>>August 24, 1996 New programs - tfastx3, tfastx3_t, compare a protein sequence to forward and reverse translations of a DNA sequence database. An excellent replacement for tfasta3. Sun multiprocessing - change in thr_create() to use all CPU's if available. GCG formats - now can search with simple GCG-format query sequences and results with GCG format Swissprot and Genpept are more readable. >>August 26, 1996 Fixed bugs in tfastx3(_t) and fastx3(_t) including an ancient problem with aatran(). Less redundancy in gcg_ranlib(). >>August 31, 1996 Included support for BLOSUM62 (-s BL62) as per documentation. Rearranged Makefile's so that they would make everything in one pass. >>September 6, 1996 Corrected yet another problem with the fastx/tfastx code. Noticed that searching without optimized scores gave no optimized scores on the final list of scores - fixed this. The pvm version now does alignments - not thoroughly tested. >>September 13, 1996 Fixed display of best scores to stdout. Fixed problem with alignments when -o flag used. pvcompfa/pvcompsw have now been tested on DEC Alpha, Solaris X86, and SGI PVM implementations. Several bugs were corrected. >>September 18, 1996 Fixed bug selectbestz() that caused core dumps in pvcomplib.c (changes to pvcomplib.c, comp_thr.c, complib.c). >>September 23, 1996 Corrected showalign.c/pvm_showalign.c addressing bug found and fixed by Erik Wallin. (erikw@biokemi.su.se). >>October 15, 1996 Corrected bug so alternative scoring matrices are used. >>October 22, 1996 Remove singularities from regression routine. -z 0 now means no statistics (same as -z -1). No longer show alignment for 0 score. >>October 26, 1996 Fix problem with -b, -d when Z-values disabled. >>November 1, 1996 Altschul-Gish statistical estimates (-z 3) now work properly. Fix problem with mean_var==0.0.