X-Git-Url: http://source.jalview.org/gitweb/?p=jalview.git;a=blobdiff_plain;f=test%2Fjalview%2Fanalysis%2FAlignmentUtilsTests.java;fp=test%2Fjalview%2Fanalysis%2FAlignmentUtilsTests.java;h=06b51e6fd3e90f7064885338c18ee6ab6bf117c5;hp=4439bb9368dd94f3bc0a640ee0858c6872269185;hb=fbab824503f3746682d8bac0327e5ffe0e0fb8a5;hpb=2a27ba6c3c4a450f17eae24c592a565a62c1821f

diff --git a/test/jalview/analysis/AlignmentUtilsTests.java b/test/jalview/analysis/AlignmentUtilsTests.java
index 4439bb9..06b51e6 100644
--- a/test/jalview/analysis/AlignmentUtilsTests.java
+++ b/test/jalview/analysis/AlignmentUtilsTests.java
@@ -2533,4 +2533,71 @@ public class AlignmentUtilsTests
     assertEquals(s_as3, uas3.getSequenceAsString());
   }
 
+  /**
+   * Tests for the method that maps nucleotide to protein based on CDS features
+   */
+  @Test(groups = "Functional")
+  public void testMapCdsToProtein()
+  {
+    SequenceI peptide = new Sequence("pep", "KLQ");
+
+    /*
+     * Case 1: CDS 3 times length of peptide
+     * NB method only checks lengths match, not translation
+     */
+    SequenceI dna = new Sequence("dna", "AACGacgtCTCCT");
+    dna.createDatasetSequence();
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 1, 4, null));
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 9, 13, null));
+    MapList ml = AlignmentUtils.mapCdsToProtein(dna, peptide);
+    assertEquals(3, ml.getFromRatio());
+    assertEquals(1, ml.getToRatio());
+    assertEquals("[[1, 3]]",
+            Arrays.deepToString(ml.getToRanges().toArray()));
+    assertEquals("[[1, 4], [9, 13]]",
+            Arrays.deepToString(ml.getFromRanges().toArray()));
+
+    /*
+     * Case 2: CDS 3 times length of peptide + stop codon
+     * (note code does not currently check trailing codon is a stop codon)
+     */
+    dna = new Sequence("dna", "AACGacgtCTCCTTGA");
+    dna.createDatasetSequence();
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 1, 4, null));
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 9, 16, null));
+    ml = AlignmentUtils.mapCdsToProtein(dna, peptide);
+    assertEquals(3, ml.getFromRatio());
+    assertEquals(1, ml.getToRatio());
+    assertEquals("[[1, 3]]",
+            Arrays.deepToString(ml.getToRanges().toArray()));
+    assertEquals("[[1, 4], [9, 13]]",
+            Arrays.deepToString(ml.getFromRanges().toArray()));
+
+    /*
+     * Case 3: CDS not 3 times length of peptide - no mapping is made
+     */
+    dna = new Sequence("dna", "AACGacgtCTCCTTG");
+    dna.createDatasetSequence();
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 1, 4, null));
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 9, 15, null));
+    ml = AlignmentUtils.mapCdsToProtein(dna, peptide);
+    assertNull(ml);
+
+    /*
+     * Case 4: incomplete start codon corresponding to X in peptide
+     */
+    dna = new Sequence("dna", "ACGacgtCTCCTTGG");
+    dna.createDatasetSequence();
+    SequenceFeature sf = new SequenceFeature("CDS", "", 1, 3, null);
+    sf.setPhase("2"); // skip 2 positions (AC) to start of next codon (GCT)
+    dna.addSequenceFeature(sf);
+    dna.addSequenceFeature(new SequenceFeature("CDS", "", 8, 15, null));
+    peptide = new Sequence("pep", "XLQ");
+    ml = AlignmentUtils.mapCdsToProtein(dna, peptide);
+    assertEquals("[[2, 3]]",
+            Arrays.deepToString(ml.getToRanges().toArray()));
+    assertEquals("[[3, 3], [8, 12]]",
+            Arrays.deepToString(ml.getFromRanges().toArray()));
+  }
+
 }