X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=help%2Fhtml%2FwhatsNew.html;h=8a0436dd0e6c35df296aefaed837cf04b8ff0f65;hb=cfa90577b4ddcb2e163a9bac0b2786d45de57933;hp=545d55b9a780c803a92270b8e96bcbd50176585e;hpb=4497a70ab5bf22b6b6a16c723949625fcca4845b;p=jalview.git
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- What's new ?
+ What's new in Jalview 2.10.2 ?
- Jalview 2.10 is the next major release in the Jalview 2 series. Full
- details are in the Jalview
- 2.10 Release Notes, but the highlights are below.
+ Full details about Jalview 2.10.2 are in the Release Notes, but the
+ highlights are below.
-
- Highlights in Jalview 2.10
- - Ensembl sequence fetcher. Annotated Genes,
- transcripts and proteins can be retrieved via Jalview's new Ensembl REST
- client. Support for import of Ensembl data allows:
-
- - Sequence variant data. Jalview
- propagates variant annotation on genomic regions onto transcripts and
- protein products, complete with associated metadata such as
- clinical significance.
- - Aligned locus view. Transcripts
- retrieved for a gene identifier via the Ensembl or
- EnsemblGenomes sequence databases are automatically aligned to
- their reference genome, and introns hidden from the view.
-
- - Working with structures.
+
- New UI, and faster and more configurable implementation for PCA, Neighbour-Joining and UPGMA Trees
+ Menu entries for calculating PCA and different types of tree have
+ been replaced by a single Calculations dialog box. The
+ underlying implementation for the PCA and tree calculations have been
+ made faster and more memory efficient. A new framework has also been
+ created for the score models used to calculate distances between
+ sequences. This framework allows import of substitution matrices in
+ NCBI and AAIndex format, and custom score models to be created via a
+ groovy script.
+ - Update to JABAWS 2.2
Jalview's
+ alignment, protein conservation analysis, and protein disorder and
+ RNA secondary structure prediction services are now provided by JABAWS 2.2.
+ Several of the programs provided as services have been updated, so
+ their options and parameters have changed.
+ - New preferences for opening
+ web pages for database cross-references via the UK Elixir's
+ EMBL-EBI's MIRIAM database and identifiers.org services.
+
+ - Showing and hiding regions
- - More accurate structure mappings.
- Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI)
- to match structures
- to UniProt sequences, even for structures containing
- multiple copies of a sequence.
- - Import structures as mmCIF. Jalview
-
- Chimera users will need to upgrade to
- 1.11.1.If you use Chimera to view structures downloaded by
- Jalview 2.10, you will need to make sure you are running the
- latest version of Chimera.
- now downloads data from the EMBL-EBI's PDBe site as mmCIF.
- This allows very large structures to be imported, such as the HIV virus capsid assembly.
+ - Hide
+ insertions in the PopUp menu has changed its behaviour.
+ Prior to 2.10.2, columns were only shown or hidden according
+ to gaps in the sequence under the popup menu. Now, only
+ columns that are gapped in all selected sequences as well as
+ the sequence under the popup menu are hidden, and column
+ visibility outside the selected region is left as is. This
+ makes it easy to filter insertions from the alignment view
+ (just select the region containing insertions to remove)
+ without affecting the rest of the hidden columns.
- UniProt Free Text Search. The new search
- dialog for UniProt allows you to browse and retrieve sequences
- from UniProt with free-text search and more structured queries
- Reference sequence alignment view..
- Jalview 2.9 introduced support for reference sequences. In 2.10,
- when a reference sequence is defined for the alignment, the
- alignment column ruler is now numbered according to the reference
- sequence. The reference sequence for alignment views can also be
- saved and restored from Jalview projects.
- Ensembl and ENA 'show cross-references'
- support.The Calculations menu's 'Show cross-references' will now
- offer Ensembl as well as EMBLCDS and Uniprot when CDS/Protein
- mapping data is available for download or display.
-
+
+ Experimental Features
+
+
+ This release of Jalview includes a new option in the Jalview Desktop
+ that allows you to try out features that are still in development.
+ To access the features described below, please first enable the Tools→Enable
+ Experimental Features option, and then restart Jalview.
+
+