From cee65885b13fc0f2d56c1f5df439be1df363e3b1 Mon Sep 17 00:00:00 2001
From: jprocter
Date: Sat, 8 Mar 2008 02:51:06 +0000
Subject: [PATCH] correction to Jnet service documentation
---
help/html/webServices/jnet.html | 183 +++++++++++++++++++--------------------
1 file changed, 91 insertions(+), 92 deletions(-)
diff --git a/help/html/webServices/jnet.html b/help/html/webServices/jnet.html
index 7a6015a..a8727db 100755
--- a/help/html/webServices/jnet.html
+++ b/help/html/webServices/jnet.html
@@ -1,92 +1,91 @@
-
-
-JNet Secondary Structure Prediction
-
-
-JNet Secondary Structure Prediction
-
-Secondary structure prediction methods attempts to infer the likely secondary
-structure for a protein based on its amino acid composition and
-similarity to sequences with known secondary structure. The JNet
-method uses several different neural networks and decides on the
-most likely prediction via a jury network.
-
-- Cuff J. A and Barton G.J (1999) Application of enhanced multiple
-sequence alignment profiles to improve protein secondary
-structure prediction Proteins 40 502-511
-
-The function available from the Web Service→Secondary
-Structure Prediction→JNet Secondary Structure
-Prediction menu does two different kinds of prediction,
-dependent upon the currently selected region:
-
-- If nothing is selected, and the displayed sequences appear to
-be aligned, then a JNet prediction will be run for the first
-sequence in the alignment, using the current
-alignment. Otherwise the first sequence will be submitted for prediction.
-
-- If
-just one sequence (or a region on one sequence) has been selected,
-it will be submitted to the automatic JNet prediction server
-for homolog detection and prediction.
-
-- If a set of sequences are selected, and they appear to be aligned,
-then the alignment will be used for a Jnet prediction on the
-first sequence selected in the set (that is, the one
-nearest the top of the alignment window).
-
-
-Note: JNet secondary structure prediction is a
- 'non-column-separable' service - predictions are based on the
- sequence profile of contiguous stretches of amino-acid sequence. This
- means that all columns of the alignment, or selection will be submitted
- for prediction, not just the visible ones (see hiding columns).
-
The result of a JNet prediction for a sequence is a new annotated
- alignment window:
-
-
-The sequence for which the prediction was made is the first one in the
-alignment. If a sequence based prediction was made then the remaining
-sequences in the alignment are the aligned parts of homologs which
-were used to construct a sequence profile for the prediction. If the
-prediction was made using a multiple alignment, then the original
-multiple alignment will be returned, annotated with the prediction.
-
-The annotation bars below the alignment are as follows:
-
-- Lupas_21, Lupas_14, Lupas_28
-Coiled-coil predictions for the sequence. These are binary
-predictions for each location.
-- JNETSOL25,JNETSOL5,JNETSOL0
-Solvent accessibility predictions - binary predictions of 25%, 5%
-or 0% solvent accessibility.
-- JNetPRED
-The consensus prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNetCONF
-The confidence estimate for the prediction. High values mean high
-confidence. prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNetALIGN
-Alignment based prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNetHMM
-HMM profile based prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- jpred
-Jpred prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNETPSSM
-PSSM based prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNETFREQ
-Amino Acid frequency based prediction - helices are marked as red tubes, and
-sheets as dark green arrows.
-- JNETJURY
-A '*' in this annotation indicates that the JNETJURY was invoked
-to rationalise significantly different primary predictions.
-
-
-
-
+
+
+JNet Secondary Structure Prediction
+
+
+JNet Secondary Structure Prediction
+Secondary structure prediction methods attempts to infer the
+likely secondary structure for a protein based on its amino acid
+composition and similarity to sequences with known secondary structure.
+The JNet method uses several different neural networks and decides on
+the most likely prediction via a jury network.
+
+ - Cuff J. A and Barton G.J (1999) Application of enhanced
+ multiple sequence alignment profiles to improve protein secondary
+ structure prediction Proteins 40 502-511
+
+
+The function available from the
+Web Service→Secondary Structure
+Prediction→JNet Secondary Structure Prediction
+menu does two different kinds of prediction, dependent upon the
+currently selected region:
+
+
+ - If nothing is selected, and the displayed sequences appear to
+ be aligned, then a JNet prediction will be run for the first sequence
+ in the alignment, using the current alignment. Otherwise the first
+ sequence will be submitted for prediction.
+ - If just one sequence (or a region on one sequence) has been
+ selected, it will be submitted to the automatic JNet prediction server
+ for homolog detection and prediction.
+ - If a set of sequences are selected, and they appear to be
+ aligned, then the alignment will be used for a Jnet prediction on the first
+ sequence selected in the set (that is, the one nearest the top of the
+ alignment window).
+
+Note: JNet secondary structure prediction is a
+'non-column-separable' service - predictions are based on the sequence
+profile of contiguous stretches of amino-acid sequence. A prediction
+will only be made on the visible parts of a sequence (see hiding columns) as if it were
+a contiguous polypeptide chain. Prediction accuracy at the hidden column
+boundaries may therefore be less than indicated by JNet's own
+reliability score (see below).
+The result of a JNet prediction for a sequence is a new annotated
+alignment window:
+
+The sequence for which the prediction was made is the first one
+in the alignment. If a sequence based prediction was made then the
+remaining sequences in the alignment are the aligned parts of homologs
+which were used to construct a sequence profile for the prediction. If
+the prediction was made using a multiple alignment, then the original
+multiple alignment will be returned, annotated with the prediction.
+The annotation bars below the alignment are as follows:
+
+
+ - Lupas_21, Lupas_14, Lupas_28
+ Coiled-coil predictions for the sequence. These are binary
+ predictions for each location.
+ - JNETSOL25,JNETSOL5,JNETSOL0
+ Solvent accessibility predictions - binary predictions of 25%,
+ 5% or 0% solvent accessibility.
+ - JNetPRED
+ The consensus prediction - helices are marked as red tubes,
+ and sheets as dark green arrows.
+ - JNetCONF
+ The confidence estimate for the prediction. High values mean
+ high confidence. prediction - helices are marked as red tubes, and
+ sheets as dark green arrows.
+ - JNetALIGN
+ Alignment based prediction - helices are marked as red tubes,
+ and sheets as dark green arrows.
+ - JNetHMM
+ HMM profile based prediction - helices are marked as red
+ tubes, and sheets as dark green arrows.
+ - jpred
+ Jpred prediction - helices are marked as red tubes, and sheets
+ as dark green arrows.
+ - JNETPSSM
+ PSSM based prediction - helices are marked as red tubes, and
+ sheets as dark green arrows.
+ - JNETFREQ
+ Amino Acid frequency based prediction - helices are marked as
+ red tubes, and sheets as dark green arrows.
+ - JNETJURY
+ A '*' in this annotation indicates that the JNETJURY was
+ invoked to rationalise significantly different primary predictions.
+
+
+
+
--
1.7.10.2