X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fext%2Fensembl%2FEnsemblCdna.java;h=e01ad17eaee377a850713e5af6e8fd47582859f1;hb=1f3cf1db69c97ace5c0606e2ee0ccbf569970761;hp=9c88b7c5215130094cc18759450517a8fa04561e;hpb=409fd993c6e32e999b24082aae107a043a590f8f;p=jalview.git

diff --git a/src/jalview/ext/ensembl/EnsemblCdna.java b/src/jalview/ext/ensembl/EnsemblCdna.java
index 9c88b7c..e01ad17 100644
--- a/src/jalview/ext/ensembl/EnsemblCdna.java
+++ b/src/jalview/ext/ensembl/EnsemblCdna.java
@@ -1,17 +1,78 @@
+/*
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
+ * 
+ * This file is part of Jalview.
+ * 
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License 
+ * as published by the Free Software Foundation, either version 3
+ * of the License, or (at your option) any later version.
+ *  
+ * Jalview is distributed in the hope that it will be useful, but 
+ * WITHOUT ANY WARRANTY; without even the implied warranty 
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
+ * PURPOSE.  See the GNU General Public License for more details.
+ * 
+ * You should have received a copy of the GNU General Public License
+ * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ */
 package jalview.ext.ensembl;
 
-import jalview.ext.ensembl.SeqFetcher.EnsemblSeqType;
+import jalview.datamodel.SequenceFeature;
+import jalview.datamodel.SequenceI;
+import jalview.io.gff.SequenceOntologyI;
+
+import java.util.ArrayList;
+import java.util.List;
 
 import com.stevesoft.pat.Regex;
 
+/**
+ * A client to fetch CDNA sequence from Ensembl (i.e. that part of the genomic
+ * sequence that is transcribed to RNA, but not necessarily translated to
+ * protein)
+ * 
+ * @author gmcarstairs
+ *
+ */
 public class EnsemblCdna extends EnsemblSeqProxy
 {
+  /*
+   * accepts ENST or ENSTG with 11 digits
+   * or ENSMUST or similar for other species
+   * or CCDSnnnnn.nn with at least 3 digits
+   */
+  private static final Regex ACCESSION_REGEX = new Regex(
+          "(ENS([A-Z]{3}|)[TG][0-9]{11}$)" + "|" + "(CCDS[0-9.]{3,}$)");
+
+  /*
+   * fetch exon features on genomic sequence (to identify the cdna regions)
+   * and cds and variation features (to retain)
+   */
+  private static final EnsemblFeatureType[] FEATURES_TO_FETCH = {
+      EnsemblFeatureType.exon, EnsemblFeatureType.cds,
+      EnsemblFeatureType.variation };
 
+  /**
+   * Default constructor (to use rest.ensembl.org)
+   */
   public EnsemblCdna()
   {
     super();
   }
 
+  /**
+   * Constructor given the target domain to fetch data from
+   * 
+   * @param d
+   */
+  public EnsemblCdna(String d)
+  {
+    super(d);
+  }
+
   @Override
   public String getDbName()
   {
@@ -27,13 +88,61 @@ public class EnsemblCdna extends EnsemblSeqProxy
   @Override
   public Regex getAccessionValidator()
   {
-    return new Regex("((ENST|ENSG|CCDS)[0-9.]{3,})");
+    return ACCESSION_REGEX;
+  }
+
+  @Override
+  protected EnsemblFeatureType[] getFeaturesToFetch()
+  {
+    return FEATURES_TO_FETCH;
+  }
+
+  /**
+   * Answers true unless the feature type is 'transcript' (or a sub-type in the
+   * Sequence Ontology).
+   */
+  @Override
+  protected boolean retainFeature(SequenceFeature sf, String accessionId)
+  {
+    if (isTranscript(sf.getType()))
+    {
+      return false;
+    }
+    return featureMayBelong(sf, accessionId);
+  }
+
+  /**
+   * Answers a list of sequence features (if any) whose type is 'exon' (or a
+   * subtype of exon in the Sequence Ontology), and whose Parent is the
+   * transcript we are retrieving
+   */
+  @Override
+  protected List<SequenceFeature> getIdentifyingFeatures(SequenceI seq,
+          String accId)
+  {
+    List<SequenceFeature> result = new ArrayList<>();
+    List<SequenceFeature> sfs = seq.getFeatures()
+            .getFeaturesByOntology(SequenceOntologyI.EXON);
+    for (SequenceFeature sf : sfs)
+    {
+      String parentFeature = (String) sf.getValue(PARENT);
+      if (accId.equals(parentFeature))
+      {
+        result.add(sf);
+      }
+    }
+
+    return result;
   }
 
+  /**
+   * Parameter object_type=Transcaript added to ensure cdna and not peptide is
+   * returned (JAL-2529)
+   */
   @Override
-  public String getTestQuery()
+  protected String getObjectType()
   {
-    return "ENST00000288602";
+    return OBJECT_TYPE_TRANSCRIPT;
   }
 
 }