X-Git-Url: http://source.jalview.org/gitweb/?a=blobdiff_plain;f=unused%2FMapList.java;fp=unused%2FMapList.java;h=a5aa8fd23549c7b0a00032207c4b8f1deedbdca6;hb=4f30214e8098748469c6a4269ac2ed6c5750e4b0;hp=0000000000000000000000000000000000000000;hpb=9dabc02511e3a334a5749a504f57f69d6c9017bd;p=jalview.git diff --git a/unused/MapList.java b/unused/MapList.java new file mode 100644 index 0000000..a5aa8fd --- /dev/null +++ b/unused/MapList.java @@ -0,0 +1,1286 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.util; + +import java.util.ArrayList; +import java.util.Arrays; +import java.util.List; + +/** + * A simple way of bijectively mapping a non-contiguous linear range to another + * non-contiguous linear range. + * + * Use at your own risk! + * + * TODO: efficient implementation of private posMap method + * + * TODO: test/ensure that sense of from and to ratio start position is conserved + * (codon start position recovery) + */ +public class MapList +{ + + public static final int POS = 0; + public static final int POS_FROM = 1; // for countPos + public static final int DIR_FROM = 2; // for countPos + public static final int POS_TO = 3; // for countToPos + public static final int DIR_TO = 4; // for countToPos + private static final int FROM_REMAINDER = 5; + public static final int LEN = 6; +/* + * Subregions (base 1) described as { [start1, end1], [start2, end2], ...} + */ + private List fromShifts; + + /* + * Same format as fromShifts, for the 'mapped to' sequence + */ + private List toShifts; + + /* + * number of steps in fromShifts to one toRatio unit + */ + private int fromRatio; + + /* + * number of steps in toShifts to one fromRatio + */ + private int toRatio; + + /* + * lowest and highest value in the from Map + */ + private int fromLowest; + + private int fromHighest; + + /* + * lowest and highest value in the to Map + */ + private int toLowest; + + private int toHighest; + + /** + * Constructor + */ + public MapList() + { + fromShifts = new ArrayList<>(); + toShifts = new ArrayList<>(); + } + + /** + * Two MapList objects are equal if they are the same object, or they both + * have populated shift ranges and all values are the same. + */ + @Override + public boolean equals(Object o) + { + if (o == null || !(o instanceof MapList)) + { + return false; + } + + MapList obj = (MapList) o; + if (obj == this) + { + return true; + } + if (obj.fromRatio != fromRatio || obj.toRatio != toRatio + || obj.fromShifts == null || obj.toShifts == null) + { + return false; + } + return Arrays.deepEquals(fromShifts.toArray(), obj.fromShifts.toArray()) + && Arrays.deepEquals(toShifts.toArray(), + obj.toShifts.toArray()); + } + + /** + * Returns a hashcode made from the fromRatio, toRatio, and from/to ranges + */ + @Override + public int hashCode() + { + int hashCode = 31 * fromRatio; + hashCode = 31 * hashCode + toRatio; + for (int[] shift : fromShifts) + { + hashCode = 31 * hashCode + shift[0]; + hashCode = 31 * hashCode + shift[1]; + } + for (int[] shift : toShifts) + { + hashCode = 31 * hashCode + shift[0]; + hashCode = 31 * hashCode + shift[1]; + } + + return hashCode; + } + + /** + * Returns the 'from' ranges as {[start1, end1], [start2, end2], ...} + * + * @return + */ + public List getFromRanges() + { + return fromShifts; + } + + /** + * Returns the 'to' ranges as {[start1, end1], [start2, end2], ...} + * + * @return + */ + public List getToRanges() + { + return toShifts; + } + + /** + * Flattens a list of [start, end] into a single [start1, end1, start2, + * end2,...] array. + * + * @param shifts + * @return + */ + protected static int[] getRanges(List shifts) + { + int[] rnges = new int[2 * shifts.size()]; + int i = 0; + for (int[] r : shifts) + { + rnges[i++] = r[0]; + rnges[i++] = r[1]; + } + return rnges; + } + + /** + * + * @return length of mapped phrase in from + */ + public int getFromRatio() + { + return fromRatio; + } + + /** + * + * @return length of mapped phrase in to + */ + public int getToRatio() + { + return toRatio; + } + + public int getFromLowest() + { + return fromLowest; + } + + public int getFromHighest() + { + return fromHighest; + } + + public int getToLowest() + { + return toLowest; + } + + public int getToHighest() + { + return toHighest; + } + + /** + * Constructor given from and to ranges as [start1, end1, start2, end2,...]. + * If any end is equal to the next start, the ranges will be merged. There is + * no validation check that the ranges do not overlap each other. + * + * @param from + * contiguous regions as [start1, end1, start2, end2, ...] + * @param to + * same format as 'from' + * @param fromRatio + * phrase length in 'from' (e.g. 3 for dna) + * @param toRatio + * phrase length in 'to' (e.g. 1 for protein) + */ + public MapList(int from[], int to[], int fromRatio, int toRatio) + { + this(); + this.fromRatio = fromRatio; + this.toRatio = toRatio; + fromLowest = Integer.MAX_VALUE; + fromHighest = Integer.MIN_VALUE; + int added = 0; + + for (int i = 0; i < from.length; i += 2) + { + /* + * note lowest and highest values - bearing in mind the + * direction may be reversed + */ + fromLowest = Math.min(fromLowest, Math.min(from[i], from[i + 1])); + fromHighest = Math.max(fromHighest, Math.max(from[i], from[i + 1])); + if (added > 0 && from[i] == fromShifts.get(added - 1)[1]) + { + /* + * this range starts where the last ended - just extend it + */ + fromShifts.get(added - 1)[1] = from[i + 1]; + } + else + { + fromShifts.add(new int[] { from[i], from[i + 1] }); + added++; + } + } + + toLowest = Integer.MAX_VALUE; + toHighest = Integer.MIN_VALUE; + added = 0; + for (int i = 0; i < to.length; i += 2) + { + toLowest = Math.min(toLowest, Math.min(to[i], to[i + 1])); + toHighest = Math.max(toHighest, Math.max(to[i], to[i + 1])); + if (added > 0 && to[i] == toShifts.get(added - 1)[1]) + { + toShifts.get(added - 1)[1] = to[i + 1]; + } + else + { + toShifts.add(new int[] { to[i], to[i + 1] }); + added++; + } + } + } + + /** + * Copy constructor. Creates an identical mapping. + * + * @param map + */ + public MapList(MapList map) + { + this(); + // TODO not used - remove? + this.fromLowest = map.fromLowest; + this.fromHighest = map.fromHighest; + this.toLowest = map.toLowest; + this.toHighest = map.toHighest; + + this.fromRatio = map.fromRatio; + this.toRatio = map.toRatio; + if (map.fromShifts != null) + { + for (int[] r : map.fromShifts) + { + fromShifts.add(new int[] { r[0], r[1] }); + } + } + if (map.toShifts != null) + { + for (int[] r : map.toShifts) + { + toShifts.add(new int[] { r[0], r[1] }); + } + } + } + + /** + * Constructor given ranges as lists of [start, end] positions. There is no + * validation check that the ranges do not overlap each other. + * + * @param fromRange + * @param toRange + * @param fromRatio + * @param toRatio + */ + public MapList(List fromRange, List toRange, int fromRatio, + int toRatio) + { + this(); + fromRange = coalesceRanges(fromRange); + toRange = coalesceRanges(toRange); + this.fromShifts = fromRange; + this.toShifts = toRange; + this.fromRatio = fromRatio; + this.toRatio = toRatio; + + fromLowest = Integer.MAX_VALUE; + fromHighest = Integer.MIN_VALUE; + for (int[] range : fromRange) + { + if (range.length != 2) + { + // throw new IllegalArgumentException(range); + System.err.println( + "Invalid format for fromRange " + Arrays.toString(range) + + " may cause errors"); + } + fromLowest = Math.min(fromLowest, Math.min(range[0], range[1])); + fromHighest = Math.max(fromHighest, Math.max(range[0], range[1])); + } + + toLowest = Integer.MAX_VALUE; + toHighest = Integer.MIN_VALUE; + for (int[] range : toRange) + { + if (range.length != 2) + { + // throw new IllegalArgumentException(range); + System.err.println("Invalid format for toRange " + + Arrays.toString(range) + + " may cause errors"); + } + toLowest = Math.min(toLowest, Math.min(range[0], range[1])); + toHighest = Math.max(toHighest, Math.max(range[0], range[1])); + } + } + + /** + * Consolidates a list of ranges so that any contiguous ranges are merged. + * This assumes the ranges are already in start order (does not sort them). + * + * @param ranges + * @return the same list (if unchanged), else a new merged list, leaving the + * input list unchanged + */ + public static List coalesceRanges(final List ranges) + { + if (ranges == null || ranges.size() < 2) + { + return ranges; + } + + boolean changed = false; + List merged = new ArrayList<>(); + int[] lastRange = ranges.get(0); + int lastDirection = lastRange[1] >= lastRange[0] ? 1 : -1; + lastRange = new int[] { lastRange[0], lastRange[1] }; + merged.add(lastRange); + boolean first = true; + + for (final int[] range : ranges) + { + if (first) + { + first = false; + continue; + } + if (range[0] == lastRange[0] && range[1] == lastRange[1]) + { + // drop duplicate range + changed = true; + continue; + } + + /* + * drop this range if it lies within the last range + */ + if ((lastDirection == 1 && range[0] >= lastRange[0] + && range[0] <= lastRange[1] && range[1] >= lastRange[0] + && range[1] <= lastRange[1]) + || (lastDirection == -1 && range[0] <= lastRange[0] + && range[0] >= lastRange[1] + && range[1] <= lastRange[0] + && range[1] >= lastRange[1])) + { + changed = true; + continue; + } + + int direction = range[1] >= range[0] ? 1 : -1; + + /* + * if next range is in the same direction as last and contiguous, + * just update the end position of the last range + */ + boolean sameDirection = range[1] == range[0] + || direction == lastDirection; + boolean extending = range[0] == lastRange[1] + lastDirection; + boolean overlapping = (lastDirection == 1 && range[0] >= lastRange[0] + && range[0] <= lastRange[1]) + || (lastDirection == -1 && range[0] <= lastRange[0] + && range[0] >= lastRange[1]); + if (sameDirection && (overlapping || extending)) + { + lastRange[1] = range[1]; + changed = true; + } + else + { + lastRange = new int[] { range[0], range[1] }; + merged.add(lastRange); + // careful: merging [5, 5] after [7, 6] should keep negative direction + lastDirection = (range[1] == range[0]) ? lastDirection : direction; + } + } + + return changed ? merged : ranges; + } + +// /** +// * get all mapped positions from 'from' to 'to' +// * +// * @return int[][] { int[] { fromStart, fromFinish, toStart, toFinish }, int +// * [fromFinish-fromStart+2] { toStart..toFinish mappings}} +// */ +// protected int[][] makeFromMap() +// { +// // TODO not used - remove?? +// return posMap(fromShifts, fromRatio, toShifts, toRatio); +// } +// +// /** +// * get all mapped positions from 'to' to 'from' +// * +// * @return int[to position]=position mapped in from +// */ +// protected int[][] makeToMap() +// { +// // TODO not used - remove?? +// return posMap(toShifts, toRatio, fromShifts, fromRatio); +// } + +// /** +// * construct an int map for intervals in intVals +// * +// * @param shiftTo +// * @return int[] { from, to pos in range }, int[range.to-range.from+1] +// * returning mapped position +// */ +// private int[][] posMap(List shiftTo, int ratio, +// List shiftFrom, int toRatio) +// { +// // TODO not used - remove?? +// +// int[] reg = new int[LEN]; +// +// int iv = 0, ivSize = shiftTo.size(); +// if (iv >= ivSize) +// { +// return null; +// } +// int[] intv = shiftTo.get(iv++); +// int from = intv[0], to = intv[1]; +// if (from > to) +// { +// from = intv[1]; +// to = intv[0]; +// } +// while (iv < ivSize) +// { +// intv = shiftTo.get(iv++); +// if (intv[0] < from) +// { +// from = intv[0]; +// } +// if (intv[1] < from) +// { +// from = intv[1]; +// } +// if (intv[0] > to) +// { +// to = intv[0]; +// } +// if (intv[1] > to) +// { +// to = intv[1]; +// } +// } +// int tF = 0, tT = 0; +// int mp[][] = new int[to - from + 2][]; +// for (int i = 0; i < mp.length; i++) +// { +// reg[POS] = i + from; +// int[] m = shift(reg, shiftTo, ratio, shiftFrom, toRatio); +// if (m != null) +// { +// if (i == 0) +// { +// tF = tT = m[0]; +// } +// else +// { +// if (m[0] < tF) +// { +// tF = m[0]; +// } +// if (m[0] > tT) +// { +// tT = m[0]; +// } +// } +// } +// mp[i] = m; +// } +// int[][] map = new int[][] { new int[] { from, to, tF, tT }, +// new int[to - from + 2] }; +// +// map[0][2] = tF; +// map[0][3] = tT; +// +// for (int i = 0; i < mp.length; i++) +// { +// if (mp[i] != null) +// { +// map[1][i] = mp[i][0] - tF; +// } +// else +// { +// map[1][i] = -1; // indicates an out of range mapping +// } +// } +// return map; +// } + + /** + * addShift + * + * @param pos + * start position for shift (in original reference frame) + * @param shift + * length of shift + * + * public void addShift(int pos, int shift) { int sidx = 0; int[] + * rshift=null; while (sidx shiftTo, int fromRatio, + List shiftFrom, int toRatio) + { + // TODO: javadoc; tests + reg = countPos(shiftTo, reg); + if (reg == null) + { + return null; + } + reg[FROM_REMAINDER] = (reg[POS_FROM] - 1) % fromRatio; + reg[POS] = 1 + (((reg[POS_FROM] - 1) / fromRatio) * toRatio); // toCount + reg = countToPos(shiftFrom, reg); + if (reg == null) + { + return null; // throw new Error("Bad Mapping!"); + } + // reg is now filled + // System.out.println(fromCount[0]+" "+fromCount[1]+" "+toCount); +// ret3[0] = toPos[0]; +// ret3[1] = fromRemainder; +// ret3[2] = toPos[1]; + return reg; + } + + /** + * count how many positions pos is along the series of intervals. + * + * @param shiftTo + * @param pos + * @return number of positions or null if pos is not within intervals + */ + protected static int[] countPos(List shiftTo, int[] reg) + { + int pos = reg[POS]; + int count = 0, iv = 0, ivSize = shiftTo.size(); + while (iv < ivSize) + { + int[] intv = shiftTo.get(iv++); + if (intv[0] <= intv[1]) + { + if (pos >= intv[0] && pos <= intv[1]) + { + reg[POS_FROM] = count + pos - intv[0] + 1; + reg[DIR_FROM] = 1; + return reg; + } + else + { + count += intv[1] - intv[0] + 1; + } + } + else + { + if (pos >= intv[1] && pos <= intv[0]) + { + reg[POS_FROM] = count - pos + intv[0] + 1; + reg[DIR_FROM] = -1; + return reg; + } + else + { + count += intv[0] - intv[1] + 1; + } + } + } + return null; + } + + /** + * count out pos positions into a series of intervals and return the position + * + * @param shiftFrom + * @param pos + * @return position pos in interval set + */ + protected static int[] countToPos(List shiftFrom, int[] reg) + { + int count = 0, diff = 0, iv = 0, ivSize = shiftFrom.size(); + int pos = reg[POS]; + while (iv < ivSize) + { + int[] intv = shiftFrom.get(iv++); + diff = intv[1] - intv[0]; + if (diff >= 0) + { + if (pos <= count + 1 + diff) + { + reg[POS_TO] = intv[0] + pos - count - 1; + reg[DIR_TO] = 1; + return reg; + } + else + { + count += 1 + diff; + } + } + else + { + if (pos <= count + 1 - diff) + { + reg[POS_TO] = intv[0] - (pos - count - 1); + reg[DIR_TO] = -1; + return reg; + } + else + { + count += 1 - diff; + } + } + } + return null;// (diff<0) ? (intv[1]-1) : (intv[0]+1); + } + + /** + * find series of intervals mapping from start-end in the From map. + * + * @param start + * position mapped 'to' + * @param end + * position mapped 'to' + * @return series of [start, end] ranges in sequence mapped 'from' + */ + public int[] locateInFrom(int start, int end) + { + int[] reg = new int[LEN]; + // inefficient implementation + reg[POS] = start; + reg = shiftTo(reg); + if (reg == null) + return null; + // needs to be inclusive of end of symbol position + start = reg[POS_TO]; + reg[POS] = end; + reg = shiftTo(reg); + if (reg == null) + return null; + end = reg[POS_TO]; + return getIntervals(fromShifts, start, end, fromRatio); + } + + /** + * find series of intervals mapping from start-end in the to map. + * + * @param start + * position mapped 'from' + * @param end + * position mapped 'from' + * @return series of [start, end] ranges in sequence mapped 'to' + */ + public int[] locateInTo(int start, int end) + { + int[] reg = new int[LEN]; + reg[POS] = start; + reg = shiftFrom(reg); + if (reg == null) + return null; + start = reg[POS_FROM]; + reg[POS] = end; + reg = shiftFrom(reg); + if (reg == null) + return null; + end = reg[POS_FROM]; + return getIntervals(toShifts, start, end, toRatio); + } + + /** + * like shift - except returns the intervals in the given vector of shifts + * which were spanned in traversing fromStart to fromEnd + * + * @param shiftFrom + * @param fromStart + * @param fromEnd + * @param fromRatio2 + * @return series of from,to intervals from from first position of starting + * region to final position of ending region inclusive + */ + protected static int[] getIntervals(List shiftFrom, + int startpos, int endpos, int fromRatio2) + { +// if (fromStart == null || fromEnd == null) +// { +// return null; +// } +// int startpos, endpos; +// startpos = fromStart[0]; // first position in fromStart +// endpos = fromEnd[0]; // last position in fromEnd + int endindx = (fromRatio2 - 1); // additional positions to get to last + // position from endpos + int intv = 0, intvSize = shiftFrom.size(); + int iv[], i = 0, fs = -1, fe_s = -1, fe = -1; // containing intervals + // search intervals to locate ones containing startpos and count endindx + // positions on from endpos + while (intv < intvSize && (fs == -1 || fe == -1)) + { + iv = shiftFrom.get(intv++); + if (fe_s > -1) + { + endpos = iv[0]; // start counting from beginning of interval + endindx--; // inclusive of endpos + } + if (iv[0] <= iv[1]) + { + if (fs == -1 && startpos >= iv[0] && startpos <= iv[1]) + { + fs = i; + } + if (endpos >= iv[0] && endpos <= iv[1]) + { + if (fe_s == -1) + { + fe_s = i; + } + if (fe_s != -1) + { + if (endpos + endindx <= iv[1]) + { + fe = i; + endpos = endpos + endindx; // end of end token is within this + // interval + } + else + { + endindx -= iv[1] - endpos; // skip all this interval too + } + } + } + } + else + { + if (fs == -1 && startpos <= iv[0] && startpos >= iv[1]) + { + fs = i; + } + if (endpos <= iv[0] && endpos >= iv[1]) + { + if (fe_s == -1) + { + fe_s = i; + } + if (fe_s != -1) + { + if (endpos - endindx >= iv[1]) + { + fe = i; + endpos = endpos - endindx; // end of end token is within this + // interval + } + else + { + endindx -= endpos - iv[1]; // skip all this interval too + } + } + } + } + i++; + } + if (fs == fe && fe == -1) + { + return null; + } + List ranges = new ArrayList<>(); + if (fs <= fe) + { + intv = fs; + i = fs; + // truncate initial interval + iv = shiftFrom.get(intv++); + iv = new int[] { iv[0], iv[1] };// clone + if (i == fs) + { + iv[0] = startpos; + } + while (i != fe) + { + ranges.add(iv); // add initial range + iv = shiftFrom.get(intv++); // get next interval + iv = new int[] { iv[0], iv[1] };// clone + i++; + } + if (i == fe) + { + iv[1] = endpos; + } + ranges.add(iv); // add only - or final range + } + else + { + // walk from end of interval. + i = shiftFrom.size() - 1; + while (i > fs) + { + i--; + } + iv = shiftFrom.get(i); + iv = new int[] { iv[1], iv[0] };// reverse and clone + // truncate initial interval + if (i == fs) + { + iv[0] = startpos; + } + while (--i != fe) + { // fix apparent logic bug when fe==-1 + ranges.add(iv); // add (truncated) reversed interval + iv = shiftFrom.get(i); + iv = new int[] { iv[1], iv[0] }; // reverse and clone + } + if (i == fe) + { + // interval is already reversed + iv[1] = endpos; + } + ranges.add(iv); // add only - or final range + } + // create array of start end intervals. + int[] range = null; + if (ranges != null && ranges.size() > 0) + { + range = new int[ranges.size() * 2]; + intv = 0; + intvSize = ranges.size(); + i = 0; + while (intv < intvSize) + { + iv = ranges.get(intv); + range[i++] = iv[0]; + range[i++] = iv[1]; + ranges.set(intv++, null); // remove + } + } + return range; + } + +// /** +// * get the 'initial' position of mpos in To +// * +// * @param mpos +// * position in from +// * @return position of first word in to reference frame +// */ +// public int getToPosition(int[]) +// { +// // TODO not used - remove?? +// int[] mp = shiftTo(mpos); +// if (mp != null) +// { +// return mp[0]; +// } +// return mpos; +// } +// +// /** +// * get range of positions in To frame for the mpos word in From +// * +// * @param mpos +// * position in From +// * @return null or int[] first position in To for mpos, last position in to +// * for Mpos +// */ +// public int[] getToWord(int mpos) +// { +// // never called +// int[] mp = shiftTo(mpos); +// if (mp != null) +// { +// return new int[] { mp[0], mp[0] + mp[2] * (getFromRatio() - 1) }; +// } +// return null; +// } + + /** + * get From position in the associated reference frame for position pos in the + * associated sequence. + * + * @param pos + * @return + */ + public int getMappedPosition(int[] reg) + { + // TODO not used - remove?? + int pos = reg[POS]; + reg = shiftFrom(reg); + if (reg != null) + { + return reg[POS_TO]; + } + return pos; + } + +// public int[] getMappedWord(int[] reg) +// { +// // TODO not used - remove?? +// reg = shiftFrom(reg); +// if (reg != null) +// { +// return new int[] { mp[0], mp[0] + mp[2] * (getToRatio() - 1) }; +// } +// return null; +// } + + /** + * + * @return a MapList whose From range is this maplist's To Range, and vice + * versa + */ + public MapList getInverse() + { + return new MapList(getToRanges(), getFromRanges(), getToRatio(), + getFromRatio()); + } + + /** + * test for containment rather than equivalence to another mapping + * + * @param map + * to be tested for containment + * @return true if local or mapped range map contains or is contained by this + * mapping + */ + public boolean containsEither(boolean local, MapList map) + { + // TODO not used - remove? + if (local) + { + return ((getFromLowest() >= map.getFromLowest() + && getFromHighest() <= map.getFromHighest()) + || (getFromLowest() <= map.getFromLowest() + && getFromHighest() >= map.getFromHighest())); + } + else + { + return ((getToLowest() >= map.getToLowest() + && getToHighest() <= map.getToHighest()) + || (getToLowest() <= map.getToLowest() + && getToHighest() >= map.getToHighest())); + } + } + + /** + * String representation - for debugging, not guaranteed not to change + */ + @Override + public String toString() + { + StringBuilder sb = new StringBuilder(64); + sb.append("["); + for (int[] shift : fromShifts) + { + sb.append(" ").append(Arrays.toString(shift)); + } + sb.append(" ] "); + sb.append(fromRatio).append(":").append(toRatio); + sb.append(" to ["); + for (int[] shift : toShifts) + { + sb.append(" ").append(Arrays.toString(shift)); + } + sb.append(" ]"); + return sb.toString(); + } + + /** + * Extend this map list by adding the given map's ranges. There is no + * validation check that the ranges do not overlap existing ranges (or each + * other), but contiguous ranges are merged. + * + * @param map + */ + public void addMapList(MapList map) + { + if (this.equals(map)) + { + return; + } + this.fromLowest = Math.min(fromLowest, map.fromLowest); + this.toLowest = Math.min(toLowest, map.toLowest); + this.fromHighest = Math.max(fromHighest, map.fromHighest); + this.toHighest = Math.max(toHighest, map.toHighest); + + for (int[] range : map.getFromRanges()) + { + addRange(range, fromShifts); + } + for (int[] range : map.getToRanges()) + { + addRange(range, toShifts); + } + } + + /** + * Adds the given range to a list of ranges. If the new range just extends + * existing ranges, the current endpoint is updated instead. + * + * @param range + * @param addTo + */ + static void addRange(int[] range, List addTo) + { + /* + * list is empty - add to it! + */ + if (addTo.size() == 0) + { + addTo.add(range); + return; + } + + int[] last = addTo.get(addTo.size() - 1); + boolean lastForward = last[1] >= last[0]; + boolean newForward = range[1] >= range[0]; + + /* + * contiguous range in the same direction - just update endpoint + */ + if (lastForward == newForward && last[1] == range[0]) + { + last[1] = range[1]; + return; + } + + /* + * next range starts at +1 in forward sense - update endpoint + */ + if (lastForward && newForward && range[0] == last[1] + 1) + { + last[1] = range[1]; + return; + } + + /* + * next range starts at -1 in reverse sense - update endpoint + */ + if (!lastForward && !newForward && range[0] == last[1] - 1) + { + last[1] = range[1]; + return; + } + + /* + * just add the new range + */ + addTo.add(range); + } + + /** + * Returns true if mapping is from forward strand, false if from reverse + * strand. Result is just based on the first 'from' range that is not a single + * position. Default is true unless proven to be false. Behaviour is not well + * defined if the mapping has a mixture of forward and reverse ranges. + * + * @return + */ + public boolean isFromForwardStrand() + { + return isForwardStrand(getFromRanges()); + } + + /** + * Returns true if mapping is to forward strand, false if to reverse strand. + * Result is just based on the first 'to' range that is not a single position. + * Default is true unless proven to be false. Behaviour is not well defined if + * the mapping has a mixture of forward and reverse ranges. + * + * @return + */ + public boolean isToForwardStrand() + { + return isForwardStrand(getToRanges()); + } + + /** + * A helper method that returns true unless at least one range has start > end. + * Behaviour is undefined for a mixture of forward and reverse ranges. + * + * @param ranges + * @return + */ + private boolean isForwardStrand(List ranges) + { + boolean forwardStrand = true; + for (int[] range : ranges) + { + if (range[1] > range[0]) + { + break; // forward strand confirmed + } + else if (range[1] < range[0]) + { + forwardStrand = false; + break; // reverse strand confirmed + } + } + return forwardStrand; + } + + /** + * + * @return true if from, or to is a three to 1 mapping + */ + public boolean isTripletMap() + { + return (toRatio == 3 && fromRatio == 1) + || (fromRatio == 3 && toRatio == 1); + } + + /** + * Returns a map which is the composite of this one and the input map. That + * is, the output map has the fromRanges of this map, and its toRanges are the + * toRanges of this map as transformed by the input map. + *

+ * Returns null if the mappings cannot be traversed (not all toRanges of this + * map correspond to fromRanges of the input), or if this.toRatio does not + * match map.fromRatio. + * + *

+   * Example 1:
+   *    this:   from [1-100] to [501-600]
+   *    input:  from [10-40] to [60-90]
+   *    output: from [10-40] to [560-590]
+   * Example 2 ('reverse strand exons'):
+   *    this:   from [1-100] to [2000-1951], [1000-951] // transcript to loci
+   *    input:  from [1-50]  to [41-90] // CDS to transcript
+   *    output: from [10-40] to [1960-1951], [1000-971] // CDS to gene loci
+   * 
+ * + * @param map + * @return + */ + public MapList traverse(MapList map) + { + if (map == null) + { + return null; + } + + /* + * compound the ratios by this rule: + * A:B with M:N gives A*M:B*N + * reduced by greatest common divisor + * so 1:3 with 3:3 is 3:9 or 1:3 + * 1:3 with 3:1 is 3:3 or 1:1 + * 1:3 with 1:3 is 1:9 + * 2:5 with 3:7 is 6:35 + */ + int outFromRatio = getFromRatio() * map.getFromRatio(); + int outToRatio = getToRatio() * map.getToRatio(); + int gcd = MathUtils.gcd(outFromRatio, outToRatio); + outFromRatio /= gcd; + outToRatio /= gcd; + + List toRanges = new ArrayList<>(); + List ranges = getToRanges(); + + for (int ir = 0, nr = ranges.size(); ir < nr; ir++) + { + int[] range = ranges.get(ir); + int[] transferred = map.locateInTo(range[0], range[1]); + if (transferred == null || transferred.length % 2 != 0) + { + return null; + } + + /* + * convert [start1, end1, start2, end2, ...] + * to [[start1, end1], [start2, end2], ...] + */ + for (int i = 0, n = transferred.length; i < n; i += 2) + { + toRanges.add(new int[] { transferred[i], transferred[i + 1] }); + } + } + + return new MapList(getFromRanges(), toRanges, outFromRatio, outToRatio); + } + +}