X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=src%2Fjalview%2Fws%2Febi%2FHmmerJSONProcessor.java;h=428c4983406df1ed0bd12b129b6bf161413c1d98;hb=f3133c4f086cbdf59a7ce7fe465d2a5fa4a0fd60;hp=0aee45fb1a3b1a00d25b9b9e279f3ad678b80876;hpb=2159638c2d8e9cdcbebaf1e36e74cf2db73472cb;p=jalview.git diff --git a/src/jalview/ws/ebi/HmmerJSONProcessor.java b/src/jalview/ws/ebi/HmmerJSONProcessor.java index 0aee45f..428c498 100644 --- a/src/jalview/ws/ebi/HmmerJSONProcessor.java +++ b/src/jalview/ws/ebi/HmmerJSONProcessor.java @@ -4,10 +4,16 @@ import jalview.datamodel.AlignmentAnnotation; import jalview.datamodel.AlignmentI; import jalview.datamodel.Annotation; import jalview.datamodel.SequenceFeature; +import jalview.datamodel.SequenceGroup; import jalview.datamodel.SequenceI; import jalview.io.FileParse; +import jalview.viewmodel.AlignmentViewport; import java.io.IOException; +import java.util.ArrayList; +import java.util.HashMap; +import java.util.List; +import java.util.Map; import org.json.simple.JSONArray; import org.json.simple.JSONObject; @@ -15,8 +21,16 @@ import org.json.simple.parser.JSONParser; public class HmmerJSONProcessor { + /** + * result to be annotated. may not be null + */ AlignmentI resultAl; + /** + * viewport on the alignment. may be null at construction time + */ + AlignmentViewport viewAl = null; + public HmmerJSONProcessor(AlignmentI searchResult) { resultAl = searchResult; @@ -140,11 +154,16 @@ public class HmmerJSONProcessor .get("alimodel"), ppline = (String) dhit.get("alippline"); // int found = 0; + SequenceI firsthit = null; for (SequenceI hitseq : hits) { // match alisqfrom,alisqto,seq if (hitseq.getStart() == alisqfrom && hitseq.getEnd() == alisqto) { + if (found == 0) + { + firsthit = hitseq; + } found++; // annotated a sequence AlignmentAnnotation alipp = parsePosteriorProb(ppline); AlignmentAnnotation pval = new AlignmentAnnotation("p-value", @@ -158,12 +177,15 @@ public class HmmerJSONProcessor hitseq.addAlignmentAnnotation(eval); alipp.createSequenceMapping(hitseq, hitseq.getStart(), false); hitseq.addAlignmentAnnotation(alipp); + String arch; hitseq.addSequenceFeature(new SequenceFeature( "Pfam Domain Architecture", (hmmrhit.get("archindex")) - + " " - + (String) hmmrhit.get("arch"), 0, 0, Integer - .valueOf((String) hmmrhit.get("archScore")), + + " " + (arch = (String) hmmrhit.get("arch")), 0, + 0, + (hmmrhit.get("archScore") != null ? Integer + .valueOf((String) hmmrhit.get("archScore")) : 0f), "HMMER3")); + addArchGroup(hitseq, arch); alipp.setScore(Double.valueOf("" + dhit.get("bitscore"))); alipp.adjustForAlignment(); resultAl.addAnnotation(pval); @@ -172,19 +194,114 @@ public class HmmerJSONProcessor alipp.validateRangeAndDisplay(); } } - if (found == 0) + // look for other sequences represented by this hit and create rep groups + // could be in "pdbs", or .. + addRedundantSeqGroup(firsthit, alisqfrom, alisqto, + (JSONArray) hmmrhit.get("seqs"), true); + } + } + + /** + * series of operations to perform for the viewpanel associated with the + * alignment + */ + private List viewOps = new ArrayList(); + + public void updateView(AlignmentViewport view) + { + viewAl = view; + for (Runnable op : viewOps) + { + op.run(); + } + } + + private void addRedundantSeqGroup(final SequenceI firsthit, + long alisqfrom, long alisqto, JSONArray others, boolean justDelete) + { + if (others != null) + { + final SequenceGroup repgroup = new SequenceGroup(); + repgroup.setSeqrep(firsthit); + repgroup.addOrRemove(firsthit, false); + repgroup.setStartRes(0); + repgroup.setEndRes(resultAl.getWidth() - 1); + for (Object otherseq : others.toArray(new JSONObject[0])) { - System.err.println("Warn - no match for json hit " + sname + "/" - + alisqfrom + "-" + alisqto); + String repseq = (String) ((JSONObject) otherseq).get("dn"); + SequenceI[] other = resultAl.findSequenceMatch(repseq); + if (other != null && other.length > 0) + { + if (justDelete) + { + for (SequenceI oth : other) + { + resultAl.deleteSequence(oth); + } + ; + } + else + { + int ofound = 0; + for (SequenceI oth : other) + { + if (oth.getStart() == alisqfrom && oth.getEnd() == alisqto) + { + ofound++; + repgroup.addSequence(oth, false); + } + } + if (ofound == 0) + { + System.err.println("Warn - no match for redundant hit " + + repseq + "/" + alisqfrom + "-" + alisqto); + } + if (ofound > 1) + { + System.err + .println("Warn - multiple matches for redundant hit " + + repseq + "/" + alisqfrom + "-" + alisqto); + } + } + } } - if (found > 1) + if (repgroup.getSequences().size() > 1) { - System.err.println("Warn - multiple matches for json hit " + sname - + "/" + alisqfrom + "-" + alisqto); + // queue a hide operation + final HmmerJSONProcessor me = this; + viewOps.add(new Runnable() + { + @Override + public void run() + { + me.viewAl.hideRepSequences(firsthit, repgroup); + } + }); } } } + Map groups = new HashMap(); + + private void addArchGroup(SequenceI seqToAdd, String groupNam) + { + SequenceGroup sg = groups.get(groupNam); + if (sg == null) + { + sg = new SequenceGroup(); + sg.setName(groupNam); + sg.addSequence(seqToAdd, false); + sg.setStartRes(0); + sg.setEndRes(resultAl.getWidth() - 1); + groups.put(groupNam, sg); + resultAl.addGroup(sg); + } + else + { + sg.addSequence(seqToAdd, false); + } + } + private AlignmentAnnotation parsePosteriorProb(String ppline) { Annotation[] ae = new Annotation[ppline.length()];