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What's new ?
-
- What's new ?
- Jalview 2.8 includes a number of enhancements and new features that
- have been in development since July 2010. It is also the first Jalview
- release to incorporate RNA visualization features developed by Lauren
- Lui and Jan Engelhart during their Google Summer of Code projects
- (http://code.google.com/soc/). As usual you can find the highlights
- below, but to see the comprehensive list take a look at the look at
- the Jalview 2.8 Release Notes.
-
- Highlights in Jalview Version 2.8
-
- - Improved JABAWS
- client and new JABAWS 2.0 Services
-
-
- - RNA
-
- - Import sequence and alignment associated WUSS or VIENNA
- dot-bracket notation from files and the RFAM
- database
-
- - Interactive editing of RNA secondary structure annotation
- - Colour scheme for purine/pyrimidine and to highlight RNA
- helices
- - RNA canonical base pair consensus
- score and sequence logo
-
- - Embedded VARNA RNA
- secondary structure viewer in the Desktop
-
-
- - Parse and display T-COFFEE
- alignment quality scores (thanks to Paolo di Tomasso of the Notredame
- Group)
-
- - Per
- sequence alignment annotation shading
- - Enhanced PCA viewer: more
- export options, and switch between different PCA modes and residue
- score models
-
- - New Jalview Desktop database
- fetcher GUI
-
- - Support for DAS 1.6 and DAS 2.0 sources (thanks to the new
- JDAS Distributed Annotation client library (see
- http://code.google.com/p/jdas))
- - Export sequence database annotation as an HTML report
- - Normalised Sequence
- Logo Display
-
-
- Issues resolved in the Jalview Desktop
-
-
- - PDB, Unprot and EMBL (ENA) databases retrieved via wsdbfetch
- REST service
- - Stop windows being moved outside desktop on OSX
- - Jnet job queues forever if a very short sequence is submitted
- for prediction
- - Structure view highlighting doesn't work on windows 7
- - Jalview desktop fails to launch with exception when using
- proxy
- - DAS Sequence retrieval with range qualification results in
- sequence xref which includes range qualification
- - Cannot close news reader when JABAWS server warning dialog is
- shown
- - Edited sequence not submitted to web service
- - Jalview 2.7 InstallAnywhere installer doesn't unpack and run
- on OSX Mountain Lion
-
- - If you use webstart then you may need to go into the
- Security panel (a.k.a the gatekeeper) in your System
- Settings, and select the 'allow any code to run' option.
-
-
-
-
-
- Issues specific to the JalviewLite Applet
-
-
- - Sequence features are momentarily displayed before they are
- hidden using hidefeaturegroups applet parameter
- - loading features via javascript API automatically enables
- feature display
- - scrollToColumnIn javascript API method doesn't work
-
-
- Issues affecting both applet and application
-
-
- - Redundancy removal fails for rna alignment
- - PCA window shows grey box when first opened on OSX
- - Letters coloured pink in sequence logo when alignment
- coloured with clustalx
-
+
+ What's new in Jalview 2.10.0b1 ?
+
+
+ Jalview 2.10.0b1 is a patch release for 2.10, the next major release
+ in the Jalview 2 series. Full details are in the Jalview 2.10b1 Release
+ Notes, but the highlights are below.
+
+
+ - Drag and drop reinstated for the Jalview desktop on
+ Windows, Linux and older OSX systems.
+ - Problems loading local PDB files have been fixed
+ - Conservation shading can be disabled for PID and consensus
+ based colour scheme
+
+ Major highlights of the 2.10.0 Release
+
+ - Ensembl sequence fetcher
Annotated
+ Genes, transcripts and proteins can be retrieved via Jalview's new
+ Ensembl REST
+ client. Support for import of Ensembl data allows:
+
+ - Aligned locus view
Transcripts
+ retrieved for a gene identifier via the Ensembl or
+ EnsemblGenomes sequence databases are automatically aligned to
+ their reference genome, and introns hidden from the view.
+ - Sequence variant data
Jalview
+ propagates variant annotation on genomic regions onto
+ transcripts and protein products, complete with associated
+ metadata such as clinical significance.
+
+ - Ensembl and ENA 'show cross-references'
+ support
The Calculations menu's 'Show
+ cross-references' now offers Ensembl as well as EMBLCDS and
+ Uniprot when CDS/Protein mapping data is available for download or
+ display. This allows variant annotation to be added directly to an
+ alignment of UniProt sequences.
+ - Working with structures
+
+ - More accurate structure mappings
+ Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI)
+ to match structures
+ to UniProt sequences, even for structures containing
+ multiple copies of a sequence.
+ - Import structures as mmCIF
Jalview
+ now downloads data from the EMBL-EBI's PDBe site as mmCIF. This allows very large
+ structures to be imported, such as the HIV virus capsid
+ assembly.
+ - Chimera users will need to upgrade to
+ 1.11.1
If you use Chimera to view structures
+ downloaded by Jalview 2.10, you will need to make sure you are
+ running the latest version of Chimera.
+
+ - UniProt Free Text Search
The new
+ search dialog for UniProt allows you to browse and retrieve
+ sequences with free-text search, or structured queries.
+ - Reference sequence alignment view
+ Jalview 2.9 introduced support for reference sequences. In 2.10,
+ when a reference sequence is defined for the alignment, the
+ alignment column ruler is now numbered according to the reference
+ sequence. The reference sequence for alignment views can also be
+ saved and restored from Jalview projects.
+
+