From 0b1c6520810e954fab65058df5931a06f5c43e5d Mon Sep 17 00:00:00 2001 From: pvtroshin Date: Mon, 26 Jul 2010 18:23:44 +0000 Subject: [PATCH] Adding disembl wrapper git-svn-id: link to svn.lifesci.dundee.ac.uk/svn/barton/ptroshin/JABA2@2685 e3abac25-378b-4346-85de-24260fe3988d --- conf/Executable.properties | 11 +- conf/settings/DisemblParameters.xml | 19 + .../data/sequence/MultiAnnotatedSequence.java | 33 + datamodel/compbio/data/sequence/SequenceUtil.java | 7 + runner/compbio/runner/_impl/Disembl.java | 77 - runner/compbio/runner/_impl/Runners.java | 56 +- runner/compbio/runner/disorder/Disembl.java | 133 ++ runner/compbio/runner/disorder/GlobProt.java | 17 + testsrc/compbio/runner/_impl/DisEMBLTester.java | 96 -- testsrc/testdata/disembl.out | 1565 ++++++++++++++++++++ 10 files changed, 1810 insertions(+), 204 deletions(-) create mode 100644 conf/settings/DisemblParameters.xml create mode 100644 datamodel/compbio/data/sequence/MultiAnnotatedSequence.java delete mode 100644 runner/compbio/runner/_impl/Disembl.java create mode 100644 runner/compbio/runner/disorder/Disembl.java create mode 100644 runner/compbio/runner/disorder/GlobProt.java delete mode 100644 testsrc/compbio/runner/_impl/DisEMBLTester.java create mode 100644 testsrc/testdata/disembl.out diff --git a/conf/Executable.properties b/conf/Executable.properties index 6f66e35..0a9b5cd 100644 --- a/conf/Executable.properties +++ b/conf/Executable.properties @@ -65,6 +65,15 @@ cluster.jronn.bin=/sw/java/latest/bin/java jronn.jar.file=binaries/jronn3.1.jar jronn.parameters.file=conf/settings/JronnParameters.xml jronn.limits.file=conf/settings/JronnLimits.xml -jronn.jvm.options=-Xms32M -Xmx512M +#TODO jronn.jvm.options=-Xms32M -Xmx512M jronn.cluster.cpunum=4 jronn.cluster.settings=-q 64bit-pri.q -pe smp 4 -l h_vmem=1700M -l ram=1700M -l h_cpu=24:00:00 + + +### Disembl configuration - NOT DISTRIBUTED ### +#local.disembl.bin.windows= +local.disembl.bin=/homes/pvtroshin/soft/DisEMBL-1.4raw/DisEMBL.py +cluster.disembl.bin=/homes/pvtroshin/soft/DisEMBL-1.4raw/DisEMBL.py +#disembl.parameters.file=conf/settings/JronnParameters.xml +disembl.limits.file=conf/settings/JronnLimits.xml +disembl.cluster.settings=-l h_cpu=24:00:00 -l h_vmem=6000M -l ram=6000M diff --git a/conf/settings/DisemblParameters.xml b/conf/settings/DisemblParameters.xml new file mode 100644 index 0000000..9e50d5d --- /dev/null +++ b/conf/settings/DisemblParameters.xml @@ -0,0 +1,19 @@ + + + compbio.runner.disorder.Disembl + = + + Default parameters should not be changed! + Normally the default parameters should not be changed. + If the query protein sequence is very long, >1000 residues, you can download the predictions and + use a local graph/plotting tool such as Grace or OpenOffice.org to plot and zoom the data. + Having identified the potential disordered regions, you should now have a good basis for setting + up expression vectors and/or comparing the data with obtained structural data. + + -sg + prog_docs/disembl.html + 1 + + + + \ No newline at end of file diff --git a/datamodel/compbio/data/sequence/MultiAnnotatedSequence.java b/datamodel/compbio/data/sequence/MultiAnnotatedSequence.java new file mode 100644 index 0000000..580a22e --- /dev/null +++ b/datamodel/compbio/data/sequence/MultiAnnotatedSequence.java @@ -0,0 +1,33 @@ +package compbio.data.sequence; + +import java.util.EnumMap; +import java.util.List; + +/** + * TODO complete + * + * @author pvtroshin + * + * @param + * enum type + */ +public class MultiAnnotatedSequence> { + + private final EnumMap> annotation; + + private MultiAnnotatedSequence(Class type) { + this.annotation = new EnumMap>(type); + } + + // public MultiAnnotatedSequence getFloatInstance(FastaSequence fsequence) { + // return null; + //} + + public EnumMap> getIntegerInstance(Class enumeration) { + return new EnumMap>(enumeration); + } + + public EnumMap> getFloatInstance(Class enumeration) { + return new EnumMap>(enumeration); + } +} diff --git a/datamodel/compbio/data/sequence/SequenceUtil.java b/datamodel/compbio/data/sequence/SequenceUtil.java index f7c923a..99a8147 100644 --- a/datamodel/compbio/data/sequence/SequenceUtil.java +++ b/datamodel/compbio/data/sequence/SequenceUtil.java @@ -396,4 +396,11 @@ public final class SequenceUtil { } } + public static List readDisembl(final File result) + throws IOException, UnknownFileFormatException { + InputStream input = new FileInputStream(result); + List sequences = readJRonn(input); + input.close(); + return sequences; + } } diff --git a/runner/compbio/runner/_impl/Disembl.java b/runner/compbio/runner/_impl/Disembl.java deleted file mode 100644 index ceff5b9..0000000 --- a/runner/compbio/runner/_impl/Disembl.java +++ /dev/null @@ -1,77 +0,0 @@ -/* Copyright (c) 2009 Peter Troshin - * - * Jalview Web Services @version: 2.0 - * - * This library is free software; you can redistribute it and/or modify it under the terms of the - * Apache License version 2 as published by the Apache Software Foundation - * - * This library is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without - * even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the Apache - * License for more details. - * - * A copy of the license is in apache_license.txt. It is also available here: - * @see: http://www.apache.org/licenses/LICENSE-2.0.txt - * - * Any republication or derived work distributed in source code form - * must include this copyright and license notice. - */ -package compbio.runner._impl; - -import java.util.Arrays; -import java.util.List; - -import compbio.runner._SkeletalCommandBuilder; - -/* - @see - * Standard DisEMBL - * DisEMBL.py smooth_frame peak_frame join_frame fold_coils fold_hotloops fold_rem465 sequence_file - print 'A default run would be: ./DisEMBL.py 8 8 4 1.2 1.4 1.2 fasta_file > out' - - new DisEMBL is at /homes/pvtroshin/soft/DisEMBL-1.4raw - This is not a standard DisEMBL! The script has been modified! - DisEMBL.py smooth_frame peak_frame join_frame fold_coils fold_hotloops fold_rem465 [mode] < fasta_file > out - print 'A default run would be: ./DisEMBL.py 8 8 4 1.2 1.4 1.2 < fasta_file' - print 'Mode: "default"(nothing) or "scores" which will give scores per residue in TAB separated format' - */ -public class Disembl extends _SkeletalCommandBuilder { - - private static final String command = "/homes/pvtroshin/soft/DisEMBL-1.4raw/DisEMBL.py"; - static final List params = Arrays.asList(new String[] { "8", "8", - "4", "1.2", "1.4", "1.2", "scores" }); - - private final String workDirectory; - - public Disembl(String workDirectory) { - this.workDirectory = workDirectory; - } - - public static List getTestArgs() { - return params; - } - - public String getCommand(ExecProvider provider) { - return command; - } - - public static String getTestCommand() { - return command; - } - - public String getCommandName() { - return "DisEMBL"; - } - - @Override - public List getCreatedFiles() { - // TODO Auto-generated method stub - return null; - } - - @Override - public String getInput() { - // TODO Auto-generated method stub - return null; - } - -} diff --git a/runner/compbio/runner/_impl/Runners.java b/runner/compbio/runner/_impl/Runners.java index e553c24..9c45eb1 100644 --- a/runner/compbio/runner/_impl/Runners.java +++ b/runner/compbio/runner/_impl/Runners.java @@ -19,43 +19,39 @@ package compbio.runner._impl; public final class Runners { - private Runners() { - } + private Runners() { + } - public static Mcl getMclRunnable(String workDirectory) { - return new Mcl(workDirectory); - } + public static Mcl getMclRunnable(String workDirectory) { + return new Mcl(workDirectory); + } - public static OB getOBRunnable(String workDirectory) { - return new OB(workDirectory); - } + public static OB getOBRunnable(String workDirectory) { + return new OB(workDirectory); + } - public static Disembl getDisemblRunnable(String workDirectory) { - return new Disembl(workDirectory); - } + public static NetNglyc getNetNglycRunnable(String workDirectory) { + return new NetNglyc(); + } - public static NetNglyc getNetNglycRunnable(String workDirectory) { - return new NetNglyc(); - } + public static Ronn getRonnRunnable(String workDirectory) { + return new Ronn(workDirectory); + } - public static Ronn getRonnRunnable(String workDirectory) { - return new Ronn(workDirectory); - } + public static Tmhmm2 getTmhmm2Runnable(String workDirectory) { + return new Tmhmm2(workDirectory); + } - public static Tmhmm2 getTmhmm2Runnable(String workDirectory) { - return new Tmhmm2(workDirectory); - } + public static RPSBlast getRPSBlastRunnable(String workDirectory) { + return new RPSBlast(workDirectory); + } - public static RPSBlast getRPSBlastRunnable(String workDirectory) { - return new RPSBlast(workDirectory); - } + public static BlastAll getBlastAllRunnable(String workDirectory) { + return new BlastAll(workDirectory); + } - public static BlastAll getBlastAllRunnable(String workDirectory) { - return new BlastAll(workDirectory); - } - - public static PSIBlast getPSIBlastRunnable(String workDirectory) { - return new PSIBlast(workDirectory); - } + public static PSIBlast getPSIBlastRunnable(String workDirectory) { + return new PSIBlast(workDirectory); + } } diff --git a/runner/compbio/runner/disorder/Disembl.java b/runner/compbio/runner/disorder/Disembl.java new file mode 100644 index 0000000..4c76854 --- /dev/null +++ b/runner/compbio/runner/disorder/Disembl.java @@ -0,0 +1,133 @@ +/* Copyright (c) 2009 Peter Troshin + * + * JAva Bioinformatics Analysis Web Services (JABAWS) @version: 1.0 + * + * This library is free software; you can redistribute it and/or modify it under the terms of the + * Apache License version 2 as published by the Apache Software Foundation + * + * This library is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without + * even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the Apache + * License for more details. + * + * A copy of the license is in apache_license.txt. It is also available here: + * @see: http://www.apache.org/licenses/LICENSE-2.0.txt + * + * Any republication or derived work distributed in source code form + * must include this copyright and license notice. + */ + +package compbio.runner.disorder; + +import java.io.FileNotFoundException; +import java.io.IOException; +import java.util.Arrays; + +import org.apache.log4j.Logger; + +import com.sun.xml.internal.bind.api.impl.NameConverter.Standard; +import compbio.data.sequence.Alignment; +import compbio.data.sequence.UnknownFileFormatException; +import compbio.engine.client.Executable; +import compbio.engine.client.PipedExecutable; +import compbio.engine.client.SkeletalExecutable; +import compbio.metadata.Limit; +import compbio.metadata.LimitsManager; +import compbio.metadata.ResultNotAvailableException; +import compbio.runner.Util; + +/** + * @see Standard DisEMBL DisEMBL.py smooth_frame peak_frame join_frame + * fold_coils fold_hotloops fold_rem465 sequence_file print 'A default run + * would be: ./DisEMBL.py 8 8 4 1.2 1.4 1.2 fasta_file > out' + * + * new DisEMBL is at /homes/pvtroshin/soft/DisEMBL-1.4raw This is not a + * standard DisEMBL! The script has been modified! DisEMBL.py smooth_frame + * peak_frame join_frame fold_coils fold_hotloops fold_rem465 [mode] < + * fasta_file > out print 'A default run would be: ./DisEMBL.py 8 8 4 1.2 + * 1.4 1.2 < fasta_file' print 'Mode: "default"(nothing) or "scores" which + * will give scores per residue in TAB separated format' + * + */ +public class Disembl extends SkeletalExecutable implements + PipedExecutable { + + private static Logger log = Logger.getLogger(Disembl.class); + + // Cache for Limits information + private static LimitsManager limits; + + public static final String KEY_VALUE_SEPARATOR = Util.SPACE; + + public Disembl() { + // remove default input to prevent it to appear in the parameters list + // that could happen if the parameters are set first + // super.setInput(""); + addParameters(Arrays.asList("8", "8", "4", "1.2", "1.4", "1.2", + "scores")); + } + + @SuppressWarnings("unchecked") + public Alignment getResults(String workDirectory) + throws ResultNotAvailableException { + try { + return Util.readClustalFile(workDirectory, getOutput()); + } catch (FileNotFoundException e) { + log.error(e.getMessage(), e.getCause()); + throw new ResultNotAvailableException(e); + } catch (IOException e) { + log.error(e.getMessage(), e.getCause()); + throw new ResultNotAvailableException(e); + } catch (UnknownFileFormatException e) { + log.error(e.getMessage(), e.getCause()); + throw new ResultNotAvailableException(e); + } catch (NullPointerException e) { + log.error(e.getMessage(), e.getCause()); + throw new ResultNotAvailableException(e); + } + } + + @Override + public Disembl setInput(String inFile) { + super.setInput(inFile); + cbuilder.setLast(inFile); + return this; + } + + @Override + public Limit getLimit(String presetName) { + if (limits == null) { + limits = getLimits(); + } + + Limit limit = null; + if (limits != null) { + // this returns default limit if preset is undefined! + limit = limits.getLimitByName(presetName); + } + // If limit is not defined for a particular preset, then return default + // limit + if (limit == null) { + log.debug("Limit for the preset " + presetName + + " is not found. Using default"); + limit = limits.getDefaultLimit(); + } + return limit; + } + + @Override + public LimitsManager getLimits() { + // synchronise on static field + synchronized (log) { + if (limits == null) { + limits = Util.getLimits(this.getClass()); + } + } + return limits; + } + + @Override + public Class> getType() { + return this.getClass(); + } + +} diff --git a/runner/compbio/runner/disorder/GlobProt.java b/runner/compbio/runner/disorder/GlobProt.java new file mode 100644 index 0000000..4ef7a3f --- /dev/null +++ b/runner/compbio/runner/disorder/GlobProt.java @@ -0,0 +1,17 @@ +package compbio.runner.disorder; + +/** + * + * ./GlobPipe.py SmoothFrame DOMjoinFrame DOMpeakFrame DISjoinFrame DISpeakFrame + * FASTAfile + * + * Optimised for ELM: ./GlobPlot.py 10 8 75 8 8 sequence_file + * + * Webserver settings: ./GlobPlot.py 10 15 74 4 5 sequence_file + * + * @author pvtroshin + * + */ +public class GlobProt { + +} diff --git a/testsrc/compbio/runner/_impl/DisEMBLTester.java b/testsrc/compbio/runner/_impl/DisEMBLTester.java deleted file mode 100644 index 5386a18..0000000 --- a/testsrc/compbio/runner/_impl/DisEMBLTester.java +++ /dev/null @@ -1,96 +0,0 @@ -/* Copyright (c) 2009 Peter Troshin - * - * JAva Bioinformatics Analysis Web Services (JABAWS) @version: 1.0 - * - * This library is free software; you can redistribute it and/or modify it under the terms of the - * Apache License version 2 as published by the Apache Software Foundation - * - * This library is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without - * even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the Apache - * License for more details. - * - * A copy of the license is in apache_license.txt. It is also available here: - * @see: http://www.apache.org/licenses/LICENSE-2.0.txt - * - * Any republication or derived work distributed in source code form - * must include this copyright and license notice. - */ -package compbio.runner._impl; - -import static org.testng.AssertJUnit.assertEquals; -import static org.testng.AssertJUnit.assertFalse; -import static org.testng.AssertJUnit.assertNotNull; -import static org.testng.AssertJUnit.assertTrue; -import static org.testng.AssertJUnit.fail; - -import java.text.ParseException; - -import org.ggf.drmaa.DrmaaException; -import org.ggf.drmaa.JobInfo; -import org.testng.annotations.Test; - -import compbio.engine.cluster.drmaa.ClusterUtil; -import compbio.engine.cluster.drmaa.JobRunner; -import compbio.engine.cluster.drmaa.StatisticManager; -import compbio.metadata.AllTestSuit; -import compbio.metadata.JobExecutionException; -import compbio.metadata.JobStatus; -import compbio.metadata.JobSubmissionException; - -public class DisEMBLTester { - - public static String test_input = "/homes/pvtroshin/TO1381.fasta"; - public static String test_outfile = "/homes/pvtroshin/TO1381.disEMBL.out"; - - @Test(enabled = false, groups = { AllTestSuit.test_group_cluster, - AllTestSuit.test_group_runner }) - public void testBuildCommand() { - Disembl disembl = new Disembl(AllTestSuit.OUTPUT_DIR_ABSOLUTE); - // TODO - // disembl.setInput(test_input).setOutput(test_outfile); - - try { - - JobRunner runner = JobRunner.getInstance(null); - - assertNotNull("Runner is NULL", runner); - runner.executeJob(); - // assertNotNull("JobId is null", jobId1); - JobStatus status = runner.getJobStatus(); - assertTrue("Status of the process is wrong!", - status == JobStatus.PENDING || status == JobStatus.RUNNING); - JobInfo info = runner.getJobInfo(); - assertNotNull("JobInfo is null", info); - StatisticManager sm = new StatisticManager(info); - assertNotNull("Statictic manager is null", sm); - try { - - String exits = sm.getExitStatus(); - assertNotNull("Exit status is null", exits); - int exitsInt = ClusterUtil.CLUSTER_STAT_IN_SEC.parse(exits) - .intValue(); - assertEquals("Exit status is not 0", 0, exitsInt); - System.out.println(sm.getAllStats()); - - } catch (ParseException e) { - e.printStackTrace(); - fail("Parse Exception: " + e.getMessage()); - } - - assertTrue("Process exited:", sm.hasExited()); - assertFalse("Process aborted:", sm.wasAborted()); - assertFalse("Process hasdump:", sm.hasDump()); - assertFalse("Process signaled:", sm.hasSignaled()); - - } catch (JobSubmissionException e) { - e.printStackTrace(); - fail("DrmaaException caught:" + e.getMessage()); - } catch (DrmaaException e) { - e.printStackTrace(); - fail("DrmaaException caught:" + e.getMessage()); - } catch (JobExecutionException e) { - e.printStackTrace(); - fail("DrmaaException caught:" + e.getMessage()); - } - } -} diff --git a/testsrc/testdata/disembl.out b/testsrc/testdata/disembl.out new file mode 100644 index 0000000..06011cc --- /dev/null +++ b/testsrc/testdata/disembl.out @@ -0,0 +1,1565 @@ +# RESIDUE COILS REM465 HOTLOOPS +M 0.86010 0.88512 0.37094 +T 0.79983 0.85864 0.44331 +A 0.72031 0.83329 0.42744 +D 0.62168 0.79393 0.24390 +G 0.50983 0.59080 0.11673 +P 0.25998 0.36247 0.06320 +R 0.29879 0.44037 0.06982 +E 0.25286 0.32959 0.05194 +L 0.21085 0.31715 0.04783 +L 0.17763 0.27760 0.02311 +Q 0.16044 0.27182 0.01845 +L 0.18476 0.27532 0.04620 +R 0.22259 0.29066 0.06996 +A 0.26044 0.31137 0.08420 +A 0.28021 0.31834 0.09161 +V 0.31770 0.33024 0.09771 +R 0.34459 0.33123 0.10017 +H 0.35438 0.33015 0.10042 +R 0.34941 0.31879 0.09479 +P 0.33860 0.29840 0.08436 +Q 0.31280 0.26756 0.07276 +D 0.27741 0.22690 0.06044 +F 0.25835 0.18412 0.05193 +V 0.22091 0.15604 0.03427 +A 0.19781 0.13840 0.02145 +W 0.17252 0.12069 0.00934 +L 0.16471 0.13344 0.00824 +M 0.18962 0.14399 0.02030 +L 0.20990 0.15715 0.02233 +A 0.24890 0.18675 0.02482 +D 0.30416 0.20404 0.02828 +A 0.36864 0.21878 0.03293 +E 0.42323 0.24384 0.03802 +L 0.49613 0.27329 0.04467 +G 0.54673 0.30276 0.04821 +M 0.58288 0.32961 0.05112 +G 0.58734 0.35779 0.05103 +D 0.57351 0.39639 0.04991 +T 0.54838 0.40374 0.04728 +T 0.49719 0.41796 0.04257 +A 0.44247 0.42299 0.03589 +G 0.38488 0.42355 0.03230 +E 0.32062 0.43459 0.02845 +M 0.27621 0.43599 0.02370 +A 0.24947 0.43579 0.02298 +V 0.26104 0.44630 0.02480 +Q 0.28555 0.42657 0.02998 +R 0.33863 0.41808 0.03700 +G 0.42083 0.41277 0.04747 +L 0.52012 0.40903 0.05937 +A 0.57192 0.40310 0.06615 +L 0.61014 0.39172 0.07155 +H 0.62000 0.38603 0.07143 +P 0.61420 0.38863 0.07132 +G 0.59027 0.36809 0.06880 +H 0.54439 0.37383 0.06386 +P 0.50222 0.36429 0.05768 +E 0.45498 0.35329 0.05279 +A 0.40408 0.33619 0.04550 +V 0.36729 0.33364 0.03718 +A 0.33908 0.34380 0.03627 +R 0.34141 0.35219 0.03640 +L 0.35060 0.35611 0.03942 +G 0.37329 0.36835 0.04165 +R 0.39930 0.37477 0.04556 +V 0.41249 0.38955 0.04707 +R 0.40000 0.39924 0.04544 +W 0.38778 0.41158 0.04330 +T 0.36202 0.43951 0.03890 +Q 0.32894 0.45950 0.03453 +Q 0.29139 0.46461 0.03096 +R 0.24944 0.47555 0.02594 +H 0.22078 0.46457 0.02235 +A 0.18668 0.44830 0.01686 +E 0.15893 0.41673 0.01509 +A 0.13593 0.41862 0.01529 +A 0.13590 0.41297 0.02241 +V 0.16183 0.39515 0.02782 +L 0.19353 0.40028 0.03466 +L 0.24663 0.40988 0.04213 +Q 0.31725 0.43753 0.04908 +Q 0.38948 0.45652 0.05581 +A 0.46684 0.49088 0.06222 +S 0.54056 0.51927 0.06666 +D 0.60106 0.54082 0.06870 +A 0.64620 0.53213 0.06829 +A 0.66751 0.51461 0.06782 +P 0.65871 0.48304 0.06293 +E 0.61353 0.45002 0.05575 +H 0.54564 0.40062 0.04662 +P 0.48933 0.35331 0.04148 +G 0.42808 0.30441 0.03594 +I 0.39194 0.24590 0.03330 +A 0.35118 0.18098 0.02877 +L 0.33052 0.16960 0.02819 +W 0.32568 0.16924 0.02737 +L 0.32371 0.18936 0.02656 +G 0.33488 0.20189 0.02826 +H 0.35178 0.23060 0.02991 +A 0.36475 0.26267 0.03080 +L 0.36778 0.29931 0.03102 +E 0.35647 0.34612 0.03008 +D 0.32886 0.40965 0.02761 +A 0.28835 0.44616 0.02340 +G 0.22931 0.48443 0.01894 +Q 0.19242 0.49768 0.01648 +A 0.17246 0.51975 0.01495 +E 0.14513 0.52485 0.01265 +A 0.14509 0.52733 0.01241 +A 0.13113 0.52307 0.01172 +A 0.14257 0.52022 0.00727 +A 0.15732 0.49780 0.00925 +A 0.16228 0.47742 0.01891 +Y 0.19799 0.44287 0.03106 +T 0.24619 0.40365 0.03941 +R 0.30467 0.37339 0.05366 +A 0.38077 0.34312 0.06721 +H 0.44188 0.32533 0.07549 +Q 0.49887 0.30498 0.07979 +L 0.56428 0.26520 0.08702 +L 0.60765 0.24710 0.09515 +P 0.62855 0.22427 0.09743 +E 0.61894 0.22200 0.09484 +E 0.59193 0.21352 0.08797 +P 0.55817 0.21264 0.07919 +Y 0.50412 0.20699 0.06826 +I 0.45257 0.20568 0.05530 +T 0.38361 0.21586 0.05098 +A 0.31311 0.22920 0.04859 +Q 0.25850 0.23918 0.04120 +L 0.22610 0.24305 0.03398 +L 0.20761 0.24496 0.03393 +N 0.21606 0.24725 0.03076 +W 0.21665 0.23931 0.02528 +R 0.24919 0.22444 0.02444 +R 0.29430 0.21166 0.02930 +R 0.31798 0.20457 0.03067 +L 0.33694 0.18726 0.03113 +C 0.34845 0.17414 0.03145 +D 0.36210 0.16875 0.03166 +W 0.37031 0.16887 0.03294 +R 0.37025 0.16619 0.03378 +A 0.35790 0.18814 0.03081 +L 0.33779 0.21887 0.03011 +D 0.30930 0.24621 0.02892 +V 0.26754 0.27678 0.02676 +L 0.23659 0.32224 0.02315 +S 0.20691 0.35984 0.02471 +A 0.17775 0.39641 0.02215 +Q 0.15081 0.42204 0.02329 +V 0.14823 0.43457 0.02579 +R 0.15588 0.44450 0.02810 +A 0.18517 0.44995 0.03299 +A 0.22282 0.44130 0.03871 +V 0.26328 0.41804 0.04349 +A 0.31092 0.40182 0.04799 +Q 0.35060 0.36068 0.05071 +G 0.38352 0.32101 0.05107 +V 0.42164 0.29133 0.05083 +G 0.45736 0.26373 0.05326 +A 0.49886 0.22661 0.05499 +V 0.52391 0.20562 0.05560 +E 0.53303 0.20165 0.05326 +P 0.53975 0.20063 0.05487 +F 0.52385 0.20385 0.05015 +A 0.50639 0.22752 0.05004 +F 0.48741 0.26114 0.04785 +L 0.46674 0.28999 0.04586 +S 0.43909 0.33263 0.04388 +E 0.39696 0.36707 0.03940 +D 0.35208 0.41809 0.03515 +A 0.30408 0.46253 0.03007 +S 0.24901 0.46649 0.02454 +A 0.19867 0.47834 0.01929 +A 0.16075 0.50072 0.01365 +E 0.13788 0.50748 0.01122 +Q 0.13506 0.50876 0.01368 +L 0.12169 0.51337 0.01547 +A 0.12136 0.51136 0.01598 +C 0.13259 0.50633 0.01649 +A 0.13448 0.48088 0.01786 +R 0.13417 0.48245 0.02171 +T 0.14810 0.47380 0.02092 +R 0.15594 0.46796 0.02898 +A 0.16180 0.47356 0.03389 +Q 0.19117 0.47436 0.04219 +A 0.22511 0.46346 0.05995 +I 0.26575 0.46364 0.06867 +A 0.31723 0.44786 0.08230 +A 0.37505 0.45856 0.10196 +S 0.43341 0.46499 0.12734 +V 0.50181 0.46517 0.14401 +R 0.55621 0.45469 0.15645 +P 0.60375 0.45290 0.17581 +L 0.64486 0.44417 0.18570 +A 0.66990 0.43379 0.19070 +P 0.68382 0.41168 0.18878 +T 0.70233 0.41020 0.18048 +R 0.72070 0.40484 0.16987 +V 0.71180 0.39972 0.16069 +R 0.71532 0.37964 0.14413 +S 0.70293 0.35656 0.12867 +K 0.67155 0.32107 0.11402 +G 0.63844 0.31759 0.08838 +P 0.61151 0.28482 0.07748 +L 0.58165 0.26357 0.07057 +R 0.56607 0.23944 0.06683 +V 0.55583 0.20985 0.05244 +G 0.54798 0.18271 0.04783 +F 0.54729 0.18625 0.06066 +V 0.56353 0.19115 0.06687 +S 0.58514 0.20302 0.07328 +N 0.61899 0.21760 0.07727 +G 0.64417 0.24094 0.08164 +F 0.66852 0.25410 0.08724 +G 0.67113 0.26439 0.08635 +A 0.65329 0.26395 0.08354 +H 0.59906 0.25471 0.07613 +P 0.53852 0.23852 0.06676 +T 0.46756 0.23838 0.05520 +G 0.39638 0.22887 0.04532 +L 0.32435 0.21985 0.03424 +L 0.25959 0.20622 0.02455 +T 0.21092 0.19002 0.01454 +V 0.16286 0.18984 0.00874 +A 0.13222 0.19663 0.01040 +L 0.13718 0.21327 0.01176 +F 0.15922 0.22668 0.01421 +E 0.19287 0.25014 0.01571 +A 0.24795 0.27481 0.02231 +L 0.30912 0.29319 0.02781 +Q 0.36600 0.31761 0.03436 +R 0.40904 0.32357 0.04039 +R 0.44641 0.31944 0.04550 +Q 0.47387 0.31066 0.04911 +P 0.48015 0.30088 0.05001 +D 0.46585 0.27977 0.04718 +L 0.43848 0.26224 0.04029 +Q 0.41204 0.24283 0.03653 +M 0.40286 0.22376 0.03416 +H 0.38445 0.22935 0.04559 +L 0.40616 0.24686 0.05506 +F 0.44756 0.28038 0.07106 +A 0.47610 0.30637 0.08409 +T 0.52735 0.35044 0.09517 +S 0.56587 0.38896 0.10535 +G 0.57757 0.43154 0.10837 +D 0.58300 0.46681 0.10980 +D 0.55714 0.47586 0.10507 +G 0.52225 0.46343 0.09636 +S 0.49037 0.44504 0.08443 +T 0.44095 0.43528 0.06889 +L 0.37153 0.42133 0.04888 +R 0.31143 0.39708 0.03105 +T 0.27726 0.37781 0.01676 +R 0.27155 0.36109 0.01414 +L 0.28212 0.36818 0.02699 +A 0.32672 0.37349 0.03457 +Q 0.37520 0.37718 0.04759 +A 0.40565 0.37791 0.05522 +S 0.43709 0.38006 0.06145 +T 0.42865 0.37978 0.06213 +L 0.42653 0.37779 0.06203 +H 0.41799 0.35467 0.06181 +D 0.40044 0.33312 0.05776 +V 0.40150 0.31093 0.05556 +T 0.41246 0.30646 0.05349 +A 0.40495 0.29640 0.05083 +L 0.38425 0.29841 0.04063 +G 0.37341 0.31172 0.03907 +H 0.37246 0.32334 0.03285 +L 0.38933 0.33516 0.04222 +A 0.38737 0.36073 0.05225 +T 0.39737 0.37986 0.06044 +A 0.39716 0.39982 0.06460 +K 0.37829 0.40866 0.06597 +H 0.35046 0.39889 0.06465 +I 0.32903 0.38932 0.06095 +R 0.31342 0.37365 0.05668 +H 0.28853 0.35140 0.05380 +H 0.27629 0.33450 0.04777 +G 0.29822 0.30711 0.04648 +I 0.31666 0.28368 0.04202 +D 0.33323 0.24918 0.03960 +L 0.35823 0.24361 0.03424 +L 0.39797 0.22750 0.04012 +F 0.44639 0.21384 0.04190 +D 0.50116 0.22639 0.05091 +L 0.55514 0.24972 0.05808 +R 0.61133 0.27218 0.06250 +G 0.66599 0.28765 0.06599 +W 0.70960 0.29860 0.06791 +G 0.73011 0.30278 0.06742 +G 0.72946 0.30915 0.06371 +G 0.71108 0.30904 0.06168 +G 0.68003 0.30934 0.05571 +R 0.66061 0.29289 0.04656 +P 0.64635 0.27540 0.05550 +E 0.62499 0.25806 0.06154 +V 0.62287 0.23817 0.06756 +F 0.61060 0.22593 0.07470 +A 0.59656 0.21864 0.08205 +L 0.60330 0.21961 0.08723 +R 0.62421 0.23110 0.09194 +P 0.63973 0.23597 0.09437 +A 0.63254 0.24152 0.09269 +P 0.63711 0.23203 0.08998 +V 0.62232 0.23166 0.08314 +Q 0.60255 0.21849 0.07443 +V 0.59309 0.19996 0.06600 +N 0.59586 0.18959 0.05853 +W 0.59987 0.19889 0.04827 +L 0.61528 0.19585 0.04572 +A 0.65515 0.21571 0.05698 +Y 0.69371 0.23266 0.05857 +P 0.73439 0.25305 0.06008 +G 0.74188 0.26312 0.06422 +T 0.75123 0.27052 0.06498 +S 0.76951 0.26451 0.06622 +G 0.76779 0.25325 0.06613 +A 0.72111 0.23147 0.06174 +P 0.67480 0.21248 0.05747 +W 0.62753 0.18266 0.05294 +M 0.56914 0.15468 0.04739 +D 0.51707 0.12451 0.04297 +Y 0.48676 0.10065 0.04061 +V 0.46016 0.10000 0.03796 +L 0.45125 0.09899 0.03673 +G 0.46512 0.11515 0.03756 +D 0.49575 0.13961 0.03981 +A 0.52466 0.15857 0.04193 +F 0.57603 0.17730 0.04653 +A 0.62643 0.18387 0.05093 +L 0.66695 0.17936 0.05452 +P 0.71435 0.19585 0.05745 +P 0.73410 0.21047 0.05962 +A 0.73013 0.21125 0.06018 +L 0.72402 0.22164 0.06056 +E 0.69564 0.22568 0.05896 +P 0.63984 0.23915 0.05487 +F 0.58543 0.24806 0.05085 +Y 0.52763 0.26149 0.04642 +S 0.44437 0.27688 0.03734 +E 0.38994 0.28580 0.03378 +H 0.35698 0.32239 0.03272 +V 0.33694 0.33489 0.03170 +L 0.34704 0.33592 0.03225 +R 0.38340 0.34142 0.03633 +L 0.42595 0.35345 0.04216 +Q 0.47377 0.35116 0.04156 +G 0.54491 0.39114 0.05373 +A 0.59484 0.41648 0.06565 +F 0.64512 0.44408 0.07508 +Q 0.68398 0.47392 0.08236 +P 0.71015 0.50429 0.08796 +S 0.72130 0.54316 0.08945 +D 0.74023 0.56084 0.08986 +T 0.73744 0.58262 0.08960 +S 0.72650 0.59894 0.08635 +R 0.73237 0.61200 0.08672 +V 0.74400 0.63068 0.08153 +V 0.74773 0.62745 0.07749 +A 0.76058 0.62126 0.07520 +E 0.76800 0.60970 0.07795 +P 0.77430 0.59118 0.07922 +P 0.78245 0.55519 0.07148 +S 0.80137 0.54121 0.08379 +R 0.81007 0.51724 0.09656 +T 0.81403 0.49308 0.10518 +Q 0.80079 0.45171 0.11149 +C 0.78528 0.41673 0.11452 +G 0.76190 0.37530 0.11100 +L 0.71814 0.32633 0.10722 +P 0.67495 0.28305 0.10562 +E 0.62661 0.24178 0.09856 +Q 0.56985 0.20651 0.08806 +G 0.52558 0.17933 0.07590 +V 0.47230 0.15205 0.06666 +V 0.43535 0.13419 0.05794 +L 0.40715 0.11369 0.05152 +C 0.41016 0.10273 0.04279 +C 0.43433 0.09879 0.03559 +F 0.50619 0.10500 0.04489 +N 0.57712 0.12335 0.05514 +N 0.62439 0.14604 0.05781 +S 0.63807 0.18419 0.05701 +Y 0.64582 0.21583 0.05612 +K 0.62340 0.24793 0.05276 +L 0.57371 0.28206 0.05093 +N 0.52540 0.29710 0.04927 +P 0.45482 0.31328 0.04325 +Q 0.37909 0.31568 0.03689 +S 0.29692 0.30541 0.02973 +M 0.21762 0.29356 0.02260 +A 0.15041 0.26998 0.01661 +R 0.09545 0.24528 0.01214 +M 0.08442 0.22763 0.01056 +L 0.11346 0.21969 0.01251 +A 0.16837 0.21275 0.01654 +V 0.22297 0.21879 0.02025 +L 0.26784 0.22602 0.02408 +R 0.30242 0.24476 0.02673 +E 0.33874 0.25182 0.03097 +V 0.34959 0.27168 0.03150 +P 0.33978 0.27434 0.03121 +D 0.33332 0.27763 0.03094 +S 0.32976 0.29445 0.03047 +V 0.35623 0.29670 0.03296 +L 0.37151 0.28190 0.03391 +W 0.39865 0.29676 0.03479 +L 0.41861 0.30967 0.03663 +L 0.43481 0.32817 0.03818 +S 0.45442 0.35277 0.04037 +G 0.46433 0.36330 0.04162 +P 0.46649 0.36202 0.04203 +G 0.46746 0.36549 0.04237 +E 0.44268 0.35150 0.04112 +A 0.39880 0.34825 0.03745 +D 0.34362 0.33941 0.03023 +A 0.27079 0.32740 0.02553 +R 0.19685 0.30861 0.02129 +L 0.15646 0.30589 0.01928 +R 0.14567 0.30763 0.01266 +A 0.17408 0.31707 0.01691 +F 0.21654 0.33503 0.02252 +A 0.26349 0.38717 0.03069 +H 0.32359 0.41084 0.04191 +A 0.38144 0.41639 0.05518 +Q 0.43067 0.42053 0.06218 +G 0.47270 0.40240 0.07489 +V 0.50814 0.38341 0.08407 +D 0.52289 0.35372 0.08916 +A 0.53947 0.31127 0.09208 +Q 0.55178 0.27810 0.09175 +R 0.56301 0.23283 0.08799 +L 0.57426 0.19651 0.08755 +V 0.59531 0.17737 0.08383 +F 0.60326 0.15396 0.07657 +M 0.62804 0.16806 0.06773 +P 0.65584 0.19021 0.06801 +K 0.68140 0.21968 0.06499 +L 0.68264 0.23978 0.06242 +P 0.68490 0.24644 0.06013 +H 0.68668 0.26272 0.05960 +P 0.67935 0.27414 0.05542 +Q 0.64507 0.26988 0.05695 +Y 0.60140 0.26219 0.05228 +L 0.56330 0.24327 0.04858 +A 0.55438 0.22917 0.04645 +R 0.52210 0.21007 0.04306 +Y 0.51021 0.18991 0.04170 +R 0.50118 0.17798 0.03976 +H 0.49408 0.17028 0.04134 +A 0.49113 0.14885 0.04276 +D 0.52093 0.14786 0.04658 +L 0.54598 0.14366 0.04963 +F 0.57162 0.15295 0.05237 +L 0.59979 0.15882 0.05418 +D 0.62941 0.18150 0.05724 +T 0.66631 0.19936 0.05978 +H 0.69373 0.21439 0.06162 +P 0.70792 0.24334 0.06451 +Y 0.73006 0.28913 0.06664 +N 0.73659 0.31948 0.05917 +A 0.74324 0.35862 0.06255 +H 0.69816 0.38328 0.06584 +T 0.66515 0.40185 0.07276 +T 0.61727 0.40648 0.07578 +A 0.59280 0.40090 0.08299 +S 0.58091 0.37470 0.08683 +D 0.58233 0.35162 0.08915 +A 0.59138 0.32705 0.09026 +L 0.59940 0.29487 0.08907 +W 0.61086 0.25952 0.08583 +T 0.63117 0.23415 0.08354 +G 0.64088 0.20701 0.07736 +C 0.66172 0.19254 0.07067 +P 0.69118 0.20234 0.06654 +V 0.70553 0.22105 0.05918 +L 0.70208 0.22639 0.05011 +T 0.68245 0.24682 0.05419 +T 0.62544 0.25800 0.05278 +P 0.56988 0.27315 0.05171 +G 0.51318 0.28596 0.04768 +E 0.46788 0.29210 0.04443 +T 0.41726 0.29146 0.04050 +F 0.36734 0.29524 0.03603 +A 0.32063 0.28693 0.03220 +A 0.26832 0.28731 0.02700 +R 0.24681 0.28867 0.02490 +V 0.24436 0.29256 0.02440 +A 0.24656 0.29313 0.02350 +G 0.27373 0.28458 0.02360 +S 0.32678 0.28414 0.02955 +L 0.37613 0.28419 0.03492 +N 0.42874 0.27040 0.03982 +H 0.47657 0.25552 0.04416 +H 0.53361 0.24348 0.04881 +L 0.56876 0.23408 0.05143 +G 0.59975 0.22377 0.05394 +L 0.61704 0.21744 0.05507 +D 0.62577 0.21108 0.05533 +E 0.61075 0.20183 0.05320 +M 0.58173 0.20394 0.05023 +N 0.53686 0.21602 0.04574 +V 0.49281 0.21370 0.04199 +A 0.42644 0.21815 0.03603 +D 0.36426 0.22473 0.03003 +D 0.30930 0.22202 0.02475 +A 0.26382 0.22207 0.02141 +A 0.20346 0.22812 0.01511 +F 0.16652 0.23306 0.01146 +V 0.13737 0.25019 0.00886 +A 0.12949 0.26687 0.00225 +K 0.15808 0.27795 0.01186 +A 0.21339 0.29573 0.02783 +V 0.26353 0.31670 0.04126 +A 0.31427 0.32406 0.05199 +L 0.36375 0.33586 0.06233 +A 0.39713 0.35160 0.06954 +S 0.41552 0.35343 0.07381 +D 0.42901 0.35420 0.08207 +P 0.42161 0.35639 0.08409 +A 0.41303 0.34579 0.08603 +A 0.38886 0.33013 0.08340 +L 0.34812 0.31386 0.07788 +T 0.29980 0.30414 0.06868 +A 0.26868 0.29321 0.06052 +L 0.23364 0.27896 0.04970 +H 0.22051 0.25973 0.04186 +A 0.23179 0.24984 0.04851 +R 0.23335 0.23713 0.04890 +V 0.23162 0.23371 0.04440 +D 0.25172 0.23958 0.03977 +V 0.29044 0.25186 0.03719 +L 0.32483 0.26622 0.03225 +R 0.36610 0.28707 0.03788 +R 0.41130 0.29881 0.04803 +E 0.44232 0.30062 0.05187 +S 0.49536 0.30071 0.05784 +G 0.54118 0.29716 0.06338 +V 0.57639 0.28954 0.06785 +F 0.59867 0.27496 0.06991 +E 0.60107 0.25610 0.07203 +M 0.58099 0.23012 0.07068 +D 0.53322 0.20945 0.06851 +G 0.47399 0.18955 0.06335 +F 0.42114 0.16455 0.05773 +A 0.36013 0.16009 0.04874 +D 0.30490 0.15986 0.03905 +D 0.25029 0.15580 0.03139 +F 0.19807 0.17233 0.02569 +G 0.15216 0.17909 0.02706 +A 0.10813 0.18638 0.02258 +L 0.07925 0.21160 0.01748 +L 0.06858 0.24220 0.00433 +Q 0.08658 0.25566 0.01655 +A 0.10672 0.27463 0.02276 +L 0.12623 0.30079 0.02695 +A 0.15601 0.33414 0.04016 +R 0.15847 0.42641 0.02400 +R 0.24695 0.44230 0.05018 +H 0.33573 0.35631 0.07730 +G 0.54682 0.34422 0.25423 +W 0.36015 0.55044 0.05833 +L 0.47985 0.62475 0.12977 +G 0.69681 0.58187 0.22957 +I 0.79530 0.62112 0.21132 +# RESIDUE COILS REM465 HOTLOOPS +M 0.79892 0.92921 0.40349 +G 0.74423 0.81900 0.43658 +D 0.60842 0.82833 0.08939 +T 0.56609 0.75046 0.16294 +T 0.41547 0.66867 0.10656 +A 0.51055 0.67863 0.13553 +G 0.26586 0.62069 0.02838 +E 0.28016 0.66860 0.07984 +M 0.24572 0.57265 0.03040 +A 0.22255 0.54504 0.02639 +V 0.21635 0.52145 0.04038 +Q 0.21690 0.49944 0.03196 +R 0.23267 0.49259 0.03377 +G 0.24055 0.47293 0.03344 +L 0.26254 0.46643 0.03835 +A 0.26420 0.46640 0.03487 +L 0.26992 0.46901 0.03649 +H 0.26850 0.47559 0.03522 +Q 0.25527 0.49484 0.03185 +Q 0.24162 0.49611 0.02721 +R 0.20784 0.50172 0.02291 +H 0.18286 0.48178 0.01972 +A 0.15578 0.46002 0.01334 +E 0.14728 0.43253 0.01101 +A 0.13705 0.43489 0.01111 +A 0.13657 0.42917 0.01404 +V 0.16021 0.41154 0.01697 +L 0.19843 0.40639 0.02186 +L 0.25843 0.42716 0.02856 +Q 0.32025 0.44904 0.03422 +Q 0.39430 0.47343 0.04065 +A 0.46536 0.50341 0.04688 +S 0.54129 0.51709 0.05287 +D 0.60382 0.52582 0.05727 +A 0.64679 0.52530 0.05959 +A 0.66685 0.50589 0.05977 +P 0.65775 0.47456 0.05758 +E 0.61771 0.43295 0.05223 +H 0.55706 0.38420 0.04516 +P 0.49031 0.32019 0.04045 +G 0.42702 0.26643 0.03560 +I 0.37679 0.19749 0.03172 +A 0.32669 0.15611 0.02757 +L 0.27873 0.14734 0.02398 +W 0.25091 0.14955 0.02147 +L 0.23802 0.16403 0.02028 +H 0.24701 0.17079 0.02121 +A 0.25234 0.21273 0.02182 +L 0.26130 0.25656 0.02240 +E 0.26431 0.31278 0.02254 +D 0.25736 0.37006 0.02163 +A 0.24314 0.41915 0.01983 +G 0.22595 0.44507 0.01858 +Q 0.19947 0.47713 0.01644 +A 0.18363 0.51138 0.01469 +E 0.17932 0.51322 0.01509 +A 0.17237 0.50800 0.01518 +A 0.17338 0.49921 0.01566 +A 0.17388 0.49185 0.01698 +A 0.16234 0.46450 0.01724 +Y 0.18601 0.43144 0.02005 +T 0.23484 0.39530 0.02366 +R 0.29684 0.35448 0.02975 +A 0.37098 0.33164 0.03642 +H 0.43798 0.30125 0.04196 +Q 0.50189 0.28279 0.04716 +L 0.55983 0.26400 0.05140 +L 0.60053 0.24016 0.05413 +P 0.61580 0.21851 0.05501 +E 0.60399 0.22079 0.05307 +E 0.57819 0.22202 0.04989 +P 0.53272 0.20311 0.04573 +Y 0.46895 0.19427 0.04013 +I 0.39975 0.19714 0.03277 +T 0.32217 0.19799 0.02772 +A 0.24217 0.21072 0.02151 +Q 0.19856 0.22196 0.01778 +L 0.17882 0.23839 0.01623 +L 0.18015 0.25589 0.01784 +N 0.22099 0.27406 0.02208 +A 0.25886 0.28484 0.02582 +V 0.31229 0.29687 0.03081 +A 0.37329 0.30590 0.03585 +Q 0.41602 0.30036 0.03936 +G 0.44183 0.28467 0.04120 +V 0.47255 0.26943 0.04294 +G 0.49950 0.24672 0.04205 +A 0.52528 0.21836 0.04445 +V 0.52758 0.20546 0.04013 +E 0.52887 0.20662 0.04328 +P 0.52788 0.20814 0.04978 +F 0.52478 0.20575 0.05299 +A 0.51830 0.21316 0.05248 +F 0.51521 0.23772 0.05631 +L 0.51271 0.28019 0.05970 +S 0.51824 0.34046 0.05662 +E 0.51042 0.40157 0.06786 +D 0.50605 0.45548 0.07396 +A 0.51565 0.50970 0.08190 +S 0.51314 0.52265 0.08760 +A 0.51350 0.54811 0.09539 +A 0.53026 0.56442 0.09821 +E 0.54403 0.57520 0.10208 +S 0.57221 0.57416 0.10983 +V 0.57841 0.57213 0.10431 +R 0.60075 0.54032 0.09786 +P 0.62011 0.51067 0.11639 +L 0.63932 0.46748 0.12785 +A 0.64699 0.43929 0.13600 +P 0.65559 0.41463 0.14158 +T 0.67237 0.41278 0.14389 +R 0.68444 0.41621 0.14370 +V 0.68674 0.40699 0.15192 +R 0.69802 0.38662 0.14650 +S 0.69242 0.36595 0.14032 +K 0.66442 0.32203 0.12958 +G 0.63516 0.30503 0.11619 +P 0.61231 0.27691 0.09939 +L 0.58285 0.26232 0.08426 +R 0.57239 0.24178 0.06952 +V 0.55583 0.21093 0.04775 +G 0.54798 0.18271 0.03550 +F 0.54729 0.18625 0.05813 +V 0.56353 0.19115 0.06508 +S 0.58514 0.20302 0.07226 +N 0.61899 0.21760 0.07689 +G 0.64417 0.24094 0.08339 +F 0.66852 0.25410 0.08740 +G 0.67113 0.26439 0.08673 +A 0.65329 0.26395 0.08359 +H 0.59906 0.25471 0.07593 +P 0.53852 0.23852 0.06676 +T 0.46756 0.23838 0.05520 +G 0.39638 0.22887 0.04532 +L 0.32435 0.21985 0.03424 +L 0.25959 0.20622 0.02455 +T 0.21092 0.19002 0.01454 +V 0.16286 0.18984 0.00874 +A 0.13222 0.19663 0.01040 +L 0.13718 0.21327 0.01176 +F 0.15922 0.22668 0.01421 +E 0.19287 0.25014 0.01571 +A 0.24795 0.27481 0.02231 +L 0.30912 0.29319 0.02781 +Q 0.36600 0.31761 0.03436 +R 0.40904 0.32357 0.04039 +R 0.44641 0.31944 0.04550 +Q 0.47387 0.31066 0.04911 +P 0.48015 0.30088 0.05001 +D 0.46585 0.27977 0.04718 +L 0.43848 0.26224 0.04029 +Q 0.41204 0.24283 0.03653 +M 0.40286 0.22376 0.03416 +H 0.38445 0.22935 0.04559 +L 0.40616 0.24686 0.05506 +F 0.44756 0.28038 0.07106 +A 0.47610 0.30637 0.08409 +T 0.52735 0.35044 0.09517 +S 0.56587 0.38896 0.10535 +G 0.57757 0.43154 0.10837 +D 0.58300 0.46681 0.10980 +D 0.55714 0.47586 0.10507 +G 0.52225 0.46343 0.09636 +S 0.49037 0.44504 0.08443 +T 0.44095 0.43528 0.06889 +L 0.37153 0.42133 0.04888 +R 0.31143 0.39708 0.03105 +T 0.27726 0.37781 0.01676 +R 0.27155 0.36109 0.01414 +L 0.28212 0.36818 0.02699 +A 0.32672 0.37349 0.03457 +Q 0.37520 0.37718 0.04759 +A 0.40565 0.37791 0.05522 +S 0.43709 0.38006 0.06145 +T 0.42865 0.37978 0.06213 +L 0.42653 0.37779 0.06203 +H 0.41799 0.35467 0.06181 +D 0.40044 0.33312 0.05776 +V 0.40150 0.31093 0.05556 +T 0.41246 0.30646 0.05349 +A 0.40495 0.29640 0.05083 +L 0.38425 0.29841 0.04063 +G 0.37341 0.31172 0.03907 +H 0.37246 0.32334 0.03285 +L 0.38933 0.33516 0.04222 +A 0.38737 0.36073 0.05225 +T 0.39737 0.37986 0.06044 +A 0.39716 0.39982 0.06460 +K 0.37829 0.40866 0.06597 +H 0.35046 0.39889 0.06465 +I 0.32903 0.38932 0.06095 +R 0.31342 0.37365 0.05668 +H 0.28853 0.35140 0.05380 +H 0.27629 0.33450 0.04777 +G 0.29822 0.30711 0.04648 +I 0.31666 0.28368 0.04202 +D 0.33323 0.24918 0.03960 +L 0.35823 0.24361 0.03424 +L 0.39797 0.22750 0.04012 +F 0.44639 0.21384 0.04190 +D 0.50116 0.22639 0.05091 +L 0.55514 0.24972 0.05808 +R 0.61133 0.27218 0.06250 +G 0.66599 0.28765 0.06599 +W 0.70960 0.29860 0.06791 +G 0.73011 0.30278 0.06742 +G 0.72946 0.30915 0.06371 +G 0.71108 0.30904 0.06168 +G 0.68003 0.30934 0.05571 +R 0.66061 0.29289 0.04656 +P 0.64635 0.27540 0.05550 +E 0.62499 0.25806 0.06154 +V 0.62287 0.23817 0.06756 +F 0.61060 0.22593 0.07470 +A 0.59656 0.21864 0.08205 +L 0.60330 0.21961 0.08723 +R 0.62421 0.23110 0.09194 +P 0.63973 0.23597 0.09437 +A 0.63254 0.24152 0.09269 +P 0.63711 0.23203 0.08998 +V 0.62232 0.23166 0.08314 +Q 0.60255 0.21849 0.07443 +V 0.59309 0.19996 0.06600 +N 0.59586 0.18959 0.05853 +W 0.59987 0.19889 0.04827 +L 0.61528 0.19585 0.04572 +A 0.65515 0.21571 0.05698 +Y 0.69371 0.23266 0.05857 +P 0.73439 0.25305 0.06008 +G 0.74188 0.26312 0.06422 +T 0.75123 0.27052 0.06498 +S 0.76951 0.26451 0.06622 +G 0.76779 0.25325 0.06613 +A 0.72111 0.23147 0.06174 +P 0.67480 0.21248 0.05747 +W 0.62753 0.18266 0.05294 +M 0.56914 0.15468 0.04739 +D 0.51707 0.12451 0.04297 +Y 0.48676 0.10065 0.04061 +V 0.46016 0.10000 0.03796 +L 0.45125 0.09899 0.03673 +G 0.46512 0.11515 0.03756 +D 0.49575 0.13961 0.03981 +A 0.52466 0.15857 0.04193 +F 0.57603 0.17730 0.04653 +A 0.62643 0.18387 0.05093 +L 0.66695 0.17936 0.05452 +P 0.71435 0.19585 0.05745 +P 0.73410 0.21047 0.05962 +A 0.73013 0.21125 0.06018 +L 0.72402 0.22164 0.06056 +E 0.69564 0.22568 0.05896 +P 0.63984 0.23915 0.05487 +F 0.58543 0.24806 0.05085 +Y 0.52763 0.26149 0.04642 +S 0.44437 0.27688 0.03734 +E 0.38994 0.28580 0.03378 +H 0.35698 0.32239 0.03272 +V 0.33694 0.33489 0.03170 +L 0.34704 0.33592 0.03225 +R 0.38340 0.34142 0.03633 +L 0.42595 0.35345 0.04216 +Q 0.47377 0.35116 0.04156 +G 0.54491 0.39114 0.05373 +A 0.59484 0.41648 0.06565 +F 0.64512 0.44408 0.07508 +Q 0.68398 0.47392 0.08236 +P 0.71015 0.50429 0.08796 +S 0.72130 0.54316 0.08945 +D 0.74023 0.56084 0.08986 +T 0.73744 0.58262 0.08960 +S 0.72650 0.59894 0.08635 +R 0.73237 0.61200 0.08672 +V 0.74400 0.63068 0.08153 +V 0.74773 0.62745 0.07749 +A 0.76058 0.62126 0.07520 +E 0.76800 0.60970 0.07795 +P 0.77430 0.59118 0.07922 +P 0.78245 0.55519 0.07148 +S 0.80137 0.54121 0.08379 +R 0.81007 0.51724 0.09656 +T 0.81403 0.49308 0.10518 +Q 0.80079 0.45171 0.11149 +C 0.78528 0.41673 0.11452 +G 0.76190 0.37530 0.11100 +L 0.71814 0.32633 0.10722 +P 0.67495 0.28305 0.10562 +E 0.62661 0.24178 0.09856 +Q 0.56985 0.20651 0.08806 +G 0.52558 0.17933 0.07590 +V 0.47230 0.15205 0.06666 +V 0.43535 0.13419 0.05794 +L 0.40715 0.11369 0.05152 +C 0.41016 0.10273 0.04279 +C 0.43433 0.09879 0.03559 +F 0.50619 0.10500 0.04489 +N 0.57712 0.12335 0.05514 +N 0.62439 0.14604 0.05781 +S 0.63807 0.18419 0.05701 +Y 0.64582 0.21583 0.05612 +K 0.62340 0.24793 0.05276 +L 0.57371 0.28206 0.05093 +N 0.52540 0.29710 0.04927 +P 0.45482 0.31328 0.04325 +Q 0.37909 0.31568 0.03689 +S 0.29692 0.30541 0.02973 +M 0.21762 0.29356 0.02260 +A 0.15041 0.26998 0.01661 +R 0.09545 0.24528 0.01214 +M 0.08442 0.22763 0.01056 +L 0.11346 0.21969 0.01251 +A 0.16837 0.21275 0.01654 +V 0.22297 0.21879 0.02025 +L 0.26784 0.22602 0.02408 +R 0.30242 0.24476 0.02673 +E 0.33874 0.25182 0.03097 +V 0.34959 0.27168 0.03150 +P 0.33978 0.27434 0.03121 +D 0.33332 0.27763 0.03094 +S 0.32976 0.29445 0.03047 +V 0.35623 0.29670 0.03296 +L 0.37151 0.28190 0.03391 +W 0.39865 0.29676 0.03479 +L 0.41861 0.30967 0.03663 +L 0.43481 0.32817 0.03818 +S 0.45442 0.35277 0.04037 +G 0.46433 0.36330 0.04162 +P 0.46649 0.36202 0.04203 +G 0.46746 0.36549 0.04237 +E 0.44268 0.35150 0.04112 +A 0.39880 0.34825 0.03745 +D 0.34362 0.33941 0.03023 +A 0.27079 0.32740 0.02553 +R 0.19685 0.30861 0.02129 +L 0.15646 0.30589 0.01928 +R 0.14567 0.30763 0.01266 +A 0.17408 0.31707 0.01691 +F 0.21654 0.33503 0.02252 +A 0.26349 0.38717 0.03069 +H 0.32359 0.41084 0.04191 +A 0.38144 0.41639 0.05518 +Q 0.43067 0.42053 0.06218 +G 0.47270 0.40240 0.07489 +V 0.50814 0.38341 0.08407 +D 0.52289 0.35372 0.08916 +A 0.53947 0.31127 0.09208 +Q 0.55178 0.27810 0.09175 +R 0.56301 0.23283 0.08799 +L 0.57426 0.19651 0.08755 +V 0.59531 0.17737 0.08383 +F 0.60326 0.15396 0.07657 +M 0.62804 0.16806 0.06773 +P 0.65584 0.19021 0.06801 +K 0.68140 0.21968 0.06499 +L 0.68264 0.23978 0.06242 +P 0.68490 0.24644 0.06013 +H 0.68668 0.26272 0.05960 +P 0.67935 0.27414 0.05542 +Q 0.64507 0.26988 0.05695 +Y 0.60140 0.26219 0.05228 +L 0.56330 0.24327 0.04858 +A 0.55438 0.22917 0.04645 +R 0.52210 0.21007 0.04306 +Y 0.51021 0.18991 0.04170 +R 0.50118 0.17798 0.03976 +H 0.49408 0.17028 0.04134 +A 0.49113 0.14885 0.04276 +D 0.52093 0.14786 0.04658 +L 0.54598 0.14366 0.04963 +F 0.57162 0.15295 0.05237 +L 0.59979 0.15882 0.05418 +D 0.62941 0.18150 0.05724 +T 0.66631 0.19936 0.05978 +H 0.69373 0.21439 0.06162 +P 0.70792 0.24334 0.06451 +Y 0.73006 0.28913 0.06664 +N 0.73659 0.31948 0.05917 +A 0.74324 0.35862 0.06255 +H 0.69816 0.38328 0.06584 +T 0.66515 0.40185 0.07276 +T 0.61727 0.40648 0.07578 +A 0.59280 0.40090 0.08299 +S 0.58091 0.37470 0.08683 +D 0.58233 0.35162 0.08915 +A 0.59138 0.32705 0.09026 +L 0.59940 0.29487 0.08907 +W 0.61086 0.25952 0.08583 +T 0.63117 0.23415 0.08354 +G 0.64088 0.20701 0.07736 +C 0.66172 0.19254 0.07067 +P 0.69118 0.20234 0.06654 +V 0.70553 0.22105 0.05918 +L 0.70208 0.22639 0.05011 +T 0.68245 0.24682 0.05419 +T 0.62544 0.25800 0.05278 +P 0.56988 0.27315 0.05171 +G 0.51318 0.28596 0.04768 +E 0.46788 0.29210 0.04443 +T 0.41726 0.29146 0.04050 +F 0.36734 0.29524 0.03603 +A 0.32063 0.28693 0.03220 +A 0.26832 0.28731 0.02700 +R 0.24681 0.28867 0.02490 +V 0.24436 0.29256 0.02440 +A 0.24656 0.29313 0.02350 +G 0.27373 0.28458 0.02360 +S 0.32678 0.28414 0.02955 +L 0.37613 0.28419 0.03492 +N 0.42874 0.27040 0.03982 +H 0.47657 0.25552 0.04416 +H 0.53361 0.24348 0.04881 +L 0.56876 0.23408 0.05143 +G 0.59975 0.22377 0.05394 +L 0.61704 0.21744 0.05507 +D 0.62577 0.21108 0.05533 +E 0.61075 0.20183 0.05320 +M 0.58173 0.20394 0.05023 +N 0.53686 0.21602 0.04574 +V 0.49281 0.21370 0.04199 +A 0.42644 0.21815 0.03603 +D 0.36426 0.22473 0.03003 +D 0.30930 0.22202 0.02475 +A 0.26382 0.22207 0.02141 +A 0.20346 0.22812 0.01511 +F 0.16652 0.23306 0.01146 +V 0.13737 0.25019 0.00886 +A 0.12949 0.26687 0.00225 +K 0.15808 0.27795 0.01186 +A 0.21339 0.29573 0.02783 +V 0.26353 0.31670 0.04126 +A 0.31427 0.32406 0.05199 +L 0.36375 0.33586 0.06233 +A 0.39713 0.35160 0.06954 +S 0.41552 0.35343 0.07381 +D 0.42901 0.35420 0.08207 +P 0.42161 0.35639 0.08409 +A 0.41303 0.34579 0.08603 +A 0.38886 0.33013 0.08340 +L 0.34812 0.31386 0.07788 +T 0.29980 0.30414 0.06868 +A 0.26868 0.29321 0.06052 +L 0.23364 0.27896 0.04970 +H 0.22051 0.25973 0.04186 +A 0.23179 0.24984 0.04851 +R 0.23335 0.23713 0.04890 +V 0.23162 0.23371 0.04440 +D 0.25172 0.23958 0.03977 +V 0.29044 0.25186 0.03719 +L 0.32483 0.26622 0.03225 +R 0.36610 0.28707 0.03788 +R 0.41130 0.29881 0.04803 +E 0.44232 0.30062 0.05187 +S 0.49536 0.30071 0.05784 +G 0.54118 0.29716 0.06338 +V 0.57639 0.28954 0.06785 +F 0.59867 0.27496 0.06991 +E 0.60107 0.25610 0.07203 +M 0.58099 0.23012 0.07068 +D 0.53322 0.20945 0.06851 +G 0.47399 0.18955 0.06335 +F 0.42114 0.16455 0.05773 +A 0.36013 0.16009 0.04874 +D 0.30490 0.15986 0.03905 +D 0.25029 0.15580 0.03139 +F 0.19807 0.17233 0.02569 +G 0.15216 0.17909 0.02706 +A 0.10813 0.18638 0.02258 +L 0.07925 0.21160 0.01748 +L 0.06858 0.24220 0.00433 +Q 0.08658 0.25566 0.01655 +A 0.10672 0.27463 0.02276 +L 0.12623 0.30079 0.02695 +A 0.15601 0.33414 0.04016 +R 0.15847 0.42641 0.02400 +R 0.24695 0.44230 0.05018 +H 0.33573 0.35631 0.07730 +G 0.54682 0.34422 0.25423 +W 0.36015 0.55044 0.05833 +L 0.47985 0.62475 0.12977 +G 0.69681 0.58187 0.22957 +I 0.79530 0.62112 0.21132 +# RESIDUE COILS REM465 HOTLOOPS +M 0.86010 0.88512 0.37094 +T 0.79983 0.85864 0.44331 +A 0.72031 0.83329 0.43668 +D 0.62168 0.79393 0.27484 +G 0.50983 0.59080 0.08453 +P 0.25998 0.36247 0.07824 +R 0.29879 0.44037 0.06849 +E 0.25286 0.32959 0.04415 +L 0.20943 0.31797 0.04618 +L 0.17624 0.28671 0.01931 +Q 0.15219 0.27288 0.01291 +L 0.17077 0.27141 0.04418 +R 0.20773 0.29874 0.07215 +A 0.24652 0.32640 0.08449 +A 0.27945 0.33948 0.09399 +V 0.31413 0.35494 0.09834 +R 0.34058 0.35621 0.10360 +H 0.35819 0.36011 0.10861 +R 0.36170 0.35006 0.10579 +P 0.35340 0.32859 0.09729 +Q 0.33982 0.30310 0.09009 +D 0.31390 0.25550 0.07910 +V 0.29248 0.20603 0.06265 +A 0.25978 0.18203 0.04295 +W 0.23700 0.16252 0.03059 +L 0.20659 0.15437 0.01799 +M 0.19746 0.16052 0.01739 +L 0.22270 0.16616 0.03081 +A 0.26055 0.19292 0.03190 +D 0.30598 0.20791 0.03292 +A 0.36133 0.22227 0.03452 +E 0.41353 0.24276 0.03721 +L 0.48565 0.27072 0.04690 +G 0.53935 0.30076 0.05086 +M 0.57647 0.32767 0.05319 +G 0.58650 0.35718 0.05304 +D 0.57401 0.39529 0.05115 +T 0.54811 0.40315 0.04712 +T 0.49998 0.41707 0.04147 +A 0.44247 0.42420 0.03617 +G 0.38488 0.42355 0.03242 +E 0.32062 0.43459 0.02860 +M 0.27621 0.43599 0.02383 +A 0.24947 0.43579 0.02310 +V 0.26104 0.44630 0.02454 +Q 0.28555 0.42657 0.03013 +R 0.33863 0.41808 0.03695 +G 0.42083 0.41277 0.04739 +L 0.52012 0.40903 0.05934 +A 0.57192 0.40310 0.06618 +L 0.61014 0.39172 0.07155 +H 0.62000 0.38603 0.07143 +P 0.61420 0.38863 0.07132 +G 0.59027 0.36809 0.06880 +H 0.54439 0.37383 0.06386 +P 0.50222 0.36429 0.05768 +E 0.45498 0.35329 0.05279 +A 0.40408 0.33619 0.04550 +V 0.36729 0.33364 0.03718 +A 0.33908 0.34380 0.03627 +R 0.34141 0.35219 0.03640 +L 0.35060 0.35611 0.03942 +G 0.37329 0.36835 0.04165 +R 0.39930 0.37477 0.04556 +V 0.41249 0.38955 0.04707 +R 0.40000 0.39924 0.04544 +W 0.38778 0.41158 0.04330 +T 0.36202 0.43951 0.03890 +Q 0.32894 0.45950 0.03453 +Q 0.29139 0.46461 0.03096 +R 0.24944 0.47555 0.02594 +H 0.22078 0.46457 0.02235 +A 0.18668 0.44830 0.01686 +E 0.15893 0.41673 0.01509 +A 0.13593 0.41862 0.01574 +A 0.13590 0.41297 0.02226 +V 0.16183 0.39515 0.02744 +L 0.19353 0.40028 0.03432 +L 0.24663 0.40988 0.04185 +Q 0.31725 0.43753 0.04970 +Q 0.38948 0.45652 0.05601 +A 0.46684 0.49088 0.06182 +S 0.54056 0.51927 0.06564 +D 0.60106 0.54082 0.06724 +A 0.64620 0.53373 0.06663 +A 0.66884 0.51613 0.06630 +P 0.65928 0.48452 0.06126 +E 0.61097 0.44778 0.05391 +H 0.54571 0.39597 0.04478 +P 0.48380 0.33950 0.03971 +G 0.42532 0.29589 0.03490 +I 0.38661 0.24310 0.03176 +A 0.33624 0.19820 0.02728 +L 0.31498 0.19356 0.02728 +W 0.31509 0.18916 0.02744 +L 0.32331 0.19389 0.02797 +G 0.34600 0.19443 0.02982 +H 0.39377 0.21353 0.03372 +A 0.45252 0.22923 0.03818 +L 0.51886 0.24951 0.04346 +E 0.57539 0.25676 0.04810 +D 0.63234 0.26350 0.05252 +H 0.66654 0.25873 0.05491 +Q 0.69000 0.25600 0.05661 +L 0.72697 0.23892 0.05926 +L 0.73889 0.23497 0.06031 +P 0.72907 0.23147 0.05950 +E 0.69616 0.23346 0.05658 +E 0.64188 0.22949 0.05192 +P 0.59731 0.24316 0.04866 +Y 0.53010 0.23475 0.04373 +I 0.45703 0.24154 0.03800 +T 0.39436 0.24885 0.03356 +A 0.33742 0.25605 0.02930 +Q 0.28694 0.27691 0.02498 +L 0.25054 0.29481 0.02221 +D 0.22341 0.31236 0.02035 +V 0.21482 0.33354 0.01998 +L 0.20065 0.36268 0.01701 +S 0.20526 0.38583 0.01910 +A 0.19260 0.41144 0.01877 +Q 0.16815 0.43924 0.01736 +V 0.16434 0.45274 0.01846 +R 0.17026 0.45505 0.01889 +A 0.20301 0.45055 0.02301 +A 0.23514 0.45000 0.02681 +V 0.26802 0.41894 0.03061 +A 0.31174 0.40011 0.03490 +Q 0.35250 0.36345 0.03870 +G 0.38178 0.32249 0.04062 +V 0.42079 0.29097 0.04295 +G 0.45491 0.26034 0.04537 +A 0.49886 0.22657 0.04895 +V 0.52391 0.20562 0.05130 +E 0.53303 0.20165 0.05126 +P 0.53975 0.20063 0.05403 +F 0.52385 0.20385 0.05161 +A 0.50639 0.22752 0.04984 +F 0.48741 0.26114 0.04846 +L 0.46674 0.28999 0.04597 +S 0.43909 0.33263 0.04400 +E 0.39696 0.36707 0.03985 +D 0.35208 0.41809 0.03509 +A 0.30408 0.46253 0.03007 +S 0.24901 0.46649 0.02454 +A 0.19867 0.47834 0.01929 +A 0.16075 0.50072 0.01365 +E 0.13788 0.50748 0.01122 +Q 0.13506 0.50876 0.01368 +L 0.12169 0.51337 0.01547 +A 0.12136 0.51136 0.01598 +C 0.13259 0.50633 0.01649 +A 0.13448 0.48088 0.01786 +R 0.13417 0.48245 0.02171 +T 0.14810 0.47380 0.02092 +R 0.15594 0.46796 0.02898 +A 0.16180 0.47356 0.03389 +Q 0.19117 0.47436 0.04219 +A 0.22511 0.46346 0.05995 +I 0.26575 0.46364 0.06867 +A 0.31723 0.44786 0.08230 +A 0.37505 0.45856 0.10196 +S 0.43341 0.46499 0.12734 +V 0.50181 0.46517 0.14401 +R 0.55621 0.45469 0.15645 +P 0.60375 0.45290 0.17581 +L 0.64486 0.44417 0.18570 +A 0.66990 0.43379 0.19070 +P 0.68382 0.41168 0.18878 +T 0.70233 0.41020 0.18048 +R 0.72070 0.40484 0.16987 +V 0.71180 0.39972 0.16069 +R 0.71532 0.37964 0.14413 +S 0.70293 0.35656 0.12867 +K 0.67155 0.32107 0.11402 +G 0.63844 0.31759 0.08838 +P 0.61151 0.28482 0.07748 +L 0.58165 0.26357 0.07057 +R 0.56607 0.23944 0.06683 +V 0.55583 0.20985 0.05244 +G 0.54798 0.18271 0.04783 +F 0.54729 0.18625 0.06066 +V 0.56353 0.19115 0.06687 +S 0.58514 0.20302 0.07328 +N 0.61899 0.21760 0.07727 +G 0.64417 0.24094 0.08164 +F 0.66852 0.25410 0.08724 +G 0.67113 0.26439 0.08635 +A 0.65329 0.26395 0.08354 +H 0.59906 0.25471 0.07613 +P 0.53852 0.23852 0.06676 +T 0.46756 0.23838 0.05520 +G 0.39638 0.22887 0.04532 +L 0.32435 0.21985 0.03424 +L 0.25959 0.20622 0.02455 +T 0.21092 0.19002 0.01454 +V 0.16286 0.18984 0.00874 +A 0.13222 0.19663 0.01040 +L 0.13718 0.21327 0.01176 +F 0.15922 0.22668 0.01421 +E 0.19287 0.25014 0.01571 +A 0.24795 0.27481 0.02231 +L 0.30912 0.29319 0.02781 +Q 0.36600 0.31761 0.03436 +R 0.40904 0.32357 0.04039 +R 0.44641 0.31944 0.04550 +Q 0.47387 0.31066 0.04911 +P 0.48015 0.30088 0.05001 +D 0.46585 0.27977 0.04718 +L 0.43848 0.26224 0.04029 +Q 0.41204 0.24283 0.03653 +M 0.40286 0.22376 0.03416 +H 0.38445 0.22935 0.04559 +L 0.40616 0.24686 0.05506 +F 0.44756 0.28038 0.07106 +A 0.47610 0.30637 0.08409 +T 0.52735 0.35044 0.09517 +S 0.56587 0.38896 0.10535 +G 0.57757 0.43154 0.10837 +D 0.58300 0.46681 0.10980 +D 0.55714 0.47586 0.10507 +G 0.52225 0.46343 0.09636 +S 0.49037 0.44504 0.08443 +T 0.44095 0.43528 0.06889 +L 0.37153 0.42133 0.04888 +R 0.31143 0.39708 0.03105 +T 0.27726 0.37781 0.01676 +R 0.27155 0.36109 0.01414 +L 0.28212 0.36818 0.02699 +A 0.32672 0.37349 0.03457 +Q 0.37520 0.37718 0.04759 +A 0.40565 0.37791 0.05522 +S 0.43709 0.38006 0.06145 +T 0.42865 0.37978 0.06213 +L 0.42653 0.37779 0.06203 +H 0.41799 0.35467 0.06181 +D 0.40044 0.33312 0.05776 +V 0.40150 0.31093 0.05556 +T 0.41246 0.30646 0.05349 +A 0.40495 0.29640 0.05083 +L 0.38425 0.29841 0.04063 +G 0.37341 0.31172 0.03907 +H 0.37246 0.32334 0.03285 +L 0.38933 0.33516 0.04222 +A 0.38737 0.36073 0.05225 +T 0.39737 0.37986 0.06044 +A 0.39716 0.39982 0.06460 +K 0.37829 0.40866 0.06597 +H 0.35046 0.39889 0.06465 +I 0.32903 0.38932 0.06095 +R 0.31342 0.37365 0.05668 +H 0.28853 0.35140 0.05380 +H 0.27629 0.33450 0.04777 +G 0.29822 0.30711 0.04648 +I 0.31666 0.28368 0.04202 +D 0.33323 0.24918 0.03960 +L 0.35823 0.24361 0.03424 +L 0.39797 0.22750 0.04012 +F 0.44639 0.21384 0.04190 +D 0.50116 0.22639 0.05091 +L 0.55514 0.24972 0.05808 +R 0.61133 0.27218 0.06250 +G 0.66599 0.28765 0.06599 +W 0.70960 0.29860 0.06791 +G 0.73011 0.30278 0.06742 +G 0.72946 0.30915 0.06371 +G 0.71108 0.30904 0.06168 +G 0.68003 0.30934 0.05571 +R 0.66061 0.29289 0.04656 +P 0.64635 0.27540 0.05550 +E 0.62499 0.25806 0.06154 +V 0.62287 0.23817 0.06756 +F 0.61060 0.22593 0.07470 +A 0.59656 0.21864 0.08205 +L 0.60330 0.21961 0.08723 +R 0.62421 0.23110 0.09194 +P 0.63973 0.23597 0.09437 +A 0.63254 0.24152 0.09269 +P 0.63711 0.23203 0.08998 +V 0.62232 0.23166 0.08314 +Q 0.60255 0.21849 0.07443 +V 0.59309 0.19996 0.06600 +N 0.59586 0.18959 0.05853 +W 0.59987 0.19889 0.04827 +L 0.61528 0.19585 0.04572 +A 0.65515 0.21571 0.05698 +Y 0.69371 0.23266 0.05857 +P 0.73439 0.25305 0.06008 +G 0.74188 0.26312 0.06422 +T 0.75123 0.27052 0.06498 +S 0.76951 0.26451 0.06622 +G 0.76779 0.25325 0.06613 +A 0.72111 0.23147 0.06174 +P 0.67480 0.21248 0.05747 +W 0.62753 0.18266 0.05294 +M 0.56914 0.15468 0.04739 +D 0.51707 0.12451 0.04297 +Y 0.48676 0.10065 0.04061 +V 0.46016 0.10000 0.03796 +L 0.45125 0.09899 0.03673 +G 0.46512 0.11515 0.03756 +D 0.49575 0.13961 0.03981 +A 0.52466 0.15857 0.04193 +F 0.57603 0.17730 0.04653 +A 0.62643 0.18387 0.05093 +L 0.66695 0.17936 0.05452 +P 0.71435 0.19585 0.05745 +P 0.73410 0.21047 0.05962 +A 0.73013 0.21125 0.06018 +L 0.72402 0.22164 0.06056 +E 0.69564 0.22568 0.05896 +P 0.63984 0.23915 0.05487 +F 0.58543 0.24806 0.05085 +Y 0.52763 0.26149 0.04642 +S 0.44437 0.27688 0.03734 +E 0.38994 0.28580 0.03378 +H 0.35698 0.32239 0.03272 +V 0.33694 0.33489 0.03170 +L 0.34704 0.33592 0.03225 +R 0.38340 0.34142 0.03633 +L 0.42595 0.35345 0.04216 +Q 0.47377 0.35116 0.04156 +G 0.54491 0.39114 0.05373 +A 0.59484 0.41648 0.06565 +F 0.64512 0.44408 0.07508 +Q 0.68398 0.47392 0.08236 +P 0.71015 0.50429 0.08796 +S 0.72130 0.54316 0.08945 +D 0.74023 0.56084 0.08986 +T 0.73744 0.58262 0.08960 +S 0.72650 0.59894 0.08635 +R 0.73237 0.61200 0.08672 +V 0.74400 0.63068 0.08153 +V 0.74773 0.62745 0.07749 +A 0.76058 0.62126 0.07520 +E 0.76800 0.60970 0.07795 +P 0.77430 0.59118 0.07922 +P 0.78245 0.55519 0.07148 +S 0.80137 0.54121 0.08379 +R 0.81007 0.51724 0.09656 +T 0.81403 0.49308 0.10518 +Q 0.80079 0.45171 0.11149 +C 0.78528 0.41673 0.11452 +G 0.76190 0.37530 0.11100 +L 0.71814 0.32633 0.10722 +P 0.67495 0.28305 0.10562 +E 0.62661 0.24178 0.09856 +Q 0.56985 0.20651 0.08806 +G 0.52558 0.17933 0.07590 +V 0.47230 0.15205 0.06666 +V 0.43535 0.13419 0.05794 +L 0.40715 0.11369 0.05152 +C 0.41016 0.10273 0.04279 +C 0.43433 0.09879 0.03559 +F 0.50619 0.10500 0.04489 +N 0.57712 0.12335 0.05514 +N 0.62439 0.14604 0.05781 +S 0.63807 0.18419 0.05701 +Y 0.64582 0.21583 0.05612 +K 0.62340 0.24793 0.05276 +L 0.57371 0.28206 0.05093 +N 0.52540 0.29710 0.04927 +P 0.45482 0.31328 0.04325 +Q 0.37909 0.31568 0.03689 +S 0.29692 0.30541 0.02973 +M 0.21762 0.29356 0.02260 +A 0.15041 0.26998 0.01661 +R 0.09545 0.24528 0.01214 +M 0.08442 0.22763 0.01056 +L 0.11346 0.21969 0.01251 +A 0.16837 0.21275 0.01654 +V 0.22297 0.21879 0.02025 +L 0.26784 0.22602 0.02408 +R 0.30242 0.24476 0.02673 +E 0.33874 0.25182 0.03097 +V 0.34959 0.27168 0.03150 +P 0.33978 0.27434 0.03121 +D 0.33332 0.27763 0.03094 +S 0.32976 0.29445 0.03047 +V 0.35623 0.29670 0.03296 +L 0.37151 0.28190 0.03391 +W 0.39865 0.29676 0.03479 +L 0.41861 0.30967 0.03663 +L 0.43481 0.32817 0.03818 +S 0.45442 0.35277 0.04037 +G 0.46433 0.36330 0.04162 +P 0.46649 0.36202 0.04203 +G 0.46746 0.36549 0.04237 +E 0.44268 0.35150 0.04112 +A 0.39880 0.34825 0.03745 +D 0.34362 0.33941 0.03023 +A 0.27079 0.32740 0.02553 +R 0.19685 0.30861 0.02129 +L 0.15646 0.30589 0.01928 +R 0.14567 0.30763 0.01266 +A 0.17408 0.31707 0.01691 +F 0.21654 0.33503 0.02252 +A 0.26349 0.38717 0.03069 +H 0.32359 0.41084 0.04191 +A 0.38144 0.41639 0.05518 +Q 0.43067 0.42053 0.06218 +G 0.47270 0.40240 0.07489 +V 0.50814 0.38341 0.08407 +D 0.52289 0.35372 0.08916 +A 0.53947 0.31127 0.09208 +Q 0.55178 0.27810 0.09175 +R 0.56301 0.23283 0.08799 +L 0.57426 0.19651 0.08755 +V 0.59531 0.17737 0.08383 +F 0.60326 0.15396 0.07657 +M 0.62804 0.16806 0.06773 +P 0.65584 0.19021 0.06801 +K 0.68140 0.21968 0.06499 +L 0.68264 0.23978 0.06242 +P 0.68490 0.24644 0.06013 +H 0.68668 0.26272 0.05960 +P 0.67935 0.27414 0.05542 +Q 0.64507 0.26988 0.05695 +Y 0.60140 0.26219 0.05228 +L 0.56330 0.24327 0.04858 +A 0.55438 0.22917 0.04645 +R 0.52210 0.21007 0.04306 +Y 0.51021 0.18991 0.04170 +R 0.50118 0.17798 0.03976 +H 0.49408 0.17028 0.04134 +A 0.49113 0.14885 0.04276 +D 0.52093 0.14786 0.04658 +L 0.54598 0.14366 0.04963 +F 0.57162 0.15295 0.05237 +L 0.59979 0.15882 0.05418 +D 0.62941 0.18150 0.05724 +T 0.66631 0.19936 0.05978 +H 0.69373 0.21439 0.06162 +P 0.70792 0.24334 0.06451 +Y 0.73006 0.28913 0.06664 +N 0.73659 0.31948 0.05917 +A 0.74324 0.35862 0.06255 +H 0.69816 0.38328 0.06584 +T 0.66515 0.40185 0.07276 +T 0.61727 0.40648 0.07578 +A 0.59280 0.40090 0.08299 +S 0.58091 0.37470 0.08683 +D 0.58233 0.35162 0.08915 +A 0.59138 0.32705 0.09026 +L 0.59940 0.29487 0.08907 +W 0.61086 0.25952 0.08583 +T 0.63117 0.23415 0.08354 +G 0.64088 0.20701 0.07736 +C 0.66172 0.19254 0.07067 +P 0.69118 0.20234 0.06654 +V 0.70553 0.22105 0.05918 +L 0.70208 0.22639 0.05011 +T 0.68245 0.24682 0.05419 +T 0.62544 0.25800 0.05278 +P 0.56988 0.27315 0.05171 +G 0.51318 0.28596 0.04768 +E 0.46788 0.29210 0.04443 +T 0.41726 0.29146 0.04050 +F 0.36734 0.29524 0.03603 +A 0.32063 0.28693 0.03220 +A 0.26832 0.28731 0.02700 +R 0.24681 0.28867 0.02490 +V 0.24436 0.29256 0.02440 +A 0.24656 0.29313 0.02350 +G 0.27373 0.28458 0.02360 +S 0.32678 0.28414 0.02955 +L 0.37613 0.28419 0.03492 +N 0.42874 0.27040 0.03982 +H 0.47657 0.25552 0.04416 +H 0.53361 0.24348 0.04881 +L 0.56876 0.23408 0.05143 +G 0.59975 0.22377 0.05394 +L 0.61704 0.21744 0.05507 +D 0.62577 0.21108 0.05533 +E 0.61075 0.20183 0.05320 +M 0.58173 0.20394 0.05023 +N 0.53686 0.21602 0.04574 +V 0.49281 0.21370 0.04199 +A 0.42644 0.21815 0.03603 +D 0.36426 0.22473 0.03003 +D 0.30930 0.22202 0.02475 +A 0.26382 0.22207 0.02141 +A 0.20346 0.22812 0.01511 +F 0.16652 0.23306 0.01146 +V 0.13737 0.25019 0.00807 +A 0.12949 0.26687 0.00000 +K 0.15808 0.27795 0.00831 +A 0.21339 0.29573 0.02806 +V 0.26353 0.31670 0.04668 +A 0.31427 0.32406 0.06213 +L 0.36375 0.33586 0.07438 +A 0.39713 0.35160 0.08328 +S 0.41552 0.35343 0.08768 +D 0.42901 0.35420 0.09377 +P 0.42161 0.35561 0.09258 +A 0.41350 0.34029 0.09738 +A 0.39008 0.32720 0.09705 +L 0.35045 0.30464 0.09564 +T 0.29152 0.29845 0.08469 +A 0.26576 0.29222 0.08055 +L 0.23026 0.29345 0.06954 +H 0.22267 0.27732 0.06684 +A 0.25403 0.27306 0.08307 +R 0.24334 0.28281 0.08723 +V 0.22491 0.30878 0.07340 +D 0.22851 0.43041 0.04704 +V 0.39251 0.34002 0.11921 +L 0.20637 0.41747 0.05445 +R 0.27441 0.38910 0.11186 +R 0.34891 0.61978 0.05892 +E 0.27116 0.65769 0.06910 +S 0.55387 0.78184 0.13065 +I 0.72358 0.77535 0.33382 -- 1.7.10.2