P R O T E I N S E Q U E N C E D A T A B A S E of PIR-International Section 1. Fully Classified Entries Release 63.00, December 30, 1999 20032 sequences, 7820966 residues Protein Information Resource (PIR)* National Biomedical Research Foundation 3900 Reservoir Road, N.W., Washington, DC 20007, USA International Protein Information Munich Information Center for Database in Japan (JIPID) Protein Sequences (MIPS) Science University of Tokyo GSF-Forschungszentrum f. Umwelt und Gesundheit 2669 Yamazaki, Noda 278, Japan am Max-Planck-Instut f. Biochemie Am Klopferspitz 18, D-82152 Martinsried, FRG This database may be redistributed without prior consent, provided that this notice be given to each user and that the words "Derived from" shall precede this notice if the database has been altered by the redistributor. *PIR is a registered mark of NBRF. \\\ ENTRY CCHU #type complete TITLE cytochrome c - human ORGANISM #formal_name Homo sapiens #common_name man DATE 24-Apr-1984 #sequence_revision 30-Sep-1991 #text_change 28-Jun-1999 ACCESSIONS A31764; A05676; I55192; A00001 REFERENCE A31764 #authors Evans, M.J.; Scarpulla, R.C. #journal Proc. Natl. Acad. Sci. U.S.A. (1988) 85:9625-9629 #title The human somatic cytochrome c gene: two classes of processed pseudogenes demarcate a period of rapid molecular evolution. #cross-references MUID:89071748 #accession A31764 ##molecule_type DNA ##residues 1-105 ##label EVA ##cross-references GB:M22877; NID:g181241; PIDN:AAA35732.1; PID:g181242 REFERENCE A05676 #authors Matsubara, H.; Smith, E.L. #journal J. Biol. Chem. (1963) 238:2732-2753 #title Human heart cytochrome c. Chymotryptic peptides, tryptic peptides, and the complete amino acid sequence. #accession A05676 ##molecule_type protein ##residues 2-28;29-46;47-100;101-105 ##label MATS REFERENCE A00001 #authors Matsubara, H.; Smith, E.L. #journal J. Biol. Chem. (1962) 237:3575-3576 #title The amino acid sequence of human heart cytochrome c. #contents annotation #note 66-Leu is found in 10% of the molecules in pooled protein REFERENCE I55192 #authors Tanaka, Y.; Ashikari, T.; Shibano, Y.; Amachi, T.; Yoshizumi, H.; Matsubara, H. #journal J. Biochem. (1988) 103:954-961 #title Construction of a human cytochrome c gene and its functional expression in Saccharomyces cerevisiae. #cross-references MUID:89008207 #accession I55192 ##status translated from GB/EMBL/DDBJ ##molecule_type mRNA ##residues 78-105 ##label RES ##cross-references GB:D00265; NID:g2897691; PIDN:BAA00187.1; PID:d1000635; PID:g219557 GENETICS #introns 57/1 CLASSIFICATION #superfamily cytochrome c; cytochrome c homology KEYWORDS acetylated amino end; chromoprotein; electron transfer; heme; iron; mitochondrion; oxidative phosphorylation; polymorphism; respiratory chain FEATURE 2-105 #product cytochrome c #status experimental #label MAT\ 5-99 #domain cytochrome c homology #label CYC\ 2 #modified_site acetylated amino end (Gly) (in mature form) #status experimental\ 15,18 #binding_site heme (Cys) (covalent) #status experimental\ 19,81 #binding_site heme iron (His, Met) (axial ligands) #status predicted SUMMARY #length 105 #molecular-weight 11749 #checksum 3247 SEQUENCE 5 10 15 20 25 30 1 M G D V E K G K K I F I M K C S Q C H T V E K G G K H K T G 31 P N L H G L F G R K T G Q A P G Y S Y T A A N K N K G I I W 61 G E D T L M E Y L E N P K K Y I P G T K M I F V G I K K K E 91 E R A D L I A Y L K K A T N E /// ENTRY CCCZ #type complete TITLE cytochrome c - chimpanzee (tentative sequence) ORGANISM #formal_name Pan troglodytes #common_name chimpanzee DATE 17-Mar-1987 #sequence_revision 17-Mar-1987 #text_change 25-Apr-1997 ACCESSIONS A00002 REFERENCE A94601 #authors Needleman, S.B. #submission submitted to the Atlas, October 1968 #accession A00002 ##molecule_type protein ##residues 1-104 ##label NEE REFERENCE A94455 #authors Needleman, S.B.; Margoliash, E. #citation unpublished results, 1966, cited by Margoliash, E., and Fitch, W.M., Ann. N.Y. Acad. Sci. 151, 359-381, 1968 #contents annotation; compositions of chymotryptic peptides CLASSIFICATION #superfamily cytochrome c; cytochrome c homology KEYWORDS acetylated amino end; chromoprotein; electron transfer; heme; iron; mitochondrion; oxidative phosphorylation; respiratory chain FEATURE 4-98 #domain cytochrome c homology #label CYC\ 1 #modified_site acetylated amino end (Gly) #status predicted\ 14,17 #binding_site heme (Cys) (covalent) #status predicted\ 18,80 #binding_site heme iron (His, Met) (axial ligands) #status predicted SUMMARY #length 104 #molecular-weight 11617 #checksum 9501 SEQUENCE 5 10 15 20 25 30 1 G D V E K G K K I F I M K C S Q C H T V E K G G K H K T G P 31 N L H G L F G R K T G Q A P G Y S Y T A A N K N K G I I W G 61 E D T L M E Y L E N P K K Y I P G T K M I F V G I K K K E E 91 R A D L I A Y L K K A T N E /// ENTRY CCMQR #type complete TITLE cytochrome c - rhesus macaque (tentative sequence) ORGANISM #formal_name Macaca mulatta #common_name rhesus macaque DATE 17-Mar-1987 #sequence_revision 17-Mar-1987 #text_change 25-Apr-1997 ACCESSIONS A00003 REFERENCE A00003 #authors Rothfus, J.A.; Smith, E.L. #journal J. Biol. Chem. (1965) 240:4277-4283 #title Amino acid sequence of rhesus monkey heart cytochrome c. #cross-references MUID:66045191 #contents compositions of chymotryptic peptides; sequences of residues 55-61 and 68-70 #accession A00003 ##molecule_type protein ##residues 1-104 ##label ROT CLASSIFICATION #superfamily cytochrome c; cytochrome c homology KEYWORDS acetylated amino end; chromoprotein; electron transfer; heme; iron; mitochondrion; oxidative phosphorylation; respiratory chain FEATURE 4-98 #domain cytochrome c homology #label CYC\ 1 #modified_site acetylated amino end (Gly) #status experimental\ 14,17 #binding_site heme (Cys) (covalent) #status predicted\ 18,80 #binding_site heme iron (His, Met) (axial ligands) #status predicted SUMMARY #length 104 #molecular-weight 11605 #checksum 9512 SEQUENCE 5 10 15 20 25 30 1 G D V E K G K K I F I M K C S Q C H T V E K G G K H K T G P 31 N L H G L F G R K T G Q A P G Y S Y T A A N K N K G I T W G 61 E D T L M E Y L E N P K K Y I P G T K M I F V G I K K K E E 91 R A D L I A Y L K K A T N E /// ENTRY CCMKP #type complete TITLE cytochrome c - spider monkey ORGANISM #formal_name Ateles sp. #common_name spider monkey DATE 17-Dec-1982 #sequence_revision 17-Dec-1982 #text_change 25-Apr-1997 ACCESSIONS A00004 REFERENCE A00004 #authors Margoliash, E. #citation unpublished results, cited by Shelnutt, J.A., Rousseau, D.L., Dethmers, J.K., and Margoliash, E., Biochemistry 20, 6485-6497, 1981 #accession A00004 ##molecule_type protein ##residues 1-104 ##label MAR CLASSIFICATION #superfamily cytochrome c; cytochrome c homology KEYWORDS acetylated amino end; chromoprotein; electron transfer; heme; iron; mitochondrion; oxidative phosphorylation; respiratory chain FEATURE 4-98 #domain cytochrome c homology #label CYC\ 1 #modified_site acetylated amino end (Gly) #status predicted\ 14,17 #binding_site heme (Cys) (covalent) #status predicted\ 18,80 #binding_site heme iron (His, Met) (axial ligands) #status predicted SUMMARY #length 104 #molecular-weight 11710 #checksum 9066 SEQUENCE 5 10 15 20 25 30 1 G D V F K G K R I F I M K C S Q C H T V E K G G K H K T G P 31 N L H G L F G R K T G Q A S G F T Y T E A N K N K G I I W G 61 E D T L M E Y L E N P K K Y I P G T K M I F V G I K K K E E 91 R A D L I A Y L K K A T N E /// ENTRY CCMS #type complete TITLE cytochrome c - mouse ORGANISM #formal_name Mus musculus #common_name house mouse DATE 31-Dec-1990 #sequence_revision 30-Sep-1991 #text_change 11-Jun-1999 ACCESSIONS A23057; A04604; A00009 REFERENCE A23057 #authors Limbach, K.J.; Wu, R. #journal Nucleic Acids Res. (1985) 13:617-630 #title Characterization of a mouse somatic cytochrome c gene and three cytochrome c pseudogenes. #cross-references MUID:85215501 #accession A23057 ##molecule_type DNA ##residues 1-105 ##label LIM ##cross-references EMBL:X01756; NID:g50618; PIDN:CAA25899.1; PID:g50619 ##experimental_source strain BALB/c REFERENCE A04604 #authors Carlson, S.S.; Mross, G.A.; Wilson, A.C.; Mead, R.T.; Wolin, L.D.; Bowers, S.F.; Foley, N.T.; Muijsers, A.O.; Margoliash, E. #journal Biochemistry (1977) 16:1437-1442 #title Primary structure of mouse, rat, and guinea pig cytochrome c. #cross-references MUID:77134768 #accession A04604 ##molecule_type protein ##residues 2-105 ##label CAR ##experimental_source strain BALB/c GENETICS #introns 57/1 CLASSIFICATION #superfamily cytochrome c; cytochrome c homology KEYWORDS acetylated amino end; chromoprotein; electron transfer; heme; iron; mitochondrion; oxidative phosphorylation; respiratory chain FEATURE 2-105 #product cytochrome c #status experimental #label MAT\ 5-99 #domain cytochrome c homology #label CYC\ 2 #modified_site acetylated amino end (Gly) (in mature form) #status experimental\ 15,18 #binding_site heme (Cys) (covalent) #status experimental\ 19,81 #binding_site heme iron (His, Met) (axial ligands) #status predicted SUMMARY #length 105 #molecular-weight 11605 #checksum 1273 SEQUENCE 5 10 15 20 25 30 1 M G D V E K G K K I F V Q K C A Q C H T V E K G G K H K T G 31 P N L H G L F G R K T G Q A A G F S Y T D A N K N K G I T W 61 G E D T L M E Y L E N P K K Y I P G T K M I F A G I K K K G 91 E R A D L I A Y L K K A T N E ///