// $Id: // forester -- software libraries and applications // for genomics and evolutionary biology research. // // Copyright (C) 2010 Christian M Zmasek // Copyright (C) 2010 Sanford-Burnham Medical Research Institute // All rights reserved // // This library is free software; you can redistribute it and/or // modify it under the terms of the GNU Lesser General Public // License as published by the Free Software Foundation; either // version 2.1 of the License, or (at your option) any later version. // // This library is distributed in the hope that it will be useful, // but WITHOUT ANY WARRANTY; without even the implied warranty of // MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU // Lesser General Public License for more details. // // You should have received a copy of the GNU Lesser General Public // License along with this library; if not, write to the Free Software // Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA // // Contact: phylosoft @ gmail . com // WWW: https://sites.google.com/site/cmzmasek/home/software/forester package org.forester.msa; import java.io.IOException; import java.io.Writer; import java.util.ArrayList; import java.util.HashSet; import java.util.List; import java.util.Set; import org.forester.io.writers.SequenceWriter; import org.forester.io.writers.SequenceWriter.SEQ_FORMAT; import org.forester.sequence.BasicSequence; import org.forester.sequence.Sequence; import org.forester.sequence.Sequence.TYPE; import org.forester.util.ForesterUtil; public class BasicMsa implements Msa { private final char[][] _data; private final String[] _identifiers; private final TYPE _type; public BasicMsa( final int rows, final int columns, final TYPE type ) { if ( ( rows < 1 ) || ( columns < 1 ) ) { throw new IllegalArgumentException( "basic msa of size zero are illegal" ); } _data = new char[ rows ][ columns ]; _identifiers = new String[ rows ]; _type = type; } BasicMsa( final BasicMsa msa ) { _data = msa._data; _identifiers = msa._identifiers; _type = msa._type; } @Override public List asSequenceList() { final List seqs = new ArrayList(); for( int i = 0; i < getNumberOfSequences(); ++i ) { seqs.add( getSequence( i ) ); } return seqs; } private int determineMaxIdLength() { int max = 0; for( int row = 0; row < _data.length; ++row ) { final int l = _identifiers[ row ].toString().length(); if ( l > max ) { max = l; } } return max; } @Override public String getIdentifier( final int row ) { return _identifiers[ row ]; } @Override public int getLength() { return _data[ 0 ].length; } @Override public int getNumberOfSequences() { return _identifiers.length; } @Override public char getResidueAt( final int row, final int col ) { return _data[ row ][ col ]; } @Override public Sequence getSequence( final String id ) { for( int i = 0; i < getNumberOfSequences(); ++i ) { if ( getIdentifier( i ).equals( id ) ) { return getSequence( i ); } } return null; } @Override public Sequence getSequence( final int row ) { return new BasicSequence( getIdentifier( row ), _data[ row ], getType() ); } @Override public StringBuffer getSequenceAsString( final int row ) { final StringBuffer sb = new StringBuffer( _data[ 0 ].length ); for( int col = 0; col < _data[ 0 ].length; ++col ) { sb.append( getResidueAt( row, col ) ); } return sb; } @Override public TYPE getType() { return _type; } @Override public void setIdentifier( final int row, final String id ) { _identifiers[ row ] = id; } @Override public void setResidueAt( final int row, final int col, final char residue ) { _data[ row ][ col ] = residue; } @Override public String toString() { final int max = determineMaxIdLength() + 1; final StringBuffer sb = new StringBuffer(); for( int row = 0; row < _data.length; ++row ) { sb.append( ForesterUtil.pad( _identifiers[ row ].toString(), max, ' ', false ) ); for( int col = 0; col < _data[ 0 ].length; ++col ) { sb.append( getResidueAt( row, col ) ); } sb.append( ForesterUtil.LINE_SEPARATOR ); } return sb.toString(); } @Override public void write( final Writer w, final MSA_FORMAT format ) throws IOException { switch ( format ) { case PHYLIP: writeToPhylip( w ); break; case FASTA: writeToFasta( w ); break; default: throw new RuntimeException( "unknown format " + format ); } } private void writeToFasta( final Writer w ) throws IOException { SequenceWriter.writeSeqs( asSequenceList(), w, SEQ_FORMAT.FASTA, 100 ); } private void writeToPhylip( final Writer w ) throws IOException { final int max = determineMaxIdLength() + 1; for( int row = 0; row < _data.length; ++row ) { w.write( ForesterUtil.pad( _identifiers[ row ].toString(), max, ' ', false ).toString() ); for( int col = 0; col < _data[ 0 ].length; ++col ) { w.write( getResidueAt( row, col ) ); } w.write( ForesterUtil.LINE_SEPARATOR ); } } public static Msa createInstance( final List seqs ) { if ( seqs.size() < 1 ) { throw new IllegalArgumentException( "cannot create basic msa from less than one sequence" ); } final Set ids = new HashSet(); final int length = seqs.get( 0 ).getLength(); final BasicMsa msa = new BasicMsa( seqs.size(), length, seqs.get( 0 ).getType() ); for( int row = 0; row < seqs.size(); ++row ) { final Sequence seq = seqs.get( row ); if ( seq.getLength() != length ) { throw new IllegalArgumentException( "illegal attempt to build msa from sequences of unequal length" ); } if ( seq.getType() != msa.getType() ) { throw new IllegalArgumentException( "illegal attempt to build msa from sequences of different type" ); } if ( ids.contains( seq.getIdentifier() ) ) { throw new IllegalArgumentException( "illegal attempt to create msa with non-unique identifiers [" + seq.getIdentifier() + "]" ); } ids.add( seq.getIdentifier() ); msa.setIdentifier( row, seq.getIdentifier() ); for( int col = 0; col < length; ++col ) { msa._data[ row ][ col ] = seq.getResidueAt( col ); } } return msa; } @Override public List getColumnAt( final int col ) { final List column = new ArrayList(); for( int row = 0; row < getNumberOfSequences(); ++row ) { column.add( getResidueAt( row, col ) ); } return column; } }