants = uf.getVariation();
+    StringBuilder sb = new StringBuilder();
+
+    /*
+     * append variant in standard format if present
+     * e.g. p.Arg59Lys
+     * multiple variants are split over lines using <br>
+     */
+    boolean asHtml = false;
+    if (orig != null && !orig.isEmpty() && variants != null
+            && !variants.isEmpty())
+    {
+      int p = 0;
+      for (String var : variants)
+      {
+        // TODO proper HGVS nomenclature for delins structural variations
+        // http://varnomen.hgvs.org/recommendations/protein/variant/delins/
+        // for now we are pragmatic - any orig/variant sequence longer than
+        // three characters is shown with single-character notation rather than
+        // three-letter notation
+        sb.append("p.");
+        if (orig.length() < 4)
+        {
+          for (int c = 0, clen = orig.length(); c < clen; c++)
+          {
+            char origchar = orig.charAt(c);
+            String orig3 = ResidueProperties.aa2Triplet.get("" + origchar);
+            sb.append(orig3 == null ? origchar
+                    : StringUtils.toSentenceCase(orig3));
+          }
+        }
+        else
+        {
+          sb.append(orig);
+        }
+
+        sb.append(Integer.toString(uf.getPosition()));
+
+        if (var.length() < 4)
+        {
+          for (int c = 0, clen = var.length(); c < clen; c++)
+          {
+            char varchar = var.charAt(c);
+            String var3 = ResidueProperties.aa2Triplet.get("" + varchar);
+
+            sb.append(var3 != null ? StringUtils.toSentenceCase(var3)
+                    : "" + varchar);
+          }
+        }
+        else
+        {
+          sb.append(var);
+        }
+        if (++p != variants.size())
+        {
+          sb.append("<br/>&nbsp;&nbsp;");
+          asHtml = true;
+        }
+        else
+        {
+          sb.append(" ");
+        }
+      }
+    }
+    String description = uf.getDescription();
+    if (description != null)
+    {
+      sb.append(description);
+    }
+    if (asHtml)
+    {
+      sb.insert(0, "<html>");
+      sb.append("</html>");
+    }
+
+    return sb.toString();
+  }
+
+  /**
    * 
    * @param entry
    *          UniportEntry