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Main Page | Alphabetical List | Data Structures | File List | Data Fields | Globals
+

pairwise.h File Reference

#include <stdlib.h>
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+Include dependency graph for pairwise.h:

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Data Structures

struct  fasta

Functions

void fatal_error (char *message)
FILE * xfopen (const char *path, const char *mode)
void * xmalloc (size_t size)
void * xrealloc (void *ptr, size_t size)
int diff (char a, char b)
float pairwise (struct fasta *a, struct fasta *b)
void populate (struct fasta *a)
void check_length (struct fasta **array)
fasta ** read_fasta (FILE *fh)
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Function Documentation

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void check_length struct fasta **  array  ) 
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+ +

+Definition at line 160 of file pairwise.c. +

+References fatal_error(). +

+Referenced by main(). +

+

00160                                     {
+00161         int i, length;
+00162 
+00163         if (array[0] != NULL)
+00164                 length = strlen(array[0]->seq);
+00165         else {
+00166                 fprintf(stderr, "check_length() not passed an array of fasta structs\n");
+00167                 return;
+00168         }
+00169 
+00170         for (i = 0; array[i] != NULL; i++) {
+00171                 if (length != strlen(array[i]->seq)) {
+00172                         fatal_error("Not all of the sequences are the same length\n");
+00173                 }
+00174         }
+00175 }
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int diff char  a,
char  b
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+Definition at line 92 of file pairwise.c. +

+Referenced by pairwise(). +

+

00092                       {
+00093         if (a == b && a == '-')
+00094                 return 0;
+00095         if (a == b)
+00096                 return 1;
+00097         return 0;
+00098 }
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void fatal_error char *  message  ) 
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+Definition at line 53 of file pairwise.c. +

+Referenced by check_length(). +

+

00053                             {
+00054         printf(message);
+00055         exit(EXIT_FAILURE);
+00056 }
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float pairwise struct fasta a,
struct fasta b
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+ +

+Definition at line 106 of file pairwise.c. +

+References diff(), fasta::end, MAX, MIN, fasta::numres, fasta::seq, and fasta::start. +

+Referenced by main(). +

+

00106                                             {
+00107         float result;
+00108         int start, end, numres, i, id = 0;
+00109         
+00110         /* If the sequences don't overlap then the seq ID is 0 */
+00111         if (a->end < b->start || a->start > b->end)
+00112                 return 0;
+00113 
+00114         start = MIN( a->start, b->start );
+00115         end = MAX( a->end, b->end );
+00116         numres = MAX( a->numres, b->numres );
+00117 
+00118         for (i = start; i < end; i++)
+00119                 id += diff(a->seq[i], b->seq[i]);
+00120 
+00121         result = 100 * (float) id / (float) numres;
+00122 
+00123         return result;
+00124 }
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void populate struct fasta a  ) 
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+Definition at line 133 of file pairwise.c. +

+References fasta::end, fasta::numres, fasta::seq, and fasta::start. +

+Referenced by read_fasta(). +

+

00133                            {
+00134         int i;
+00135         int len = strlen(a->seq);
+00136 
+00137         a->numres = 0;
+00138         
+00139         for (i = 0; i <= len; i++) {
+00140                 if (a->seq[i] != '-') {
+00141                         a->start = i;
+00142                         break;
+00143                 }
+00144         }
+00145         for (i = len; i > 0; i--) {
+00146                 if (a->seq[i] != '-') {
+00147                         a->end = i;
+00148                         break;
+00149                 }
+00150         }
+00151         for (i = a->start; i < a->end; i++) {
+00152                 if (a->seq[i] != '-') {
+00153                         a->numres++;
+00154                 }
+00155         }
+00156 }
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struct fasta** read_fasta FILE *  fh  ) 
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+ +

+Definition at line 179 of file pairwise.c. +

+References ARRAY, FILEBUF, fasta::id, fasta::numres, populate(), read_fasta(), fasta::seq, xmalloc(), and xrealloc(). +

+Referenced by main(), and read_fasta(). +

+

00179                       {
+00180         int i, j, k, c, filesize = 1;
+00181         char *file;
+00182         struct fasta **array;
+00183 
+00184         array = (struct fasta **) xmalloc(ARRAY * sizeof(struct fasta *));
+00185         file = (char *) xmalloc(sizeof(char));
+00186 
+00187         /* Allocate initial space for the file */
+00188         file = xrealloc(file, sizeof(char) * filesize);
+00189         file[filesize] = '\0';
+00190 
+00191         /* Read in the file */
+00192         while ((c = getc(fh)) != EOF) {
+00193                 if (filesize % FILEBUF)
+00194                         file = xrealloc(file, sizeof(char) * (FILEBUF + filesize));
+00195 
+00196                 file[filesize] = c;
+00197                 filesize++;
+00198         }
+00199 
+00200         /* Parse the FASTA file into an array of structures */
+00201         for (i = 0, j = 0, k = 0; i < filesize; i++) {
+00202                 if (file[i] == '>') {
+00203                         if (j % ARRAY == 0)
+00204                                 array = (struct fasta **) xrealloc(array, sizeof(struct fasta *) * (j + ARRAY));
+00205 
+00206                         array[j] = (struct fasta *) xmalloc(sizeof(struct fasta));
+00207                         array[j]->id = (char *) xmalloc(sizeof(char));
+00208                         array[j]->seq = (char *) xmalloc(sizeof(char));
+00209                         array[j]->numres = 0;
+00210 
+00211                         i++;
+00212                         while (file[i] != '\0' && file[i] != '\n') {
+00213                                 if (k % ARRAY == 0)
+00214                                         array[j]->id = (char *) xrealloc(array[j]->id, sizeof(char) * (ARRAY + k));
+00215                                 array[j]->id[k] = file[i];
+00216                                 k++; i++;
+00217                         }
+00218                         array[j]->id = (char *) xrealloc(array[j]->id, sizeof(char) * (ARRAY + k));
+00219                         array[j]->id[k] = '\0';
+00220                         k = 0;
+00221 
+00222                         while (file[i] != '\0' && file[i] != '>') {
+00223                                 if (file[i] == '\n') {
+00224                                         i++;
+00225                                         continue;
+00226                                 }
+00227                                 if (k % ARRAY == 0)
+00228                                         array[j]->seq = (char *) xrealloc(array[j]->seq, sizeof(char) * (ARRAY + k));
+00229                                 array[j]->seq[k] = file[i];
+00230                                 k++; i++;
+00231                         }
+00232                         array[j]->seq = (char *) xrealloc(array[j]->seq, sizeof(char) * (ARRAY + k));
+00233                         array[j]->seq[k] = '\0';
+00234                         k = 0;
+00235                         i--;
+00236                         j++;
+00237                 }
+00238         }
+00239 
+00240         free(file);
+00241         array = (struct fasta **) xrealloc(array, sizeof(struct fasta *) * j);
+00242         array[j] = NULL;
+00243 
+00244         /* find the start and end points for the alignments */
+00245         for (i = 0; array[i] != NULL; i++) {
+00246                 populate(array[i]);
+00247         }
+00248 
+00249         return array;
+00250 }
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FILE* xfopen const char *  path,
const char *  mode
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+Definition at line 65 of file pairwise.c. +

+References fatal_sys_error(). +

+Referenced by main(). +

+

00065                                             {
+00066         FILE *fh;
+00067         fh = fopen(path, mode);
+00068         if (fh == NULL)
+00069                 fatal_sys_error("fopen returned NULL");
+00070         return fh;
+00071 }
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void* xmalloc size_t  size  ) 
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+Definition at line 74 of file pairwise.c. +

+References fatal_sys_error(). +

+Referenced by read_fasta(). +

+

00074                       {
+00075         void *ptr;
+00076         ptr = (void *) malloc(size);
+00077         if (ptr == NULL)
+00078                 fatal_sys_error("malloc returned NULL");
+00079         return ptr;
+00080 }
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void* xrealloc void *  ptr,
size_t  size
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+Definition at line 83 of file pairwise.c. +

+References fatal_sys_error(). +

+Referenced by read_fasta(). +

+

00083                                   {
+00084         ptr = (void *) realloc(ptr, size);
+00085         if (ptr == NULL && size != 0)
+00086                 fatal_sys_error("realloc returned NULL");
+00087         return ptr;
+00088 }
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Generated on Thu Jul 24 12:17:51 2003 for pairwise by + +doxygen +1.3.2
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