The RNAalifold client was implemented by Jalview's 2013 - summer student, Dan Barton. -
- What's new ?
+ What's new ? + +
+ Jalview 2.8.2 is the first release produced by our new core
+ development team.
It incorporates many minor improvements and
+ bug-fixes, and new features for working with 3D structure data,
+ shading alignments by secondary structure and generation of alignment
+ figures as Scalable Vector Graphics.
The majority of
+ improvements in this version of Jalview concern the desktop
+ application. As ever, the highlights are detailed below,
+ and the full list is given in the Jalview 2.8.2 Release Notes.
+
- Jalview 2.8.1 includes new features for group creation, RNA secondary
- structure prediction and a host bug fixes. It also includes support
- for version 2.1
- of JABA and includes a Spanish translation of its user interface.
- The highlights are detailed below, and the full list is given in the Jalview 2.8.1 Release Notes.
+ Annotation visualisation
The alignment window
+ includes a new Annotations menu which provides controls for
+ the layout and display of sequence, group and alignment associated
+ annotation rows. It also now includes the Autocalculated
+ Annotation submenu (formerly located in the View menu), which
+ includes settings for the calculation and display of sequence
+ consensus, logos, and amino acid conservation for the alignment and
+ subgroups.
The Desktop and web based applet include new keystrokes for - defining and undefining groups, and PAM250 has been added to the range - of score models available for use by the tree and PCA calculations. - The Jalview project file format has also been extended for handling - RNA and protein secondary structure annotation, in anticipation for - new structure based secondary structure support in Jalview 2.8.2.
-Internationalisation
-Jalview 2.8.1 is the first release to include support for - displaying Jalview's user interface in different languages. In August - 2013, David Roldán-Martinez took on the task of - internationalising Jalview's user interface. He also recruited Sara - Hernández Díaz and Laura Ferrandis Martinez who created - Jalview's first spanish user interface translation.
- If you notice any problems, or would like to help translate Jalview's
- user interface into other languages, head over to issues.jalview.org and put in a
- feature request describing the translations you can provide to the i18n
- component. David has also documented
- the process of creating i18n translations to help you get started.
+ Sequence associated annotation
New controls
+ have also been added to the Sequence ID popup menu for the propagation
+ and display of sequence associated annotation such as secondary
+ structure assignments and disorder predictions. Annotation associated
+ with one or a group of sequence already shown on the alignment may be
+ shown or hidden, and any available annotation from 3D structure or
+ calculations performed in other Jalview windows can be copied to the
+ alignment
+ via the Add Reference Annotation option.
+ The Colour by annotation function has also been
+ improved, allowing secondary structure annotation to be used to shade
+ sequences and alignment columns. Protein sequences can be coloured
+ according to the presence of a helix or sheet at each position, and
+ RNA sequences can be shaded according to each structure's stem/helix
+ pattern - which enables different RNA folding topologies to be quickly
+ identified.
RNA Secondary Structure Prediction with JABA 2.1
- This version of Jalview includes a client to access the new services available in JABA v2.1 , which - provides services for RNA consensus secondary structure prediction and - two new alignment programs (GLProbs and MSAProbs).
+ 3D Structural data analysis and display
+ Interoperation with UCSF Chimera
The desktop
+ application can now be configured to employ UCSF Chimera for the
+ display of 3D structure data. UCSF Chimera is a python-based
+ high-performance molecular graphics and animation system developed by
+ the Resource for Biocomputing, Visualisation, and Informatics at the
+ University of California.
Jalview employs the 'StructureViz'
+ communication mechanism developed for Cytoscape by Morris et al.
+ (http://www.ncbi.nlm.nih.gov/pubmed/17623706) in 2007. This mechanism
+ allows Jalview to send commands to Chimera, enabling structures to be
+ superimposed and shaded according to associated multiple aligmment
+ views.
Support for Chimera in Jalview 2.8.2 is experimental, and we
+ would appreciate feedback ! Please send your comments to
+ jalview-discuss@jalview.org, and keep up to date with this feature's
+ development via http://issues.jalview.org/browse/JAL-1333.
+
- To see how to perform RNA secondary structure predictions like the one below, take a look at the RNAAliFold
- client documentation.
+ Export of alignment figures as Scalable Vector
+ Graphics
Scalable Vector Graphics (SVG) files are now widely
+ supported by web browsers and graphics design programs, and allow
+ high-quality graphics for interactive exploration and publication.
+ Jalview now supports the generation of SVGs interactively (via the
+ Export) menu, and from the command line for server-side figure
+ generation.