X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=help%2Fhtml%2FwhatsNew.html;h=0abd2a7b9501e9f1fffc3bc4456f39ec4af1d50a;hb=0e684f72690bd6532272a39ab6c188a27559fd09;hp=448430d6afa3682fefa553af124b0750b0df2a49;hpb=448a82c6838c231172078210cfb1bdad138d4604;p=jalview.git diff --git a/help/html/whatsNew.html b/help/html/whatsNew.html index 448430d..0abd2a7 100755 --- a/help/html/whatsNew.html +++ b/help/html/whatsNew.html @@ -24,70 +24,27 @@

- What's new in Jalview 2.10.0b1 ? + What's new in Jalview 2.10.4 ?

- Jalview 2.10.0b1 is a patch release for 2.10, the next major release - in the Jalview 2 series. Full details are in the Jalview 2.10b1 Release - Notes, but the highlights are below. + This is the May 2018 release of Jalview, and the last in the 2.10.x series. Jalview 2.10.4 includes:

Drag and drop reinstated for the Jalview desktop on - Windows, Linux and older OSX systems.
Problems loading local PDB files have been fixed
Conservation shading can be disabled for PID and consensus - based colour scheme
Numerous efficiency improvements in the renderer and overview when working with large alignments with lots of hidden columns
Use of HTTPS when connecting to Uniprot, Ensembl and other EBI web services
Critical patches for running Jalview on OSX with Java 10
Easier adjustment of the Alignment ID panel and Annotation panel
Improved support for mapping between 3D Structures and Uniprot Protein Sequences
Improved support for discovering CDS and transcripts for Proteins and Ensembl gene IDs
New buttons on the Structure Chooser for adding structures + to an existing view, and disabling automatic superposition + according to linked alignments
Annotation transfer between Chimera and Jalview (formerly only + available in 'Experimental' mode)

Major highlights of the 2.10.0 Release

Ensembl sequence fetcher
Annotated - Genes, transcripts and proteins can be retrieved via Jalview's new - Ensembl REST - client. Support for import of Ensembl data allows: -
- Aligned locus view
  Transcripts - retrieved for a gene identifier via the Ensembl or - EnsemblGenomes sequence databases are automatically aligned to - their reference genome, and introns hidden from the view.
- Sequence variant data
  Jalview - propagates variant annotation on genomic regions onto - transcripts and protein products, complete with associated - metadata such as clinical significance.
Ensembl and ENA 'show cross-references' - support
The Calculations menu's 'Show - cross-references' now offers Ensembl as well as EMBLCDS and - Uniprot when CDS/Protein mapping data is available for download or - display. This allows variant annotation to be added directly to an - alignment of UniProt sequences.
Working with structures -
- More accurate structure mappings
  - Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI) - to match structures - to UniProt sequences, even for structures containing - multiple copies of a sequence.
- Import structures as mmCIF
  Jalview - now downloads data from the EMBL-EBI's PDBe site as mmCIF. This allows very large - structures to be imported, such as the HIV virus capsid - assembly.
- Chimera users will need to upgrade to - 1.11.1
  If you use Chimera to view structures - downloaded by Jalview 2.10, you will need to make sure you are - running the latest version of Chimera.
UniProt Free Text Search
The new - search dialog for UniProt allows you to browse and retrieve - sequences with free-text search, or structured queries.
Reference sequence alignment view
- Jalview 2.9 introduced support for reference sequences. In 2.10, - when a reference sequence is defined for the alignment, the - alignment column ruler is now numbered according to the reference - sequence. The reference sequence for alignment views can also be - saved and restored from Jalview projects.

- +

+ The full list of bugs fixed in this release can be found in the 2.10.4 + Release Notes. +