X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fext%2Fhtsjdk%2FVCFReader.java;h=176b21dec490ab5d3239d09f00f46131a96fb2a4;hb=4e0bf08fc16e9388bb76cdd3eac84d767d102690;hp=14c057f7e56a23b195889473fe11d38cd04465de;hpb=f4766a7bbcfae845fc95923b01fa14ff83d589ff;p=jalview.git diff --git a/src/jalview/ext/htsjdk/VCFReader.java b/src/jalview/ext/htsjdk/VCFReader.java index 14c057f..176b21d 100644 --- a/src/jalview/ext/htsjdk/VCFReader.java +++ b/src/jalview/ext/htsjdk/VCFReader.java @@ -1,13 +1,34 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ package jalview.ext.htsjdk; +import java.io.Closeable; +import java.io.File; +import java.io.IOException; + import htsjdk.samtools.util.CloseableIterator; import htsjdk.variant.variantcontext.VariantContext; import htsjdk.variant.vcf.VCFFileReader; import htsjdk.variant.vcf.VCFHeader; - -import java.io.Closeable; -import java.io.File; -import java.io.IOException; +import jalview.bin.Console; /** * A thin wrapper for htsjdk classes to read either plain, or compressed, or @@ -19,36 +40,54 @@ public class VCFReader implements Closeable, Iterable private static final String TBI_EXTENSION = ".tbi"; + private static final String CSI_EXTENSION = ".csi"; + private boolean indexed; private VCFFileReader reader; /** - * Constructor given a raw or compressed VCF file or a (tabix) index file + * Constructor given a raw or compressed VCF file or a (csi or tabix) index + * file *

- * For now, file type is inferred from its suffix: .gz or .bgz for compressed - * data, .tbi for an index file, anything else is assumed to be plain text - * VCF. + * If the file path ends in ".tbi" or ".csi", or appending one of + * these extensions gives a valid file path, open as indexed, else as + * unindexed. * * @param f * @throws IOException */ public VCFReader(String filePath) throws IOException { - if (filePath.endsWith(GZ)) + indexed = false; + if (filePath.endsWith(TBI_EXTENSION) + || filePath.endsWith(CSI_EXTENSION)) { - if (new File(filePath + TBI_EXTENSION).exists()) - { - indexed = true; - } + indexed = true; + filePath = filePath.substring(0, filePath.length() - 4); } - else if (filePath.endsWith(TBI_EXTENSION)) + else if (new File(filePath + TBI_EXTENSION).exists()) + { + indexed = true; + } + else if (new File(filePath + CSI_EXTENSION).exists()) { indexed = true; - filePath = filePath.substring(0, filePath.length() - 4); } - reader = new VCFFileReader(new File(filePath), indexed); + /* + * we pass the name of the unindexed file to htsjdk, + * with a flag to assert whether it is indexed + */ + File file = new File(filePath); + if (file.exists()) + { + reader = new VCFFileReader(file, indexed); + } + else + { + Console.error("File not found: " + filePath); + } } @Override @@ -88,9 +127,10 @@ public class VCFReader implements Closeable, Iterable public CloseableIterator query(final String chrom, final int start, final int end) { - if (reader == null) { - return null; - } + if (reader == null) + { + return null; + } if (indexed) { return reader.query(chrom, start, end); @@ -115,7 +155,7 @@ public class VCFReader implements Closeable, Iterable final String chrom, final int start, final int end) { final CloseableIterator it = reader.iterator(); - + return new CloseableIterator() { boolean atEnd = false; @@ -145,7 +185,7 @@ public class VCFReader implements Closeable, Iterable int vend = variant.getEnd(); // todo what is the undeprecated way to get // the chromosome for the variant? - if (chrom.equals(variant.getChr()) && (vstart <= end) + if (chrom.equals(variant.getContig()) && (vstart <= end) && (vend >= start)) { return variant;