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<!--
- * Jalview - A Sequence Alignment Editor and Viewer (Version 2.8.2)
- * Copyright (C) 2014 The Jalview Authors
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
*
* This file is part of Jalview.
*
<title>What's new ?</title>
</head>
<body>
- <p>
- <strong>What's new ?</strong>
- </p>
- <p>
- Jalview 2.8.2 is the first release produced by our new core
- development team.<br /> It incorporates many minor improvements and
- bug-fixes, and new features for working with 3D structure data,
- shading alignments by secondary structure and generation of alignment
- figures as Scalable Vector Graphics. <br />The majority of
- improvements in this version of Jalview concern the desktop
- application. As ever, the highlights are detailed below,
- and the full list is given in the <a
- href="releases.html#Jalview.2.8.2">Jalview 2.8.2 Release Notes</a>.
- </p>
- <p>
- <strong>Annotation visualisation</strong> <br /> The alignment window
- includes a new <em>Annotations</em> menu which provides controls for
- the layout and display of sequence, group and alignment associated
- annotation rows. It also now includes the <em>Autocalculated
- Annotation</em> submenu (formerly located in the View menu), which
- includes settings for the calculation and display of sequence
- consensus, logos, and amino acid conservation for the alignment and
- subgroups.
- </p>
- <p>
- <strong>Sequence associated annotation</strong><br /> New controls
- have also been added to the Sequence ID popup menu for the propagation
- and display of sequence associated annotation such as secondary
- structure assignments and disorder predictions. Annotation associated
- with one or a group of sequence already shown on the alignment may be
- shown or hidden, and any available annotation from 3D structure or
- calculations performed in other Jalview windows can be copied to the
- alignment
- <em>via</em> the <strong>Add Reference Annotation</strong> option.<br />
- The <strong>Colour by annotation</strong> function has also been
- improved, allowing secondary structure annotation to be used to shade
- sequences and alignment columns. Protein sequences can be coloured
- according to the presence of a helix or sheet at each position, and
- RNA sequences can be shaded according to each structure's stem/helix
- pattern - which enables different RNA folding topologies to be quickly
- identified.
- </p>
- <p>
- <strong>3D Structural data analysis and display</strong><br />
- Jalview now employs Jmol's PDB data API to retrieve secondary
- structure assignments made by the DSSP algorithm. It can also employ
- web services to obtain secondary structure assignments from RNA
- structures. These assignments are shown as sequence associated
- annotation for sequences which have cross-references to the PDB, or
- have had PDB files associated with them via the <em>Structures</em>
- submenu of the sequence ID popup menu. The extraction and display of
- secondary structure and B-factor column annotation is controlled <em>via</em>
- a new <strong>Structure</strong> tab in the Jalview Desktop's
- Preferences dialog box.
- </p>
- <p>
- <Strong>Interoperation with UCSF Chimera</Strong><br /> The desktop
- application can now be configured to employ UCSF Chimera for the
- display of 3D structure data. UCSF Chimera is a python-based
- high-performance molecular graphics and animation system developed by
- the Resource for Biocomputing, Visualisation, and Informatics at the
- University of California.<br />Jalview employs the 'StructureViz'
- communication mechanism developed for Cytoscape by Morris et al.
- (http://www.ncbi.nlm.nih.gov/pubmed/17623706) in 2007. This mechanism
- allows Jalview to send commands to Chimera, enabling structures to be
- superimposed and shaded according to associated multiple aligmment
- views. <br />Support for Chimera in Jalview 2.8.2 is experimental, and we
- would appreciate feedback ! Please send your comments to
- jalview-discuss@jalview.org, and keep up to date with this feature's
- development via http://issues.jalview.org/browse/JAL-1333.
- </p>
- <p>
- <strong>Export of alignment figures as Scalable Vector
- Graphics</strong> <br />Scalable Vector Graphics (SVG) files are now widely
- supported by web browsers and graphics design programs, and allow
- high-quality graphics for interactive exploration and publication.
- Jalview now supports the generation of SVGs interactively (via the
- Export) menu, and from the command line for server-side figure
- generation.
- </p>
-
+ <p>
+ <strong>What's new in Jalview 2.10.5 ?</strong>
+ </p>
+ <p>Jalview 2.10.5 is a minor release that includes critical
+ patches for users working with Ensembl, RNA secondary structure
+ annotation, and those running Jalview on OSX with Java 10.</p>
+ <ul>
+ <li>Jalview's default memory limit increased to 1G. <br/>If you have
+ problems starting Jalview 2.10.5 and you have 1G or less
+ physical memory on your machine, you will need to <a
+ href="memory.html#memsetting">reduce the memory</a> allocated to
+ Jalview.
+ </li>
+ <li>EPS, PNG and SVG export now includes hidden sequence
+ markers, and representative sequences are marked in bold.</li>
+ <li>Ensembl Client updated for Ensembl Rest API v7.<br />The
+ latest Ensembl API is not backwards compatible with earlier
+ versions of Jalview, so if you require Ensembl functionality you
+ will need to install this release.
+ </li>
+ <li>Improved support for VIENNA extended dot-bracket notation
+ for RNA secondary structure.</li>
+ <li>Positional and selected region highlighting in VARNA
+ 'trimmed sequence' view made more reliable.</li>
+ </ul>
+ <p>
+ The full list of bugs fixed in this release can be found in the <a
+ href="releases.html#Jalview.2.10.5">2.10.5 Release Notes</a>. The
+ majority of bug fixes and improvements in 2.10.5 are due to Jalview users
+ contacting us via the jalview-discuss email list. Thanks to everyone
+ who took the time to help make Jalview better !
+ </p>
+ <p>
+ <strong>Jalview and Java 10</strong>
+ </p>
+ <p>This release addresses a critical bug for OSX users who are
+ running Jalview with Java 10 which can prevent files being saved
+ correctly through the 'Save As' dialog box.</p>
+ <em>Known Issues</em>
+ <ul>
+ <li>OSX: The 'Open File' dialog for Jalview's Groovy Console
+ appears with the title 'Save As', and attempting to select a file to load yields a FileNotFound exception.</br>The workaround is to first clear the 'Untitled' filename before selecting the file you wish to load.
+ </li>
+ <li>OSX: Links don't open when clicked on or via the Sequence or Alignment window popup menu.</li>
+ <li>OSX (Webstart): Jalview only displays old news feed items</li>
+ </ul>
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