-/*\r
- * Jalview - A Sequence Alignment Editor and Viewer (Version 2.4)\r
- * Copyright (C) 2008 AM Waterhouse, J Procter, G Barton, M Clamp, S Searle\r
- * \r
- * This program is free software; you can redistribute it and/or\r
- * modify it under the terms of the GNU General Public License\r
- * as published by the Free Software Foundation; either version 2\r
- * of the License, or (at your option) any later version.\r
- * \r
- * This program is distributed in the hope that it will be useful,\r
- * but WITHOUT ANY WARRANTY; without even the implied warranty of\r
- * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the\r
- * GNU General Public License for more details.\r
- * \r
- * You should have received a copy of the GNU General Public License\r
- * along with this program; if not, write to the Free Software\r
- * Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA\r
- */\r
-package jalview.datamodel;\r
-\r
-import java.util.Enumeration;\r
-import java.util.Vector;\r
-\r
-import jalview.util.MapList;\r
-\r
-/**\r
- * Stores mapping between the columns of a protein alignment and a DNA alignment\r
- * and a list of individual codon to amino acid mappings between sequences.\r
- */\r
-\r
-public class AlignedCodonFrame\r
-{\r
- /**\r
- * array of nucleotide positions for aligned codons at column of aligned\r
- * proteins.\r
- */\r
- public int[][] codons = null;\r
-\r
- /**\r
- * width of protein sequence alignement implicit assertion that codons.length >=\r
- * aaWidth\r
- */\r
- public int aaWidth = 0;\r
-\r
- /**\r
- * initialise codon frame with a nominal alignment width\r
- * \r
- * @param aWidth\r
- */\r
- public AlignedCodonFrame(int aWidth)\r
- {\r
- if (aWidth <= 0)\r
- {\r
- codons = null;\r
- return;\r
- }\r
- codons = new int[aWidth][];\r
- for (int res = 0; res < aWidth; res++)\r
- codons[res] = null;\r
- }\r
-\r
- /**\r
- * ensure that codons array is at least as wide as aslen residues\r
- * \r
- * @param aslen\r
- * @return (possibly newly expanded) codon array\r
- */\r
- public int[][] checkCodonFrameWidth(int aslen)\r
- {\r
- if (codons.length <= aslen + 1)\r
- {\r
- // probably never have to do this ?\r
- int[][] c = new int[codons.length + 10][];\r
- for (int i = 0; i < codons.length; i++)\r
- {\r
- c[i] = codons[i];\r
- codons[i] = null;\r
- }\r
- codons = c;\r
- }\r
- return codons;\r
- }\r
-\r
- /**\r
- * @return width of aligned translated amino acid residues\r
- */\r
- public int getaaWidth()\r
- {\r
- return aaWidth;\r
- }\r
-\r
- /**\r
- * TODO: not an ideal solution - we reference the aligned amino acid sequences\r
- * in order to make insertions on them Better would be dnaAlignment and\r
- * aaAlignment reference....\r
- */\r
- Vector a_aaSeqs = new Vector();\r
-\r
- /**\r
- * increase aaWidth by one and insert a new aligned codon position space at\r
- * aspos.\r
- * \r
- * @param aspos\r
- */\r
- public void insertAAGap(int aspos, char gapCharacter)\r
- {\r
- // this aa appears before the aligned codons at aspos - so shift them in\r
- // each pair of mapped sequences\r
- aaWidth++;\r
- if (a_aaSeqs != null)\r
- {\r
- // we actually have to modify the aligned sequences here, so use the\r
- // a_aaSeqs vector\r
- Enumeration sq = a_aaSeqs.elements();\r
- while (sq.hasMoreElements())\r
- {\r
- ((SequenceI) sq.nextElement()).insertCharAt(aspos, gapCharacter);\r
- }\r
- }\r
- checkCodonFrameWidth(aspos);\r
- if (aspos < aaWidth)\r
- {\r
- aaWidth++;\r
- System.arraycopy(codons, aspos, codons, aspos + 1, aaWidth - aspos);\r
- codons[aspos] = null; // clear so new codon position can be marked.\r
- }\r
- }\r
-\r
- public void setAaWidth(int aapos)\r
- {\r
- aaWidth = aapos;\r
- }\r
-\r
- /**\r
- * tied array of na Sequence objects.\r
- */\r
- SequenceI[] dnaSeqs = null;\r
-\r
- /**\r
- * tied array of Mappings to protein sequence Objects and SequenceI[]\r
- * aaSeqs=null; MapLists where eac maps from the corresponding dnaSeqs element\r
- * to corresponding aaSeqs element\r
- */\r
- Mapping[] dnaToProt = null;\r
-\r
- /**\r
- * add a mapping between the dataset sequences for the associated dna and\r
- * protein sequence objects\r
- * \r
- * @param dnaseq\r
- * @param aaseq\r
- * @param map\r
- */\r
- public void addMap(SequenceI dnaseq, SequenceI aaseq, MapList map)\r
- {\r
- int nlen = 1;\r
- if (dnaSeqs != null)\r
- {\r
- nlen = dnaSeqs.length + 1;\r
- }\r
- SequenceI[] ndna = new SequenceI[nlen];\r
- Mapping[] ndtp = new Mapping[nlen];\r
- if (dnaSeqs != null)\r
- {\r
- System.arraycopy(dnaSeqs, 0, ndna, 0, dnaSeqs.length);\r
- System.arraycopy(dnaToProt, 0, ndtp, 0, dnaSeqs.length);\r
- }\r
- dnaSeqs = ndna;\r
- dnaToProt = ndtp;\r
- nlen--;\r
- dnaSeqs[nlen] = (dnaseq.getDatasetSequence() == null) ? dnaseq : dnaseq\r
- .getDatasetSequence();\r
- Mapping mp = new Mapping(map);\r
- // JBPNote DEBUG! THIS !\r
- // dnaseq.transferAnnotation(aaseq, mp);\r
- // aaseq.transferAnnotation(dnaseq, new Mapping(map.getInverse()));\r
- mp.to = (aaseq.getDatasetSequence() == null) ? aaseq : aaseq\r
- .getDatasetSequence();\r
- a_aaSeqs.addElement(aaseq);\r
- dnaToProt[nlen] = mp;\r
- }\r
-\r
- public SequenceI[] getdnaSeqs()\r
- {\r
- return dnaSeqs;\r
- }\r
-\r
- public SequenceI[] getAaSeqs()\r
- {\r
- if (dnaToProt == null)\r
- return null;\r
- SequenceI[] sqs = new SequenceI[dnaToProt.length];\r
- for (int sz = 0; sz < dnaToProt.length; sz++)\r
- {\r
- sqs[sz] = dnaToProt[sz].to;\r
- }\r
- return sqs;\r
- }\r
-\r
- public MapList[] getdnaToProt()\r
- {\r
- if (dnaToProt == null)\r
- return null;\r
- MapList[] sqs = new MapList[dnaToProt.length];\r
- for (int sz = 0; sz < dnaToProt.length; sz++)\r
- {\r
- sqs[sz] = dnaToProt[sz].map;\r
- }\r
- return sqs;\r
- }\r
-\r
- public Mapping[] getProtMappings()\r
- {\r
- return dnaToProt;\r
- }\r
-\r
- /**\r
- * \r
- * @param sequenceRef\r
- * @return null or corresponding aaSeq entry for dnaSeq entry\r
- */\r
- public SequenceI getAaForDnaSeq(SequenceI dnaSeqRef)\r
- {\r
- if (dnaSeqs == null)\r
- {\r
- return null;\r
- }\r
- SequenceI dnads = dnaSeqRef.getDatasetSequence();\r
- for (int ds = 0; ds < dnaSeqs.length; ds++)\r
- {\r
- if (dnaSeqs[ds] == dnaSeqRef || dnaSeqs[ds] == dnads)\r
- return dnaToProt[ds].to;\r
- }\r
- return null;\r
- }\r
-\r
- /**\r
- * \r
- * @param sequenceRef\r
- * @return null or corresponding aaSeq entry for dnaSeq entry\r
- */\r
- public SequenceI getDnaForAaSeq(SequenceI aaSeqRef)\r
- {\r
- if (dnaToProt == null)\r
- {\r
- return null;\r
- }\r
- SequenceI aads = aaSeqRef.getDatasetSequence();\r
- for (int as = 0; as < dnaToProt.length; as++)\r
- {\r
- if (dnaToProt[as].to == aaSeqRef || dnaToProt[as].to == aads)\r
- return dnaSeqs[as];\r
- }\r
- return null;\r
- }\r
-\r
- /**\r
- * test to see if codon frame involves seq in any way\r
- * \r
- * @param seq\r
- * a nucleotide or protein sequence\r
- * @return true if a mapping exists to or from this sequence to any translated\r
- * sequence\r
- */\r
- public boolean involvesSequence(SequenceI seq)\r
- {\r
- return getAaForDnaSeq(seq) != null || getDnaForAaSeq(seq) != null;\r
- }\r
-\r
- /**\r
- * Add search results for regions in other sequences that translate or are\r
- * translated from a particular position in seq\r
- * \r
- * @param seq\r
- * @param index\r
- * position in seq\r
- * @param results\r
- * where highlighted regions go\r
- */\r
- public void markMappedRegion(SequenceI seq, int index,\r
- SearchResults results)\r
- {\r
- if (dnaToProt == null)\r
- {\r
- return;\r
- }\r
- int[] codon;\r
- SequenceI ds = seq.getDatasetSequence();\r
- for (int mi = 0; mi < dnaToProt.length; mi++)\r
- {\r
- if (dnaSeqs[mi] == seq || dnaSeqs[mi] == ds)\r
- {\r
- // DEBUG System.err.println("dna pos "+index);\r
- codon = dnaToProt[mi].map.locateInTo(index, index);\r
- if (codon != null)\r
- {\r
- for (int i = 0; i < codon.length; i += 2)\r
- {\r
- results.addResult(dnaToProt[mi].to, codon[i], codon[i + 1]);\r
- }\r
- }\r
- }\r
- else if (dnaToProt[mi].to == seq || dnaToProt[mi].to == ds)\r
- {\r
- // DEBUG System.err.println("aa pos "+index);\r
- {\r
- codon = dnaToProt[mi].map.locateInFrom(index, index);\r
- if (codon != null)\r
- {\r
- for (int i = 0; i < codon.length; i += 2)\r
- {\r
- results.addResult(dnaSeqs[mi], codon[i], codon[i + 1]);\r
- }\r
- }\r
- }\r
- }\r
- }\r
- }\r
-}\r
+/*
+ * Jalview - A Sequence Alignment Editor and Viewer (Version 2.8.1)
+ * Copyright (C) 2014 The Jalview Authors
+ *
+ * This file is part of Jalview.
+ *
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License
+ * as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version.
+ *
+ * Jalview is distributed in the hope that it will be useful, but
+ * WITHOUT ANY WARRANTY; without even the implied warranty
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+ * PURPOSE. See the GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License along with Jalview. If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ */
+package jalview.datamodel;
+
+import java.util.Enumeration;
+import java.util.Vector;
+
+import jalview.util.MapList;
+
+/**
+ * Stores mapping between the columns of a protein alignment and a DNA alignment
+ * and a list of individual codon to amino acid mappings between sequences.
+ */
+
+public class AlignedCodonFrame
+{
+ /**
+ * array of nucleotide positions for aligned codons at column of aligned
+ * proteins.
+ */
+ public int[][] codons = null;
+
+ /**
+ * width of protein sequence alignement implicit assertion that codons.length
+ * >= aaWidth
+ */
+ public int aaWidth = 0;
+
+ /**
+ * initialise codon frame with a nominal alignment width
+ *
+ * @param aWidth
+ */
+ public AlignedCodonFrame(int aWidth)
+ {
+ if (aWidth <= 0)
+ {
+ codons = null;
+ return;
+ }
+ codons = new int[aWidth][];
+ for (int res = 0; res < aWidth; res++)
+ codons[res] = null;
+ }
+
+ /**
+ * ensure that codons array is at least as wide as aslen residues
+ *
+ * @param aslen
+ * @return (possibly newly expanded) codon array
+ */
+ public int[][] checkCodonFrameWidth(int aslen)
+ {
+ if (codons.length <= aslen + 1)
+ {
+ // probably never have to do this ?
+ int[][] c = new int[codons.length + 10][];
+ for (int i = 0; i < codons.length; i++)
+ {
+ c[i] = codons[i];
+ codons[i] = null;
+ }
+ codons = c;
+ }
+ return codons;
+ }
+
+ /**
+ * @return width of aligned translated amino acid residues
+ */
+ public int getaaWidth()
+ {
+ return aaWidth;
+ }
+
+ /**
+ * TODO: not an ideal solution - we reference the aligned amino acid sequences
+ * in order to make insertions on them Better would be dnaAlignment and
+ * aaAlignment reference....
+ */
+ Vector a_aaSeqs = new Vector();
+
+ /**
+ * increase aaWidth by one and insert a new aligned codon position space at
+ * aspos.
+ *
+ * @param aspos
+ */
+ public void insertAAGap(int aspos, char gapCharacter)
+ {
+ // this aa appears before the aligned codons at aspos - so shift them in
+ // each pair of mapped sequences
+ aaWidth++;
+ if (a_aaSeqs != null)
+ {
+ // we actually have to modify the aligned sequences here, so use the
+ // a_aaSeqs vector
+ Enumeration sq = a_aaSeqs.elements();
+ while (sq.hasMoreElements())
+ {
+ ((SequenceI) sq.nextElement()).insertCharAt(aspos, gapCharacter);
+ }
+ }
+ checkCodonFrameWidth(aspos);
+ if (aspos < aaWidth)
+ {
+ aaWidth++;
+ System.arraycopy(codons, aspos, codons, aspos + 1, codons.length - aspos - 1);
+ codons[aspos] = null; // clear so new codon position can be marked.
+ }
+ }
+
+ public void setAaWidth(int aapos)
+ {
+ aaWidth = aapos;
+ }
+
+ /**
+ * tied array of na Sequence objects.
+ */
+ SequenceI[] dnaSeqs = null;
+
+ /**
+ * tied array of Mappings to protein sequence Objects and SequenceI[]
+ * aaSeqs=null; MapLists where eac maps from the corresponding dnaSeqs element
+ * to corresponding aaSeqs element
+ */
+ Mapping[] dnaToProt = null;
+
+ /**
+ * add a mapping between the dataset sequences for the associated dna and
+ * protein sequence objects
+ *
+ * @param dnaseq
+ * @param aaseq
+ * @param map
+ */
+ public void addMap(SequenceI dnaseq, SequenceI aaseq, MapList map)
+ {
+ int nlen = 1;
+ if (dnaSeqs != null)
+ {
+ nlen = dnaSeqs.length + 1;
+ }
+ SequenceI[] ndna = new SequenceI[nlen];
+ Mapping[] ndtp = new Mapping[nlen];
+ if (dnaSeqs != null)
+ {
+ System.arraycopy(dnaSeqs, 0, ndna, 0, dnaSeqs.length);
+ System.arraycopy(dnaToProt, 0, ndtp, 0, dnaSeqs.length);
+ }
+ dnaSeqs = ndna;
+ dnaToProt = ndtp;
+ nlen--;
+ dnaSeqs[nlen] = (dnaseq.getDatasetSequence() == null) ? dnaseq : dnaseq
+ .getDatasetSequence();
+ Mapping mp = new Mapping(map);
+ // JBPNote DEBUG! THIS !
+ // dnaseq.transferAnnotation(aaseq, mp);
+ // aaseq.transferAnnotation(dnaseq, new Mapping(map.getInverse()));
+ mp.to = (aaseq.getDatasetSequence() == null) ? aaseq : aaseq
+ .getDatasetSequence();
+ a_aaSeqs.addElement(aaseq);
+ dnaToProt[nlen] = mp;
+ }
+
+ public SequenceI[] getdnaSeqs()
+ {
+ return dnaSeqs;
+ }
+
+ public SequenceI[] getAaSeqs()
+ {
+ if (dnaToProt == null)
+ return null;
+ SequenceI[] sqs = new SequenceI[dnaToProt.length];
+ for (int sz = 0; sz < dnaToProt.length; sz++)
+ {
+ sqs[sz] = dnaToProt[sz].to;
+ }
+ return sqs;
+ }
+
+ public MapList[] getdnaToProt()
+ {
+ if (dnaToProt == null)
+ return null;
+ MapList[] sqs = new MapList[dnaToProt.length];
+ for (int sz = 0; sz < dnaToProt.length; sz++)
+ {
+ sqs[sz] = dnaToProt[sz].map;
+ }
+ return sqs;
+ }
+
+ public Mapping[] getProtMappings()
+ {
+ return dnaToProt;
+ }
+
+ /**
+ *
+ * @param sequenceRef
+ * @return null or corresponding aaSeq entry for dnaSeq entry
+ */
+ public SequenceI getAaForDnaSeq(SequenceI dnaSeqRef)
+ {
+ if (dnaSeqs == null)
+ {
+ return null;
+ }
+ SequenceI dnads = dnaSeqRef.getDatasetSequence();
+ for (int ds = 0; ds < dnaSeqs.length; ds++)
+ {
+ if (dnaSeqs[ds] == dnaSeqRef || dnaSeqs[ds] == dnads)
+ return dnaToProt[ds].to;
+ }
+ return null;
+ }
+
+ /**
+ *
+ * @param sequenceRef
+ * @return null or corresponding aaSeq entry for dnaSeq entry
+ */
+ public SequenceI getDnaForAaSeq(SequenceI aaSeqRef)
+ {
+ if (dnaToProt == null)
+ {
+ return null;
+ }
+ SequenceI aads = aaSeqRef.getDatasetSequence();
+ for (int as = 0; as < dnaToProt.length; as++)
+ {
+ if (dnaToProt[as].to == aaSeqRef || dnaToProt[as].to == aads)
+ return dnaSeqs[as];
+ }
+ return null;
+ }
+
+ /**
+ * test to see if codon frame involves seq in any way
+ *
+ * @param seq
+ * a nucleotide or protein sequence
+ * @return true if a mapping exists to or from this sequence to any translated
+ * sequence
+ */
+ public boolean involvesSequence(SequenceI seq)
+ {
+ return getAaForDnaSeq(seq) != null || getDnaForAaSeq(seq) != null;
+ }
+
+ /**
+ * Add search results for regions in other sequences that translate or are
+ * translated from a particular position in seq
+ *
+ * @param seq
+ * @param index
+ * position in seq
+ * @param results
+ * where highlighted regions go
+ */
+ public void markMappedRegion(SequenceI seq, int index,
+ SearchResults results)
+ {
+ if (dnaToProt == null)
+ {
+ return;
+ }
+ int[] codon;
+ SequenceI ds = seq.getDatasetSequence();
+ for (int mi = 0; mi < dnaToProt.length; mi++)
+ {
+ if (dnaSeqs[mi] == seq || dnaSeqs[mi] == ds)
+ {
+ // DEBUG System.err.println("dna pos "+index);
+ codon = dnaToProt[mi].map.locateInTo(index, index);
+ if (codon != null)
+ {
+ for (int i = 0; i < codon.length; i += 2)
+ {
+ results.addResult(dnaToProt[mi].to, codon[i], codon[i + 1]);
+ }
+ }
+ }
+ else if (dnaToProt[mi].to == seq || dnaToProt[mi].to == ds)
+ {
+ // DEBUG System.err.println("aa pos "+index);
+ {
+ codon = dnaToProt[mi].map.locateInFrom(index, index);
+ if (codon != null)
+ {
+ for (int i = 0; i < codon.length; i += 2)
+ {
+ results.addResult(dnaSeqs[mi], codon[i], codon[i + 1]);
+ }
+ }
+ }
+ }
+ }
+ }
+}