X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fext%2Fensembl%2FEnsemblRestClient.java;h=24375886005dce6264b763e5dc6f12fdb0ebba2c;hb=136c0793b90b72b928c4d77dc109dd5c644e00d3;hp=6a564f10e9655a90f91cc5a9f0fa35d27f12b9ff;hpb=d547268f85f377f14dbeb169072caebad45f9e2b;p=jalview.git diff --git a/src/jalview/ext/ensembl/EnsemblRestClient.java b/src/jalview/ext/ensembl/EnsemblRestClient.java index 6a564f1..2437588 100644 --- a/src/jalview/ext/ensembl/EnsemblRestClient.java +++ b/src/jalview/ext/ensembl/EnsemblRestClient.java @@ -1,6 +1,28 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ package jalview.ext.ensembl; +import jalview.io.DataSourceType; import jalview.io.FileParse; +import jalview.util.StringUtils; import java.io.BufferedReader; import java.io.DataOutputStream; @@ -10,10 +32,16 @@ import java.io.InputStreamReader; import java.net.HttpURLConnection; import java.net.MalformedURLException; import java.net.URL; +import java.util.HashMap; import java.util.List; +import java.util.Map; import javax.ws.rs.HttpMethod; +import org.json.simple.JSONArray; +import org.json.simple.JSONObject; +import org.json.simple.parser.JSONParser; + import com.stevesoft.pat.Regex; /** @@ -23,31 +51,48 @@ import com.stevesoft.pat.Regex; */ abstract class EnsemblRestClient extends EnsemblSequenceFetcher { - private final static String ENSEMBL_REST = "http://rest.ensembl.org"; + private static final int DEFAULT_READ_TIMEOUT = 5 * 60 * 1000; // 5 minutes + + private static final int CONNECT_TIMEOUT_MS = 10 * 1000; // 10 seconds + + /* + * update these constants when Jalview has been checked / updated for + * changes to Ensembl REST API (ref JAL-2105) + * @see https://github.com/Ensembl/ensembl-rest/wiki/Change-log + * @see http://rest.ensembl.org/info/rest?content-type=application/json + */ + private static final String LATEST_ENSEMBLGENOMES_REST_VERSION = "5.0"; + + private static final String LATEST_ENSEMBL_REST_VERSION = "5.0"; - protected final static String ENSEMBL_GENOMES_REST = "http://rest.ensemblgenomes.org"; + private static final String REST_CHANGE_LOG = "https://github.com/Ensembl/ensembl-rest/wiki/Change-log"; + + private static Map domainData; // @see https://github.com/Ensembl/ensembl-rest/wiki/Output-formats private static final String PING_URL = "http://rest.ensembl.org/info/ping.json"; - private final static long RETEST_INTERVAL = 10000L; // 10 seconds - - private static final Regex TRANSCRIPT_REGEX = new Regex( - "(ENS)([A-Z]{3}|)T[0-9]{11}$"); + private final static long AVAILABILITY_RETEST_INTERVAL = 10000L; // 10 seconds - private static final Regex GENE_REGEX = new Regex( - "(ENS)([A-Z]{3}|)G[0-9]{11}$"); + private final static long VERSION_RETEST_INTERVAL = 1000L * 3600; // 1 hr - private String domain = ENSEMBL_REST; + private static final Regex PROTEIN_REGEX = new Regex( + "(ENS)([A-Z]{3}|)P[0-9]{11}$"); - private static boolean ensemblRestAvailable = false; + private static final Regex TRANSCRIPT_REGEX = new Regex( + "(ENS)([A-Z]{3}|)T[0-9]{11}$"); - private static long lastCheck = -1; + private static final Regex GENE_REGEX = new Regex( + "(ENS)([A-Z]{3}|)G[0-9]{11}$"); - /* - * absolute time to wait till if we overloaded the REST service - */ - private static long retryAfter; + static + { + domainData = new HashMap(); + domainData.put(ENSEMBL_REST, new EnsemblInfo(ENSEMBL_REST, + LATEST_ENSEMBL_REST_VERSION)); + domainData.put(ENSEMBL_GENOMES_REST, new EnsemblInfo( + ENSEMBL_GENOMES_REST, LATEST_ENSEMBLGENOMES_REST_VERSION)); + } protected volatile boolean inProgress = false; @@ -66,35 +111,31 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher */ public EnsemblRestClient(String d) { - domain = d; + setDomain(d); } /** - * Returns the domain name to query e.g. http://rest.ensembl.org or - * http://rest.ensemblgenomes.org + * Answers true if the query matches the regular expression pattern for an + * Ensembl transcript stable identifier * + * @param query * @return */ - String getDomain() - { - return domain; - } - - void setDomain(String d) + public boolean isTranscriptIdentifier(String query) { - domain = d; + return query == null ? false : TRANSCRIPT_REGEX.search(query); } /** * Answers true if the query matches the regular expression pattern for an - * Ensembl transcript stable identifier + * Ensembl protein stable identifier * * @param query * @return */ - public boolean isTranscriptIdentifier(String query) + public boolean isProteinIdentifier(String query) { - return query == null ? false : TRANSCRIPT_REGEX.search(query); + return query == null ? false : PROTEIN_REGEX.search(query); } /** @@ -157,30 +198,47 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher protected abstract String getResponseMimeType(); /** - * Tries to connect to Ensembl's REST 'ping' endpoint, and returns true if - * successful, else false + * Checks Ensembl's REST 'ping' endpoint, and returns true if response + * indicates available, else false * + * @see http://rest.ensembl.org/documentation/info/ping * @return */ private boolean checkEnsembl() { + BufferedReader br = null; try { // note this format works for both ensembl and ensemblgenomes // info/ping.json works for ensembl only (March 2016) URL ping = new URL(getDomain() + "/info/ping?content-type=application/json"); - HttpURLConnection conn = (HttpURLConnection) ping.openConnection(); - int rc = conn.getResponseCode(); - conn.disconnect(); - if (rc >= 200 && rc < 300) - { - return true; - } + + /* + * expect {"ping":1} if ok + * if ping takes more than 2 seconds to respond, treat as if unavailable + */ + br = getHttpResponse(ping, null, 2 * 1000); + JSONParser jp = new JSONParser(); + JSONObject val = (JSONObject) jp.parse(br); + String pingString = val.get("ping").toString(); + return pingString != null; } catch (Throwable t) { System.err.println("Error connecting to " + PING_URL + ": " + t.getMessage()); + } finally + { + if (br != null) + { + try + { + br.close(); + } catch (IOException e) + { + // ignore + } + } } return false; } @@ -196,33 +254,55 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher throws IOException { URL url = getUrl(ids); - + BufferedReader reader = getHttpResponse(url, ids); - FileParse fp = new FileParse(reader, url.toString(), "HTTP_POST"); + if (reader == null) + { + // request failed + return null; + } + FileParse fp = new FileParse(reader, url.toString(), DataSourceType.URL); return fp; } /** + * Gets a reader to the HTTP response, using the default read timeout of 5 + * minutes + * + * @param url + * @param ids + * @return + * @throws IOException + */ + protected BufferedReader getHttpResponse(URL url, List ids) + throws IOException + { + return getHttpResponse(url, ids, DEFAULT_READ_TIMEOUT); + } + + /** * Writes the HTTP request and gets the response as a reader. * * @param url * @param ids * written as Json POST body if more than one + * @param readTimeout + * in milliseconds * @return * @throws IOException * if response code was not 200, or other I/O error */ - protected BufferedReader getHttpResponse(URL url, List ids) - throws IOException + protected BufferedReader getHttpResponse(URL url, List ids, + int readTimeout) throws IOException { // long now = System.currentTimeMillis(); HttpURLConnection connection = (HttpURLConnection) url.openConnection(); - + /* * POST method allows multiple queries in one request; it is supported for * sequence queries, but not for overlap */ - boolean multipleIds = ids.size() > 1;// useGetRequest(); + boolean multipleIds = ids != null && ids.size() > 1; connection.setRequestMethod(multipleIds ? HttpMethod.POST : HttpMethod.GET); connection.setRequestProperty("Content-Type", @@ -233,29 +313,33 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher connection.setDoInput(true); connection.setDoOutput(multipleIds); + connection.setConnectTimeout(CONNECT_TIMEOUT_MS); + connection.setReadTimeout(readTimeout); + if (multipleIds) { writePostBody(connection, ids); } - - InputStream response = connection.getInputStream(); + int responseCode = connection.getResponseCode(); - + if (responseCode != 200) { /* * note: a GET request for an invalid id returns an error code e.g. 415 * but POST request returns 200 and an empty Fasta response */ - throw new IOException( - "Response code was not 200. Detected response was " - + responseCode); + System.err.println("Response code " + responseCode + " for " + url); + return null; } + // get content + InputStream response = connection.getInputStream(); + // System.out.println(getClass().getName() + " took " // + (System.currentTimeMillis() - now) + "ms to fetch"); checkRateLimits(connection); - + BufferedReader reader = null; reader = new BufferedReader(new InputStreamReader(response, "UTF-8")); return reader; @@ -284,13 +368,14 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher // to test: // retryDelay = "5"; + EnsemblInfo info = domainData.get(getDomain()); if (retryDelay != null) { System.err.println("Ensembl REST service rate limit exceeded, wait " + retryDelay + " seconds before retrying"); try { - retryAfter = System.currentTimeMillis() + info.retryAfter = System.currentTimeMillis() + (1000 * Integer.valueOf(retryDelay)); } catch (NumberFormatException e) { @@ -300,46 +385,64 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher } else { - retryAfter = 0; + info.retryAfter = 0; // debug: // System.out.println(String.format( // "%s Ensembl requests remaining of %s (reset in %ss)", // remaining, limit, reset)); } } + /** * Rechecks if Ensembl is responding, unless the last check was successful and * the retest interval has not yet elapsed. Returns true if Ensembl is up, - * else false. + * else false. Also retrieves and saves the current version of Ensembl data + * and REST services at intervals. * * @return */ protected boolean isEnsemblAvailable() { + EnsemblInfo info = domainData.get(getDomain()); + long now = System.currentTimeMillis(); /* * check if we are waiting for 'Retry-After' to expire */ - if (retryAfter > now) + if (info.retryAfter > now) { - System.err.println("Still " + (1 + (retryAfter - now) / 1000) + System.err.println("Still " + (1 + (info.retryAfter - now) / 1000) + " secs to wait before retrying Ensembl"); return false; } else { - retryAfter = 0; + info.retryAfter = 0; } - boolean retest = now - lastCheck > RETEST_INTERVAL; - if (ensemblRestAvailable && !retest) + /* + * recheck if Ensembl is up if it was down, or the recheck period has elapsed + */ + boolean retestAvailability = (now - info.lastAvailableCheckTime) > AVAILABILITY_RETEST_INTERVAL; + if (!info.restAvailable || retestAvailability) { - return true; + info.restAvailable = checkEnsembl(); + info.lastAvailableCheckTime = now; } - ensemblRestAvailable = checkEnsembl(); - lastCheck = now; - return ensemblRestAvailable; + + /* + * refetch Ensembl versions if the recheck period has elapsed + */ + boolean refetchVersion = (now - info.lastVersionCheckTime) > VERSION_RETEST_INTERVAL; + if (refetchVersion) + { + checkEnsemblRestVersion(); + checkEnsemblDataVersion(); + info.lastVersionCheckTime = now; + } + + return info.restAvailable; } /** @@ -378,4 +481,105 @@ abstract class EnsemblRestClient extends EnsemblSequenceFetcher wr.close(); } + /** + * Fetches and checks Ensembl's REST version number + * + * @return + */ + private void checkEnsemblRestVersion() + { + EnsemblInfo info = domainData.get(getDomain()); + + JSONParser jp = new JSONParser(); + URL url = null; + try + { + url = new URL(getDomain() + + "/info/rest?content-type=application/json"); + BufferedReader br = getHttpResponse(url, null); + JSONObject val = (JSONObject) jp.parse(br); + String version = val.get("release").toString(); + String majorVersion = version.substring(0, version.indexOf(".")); + String expected = info.expectedRestVersion; + String expectedMajorVersion = expected.substring(0, + expected.indexOf(".")); + info.restMajorVersionMismatch = false; + try + { + /* + * if actual REST major version is ahead of what we expect, + * record this in case we want to warn the user + */ + if (Float.valueOf(majorVersion) > Float + .valueOf(expectedMajorVersion)) + { + info.restMajorVersionMismatch = true; + } + } catch (NumberFormatException e) + { + System.err.println("Error in REST version: " + e.toString()); + } + + /* + * check if REST version is later than what Jalview has tested against, + * if so warn; we don't worry if it is earlier (this indicates Jalview has + * been tested in advance against the next pending REST version) + */ + boolean laterVersion = StringUtils.compareVersions(version, expected) == 1; + if (laterVersion) + { + System.err + .println(String + .format("EnsemblRestClient expected %s REST version %s but found %s, see %s", + getDbSource(), expected, version, + REST_CHANGE_LOG)); + } + info.restVersion = version; + } catch (Throwable t) + { + System.err.println("Error checking Ensembl REST version: " + + t.getMessage()); + } + } + + public boolean isRestMajorVersionMismatch() + { + return domainData.get(getDomain()).restMajorVersionMismatch; + } + + /** + * Fetches and checks Ensembl's data version number + * + * @return + */ + private void checkEnsemblDataVersion() + { + JSONParser jp = new JSONParser(); + URL url = null; + try + { + url = new URL(getDomain() + + "/info/data?content-type=application/json"); + BufferedReader br = getHttpResponse(url, null); + JSONObject val = (JSONObject) jp.parse(br); + JSONArray versions = (JSONArray) val.get("releases"); + domainData.get(getDomain()).dataVersion = versions.get(0).toString(); + } catch (Throwable t) + { + System.err.println("Error checking Ensembl data version: " + + t.getMessage()); + } + } + + public String getEnsemblDataVersion() + { + return domainData.get(getDomain()).dataVersion; + } + + @Override + public String getDbVersion() + { + return getEnsemblDataVersion(); + } + }