From e1f1933f8038dd46960bf5c564e37de8211732ae Mon Sep 17 00:00:00 2001
From: Jim Procter
Trees
- are constructed from a distance matrix formed from the normalised
- hamming distance between the sequence features observed in each column of
- the alignment.
Distances are computed based on
- the currently displayed feature types. Sequences with similar
- distributions of features of the same type will be grouped
- together in trees computed with this metric.
+
Distances are computed based on the currently displayed feature
+ types. Sequences with similar distributions of features of the
+ same type will be grouped together in trees computed with this
+ metric. This measure was introduced in Jalview 2.9
Similarities are summed over all columns and divided by
+ the number of columns.
Since the total number of
+ feature types is constant over all columns of the alignment,
+ we do not scale the matrix, so tree distances can be
+ interpreted as the average number of features that differ over
+ all sites in the aligned region.
+
Tree Construction Methods
-- 1.7.10.2