/* * Jalview - A Sequence Alignment Editor and Viewer * Copyright (C) 2006 AM Waterhouse, J Procter, G Barton, M Clamp, S Searle * * This program is free software; you can redistribute it and/or * modify it under the terms of the GNU General Public License * as published by the Free Software Foundation; either version 2 * of the License, or (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program; if not, write to the Free Software * Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA */ package jalview.datamodel; import jalview.analysis.*; import jalview.util.*; import java.util.*; /** Data structure to hold and manipulate a multiple sequence alignment */ public class Alignment implements AlignmentI { protected Alignment dataset; protected Vector sequences; protected Vector groups = new Vector(); protected char gapCharacter = '-'; protected int type = NUCLEOTIDE; public static final int PROTEIN = 0; public static final int NUCLEOTIDE = 1; /** DOCUMENT ME!! */ public AlignmentAnnotation[] annotations; HiddenSequences hiddenSequences = new HiddenSequences(this); private void initAlignment(SequenceI[] seqs) { int i=0; if( jalview.util.Comparison.isNucleotide(seqs)) type = NUCLEOTIDE; else type = PROTEIN; sequences = new Vector(); for (i = 0; i < seqs.length; i++) { sequences.addElement(seqs[i]); } } /** Make an alignment from an array of Sequences. * * @param sequences */ public Alignment(SequenceI[] seqs) { initAlignment(seqs); } /** * Make a new alignment from an array of SeqCigars * @param seqs SeqCigar[] */ public Alignment(SeqCigar[] alseqs) { SequenceI[] seqs = SeqCigar.createAlignmentSequences(alseqs, gapCharacter, new ColumnSelection(), null); initAlignment(seqs); } /** * Make a new alignment from an CigarArray * JBPNote - can only do this when compactAlignment does not contain hidden regions. * JBPNote - must also check that compactAlignment resolves to a set of SeqCigars - or construct them appropriately. * @param compactAlignment CigarArray */ public static AlignmentI createAlignment(CigarArray compactAlignment) { throw new Error("Alignment(CigarArray) not yet implemented"); // this(compactAlignment.refCigars); } /** * DOCUMENT ME! * * @return DOCUMENT ME! */ public Vector getSequences() { return sequences; } public SequenceI [] getSequencesArray() { SequenceI [] reply = new SequenceI[sequences.size()]; for(int i=0; i width) { width = seqs[i].getLength(); } } int startCol = -1, endCol = -1; boolean delete = true; for (int i = 0; i < width; i++) { delete = true; for (j = 0; j < jSize; j++) { if (seqs[j].getLength() > i) { if (!jalview.util.Comparison.isGap(seqs[j].getCharAt(i))) { if(delete) endCol = i; delete = false; break; } } } if(delete && startCol==-1) { startCol = i; } if (!delete && startCol > -1) { deleteColumns(seqs, startCol, endCol); if (shiftrecord!=null) { shiftrecord.addShift(startCol, 1+endCol-startCol); } width -= (endCol - startCol); i -= (endCol - startCol); startCol = -1; endCol = -1; } } if (delete && startCol > -1) { deleteColumns(seqs, startCol, endCol); if (shiftrecord!=null) { shiftrecord.addShift(startCol, 1+endCol-startCol); } } } /** Removes a range of columns (start to end inclusive). * * @param seqs Sequences to remove columns from * @param start Start column in the alignment * @param end End column in the alignment */ public void deleteColumns(SequenceI [] seqs, int start, int end) { for(int i=0; iseqs[j].getLength()) { sequences.removeElement(seqs[j]); j--; jSize--; } else { seqs[j].setStart(newstart); seqs[j].setSequence(seqs[j].getSequence().substring(i)); } } } /** * DOCUMENT ME! * * @param i DOCUMENT ME! */ public void trimRight(int i) { SequenceI[] seqs = getVisibleAndRepresentedSeqs(); int j, jSize = seqs.length; for (j = 0; j < jSize; j++) { int newend = seqs[j].findPosition(i); seqs[j].setEnd(newend); if(seqs[j].getLength()>i) seqs[j].setSequence(seqs[j].getSequence().substring(0, i + 1)); } } /** * DOCUMENT ME! * * @param s DOCUMENT ME! */ public void deleteSequence(SequenceI s) { for (int i = 0; i < getHeight(); i++) { if (getSequenceAt(i) == s) { deleteSequence(i); } } } /** * DOCUMENT ME! * * @param i DOCUMENT ME! */ public void deleteSequence(int i) { sequences.removeElementAt(i); } /** */ public SequenceGroup findGroup(SequenceI s) { for (int i = 0; i < this.groups.size(); i++) { SequenceGroup sg = (SequenceGroup) groups.elementAt(i); if (sg.getSequences(false).contains(s)) { return sg; } } return null; } /** * DOCUMENT ME! * * @param s DOCUMENT ME! * * @return DOCUMENT ME! */ public SequenceGroup[] findAllGroups(SequenceI s) { Vector temp = new Vector(); int gSize = groups.size(); for (int i = 0; i < gSize; i++) { SequenceGroup sg = (SequenceGroup) groups.elementAt(i); if(sg==null || sg.getSequences(false)==null) { this.deleteGroup(sg); gSize--; continue; } if (sg.getSequences(false).contains(s)) { temp.addElement(sg); } } SequenceGroup[] ret = new SequenceGroup[temp.size()]; for (int i = 0; i < temp.size(); i++) { ret[i] = (SequenceGroup) temp.elementAt(i); } return ret; } /** */ public void addGroup(SequenceGroup sg) { if (!groups.contains(sg)) { groups.addElement(sg); } } /** * DOCUMENT ME! */ public void deleteAllGroups() { groups.removeAllElements(); int i = 0; while (i < sequences.size()) { SequenceI s = getSequenceAt(i); s.setColor(java.awt.Color.white); i++; } } /** */ public void deleteGroup(SequenceGroup g) { if (groups.contains(g)) { groups.removeElement(g); } } /** */ public SequenceI findName(String name) { int i = 0; while (i < sequences.size()) { if (getSequenceAt(i).getName().equals(name)) { return getSequenceAt(i); } i++; } return null; } public SequenceI [] findSequenceMatch(String name) { Vector matches = new Vector(); int i = 0; while (i < sequences.size()) { if (getSequenceAt(i).getName().equals(name)) { matches.addElement(getSequenceAt(i)); } i++; } SequenceI [] result = new SequenceI[matches.size()]; for(i=0; i maxLength) { maxLength = getSequenceAt(i).getLength(); } } return maxLength; } /** * DOCUMENT ME! * * @return DOCUMENT ME! */ public int getMaxIdLength() { int max = 0; int i = 0; while (i < sequences.size()) { SequenceI seq = getSequenceAt(i); String tmp = seq.getName() + "/" + seq.getStart() + "-" + seq.getEnd(); if (tmp.length() > max) { max = tmp.length(); } i++; } return max; } /** * DOCUMENT ME! * * @param gc DOCUMENT ME! */ public void setGapCharacter(char gc) { gapCharacter = gc; for (int i = 0; i < sequences.size(); i++) { Sequence seq = (Sequence) sequences.elementAt(i); seq.setSequence( seq.getSequence().replace('.', gc) ); seq.setSequence( seq.getSequence().replace('-', gc) ); seq.setSequence( seq.getSequence().replace(' ', gc) ); } } /** * DOCUMENT ME! * * @return DOCUMENT ME! */ public char getGapCharacter() { return gapCharacter; } /** * DOCUMENT ME! * * @return DOCUMENT ME! */ public Vector getAAFrequency() { return AAFrequency.calculate(sequences, 0, getWidth()); } /** * DOCUMENT ME! * * @return DOCUMENT ME! */ public boolean isAligned() { int width = getWidth(); for (int i = 0; i < sequences.size(); i++) { if (getSequenceAt(i).getLength() != width) { return false; } } return true; } /** * DOCUMENT ME! * * @param aa DOCUMENT ME! */ public void deleteAnnotation(AlignmentAnnotation aa) { int aSize = 1; if (annotations != null) { aSize = annotations.length; } AlignmentAnnotation[] temp = new AlignmentAnnotation[aSize - 1]; int tIndex = 0; for (int i = 0; i < aSize; i++) { if (annotations[i] == aa) { continue; } temp[tIndex] = annotations[i]; tIndex++; } annotations = temp; } public void adjustSequenceAnnotations() { if(annotations!=null) { for (int a = 0; a < annotations.length; a++) { if (annotations[a].sequenceRef != null) { annotations[a].adjustForAlignment(); } } } } /** * DOCUMENT ME! * * @param aa DOCUMENT ME! */ public void addAnnotation(AlignmentAnnotation aa) { int aSize = 1; if (annotations != null) { aSize = annotations.length + 1; } AlignmentAnnotation[] temp = new AlignmentAnnotation[aSize]; temp[aSize-1] = aa; int i = 0; if (aSize > 1) { for (i = 0; i < (aSize-1); i++) { temp[i] = annotations[i]; } } annotations = temp; } public void setAnnotationIndex(AlignmentAnnotation aa, int index) { if(aa==null || annotations==null || annotations.length-1 maxLength; j--) { if (j > maxLength && !jalview.util.Comparison.isGap( current.getCharAt(j))) { maxLength = j; break; } } } maxLength++; for (int i = 0; i < sequences.size(); i++) { current = getSequenceAt(i); if (current.getLength() < maxLength) { current.insertCharAt(maxLength - 1, gapCharacter); modified=true; } else if(current.getLength() > maxLength) { current.deleteChars(maxLength, current.getLength()); } } return modified; } public HiddenSequences getHiddenSequences() { return hiddenSequences; } SequenceI [] getVisibleAndRepresentedSeqs() { if(hiddenSequences==null || hiddenSequences.getSize()<1) return getSequencesArray(); Vector seqs = new Vector(); SequenceI seq; SequenceGroup hidden; for (int i = 0; i < sequences.size(); i++) { seq = (SequenceI) sequences.elementAt(i); seqs.addElement(seq); hidden = seq.getHiddenSequences(); if(hidden!=null) { for(int j=0; j