X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fio%2Fvcf%2FVCFLoader.java;h=f965c4e2d4b093381ac29514326681bec075044c;hb=dc24bc768061f6e08be77d7e18709da98c6f9428;hp=cbdd66c8af2f38e054f89fbb400bdbce51746760;hpb=3b3c59cfa50e942d2fa5b367b7117cade9459ce7;p=jalview.git diff --git a/src/jalview/io/vcf/VCFLoader.java b/src/jalview/io/vcf/VCFLoader.java index cbdd66c..f965c4e 100644 --- a/src/jalview/io/vcf/VCFLoader.java +++ b/src/jalview/io/vcf/VCFLoader.java @@ -1,26 +1,25 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ package jalview.io.vcf; -import jalview.analysis.Dna; -import jalview.api.AlignViewControllerGuiI; -import jalview.bin.Cache; -import jalview.datamodel.DBRefEntry; -import jalview.datamodel.GeneLociI; -import jalview.datamodel.Mapping; -import jalview.datamodel.SequenceFeature; -import jalview.datamodel.SequenceI; -import jalview.datamodel.features.FeatureAttributeType; -import jalview.datamodel.features.FeatureSource; -import jalview.datamodel.features.FeatureSources; -import jalview.ext.ensembl.EnsemblMap; -import jalview.ext.htsjdk.HtsContigDb; -import jalview.ext.htsjdk.VCFReader; -import jalview.io.gff.Gff3Helper; -import jalview.io.gff.SequenceOntologyI; -import jalview.util.MapList; -import jalview.util.MappingUtils; -import jalview.util.MessageManager; -import jalview.util.StringUtils; - import java.io.File; import java.io.IOException; import java.util.ArrayList; @@ -47,6 +46,26 @@ import htsjdk.variant.vcf.VCFHeaderLine; import htsjdk.variant.vcf.VCFHeaderLineCount; import htsjdk.variant.vcf.VCFHeaderLineType; import htsjdk.variant.vcf.VCFInfoHeaderLine; +import jalview.analysis.Dna; +import jalview.api.AlignViewControllerGuiI; +import jalview.bin.Cache; +import jalview.datamodel.DBRefEntry; +import jalview.datamodel.GeneLociI; +import jalview.datamodel.Mapping; +import jalview.datamodel.SequenceFeature; +import jalview.datamodel.SequenceI; +import jalview.datamodel.features.FeatureAttributeType; +import jalview.datamodel.features.FeatureSource; +import jalview.datamodel.features.FeatureSources; +import jalview.ext.ensembl.EnsemblMap; +import jalview.ext.htsjdk.HtsContigDb; +import jalview.ext.htsjdk.VCFReader; +import jalview.io.gff.Gff3Helper; +import jalview.io.gff.SequenceOntologyI; +import jalview.util.MapList; +import jalview.util.MappingUtils; +import jalview.util.MessageManager; +import jalview.util.StringUtils; /** * A class to read VCF data (using the htsjdk) and add variants as sequence @@ -654,13 +673,12 @@ public class VCFLoader /** * Transfers VCF features to sequences to which this sequence has a mapping. - * If the mapping is 3:1, computes peptide variants from nucleotide variants. * * @param seq */ protected void transferAddedFeatures(SequenceI seq) { - DBRefEntry[] dbrefs = seq.getDBRefs(); + List dbrefs = seq.getDBRefs(); if (dbrefs == null) { return; @@ -877,12 +895,19 @@ public class VCFLoader int[] featureRange = map.map.locateInFrom(variant.getStart(), variant.getEnd()); + /* + * only take features whose range is fully mappable to sequence positions + */ if (featureRange != null) { int featureStart = Math.min(featureRange[0], featureRange[1]); int featureEnd = Math.max(featureRange[0], featureRange[1]); - count += addAlleleFeatures(seq, variant, featureStart, - featureEnd, forwardStrand); + if (featureEnd - featureStart == variant.getEnd() + - variant.getStart()) + { + count += addAlleleFeatures(seq, variant, featureStart, + featureEnd, forwardStrand); + } } } variants.close(); @@ -892,7 +917,7 @@ public class VCFLoader * RuntimeException throwable by htsjdk */ String msg = String.format("Error reading VCF for %s:%d-%d: %s ", - map.chromosome, vcfStart, vcfEnd); + map.chromosome, vcfStart, vcfEnd,e.getLocalizedMessage()); Cache.log.error(msg); } }