X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Futil%2FComparison.java;h=0beb45bcefca1ad9319236dac9d93bd18af68636;hb=37de9310bec3501cbc6381e0c3dcb282fcaad812;hp=cec9bc365e70a1db5e38cba02c246e277ac0442c;hpb=59d682209891099d46b960509907c79e3fb276fe;p=jalview.git diff --git a/src/jalview/util/Comparison.java b/src/jalview/util/Comparison.java index cec9bc3..0beb45b 100644 --- a/src/jalview/util/Comparison.java +++ b/src/jalview/util/Comparison.java @@ -1,34 +1,47 @@ /* - * Jalview - A Sequence Alignment Editor and Viewer (Version 2.8) - * Copyright (C) 2012 J Procter, AM Waterhouse, LM Lui, J Engelhardt, G Barton, M Clamp, S Searle + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors * * This file is part of Jalview. * * Jalview is free software: you can redistribute it and/or * modify it under the terms of the GNU General Public License - * as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. * * Jalview is distributed in the hope that it will be useful, but * WITHOUT ANY WARRANTY; without even the implied warranty * of MERCHANTABILITY or FITNESS FOR A PARTICULAR * PURPOSE. See the GNU General Public License for more details. * - * You should have received a copy of the GNU General Public License along with Jalview. If not, see . + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. */ package jalview.util; -import jalview.datamodel.*; +import jalview.datamodel.SequenceI; + +import java.util.ArrayList; +import java.util.List; /** - * DOCUMENT ME! - * - * @author $author$ - * @version $Revision$ + * Assorted methods for analysing or comparing sequences. */ public class Comparison { - /** DOCUMENT ME!! */ - public static final String GapChars = " .-"; + private static final int EIGHTY_FIVE = 85; + + private static final int TO_UPPER_CASE = 'a' - 'A'; + + private static final char GAP_SPACE = ' '; + + private static final char GAP_DOT = '.'; + + private static final char GAP_DASH = '-'; + + public static final String GapChars = new String(new char[] { GAP_SPACE, + GAP_DOT, GAP_DASH }); /** * DOCUMENT ME! @@ -66,12 +79,12 @@ public class Comparison int ilen = si.length() - 1; int jlen = sj.length() - 1; - while (jalview.util.Comparison.isGap(si.charAt(start + ilen))) + while (Comparison.isGap(si.charAt(start + ilen))) { ilen--; } - while (jalview.util.Comparison.isGap(sj.charAt(start + jlen))) + while (Comparison.isGap(sj.charAt(start + jlen))) { jlen--; } @@ -222,47 +235,99 @@ public class Comparison } /** - * DOCUMENT ME! + * Answers true if the supplied character is a recognised gap character, else + * false. Currently hard-coded to recognise '-', '-' or ' ' (hyphen / dot / + * space). * * @param c - * DOCUMENT ME! * - * @return DOCUMENT ME! + * @return */ public static final boolean isGap(char c) { - return (c == '-' || c == '.' || c == ' ') ? true : false; + return (c == GAP_DASH || c == GAP_DOT || c == GAP_SPACE) ? true : false; } + /** + * Overloaded method signature to test whether a single sequence is nucleotide + * (that is, more than 85% CGTA) + * + * @param seq + * @return + */ + public static final boolean isNucleotide(SequenceI seq) + { + return isNucleotide(new SequenceI[] { seq }); + } + + /** + * Answers true if more than 85% of the sequence residues (ignoring gaps) are + * A, G, C, T or U, else false. This is just a heuristic guess and may give a + * wrong answer (as AGCT are also amino acid codes). + * + * @param seqs + * @return + */ public static final boolean isNucleotide(SequenceI[] seqs) { - int i = 0, iSize = seqs.length, j, jSize; - float nt = 0, aa = 0; - char c; - while (i < iSize) + if (seqs == null) { - jSize = seqs[i].getLength(); - for (j = 0; j < jSize; j++) + return false; + } + char[][] letters = new char[seqs.length][]; + for (int i = 0; i < seqs.length; i++) + { + if (seqs[i] != null) { - c = seqs[i].getCharAt(j); - if ('a' <= c && c <= 'z') + char[] sequence = seqs[i].getSequence(); + if (sequence != null) { - c -= ('a' - 'A'); + letters[i] = sequence; } + } + } + + return areNucleotide(letters); + } - if (c == 'A' || c == 'G' || c == 'C' || c == 'T' || c == 'U') + /** + * Answers true if more than 85% of the sequence residues (ignoring gaps) are + * A, G, C, T or U, else false. This is just a heuristic guess and may give a + * wrong answer (as AGCT are also amino acid codes). + * + * @param letters + * @return + */ + static final boolean areNucleotide(char[][] letters) + { + int ntCount = 0; + int aaCount = 0; + for (char[] seq : letters) + { + if (seq == null) + { + continue; + } + // TODO could possibly make an informed guess just from the first sequence + // to save a lengthy calculation + for (char c : seq) + { + if (isNucleotide(c)) { - nt++; + ntCount++; } - else if (!jalview.util.Comparison.isGap(seqs[i].getCharAt(j))) + else if (!isGap(c)) { - aa++; + aaCount++; } } - i++; } - if ((nt / (nt + aa)) > 0.85f) + /* + * Check for nucleotide count > 85% of total count (in a form that evades + * int / float conversion or divide by zero). + */ + if (ntCount * 100 > EIGHTY_FIVE * (ntCount + aaCount)) { return true; } @@ -272,4 +337,82 @@ public class Comparison } } + + /** + * Answers true if the character is one of aAcCgGtTuU + * + * @param c + * @return + */ + public static boolean isNucleotide(char c) + { + if ('a' <= c && c <= 'z') + { + c -= TO_UPPER_CASE; + } + + switch (c) + { + case 'A': + case 'C': + case 'G': + case 'T': + case 'U': + return true; + } + return false; + } + + /** + * Answers true if every character in the string is one of aAcCgGtTuU, or + * (optionally) a gap character (dot, dash, space), else false + * + * @param s + * @param allowGaps + * @return + */ + public static boolean isNucleotideSequence(String s, boolean allowGaps) + { + if (s == null) + { + return false; + } + for (int i = 0; i < s.length(); i++) + { + char c = s.charAt(i); + if (!isNucleotide(c)) + { + if (!allowGaps || !isGap(c)) + { + return false; + } + } + } + return true; + } + + /** + * Convenience overload of isNucleotide + * + * @param seqs + * @return + */ + public static boolean isNucleotide(SequenceI[][] seqs) + { + if (seqs == null) + { + return false; + } + List flattened = new ArrayList(); + for (SequenceI[] ss : seqs) + { + for (SequenceI s : ss) + { + flattened.add(s); + } + } + final SequenceI[] oneDArray = flattened.toArray(new SequenceI[flattened + .size()]); + return isNucleotide(oneDArray); + } }