/*
* Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
* Copyright (C) $$Year-Rel$$ The Jalview Authors
*
* This file is part of Jalview.
*
* Jalview is free software: you can redistribute it and/or
* modify it under the terms of the GNU General Public License
* as published by the Free Software Foundation, either version 3
* of the License, or (at your option) any later version.
*
* Jalview is distributed in the hope that it will be useful, but
* WITHOUT ANY WARRANTY; without even the implied warranty
* of MERCHANTABILITY or FITNESS FOR A PARTICULAR
* PURPOSE. See the GNU General Public License for more details.
*
* You should have received a copy of the GNU General Public License
* along with Jalview. If not, see .
* The Jalview Authors are detailed in the 'AUTHORS' file.
*/
package jalview.ext.ensembl;
import jalview.datamodel.SequenceFeature;
import jalview.datamodel.SequenceI;
import jalview.io.gff.SequenceOntologyFactory;
import jalview.io.gff.SequenceOntologyI;
import java.util.ArrayList;
import java.util.List;
/**
* A client for direct fetching of CDS sequences from Ensembl (i.e. that part of
* the genomic sequence that is translated to protein)
*
* TODO: not currently used as CDS sequences are computed from CDS features on
* transcripts - delete this class?
*
* @author gmcarstairs
*
*/
public class EnsemblCds extends EnsemblSeqProxy
{
/*
* fetch cds features on genomic sequence (to identify the CDS regions)
* and exon and variation features (to retain for display)
*/
private static final EnsemblFeatureType[] FEATURES_TO_FETCH = {
EnsemblFeatureType.cds, EnsemblFeatureType.exon,
EnsemblFeatureType.variation };
/**
* Default constructor (to use rest.ensembl.org)
*/
public EnsemblCds()
{
super();
}
/**
* Constructor given the target domain to fetch data from
*
* @param d
*/
public EnsemblCds(String d)
{
super(d);
}
@Override
public String getDbName()
{
return "ENSEMBL (CDS)";
}
@Override
protected EnsemblSeqType getSourceEnsemblType()
{
return EnsemblSeqType.CDS;
}
@Override
protected EnsemblFeatureType[] getFeaturesToFetch()
{
return FEATURES_TO_FETCH;
}
/**
* Answers true unless the feature type is 'CDS' (or a sub-type of CDS in the
* Sequence Ontology). CDS features are only retrieved in order to identify
* the cds sequence range, and are redundant information on the cds sequence
* itself.
*/
@Override
protected boolean retainFeature(SequenceFeature sf, String accessionId)
{
if (SequenceOntologyFactory.getInstance().isA(sf.getType(),
SequenceOntologyI.CDS))
{
return false;
}
return featureMayBelong(sf, accessionId);
}
/**
* Answers a list of sequence features (if any) whose type is 'CDS' (or a
* subtype of CDS in the Sequence Ontology), and whose Parent is the
* transcript we are retrieving
*/
@Override
protected List getIdentifyingFeatures(SequenceI seq,
String accId)
{
List result = new ArrayList<>();
List sfs = seq.getFeatures()
.getFeaturesByOntology(SequenceOntologyI.CDS);
for (SequenceFeature sf : sfs)
{
String parentFeature = (String) sf.getValue(PARENT);
if (accId.equals(parentFeature))
{
result.add(sf);
}
}
return result;
}
/**
* Overrides this method to trivially return a range which is the whole of the
* nucleotide sequence. This is both faster than scanning for CDS features,
* and also means we don't need to keep CDS features on CDS sequence (where
* they are redundant information).
*/
protected List getCdsRanges(SequenceI dnaSeq)
{
int len = dnaSeq.getLength();
List ranges = new ArrayList<>();
ranges.add(new int[] { 1, len });
return ranges;
}
}