#------------------------------------------------------------------------------- # Jalview - A Sequence Alignment Editor and Viewer (Version 2.5.1) # Copyright (C) 2010 J Procter, AM Waterhouse, G Barton, M Clamp, S Searle # # This file is part of Jalview. # # Jalview is free software: you can redistribute it and/or # modify it under the terms of the GNU General Public License # as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. # # Jalview is distributed in the hope that it will be useful, but # WITHOUT ANY WARRANTY; without even the implied warranty # of MERCHANTABILITY or FITNESS FOR A PARTICULAR # PURPOSE. See the GNU General Public License for more details. # # You should have received a copy of the GNU General Public License along with Jalview. If not, see . #------------------------------------------------------------------------------- Pairwise Alignment

Pairwise alignment (Proteins only)

This calculation is performed on the selected sequences only. Java is not the fastest language in the world and aligning more than a handful of sequences will take a fair amount of time.
For each pair of sequences the best global alignment is found using BLOSUM62 as the scoring matrix. The scores reported are the raw scores. The sequences are aligned using a dynamic programming technique and using the following gap penalties :

Gap open : 12
Gap extend : 2

When you select the pairwise alignment option a new window will come up which will display the alignments in a text format as they are calculated. Also displayed is information about the alignment such as alignment score, length and percentage identity between the sequences.