From: gmungoc Date: Thu, 26 Apr 2018 15:09:09 +0000 (+0100) Subject: JAL-2962 start on help updates X-Git-Tag: Release_2_11_1_0~78^2~9^2~15 X-Git-Url: http://source.jalview.org/gitweb/?a=commitdiff_plain;h=904d2d844982ac214ff989516b10d3e4ea01a842;p=jalview.git JAL-2962 start on help updates --- diff --git a/help/html/calculations/pca.html b/help/html/calculations/pca.html index 0104078..5b76d10 100755 --- a/help/html/calculations/pca.html +++ b/help/html/calculations/pca.html @@ -60,15 +60,15 @@ Calculating PCAs for aligned sequences
Jalview can perform PCA analysis on both proteins and nucleotide sequence alignments. In both cases, components are generated by an - eigenvector decomposition of the matrix formed from the sum of - substitution matrix scores at each aligned position between each - pair of sequences - computed with one of the available score - matrices, such as BLOSUM62, + eigenvector decomposition of the matrix formed from pairwise similarity + scores between each pair of sequences. The similarity score model is + selected on the calculations dialog, and + may use one of the available score matrices, such as + BLOSUM62, PAM250, or the simple single - nucleotide substitution matrix. The options available for - calculation are given in the Change - Parameters menu. + nucleotide substitution matrix, or by sequence percentage identity, + or sequence feature similarity.