X-Git-Url: http://source.jalview.org/gitweb/?p=jalview.git;a=blobdiff_plain;f=src%2Fjalview%2Futil%2FMapList.java;h=c5654fbee62fd697f85c53ebb55e44302eb28b29;hp=dc5bee876134fee1ea42afc4a767a51c90fe893f;hb=c17981672620e0b780a2338bd0c74e55cf9ddec2;hpb=34abca821ae5c3f9220bfc246c3055e3ba9f39c3 diff --git a/src/jalview/util/MapList.java b/src/jalview/util/MapList.java index dc5bee8..c5654fb 100644 --- a/src/jalview/util/MapList.java +++ b/src/jalview/util/MapList.java @@ -24,6 +24,8 @@ import java.util.ArrayList; import java.util.Arrays; import java.util.List; +import jalview.bin.Cache; + /** * A simple way of bijectively mapping a non-contiguous linear range to another * non-contiguous linear range. @@ -77,8 +79,8 @@ public class MapList */ public MapList() { - fromShifts = new ArrayList(); - toShifts = new ArrayList(); + fromShifts = new ArrayList<>(); + toShifts = new ArrayList<>(); } /** @@ -103,10 +105,9 @@ public class MapList { return false; } - return Arrays - .deepEquals(fromShifts.toArray(), obj.fromShifts.toArray()) - && Arrays - .deepEquals(toShifts.toArray(), obj.toShifts.toArray()); + return Arrays.deepEquals(fromShifts.toArray(), obj.fromShifts.toArray()) + && Arrays.deepEquals(toShifts.toArray(), + obj.toShifts.toArray()); } /** @@ -117,8 +118,17 @@ public class MapList { int hashCode = 31 * fromRatio; hashCode = 31 * hashCode + toRatio; - hashCode = 31 * hashCode + fromShifts.toArray().hashCode(); - hashCode = 31 * hashCode + toShifts.toArray().hashCode(); + for (int[] shift : fromShifts) + { + hashCode = 31 * hashCode + shift[0]; + hashCode = 31 * hashCode + shift[1]; + } + for (int[] shift : toShifts) + { + hashCode = 31 * hashCode + shift[0]; + hashCode = 31 * hashCode + shift[1]; + } + return hashCode; } @@ -201,8 +211,7 @@ public class MapList /** * Constructor given from and to ranges as [start1, end1, start2, end2,...]. - * If any end is equal to the next start, the ranges will be merged. There is - * no validation check that the ranges do not overlap each other. + * There is no validation check that the ranges do not overlap each other. * * @param from * contiguous regions as [start1, end1, start2, end2, ...] @@ -220,7 +229,6 @@ public class MapList this.toRatio = toRatio; fromLowest = Integer.MAX_VALUE; fromHighest = Integer.MIN_VALUE; - int added = 0; for (int i = 0; i < from.length; i += 2) { @@ -230,36 +238,16 @@ public class MapList */ fromLowest = Math.min(fromLowest, Math.min(from[i], from[i + 1])); fromHighest = Math.max(fromHighest, Math.max(from[i], from[i + 1])); - if (added > 0 && from[i] == fromShifts.get(added - 1)[1]) - { - /* - * this range starts where the last ended - just extend it - */ - fromShifts.get(added - 1)[1] = from[i + 1]; - } - else - { - fromShifts.add(new int[] { from[i], from[i + 1] }); - added++; - } + fromShifts.add(new int[] { from[i], from[i + 1] }); } toLowest = Integer.MAX_VALUE; toHighest = Integer.MIN_VALUE; - added = 0; for (int i = 0; i < to.length; i += 2) { toLowest = Math.min(toLowest, Math.min(to[i], to[i + 1])); toHighest = Math.max(toHighest, Math.max(to[i], to[i + 1])); - if (added > 0 && to[i] == toShifts.get(added - 1)[1]) - { - toShifts.get(added - 1)[1] = to[i + 1]; - } - else - { - toShifts.add(new int[] { to[i], to[i + 1] }); - added++; - } + toShifts.add(new int[] { to[i], to[i + 1] }); } } @@ -319,6 +307,12 @@ public class MapList fromHighest = Integer.MIN_VALUE; for (int[] range : fromRange) { + if (range.length != 2) + { + // throw new IllegalArgumentException(range); + Cache.log.error("Invalid format for fromRange " + + Arrays.toString(range) + " may cause errors"); + } fromLowest = Math.min(fromLowest, Math.min(range[0], range[1])); fromHighest = Math.max(fromHighest, Math.max(range[0], range[1])); } @@ -327,6 +321,12 @@ public class MapList toHighest = Integer.MIN_VALUE; for (int[] range : toRange) { + if (range.length != 2) + { + // throw new IllegalArgumentException(range); + Cache.log.error("Invalid format for toRange " + + Arrays.toString(range) + " may cause errors"); + } toLowest = Math.min(toLowest, Math.min(range[0], range[1])); toHighest = Math.max(toHighest, Math.max(range[0], range[1])); } @@ -335,6 +335,16 @@ public class MapList /** * Consolidates a list of ranges so that any contiguous ranges are merged. * This assumes the ranges are already in start order (does not sort them). + *

+ * The main use case for this method is when mapping cDNA sequence to its + * protein product, based on CDS feature ranges which derive from spliced + * exons, but are contiguous on the cDNA sequence. For example + * 

+   *   CDS 1-20  // from exon1
+   *   CDS 21-35 // from exon2
+   *   CDS 36-71 // from exon3
+   * 'coalesce' to range 1-71
+   *
* * @param ranges * @return the same list (if unchanged), else a new merged list, leaving the @@ -342,18 +352,19 @@ public class MapList */ public static List coalesceRanges(final List ranges) { - if (ranges == null || ranges.size() < 2) { + if (ranges == null || ranges.size() < 2) + { return ranges; } boolean changed = false; - List merged = new ArrayList(); + List merged = new ArrayList<>(); int[] lastRange = ranges.get(0); int lastDirection = lastRange[1] >= lastRange[0] ? 1 : -1; lastRange = new int[] { lastRange[0], lastRange[1] }; merged.add(lastRange); boolean first = true; - + for (final int[] range : ranges) { if (first) @@ -361,25 +372,6 @@ public class MapList first = false; continue; } - if (range[0] == lastRange[0] && range[1] == lastRange[1]) - { - // drop duplicate range - changed = true; - continue; - } - - /* - * drop this range if it lies within the last range - */ - if ((lastDirection == 1 && range[0] >= lastRange[0] - && range[0] <= lastRange[1] && range[1] >= lastRange[0] && range[1] <= lastRange[1]) - || (lastDirection == -1 && range[0] <= lastRange[0] - && range[0] >= lastRange[1] - && range[1] <= lastRange[0] && range[1] >= lastRange[1])) - { - changed = true; - continue; - } int direction = range[1] >= range[0] ? 1 : -1; @@ -387,11 +379,10 @@ public class MapList * if next range is in the same direction as last and contiguous, * just update the end position of the last range */ - boolean sameDirection = range[1] == range[0] || direction == lastDirection; + boolean sameDirection = range[1] == range[0] + || direction == lastDirection; boolean extending = range[0] == lastRange[1] + lastDirection; - boolean overlapping = (lastDirection == 1 && range[0] >= lastRange[0] && range[0] <= lastRange[1]) - || (lastDirection == -1 && range[0] <= lastRange[0] && range[0] >= lastRange[1]); - if (sameDirection && (overlapping || extending)) + if (sameDirection && extending) { lastRange[1] = range[1]; changed = true; @@ -404,7 +395,7 @@ public class MapList lastDirection = (range[1] == range[0]) ? lastDirection : direction; } } - + return changed ? merged : ranges; } @@ -798,7 +789,7 @@ public class MapList { return null; } - List ranges = new ArrayList(); + List ranges = new ArrayList<>(); if (fs <= fe) { intv = fs; @@ -959,15 +950,17 @@ public class MapList // TODO not used - remove? if (local) { - return ((getFromLowest() >= map.getFromLowest() && getFromHighest() <= map - .getFromHighest()) || (getFromLowest() <= map.getFromLowest() && getFromHighest() >= map - .getFromHighest())); + return ((getFromLowest() >= map.getFromLowest() + && getFromHighest() <= map.getFromHighest()) + || (getFromLowest() <= map.getFromLowest() + && getFromHighest() >= map.getFromHighest())); } else { - return ((getToLowest() >= map.getToLowest() && getToHighest() <= map - .getToHighest()) || (getToLowest() <= map.getToLowest() && getToHighest() >= map - .getToHighest())); + return ((getToLowest() >= map.getToLowest() + && getToHighest() <= map.getToHighest()) + || (getToLowest() <= map.getToLowest() + && getToHighest() >= map.getToHighest())); } } @@ -1087,8 +1080,33 @@ public class MapList */ public boolean isFromForwardStrand() { + return isForwardStrand(getFromRanges()); + } + + /** + * Returns true if mapping is to forward strand, false if to reverse strand. + * Result is just based on the first 'to' range that is not a single position. + * Default is true unless proven to be false. Behaviour is not well defined if + * the mapping has a mixture of forward and reverse ranges. + * + * @return + */ + public boolean isToForwardStrand() + { + return isForwardStrand(getToRanges()); + } + + /** + * A helper method that returns true unless at least one range has start > + * end. Behaviour is undefined for a mixture of forward and reverse ranges. + * + * @param ranges + * @return + */ + private boolean isForwardStrand(List ranges) + { boolean forwardStrand = true; - for (int[] range : getFromRanges()) + for (int[] range : ranges) { if (range[1] > range[0]) { @@ -1113,4 +1131,114 @@ public class MapList || (fromRatio == 3 && toRatio == 1); } + /** + * Returns a map which is the composite of this one and the input map. That + * is, the output map has the fromRanges of this map, and its toRanges are the + * toRanges of this map as transformed by the input map. + *

+ * Returns null if the mappings cannot be traversed (not all toRanges of this + * map correspond to fromRanges of the input), or if this.toRatio does not + * match map.fromRatio. + * + * 

+   * Example 1:
+   *    this:   from [1-100] to [501-600]
+   *    input:  from [10-40] to [60-90]
+   *    output: from [10-40] to [560-590]
+   * Example 2 ('reverse strand exons'):
+   *    this:   from [1-100] to [2000-1951], [1000-951] // transcript to loci
+   *    input:  from [1-50]  to [41-90] // CDS to transcript
+   *    output: from [10-40] to [1960-1951], [1000-971] // CDS to gene loci
+   *
+ * + * @param map + * @return + */ + public MapList traverse(MapList map) + { + if (map == null) + { + return null; + } + + /* + * compound the ratios by this rule: + * A:B with M:N gives A*M:B*N + * reduced by greatest common divisor + * so 1:3 with 3:3 is 3:9 or 1:3 + * 1:3 with 3:1 is 3:3 or 1:1 + * 1:3 with 1:3 is 1:9 + * 2:5 with 3:7 is 6:35 + */ + int outFromRatio = getFromRatio() * map.getFromRatio(); + int outToRatio = getToRatio() * map.getToRatio(); + int gcd = MathUtils.gcd(outFromRatio, outToRatio); + outFromRatio /= gcd; + outToRatio /= gcd; + + List toRanges = new ArrayList<>(); + for (int[] range : getToRanges()) + { + int[] transferred = map.locateInTo(range[0], range[1]); + if (transferred == null || transferred.length % 2 != 0) + { + return null; + } + + /* + * convert [start1, end1, start2, end2, ...] + * to [[start1, end1], [start2, end2], ...] + */ + for (int i = 0; i < transferred.length;) + { + toRanges.add(new int[] { transferred[i], transferred[i + 1] }); + i += 2; + } + } + + return new MapList(getFromRanges(), toRanges, outFromRatio, outToRatio); + } + + /** + * Answers true if the mapping is from one contiguous range to another, else + * false + * + * @return + */ + public boolean isContiguous() + { + return fromShifts.size() == 1 && toShifts.size() == 1; + } + + /** + * Returns the [start, end...] positions in the range mapped from, that are + * mapped to by part or all of the given begin-end of the range mapped to. + * Returns null if begin-end does not overlap any position mapped to. + * + * @param begin + * @param end + * @return + */ + public int[] getOverlapsInFrom(final int begin, final int end) + { + int[] overlaps = MappingUtils.findOverlap(toShifts, begin, end); + + return overlaps == null ? null : locateInFrom(overlaps[0], overlaps[1]); + } + + /** + * Returns the [start, end...] positions in the range mapped to, that are + * mapped to by part or all of the given begin-end of the range mapped from. + * Returns null if begin-end does not overlap any position mapped from. + * + * @param begin + * @param end + * @return + */ + public int[] getOverlapsInTo(final int begin, final int end) + { + int[] overlaps = MappingUtils.findOverlap(fromShifts, begin, end); + + return overlaps == null ? null : locateInTo(overlaps[0], overlaps[1]); + } }