From: Jim Procter Date: Fri, 10 Jun 2022 11:13:11 +0000 (+0100) Subject: Merge branch 'features/r2_11_2_alphafold/JAL-2349_JAL-3855' into develop X-Git-Tag: Release_2_11_3_0~23^2~60 X-Git-Url: http://source.jalview.org/gitweb/?p=jalview.git;a=commitdiff_plain;h=fbfbbe26bee37143d5279fe4d254a5a89c96b021;hp=a7634a9f5f5f691a7bff7bb05ca21a340aa2f834 Merge branch 'features/r2_11_2_alphafold/JAL-2349_JAL-3855' into develop --- diff --git a/examples/testdata/raptorxeg/0README_total b/examples/testdata/raptorxeg/0README_total new file mode 100644 index 0000000..dab87a7 --- /dev/null +++ b/examples/testdata/raptorxeg/0README_total @@ -0,0 +1,23 @@ +----------------------------------------------------------------- +Explanation of files in seqid.all_in_one.zip, +where seqid is a number assigned by CoinFold to the query sequence +----------------------------------------------------------------- + +0README_total : This README file. + +seqid.fasta : The user input sequence in FASTA format. + +seqid.a2m : Generated Multiple Sequence Alignment (MSA) in A2M format. + +seqid.contactmap.txt : The predicted contact result file. + +seqid.png : The predicted contact image file. + +models/ : The folder contains the predicted five 3D models. + 0README : The README file for the explanation of predicted models. + seqid_model_X.pdb : The predicted models in PDB format, where X ranges from 1 to 5. + seqid.model_summary : The summary file contains the energy score from CNS_solver for each predicted 3D model. + + +In this package, except the image file, all the other files are saved in plain text format. + diff --git a/examples/testdata/raptorxeg/195600.a2m b/examples/testdata/raptorxeg/195600.a2m new file mode 100644 index 0000000..9d2f0fe --- /dev/null +++ b/examples/testdata/raptorxeg/195600.a2m @@ -0,0 +1,6124 @@ +MAPKKVLLALTSYNDVFYSDGAKTGVFVVEALHPFNTFRKEGFEVDFVSETGKFGWDEHSLAKDFLNGQDETDFKNKDSDFNKTLAKIKTPKEVNADDYQIFFASAGHGTLFDYPKAKDLQDIASEIYANGGVVAAVCHGPAIFDGLTDKKTGRPLIEGKSITGFTDVGETILGVDSILKAKNLATVEDVAKKYGAKYLAPVGPWDDYSITDGRLVTGVNPASAHSTAVRSIDALKNHHHHHH +-------------------------------------------------------------------------------------------------ITKFFLSSAGHGTLFDYPKAKDLQDIASEIYANGGVVAAVCHGPAIFDGLTDKKTGRPLIEGKSITGFTDVGETILGVDSILKAKNLATVEDVAKKYGAKYLAPVGPWDDYSITDGRLVTGVNPASAHSTAVRSID---------- +-----------------------------------------------------------------------------------------------------------MVLYLTIPKLKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNGAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAIN---------- +-------------------------------------------------------------------------------------------------KYGLFFASAGHASLIDYPTASTLQNIAEQVWASGGIVASVCHGPAIFTNLLDRTTGKPLIQGKKITGFTTEADNAMGIMAELRGFGSEMVEELAERLGAKYERSSGIWDDFHVVDGRLVTGQNPVSSTSTAKAAIE---------- +MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIQNNKTINRRQSYNRFPTRG-------------------------------------------------------------------------- +PLPKHAVITVTSANADLFN-------------------------GKETTKTGNYTPYWLSLQADFFNGSDKEMYDDLQSEFRQKLDNMPTPSELDGNKYGIFFASAGHAALIDYPNATGLQKIAEVIWANGGVVSAVCHGPAIFANIKDKATGKPVIAGRTITGFTNEG-------------------------------------------------------------------------- +MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKKSARYCIQDICQWGCDRCHLSWTAPFRWINRYQNNKTINRRQSYNRFPTRG-------------------------------------------------------------------------- +--MVKVLLALTSEDPVFYPDGKKTGVFTIEALHPFEEFKKKGYEVQFASETGSFGYDDYGISPDFLNGENRKIFEDPNSDYNQALKKTKKASDLDPNDYDIFFASAGHGTLFDYPKSKSLQLIASTVYDKGGIVAAVCHGPIIFDNMKNLKTGEPLIKGKKITGFTDIG-------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------------ITKFFFASAGHGTLFDYPKAKDLQDIASEIYANGGVVAAVCHGPAIFDGLTDKKTGRPLIEGKSITGFTDVGETILGVDSILKAKNLATVEDVAKKI------------------------------------------------- +--------------VLFMKTVQRPEHISLKSCIPFKSLQRQGIVFRLS-VRMVMLADDHSISDSALSDSDKNAFKDKNNDFWKAIKNAKNASDINFSDYSIFFAAGGHGTLFDFPSATNLHKGAAKIYSMGGVIAAVCHGPVILPCIKDS-TGFSIVKGKTVTAFNEIAEQQMNLMPTFEKYHFKTLNKLFQEAGSNFVDPQEPFDDFVKTDGKLVTGANPASAASTAKAALN---------- +--------------GPFYLDGMKTGAFFSETLVPYKVFKQAGYEVQIVSETGQCKFDDKSLTNIALGNLEKQVLDDKNDDFWECLKNAKSAKEINPDEYPLLFIAGGHGAMFDLPTAKDMQNLAARIYENRGILAALCHGPVLLVHVQNTKKGKSVVYDKNVTAFTHAGEVMMGLSTPLKNHNIGFLNEILEQAGARYINPSTPVSDFVQVDGRIVTGVNPQSAESTAKAAVE---------- +--------------VPFYPDGKKTGVHFSELLEPYKVFRENGFAVDFTSPNGSCQFDESSVDESSLPENEKKILHDKQDEFWKDLKRMIPAANVDPADYCLMFVAGGHAAMFDLPTAVDLHAVAAQIYKNGGVIAAVCHGPVMLPFVQDLKGEVSIVKGKHVTAFSKQGEQAMGVMNQMKQHHFRTLNEVFNSAGANFIDPPDPMGEFVQSDCRVVTGVNPASAIATAKTAVQ---------- +--------------GPFYPDGKNTGVHFSELLIPYNVFKKAGFNVQFVSENGSYKFDDHSIEESKLGDFERKVFNDKNDDFWTNLNNMKKASDIVGKDYQLLFVAGGHAAMFDLPKATNLQAVAREVFTNGGVLSAVCHGPVLLANVKNPQEGKTVVYHKHVTAFNKAGEEKMGVMDELKKRGMKSLNEIFAEAGATFIDPPNPNVNFTQIDGKIVTGVNPQSAKSTAEAAVS---------- +--------------GPFYLDGMKTGAYFSETLVPFKVFRKAGYDVQMVSESGQCRFDDHSLTETNLGELEKQVLDDKNEEFWTYLKNTKAAKDVDPNEYPLLFVAGGHGAMFDLPTAKGVQNLAAKVYDNKGILAAVCHGPVLLAHVKNSKVGKSVVYGKNVTAFTHAGEVMMGLSTSMRNHNIGFLNEILEQAEAKYINPPTPVSDFVQVDGRIVTGVNPQSAKSTAEAAIN---------- +--------------GPFYPDGMNTGVHFAELLIPYQVFREAGYEVQLTSETGKCKFDDHSIKKSALGEVERDAFDNKDNEFWYALKDIKPADKINYKEFCIMFIAGGHAAMFDLPHATNLQTLAQQIYASNGVLAAVCHGPVMLPFVDDTKEGRSVVYGKKVTAFNSTGELVMGVSSALRERNMQDLNSLFREAGAEFVDPPTPMSDFTQVDGRIVTGVNPMSAKSTAEAAIK---------- +--PRRALIAVTSANALLMEGKHVTGLFVAEALHPYNVLTAAGFEVDLASETGKYTADWLSVQPDFLNGKDLETWKDTNSEFRKKLDNMPKASELDPSKYGVFFASAGHASLIDYPTAKGLQNIAAQVWANGGIVSSVCHGPAIFANLIDPATKEHLIKGKKITGFTTEAERDMKLDETIKSWNVELVEELAARVGATYERGAGVWDDFHVVDGRLITGQNPQSSNSTAKAIVDA--------- +--SKHILMIVSNSATS--NIGKPVGICAVELIHPYAVLKASGCQVTIASSQGPIELDAQSEPRDPSGFLSSARY-ITQAAFTDQLSNTPAISNLNTQDYDAIFVCGGQGTLYTFPKDKALTDLFVSFYQDEKPSATLCRGACLLLNAT-LDNGEPLIQGKMITGFSKKEEQWMSKNF-GPMMVPFVVEEEAKKRGAKFV-ASSAFTPFVIQDSNLITGQQSNSAFLTASLVLKAL-------- +--MTNALFVTTSCDALA-P-DHPTGLWL---AVPYMAA--AGIDITVASPRGAVPLDPKTEPND------------EWAPALESLRHSVTLES----AFDAVFIPGGHGPMMDLAHDATLHELLARQDAAGRLIAAVCHGPAALVNAKRAD-GAPFLKGRRATGFTNTEERLAGLKD----VVPFLLEDAMKG--ADFHSALVPMLSHVEH-GNLLTGQNPHSSAALAKKLVDAL-------- +--NEKILMVVTNGHTMEN---ELAGIWL---SEAYLEF--AGYEVEVASPKGKSPVDPNSLTDD-----------AEDKEAGKLLEETKRLSDVSS-EFAGIFVPGGHGTMFDFPEDAH-QRLLTEFAEDDKLIAAVCHGPAALVGGKR-A-GEPIVKGKKVTSFTDAEEADTK--LD---YMPFLLETKLREL-AEFVAK-DNWTDHIEV-GKLLTGQNPQSTISLAKQFIRVL-------- +-------------MLIIVS--DRHGFWL---LEPYQLL--AGYQITIASPKGQGKASGFRLS----------WF-KQ-SKLKLQLKRSIPLAEVNP-SYAAVYFAGGAGPMFDLPDNAL-QQITRDIYEAGGIVAADCHGPAALINIML-S-GKRLISGKKITAKANSEEGSWA---R---NYPFLLEDKIKEL-GRYLA-SGKNQQHVVV-GRLITGQNPASAIPMAERLIEQL-------- +--RPQVLLV-------A--SSSTQGWYLPEFAHPYKVLSP-HVDLVIASPNGATVLDPVSYEL--FK---CMEF-AATKS--KLWLETKKLSDYTGKEFAAIFYIGGFGPMFDLVDNEVSTSLIREFHESGKIVATLCHGAAALLNAK-LSDGTLLVKGENITGFSNAEEIAVDRQ-KDM---PFHLETYLNNAGG-YKKAEKAWDPLVVVKKKLVTGQNPASAEGTGEALLKMI-------- +--KPKILVVLTSADKVP-KTGKQIGWY-PELAHPFHVLNP-RAELVYATPKGESPLDPVSVEL--FK---CKDF-LENHESV--WKNTLKLSDVAGPEFDAIFYPGGHGPMVDLVHDEHSKNLLRDFHSQDKVISAVCHGPAAFVNATTA-SGDLILKGKQVTGFDDVGEEMFKFT-DDM---DFSLEKKLDEVGM-YIKADDPLAEKVVVDGKIITGQNPASSKGVAEEIAKAL-------- +--LPKVLIVLSSATKTL--KGEDTGVFISELAHPFYAIHQ-HVDITFASPTGSV-IDPGSIAM--FK---SMSF-LKDRAD-K-YQNNVPLSQIN-AEYDAVFLPGGHGPSIDLIKDNDAQRVISRIYQAGKPVAAVCHAGGVLGNVV-DKHSESIYKGRQATAFSNTEEEMVGKV-QSI---SETPEDHIKR-GV-YVKADQPWGECVIVNGVYISGQNPASAKKLGDEFLKAI-------- +--TLHVLFIVTNAAVLGPR--RKTGFFF---AHPFDVL--AGIAIEFASPAGWTPYDAYDEK----------GF-FE-SKAFRRLNRSRKLSEVDA-DYDAILVPGGLGPMVDIQHNAD-QKAVVRAWSTGKLVTAVCHGPCCLLGVDL-G-GAPFVRGKKLTAFSKKEEHDYA---R---DVPYELEDALIAE-AEYSS-TDNWQPKVVV-GRLITGQNPASAGPLAKELLTAL-------- +--MHSVLFVVSAADHWTLNDLHPTGYWA---AEPHRLF--ADWDITIATPKGAPTVDAGSLSAQA-V----AVI-AAYKAISSDLNHPRSIADITV-DYDVVFYPGGHGPMEDLAVDAV-GRIMTEALVSGRVLGVVCHAPAAMLAAVR-E-GSWPFTGYRMTGFTNEEETLGG--LA---KAPWLVQSRLVEL-ANFVAG-AAWVPHTEI-RNLYTGQNPASSGELASKILAAV-------- +--TSTITILLSEAHILTDGSTQPCGFWAEEFITAHRIFTAANIRTIIATPGGAAHVEPDSMHAP----HSGYRL-SGLSENLRAPAALE---TVDPSTVDGIFVPGGYGPVVDLHKNSHVGEFLRALRREGTPIATVCHGTAALLADT-ASGATWPYAALTMTSFSDQEEADVGLLG----TLPFTVEQEIQRRGG-TYTAGHPWQQHIEITDTLITGQNPASTEAVAEQLTQRI-------- +--MTTIAILLASADSLTDGETYSCGYWAEELVGPWRLFTEQGATVLVTTPEGKATAEPASLVPETASLSQDIRL-DEHATELDAPVAAS---QLDLSAVAGIYVPGGYAPLAQLHDHPEVGTLVTAARERSVPIATVCHGAAALLACR-TATSPWPYAGQTITSFSDAEEKTAGMLG----KLTWTLEQALREAGA-HHQSAEPWSENLTEAPGLITGQNPASCIGVAKALLRQV-------- +--NPHVLVVLS---------SAKPGWFL---AHPYH-I--PHCTITIASHLGAAPLDPLSISSGEDA------AEF---MKA--DLNTAKLEDLI-GEFDAIFYVGGYGPMFDIVD-PASAKIIQVLYANKKLLTGVCHGPAAFAHVNKPS-QEPLLKGHKVTGVSNKECELLFP--V---VEPWSVEDELAKA-AGGYSKA-EVLSKGED-RTFVTGQNPSSGLGVGKAVYKEL-------- +-------------------------------AHPYYQVTNAGYEVEFASPLGAAPLDPSSVEAFKGDEESNTKK-VH--TNYDVLTATFPSATQLSKDYKAIFYVGGHGPIFGLYSDPNSLQLIDEFWRESKPVAAVCHGPVVFIKAIDTATGEPLLRGKKATCFSNKEEEIADLVD----EIPFLVESQMKGV-CHFQNTREPWGVEVVTGKTLITGANPASASETGKALIKAI-------- +--KQKILFVLTSRDKL--LNGEPTGWYLPEAAHPYYVLSP-SFDIDFAAPAGNPPVDPCSFESF--K---SVKF-FNDDVVKSKLRNATKLSDVV-DDYHALFYPGGHGPIFDLAVDPENIRLATHFFQSGKLVGAVCHGQAA----TCINEVTPVFKGRNVTCFSNVEEQQTG--KE---AIPFLIEDVVRLQ-GFYEKASEPWAAHVVADGQLFTGQNPASAGPLAQSILKAL-------- +--TPRILVVLTSHDRID-QLDKPTGWC-PELAHTYDVLCT-RAELVFASPKGVAPPDPSSVEM--FA---SVNF-LKNHKDL--WENTTPLKEFLGLEFAAVFYPGGHGAMYDLANDADSLQLIQEFYVTGNTIAAVSHGPIAFYRAKI--HDKPLLDGRRVTGFTNREEKDLELD-HVL---PLLVETSLTEIAD-FDSVPPHWKKLVVVDGQIITGQNTASAKEVGEAIARAI-------- +--RPRVLFILSSHDKMG-HLDKPTGWYLPEFAHPYYKIEP-WADIVVASPKGAAPLDPASVEM--FK---AMKF-LKEK--ESLWKNTEKLSKYIGDEFDGIFYVGGHGPMFDLATDPESHTLIKEFYEKNKVVSAVCHGPAALANAKLT-DGSYLVAGHEVTGFTNTEEDQVQLS-SAM---PFMLETQLIA-GK-FV-KAEPWQPKVAIANNLITGQNPAIEVQQESTDLEFA-------- +-------MIGTSHNSLGET--HQTGVWL---SHAYDEF--SNIKVSFASIDGGYPLDPGSLD-Q--------NF-LLSSQTRSLLSNVMSLSQAAH-DYDAVYLIGGHGVMWDFKGNPE-DAIISNIYDSNGVLGAVCHGSAGLLTATD-E-GNLLIEGKNITGFSDEEEENIK--LT---IVPFSLEQSLVQA-VKYQKTDNNFESFSII-GRIVTGQNPASATAVAINMIDLL-------- +--MKKVLIPVTNHATLGDT--QANGTYA---THVVHVL--QGIGYELASIQGQVPLYGTDAE----------QM-LEDAELQAKIANTLSVSELNI-DYDAIFYPGGFGLLSDLATDEQ-ATLAATHYEAGGVIAAVCHGPAALLPITL-S-GDPLIGDKSVTCFTREEEIDFG--TI---SIPFLLEEAIARK-AQYRK-VQPWQEFVIE-AGLITGQNPASAHAVGVALAQHL-------- +--MSKILILVTNHATLGET--EANGTFA---THALHEI--AGYDYDLVSIKGQAPMYGTDME----------KI-LADETFQNRINNTIPVSQINV-DYAGIFYPGGFGLLTDLAKNEE-AKLTAKHYEDGGVVSAVCHGPAGLLPVKL-S-GESLLSKIKVTGFTREEEVDFG--TI---KIPFLLEESLARA-KNYSK-TQPWGEYVVQ-SRVITGQNPASAGAVGKALVEAL-------- +--MAKVLAVLSSGYTDE-EHNYVTGWWAEEL-------EKEGHTVELASIDGKPIVDPISISADY-----GIYK-KQ--YESGIADKTMPIVNVKASDYDAIMIVGGHGAMFDLAHNKDLHAVINVVYETGGIVSAVCHGPAPLIYTK-TKEGRPLLEGLKVTGYPNDKEP-KEIVD----LLPFSLEDELTNI--NYH-EEKDHDAYVV-SKQILTGRDPQSSELFGRELAQKL-------- +--SKKILVVLTNTAKYPTL--RATGLWL---VHFVEKV--AGYTVDYVSPQGYVPVDPHSLQ--MA----DWQW-YDNKRFMTRLGSTLAPGQVKA-EYSVIYYTGGHGVMYDFAENQP-QELARKIYEKGGIVAAVCHGVVGLLNIKL-S-NCLLLKDRKVTGFSNIEEKLAE--LD---KVPFLTETELGAR-GEYSKHDDPWKPYVVD-DRLITGQNPASTALLAEAVLKKL-------- +-------MVTTSHSKMGDL--KKTGLWL---THPYYSI--ENIIIDIVSITGEIPIDPNSVA-E--------RF-LADDNLKNIIKNSTSLRDVNI-EYDAIIFAGGHGTMWDFPNDSN-QNKILDVYSRNGVVGAICHGVAALINVKD-N-GKNIISDKEVTGFSNNEEKIVG--LT---VMPFSLEDSLVKV-AKYSS-ALEWQSCVKN-AKIITAQNPKSATDFGKQIKQTL-------- +--MKNVLMVTTSHDVMGNS--EKTGLWL---THPYYSI--KNINIDIVSIMGEIPIDPNSVA-Q--------KF-LADDNLKNIMKNSTSLRDVNI-EYDAIIFAGGHGTMWDFPNNAN-HSKVLDIYAKNGVIGAICHGVAALINVKD-N-GQNIIRDKEVTGFSNNEEKIVG--LT---VVPFSLEDSLVEA-AKYSS-ASEWQSYVKS-SKIITAQNPQSATDFAKAIKQSL-------- +--MKKILIILTNTRYYGN--KDKTGLWL---AEFVYKV--HGYQVDYTSVNGEVPLDPRSL-KST-----IDEI-YYSNDFR-ALKHSLKVSDLDP-DYFAIYYTGGHGVLWDFPNQPA-SSITNSIFKQGGFIMSICHGLAGLVTIKD-D-GNYLINNKKITGFTNFEEILSG--KL---KVPFLTENQAKKA-AKFVQ-KRPFASFAVQ-GQFITGQNPMSGFAVADLLIKNS-------- +--MKPILILATNQDHYEGY--IPTGLWL---THFIHIM--KGIPFKIASLKGEIPLDPYSLSEQ--------PY-YDDLRFMSELVNSQSLDKLNP-NYSAIYFAGGHGAMYDFVQDPR-AQWILAMTKMQKPVAAVCHGVAALTNQALEI-DQVFVEGKTVTGYTNAEELHVG--HS---HVPFLLQDRLQRL-ANFGE-AGPFQSHVQL-RRLLTGQNPQSTKELAETLADML-------- +--MKRVLHVVTNVGHYDDP--HATGLWL---THAWHVF--AGFDQTLVSPAGAVPLEPRSLKFPSYD---AKAW-RADPAKMDLLATTKSPEEID-ADFDAVYFTGGHAVMYDFPDSEGLQRITREIYERGGIVSSVCHGYCGLLNTRL-S-GSYLIDGKHMTGFAWQEEVLARVDK----LVPYNAEERAKER-ALYKKAKLPFVSYTVT-GNLVTGQNPGSAKATAQKVVEAL-------- +--MKRILNVVTNVGHYDDP--HATGLWL---THAWHVF--AGFEQTLVSPAGASPLEPRSLKFPTYD---AKAW-RADPAKMELLATTKSPEEID-ADFDAIYFTGGHAVMYDFPGSEGLQRITREIYERGGIVSSVCHGYCGLLDTRL-S-GTYLIDGKHMTGFAWQEEVLARVDK----LVPYNAEERAKER-ALYEKATLPFVSYTLT-GNLVTGQNPGSAKATARKVVEAL-------- +--MKKIMIVNTSYDQFDGF--LPTGLWL---VHFYDVFN-PNYQLDIYNINGETPIDPVSM-NK--------KY-YEDETFMRKLHDSPSIDEADV-QYDVIYFTGGHGVMYDFRGHDT-ARAVNDIYDRGGLVSSVCHGTSALLEIKR-P-DHFLIEGQKLTGFSNREESIAR--RK---QVPYQLETALKEK-ALYQKSIIPLKSFVVE-EQLITGQNPASARDVGEAIKLRL-------- +--AKRILFVSTSHE--D-T--KKTGLHL---AEAHKIL--NGFEIDFANPKGKSRVYETDVN----------EF-IQNQSAFHQFSNPLKLSEIIP-KYSAMYISGGHGAMWDLPAHPQ-DSIIRSIYEQNGIVAAVSHGPAALVNVHL-S-GELLIKGKKLTAFTNKEEKESG--YH---IVPFLLESKLKKE-SIFSS-SGSWQKYIIR-GQLITGQNPASTIALAEEIVKAI-------- +--LIKILIIVTNINMYAN---YPTGLWL---THIYQAA--KGYDVTIASPNGDVPIDPESLK--------SKKY-WDDNSFRELLKNSRSLKEVEN-NFDVVYLAGGHGTMYDFPDDKT-QKIIGDQYESGKMVAAICHGVGGLLNVKL-S-GNYLIKDKKLTGYNWFEEGLAG--RK---EVPFNLEETLKNQ-SDYRKVLIPMTSKVVV-GNLITGQNPFSSKKMAKVVVREL-------- +--TSKILIIVTNSDLFEKV--YRTGLWL---VEFWDIA--AGYKMDIASPSGKTPLDPESL-LITEM-GD--RR-YEDKGFMSRLDNTLKVSDADP-GYDAIYMTGGHGVMFDFPKSAS-AELTAGFYEAGKIVSAACHGPCGLLEVKL-S-GTYLINGKQITGFSWKEEKLAN--RD---AVPFNLEEELQKR-GRYSKAMMPFGSHVVE-GLLITAQNPKSTKNLGQAVIKKL-------- +--EHQILVIMTNHASYPSR--DTTGLWL---THFTDVV--AGYTTVFASPKGAVPLDERSL-GW--------RH-LQSATFRARLQNTLPIADVDP-RFSAIYFTGGHGVMWDFPNNPD-RRVAETIYNQGGIVSAVCHGVAGLLDLKD-D-GRLIIKGRNITGFSDREEWLSG--MK---QVPFFLEDRLVSQ-ARYHKGWLPFTSFALT-GRLVTGQNPQSPRAVAEAVTAAL-------- +--MPKILLVLTSSKMMG-E--KETGFWL---AAPHAIF--AGYEVDIASPEGAPPVDAGSKADA------TRRF-DADAAAQAKLAATTKLSD----AYAAVFFAGGHGTCVDFPNNPSVQGVMEKVYGAGGVISAVCHGPTAFVGAKTAD-GAALVSGKKMTGFTDTEEAQVGLTD----KVPFLLEAKLIE--ADFSKAD-PWTPYAVV-GRVVTGQNPMSSELTAQKVVEVL-------- +--SKKVLFILTSRNQYD-D--TPTGLWL---SEPYNIL--ADIAVDITSIEGAVPLDPNSTQNN-----------DKYAEFVAKIKDVPSIAEVDV-QYDAVYLPGGHGTVFDYAHNQQ-SSILADFKDEDKIISSVCHGPSAFVGAKD-K-GNFLVNGVTLTSFTDEEERAMG--LE---KVPFLTQTELENQ-AKFVT-KENFTEHIEI-SQFITGQNPQSSVAIGKALRDAL-------- +--MSRILFILTNHDRML-N-GEPTGVWL---AVPYQML--AGHDVSVASVAGQVPIDPNSAVDD------------AWQDAIEQLESTPAFDT----RFDAVYMPGGHGTVFDMPYNGKLHALLFSFADTDRIIASVCHAPAVFGGMRRDD-GTPFIAGRHVAGFTDSEERAAGGEE----KVPFLLESRLKA--AQHEGAE-DWHPLAVQ-GKLITGQNPQSSAAVAEKLIAAL-------- +--MANVLMVVSNAIKVK---SYETGYWSEEF-------EDAGHKVTIASPKGDAKVDTFSLTDQW-----GVSK-AF--EELGRWKETKRLSDLSGKDFDAVVFVGGHGPMFDVAYDAHAHRIINEIYDNGGIVAAECHAPAVLAFTV-KPDGTSIIQGKKVTSYPDVYEP-ENVLE----FLPYSVEQELSKV--EYV-SDLDSPQLAI-DDQIITSRDPVSSEAIANELLKAL-------- +--TKKVLFVLTSTSQFP-D--TQTGLWL---SVPYQVL--ADIDVDVVSIEGEVPIDDNSTQNN-----------ETYKQFVDLIQDVPALNLVNT-EYDAIYLPGGHGTVFDFANNPQ-SDILLSFKEDNKFIASVCHGPSAFVGAKD-K-GNSLINNMTLTSFTDEEERQMG--FE---QVPFLTQTALQDL-ANFKA-AEAFSSHVET-GQLITGQNPQSSQAVGEALRDAL-------- +--MTKILMIATNVDQLD-S--HQTGLWL---VEPATEF--AGFEVVAASLKGRIPIDPHSYSNE-----------RVWDGVMEPIHNTPLLSEIDP-EFEVVFLCGGHGAMMDFPNNKT-EHVLRHFLTKKKIIASVGHGAAGLIGVTD-H-GEAIVKGRTMTGFTDAEEKETG--IE---LLPFTIEEKLQAE-AGFEG-DNPDKDHVEV-EHFITGQNPRSSLSTAQAVIKKL-------- +--LKRILLVSTSAHDMN----HPTGLWL---AAPYSVF--AKFDVDIVSIKGRVPIDRVSIPNG-------REF--KH--VASLLQNTKPISTVHF-DYDAVLFGGGHGAIVDFPGNPY-ANLIENMYNNNRIVAAVCHGVSSLVGVKN-K-GSFFVAGKRITGYTNDEEKAVH--LE---RVPFLLESKLKEE-ALFYV-APKFTPHVVV-GHLITGQNPQSSMEIGKAIRRAV-------- +--MARILILSTASDALG-ETGKPTGVWY---ATPYYAF--AGHEVTLVTLGGPVPIDPNSDVAS------VSRF-RDDAAATALLAAPGPLEA----EYDVLYIPGGHVADVYLAESDLVAEVIGKAWDQGKIVASVCHGPAAFSKAVDAE-GTPIVTGRKVSAFTDSEERGVGLAE----AMPFLLETRLRE--ADFDGIA-DWQPHSVV-GRLVTGQNPASSDGAAEKVLALL-------- +--EKRVLFVCTSCDRFK-AVDEKTGLWA---AAPYYEF--QGAKCDVASIKGAIPLDPNSLAEN------VKRF-HQNEHGLKDKEKSIAIK-----TYDAIFLPGGHGVCFDFAENAELIALVEKFWADGKIVAAVCHGPVGLCGPLTPD-GDPIVKGKKVTGFSNSEEAAVGKTD----KVPYLLEDKLKK--GRYESGS-DWTPYAVA-GRLITGQNPQSSLKTAQLVVEAF-------- +--RQTIESYDILISTLK-G--HKTGLWI---AAPYYEF--AGYEVEIASPEGAVPIDAASLGEG------AKKF-MHDAEAIGMLSHSTKLAS----TADAIFICGGHGTCTDFADNGVLKAAIETMYSSDKIVSAVCHGPVSLPQCNKPD-GTPLVKDKVVTGFKDSEELAVQLEK----LVPFMLETKLKE--GKYESAD-DWNSKVCV-GKLVTGQNPQSSEACAAVVIGIL-------- +---MKVLIVLTNISTYGN--NKKTGLWL---TEFIREL-----KIDFASPNGKVPIDPRSI-K-------SLEI-LKSENDN-SISQSLSIKDVIK-KYDLIYFTGGHGVMWDFYNNPV-EELIRFNYENGAYISSVCHGIAALFNVKT-S-GEFLIHKKKITGFTKTEEILSG--KR---KVPFLNEQAAKNN-ADFIK-KRFFKSHVVV-GHIVTGQNPYSVIELAQTINKLL-------- +--AKRILFVLSGHAAMGG---KPAGCYF---VHPYYVM--RGIELDFTTPGPGPSLAQTDFN----------RL-LMDRQAMDRILGAPRPETVDA-RYDAIFYTGGHGGLYDFPDNPA-IAIAENIWSRGGLVSGMCHGPAGLLNLKD-S-GDYLITGRKVTGFSRAEEVTFG--VL---DIPYVLEDTLASR-ARYHC-YGVNQGFVVR-GRIITGQNWYSSQLVAEALADAL-------- +--MTKALIVATNTPKFNNV--RATGLWL---THFNQVM--NEIDVDYMSPEGYIPLDPLCLSAD-------WDH-YLDATFRDHLANSLKPESVNS-DYQVIYFAGGHGAMWDFPENKE-AGIAEQIDQNGGIIAANCVGVTALLAMRK-R-GNRFTSGRQLTSFTNDEEALNG--LT---EVKFLPEDELRKT-AKFVK-GDAFKPNVVV-DHLITGQNPNSATAVGEAVIKDL-------- +--GKKILVVLTSVAKYPNL--RATGLWL---VHFVKKL--DGHTVDYVSPLGYTPIDPHSLS--MA----DWQW-YQDKAFMNRLGTTLRPDQVKA-DYAAIYYAGGHGVIWDFPDNAA-QALARDIYEAGGVVSSVCHGAVGLLNIKL-S-GALLVAGKRVTGFSNTEEKLAQ--LD---HVPFLTETELVRR-AHYEKAPEPWLPFAIA-QRLITGQNPASGGPVADLVLAEL-------- +--ADKILIVSTSYSKLGNT--EKTGLWL---SHPYIIL--AGYEVDIASVKGRIPIDPNSTK-E--------SF-LNTPESANKLSNSLALKDVSG-DYIGVIFSGGHGSVWDFYPNTD-ARIGTQVQKNNGVIAAVCHGVSALLSIKN-L-NNPIIKGKEIAGFSNSEERAIN--LD---TVPFMLQDALEKQ-AKYNS-GENFTAFVKV-GNIITGQNPQSSSLLAKEILKKL-------- +--QEKILIVVSSLDKKT---NLVGGFWF---THPVKVF--AGFDFDIASPKGLAPFDG--F-D---------DF-WTNPQHRNKLGQTIKLSDVDP-KYSAILLVGGHGPMWDFVNNTE-NNIVRTMYENNDVISAVCHGPAGLINVKL-S-GESLIKDRRLTGFTAAEEVSRQ--YD---IVPFELEGALKKG-AKFEE-APIFENNVVV-GRLMTGQNPASATALGEAVVKAL-------- +--QEKILIVVSSLDKKT---NLVGGFWF---THPVKVF--AGVDFDIASPKGLAPFDG--F-D---------EF-WTNPQHRNKLGQTIKLSDIDP-KYSAILLVGGHGPMWDFVNNTE-SNIVRTLYENNGVISAVCHGPAGLINVKL-S-GEDLIKGRRLTGFTAAEEASRQ--YD---IVPFELQGALKKA-ATFEE-APIFANNVVV-GRLITGQNPASATALGEAVVKAL-------- +--KVKVLLVVTNHTKLGDT--KQTGFYL---AHPYYLF--KSYDVVFTSIKGLAEVDEGSIK--------TCQK-FV-KEFLE-SNQGKYLETYAI-ALDAIFYSGGHGTMWDFPNDSI-NKAAEKIYNNGGVIGAVCHGPAGILNLKD-E-GEYLIKGKNVTGFSNKEEEAVE--LT---VVPFSLEDELKKR-ANYSS-ADNFKSHVVT-TRLVTGQNPASSSTCAEAVIDQV-------- +--MVAVLIVSTSANNWG-E--NSTGVWL---ACPYYLF--KGYQVDICSIAGKVPIDAGSLADN--------KFLAESSELLDKTLKLGDLLPDLV-KYSCIYLAGGHGTITDFPDDPA-KQSVESMFAAGKVVAADCHGPVGFVNCKK-P-GEPLVKGLRVTGFSNTEETQVG--HIMKKGGYIILEDKFKEQ-GSFEAA-DPWVSFAVA-KNLVTGQNPQSSAECANKCMELI-------- +--SKKVAIVCTSASEF---QGHPTGAWLEEIATPYYAFKAAGLDVTIVSIAGKVPIDAASTQG--DF---CVKF-TSDADAVKALESSVALAAYDFDACAGVYLAGGHGTCVDFYNAPDAQRCLNKVYADGKPLAADCHGPIALLNCVKP-DGSALVADKAVTGFSDAEEAAVGFT-EKCETHSALLEKTMRAL-GKY-AAAADWNPNVCVDGNLITGQNPASSAKCAEAFVEAL-------- +-------MVCTSCDHVG-D--HDTGVWL---AVPYYIF--NGYDVTFASISGAIPIDQAALMSE-----------ARNVSAMQQLGASVPLATVAP-AYDCVFLAGGQGAMADMPASAQ-HRVLADAAQHGKLIAAVCHGPAGLLGAVD-G-GKPLLAGRTVACFTAQEEDKTG--AA---CMPFQLEQKLREA-ASVRK-AQPGEENALR-GFLITGQNHASAARVANLVVEAL-------- +--YSALPIRLHTRPPHPRRTRQPAGFWA---LGPYAVL--TGHEIAVATTPGVPPADALRTADPEFS------AER---MKPEATENPMRSEDVRVRRLRGRV------PPGRLGS-G---------------------GPARQRRPRQAA---DRVAGLRQTRVAGVPRPGRAA--G---RRRRVRHRLMADL-ANCREAA--FTPHIEV-RTLYTGQNPMSAVPLGRDVIKAL-------- +--MSKILMVISGANSLKMADTHPTGYWA---AASHEVL--EGGDVDLATPGGRPTVDVLSLDERG-G----QRF-RGYDGIADRLAAPLALAD-RA-DYDAIYIPGGHGPMADLVDDDD-GRLLNEA-VQGKIVVALCHGVGALLSAST-P-GGFTFADRELTAFSDEEERQGG--LG---NIPFSVEGRLRER-ARVT-PGAPWSSTVIQ-ATLITGQNPQSSVATARKALAAL-------- +--MIRLLMVVTGVDHLTLVDIRKTGFWA---VVPHELF--AGLVVEIATPGGPAPLDQGSLAPEKNS----KQF-TEYASLE-DLRHPLILERLQI-SYDAIYLPGGHGPMQDLAHSPE-GEILNRM-QDRKLISAVCHGPAGLLPAIR-A-GTWTFQDYRLTAFTNKEENEVG--LA---KMPFLLETQLRDH-ANFQ-SGKSWMPYVIT-RNLVTGQNPASSFGVAEAAIARL-------- +--MPSLLVILTGATKWTQQDQRPTGFWS---VEPHKAF--AGVELTVATPGGPSVVDELSLIAQANN----AEL-RAYDGVKDLLAAPERLEDMDP-AFDGVFIPGGHGPMQDLAVNED-ARILQALLPSSKVVAALCHGQAAFLPAGD-A-GQWLFKGRRLTSFTDEEETQTG--LA---NAPWLIGTRLKAA-ADYVA-GPAWSSHVVV-GNLVTGQNPASAADAANAVLKEL-------- +--MISVLMVLSAATHWTLSDRHPTGVWA---ISPHDVF--AGWKITVATPGGPAVIDPASLGTAGGL----NGF-QDCDRLSPLLRKPLNLYG-DL-DHDLVFYPGGYGSMEDLAQDAV-GAMLSERVATGGPVAFSCHGAAAALGATA-C-DISPFRGRVMTAFSNAEERLTR--IA---RVPWMLEDRLRAA-VEYSRAILPFRPHVVA-RTVYSGQNPQSSGHLARRVVADL-------- +--MTNVLMVVSGAHAWTLADAHPTGFWA---VAADRAF--AGWTVEIATPGGAPQVDPNSLSPQYTG----ADL-RAHDALGDELTRPTALEEVDV-SFDALFLPGGHGPMEDLAVLPL-GETIVAMLDAGRPVAAVCHASAALLSADR-P-GSWAFDGWRLTGFTNAEEEAVG--LA---LAAWLLEDRLRER-AQFAS-GELWAPFLVA-RNLYTGQNPASSGPLAEHVVGVV-------- +--MSKVLIVMSAADTWERTDAYPTGYWA---AAPHQRF--AGFTVDFASPGGLQPLDRHSADPAV------RHV-EHAERALREFGPLLDLAE-DV-DYAAVVLPGGHGPVVDLHRDAD-GRLLTAA-DAGKPIAAVCHGPAALLSAVD-P-GGWLFAGRRMAAFTDEEERLFG--TA---AAPWLLATRLREL-AEHL-AGPAYAAFTVR-GNLFTGQNPASSAPMAEAVIAAL-------- +--MTTVLMAVSAAEHWTLNDHHPTGFWA---VVPYDIF--AGFEVTIATPGAAPTVDPISISVKGGM----KKM-EDKEQMSHVLNNPEDLHK-DA-SYDIIFYPGGHGPMEDLAYDKI-GKILTDRLASGKLLGLLCHSPAALLATID--TGQTPFAGKQITALSNTEEGMVT--DK---KAPWLLEDRLKEA-LKYEKATLPFRPKLVR-GNLFTGQNPQSSEKLAKALVEAV-------- +--TGKILFVMTGADEWTLDDKHKTGFWA---AAPLEVF--AGFAVTVATPRGRPPVDEASLAPDAVG----EQI-RTLETA-PELQNPIALSDADV-EYDAVFVPGGHGPMEDLAVDAD-GALLIAADRARKTIGIVCHGPAILLAAKG-E-GVNAFSGRTVTCFGNAEEQQAG--LA---KAPWLLEDRLIHE-FRVT-LGLPWTVHTES-GNLLTGQNPASSEKLAREVVQRL-------- +--VVDVLMVLTSHGRPP-DGGGGCGLSFDQFLSPYYLFVTAGIDVALASPRGPPPLDPGMDQR--EA---AARF-RSDNAARDLLADTLKLSQVAPEDFAAVLYPGGLGALFDLPADPVSQGLIEAFARAGRPMGFIGHAPAVLAGLRRP-DGAPFVAGRRLTALSDREGWGTGAA-PAP---AWSAEQVLRGL-ADYRC--GPEGRSHLVDGLLVTGQNTASAPGVARELMTLM-------- +--MKNLLIITTNYAPQCNC--QNTGVYL---AVPYLVF--SDINVTVASPNGLSPVDEKSMSCS-----------EEWDDCIKVLRETKKLSEVDY-NFDGVYFPGGHGPMFDLAENKE-AEIVEYFFRSGKLVSAVCHGPAAFVNT-------DIVKGKRVTCFTNEEEGIVK--LQ---LVPFLLETCLINL-AEFVA-EKPWAEHVEV-GNLITGQNQNSALLIAEKIIEFF-------- +--DKPLLMLVTSAAQMGQ---QQTGLWL---ALPWLLF--KNIPVVVASPRGKIPVDPNSVPDD-----------AEWTEAIAALQDTWPLEEIWE-GFAGVFVPGGHGAMFDMPDHPL-AAVMERTWAQGGLLGAVCHGPAALVGLRN-E-GTPLVQNCTLTCFTNEEEREVG--LD---VMPFLLATRLEEL-AKLDLA-DKFVSHAVA-GRLITGQNPQSSQAVADALVDAL-------- +--TKTILFVLTGQAELG-DTGARTGVWL---ATPYRAL--AGHEIMFATPGGPAPLDPASLEEP------GHWL-LGQPAAMAKLEAPLDLAA----RIDAIFLVGGTGTLWDFPACRPLGALATALHAQGKPVAAICHGVVGLMTATAAD-GSPLVAGKAITCFSNAEEAMLEYDK----LVPLLAETALAG--ADYRC-AAPFEPLVVA-GGLITGQNPASAEPLAAALIERL-------- +--NKSVLIVATNHGTINNDK-RPTGLWL---AEPYQIF--AGLQADIVSPKGEVPLDPASLSNG-----------EKFNDVIRLLQNTQSLKDVVY-GYDAIFFAGGHGAMYDFPGNPE-QNIMAYFKDDGRIIGAVCHGPAAFADAKT-K-GSYLVDGVKITGFTNAEEESMN--LM---DMPFALQTKLESH-AGFVAG-SEMESNVVK-RNFVTGQNPASAADAAQAIVNQL-------- +---MSILFVLTSHATFG-D-GRETGLWL---LTPYYSF--AGLPVRLCSPLGNVPVDPASVDALK-----Y-QY-KSDAILAERMNSTAKLSSVS-SDITALVYPGGHGPLWDLRDNPHSVALIESLISSGKPVATICHAGCALLDARKSD-GRPLVEGVQVTAFSDSEEAAVGLEK----AVPYLVETDMKAL-AVYSK-SGDWESHVVV-GSLITGQNPASSLGVAEAVIKRL-------- +--SRRILFVFTSNDRLV-NTTVKTGWYLPEAAHPYYGLKTAGFEINFVSELGRPPLDESSISA--TK---CQRF-LNDAQVQKMLDEAPPLSSIKLPEYDAVFYPGGQGPLIGLPQNTQSQNLIRTMFEDGRVVSAICHAPAVFTEVKLQ-DGKYLVDGRKVTSMSNKEEELWGRV-PYV---PYLVQSRLKER-GIFIEGSTAWGDHVVVGRKLVTGANPASGGSLAREIIKLL-------- +--GSRAVLVLTSHARFG-DSDRPTGFWY---AAPYHAL--AGIEVILASPAGQPPVDPASLAPA------VDRF-RADPDALARLAATVPLAG----AFDSVFLVGGHGTMWDFPANPPLADLLTSVLSRGGTVGAVCHGAAALVDLH-VG-GRPVVNGRQLTAFSDSEEELVAATG----LVPFSLEQRLRS--ANYRAGR-PFAPHVLR-GQLVTGQNPASSTRVAELVIETA-------- +--IFSILIIVTTFSNIS-E--QKTGVWF---AIPYQTF--KNYNITVATIDGDIPIDPNSMP-K-----------TKWKTELNSLKNSVKLSQVDL-KYDAVYIPGGHGAIYDLPKSKE-KEAIEYFANKNKVVASVCHGPASFININL-S-GTPFVKGKTLTSFTNKEEKEANLIAE---ELPFYLETELSKK-AIFIQ-KPNWSDHIEV-ENLITGQNPKSSKSVALAIVDKL-------- +--FNKVLFVVTSHDRMG-N-DRKTGIWI---AAPYYYF--NGKEITIASPKGQAPIDPKSNEPEN-----T-IY-FNDPETIKRLSNTKKISEVN-RDFDTVFYPGGHGPMWDLPDNEDSIHLLESFNRAGKIMTLMCHSPVALINVKDVN-GELLIKGKRVTAFTNGEEATAQLDK----IVPFLLEDKLRSK-ANYQK-GEDWAPFVTR-GRLITGQNPASSVLAAETVMEVF-------- +--TPRILVLTTSHARLG-ATGKPTGVWL---ALPMHWL--QGAVISLASVAGVIPLDPASLPPA------DRRF-LREH--SALLADSPAVAE----SFDALLLPGGHGTVWDLPDGA--APLVEAFYAAGKPIAAVCHGPAGLVGARRPD-GQPIVSGLRVNAFTDHEERLAGLDH----VVPFLLESRLSA--ARFEA-GAAWAPYCTQGSVIITGQNPASSAAVAQALWATL-------- +--KKKILFMVSSASLIGPL--RKTGNLL---AHPYVAF--QGYDIDIYSVKGDAPIDLVELE----------EF-LA-GDGPARFKNTGSIEEVSL-GYDAVFVPGGLAPVVDMPDNPT-QRILSTMWESGKIVSAVCHGPVSLINVKL-S-GSWLVDGKKLTGFSIAEENGYA---K---DVPWELEDRIKEH-AIYTA-VDPWQPYSIT-GRLITGQNPASAQGVAERVIAAL-------- +--KDKVLFILTSHSRLG-DTGRVTGFFF---AVPYYAL--AGYDVDIASIRGAAPVDPASLKDT------VDRF-LNDTKAMRKLSTTKSIDR----AYVGAFIPGGHGAAWDMPGNDVLGSILSTIWARGGVIGAVCHGVNALIGVVDER-GVPLVQGRVVNGFTNSEERAVELDL----AVPFLLESRLRQ--ARFERGD-DFHAFAVH-GRLVTGQNPASSRAVAEEMIAAL-------- +---MKVLMIVTSNDRLG-D-GHKTGLWL---AAPYYVF--AGARVTLASPKGAAPVDPRSETEEA-----T-RF-TADPAAMAALKDTVPLAEVR-EDYDVLFYPGGHGPLWDLVDDARSLAIIEKMHRAGKPVAAVCHGPAVLVRATTPD-GKPLVARRNMTGFSNAEEDAVGLSQ----VVPFLLQDELTRL-AKYER-GPLWEPHVVA-GLLVTGQNPASSERTAKTVLEVL-------- +--MARILFVLTS---RRGGKRAPAGFHWEEFVTPYWAFRDAGHEVVVGSVLGEATGLPGSEVDGPHGRISSVR---ERGQEMELLQGTLPVVAAKAEDFDALFFPGGVGPLWDLHETPEIGALVSAVLARGGIVATVSTGAAALLTAL-DAEGEPIVRRRRIST---APDAELSAAG----PAPYSIEAALVERGARIGRNEYLFRPHALRDGGLVTGQNPASAAPVARLVLSAL-------- +--GKRVLIISTSHEKLG-DTNEKTGLWM---AHPYLIF--HGLEVTVSSTKGEIPVDEASLAAP------VEKF-LLDDSAMAQVLESVPLAD----SYDAVFLPGGHGTCWDFADNELIIKVVNGLARAGKVVAAVCHGANGLVNATDAE-GQPIVKGREVTGFSDAEEYAVAKEK----LIPFMLEERLKE--ANYTKAKENWGVHALLPFPLVTGQNPSSSALTAELIVEAL-------- +--V-RVLMVVTSADKIGKE--HKTGVWF---AVPYLDF--EGYFVTTASLKGKAPIDKKSENLI-----------LKWKAAKQALEDTIPLESIDY-LYDALVLPGGHGPMVDLAHSEL-GEIINYFSENSKIIAAICHGPAGLLPAKK---GTAFVNGRKLTCFTNEEEQCAK--MD---IVPFFLEDALKEQ-AFFMQ-KDEGEINIIE-DNLITGQNYQSAEQFAQTVIRHL-------- +--MKNILMVLTSHSEME-NTDSKTGVWL---TDPYYEF--AGYTITLTSPKGRPPVDPMSELTE------NRRF-QDDEQAKADFSQTTVLDQ----AFDAVFYPGGHGPIWDLARDNNSGILIHDFLDSGKPVAAVCHGPAALISAEQQR---GFLNGKVISAFSNAEETLVGRSH----NVPYLLQTKLED--AKVKTAIVPFLSHVET-GLLVTGQNPLSAGPTAKALIELL-------- +--QKRVLLVMSSLDDMG-ISGKQTGTWF---AAPYYIL--AGHEVVFASPEGEAPIDLLSMKAP------TERF-LKDDVAMFAASRTRKLRN----TFDAVFFPGGYGLLWDLASDQHVIKMIKDFYETGRPVAMVCHAPAILRDVKLSN-GKYLVDGVKLTGFKDAEDAEIELDK----HLLFSLEQDLQL--AKYL-SKANWEPNVVV-GALMTGQSPASAAPLAEVLSKAL-------- +--QKRVLLIMSSVDEMG-ISGKQTGTWF---ATPYYVL--AGYEVVFASPEGNAPIDLLSMKAP------TERF-FNDPVAMFAVQNTRKMRE----TFDALFVPGGYGLIWDLASDSYMIKMIRDFYESGRPVAMVCHAPAILRDIKKSD-GSYLVDGLNLTGFKNDEDSEIELLH----HLLFSLEDEMKR--ANYV-SKANWEANVVE-GALMTGQSPASAPPLAEALKLRL-------- +------MLIAVTSHLGPLG--RPTGAWL---SGFWHEM--AGLDVDYASPRGDPPIDPVSALLP-----------FVRSGERQRLMESMRSVDVDP-RYDAIFFAGGHGALWDLPSDPG-VLATEAIWRAGGVVAAVCHGPAGLLEPKD-A-GRSLLEGRRATCYSNFEETLGG--MA---KVPFLLETSMKER-ARFEKAMLPFMQHVVI-GRLVTGQNPASARGVGRAVAELL-------- +--SSKILFVLTSQADLG-GTGQKTGTWL---ASAWYLL--DGQRLTLASIAGAAPLDPASLEAP------GTRF-LDDPAAVAALAATPRLAE----SFDAVYFVGGAGAAWDFPVDPAVKATIETIDRQGGLVSAVCHGVLALAGATTAD-GRPLVAGRRVTAISNVEEELTTFDK----VVPVLPETRLVE--GVYAKAAEPFGGHVEV-GNIVTGQNPASAPLVAAALLDAL-------- +--TKKVLFILSSHDKLGNS--KPTGWYL---SHPWESL--GGFEIDICSPKGEAPLDPTSDDRV--------AF-MEDHDIARKLKNTLRPEQVNP-DYMAIHFVGGHGCMFDVVTDQK-HEIAMKIYEQHGVISAVCHGPAGITNLKL-K-GSYFVRGKNLCGFSNEEEEIVK--LT---VVPYSLEDRLKER-ANYKS-KPAWSSHVIV-GNLITGQNPQSAKELGEKLTTLI-------- +--MPHVLIVLTSQGLIP-ATRQQTGWQLKQWAYP-YSILEPRVNITIASPQGEAPLDPASASTKPETASDDISS-IA--HHWEAWTHTYRIREVVGGEFDAVFYVGGRGAMFDLVTDAASLALIQNIAAVGKPIAAVSHGPAALLNAT-APSGVPLLSGARLTGFSREEEDEAGMAA----VMPFQLETELERVGGGYVKADRPGMEKVVV-SPLITGQNPASAVGVAREILRVL-------- +----------------MKKD-DKTGLWF---VHFYDVV--AGFPIDIVSINGKVPIDPKSL-LP--------TY-HLDPYFISKLDHSLPLEEING-DYDCVFFAGGHGTLWDFPESKK-QEITAAIYENGGLVTAVCHGPAAFLRTRL-S-GTHLLENVEVTGYSNIEEKLIF--QG---KIPFYLEDELRSV-KSYKKSTIPFTSHVVE-KRIITGQNPQSARAVGEKTLKIL-------- +--MAKILLAVSSHETLGDT--NRTGYSV---AHPYNVF--AGHEVDFVSVRGEPPAVIFDG-E---------GF-LADETVKGKLVATRRAADVDP-PYAAIFYVGGHGAMWDFPDSPD-ARIAMDIHGRGGIVSAVCHGPAALVNLRL-P-GTLLVRGKRVASFTNEEENSLG--LV---VMPFLLEDRLKET-ALHAK-AGMYEAHTES-GRVITGQNPASAAPVARLVVAEL-------- +--MEKLLIAVTNHAALGTG--KKTGLWL---TDFYHEV---DFEVDIISTSRRVPLDPRSL-MA--------AY-YMNDELMDKIKNPFVPEDIDA-DYAAIYFAGGHGTMWDFPDNSE-QEITKTIYENGGMVLAVCHGPSGLQNVKL-S-GRYLLSGHVVTGFSDKEEKLMG--LY---HIPFSLEQALKDR-TLYKQSTFPMAACVLQ-GRLITGQNPASTKGVAQKFLEQW-------- +--AKPVLVVLTSHGTKGST--EKTGYYL---THPVAVL--AGIPVEYASIQGEPPVDG--L-D---------RY-WQNPAFRNAVSHTPRLADVDP-RYAAIFFAGGHGAIWDFPDSAA-QDATRQIYEAGGVVGAVCHGPAAFVNVKL-S-GTYLVAGKRLSAFTDDEERAVQ--LA---VVPFLLASTLAAR-ALLEP-APDWTAKVVV-GRLVTGQNPQSATGVGEALRNLL-------- +--LKKILMVLTSVSEIGED--EPTGYNV---AHPWKVF--SGHFVDFASIKGQPPRDT--V-D---------QF-TQDETTRAGLYNTARVGVVDP-QYDAVYLVGGHGTMWDFPDNEG-QKLVGAIYNKGGVVGAVCHGPAGLLDVEL-H-GLKLLSGKTVAAFTNDEEVAVG--KD---IIPFFLADKLTEQ-ATHIA-ADNFEENVQV-ERLVTGQNPASAAGVAKEMEKLL-------- +--SNAILMVLTGHSELGET--RVTGFHV---AYPWKAF--AGYRVDFATSGTTPTPDS--A-D---------DF-LDDAGVLEQLADPKRPLDIDA-GYKAIFYVGGHGTMWDFPNDTA-SGLARDIYEAGGVVAAICHGPAGLVNVKL-S-GSYLVDGKSLTSFTDSEERAVK--AM---IVPFALESTLVER-AHHTG-MADFTANTVV-DRLVTGQNPASAPMTAAAVVEVL-------- +--KQRIAIVVTSHGKLG-NTGDDTGFHY---TTPYYIF--DGCEVTLGSIQGEPPADPSSLPDD------VRRF-LKDKNAVKALKATVPVSE----DFDAVYLPGGHGCMWDMPDNDALSRLISEVYEKGGVVGAVCHGPAGLLGARLSD-GTPFVKDRLINSFTDEEERKVGKDK----AVPFLLETQLRG--ARFE-GGKPFERHVCR-GRVVTGQNPASAEGVGHGMLMAL-------- +--SRRILFIMTNANTLGDT--LKTGAYL---THAFNEF--AGCEMVMASPFGAIPLDGVKMD----------TW-VNDSNFMSMLQNSIPTYHAQS-DYEAVYIPGGHGASFDLPWDRE-QKLIQEIYENNGVVGAVCHGVAALVNVKL-S-GTYLVSGQEISSFTNDEESIVG--MD---VVPFLLESKLIER-AHFKS-CPAFTECVAR-GRLITGQNPASSIAVANSMLEVM-------- +--SERVLIVVTSHGYIGKD-KGDTGYFL---THPYYQF--AGFDIDIASPKGEPPMDPGSY-K---------RF-VATAEDWSKMQNTLKLSDIAA-DYSAIIFAGGHGTMWDFPDDPD-LRLTRDIYESDGVVAAVCHGPAALVNVTL-S-NRFLVSGREVSTFTNFEERIVR--LY---DMPFLLETQLKER-AQVKKALIPFMEKVSV-GRLVTGQNPNSARAMAEAVVEIL-------- +---MKILILMTNSATLTTGEKHASGFWAEEFVLPYQIFQQEGYEIDVATIGGAPSVDKTSIDPNFMPYVRQARF-IEASSDLKKPLNLDEFTKAQVASYDGIFLSGGHGAMQDMPKSDTMTQLFRWAIELDKPIAAVCHGGSGLLALR-TPEGDWPFEGYRMTCFSHEEELVTPIAG----MLPFILQFEIERLGGIYEKADVIWGSHVVEDRNLVTGQNPYSSDAVAKAFAKKL-------- +--QPYVLMLLSSSQQLRSGVLLECGFWAEEFLIPWHILRESGWPVLIATPDGPPQVDPGSLQADNLAGDERAQI-RSLQAVLSSVQDLRRLNPDLLQAMRGLFIPGGNGPLQDFPKSAAVAHLLCHCEGQGTPVASLCHGGAALLAVA-SGG-RRAFCGYTVSCFRKAEEEDTPLAG----DWPYHLEERLRE-CGYKTDLGPPWSPHWTQDRRLLSGQNPASAAALTRAFVAQL-------- +-------MVLSAASEQQDG-TRQTGVFL---YEPYRAL--AGYDVVVATPQGAPAFDPEGMDPYW-K---A--AQA---LVL--PQTPLNLSEVR-DDFQALLIPGGQGVMVDLLD-ADLHGLLIHFGATDRPVGLVCHAPALLTRMPARQ---NPFAGRSVTSVSGFEEWYIET--F---AKVRGIGDQLDDA-YRHETAL--GRSHAMR-CNLVTSQNPFSGADFNAHFLAAL-------- +--QKKVLFVMSAADTLAEGQLRQTGVFL---YLAYKAI--NGYTVDFATPNGVASIDEESINDYW-K---I--ALK---FVD--SANPITLDKAI-DNYIGLIVPGGQGLMVDLIE-TSIPVLLKQFANENKPTGLICHAPSLLLTIPVAE---NPYIGFEVNAVSPLEEFVIEK--F---PKNRKIARHLRKL-LKYRSGL--KANFAIN-RNLITSQNPFSSSCFNSLYLKAL-------- +--LRKIIFLVTSVTIEPEK--IEIGLWL---ADPYFLR--AKYHIVVASPKGATVPDPTSMQLS--------AF---PNEKKDVYQQIKKLSSLGA-QFDALYAVGGHGLMFDLAFDTN-QALIAEFWEQGKIVAADCAGVRSLANVKL-S-GEHLLRGKRVTGFSEAEVNALG--FG---VIPFFLEDTLVAKRG-YEKAPSVWEPHIVT-GRLITGQNPASAAGVAEAILAAL-------- +--PRRVLIAVTS-AHATE-GKETTGLFI---LHPYNAF--AGFEVDLASETGTYTPDWLSQQPDFLN---TWNFRK----K-SMPK------ELD-SKYGVFFASAGHAALIDYPI-THLQKIAEEVWARGGIVSSVCHGPAIFANVRDL--NEPLIKGKILTGFTSEAEVTMGIMEE---WKKDLVEEIAEKL-AKYTRAP-VWDDYHVF-GHLITGQNPASARSTAKVVVEAL-------- +--SKKAVIALTS-HSGPA-DGKKTGVFS---LYPYHIY--NGFEVDFVSIDGKFGWDDYSLASDFLS---EFNFNV----T-NIKT------QILK-DYKIFYASAGHGCLYDYPT-TGLHEIASKIYENNGVVAAVCHGPVIFEGIMDL--GKKLVEGKSVTAFTDIGEKILKVDDI---KGFDTPETALWKL-AKYLSPI-PFDDYSIT-GRVVTGANPASASSTAIRSVNAL-------- +--PRRALIAITS-AHAPP-EGKETGLFI---LHPFEVF--AGFEVDLVSETGTYQPDWLSQRKDWLN---VWEFRS----KNL-LK------DID--KIIVWLLCFGWTCVFDRLP--GRQGSASNRF--QNLYLGRCHGGAIFPGVIDP--NKSIIDSRRVTGFTTRGEEEENVLDT---WNRPTIEASAASC-ATYVSPP-PWDAFTIT-GRVVTGANP------AEAAVTAF-------- +--SGKILIILSGADSFAKPDEEKTGFFL---ATPLEKI--AGYDVVFASPHGKPSIDPLSESILVYM---RKKIER---MRK--S-APRAFSEIGDRGFKGVFIPGGHAPLTDLGA-PELGRILLHFYRNGKPTAAVCHGPYALLSTRVAPSTGFAYKGYKLTSWSDASESLVEK--L---HIE-KVESALRDA-ADMQTQT-KNLGSVTV-REVVSGANPLAVAELGEKFVEML-------- +--PGTILVVLSDASS-PRKDHEETATFV---AKPLEQL--AGYEVTFASPSGKPSLSPLSNSLLSHL---ARKLQK---QRS--A-SPRSFASVTDDNFEGVFVPGGKTPMMELGE-AELGRLLWGFHNLGKPTAALYHGVYALLSTLHASYSGFAYPGYRITTFSNPDEKSNAP--N---PLISNMEDALKAA-ATLVSEK-QEMGEITH-RELVTAGNFTGAKTLAEEFLEML-------- +---MHILIILSEVSKIEDGMIRDTGYWL---ALPYKFF--KDIKITVATLTGDPVPDPASTEIDSVG---ENPGIQ---LHL--ISRIISLKNLDEKSFDGVFIPGGYAPMVDLVK-EVLGEILWYFHRNSLPTALFCHGPIALLSTQFT-EGGFAYKGYRTTAFSSEEELDTE---L---YLNIDVQEALSLA-MQYQKG--KWTSFLTK-RELITGQNTQSTIEVMFCFFKEL-------- +--DGRVLIILSGADHLRNGTMLKTGYYL---SDPLAYL--AGFSVDFASPGRTPAIDPLSLNF-------KGELAR---VEE--G-RPLAIERITDTDYSGVFVPGGHAPMADLAG-ERMKILFEHFHRGYKPTCLIGHGAAAVIPSITQN-RPWIYRGYRMTCYPDWMDWIAQAV-L---KLPFSISRNLKRA-GIVRHNH-PGRSFVIE-HELLTGQDPRSADRLGRAFVTKL-------- +--PNRILVVMSSAAQIPDGKNHNTGYFL---GVPAKRL--AGYELVIATPRGVPGMDHNSDHDMFFK------IKA---FVV--LSTIQTTEAVAAQAYAALFLPGGHAPMADLMA-PALGEILRQFHAAAKPTALICHAPTALLAAQADPAQDFTYQGYRVTVFANDEEEATEK--T---PMLYYPADALTQG-AQVENG--AMKPNVVR-RELLTGQNPFSDEPFVAQLLEML-------- +--KAHILVYTSSATKIPGGGTHDVGIFL---VEPIEPL--AGHLVEFVSPDGGCVIDPASYRINW-G---RMEFET---TLL--G-NPVKLSDILANSYDVVFIPGGHAPMTDVLHKDQTGELLLHFHKNNKITSAICHGSAALGAAPQVN-GKWIYADYNMTCVSMAAEWLTEDIPF---HMPDYPVRILKRL-GKVHTKM--GRSNVVE-RELITGQDPYSAKELGEKLMKKI-------- +--SGKVLVAGSNANRIEGGGTGPTGQYL---VVPVMAL--AGYDIAFATPDGKPHIDPASDKVVHFD------ARE---FYS--PVKVSTLRALIDDQYDGFFAPGGQAPVVDLMQ-GDLGEILRFFHAHSRPTAFLCHGPIASMAALPRPGKGWPYAGYRMTVYSRSEEKPIEE--Q---QLYFDMPSALTIA-AEVNTG--DFAPHVVE-REMITGQNPRSDHPLASALIAAL-------- +--SGEVLVLLSSETELPGKKSFPSGYYV---GVPADAL--AGYTLTIVTPKGVPKPDVRSIDPLYFG------IKK---LTL--TQNVRSLQDVMQDRYSAIFIPGGHAPLIDLVN-PMVGTTLQHFHRKGKPTAAICHGPITLLAAQKDPAEGWIYHGYKMTIFSNEEEHVFEN--S---KLRYYPANAMKKA-GNMQFA--AWQPHVVI-RELITGQNPYSDHALAQALLKAL-------- +--SGKILLVASSANELTDGRKHPTGYYL---STPAQEF--AGYEVVVATPDGTPALDKNSLTESLFT------AMR---FVH--PSKPKRLGDVVKGSFDALYVPGGHAPMIDLMQ-ADLGKALKHFHENNKVTAMLCHGPIAFSAAMKNSASDWPYKGYNMTVYSTQ-EEYGVE--D---KIEFYMEDALRNA-ANVTVG--PDQPYVVV-RELVTGQNPFSDHQLAKAVLEKL-------- +--VGRILVIASSEGTLENHTRMSTGFFL---AVPTEYL--KGWEIVLATPEGDPIMDQGSNDKKFFQ------AEA---FV-----KPISFQQAIQDRYDALFIPGGHAPMGSLME-QDLGTILKDFHAKEKPTALICHGPAAALAALPDPGKGWIYEGYAMTALSDA-EEWPGE--V---EMPFHLEQALQLA-GKIQVQ--INQSHVVK-RELITGQNPASDLELAKALEKAL-------- +--QGNVLVVLSDAHHLEDGKRYVTGFFL---LQPVKLL--AGHQVTFATPQGAPSVDPSSIDPMHFG---SLKLEN---LKS--PLPVVSLERVEQGHFDAVYVPGGHAPMQDLLA-PQLGRLLTNFHRAGKTTALVCHGPVALLSALPDAQRNWIYAGYRFTVISNDEEAQAK--AV---VMKFYPQTALEQA-GQYSSNR-PWTPHVVI-RELITGQNPASALQVGQALLERL-------- +--SGKVIVVLSGCQSIAKKDDQETGFFM---AQPLIQI--AGYTPVIATPEAKPQMDPMSNSSIWFL---EKNVQS-----K--E-NPRALASFSDGSFAGILIPGGHSPMGDLGS-KALGHILNYFHKARKPTGVICHGPIALLSTTLEN-GEFAYKGYKVTCYANKEEASNEM--M---KLETKVEDALRNA-AEVEVAT-PLMPNVLR-RELVSGEGPSSAWKFGQEYVKLL-------- +--NGRVLVVLSSAHKLTDGRHYPTGFYL---AVPVQAL--AGYEPVFADPQGAVTWDAHSASARYFG------TIQ---FVL--DSHPRTLASVRADTYVGIVVPGGHAPLEDLMT-PDLGEILRAFHNASKTTGLICHGPVALASSLPDAAAGWPYTGYHMTVFSTPEEQFAE---T---HVFFYPATALADA-ATVEEA--IWTPNVVT-RELITAQQPFSDKEFSVALVKAL-------- +--TRSVLVVLSGAKDINSGKSQETGFFL---YVPLNML--AGYRPIFTNPTGTPNMDPLSDHMVWFG---NKADHL---EEE--GSRPIPFSAWGELPIDGLFVPGGHAPMVDLHN-QNLGYIIHHFHRHAKPSGLICHGPVALLSVNLA-DQHWPYTGYKMTAYSDKEEAFNEL--L---RLQLHVEDALKDA-ARYEAR--PLLPNVVE-RELITGQGPTSAWRFGEALLAAL-------- +--EPKVLFLLNS-YYGPD-DGDNTGVNV---YEAFKVF--NGFDIVIASDTGDYGFDDKSFRDPAIV---IFSLMK----KNI-AR------RLN--DYVIVYIPGGYGCSFDFPH-KVVQDFLYRFYETKGIICAVAQANIALAYTTNS--GQALCTNRRVTGCTWKDEVQNGVLNV---LNFYSFGHIAENI-AIFESPV-VEDPFIVE-GQLFTGSNTNSAKGVAMEAVRAV-------- +---MSAVIAVTS-WYGTP-DGGRTGLTY---LHPFNEF--SGYKVTIVSETGQVDFDDLSTSPKFLY---MYDFNI----C-NVKK------EVD--DFNIFYAAGGHGTVMDFET-SGLQRLAEEIYSHGGIVSAVCHGPMVFRGMKD--DGESFIKGKKIAGFMDEGEEAIGLTQW---KKLPFTKESIEAA-GIFHHPT-PWEDYSIA-GRIVTGTNPASAGSVAKLALKVA-------- +--MGKALLVASS-YYGPP-DGKNTGVHF---LTPYEVF--AGLDVDITSEKGTCHFDDNSVDESKLP---VLHFWT----A-NMKR------DVD--EYNIYFVAGGHAALFDLPG-IDLQAIAAQIYKNGGVIAAVCHGPCILPFISDLTNASSIVEGRNVTAFNKAGEESMNMLDI---KNLETMNDAFRKA-AKFIDPA-PNDDFVQS-SRVVTGVNPQSAASTAKAALQAL-------- +---VKVLLAISS-YHGKP-EGSKTGVYF---LEPYTEF--KGYEVTIASETGTFAWDSHSLLFESLSFHFAFLFNK----A-NVKK------DVE--KFDIFFASAGHATLFDYPK-KSLQKIAADTYDNGGVVTAVCHGGAIFENLIDP--GEPLIKGKKVTGFTDSAEKKLFLTNS---HNLVTMEGVAKKE-ATYVSPK-DWDSFTVI-GRLVTGANPQSAEKGAKDTIKTF-------- +--LRRALIAVTS-ANPHP-DGKKTGLFF---LHPFDEL--AGFHVDIASETGTYAYDEHSLEKKFLS---VLHFNK----KSQMFK------DLS--EYGLFFAAGGHGACYDFPN-KHLQAIASDVYGRGGVVAAVCHGPAILGGIHDS--DEPIVKNKTVTGFTTEGELELKVIDQ---DKVHTIEDCMGPT-ARYEAPP-PFENFERI-GRLVTGANPASARDTARDAIKVD-------- +--PPLALIIVTS-YCGPD-DGKKTGAYF---LHPYEAF--NCFQVEFASETGHVGFDEHSIVPPAVT---VLHLMR----ASAVQR------SLD--RYDIVFVAGGHGTLFDMPR-GDIQKFLAGMYEAGKIVAAVCHGPVVLPFVHLK-GGTPLVEGKRITGFTRKGEEMVGVMGT---HNFKTIEDLAESA-AVFKQKE-PFEEYVVL-GHLVTGTNPASARRTAEVAVEAW-------- +--FKRALIAVTD-YNGPP-DGSKTGLFF---YEPFEVF--AGFDVQFVSEDGKYGYDAHSLDPKFAT---AQKYNL----V-GILP------EID--NYSVFFAAGGHGAIFDFVN-PVLGKIAADIYAAGGIVSAVCHGPAIFASIKNE--GQPIVAGKVITGFTAEGEKEMGVSEA---HGKKLVPEIAKEA-AEYRAPP-PFQDFSIT-DRIVTGANPASANSTAEKVVQLF-------- +--LRKALIAITS-YNGPS-DGTKTGLFY---LHPFEAL--AGFEVDLASETGTYGLDEHSIKPPLLG---ALHFNA----KGQLKR------DVD--QYGLFFASAGHGTLYDYPT-HGLIGIAADVYRRGGVVAAVCHGPAILPAVVDA--GGSIIDGKTVTGFTTLAEGALGVLER---DGLQTIEEGAERV-ARYVAPQ-PFEAFSLV-GRVVTGANPASAHLTAENAIAPT-------- +--KRNVLIACSD-YYGPK-DGENTGAFF---LHPYLVF--ACFNVDIVTESGKIQFDDHSVAGPALS---VLEFWR----I-NSKT------EVN--KYDIFFVAGGHATLFDFPK-TNLQKLGTSIYENGGVVAAVCHGPTLLPFMKRQTGSVSIVCGKDVTAFDRVAEDKSKLMEA---YNLEVLDDMLNDA-ANFIKSP-PFGDFVIA-GRLVTGSNPASATSTAKTALRVL-------- +--PRRILMVVSNPAT---LHGGKVGFFAEEMTAAFYAFKHAKHDVELSSPFGEVIFDAHSDPRNPNSPYASLGF-VHHAKFGELLKDTPAAHDKSAADYDAIWVAGGGAPLITFKDDKRLHQLVADFYEQGKVVALVCHGSALLLWAR-LSNGKLLCEGKSWTGFSDKEEDEINSAF-GIKVNEYTIESEAKSIGTRFL-SAAPNAPFAVRDGRLITGQQQHSSTLASQLVLEAL-------- +--KGKILMVVGSPTISQ-QTKWPIGFWAAELTHPMHIFEQAGYTIDITSTAGKIEMDAYSNPTDKSGYSASLGY-LQKKDFQAKLANTRKFTDVKISDYAAIFLVGGQSPMYTFKGNTELQKTFVAFYESGRPAAAVCHSTTLLLEAK-KSNGDLLVNGKTWTGFADAEEKYADDFV-KMKIQPYWIESEARKIDTTFK-VQPAFTPYAIIDGNLVTGQQQNSGALAAEYVVELL-------- +--PKRVAIVIANPAVST-TTGWPVGFWWSELTHPWFVFTERGYDVEIFSPDGRCEADALSDPRDPSGYSESLGF-ISSPKLASLVDNTRPVAEIALDGFDAIVVAGGQAPMFNYARAEALQRIFVAFHEAGKVAAALCHGTALLRYAR-RADGSLLVADKTVTGFANIEEDFADKATWGKHLMPWRIEDELKAIGANYV-QAGLWRAFAVRDGNLITGQQNFSGAETARAVCEAL-------- +--PKRVAIVIANPAIST-TTGWPVGFWWSELTHPWFAFTERGYAVEIFSPEGRCEADALSDPRDPSGYSESLGF-LSSPKLAALVETTRQAAEIDVGSFDAIVVAGGQAPMFSYESATDLQRTFVAFHEAGKVAAALCHGTAILRYAR-RADGALLAAGKTVTGFANAEEDFADKATWGKHLMPWRIEDELRAIGANYV-QAGLWRGFAVRDGNLITGQQNFSGAETARLVCEAL-------- +-SKGKILVVMTNHS-AYPTRSDKTGLWLTELTHFYDVAKAAGYDMDFVSPQGGVVPDERSMKPIYVDKSARKLL--ADRQFMYRLNHTLAPSSIDPTRYKAIYYTGGHGTMWDFPDNKELKNISETIYRQGGIVSAVCHGVGGLLPLVG-ENGKPLISGRTVTGFANKEETLSGIKSQV----PFSLQNSLINHGAKYKQGFLPFTSYVVSDDRIITGQNPQSSKEIAEAVVKR--------- +-ATNKILIIVTNVG-EYEKVGYRTGLWLGELTHFYDYVTDHGYAVDIASPSGGYVPDPESLAHEVLGLGTDKRY--HDREFMNLLENTKKATDLDVEDYDAIYFTGGHGVMFDFR-DGDLGALTARFYETGRIVSAVCHGPAGLLNVPL-STGDPLVKGKNVTGFSWPEEEAAQRADAV----PFSLQDELNKLGANYSIADKPFDPFVVEDGRLITGQNPGSARPVAEALVTK--------- +-SGKRVLIVVTSVG-EYESVGYRTGLWLGELTHFWDYLHEAGGTATIASIAGGPVPDPESLTQDVLELGTGKRY--ADRAFMDLLDTTVSIADVAADDYDAIYLTGGHGVMFDFPDDPHLSRLLREFHETGKVVSAVCHGPAGLLGATL-ANGEYLIAGRNVTGFSWPEEEFAHRADAV----PFSLQARLEERGAVYSFAAEPFAPHVVEDGRLVTGQNPASARPVAEAVVKQ--------- +-ATGKILTIVTNAG-EYEAVGYRTGLWLGELTHFYDHVTGEGFGVDIASPQGGHVPDPESLSRTVLDLGTGERY--RDREFMNLLENTRKVAEIDVEEYDAIYFTGGHGVMFDFR-SDELGAVTAKFYDSGRIVASVCHGAAGLLNVPL-RNGDPLVKGKNVTGFSWREEELAQRADAV----PFSLQDELTALGANYSVADKPFESYVVEDGRLITGQNPGSARAVAEAVVKA--------- +-PTKRILIIVTSTG-EYEKVGYRTGLWLGELTHFYDVAEQAGFELTVASIEGGPVPDPESLAHNVLSLGTDKRY--ADRAFMDTLRDVVAVREVDVDDYDAIYLTGGHGVMFDFHQSQALETLIARFHESGRIVSAVCHGPCGLLDVTL-SDGEPLVKGRNVTGFSWREEELAQRADAV----PYSLEDRLKELGARYSIAAKPFDTHVVEDDRLITGQNPGSARAVAEAVVRR--------- +-RTNRILVIVTSVG-EYRTVGYRTGLWLGELTHFYDVAEAAGFELTIASIDGGPVPDPESLAHNVLGLGTDKRY--ADREFMDKLRQTIGVAQVEVDDYDAIYLTGGHGVMFDFHQSEALETLIARFYESGRIVSAVCHGPCGLLDVTL-TNGDPLVKDKNVTGFSWREEELAQRAEAV----PYSLEERLKELGAVYSIAEKPFATYVVEDTRLITGQNPGSAKAVAEAVVRQ--------- +-GTKRVLAIVTSIG-EYETVGYRTGLWLGELTHFYDVAEQAGFEVTIASIEGGPVPDPESLAHNVLSLGTDKRY--TDRAFMDKLKQTISVSQAEVDDYDAIYLTGGHGVMFDFHQSSALESLIARFYETGRIVSAVCHGPCGLLDVTL-SNGDALVKGKNVTGFSWREEELAQRADAV----PYSLEDRLKELGASYSTAEKPFDTYVVEDSRLITGQNPGSARAVAEAVVRQ--------- +-TRSKVLVIVTSIG-EYEKVGYRTGLWLGELTHFWDVAEEAGLDLRIASIAGGRVPDPESLSHDFLGLGTGKRY--ADRDFMDLLEETVSVADIDAADFDAIYLTGGHGVMFDFPQSRTLAELIAQFYETGKIVSAVCHGPTGLLEVKL-GDGEYLVKDRSVTGFTWKEEELAQRSDAV----PFSLEDELRHRGARFTLAPNPFDPFVVEDGRLITGQNPSSARKVGEAVVRQ--------- +-PTHRILIIVTSAG-EYESAGYRTGLWLGELTHFYDVAEAAGYGLTIASVDGGRVPDPESLAHDVLAQGTAERY--ADRTFMNLLEDTVAVADVRPEEYDAIYLTGGHGTMFDFPRSKALGELIAAFHDQGRVVSAVCHGPCGLLEVTL-ADGRPLLRDREVTGFSWPEEELAQRADAV----PFSLEERLRVLGASYSIAEEPFAPYVVEDGLLITGQNPASATPVAEAVVRA--------- +-ATNKILIIVTNAD-EYQKVGLRTGLWLGELTHFWDFAEEHGFTMDVASPSGGKIPDPESLTRQMLDEGTGKRY--LDRDFMDLLKDTMKVSDASVDDYDAIYLTGGHGVMFDFPQSKDLESLIARFYETGRVVATVCHGAAGLLNVTL-SNGEPLIKGKRVTGFSWPEEELANRAQAV----PYNVQEGLKKLGADYSTAAQPFAPHVVEDGRLITGQNPFSARAVAEAVVKQ--------- +-ATKKILVIVTNVG-EYEKVGMRTGLWLGELTHFWDVAEQAGIPMDIASPLGGKIPDPESLSHEVLALGTEKRY--RDRKFMDLLEDTKKISEVNLEDYDAIYLTGGHGVMFDFPQSRDLEDLMAGFYESDRIVSTVCHGGTGLLNVTL-GNGDPLVKGKRVTGFSWPEEELADRADAV----PYNLQEELQKLGADYRMADRPFEPYVVEDGRLITGQNPGSARGVAEAVVRR--------- +-AVKKILIVLTNTA-AYGERNVATGLWLGEAAEFMDEAIQRGYAVDFVSPKGGYVPDPRSMKPAYVDRAAFALY--RTRDFQEALAHSMHPDDVDPGEYVALYYTGGHGVMWDFPSSEGLERLCLEVYGNGGYLATVCHGIAGLLYVKE-G-SRYLIEGKSITGFTAMEERLSGKSAVI----PFWNEQVAKAHGAVFRKK-RPFAEHAIQDGRIITGQNPESPRAVARLLLKN--------- +--MKKILVAVTNTP-TYGQKNDATGLWLGEAAEFVNEVNRRGFEVDYVSPQGGYVPDPRSMKRAYVDAASFTLY--RSADFQQALAHSLSPDDVDANDYVALYYTGGHGVMWDFPTSEGLAHLGLQIYDNGGYLASVCHGIAGLLFLKD-GDASYLVEGKTITGFTSTEEYLSGHSADI----PFWNEKVAKEHGAVFHKK-RPFASFAIQDSRIITGQNPQSPRAVALLLLKN--------- +--MKKILIALTNTP-TYGEKHAATGLWLGEAAEFVDEVGQRGFEVDYVSPNGGFVPDPRSMKPAYLDQPTFALY--HTPDFQEALARSMSPDDVDAGEYAALYYTGGHGVMWDFPSSEGLARLCLEVYGNGGYLASVCHGIAGLLFVQD-R-GTYLVEGKSITGFTTAEEYLSGKSAAI----PFWNEQVAKAHGAVFCKK-RPFASFAMQDGRIITGQNPESPRAVARLLLEN--------- +-GAGKILMVMTNHD-RYPSRAERTGLWLAELTHVYDALEAAGYAIDFASPNGGAIPDPRSLGWPHADAAAKARL--NDPSFMARLQSTQAVADLDPTVYRAIFYTGGHGTIWDFRGNADLKRVAESIYRSGGIVSAVCHGLAGLLDLQA-EDGKPLLEGRRVTGFSNLEESLSGVKDQV----PYQLQSEMEARGARYEKSLLPFGSFALTDGRLITGQNPRSSKALAQALLAA--------- +-GAKRVLIVMTNHS-EYPTRSDHTGLWLTELTHVYDALKGAGFAVDFVSPEGGVTPDERSLGWLYVDSAAKEHL--NDPAFMAALQSTKAAAEIDPAAYQAIFYAGGHGTMWDFRGNKELKRIAEGIYRDGGIVSSVCHGAAGLLDLED-AKGKPLIEGRRVTGFSNFEETLSGVKDQV----PYALQSEMEAKGARYEKSLLPFRSFTVTDGRIVTGQNPGSSKEVAQALLNA--------- +-MSKRILHVVSNVA-HYADPSQPTGLWLSELTHAHHIFAARGYEQQLVSPKGGVSPEPRSLKWPHADAASKAWR--ADKANAALLAHTARPDEIDPAGFDAIYFTGGHAVMWDYPDDAGLQRLTREIYEHGGIVSSVCHGYCGLLNTKL-SNGSLLVAGRRITGYSWVEEILAGVAKKV----PYNVEQQMRERGARYEKALLPFTSNVVVDGRIVTGQNPQSAKATAEQVVAL--------- +-MSKRILHVVSNVA-HYADPSEATGLWLSELSHAYEVFAEKGWEQQLISPLGGVSPEPRSLKWPNADASARAWL--ASADKRALLAETARPDEVDPTSFDAIYFTGGHAVMWDFPDDAGLQRITREIYEHGGVVSSVCHGYCGLLNTRL-SDGALLVAGRRLTGFSWREEALAGVAGKV----PYNAEEEMRRRGALYEKAWLPFISKVVVDGRLVTGQNPQSAKATARQVASL--------- +-ESKKILIIVTNHE-DYPNREDKTGLWLTELTHFYDEVKEAGFEVDIASPNGGKSPDERSLGWMYIDKEAKKHL--KNPEFTRLLDETLDVSKLNGDDYIAIYFAGGHGTMWDFKDNPDLKLISEQIYNNEGYVTSVCHGAAGLLNLQA-PSGKPLIENKKITGFSNTEEWLAGLTYTV----PFSLEDELKALNPIYKKALFPFVSYAVSDGRIVTGQNPNSGKAVAKELLRL--------- +-QKKKILIMVTNHE-DYPRREDKTGLWLTELTHFYDLIIEADFEVDIASPVGGKTPDERSLGWLYMDKSAKSHL--NEPNFNAMLTNTLDARKLSANDYLAIYFAGGHGTMWDFRNNKDLKRLAEGIHNQGGYITSVCHGAAALLNLES-SEGIPLIAGRHITGFSNTEEWLAGLTDEV----PFSLEDELVALGANYDKRFIPFTSYAIDDGRLITGQNPNSGKAVASNLLKE--------- +-SASKVLVVMTNHD-QYPSRSDRTGLWLTELTHVYDALTAAGYTVDFVSPQGGAVPDQRSLGWPHIDAAAKAHL--DDPAFMARLQSSRAAADIDPAGYRAIFYTGGHGTMWDFRGNKALKRIAEGIYRHGGIVSSVCHGAAGLLDLET-ENGTPLIAGHRVTGFSNFEETLAGVKSQV----PYLLQSELEARGADYEKSLIPFGSFVVTDGRIITGQNPGSSKEVAQALLAA--------- +-PKGKILVVMTNHS-AYPTRSDTTGLWLAELTHFYDVVQAAGYDMDFVSPQGGAVPDERSLKPIYVDQSAKKHL--ADPQFMQRLSNTLAPNAIDTSHYKAIYYTGGHGTMWDFPNNQGLKQISEKIYQQGGVVSAVCHGVGGLLPLQT-LTGQPLIAGRTVTGFANIEETLSGIKSQV----PFSLQDGLVQRGARYKRALFPFTSFVIADDRIITGQNPQSSKEIAEAVVKR--------- +-IKGKILVVMTNHS-AYPTRSDHTGLWLTELTHFYDVAQTAGYKMDFVSPQGGAVPDERSLKSIYVDQSAKKHL--ADPQFMQRLSNTLAPNAIDPSRYKAIYYTGGHGTMWDFPNNQSLKQISEKIYQQGGVVSAVCHGVGGLLPLQT-PTGKALIAGRNVTGFANIEETLSGIKSQV----PFSLQDGLVARGAKYKRSFLPFTSYVIADDRIITGQNPQSSKEIAVAVVER--------- +-SKGKILVVMTNHA-TYPSRSDTTGLWLTELTHFYDVAQAAGYDMDFVSPQGGTVPDERSLKSIYMDASAKAHL--ADPKFVQRLNTTLAPNAIDSAHYQAVYYTGGHGTMWDFPNNQALQKISEKIYQQGGIVSAVCHGVGGLLPLKK-QNGQPLIAGRTVTGFANIEETLSGIKSQV----PFSLQNNLIQHGAQYKRGFFPFTSYVISDDRIITGQNPQSSKEVAEAVIKR--------- +-ENGKILVVMTNHA-TYPTRTDKTGLWLTELTHFYDVAEAAGYDMDFVSPQGGAVPDERSLKSIYLDRAAKAHL--ADPRFMQRLKTTLAPNTIEPKNYKAIYYTGGHGTMWDFPKNKELKNISEKIYQQGGVVSAVCHGVGGLLPLQD-EKGKPLITGKTVTGFANIEETLSGIKSQV----PFSLQNGLIDRGAKYKRALLPFSSYVITDDRIITGQNPQSSKAIAEAVVKK--------- +-LSGKILVVMTNHA-KYPSRSDTTGLWFTELTHFYDAAQATGLQMDFASPAGGEVPDQRSLKSFYLDDSARAHL--ADPAFMARLKATLPAASVNPADYKAIYFTGGHGTLWDFPDNAALKAVSEQIYRQGGIVSAVCHGVSALLPLQD-AEGKSLLTGVPVTGFSDMEETLSGMKSQV----PLFLQDSLVSRGAHYKKALLPFTSYVVSHDRIITGQNPQSSKEIAEAVVKR--------- +-SLGKILVVMTNHS-AYPTRSDHTGLWLTELTHFYDIAQAAGYGMDFVSPQGGAVPDERSLKPIYLDKSAKAHL--ADPKFMQRLNTTLAPKAIDPSRYKAIYYTGGHGTMWDFPKNEDLKKISEQIYQQGGVLSAVCHGVGGLLSLQD-NQGKALIAGRTVTGFANIEETLSGIKSQV----PFSLQDGLVQRGAHYKRAWVPFTSYVVVDDRIITGQNPQSSKEIAEAVVKR--------- +-PLGKILVVMTNHS-AYPTRSDHTGLWLTELTHFYDIAEAAGYEMDFVSPQGGAVPDERSLKPIYMDKSAKAHL--ADPKFMQRLNHTLAPNAIDPSQYKAIYYTGGHGTMWDFPQNQGLKNISEKIYQQGGVLSAVCHGVGGLLPLQD-NNGKALIAGRTVTGFANIEEALSGIKSQV----PFSLQDGLIQRGANYKRAFLPFTSYVIVDDRIITGQNPQSSKAIAQAVVKR--------- +-TNGKILVVMTNHS-AYPSRSDKTGLWLTELTHFYDVALAAGYEMDFVSPLGGEVPDERSLKSIYLDKSARQHL--ADPAFMQRLKTTLIPNAINPTQYKAIYYTGGHGTMWDFPNNKALQNISEQIYRQGGVVSAVCHGVGGLLPLQD-ENGKPLIADRTVTGFANIEETLSGIKSQV----LFSLQNGLIERGAKYKEAFIPFTSYVVSDDRIITGQNPQSSKEIAEAVVKR--------- +-SKGKILVVMTNHD-KYPSREDTTGLWVTELTHFYDVAHKAGYQMDFISPKGGAVPDERSQKWIYMDKQARAYL--ADPAFMSRLNNTLQPNEAKASDYKAIYFTGGHGVMWDFPNNPELTTLAEQIYRQGGVVSAVCHGVAGILSLKD-EQGKALIANRKVTGFSNREESLSGMKKQV----PFFLENQLKSKGAKYSQGFFPFTSYVIVDERIITGQNPQSPREVGEEVVKK--------- +-KDRQILVIMTNHA-SYPSRTDTTGLWLTELTHFTDVVEAAGYTTVFASPKGGVVPDERSLGWLYMDKAAREHL--QSPAFRARLNNTIPIADIDPSRFSVIYFTGGHGVMWDFPENPDLRRVAEKIYNQGGIVSAVCHGVAGLVDLKD-EQGQALIKNRNITGFSNREELLSGMKNQV----PFFLEDRLVGQGARYRKAWLPFTPFAITDGRLVTGQNPQSPRAVAEAVMAL--------- +-TKGKILVVMTNHA-KYPSREDTTGLWVTELTHFYDVARQAGYEMDFISPKGGVVPDERSQKWIYMDKEAHAHL--ADKAFMSRLNHTMKPSDVKASDYKAIYFTGGHGVMWDFPNNPELTLLSEQIYRQGGVVSAVCHGVAGLLALKD-EQGQPLIANRKVTGFSNIEESLSGMKKQV----PFFLEDNLKSKGADYKQGLFPFTSYVIVDDRIITGQNPQSPREVGEEVVKR--------- +-SQGKILVVMTNHS-KYPSREDTTGLWVTELTHFYDVAQQAGYEMDFVSPQGGAVPDARSQKWIYMNKAARVHL--ADPAFMQQLNHTLNPSEVNAADYKAIYFTGGHGVMWDFPNNPELTALAEQIYRQGGVVSAVCHGVAGILALKD-EQGQPLIGNRKVTGFSNREESLSGMKKQV----PFFLEDQLKSKGARYSQGFLPFTSYVVVDDRIITGQNPQSPREVGVEVVKR--------- +-KNSQILVIMTNHA-RYPSRTDSTGLWLTELTHFTDVVEAAGYSTVFASPKGGAVPDERSLGWLYMDKAAREHL--QSPAFRARLQNTLPIADIDPSQFGVIYFTGGHGVMWDFPNNPDLRRVAETIYNQGGIVSAVCHGVAGLLDLKD-EKGQLIIKGKNITGFSDREELFSGMKSQV----PFFLEDKLVSQGARYRKGWLPFTSFAITDGRLVTGQNPQSPKAVAEAVMAV--------- +-SKGNVLFIVSNQH-YYGNTDMNAANHFGEIVFAYDVLVKEGYQVDFVSPKGGAIPGYLSTSDSIQKYIYDFDL------MRKL-KNTLKPEAITSSDYKAVYYVGGGAAMFGVPEDENIQAITMSIYNNNGIVSAVCHGTAGIVNLKT-KDGNYLYKGKQVNGFPDLFENKD-YYKTF----PFSIEGIITERGGNFSYSEEGWDNYFKVDDRLITGQDPTASASVAKKIIQT--------- +-SQDKILFVTSNQS-TYGDTTLKTANHFAEIVLAYDVFIKSGYQVDFVSPEGGEIPGYINTSDPIQKYLDDLDF------MNLF-KNTYSPEAINAKDYKAVYYSGGGAAMFGVPENKAIQDISRKIYENTGIVSAICHGTAGIVNLKL-TNGKYVYEEKEVNGFADAFENKN-YYKTF----PFSIEEAITKNGGNFTYSKKGWDNHYIVDGRLITGQDPTASVSVAKQVVAM--------- +--------------------MLPASISFGEVVHAWDTFKAAGYVVDFVSPDGGDVPLDEYVSEDVA-RIEDEEV------MRGL-RNTAKPEQIDPARYRAVYYVGGSNAIYGVPEHSVLQSIAMHVYENGGVISAVCHGTAGLVNLKL-ASGQNLVAGKRISGFPEEHERQD-YFKEF----PFLIRKTVEDRGGVFHALD-SEDPYIEIDGRVVTGQNYASAKPVAEAVVDV--------- +-SPDRILFIIASSK-VHGTSTLPASISFGEVVHAWDVFNAAGYAVDMVSPDGGAVPLDDYVSPDVA-RLHDARI------MDPL-RTTFTPAQVDAARYRAVYYVGGSNAMYGVPEHPALQRIALQVYENGGVVSAVCHGTAGIVNLRL-ASGDYLIAGKRVSGFPEEHEQQG-YFKQF----PFLIGTTVRARGGVFHAVD-GEAPHIQVDGRLVTGQNYASAAPVARAVVAA--------- +-VKGKVLIIISS---------DQHGFWLPEVVEPYKLLEQAEFEIDIASPKGGKGISGSSRLSGKDSW-----F--KQSSLPEKLEQSIELKQVISRQYRAVYFAGGAGPMFDLVENQEAQRVTREIYENGGIISADCHGPAALINVKL-SDGSRLISGRKLTAKANIEEGRW---NNY----PFLLEDKIVSLGGIYTS-AAKGKEHVIVDGRLITGQNPASAAPMTKALILH--------- +-KGIKVLIIVSS---------DRHGFWLPEVVEPYQLLANAGYLIDIASPKGGQGRSGSSRLTEQHAW-----F--EQSPLKRQLQHSMPLADVKPQAYAAVYFAGGAGPMFDLPDNKLVQQITRDIYEAGGIVSADCHGPAALINVML-SDGKRLVSGRQITAKANSEEGRW---NNY----PFLLEDKIKALGGKYLA-AAKNQPHVVVDGRLITGQNPASAIPVAKSLLRQ--------- +-NSGKVLFILSA---------DKHGYYLPEVVEPYQHIINNGYSVEFASPDGRPGRVAYKLLSKQAQD-----Y--KIMRKNSNIDLPTPLKSIQPKDYIAFYVPGGAGPMFDLAGHPEMARLSLAFLAQDKIISAVCHGPAAFVDIKN-ADGNYLVSGLKVTAKSNAEEGRW---QNY----AFLLQDKLQAQGAQFTY-TSPGEPYVIHDNGVLTGQNPKSALPTAIVLIKL--------- +-KQGKILIIISS---------DQHGFWLPEVLEPYRLLADAGYAIDIASPLGGDGYRGVSRLSKEQQW-----F--NNADLKQQLQQTKPLSAVVATAYLAVYFAGGSGPMFDLVNNKQAMAITRDIYEAGGIVSADCHGPAALINVTL-ANGQRLIAGKKLTAKANIEEGSW---NNY----PFLLEDKIADVGGLYSA-KGKNQVHVVVDRRLITGQNPASALPMAKRLLAQ--------- +-MSPSILVVLTSHA-DLADTGKKTGWYLSEFSHPHHVFASSPPKITVASPRGGAAPDQSSIEAAKDDISVEFLH--KQSALWEATTPLSQILQQGIDSYDALFFPGGHGPMFDLAGDKESQEIVKRFWEAGKIVSAVCHGPAALVNVKL-SNGDYLLKGKKVTAFSNSEEDGVGLSEKM----PFMLETRIKEVGAEYEKAGQDWGEKLVVDGKLITGQNPASAKAVGEAILKV--------- +-MNKRILIIVSNAN-AIGPNNRRTGIFLPEVAHPYAEFDKANYQIDFASLTGDTPYDALNLANDPDNA-----F--LTGKGWEAMQKAVKLSNVDAGKYDAIFVPGGLAPMVDMPENELLKKVIKETYERNAVVGAVCHGPVSLLNVKL-SNGNYLVKDKNITSFTDEEERGY---ADV----PFLLETALTKQGAKFHA-AAIWSAHSIADGNLVTGQNPASAKGVAEKMIVI--------- +--MKKVLIIVSNAN-TIGPNNRRTGNFLPEVAHPYAEFDRAQYQIDFASLNGDTPYDDLQSAADPDNA-----F--LTGKGWAAMQKAVKLSDVDVSTYDAIFMPGGLAPMVDMPDNALLKQVVKETYERNAVVGAVCHGPVSLLNVKL-SDGSYLVNGKNISSFTTEEEDAY---ADV----PFDLQTALTQQGAIYHT-VEPWAPFSIADGNLVTGQNPASGKGVAQKMIKI--------- +--MKKVLIIVSNAN-TIGPNNRRTGTFLPEVAHPYAEFARAGYQIDFASLTGDTPYDALNLASDPDND-----F--LTGKGWEDMQKARKLSDVDVTGYDATFVPGGLAPMVDMPEDPLLKQVIKETYERGAVVGAVCHGPVSFLNVKL-SDGSYILNGKNIASFTNEEEDNY---DDV----PFRLETALVEQGAIFHA-AEPWSANSIADGRIVTGQNPASAKGVAEKMIAV--------- +-MSKRILFIVSNAK-FIGPDNRKTGVFLDEVAHPYVEFEDAGYQIDFASLTGEVPHDNMQAKDEASNR-----F--LKEAGWEKMQHNSKLSEVDVSIYNAIFVPGGLAPMVDMPENELLKEVIAETYERKAIVGAVCHGPVSLLNVKL-SDGTFLLKDKNITSFTNEEENNY---ADV----PFALESALTEQGAKFHA-AAPWSDHSIADDNLVTGQNPASARGTAQKMIAL--------- +-MSKKILFIVSNAS-FIGPNNRQTGVFLDEVAHPYVEFDDAHYQIDFASITGGVPADNLTASEESSNR-----F--IKDGGLAKMQHNRKLSDVDTSGYDAVFVPGGLAPMVDMPEDPLLKKVIAGFYDSGKIVGAVCHGPVSLLNVRL-NDGSYLIAGKNITSFTNEEEDNY---NDV----PFELETALTNQGAKFHA-AAPWSSNSIADGRLVTGQNPASAKGVAQKMIAL--------- +-MSKRILIIVSNAK-VIGPKNRKTGVFLDEVAHPYVAFDDAGYQIDFASITGAVPADNMEAKDEESNR-----F--LQKGGWEKMQHNTKLADVDASIYDAIFVPGGLAPMVDMPEDALLKKVIAETYERGAVVGAVCHGPVSLLNVTL-SDGTYLVKDKNITSFTDKEENHY---EDV----PFLLESALTEQGGRFHA-ASPWSDNSIADGNLVTGQNPASARGTALKVIEI--------- +-MSKKILIIVSNAC-VIGPNNRRTGNFLPEVAHPYAEFDRAKYQIDFASLTGDTPFDALNLADDPDNA-----F--LVGKGWASMQKAKKLSDVEVSQYDAIFMPGGLAPMVDMPEHPLLKKVVKETYERGAVVGAVCHGPASLLNVKL-SNDTLLLAGKNISSFTNEEEENY---ADV----PFELETALTKQGALFHK-TVPWQAFSIADKNLVTGQNPASAKGVAEKMIAL--------- +-MKKKILIIVSNAN-AIGPNNRRTGTFLPEVAHPYADFDKAGFQIDFASLTGETPYDGLDLAGDPDNK-----F--LTGDGWAEMQKATKLSNVDTTVYDAVFTPGGLAPMVDMPEHQTLKKVLAETYERGAVVGAVCHGPVSLLNVKL-SNGKYLVDGKNITSFTTEEESMY---ADV----PFDLQTELSKQGAIFHA-ETAWSAHSIADGNLVTGQNPESARGVGEKIVAL--------- +-MKKKILIIVSNAN-SIGPNNRRTGTFLPEVAHPYADFDKAGFQIDFASLTGETPYDGLDLAGDPGNK-----F--LTGDGWAEMQKATKLSYVDTTVYDAVFTPGGLAPMVDMPEHQTLKKVLAETYERGAVVGAVCHGPVSLLNVKL-SNGKYLVDGKNITSFTTEEESMY---ADV----PFDLQTELSKQGAIFHA-ETAWSAHSIADGNLVTGQNPESARGVGEKIVAS--------- +-MKKNILIIVSNAN-SIGPENRRTGIFLPEVAHPYAEFTKAGYQIDFASLTGDTPYDALNLADDPANA-----F--LTGQGWADMQNAAKLSDVNDTLYDAVFVPGGLAPMVDMPEHALLKKVIADAYERKAVVGAVCHGPVSLLNVKL-SDGSFLVSGKNITGFTDEEEENY---ADV----PFLLETALSNQGAIFHA-ATPWSENSIADGNLVTGQNPASAKGVAEKMMVI--------- +-MKKNILIIVSNAH-EIGASKRRTGIFLPEVAHPYAEFEKAGYTIDFASLTGETPYDAVNLANDPANA-----F--LTGEGWAAMQKATKLSEVNAGVYDAVFIPGGLAPMVDMAEHPLLKKILAETYERNAVLGAVCHGPVSLLNVKL-NDGSYLVNGKNVTGFTNEEEENY---ADV----PFLLETALTAQGAIVHA-ATPWSENSITDGNLVTGQNPASAKAVAEKMIEI--------- +-MNAKVLIIVSNTS-SIGPNHRRTGTFLSEVAHPYAEFEKAGYQIDFASLTGESPFDALNLADDPDNK-----F--LTGKGWEEMHNATKLSNVNLNDYDAVFVPGGLAPMVDMPEADEIKKVIAEFYESDRIVGAVCHGPVSLLNVKL-SDGSYLVNGKNITSFTTEEEDNY---PDV----PFDLQTALTEQGAIFHD-AEPWSANSIVDGNLVTGQNPASAKGVGEKIVAL--------- +-MKPRVLIIVSNAH-SIGPNNRRTGTFLPEVAHPYAEFQKAGYKIDFASLTGEVPYDALNLANDPDNQ-----F--LTGPGWEDMQKASLLSEINADEYDAVFIPGGLAPMVDMPEAPLLKKVIAQVYENDGVVGAVCHGPVSFLNVVL-SDGTYLVEGKNITSFTTEEEDQY---ADV----PFDLQAALSNQGAVFHA-AEPWSSHSIADGNIVTGQNPASAKEVGEKMIAV--------- +-MKKNILIIVSNAN-SIGPNNRRTGTFLSEVAHPYAEFEKAGYQVDFASLSGGVPYDALNLADDPDNR-----F--LTGTGWADMQQAKQLEKVDVKAYDAIFIPGGLAPMVDMPNAPALKQVIADTYERGAVVGAVCHGPVSMLNVKL-KDGSFLVNGKNIAAFTTEEEDNY---ADV----PFDLQEALTSQGAIFHA-AAPWSANSIADGNLVTGQNPASAKGVGEKIIAI--------- +-MKPKVLIIVSNAN-TIGPNNRRTGTFLPEVAHPYAEFEKADYEIDFVSLTGESPFDALNLADDPDNK-----F--LTGKGWEKMHSAPKLSSINTDDYDAVFIPGGLAPMVDMPENTELKKIIAGFYESNRIVGAVCHGPVSLLNVKL-SDGNYLVNGKNIASFTTEEEDNY---NDV----PFDLQTALTEQGAIFHA-AEPWSANSIVDGNLVTGQNPASAKGVGEKMVTL--------- +-MNKKILIIVSNAN-AIGPKNRRTGTFLPEVAHPYAEFEKAGYQIDFASLTGETPYDALNLASDPDNN-----F--LTGKGWEDMQQGTQLSAVDASIYDAIFIPGGLAPMVDMPEAPLLKKVIAETYERNAVVGAVCHGPVSLLNVKL-SDGSFLVNGKNITSFTTEEEDHY---ADV----PFDLQTALAAQGAIFHT-AAPWADNSIADGNLVTGQNPASAKAVGEKIVAI--------- +-MKKKILIIASNAN-TIGPHNRRTGTFLSEVAHPYAEFDRAGYQVDFATLSGDTPYDALNLADDPDNK-----F--LTGNGWAAMQKAVKLSDVDVSKYDAVFVPGGLAPMVDMPEAPLLKKVIKETWERGAVVSAVCHGPVSLLNVKL-SDGSYLVNGKNITSFSTAEEDNY---KDV----PFDLQTALTGQGAIYHV-AAPWSANSIADGRLVTGQNPASAKGVAEKVIAI--------- +-QGDKILFIVSNAS-FYGDSDIATGNSFSEITNAYTTFKNAGYTVDFVSPNGGSIPTYIDTLDPLQKLVYNKDF------MYAL-KHTKKPIEIIAKNYKAVHYIGGGSAMYGVPENKDIQKIAMEIYEHNGIISSVCHGTAGIVNLKT-KDGRYVYEGKIVNGYPDSFEKKD-YFKHW----PFLIQKTIEERGGIFQFSKRNT-SQVEVQGNLITGQNYLSSKDVALQIIER--------- +-NGDKILFIVSNAS-FHGTSKLPTGNSFSEIVNAYDTFKKEGFTVDFVSPYGGSIPAYINTSDALQKLLYSEYF------MYAL-KHTKKPKEIIAKDYKAVHYIGGGSAMYDVPKNKEIQKITMTIFEYNGIVSSVCHGTAGIVDLKT-KDGKYLVNNKIISGYPEAYEKEG-YFKQF----PFLIQKTIEERGGIFKYSPRNS-VHVEVQGNVITGQNYLSSKDVALKIIEN--------- +-ENKKVLFVITSHD-QMGERKTKTGYWLEELAAPYEILSQAGANITLASPMGGKPPDPASLKSASQTYTKIFKH--DQQAQEALSHT-LVLTSVKAEDYDAVFYPGGHGPLYDLADNQDSIRLIEDFAKAKKPVTVLCHSPSVLKNVKD-FKGEFLVSNRKVTSFSDSEEAGAHLKHVL----PFFTEDMLKEEGALYQR-KPNWEAFSVQDGILLSGQNPQSSQLVAEKLVEI--------- +-EMPSALFVVTAAD-KWDGSARPTGYWAEELIAPHRVFKNAGWDIDFATPNAKAPVDEYSLEVLSEGRAEQENY--LAEIGPDLEDP-LNLADVKEADYDLVFYPGGHGPMEDLAYDQDSAKLLQERIESGRALSLVCHAPAALLAL-D-NDN-WPLKGYTMTGFTNAEEGEE---AAA----KWVVETRLRELGADFKQ-TDPMQPYVEVDRNLYTGQNPASSEPLAQRILRD--------- +--MPSVLFVVTAAE-EWDGTKRPTGYWAEELIAPHRAFQGAGWDIHFATPGAKAPVDEYSLEVLPDNRMAQENY--LAELGVALEHP-MNLADVNEEDYDLIFYPGGHGPMEDLAYDQDSAKLLQARMDSGRKLALLCHAPAAMLAV-D-NEN-WPFKGYKMTAFSNAEEGED---AAA----KWALETRLRELGADYQE-TDPMSPNVIVDRNLYTGQNPASSEPLAQRILRD--------- +--MTSILFVVTAAD-KWDGTERETGFWAEELIAPHRVFSTAGWDITFATPGGKAPVDEMSLDVLPEQQMAQENY--LAEIGVALEDP-LDLAEVNPDDYDAVFYPGGHGPMEDLSSDAESARIIRAFLDNGRPLGLVCHAPAALLATAE-GDN-WPFKGWEMTGFSDTEEGDS---DVA----KWTLESRLRELGAKYEA-ADPLQPNVVVDRNLYTGQNPASSEPLAQKMMRD--------- +-KVMKVVMILTSHD-QLGDTGRKTGFWLEELAAPYYVFKEAGYEITLASPEGGQPPDPKSNEPAFQTDTRRFEA--DAEAREALANT-VKLADISQADFDTVFYPGGHGPMWDLAESPVSAALIESFLAANKPVALVCHAPGVLRHVKT-PNGRPLVEGKKVTGFTNSEEAAVGLTDVV----PFLVEDELQAKGGIYSK-GPDWGPYFVQDGLLITGQNPASSAGAARRLVEE--------- +-SAKKVLIVVSNTV-DMDPEKHDARNNLWEVAPPYHIFLSHGFEVDFVSPKGGSVEMMDPLGISSYTK--YEG-------FLDKANNSLSPAQVNPENYWAVYIGGGYGVMFDVANNAKIHAIISRVYESGGVIGVGGHGSAGIANVTL-SNGEFLVKGKKVAGFPNSTETSW-QGALL----PFLIESQLNKNGAIALN-KQTLKHAVVVNQRIVSTMFLPSAALVAKEMIIL--------- +-DRKKVLIITSNLV-DMDPDKSDARNNLWEVAPPYHVFVSHGVDVDFVSPKGGKVEQMEAYGISAYTK--YEG-------FTEKTNNTLSPSQIDPSQYWGVYIGGGYGPLFDVASNKALQKIIADIYEAGGIVGSAGHGAGAFSNVKL-SSGEFMIKGKKVAGFPNSTERRW-QGTLL----PFLVEEQLNKNGAIAQN-KTTMKKAVIKDERIVSTMFMYSAAIVAKEMMLA--------- +-PSKKVLIVASNMI-DMDPEKHDARNNLWEFAPPYHIFVSHGFEVDFVSPKGGEVQMMDPLGISSYTK--HEG-------FLEKANSSISPSQINPNNYWAVFIGGGYGVMFDVADNQKIHAIIRSIYETGGVIGVGGHGSAGIVNVSL-SNGEFLVKGKKIAGFPNSTEESW-QGTLL----PFLIESQLNKNGAIAQN-KKTLKHAVVTDQRIISTMFLPSAALVAKEMIIL--------- +-EAKKLLIIASNVT-DMDKEQHDARNNLWEVAPPYHVFVSHGYEVDFSSPKGGKLEMMDPVGISSYTK--YQG-------FLDKANNSLPATKVNPDDYWGVYIGGGYGPLFDVATNPELLNVMAEVYQNGGIIGSGGHGAGGFANVRL-ANGEFLVKNKKVAGFPDSTEKVW-QGSLL----PFLVESQLNKNGAIAQN-KKTLKHQVVIDSRIVSTMFLPSAALVAKEMILL--------- +-EPKKILIVASNVT-DMDAEKHDARNNLWEVAPPYHVFVSHGYEVDFASPKGGKLEMMDPVGISSYTK--YEA-------FQEKTNHSLPATKVNPDDYWGVYIGGGYGPLFDVATDPELLAIMAKIYQDGGIVGSGGHGAGAFANVRL-ANGEFLVKDKKIAGFPNSTEKTW-QGSLL----PFMVESQLNKNGAIAQN-KKTLKHQVIIDSRIVSTMFLPSAALVAKEMILL--------- +-PAKKVLIIVSNME-NMDPEKHDARNNLWEVAPPYHVFVSHGFDVDFVSPQGGKVPMMDPLGISSYTK--YEN-------FLGKANSSLKPEDVNPDDYWGVYIGGGYGPVFDVASNKEIQSIIARVYESGGVVGTGGHGAAGIANVKL-ASGQFLVKGKKIAGFPNSTEKSW-QGTLL----PFLIESQLNKNGAFAQN-KETLKHDVVIDQRVVTTMFLPSAALVAKEMIIT--------- +-EAKKILIVASNMQ-DMDPEQHDARNNLWEYAPPYHIFVSHGYEVDFVSPSGGPVAMMDPLGISSYTK--YEH-------FLDKANASLTPKQVNPEDYAAVFIGGGYGTLFDVASNKTLLDIMAKIYENGGVLGSCGHGAGGFANVQL-SDGKFLVNAKRVAGFPDSTEKEW-QGTLL----PFLVEEQLRKNSAVIVN-KENIKHEVIIDQRIVSTMFLPSAALVAKEMIIL--------- +-PVKKVLIVASNMV-DMDAEKHEARNDLFEFAPPYHVFISHGYDVDFVSPEGGAVPMRDPLGIASYTK--YEN-------FLDKANNTLTPAQVKPEQYWAVFSGGGYGVMFDVAQNVEIQAIIAKVYEAGGIVGVGGHGAASIANVKL-SGGDYLVKGKKVAGFPNSTELEW-HGTLL----PFLIESRLRDNGALAQN-KDTLKHDVVIDQRIVSTMFLPSAALVAKEMIIL--------- +-AQKKVLFVASNVL-HMDPEQHDARNNLWEYAPPFHIFVIHGYEVDFVSPQGGRVEMMEPIGISSYAA--HQN-------FLGKTANTLKPSEVDVDQYQAVYVGGGYGTLFDVASNEKLMSIIGEVYESGGVVGGCGHGPGGFANATM-SNGVYLVKDKRVAGFPNSTERSW-QGKLL----PFLVEDQLLKNGALAQN-KQTLKNAVVMDQRIVSSMFLPSAALVAEEMVGL--------- +-EPQKVLIVVSNQV-DMDPEQHDARNDLFEVAPPFHVFLSHGYEVDFVSPDGGPVFMRDPLGISSYAA--YEG-------FLERTEATLSPEQVDPEAYWGVFIGGGYGVMFDVAADEETQALIAGIHEAGGILGASGHGSAGFANVRL-STGAYLVDGKRIAGFPDSTETTW-QGTLL----PFLLETRLNEHGAIALN-KESLQNEVVIDQRIVTTMFLPSAALVAKEMILL--------- +-EKGRVLIIVSNTE-HMDPEKHFAGNNLWEVAPPYHVFVSHGYKVDFVSPTGGEVPSMDPVGISSYAK--YEN-------FYGNVENSLTPESVDSKNYDAVFIGGGYGPLFDVANNKGLLKIIADIYENGGIVGGCGHGPGALANVKL-GNGEFMVKGKMVTGFPNSTEVTW-EGTLL----PAMLEDQLRKNGALFQT-KSDLKHDVVIDARIVTTMFLPSAAIVAKEMISE--------- +-DAKKILIIASNLE-DMDADKHDARNNLWEYAPPYHVFVSHGYAVDFASPAGGAVPMMDPLGISSYTK--YEG-------FLDRANSSLNPDQVNPENYVAVFIGGGYGTLFDVASNQKLLDIMAKIYESGGVIGSSGHGAGAFANVKL-KNGKFLVQGKRVAGFPNSTEVEW-QGTLL----PFLVEDQLRKNGALAIN-KGNIKHEVIIDARIVSTMFLPPATLVAKEMLIL--------- +-PTKKVLIIASNKV-DMDPEKHDARNNLWEFAPPYHVFVSHGFEVDFVSPKGGNVEMMDPLGISSYTK--YEG-------FLEKANSSFTPSQIDPNDYWGVFIGGGYGVMFDVANNKAIHSIISRIYESRGIIGVGGHGSAGIANVTL-SNGQFLVKGKKVAGFPNSTETSW-QGTLL----PFLIENQLNKNGAIAQN-KQTLKNAVITDQRIISTMFLPSAALVAKEMIML--------- +-NAKKVLIIASNLT-DMDPEKHEARNDLWEYAPPYHVFVSHGYDVDFASPLGGTVPMRDPLGISSYTK--YEG-------FLSKANNSLTPKQVNASEYSAVFIGGGYGNVFDVASNKDLLGIIAKIYESGGVIGSVGHGAGAFANAML-SSGQPLVKGKRIAGFPNSTEKEW-QGRLL----PFLVEERLKEKGAITVN-KDNIKHDVIIDDRIVSTMFLPSAALVAKEMLIL--------- +--PRKALIAITSAHAPLYPEGKETGLFITEALHPFKVFRAAGFEVDLVSETGHWQPDWLSVQKDWLPEDDRKIYEDTSSEFRRKLDNLLKPSDVKWEDYGLFFASAGHASLIDYPTATGLQALATNIYQNAGIMSAVCHGGAIFLGLSDPANKEPMIKGKTVTGFTNRGEEEEGILDVIKSWDKLTIEAGAAACGAN---------------------------------------------- +-------------------------------------------------------------------------FYDSYTVHHKLLSTLKRAADVDPSQYGLFFASAGHGTLYDYPTAHGLIGIAADVYRRGGVVAAVCHGPAILPAVVDAATGGSIIDGKTVTGFTTLAEGALGVLERIRADGLQTIEEGAERVGARYVAPQKPFEAFSLVDGQVVTGANPASAHLTAENA------------ +-LPRKALIAVSSAHPPFYLDGKKTGLSFPEALHPFNELVEAGFDVDIASETGTFAYDDHSLDSHNLSHEDQRILQSFDYPFHHKMKQIFKAGDLSAHEYGLFFAAGGHGAMYDFPHARHLQAIAEDIYDRGGVIGAVDQAPVILAGIRS-PDGEPLLKGKEITGFPTKGEVELKVIDKIREDNLKTVEEIAQDLDAHYLPPAHNFDDFSHIDSRIVTGANATSATGTV--------------- +---PKVLFVLTSH-DKMGDTDNPTGWYLPEFAHPYYKLAP-HAEITIASPKGGEAPLDPSSVEMFKEAESTRFLKEKEAL----WKNTEKLELGRETEFDAIFYVGGHGPMFDLATDQTSHSLIRTFYESNRIVSAVCHGPAALANAKLSD-GSYLVAGKDVTGFTNVEEDQVGL----SSVMPFLLESKLVENGGQFVQATEPWGAKVVNSGRLITGQNPNSAGPVGEAILK---------- +---PKIIFILSSN---------RAGWYLPEFAHPYDVLSP-HVDLVIASPLGGEAPIDMSSVELFKGASCADFFATRKPL----WQNTQKLESGHAKEYDAIFYVGGHGPMFDLATDKISKKLILEFVDASLTISAVCHGVAALTDVPTKN-G-QLIAGRAVTGFSNLEEKL-IG----EHSVPFLLEDALRAKTDKYEKSDEAWAPKVISTTLLITGQNPASAHAVAVELLK---------- +---PKILTILSSD---------RAGWYLPEFAHPYNVLSP-HVDLVIGSPLGGEAPIDMSSVELFKGASCADFFATKKSL----WQNTQKLESGHAKEYVAIFYVGGHGPMFDLATDEISKKLILEFVEASLTISAVCHGVAALTDVPTTN-G-QLIAGRAVTGFSNLEENL-IG----EHAVPFLLEDVLRAKTDKYEKSDEAWAPKVISTTLLITGQNPGSAHAIAVEILK---------- +---PKILFVLSSH---------EAGWYLPEFAHPYQVLSP-YVEAVIASPTGT-SVVDPISVKLFKDAYCQEFYNTKKDL----WTSTEKLSSGRANEFDVIFVVGGFGPMYDLATDPDSIQLIREFHDADRIIVALCHGSAALVDVKLAD-GTPLIAGQRVTGFSDTEEEQAYV----PPGMPFSLEQALNKSGGKYEKSTEAWSPHVIVEQKLLFGQNPNSAHPLGEELLK---------- +---PKILFVLSSH---------SAGWYLPEFAHPYQVLAP-HVEVFVASPDGT-STVDPISVKLFKDAYCQEFYNTKQDL----WTTTEKLSSGRAKDFDVIFVVGGFGPMYDLATDATSIQLLREFHDAGRIIVALCHGSAALVNVKLAD-GTPILAGHQVTGFSNLEEEQATV----PPGMPFSLEDALNKSGDKYEKSGEAWSPHVIVDPKLLFGQNPASAHPLGEKLLE---------- +---QKILFVLTSA-DKLLTGE-PTGWYLPEAAHPYYVLSP-HFVIDFAAPAGPNPPIDPGSVEMFKQTTSVKFLNDEAVKA--KLSTTLRLSEVKVDDYIAVFYVGGHGPVIDLAVSPENISLGGQFFRTGKLVGAVCHGTAALAGVTTAD-GTSIFKGKRVTGFSNVEEEQVGK----VKAIPFLLEDVIKTKGGFYEKASAPWGAHVVAD-QLYTGQNPASAGPLAEEILK---------- +---NKILFVFTSV-NKTLTGE-PTGWYLPEAAHPYYVLAP-HFDIDFAAPAGPNPPLDPVSKEMFQDEESQKFLTDKVPQE--KLANAKKLADVNPDDYAAVFYVGGHGPVIDLATDPTNVKLASKFWQQGKIVSAVCHGPAALVGATDAS-GQSIFKGRRATCFTYDEELQVKK----VDSIPFQPEHKIVELGGKFEKT-EPWGVKVVAD-QLYTGQNPASAGPLGQELLK---------- +---SRILFVYTSA-DKTLRGH-QTGWYLPEAAHPYHVLAP-HFPIDFASPAGPNPPIDQGSIEMFKDEQSVKFLEDPAVKA--LLANAKPLKDVNVDEYIAIFYVGGHGPVLDLATDHANIELANKFYRSGKIVSAVCHGPAALVGVTGAD-GKSIFDGKAATCLTNVEEEQVDK----VKDIPFLVEDRIVSLGGKFEKA-EPWGVKVVQS-TLLTGQNPASAGPLGEAILK---------- +---PRVLFVLTSH-SALGTSGKPTGWYLPEFAHPYHQLQK-VADITVASPAGGAAPVDPGSVESWKQEVSSQFWEKQSAL----WKNTEKLSNGKAPDFVAIFYVGGHGPMYDLATDADSIQLIREFFESGKVVGAVCHGSAALVNVKLSD-GSYLVADAEVTGFSNDEEDQIGL----SQFMPFMLETELNKSNGKYIKADRPWGECVAVS-RLITGQNPMSATATGNALVS---------- +---QKLLVVLTSQ-DVLPTRAMKTGWYLPELVHPYNDLDG-HVELVVASPKGGEAPVDPYSIEDSKNEASQRFFKEKGHV----WKNTQKLESGKSAEYVGIFFVGGHGPMFDLAVDPTSHALIREFYEANKLVSAVCHGPAALVNVKLSD-GTYMVQGQTVTGFSNAEEDAYKF----TDAMPFLLEDKLKEHGGQYEKADQLFGVKVVTSGNLITGQNPPSAGVIGKVLLQ---------- +--------------------------------HSYYKLAP-VFDIMVSSAVGDEALLSPQSIEATKEPGCVVFLKENSSV----WKNTAKLDTGKASEFAGIFCVGGHGR--------------AGFLEAGKVVSAVCHGPAALANVKLSN-GTYLIAEQNFIGISDVEEDIIQF----SRDMSFLLETELREYGGIYEKAVGRFGVKVLTSGKLYTGQNTSSSALQYLF------------- +---PKVLFVLTSA-DKMPTGE-STGWWLSEFAHPYTILAP-HANITIASPKGGPAPLDSNSVAHAKNSVSATFLSTQSSL----WETTVPLSTGHAGEYAAIFFVGGHGPMVDLANDPESIALIREFYSADKVIAAVCHGPAALINVTLDD-GRHLLEGLKVTGFTDSEEANTGV------KVPFSLQQRLDQSGGGFVRGE-DWKEMVE-VGKLITGQNPGSAAAVGGAILE---------- +---PKFVFVLSSQ-SILPSRGTPTGWYLPELVHPYNALAP-LFDIIVSSPNGGEAPLDPYSVEATKEPECVAFLKEKSHI----WKNTVKLQSGNASEFAGIFYVGGHGPMFDLANDEISHALVREFYESGKVVSAVCHGPAALVNVKLSD-GKYLVAGQEVTGLSNAEEEIMQF----TKDMPFLLETKLRENGGIYQKADSPFGDKVITSGKLVTGQNPPSAGMIGKSLIK---------- +---PKLLIILTSQ-DILPTRDMKTGWYLPELVHPYNMLVP-HVDVVIASPKGGEAPIDPYSVEETKDAACQAFLRDNEPL----WKNTTKLESGRSSEFAGIFFVGGHGPMFDLAVDSISQELIREFYEAGKIVSAVCHGPAALVNVKLSD-GTYMVQGHAITGFSNAEEDAYQF----TDAMPFLLEDELKKHGGNYEKADQPFGIRVVVSGNLVTGQNPPSAGVIGGSLVE---------- +---PKLLVVLTSQ-DNLPTREFKTGWYLPEFVHPYNALAP-HVDLVVASPKGGVAPLDPYSVEESKDAECQRFLKENKDL----WEKTEKLSTGRSSEFVGVFYVGGHGPMFDLAVDQVSHLVIREFYEAGKIVSAVCHGPGALVNVKLSN-GEYLVKDSEVTGFSNAEEDAYNF----TDAMPFLLETELKNHGGKYVKADQPFGVKVVVSGRLVTGQNPPSAGVIGGVLLE---------- +---AKLLVVLTSQ-DILPTRETKTGWYLPELVHPYNILKS-HVEMVFASPKGGEAPIDPYSIEDSKTEACTRFLKENEAV----WKDTKRLETDRIDEFVGIFFVGGHGPMFDLAADSTSHLLIQKFYESGKIVSAVCHGPAALVNVKLSD-GTYLVKDQRVTGFSNAEEDVYNF----TDAMPFLLEDELKSHGGMYEKADQPFGAKVVISGNLVTGQNPPSAAVIGESLLD---------- +---PAVLMVISSH---------EPGWYLPELAHPFEILEP-SCRITIASYLGSNAPPDPKSVDVFKNEICARFYETKQEL----WKNSGKLEDGRADEFDVICFIGGYGPMFDVIDSKTAEEVILDFYHQNKLLTGVCHGSAAYAHVKNPS-NKFILDGHKIVGVSNKECELLFT----GIVEPWSVETELDKTGGKYEKAQNPFEGHVVVSKTFITGQNPASGLELGKAIYE---------- +---PKVLMVLTSN---------EHGWYLPELVYPYEILAP-YTEITVASHLGGESPLDQSSVAAFKDEMCARFVREKEGI----WKNTPKLEDPRAKEFDVLFYVGGYGPTFDVIDSEATIAFVDEFYRSKKIICGICHGAAVFAHRTIPG-TKSILEGHRVTGISDREVGILAS----SIEEPFSVEGELVKAGAKFEKAVEPFGGHVVVSSVFVTGQNPASGIGIGKAIYQ---------- +---FRVLMVLSSA-AKFTTTGAPTGWYLPEFAHPYKVLSE-IADITVVSPKGGFSQVDPGSVKNTATSLSHSFLKDNESV----WSNTGKISDGRGKEFDVICHPGGHAPLFDLAEDNDLKTLISEVYEAGKIVAAICHGVIVLKDVKLSN-GQYLVADAPVTGFSNEEEDKVGL----TDACPVLVETELVKMGGRFEKSDAPFKAHVTVA-RLITGQNPASAPGFAEAIKQ---------- +---PKVLFVLTSH-DQMGNSGKPTGWYLPEFAHPYDILAP-HAQITIASVLGGASPLDPASIDAAKD-ISVNFLKTQESL----WKNTAPLADGKAAEFDAVFYVGGHGPMFDLAHNTKSHQIISEFHSQNRIIAAVCHGPAALAYAKLPS-GKYFLEDTAVTGFSNTEEQNYGV----LDAMPFELETALNESNGKFEKAKDDYAPNVVVA-KIITGQNPASASGVGEAILA---------- +---PKVLVILTSV-DTIPKSGKTIGWYLPELAHPWEVLRN-RAELTYASPKGGVAPLDPISVDLFSSPVCKDFLDNHKAI----WENTQKLSTGRASEFDAVFYPGGHGPMFDLAFDEDSIALIKDFDAQGKVISAVCHGPAAFVNAKDAA-GEPLLKGKTVTAFTNEGEDMFKY----TEEMNFSLEDKLNESGGKFVKSEGPMGEKVVVD-RIITGQNPASSKGVGEEIAK---------- +--------MTTSV-DKMGD--KPNGTYLIELAIPFNEFAKKQYQVDILSPKGGEIPIYHSGD----TEIVKSIIKSDLFSN--KTKNSLKPEDINPEEYLAVFIPGGYGQFWDTHKNKEVQQIIAKIYESNGVIGTVGHGTATLIDVKLKS-GAYLVSNKTMTSFPSWNEKNIMF----GALLPYDMEIELQKRGADLKIYNEKKVNYEVVDSRLITASFSTSGKFVAEEVLK---------- +---KKILFITTNV-NEMKN--EPNGTYLIELAIPFNKFSQKKFEIDIVSPKGGEIPIYHSGD----TSLVKAVIKSELFQN--KTKNSLKPTEINPKEYLGIIIPGGYGQFWDTHKDVDILRVISEIYDNGGIIGTIGHGTATLIDVKLNS-GEYLVKNKTMTSFPTWNEKNIMF----GKLLPYDMETELLKKGANLKVYNERKINYEIVDSRLITASFANSGKFVADEVLN---------- +----KILVIAADE-RYLPMLF-STGNHPVETLLPMYHLHQAGFGFDIATVSGMMTKFEFWAMPHQ--EKIVPFFGL--YQA--QFRSPKKLSEGADSEYAGVFIPGGHGALIGLPESEDVARALRWAMGSDRFVISICHGPAAFLSLRG----DNPLSGYAICVFPDAADKQTPM----PGSLTWFFGEELKAMGMTLVN--DDIKGSVYKDRKVLTGDSPFAANALGQLAAK---------- +----KVLVIAADE-RYLPTLF-STGNHPVETLLPMYHLHAAGFDFDIATLSGQMAKFEYWAMPRE--QKIMPFFEC--YLP--QFRQPLALSDGADSDYAAVFIPGGHGALIGLPESEAVAETLRWVLRHDRFVISLCHGPAAFLALRH----ENPLNGYAICAFPDAADKQTPM----PGHLTWYFGEALKAMGLEIVN--SDIKGRVHQDRKVLTGDSPFAANALGQLAAK---------- +----KILLIGADE-RYLPTLF-STGNHPVETLLPMYHLHQAGFEFEVATVSGLMVKFEHWAMPNE--EAIVGLYNH--YLP--QFMRPRKLQDTPDSEYAGVFIPGGHGALIGLPSSEAVAETLRWALANDRYVISLCHGPAAFLALSH----ANPLQGYAICAFPDAADKQTPM----PGQLTWFFGEQLQKMGLTLMN--QDITGMVHKDRKVLTGDSPFAANALGKLAAE---------- +----KITGHLRDE-RYLPLLF-STGNHPIETLLPLYHLYQAGFQFDVATLSGQMVKFEHWAMPQQ--EVVVGFYNH--CLA--LFRSPLTLSDP-HSDYAGVFIPGGTVRLIGLPESEAVAEAIRWTLANDRHLISLCHGPAAFLALGK----ENPLNGYAICAFPDSADKQTPM----PGHLTWYFGEKLQAMGLTLVN--SDIKGTVHKDRRVLTGDSPFAANALGKLAAE---------- +----KILVICADE-RYLPLLF-STGNHPIETLLPLYHLYQAGFQFDVATLSGQMVKFEHWAMPQQ--EVVVGFYNH--CLA--LFRSPLTLSDP-HSDYAGVFIPGGHGALIGLPESEAVAEAIRWTLANDRHLISLCHGPAAFLALGK----ENPLNGYAICAFPDSADKQTPM----PGHLTWYFGEKLQAMGLTLVN--SDIKGTVHKDRRVLTGDSPFAANALGKLAAE---------- +----RILMIGADE-RYLLTFF-STGNHPVETLLPMYHLDAAGFAFDIATVSGNPVKFEFWAMPGE--QAVAGFFDK--YHG--QFQQPQRLAD---DTYAAIFIPGGHGALIGIPESAEVGEVLKWAAAHERFVISLCHGPAGFLAVGE----SDLYRGYKICAFPDALDAKTPM----PGHLTWKFGERLKSLGFEIVN--DDISGAVHRDRTLITGDSPLAGNNLGKLAAE---------- +----KILVIAADE-RYLPTLF-STGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHK--EKVMPFFEQ--HKS--LFRNPKKLADNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRH----DNPLNGYSICAFPDAADKQTPM----PGHLTWYFGEELKKMGMNIIN--DDITGRVHKDRKVLTGDSPFAANALGKLAAQ---------- +----KILVIAADE-RYLPTLF-STGNHPIETLLPLYHLNAAGFEFEVATISGLMTKFEYWAMPHK--EKVMPFFEQ--HKS--LFHNPKKLADNADSEYAAIFVPGGHGALIGLPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRH----DNPLNGYSICAFPDAADKQTPM----PGHLTWYFGDELKKMGMNIIN--DDITGRVHKDRKLLTGDSPFAANALGKLAAQ---------- +---KKILAVMVDE-RYLPVLF-STGNHPIETLVPLMHLSEAGYEIEIATPSGLMGKFEYWAFPKE--DAVKDAFET--LLP--KIRNPKNLADGADSEYAAIFIPGGHGAMISLQDDENVGAVLRWALDVDRYVITLCHGPAALLAA-GEN--SSPFDGYSIAVFPDSLDEGAVL----PGKLTWALGEALRAQGITLVN--DDMTGAVHADRKLLTGDSPLAANALGRLAVE---------- +----KILVVASDE-RYLSMLF-STGNHPIETLLPMIHLNAAGFDFDIATISGLMTKFEYWAMPWQ--ERVITFFEK--YKN--KFISPLQLKK--DEEYAAIFIPGGHGALIGLPESEELAVLLRCAMKKNMFILSICHGPAAFLSTRD----KNPLQGYSICAFPDNLDRETPM----PGNLKWFFGEELEKSGIKIIN--RDIDGAVFKDRRVITGDSPLAANALGKLAAL---------- +---YKVLMVASDE-RYVQMLF-STGNHPVETLLPMLHIHHAGFEIDVATLSGNSVKLEMWAMPNE--KNVMDIYEK--YLP--KLENSLKLSDAEDSPYLAVFFPGGHGALVNLPESRDVREVLKWAMEKDRKIVTLCHGPAALLAG-S----KFLFDGYKMTVFPDSLDEGAQM----PGKLKWLLADKLEKLGVKIVN--TGITGEVCKDRNVLTGDSPLAANNLGILTAD---------- +---RKILVVASDE-RYVQMFF-STGNHPVETLLPMMHLAHAGFDLEVATLSGNSVKIEMWAMPED--KPVMDFYHE--ILP--KFEQPHKLADAEDSVYEGVFFPGGHAALVNLPESSDVNQVLNWAMTEKRDIITLCHGPAALLAG-A----EFLFKDFEMVVFPDALDEGAQM----PGKLKWLLAERLEELGATVLN--DEMSGQVHKDRNLLTGDSPLAANALGILAAD---------- +---WKILLIGADE-RYLLTLF-STGNHPVETLLPMYHLDKAGFAFEVATLSGNPVKFEWWAMPME--EAVVGLYGK--YQG--QFRQPAKLADAPDSDYLGVFIPGGHGALMGLPESAEVKALLEWAMAHERFIITLCHGPAALLAVAN----PHTFAGYQICAFPDALDEQTPM----PGRLTWKFGERLKGMGFEIVN--SGISGEVCRDRNLLTGDSPLAGNPLGKLAAT---------- +---HKVLMIGTDE-RYIEMLF-STGNHPVEMLLPMLHMHYAGFEIDVATLSGNPVKLEIWAMPEE--KAVMDLYNQ--YLP--KLVNPKKLEDAEDSPYIAVFIPGGHGVLAGVPHSKDVKKVLDWALNKDKHVITLCHGPASLLAA-GVG--DFPFKGYELCVFPDSLDEGAQM----PGKLQWLVGENLAKLGVKIMN--EGITGQVHKDRKLLTGDSPLASNNLGILAAD---------- +---KKVLVILSDE-RYLAMLF-STGNHPVETLLPMMHLAAAGFSFDIATLSGRRAKFEQWAMPLG--DAVMAFYEE--VLP--QMEEPQKLEEAADVPYAAVFIPGGHGVLNAIPESREVHDVLHWAFANEVFIISLCHGPASLLAA-N----GFPFVGYELCVFPDSLDEGAIM----PGRLKKLVGKNLAALGVKILN--SDITGKVHRDRTLLTGDSPLASNALGKLAAE---------- +---HKILMVASDE-RYLEMLF-STGNHPVETMLPMLHIHHAGFEIEVATLSGNSVKFEMWAMPTE--EAVMGLYET--YLP--KFKNPHKLADAEDSPYLGVLIPGGHAALHGLPFSTDMKAVLNWAFANDKYIISLCHGPAAFLAA-SIG--DFPFNGYEICVFPDALDEGAVI----PGKLQWLLAERLESLGVKVLN--EGITGQVNKDRNVLTGDSPLASNNLGILAAE---------- +---HKVLMIATDE-RYIEMLF-STGNHPVEMLLPMLHMHHAGFEIDVATLSGNPVKLEIWAMPEE--KAVMDLYNQ--YLP--KLVNPKKLADSENLPYIAVFIPGGHGVLAGIPHSKEVKSVLNWALSQDKHIITLCHGPASLLAA-SVD--DYPFKGYEICVFPDALDEGAQM----PGKLQWLVAENLEKLGVKVLN--KGISGQVHKDRKLLTGDSPLASNALGILAAE---------- +---WKILVICADE-RYLRMMF-STGNHPVETLLPLYHLDKAGFGFDFATISGYPAKFELWAMPRQ--PEVMGLFAK--YAE--ALKAPMKLRDEGGSDYIGVFIPGGHGALIGLPESAEVKTLLEWVAAEDKFLISLCHGPAAFLAVGKD---STIYKGRKIVAFPDAMDAQTPM----PGHLTWKFGEELQAIGFEILN--EGISGQVHKDGKILTGDSPLAGNGLGKLAAT---------- +----KVLMVASDE-RYLLMFF-STGNHPVETLLPMYHLDRAGFDIDIATLSGNPVKLEMWAMPHE--AVVPATFQK--YLA--QFKKPLKLADGDDSPYLAVLIPGGHGALIGLPDSEDLKTLLKWAVAKDKFVISLCHGPAGLLAA-AVN--NYIFKGYKMCVFPDALDQGALM----PGELPWLLADRLEKLSVEVVN--KEMSGQCIQDRKLITGDSPLASNTLGKMAAQ---------- +---WKILMIGSQE-RYLMMFF-STGNHPVEMLLPMYHLDAAGFEIDVATISGDPVKFEWWAFPHE--EAVKSIYKK--YEK--QLKAPKKLADTAETPYLGVFIPGGHGVLNGVPFSRQVGDILHWAQANERFTISLCHGPASLLAT-AVD--KFAYEGYEMCVFPDTLDTGAII----PGPMAWLVGENLRKYNVKILN--TGITGQVHRDRHLLTGDSPLASNNLGKLAAT---------- +---WKILMIGTQE-RYLMMFF-STGNHPVEMLLPLYHLDAAGFEIDIATISGDPVKLEWWAFPHE--EAVKSIYKK--YEK--QLKTPKKLADTAESPYLGVFIPGGHGVLNGVPFSRQVGDILRWAQSNGRFTISLCHGPASLLAT-AVD--RFAYEGYEMCVFPDSLDAGAII----PGPMAWLVGEKLREYNVKIVN--TGITGQVHRDRNLLTGDSPLASNNLGKLAAE---------- +---YKVLLVGTDE-RYLQMYF-STGNHPIETLLPLMHLHHAGFEIEVATLSGNQVKFELWALPKE--QAVMDFYHE--LLP--KLEAPAKLADAKDSPYVAVFFPGGHGALLDLPESKEVKQVLQWAMANEKKIVTLCHGPAALLAA-ANE--DFLFASYEMTVFPDSLDEGAIL----PGQLKWLLGERLEKLGVKVIN--QDVTGQVHKDRNVLTGDSPAAANKLGILATQ---------- +---NKILMIASDE-RYLQMYF-STGNHPVETLLPMLHMDAAGFEIDIVTLSGNSVKLEMWAMPEK--ENVMKLYNK--YIE--KFENPVKLDRSEDSPYSGVFIPGGHGVMINLPESSEVKEVLKWAIKENKKIITLCHGPAALISG-N----EFLFKNYEMTVFPDSIDEGAQM----PGKLKWLLAEKLESLGAKIVN--EAISGQVHIDRNLITGDSPLAANQLGIVAVD---------- +---LKILMIGSDE-RYVQVLF-STGNHPVETLLPMMHMAAAGFDIDVATLSGNSIKLEMWAMPEE--EAVMDFYHD--YLP--KFENPLKLSEADNSPYVAVFFPGGHGALLNLPESEEVKDILNWAMTNDKKVVTLCHGPAALLAA-T----DFLFDGYEMTVFPDSLDEGAQM----PGLLKWRLQETLEENGVKVLN--EDITGQVHKDRNLLTGDSPLAANNLGILAAN---------- +---HKILMIATDE-RYLLMFF-STGNHPVEMLLPMYHLDKAGFAFDIATISGEPAKLELWAYPKD--AAVASIYEK--YKP--QLKSPLKLADGPDSAYVAVFIPGGHGALNGVPFSTDVKKALDWALRADKHIISLCHGPAALLSAKIGE--ENPFKGYKICSFPDAIDAKTPM----PGAMPWFIGERLRADGLEIVN--TDIKGTVHQDRKLITGDSPFASNNLGKAAAE---------- +---TKILAIFTEQ-KNMTMLF-STGNHPVEALVPMLHLKNAGFEFEIVTPTGKPVVFEMWAFPEK--EHVKAFYNK--YKS--NFEQPKSLDEDVTASYAAVFVPGGHGAMLGIPEDINVGKVLNWAHENDLFTVTLCHGPASLLATTLDG--RFLYQGYKMAVFPDSVDKMTPL----PGQMTWGLSEKIQSLGVNIVN--KKSDNTVCLDRKLITGASPLASDALGKLAAE---------- +---SKILVICTEQ-KNMMMLF-STGNHPVETLVPMLHLKNAGYDFEIATPTGKPVVFETWAFPGK--EQIKSLHDK--YAS--SFSQPKNLQVPDPECYAAVFIPGGHGAMLGIPEDENVQKILNWAHENELFTVTLCHGPAALLATTLGG--DFLYAGYNMAVFPHSVDKMTPL----PGQVPWALSEKLTALGARIAN--SKADDTVCLDRQLITGASPDAANELGKLAAR---------- +---KKVLVIFTEQ-KNMTMMF-STGNHPVEAILPMLHLKNAGFEFEIVTPTGKPVVLEMWAFPKK--EYVKAFYEE--YKQ--QFEAPGSLQHQNNDEYAAVFIPGGHGAMLGIPDDHNVDKVLRWADSNDLFTITLCHGPAALLATTLDE--PFLYEGYKLAVFPDSVDEMTPL----PGKMPSSVSGKLEGLGMTLMN--TKSDNTVCRDRLLLTGASPLAANELGKLAAK---------- +---NRVLMVCTEQ-RNMPMKF-STGNHPVEMGLPMLHLMNAGFEIDVVTPTGARVAIEEWAMPAD--ADIQKLFRD--FAG--AFQNPTSLAETDDTAYAAVFIPGGHGAMLGLPDNADLGKVLRWAQKTGLHTLAICHGPAALLAAKSD---GFLYDGYKMTVFPDAVDKQTPL----PGPMPWWVCERLNALGVETIN--KKADNSTHVDRRLVTGASPQAANDFGRLAAT---------- +----RVLVIGTDE-RYLRMLF-STGNHPVETLVPMYHLREAGFEFDIATVSGNGLMFEFWAMPDE--EAITGLHRD--LLA--RFVQPLKLSDG-GADYAAVFIPGGHGPLVGLPFSKDVAAVLRWALAKDRHIVSICHGPAALLACETKD--QFPFAGRKITAFPDDVDRMTPM----PGHLTWHFGQRLEALGVEIVN--SKPDDSTQADGKLLTGASPYAANELGKLAAK---------- +---RKILTIAVDE-RYLPTLF-STGNHPVETLVPLMHLRAAGYEIEVATLSGNMAKFEMWAMPTE--EAIKAGYEE--LLP--ALLKPRRLADGPDSDYAAVFVPGGHGAMGGIPDSPAVRDVLVWALENERPVVALCHGPAALCAAVDEG--ASHFAGYSLCAFPDSFDVGPLL----PGRLTWRLGERLKRQGLTIVN--DGASGQTHRDRLLLTGDSPLAANALGRLAVE---------- +----RILLIGTDE-RYLKMLF-STGNHPVETLVPMYHLHKAGFEFDIATVSGNPVKFEFWAMPKE--EAITGLHKA--YLD--AFQKPLKLADGPDSDYAAVFIPGGHGPLAGLPFSDEVGAVLRWALENDRHIISICHGPAALLACTPKV--PFPLAGYSITAFPDAADRMTPM----PGHLTWHFGEKLKALGVTILN--TEVDTSTHKDRKLLTGSSPFAANNLGKLAAE---------- +----KVLMIGTDE-RYILMMF-STGNHPVEMLLPMYHLDKAGFEFDVATLSGNPVKLEMWAMPGE--EAVKSIYAK--YLP--KLKAPQKLADADDSPYAAVFVPGGHGVLAGIPHSREVKRLLNAFLAKDRYIITLCHGPACLLAPAVEE--DYPFKGYEICVFPDALDTGALM----PGPLPWLVGENLQKLGVKILN--KGITGQVHRDRKLLTGDSPLASNNLGKLAAK---------- +----KFLAILTDE-RYLEMYF-STGNHPVETLLPMFYIDNAGFNIDIATLSGNPAKLECWAMPTE--ETVLKTLAK--FRE--QLKHPLNLNEGPDSPYVGVFIPGGHGVMAKIPESKAVSKVLNWALQNDKYIVSLCHGPAALLAT--AA--DFSFKGYKVCVFPDSLDTGAQM----PGQLKWLVAEKLKKLGAEIVN--DDMTGKVIKDRKLYTGDSPLASNNLGKLVAK---------- +---WKVLVIAADE-RYLMLMF-STGNHPVETLLPLHHMIEAGFDIEVATLSGNPAKLEYWAMPTE--EAVMGTYEK--LKA--QLQSPKKLSDGADSDYLSVFIPGGHAALIGLPDSEDVQKTLDWALGNERFIVTLCHGPAALLAASL----HSPLAGYEICVFPDALDEGAIL----PGRLPWLLAERLTEDGLKVVN--DTMSGQVLKDRNVLTGDSPLASNALGKLAVN---------- +---WKVLMIAAEE-RYVLLMF-STGNHPVEMLLPLHHLMEAGFDVDVATLSGYPAKLELWAMPTE--EAVLSTYNK--LKE--KLKQPKKLSDGPDSDYLSVFIPGGHAAVVGISESEDVQQTLDWALENERFIITLCHGPAALLSAGL----KSPLEGYSVCVFPDSLDEGAIL----PGRLKWLVADLLTKQGLKVVN--DDMTGKTLKDRKLLTGDSPLASNELGKLAVN---------- +---WKILLIGADE-RYLLTMF-STGNHPVETLLPMYHLDKAGFAFDVATLSGNPVKFEFWAMPSE--SEVKEFYAK--YRE--QFKKPLKLSDGDDSDYIGVFIPGGHGALIGLPESFDVKHVLQWAVAKDKFVISLCHGPAALLAAGLEE--SYVFNGYKICAFPDALDAKTPM----PGHLTWKFGEQLEALGVEIIN--EGISGATFRDRKLLTGDSPLAGNNLGKLAAD---------- +---WKILMIAADE-RYLLLMF-STGNHPVETLLPMYHLDKAGFEFDIATVSGNPVKFELWAFPNQ--DAVKSIYQK--YLG--RLKQPLKLSDGKDSDYIALFIPGGHGALIGLPESLDVKAALKWALDNDKHIVSLCHGPAALLASAVGE--DYPFKGYKICAFPDAIDRTTPM----PGALTWAFGERLQALGVEILN--KDITGKTYQDRKLITGDSPFAANNVGKAAAK---------- +---ARVLVVLTEE-RNMMMKF-STGNHPVEMALPMLHLINAGFELDLVTPTGAPAIIEQWAMPNN--KSVAKLFAK--YDD--ALAKPNSLIDIDNSPYVGVFIPGGHGAMLGLPSDPNLGKILRWAQKKNIHIITLCHGPGTLMSAKID---EFIFNGYEIALFPDAVDKQTPL----PGQMPFELGEKLQELGMHIIN--KKADDTCHIDRNLITGASPYASNKLGRLAAE---------- +---WKILLIATQE-RYLKMFF-STGNHPVEMLLPLLHLDAAGFEIDIATISGNPVKLEMWAFPQE--EAVKGIYEK--YKE--KIRSPLNLHDTKDTPYIGTFIPGGHGAMNDVPFSETVGKILRWGDENQRFLITLCHGPAGMLAADVGK--KFIYDGYEIVVFPDSLDTNAVI----PSKMPWYVGERLRKLGIKLRN--NSITGETHRDRYVITGDSPLASNNLGKLAAN---------- +---FKVLMVATDE-RYLQMFF-STGNHPVETLLPMLHIHKAGFEIDVSTLSGNHAKFEMWAMPGE--QAIAEIYAE--YLP--KLDKPARFADAPDSPYIAVLIPGGHGAFNKLPESRDMQRLLDWALENDKFIITLCHGPAALAAA-SVG--EFPFKGYELCVFPDALDEGALM----PGKLPWLLAKRLEELGMVVKNSKTSIDGSVHKDRRLLTGDSPLAGNALGILAAD---------- +---YKVLMIATDE-RYVKMLF-STGNHPVETLLPMLHIHEAGFEIEVATLSGNPVKFEMWAMPKE--QAVAGIFET--YLP--KLQKPHKLADDEDSPYIAVFVPGGHGVLNAIPESSEVARVLNSMLDKNRYIITLCHGPAALVS---LA--AFPLKGYELCVFPDSLDEGAIM----PGRLPWLVAERLQALGMKVMN--KDITGKVCQDRQLLTGDSPLAANNLGILAAD---------- +---WKILVLATDE-RYLLMMF-STGNHPVETLLPLHHVLGAGFGVEIATLTGNPAKFEWWAYPGE--EAVRSTRDA--LLP--QWRKPKSLADGPDSDYLGVFVPGGHGALSGLPFSTDVRDTLEWATGAGRLVVSLCHGPAAFLSTRIGR--RSLFEGYEMCVFPDALDAGAVL----PGPMPWMLGRALQDDGVRVVN--DDMSGRCTTDRDVITGDSPLAANELGRLTAT---------- +---WKILMLCTDE-RYLQMFF-STGNHPVETLLPMYHLDKAGFSFDIATLSGNPVKFEYWAMPTE--IEVTGLFSK--YHQ--HFKSPLKLADGDNSDYLGIFIPGGHGALIGLPASIEVKNLLEWAIAHDKFIISLCHGPAAFLSVER----SDLFAGYKICAFPDTLDAQTPM----PGHLTWKFGEQLKSIGFEIVN--TDISGATCQDRKMLTGDSPLAGNALGQLAAK---------- +---WKVLLIATQE-RYLRMFF-STGNHPVEMLLPMVHIDAAGFDIDVATLSGDPVKLEMWAFPNQ--TAVKDIYNK--YKE--KLRSPLNLQKTKDTPYLGVFVPGGHGVLNGIPFSETVGNILRWAHESDRYLITLCHGPACMLAADVGK--KYIYEGYNIDVFPDSLDQGAII----PGKMEWLVGERLRALGVTPIN--KQITGETHQDRLVLTGDSPLASNNLGKLAAK---------- +---WKVLVIATEE-RYVLLMF-STGNHPVETLLPLHHLMETGFEVDVATVTGYPVKLELWAMPRE--EAVLATYEA--LKP--KFKQPKKLSEGPDSDYLAVFIPGGHGAMVGLPDSPAVGEALEWALTNDRFIITLCHGPAALLAAAA----ESPFKGYSVCVFPDALDSGAIL----PGELTWLVAEQLRKRGVTILN--DDMTGKTYQDRKLITGDSPLAANELGRIAAD---------- +---WKVLMIAAGE-RYVLLMF-STGNHPVEMLLPIHHLMEAGFGVDVATLEGYPAKLELWAMPHE--EAVMGAYEA--LKP--KLKEPLRLSDGDDSDYIAVFIPGGHGAVVGLPTSVSVGRTLDWALANGKFVITLCHGPAALLAATL----ESPFKGYSVCVFPDALDEGPLL----PGRLPWLVADLLGKQGLNVVN--DDMTGRTIRDRQLLTGDSPLASHSLGLLAAD---------- +---WKVLMIATDE-RYLLMMF-STGNHPVEMLLPLHHLMAAGFDVDVATITGNPVKLELWAMPGK--DAVQQTYAA--LKP--QLKEPLNLREGPDSDYLAVFIPGGHGVEVGIPFSPEVGQVLDWALANDKFIITLCHGPASLLAAAI----DSPFKGYSICVFPDALDKGPKL----PGGLRLFIAEALEDQGLEVVN--DQMTGQVHQDRRLLTGDSPLASNNLGLLAAD---------- +---WKVLMIGTDE-RYLLTFF-STGNHPVEMLLPLHHLIEAGFDVDVATLSGNPVKLELWAMPGE--EAVRKTYEA--VKP--KLKQPLKLSEGPDSDYLAVFIPGGHGAVIGIGDSEDVTATLDWALANDKFVITLCHGPAGLLSAAK----KSPFDGYSLCVFPDALDTGALL----PGPLRWLVADLLRQQGLTVLN--SGITGRTHQDRKLLTGDSPLASHALGLMAAD---------- +---WKVLLVAADE-RYLLTFF-STGNHPVETLLPMYHLDRAGFEFDIATLSGNPTKFEWWAFPSE--AEIKSLYAK--YEQ--KFQQPLKLADDKDANYIAVFIPGGHGALMGLPFSADMKATLQWAMQNDRFIITLCHGPAALLSAGVDE--GDLFRGYRICAFPDSMDKQTPM----PGPLRWFFGEKLAAMGVEIVN--TKIDGSTFRDRKLLTGDSPFAGNNLGKLAAR---------- +---WKILLIGSQE-RYLKMFF-STGNHPVEMLLPLLHLDLAGFDVDIATPSGDPVKFEVWAFPSE--DAVKGIYEK--YAE--KLRSPLSLEKDKATPYLGVFIPGGHGVLNDIPFSKTVGDVLRWADANQRFLITLCHGPACLLAADVEK--KYIYDGYKIVCFPDSLDKGAII----PGKMPWLVGEHVRKLGVEIIN--DAITGQVHRDRYLLTGDSPLASNNLGKLAAE---------- +---WKILVIGTQE-RYLQMFF-STGNHPVEMLVPMLHLHRAGFELDVATLSGEPVKLEMWAFPKE--ESVKSFYEE--YKQ--KLRNPLTLSENDSTPYKAVFVPGGHGALNGLPQSKVVGDILRWADKNKRYLITLCHGPACMLAANIGK--KFIYDGYKIDVFPDSLDNGAII----PGKMKWLVGEELQRLGVQILN--EKITGETHQDRYVLTGDSPLASNNLGKLAAD---------- +---WRILTIATQE-RYLQMFF-STGNHPVETLLPILHLDAAGFEVDIATVSGDPVKLEMWAFPKE--EAIKKIFEK--YKP--KLRQPLNLDRTKDTPYIGIFIPGGHGALNDIPSSPTVGKILRWADANRRYVISLCHGPAALLAADVDK--KFIYSGYKIDVFPDALDSGAII----PGKMTWLVGEELRKLGVIPIN--KEITGETHRDRYLLTGDSPLASNNLGKLAVR---------- +----KVLMIATDE-RYIQMFF-STGNHPVEMLLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQ--QVVLDTFQK--YAD--KLKNPLKLADGENSPYTAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVDE--NYIFKDYQICVFPDSLDKGAIM----PGALPWLVGENLEKLGVKILN--TGITGQCHRDRKLLTGDSPLASNNLGKLAAE---------- +---WKILMIGTEE-RYMMMFF-STGNHPVEMLLPLHHMHAAGFDVDIATLGGNPVKLELWAFPSD--PTIAETYEE--FKP--KLKKPLSLQDGEDSDYLAVFIPGGHGAMNDLPHSPVMQKVLDWALDDDRLIIALCHGPAALAAS-GLN--ASRFDGYSICVFPDALDRGARI----PGELEWYVGEALEKQGFTILN--QDMTGAVHRDRNLLTGDSPLASNQLGIVSAE---------- +---WKILLIATEE-RYLLTFF-STGNHPLELLLPLLHFAAAGFEVDVATLSGNPAKFELWALPNE--EAVKAGFEK--FLP--KFRQPLKLSDGPDSDYIALFVPGGHGVINGIPESELVGKTLDWALTNDKHIVTLCHGPVFLSSLLAVG--DYPLRGYQITVFPDALDEGAVL----PGRLVRLVAKELEELGLVVLN--TGITGQVHQDRKLLTGDSPLASNNLGKLAVP---------- +---WKILTIATEE-RYLLCMF-STGNHPVETLLPLIHLMKAGFEVEIATVAGYPAKLEWWAMPGE--EAVRQAYES--LKP--KFKEPKKLSDGDDSDYLAVFIPGGHGALLGLPDAEAVAHTLDWALDRDKYIITLCHGPAALLAVGR----QSPFEGYSMCVFPDALDEGAVI----PGHLPWLLAEALQAQGITVLN--DDMTGRVHRDRTLLSGDSPLAANNLGLLAAD---------- +---WKILMIATEE-RYMLMMF-STGNHPVEMLLPLHHLKAAGFGIDVATVSGNPAKLELWAMPRQ--EAVLNTYAE--LSA--QLKKPQKLSRGPDSDYLAVFIPGGHGVLLGIPDSEEVRTVLEWALEYDKYIITLCHGPGALLAA-GLD--ESPFQGYSLCVFPDSLDTGVII----PGQMPWLVGENLRKQGVTILN--TGITGQTHADRKLLTGDSPLASNNLGLLAAE---------- +---WKVLMIASQE-RYLLMFF-STGNHPVEMLLPMYHLDLAGFEIDIATPSGDPVKLEMWAFPHE--PAVKATYEK--YRS--QLKQPKKLTE-DGGNYLGVFIPGGHGVLNDIPFSEEVKKTLHWAHDNDRYVISLCHGPAGLLAA-GIG--DFLYRGYEMCVFPDALDTGAVI----PGPMPWLVGERLRELGVKIVN--ADITGKVHKDRRLLTGDSPLASNNLGKLAAE---------- +---WKILLIATQE-RYLKMFF-STGNHPVEMLLPMVHLDAAGFDIDIATLSGDPVKFEVWAFPKE--EAVNSIYKK--YED--KIRSPINLQDSSETPYLGVFIPGGHGVLNDVPFSKLVGDVIRWAHDSQRYYITLCHGPASMLAANVGK--NFIYVVYEIVVFPDSLDTGAII----PGKMPWLVGEELKKLGVKPLN--AGITGQVHRDRFLLTGDSPLASNALGKLAAN---------- +---WKVLLIGTQE-RYLPMFF-STGNHPVELLLPLLHLDAAGFDVDVATPSGGPVKLEVWAFPSR--EAVTQIYKK--YEE--KLRAPLSLEADASTPYLAVFVPGGHGVLNDIPRSRLVGDVLRWAHAQDRYVVTLCHGPAALLAAEVGA--RFLYDGYEVVAFPDALDQGTII----PGKMQWLVGEALRKRGVKTLN--EGITGRVHRDRLLLTGDSPLASNALGKLAAE---------- +---WKVLMIATEE-RYVLCMF-STGNHPVETLLPLHHLMQTGFDVDVATICGYPVKLELWAMPHE--QAVLSTYEA--LKP--KLKQPLKLSEHASSDYLAVFIPGGHGAVVGLPGSDAVGQTLNWALDHGRFIVTLCHGPAALLAAGL----QSPFTGYSVCVFPDSLDEGAIL----PGRLQWLVADLLAKQGLTVVN--DEMAGTVHQDRRLLTGDSPLASDALGKLAAN---------- +---KKILVVASDE-RYVLTFF-STGNHPVETLLPMMHLAHAGFEIEVATLSGNPVKLEQWAMPTE--KAVMGYYDS--ILP--KFKEPKRLSDKPESCYVGAFFPGGHAALVGLPFSLDVKRVLLWAMKENKVLISLCHGPAAFLAA-AID--DYLFKGFDMEVFPDALDEGAQM----PGCLRWLLAASLEKLGVHLLN--SDITGAVHVDRNVITGDSPLAANKLGLVAAK---------- +----KILVIAADE-RYLPVLF-STGNHPVETLLPMYHLHKAGFKFDIATLSGEMVKFEHWAMPVD--KAITGLFDD--YLA--GFRQPLKLSDA-DSDYAGVFIPGGHGALIGLPESEDVAAAIRWTLDQDKYLISLCHGPAAFLSVSK----DNPLKGYSVCAFPDSADKQTPM----PGHLSWFFGERLKEMGLTLVN--DDISGAVHQDRNVLTGDSPFAANALGKLAAS---------- +----KILVLCADE-RYLPLLF-STGNHPVETLLPMYHLHQAGFGIDIATLSGQMAKFEHWAMPGE--EAVLQFYQR--YQS--AFRSPLRLADP-HSDYAAVFIPGGHGALIGLPESKEVATLLRWTLENDRYLISLCHGPAAFLSLAG----DNPLAGYEICAFPDAIDKQTPM----PGHLTWYFGEKLRAMGLHIIN--EDIKGTVHRDRNVITGDSPYAANALGKLAAE---------- +---WKVLMIAADE-RYLPTLF-STGNHPVETLLPMYHLDKAGFGIDVATLSSNPAKFEWWAFPNE--KEIGGLYER--YAS--CFRQPLPLDEDADSDYAAVFIPGGHGALIGLPQSRAVKSVLHWAMAQQRHIITLCHGPAALLAAGVDE--GSLFRGYRICAFPDAMDRQTPM----PGQLPWFFGERLAQRGVQIVN--DGIDGSVLQDRLLLTGDSPLAGNALGKLAAR---------- +----KILVIATDE-RYLAMLF-STGNHPVETLLPMYHLHQAGFAFDIATPSGLMVKFEHWAMPCE--AAIQGLYQH--YLP--QFRRPRRLREAGEQDYAGVFIPGGHGALIGLPFDADVAETIRWTMREDRYLIAICHGPAAFLSLAL----ENPLRGYALCAFPDSADRQTPM----PGELPWFFGERLQAMGMTLVN--TAISGQVHQDRKLLSGDSPFAANALGQLAAR---------- +----KILMVCTQE-QYMTMKF-DTGNHPVEMFVPLLHFKKAGFEVDIFTPTGESVKIEQWAMPNE--EKVKEIYSS--YQS--KREAPQSIEDADSEDYAAIFIPGGHGAMLGLPENKYLGELLRWAHESDLYTLVICHGPAALLSANLERPGDFIYKDYDIVAFPDVMDKQLPL----PGEMPWYFNEKLEALGVTITN--KLASGHTHQDRKLISGDGPLAANDFGKLATE---------- +---KKVLVVCTEE-KYMTMKF-STGNHPVETLVPMLHLDAAGFEAEIFTPTGAPAVLEMWAMPSE--EAVKGIFEK--YKT--KFETPKSLKEASETEYVAVFLPGGHGAMLGLPTNDDLKKIIHWAYQHEKFVLAICHGPAALLAAAHNE--NFPYKDYKIKSFPDIIDTQTPV----PGEMPWFYGEKLKALGIEILN--EDISGACYTDRKLVTGDSPLAANNFGKMSAE---------- +---KKILVVCTEE-RYMEMKF-STGNHPVETLVPLLHLEAAGFEADIYTATGKPVALEMWAMPSE--KAVKEILVR--YED--QLDKPKSLRKETSVEYVAVFIPGGHGAMLGLPENEDLKKIINWSIDKDIFMLAICHGPAALLAASVKE--DFPYKGYQINSFPDEIDTKTPV----PGEMPWFYGAKLEALGIEILN--TDISGACHVDRKLITGDSPLAANAFGKVSAK---------- +---VKILIIGTEE-DQLVMSF-LTGNHPVELFVPMLHWKKAGFKFDFATPTGKEMKLEHWAMPNQ--KAVMEIYED--CKD--QIKNPLSLKN-DTIDYAAVFIPGGHGAVIDLPKSKEVQEVLFWAKEKDKFIISICHGPAAFLAAGINE--NFIFNGYYMAAFPDSMDKLLPL----PGKMPWYFGKELQELGMSIVN--KIANGQVYQDRKLITGDSPLAANKLGKLSTL---------- +---SRIMMICTEE-KNLTMNF-STGNHPVEMLVPMLHLQNAGFHIDVFTPTGKSAKIEGWAMPTE--KNVMSLYAQ--YEE--QYNNPKSLSENGNSEYTAIFIPGGHGAMNGLPENQDLKKLVHWSFQKDLHMLAICHGPAALLSANLNQ--EFLYSGYSMAVFPDSMDKQTPM----PGQLTYQFGRKLSELGVNIVN--KKADKTCHQDRKLITGASPQAANDFGILSAT---------- +---NRVLMVCTEQ-RNMTMKF-STGNHPVEMGLPMLHLMNAGFEIDIVTPTGAPVAIEMWAMPSD--ADIQKLYRD--FEG--AFKNPGSLEDTDDGPYAAVFIPGGHGAMLGLPDNADLGEVLHWAHNTSLHTLALCHGPAALLAAKSD---GFLYDGYKITVFPDSVDKQTPL----PGPMPWWVCEKLSAQGVEIIN--EKADNSAHVDRRLVTGASPQAANNFGRLAAT---------- +---KKVLVLCTEE-RYFEML-FSTGNNVQETMVPLMHLVNGGFNFDVVTSTGKPAILEEWSVPIKD-KAVLAFRE--EHQT--KFDTPLSLKAKGDSDYIALFLPGGHGSMVGLPDDKNVGKLLRWIETSDRYLVAVCHGPAAMIAKDQSN-APNPYRGYKMVAFPDKFDKQSPL----PGQLTWFQCEALEKEGIEVIN--DKITGATHVDRKLISGDSPKACDELGKITVA---------- +---KKILVLCTEE-RYMIMKF-STGNHPVETLVPILHFEQAGFEVDFYTPTGAPVKFEMWAMPYE--ENIGNILDK--YNT--QFSNPHNLRHKGYVDYVAVFIPGGHGAMLGLPENNDVKELIKWAVTEDKYLLAICHGPAALLSAADC---EFPFKGHKINSFPDEMDKTLPQ----PGEMPWFYGEKLKQLGVEILN--KKIAGDCHVDRKLITADSPLAADKFGKLCAD---------- +---AKVLMVCTEE-RYMTMKF-STGNHPVEMLVPLLHLEKAGFQIEVCTPTGAPVKIEMWAMPEK--DAVKGALQR--YQS--QFDKPLSLKDNDRADIVGVFIPGGHGAMLGLPDNDDLQTLIRWVNANDKTMLAICHGPAALLAENRGS--DFAYRGYKMAVFPDSLDKLTPL----PGPMPWYFGDRLREQGVEIIN--KKANGTCCTDRKLITGDSPDAANEFGKLAAR---------- +----KILMVCTEE-QYMTMKF-DTGNHPVEMMLPLLHFKKAGFDVDVFTPTGKSVQVEQWAMPEE--DDVKQIYAE--YQL--KLENPKSITDADSDDYAAIFVPGGHGAMLGLPEDKSLGKLLRWGYDNDLFVLAICHGPAALLAANLGDF-DFIFKGYKMVAFPTVMDKQMPL----PGTMPWYFGDKLEELGVTIDN--KLASGQTHQDRKLISGDGPLAANEFGKLSAN---------- +----KVLMICTEQ-KNMTMKF-STGNHPVEILLPVLHLKNAGFDVDVVTPNGKPVVIEQWAMPED--EHIKAIYAE--FKK--IFENPGNLSDNESSDYAAIFIPGGHGAMLGLPENKDVNKLINWSHKNDMFTLAICHGPAALLAAGLDS--TYVFKGYKIASFPDAVDEQGLT----PGHMPYKYGEKLNNLGVTIIN--EEADNTVHKDRKLITGASPLAANDFGKLAAT---------- +---WKVLVIATEE-RYLEMLF-STGNHPVETALPLKHLLDAGFGVDVATLGGNPVKFEWWAMADD--DAVVETMNA--LED--KFRHPLNLTEGADSDYLGVFIPGGHGALNGLPSSTVVRDTLDWALDNERFVVTLCHGPAALLASGVGR--ESRFKGYEVAVFPDSLDKGPKV----PGEMPFLFGEELKKQGLTLVN--DDMAGTVHRDGLLLSGDSPLAAHSLGKLAAD---------- +---WKVLMIATDE-RYILMMF-STGNHPVEMLLPMHHMDKAGFEIDIATLSGNPAKLELWAMPSD--EAVQSTYRK--YLP--KLKTPLKLSDGADSPYIAVFIPGGHGVLAGIPHSKDVKRTLRWALDQDRHIITLCHGPACLLSA-AVD--DYPFKDYELCVFPDALDTGPLM----PGPLPWLVAQSLEKLGARVLN--KDMTGRCHQDRKLITGDSPLASNGIGKLAAA---------- +---WKVLMIATDE-RYVLMMF-STGNHPWEMLLPMYHMAKAGFDIEIATLSGNPAKLELWAFPTE--KEVQSIYQQ--YLA--QLKSPQKLSDGDDSDYIAVFIPGGHGALVGIPHSKEVKSVLKWAMANDKYVITLCHGPASLLSA-AVG--NYMYKGYKICVFPDSIDRQ-PM----PGQLTWHIGEELKKLGVEILN--GDITGMTHQDRKLITGDSPLASNNLGKAAAK---------- +---WKVLVIAAHE-RYMRMFF-STGNHPVETLLPLHHMAQAGYGIDVATLTGGPGKLEWWAYPSQ--EAVASTWEA--AQE--SFKTPRALAD---DDYAAIFIPGGHGAMTGLPDSRELRSALDFFMEQDRLIITLCHGPAALLAAGIDR--KNPFAGRRITAFPDSLDLGAIL----PGQMPWNLGEQLTAAGFEIVN--DDMSGATTRDGNLLTGDSPLAANQLGKESAL---------- +---WKVLVIAADE-RYMLMFF-STGNHPVETLLPLHHILEAGYRVDVATLSGGPGKFEWWAYPRE--QAVASAWEA--TRE--AFKAPHRLST---EDYAAVFIPGGHAAMNGLPHSADLRDALDFFLREDRLIITLCHGPAALLAAGVGR--GNPLAGYRITVFPDRLDFGALL----PGEMPWRLGEKLREAGLEIAN--EDMTGATLRDRNLLTGDSPLAAHRLGKESAL---------- +---WKVLVIATDE-RYMLMFF-STGNHPVETLLPLHHIAEAGYGIDIATVSGEPGKFEWWAYPKD--EAVGSAWKA--TKE--QFKDPKRLAE---DDYAAIFIPGGHGAMNGIPDSAVLGEALDYFLDNDRLIITLCHGPAGLLASGVGR--ENPFSGYRIVAFPDSLDQGAIL----PGKMPWALGEALEKAGIVVEN--TEMTGATTRDRNLLTGDSPLAANQLGKDSVQ---------- +---WKILVIATEE-RYMPMFF-STGNHPVETLLPLYHMHKAGFGVDVATISGSPAKFEWWAFPSK--DAVNDAWDA--TKS--AFKQPKKLSD---DDYAAVFIPGGHGAMNGVPSDSSVGEALRYFLNNDRLIITLCHGPAALLAAGNGS--ENPFAGYSVVAFPDALDFGAIL----PGEMPWKLGEKLQEAGLTISN--EDMSGATTRDRNLLTGDSPLAANALGKESAL---------- +---KKALIIGSNH-ATLNADGDATGVAISEVTHPYYSFLDAGMLVDVASIDGGEIPVDPMSLKFFIIEHDERYLEDPTLQA--KMQNSLAIGNVDISQYDIIFIAGGWGAAYDLGYSPVLANKISEAYYHQPVIAGVCHGVLGLINAKDRD-GQLLIAGRRMTGVTDKQIKELGV-----AITPMHPETELKKAGAQFEAKTDFFATHVVIDDRFVTGQNQNSGLEAAHKVLM---------- +---KRALVITTSH-GVLSAEGAATGVFGSEMTHPYYNFLDAGMNVDIASIKGGEIPVDPQSFMYMVRPEDTRYLQDQVFQA--KVKNSLKIDDVDMSLYDVIFMSGGWGAAYDLGQSEALASQVTQAFYRVPVIGGVCHGVLGLINAKDRN-GKLLISGRKMTGVTDKQIKELDI-----DMTPLHPETELRKAGVQFESQTDFFATHVTVDDRFVTGQNQNSGHETAQNMMR---------- +---KRALIIATNQ-AVLSATGDATGVMASEMTHPYYRFLDAGMQVDLASIKGGKIPVDPQTINWLLKPEDDRFLADPAFLA--KVENSMRIDDVDFTQYDIIFMAGGFGAAYDLGYSPVLAEKISEAYYNEPVIGGVCHGVLGLINAKDRD-GKSLIAGRRMTGVTDKQIKELGI----IEITPQHPETELRKAGVIFESNTDFLATLVVVDDRFVTGQNQNSGRETAHRMLE---------- +---KRALIITTSH-AVLNATGDATGVFGSELTHPYYTFTDGGMSVDVASIQGAEIPIDPQSFNRPIIPEDKRYLKDSVFQA--KVKNSIPIADIDVSQYDIIFLSGGWGAAYDLGQSELLGKKISQAYYLSPVIGGVCHGVLGLINAKDNS-GQLLIAGRKMTGVTDKQIKELGI-----AVTPLHPETELRKAGVAFESNTDFFATHVVVDDRFVTGQNQNSGLETSHKMMA---------- +---MRALIVTTSH-GVLNATGKATGIALSELTHPYYSYLDAGMQIDVASIKGGQIPVDPSGLGRVMIPEDKRYLDDPILLA--KVENSLRIDDVDFNQYDAIFIVGGWGAAYDLGYSEELANKIGDAYYKEPLMGSVCHGALGFINVKDLN-GNKLIAGRAMTGVTDKQLKELNI-----ELTPLHPETELRKAGAVFESQTDVLATHVAIDARFITGQNQNSGLETAQKMIA---------- +---KRALVITTSH-AVLSKQGKPTGVFGSEMTHPYYTFLDGGMEVDIASIQGGELPIDPESFFFMVKPEDERYLNDPIAQA--KVKNSISIEAVDVNQYDIIFLSGGWGAAYDLAQSPALAIKVSESYYKEPIIGGVCHGVLGLVNARNNE-GNLLIAGRRMTGVTDKQISELGI-----EFTPKHPETELRKAGVTFESKTDIFATHVTVDDRFVTGQNQNSGLEMAHTMME---------- +---KRALIITTSH-GVLAPDGPATGVWASEMTHPYYVFLEAGMSVDVASIKGGEIPIDPQSFYRPIIAEDEHFLEDPTFQA--KVKNSIPIEQVDIGQYDTIFLAGGWGAAYDMAQSDVLAEKVSAAWYKSPIIGAVCHGLLGLVRATDQQ-GNLLVADRRMTGVTDKQLRELGI-----EVTPMHPETELRKAGALFEASTDIFQTHVVVDDRFVTGQNQNSGLEAAHRIVG---------- +---SRALIICTNH-NRLDPTNRPTGAFGSEFTVPYYAFINAGMDVDMASPRGGQIPIQPESWVWPLIDDDRRFKADNDAMQ--KFNNSKNIAEMNPDDYDVIFMAGGWGAAYDLMQSDDLADFVTRANAQGKILGSVCHGALGLCSAKGTD-GELLVKGRRVTGVTNNQINTFGI-----AITPKHPEEELRKAGAVFECKHDPFMTHTSVDGNLITGQNQNSGYETAHRILE---------- +---KRALIITTSH-DTLGDSGKATGVFGSEMTVPYYAFLDANIKVDIASIRGGEIPVEPNSMGWPLAPADYRFKEDAIAMA--KLNNSIAISDIDVTMYDVVFLAGGWGAAYDFAQSEDLANLVTQANANNAILGSVCHGALGLVNAKDTD-GSILIAGRKVTGVTDKQLEQLGI-----TLTPLHPETELRKRKALFEANTDMLATHVVVDGNLVTGQNQNSGAETSHRILE---------- +---KRALIVTTSH-GTLGDTGKATGVFGSEMTVPYYAFQDTGMDVDIASIKGGEIPVEPRSMGWPLAEDDLRFKEDSVAMA--KMTNSIPIKDIDPAKYDVIFMAGGWGAAYDFAQSEALASIITKANTNDTLLGAICHGVLGLVNAKDKD-GSSLIEGRRATGVTDLQIKQLGI-----DITPKHPETELRKAGAIYEANTDMMATHVVVDGNIITGQNQNSGYETAHRILE---------- +---RRALVICTNH-NRLDPLKRDTGAFGSEFTVPYFAFVNAGMEVDMASPKGGEIPVQPGSWSWPLVEDDRRFMADKKAMH--DLKNSKAIAGLDPNDYDVIFMAGGWGAAYDLMQSEELGDFITRANAAGKILGSVCHGALGLCGAKGLD-GEPLVKGRRVTGVTNNQINTFGI-----AVTPKHPEEELRKLGAIYECQNDPFATHTTIDGNLITGQNQNSGYETAHRILE---------- +---GKILFVITSH-GELGNTGKKTGYWLSEVTHPWKVLKDAGYEIDFVSPQGGECPVEGQDA----SPINKAFAQDLSAQR--KINFTMKPSEVKPEEYKAVFFAGGHGVMWDFPDNKELAAITSKIYENGGVVAAVCHGPAALVNVKLSN-GKYLVDGKKINSFTNSEEKGIGL----DKVVPFALETALVKHGAKFQCSD-NFQSHVVVNNRVITGQNPMSAMAVGDAIRT---------- +---EKVLIVVTSH-SQMGTTGEKTGYWMGEVTHPYKELVDAGIEVDIASIAGGKAPVDERSLAE--AATNQWFMANNQHNT--KLQQTLKLADLTASEYKAVLFAGGHGTMWDFPQDKVLQQFAADIYQNNGIVAAVCHGPAALLNIKLAD-GRYLIAGKQVTGFTNAEEEQVKL----TQVVPFSLQDQLVQRGAHFNAAA-NWQAKVVVDQRLVTGQNPQSAAAVGQAMVS---------- +---KRILVVVSSH-DT-KGEGQVAGFWFPELTHPVEVYHQAGFEVDIASPRGGLPPFDGFDL----KPVSQWFWTNPAYRG--KLGDTLKLSDVDPARYDAIQLTGGHGPMWDFADNPELQRIVAEIYQAGGVVGAVCHGPAGLLNVRLSS-GESLIAGRKLTGFTNEEEVAREY----DRLVPFELETALRDNGAIFEEAP-IFENRVVVDGRLITGQNPASAHAFGQAVTA---------- +---DSILIVATSE-TTLGETLIPTGAWAETIAEPYYTFRRKGYRVVMASIRGGPIPIDPASVAPQNKHTVKLFLADPEAQR--LMHHSLPVALVDSQDYGAIFIPCGHGIAWDGPFNKELRRLVEEAYATGKIIAAVDHGPAAIVHARNIK-LTPLVFRKDVTGFSNTEEEAVRR----AALVPFLLEDRIRDEDGIYVRALRDFDPYAVRTGQLITGQNWQSSKATADLVVD---------- +---DRILIVCTST-GILGDTDQQTGVWAEELAVPYYLLLKKGYLVDIVSIGGNKVPIEPLSVAPPYRAAIRRFLEDVELQT--KLKNTTSIAYVDPAPYVAVFIPGGHGIAWDGPFSKELMRVVESAYAGGKVIGAVCHGPAGLIGAKVTD-PQSILTDKQVTGLSNSEEESTGR----AALVPFLLEDKLKEVGAVYVRGVRDLGPYAIRAGQIITGQNPASSKRTAELVIE---------- +---RALIAVTSAH-APLYPDGKETGLFITEALHPFNVFKEAGFEVDLVSETGSYQADWLSQQKDWL-DEDRKVWEDSEFRK--KLDAGLRPGDFNPDNYGVFFASAGHASLIDYPDAKGLQAMAAKMYGDGSIISAVCHGGAIFPGVISP---KSIINGRKVTGFTTKGEEEEGI----KSWNRPTIEKAAADSGATYVSPPGPWDSFTQTDDRIVTGANPASAHATAVACVK---------- +---TKILVVMSAS-DTILLKH-PTGVFLNELYFPVKTLSEKGYEIVFATPFGKKVTIDPESTKEKYSEEAIRLLSS---FP--TYSKPISLEKGDHQSFVGILVPGGQGLMTDLLYDEKIPQLLKIFHQKQKPIGLVCHAPALLTTLHLEG-EKFIFKGYKVNSVTKIEEWFIEK----GTPKVRNISGSLKDLGMEYKSSFLPGRSYAIRDRNLITSQNPFSGTEFSELYWE---------- +---PKVLIVMSAA-SHLLLYH-PTGVFLNELALPAIRLNQSGFDLEFATPNGKKVTLDPESLKDKYSAEAIRFLNS---LN--SFQKPISLELQKNQSYIGLLIPGGQGLMSDLLYDTNLPILLRTFQKQEKTIGLVCHAPALLITLTEGP-DGFLFQGYRVNSVTKMEEWFIEK----GKPKVRKISELLKERGMLYESSFFPASGFATRDRNLVTSQNPFSGEDFTKLYLG---------- +-------------------------------------------------------------------------------------------------------------------------------------HGLVCHAPGVLRKVKAQN-GEPLVKGRRVTGFTNSEEEAVGLTNVVPFL----VEDSLKALGGDYSKGD-DWSVYVLTDGKLVTGQNPASSAQAAKDVLT---------- +----------------------------------------------------------------------------------------------------------------------------------------------MLRHVKKPD-GSPLVEGKRVTGFTNSEEEAVGLTNVVPFL----VEDALKAAGGQFERTD-DWGVHVVVDGHLVTGQNPASSAATAEALLK---------- +------------------------------------------------------------------------------------------------------------------------------------------------MQAKGAD-GEPLVKGKKVAGFTNTEEEAVQLTNVVPFL----VEDRYQELGGIYSKAD-DWQPYVVTDGLLITGQNPASSEPAAEALLK---------- +-------------------------------------------------------------------------------------------------------------------------------------LALVCHAPGVLRHTHNPD-GTPLVQGRKVTGFTNTEEEGVDLTDIVPFL----VEDELKRLGGDYSKTA-DWQPYVVQDDLLITGQNPASSGPAAEALIK---------- +---------------------------------------------------------------------------------------------------------------------------------------MVCHGPGALILATNPTTKKSIFAGARATGFSNSEEAQTPFVNILPFS----LEDKIKELGGKYEKADQDWGVKIIWDQGVLTGQNPASAGPLAVKLKE---------- +-------------------------------------------------------------------------------------------------------------------------------------LLLSCHGGAIFPGIIDPSTGKSVISGRKVTGFTTRGEEEEGVLDTIKSWKRPTIEASAADSGATYVSPAGPWDAFTITDGPIVTGANPASAHVTAEAAVK---------- +-------------------------------------------------------------------------------------------------------------------------------------LAAVCHGPAAFVGAKDKN-GNFLVSGKRINSFTNAEEKATPHYQDMPFL----LESKLIEQGAIFESSG-LREPHLAVDERVITGQNPESIELVTGAIHA---------- +----------------------------------------------------------------------------------------------------------------------------------------MCHGPVALLSTLPNPAKGWIYADYQMTTFSNSEETMAKGDDELHYW----PQDALTKAGGNYSRSEQDWHPHIVVDRELITGQNNKSAVGVAKTLLK---------- +------------------------------------------------------------------------------KTELNSLKNSVKLSQVDLSKYDAVYIPGGHGAIYDLPKSKEVKEAIEYFANKNKVVASVCHGPASFININ-LSDGTPFVKGKTLTSFTNKEEKEAN--LIAENELPFYLETELSKKGAIFIQK-PNWSDHIEVSENLITGQNPKSSKSVALAIVDK--------- +------------------------------------------------------------------------------------------MSQVNGEDYDAIFYPGGFGLLSDLATDESFAAIAAAHYENGGIIAAVCHGPGALLPIT-LSSGEKLLASKSVTGFTREEEIDFG----TIDAVPFLLEESLARTASRYNKV-QPWQELVIVDERVITGQNPTSAHGVGKALVES--------- +--------------------------------------------------------------------------------------------------------------MYDLAKNEELHNIINTIYDNGNIVAAVCHGPAPLIWTK-RPDGKSIIAGLKVTGYPEAVE-PAG----LPDILPYSLEGEMRKIAE-YTSE----EKVVWGNDQLVTGRDPFSSEALGKELVKA--------- +--------------------------------------------------------------------------------FQNRINNTIPVSQVNIADYDAIFYPGGFGLLSDLNTNEDFAKLAATHYENGGILAAVCHGPAGLLPVK-LSSGEPLLASKSVTAFTREEEIDYG----TIDDIPFLLEESLARNAAKYTKV-QPWQVFVIEDDRVITGQNPASAHAVGEAIIKW--------- +----------------------------------------------------------------------------------------MTLTSVDVSSVDAVFYPGGHGPLWDLAEDATSIKLIETLLAAGKPVAAVCHAPAALRHPK-GPDGKSVVAGKAVTGFTNTEEQAVG----LTDIVPFLVEDMLRQNGGTYSKL-ADWEPYVVTDCLLITGQNPASSEPAAKALLKL--------- +------------------------------------------------------------------------------AAAEAQLDETVRLDSVRQEDFDTLFYPGGHGPMWDLAEDKNSVKLIESFLAAGKTIAVVCHSTGALRHVK-TPDGKPLVQGKEVTGFTNGEEEDVG----LTKVVPFLVEDEMLKLGAVFSKT-ANWGVHVVSAGQLITGQNPHSSGPAAQTLLAA--------- +-----------------------------------------------------------------------------------MLANTGLLSEVNAADFDAVFYPGGHGPLWDLAEDPHSIALIEAFAKADKPHGLVCHAPGVLRKVK-AQNGEPLVKGRRVTGFTNTEEEAVG----LTEVVPFLVEDVLKELGGDYSKG-DDWSVHVLTDGKLVTGQNPASSAQAAKDVLTL--------- +--------------------------------------------------------------------------------------------------------------MFDFPDDENLKRLLQEFAEADKVIGAVCHGPAGLVNAE-LKDGTPLVQGKTVTSFTDSEERGVE----LEDQVPFMLETKLKERGASFVVA-DDWAEHVQTDGKLVTGQNPQSSIRVAEEFMKA--------- +--------------------------------------------------------------------------------------------------------------MWDLAEDADSIALIEAFAAANKPHGLVCHAPGALRRVK-GSDGKPLVNGRRVTGFTNSEEEGVG----LTKIVPFLVEDVLTELGGRYEKG-ADWGVHVVTDGLLVTGQNPASSEKAAEALLEL--------- +--------------------------------------------------------------------------------------------------------------MYDFARDPQVADWILAMSAAQKPVATICHGTAALTNPQLEVDGEAWVEGKRVTGYSNAEELYVG----HSDHVPFLLQDRLERMGADYVEA-NPFHSHVLTDGKLITGQNPQSTKELARTLAGL--------- +---------------------------------------------------------------------------------MAALAASVPLSRIDMNAFSGIFLVGSHGAMWDFPENKELTRLLDEAASSGKTVGAVCHGVTGPL----AASDPKFLDTRAVAGFSNEEEAAVG----LTEVVPFPLQTCLEAKRARYVAG-AAFSVHVQSDGGLVTGQNPASSVQTAKAMLQA--------- +---------------------------------------------------------------------------------MQALANTHKLSEVLNQDFDAVFYPGGHGPLWDLAKDQNSISLIEQSLQANKPVALVCHAPGVLRDVK-NAEGRPIVEGKSVTGFSNTEEDGVG----LTDIVPFLVEDTLKEKGGQYSKA-EDWQVHVQQDGLLITGQNPASSAATAEALLKL--------- +---------------------------------------------------------------------------------------------------------GGHGPLWDLANDYTSIHLIEETLQSNKPIALVCHAPGVLKKVK-DSEGHSIVSGKLVTGFSNTEEEGVG----LTNIVPFLVEDMLKENGGNYSKA-DDWQVHVQQDGLLITGQNPASSAATADALLDL--------- +------------------------------------------------------------------------------QNLADLLKETSPIDSVKASDFAGIFLPGGHGAMFDLPNNEHLHKLLRDFAESDKSIGAVCHGPAGLVGAK-LSNGEPLVAGKTITAFTDAEEYEVK----LEKEMPFLLESKLRELGATLVVR-SNWEDHVETDGKLITGQNPQSSISVAKEFLKT--------- +--------------------------------------------------------------------------------MAELLKHTIPLAELKSVDYDGIFMPGGHGAMFDLADNEQLQQLLRDFYVADKSIGSVCHGPAALTGVL-LENGEYLVSNRKLTSFTNTEEESVE----LVNQMPFLLETRLRKEGAIFLAK-DDWQENVYTDGKLVTGQNPQSSIETAKQFLKT--------- +------------------------------------------------------------------------------EAALEQLANTLQLSQVTADGFDAIFYPGGHGPLWDLSEDPLSIGLIQQFWEQDKPVAAVCHAPAVLVHAK-TPAGKPLVAGRKVSAFTNSEEAAVG----LTDVVPFLLEDKLQELGAHYQKV-DDWKPLAVVDGNLITGQNPASSAAVARALLQQ--------- +------------------------------------------------------------------------------PVALFAASNTRKLREIDYSTFDALFVPGGYGLLWDLAVDSYTIKMIRDFYESNRPVAMVCHAPAILRDVK-KSDGTYLVEGVKLTGFKNDEDTEIE----LLHHLLFSLEDELKRRGANYISK-ANWEANVVVDGALMTGQSPASAPPLAVVLRDV--------- +---------------------------------------------------------------------------------MTALEHTKSLSEISEETFDCIYLAGGHATMHDFPDNITLQQLILDQYEQNKIVAAICHGVGGLLNVK-LSNGEYLIKGKSLTGFDWFEETLAR----RKREVPFNLEAALKERGADLKKACIPMTSNVVVAGNLITGQNPFSSKEMAKVVIEQ--------- +------------------------------------------------------------------------------PAFRRMLQHTQSLDAISGKMFDCIYLAGGHGTMYDFPDNAVLQSIIKSHYESDKMVAAICHGVCGLLNVR-LSDGEYLVREKELTGYSWFEEILAR----REKEVPFNLEETPKKRGADYRKAFIPMTSKVLVNGNLITGQPPSVRKK----------------- +------------------------------------------------------------------------------KEIADQLTKTVPLEEINPNNYSGIFLPGGHGTMFDFPDDEQLKSLLQTFEEQKKPIAAVCHGPAGLVNAT-KKDGTPLVQDKYVTSFTDSEERGVE----LENQVPFMLEETLREKGAKFSAA-NDWAEHVQRDGLLVTGQNPQSSIKVAQEFIEA--------- +-----------------------------------------------------------------------------------MLANTFKPSDIHWQDYDVIYYTGGHGVMWDFLDNPELQEITKNIYEKGGIVSSVCHGYCGLLHVR-LSNGKRLIEGKKLTGFAWSEEVLAG----VAKKVPYNAEELAKEYGARYEKAFIPFAPYVVQDGNLITGQNPFSAKKTALAIIET--------- +--------------------------------------------------------------------------------------------------------------MWDFLDNAELQSITKNIYEHGGIVASVCHGYCGLLNVQ-LSNGQYLIQGKKLTGFAWCEEVLAG----VAKKVPYNAEELAKQRGALYQRKFIPFLPNVVRDASLITGQNPFSARVTAFAMIDA--------- +---------------------------------------------------------------------------------MQRLKTTLAPNAINPTQYKAIYYTGGHGTMWDFPNNKALQNISEQIYRQGGVVSAVCHGVGGLLPLQ-DENGKPLIAGRTVTGFANIEETLSG----IKSQVPFSLQNGLIERGAKYKEAFIPFTSYVVSDDRIITGQNPQSSKEIAEAVVKR--------- +------------------------------------------------------------------------------KEFMNRLGSTMKPSEVNPEDYAVIYYAGGHGVIWDFPENKELQNISRNIYENGGIVSSVCHGAAGLFHIT-LSNGDRLISGKKVTGFSNEEEKLAE----LDQFVPFLTEDELIKNGGLYEKAAQPWEAFALEDNRVITGQNPASGGPVAELVLKQ--------- +------------------------------------------------------------------------------HKYEKQLKSPLKLADISDSPYAGIFIPGGHGVLAKIPESKEVKALLKWAVDNDKYVITLCHGPASLLAAAVN-PNDYIFKGYQVCVFPDSLDKGANI-DYMPGQLPWLVGENLEKLGVEILNK--GITGQVHQDRKLLTGDSPLASNNLGKLAAET--------- +-----------------------------------------------------------------------------------MLEKPKKIEDINLDGYAAVFIPGGHGCMVNLPACQPLGKLLNQAHARALPTVTLCHGPCALLATCASGEAQCTYAGYKTMCFTDKTDA-FTP-SYLPGPMPWKVEECLVAKGVEVLNK--SETGAVTQDRELITGDSPDAAHNLGVLAAPL--------- +------------------------------------------------------------------------------QKYADKLKNPLKLADIENSPYAAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVQ-PENYIFKDYQICVFPDSLDKGANI-DYMPGALPWLVGENLEKLGVKILNT--GITGQCHRDRKLLTGDSPLASNNLGKLAAET--------- +------------------------------------------------------------------------------EKYKEKIRSPLNLHNVNDTPYLAVFIPGGHGVLNGIPFSETVGNVLRWAHENKRYFITLCHGPASMLAADVPEGSKFIYDGYQIDVFPDTLDDQANV-EYIPGKMEWYVGERLRKLGITPLNR--GIDGAVYRDRLVLSGDSPLASNNLGKLAAKT--------- +------------------------------------------------------------------------------AGLLHDLKLTSRIEQIGVGQFDAIYIPGGHAPMQDLLKDKQLGKVLTAFHKAGKPTALVCHGPIALMSTLPVKTGEWIYKNYQMTVISNQEEEQAKS-LLKGGEMKFYPQTALESLGAKYQSNTKAWSPNVVVDRELITGQNPASAVLVGKSLLEK--------- +------------------------------------------------------------------------------KELLEKLALTERVEQQGYARFDAVYIPGGHAPMQDLLKSPALGRLLADFHQRNKTTALVCHGPIALLSTLPPATPKWIYSGYQMTVISNQEEEQAKP-LLGGGEMKFYPQTALQRAGATFSSNATPWTGHVVVDRELITGQNPASALEVGQRLVER--------- +------------------------------------------------------------------------------FRLKAY-ASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCAT-NEDRSWVFHGYSLTGPSVCELVRAP----GFARLPLVVEDFVKDSGACFSAS-EPDAVHVVLDRHLVTGQNASSTVPAVQNLLFL--------- +------------------------------------------------------------------------------FRLKAY-ASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCAT-NEDRSWVFHGYSLTGPSVCELVRAP----GFARLPLVVEDFVKDSGACFSGA-AASCPKA--DRHW--------QHFPVEEIFLA--------- +------------------------------------------------------------------------------PANRQLLSSPLSVAELIVMGYWGLVLPSSLGGVSDLAHDAALGNLVKKFVAAN-----------SL-CKAFSDSDKWCFSGWNLTAVSNFEVARYP----FFSKLPLIIEDFVKDHGGFYNCS-VMDAVHVVVDRSLITGQNDNSTALAVQNFVWL--------- +------------------------------------------------------------------------------FRSKGL-SNPHKLEEIDSSKFMTLVIPDSPGALFDLSNNAELAGIINSFTRDKKPMCAIGYGVAALFSTLDIHSQKWYFDKHSLTAPSHAEILKRE----DFPSLPIVPPDFIRKHGGTYSASPDPSSLYVVVDNFLVTGQNEQSTLTGVQNLILL--------- +-EQKHILMVLSSYGETDAQGLIKPGYEFDEMSKSYLVFKAAGAKVTFASPKGGKNKAKQYNA-KFLDDKSA----------VAQLENTQKLATLNHQDFDAVYVVGGKGPMFDLATDNSVKQIIKQVYENDGVIGAVCHGPAALLDVK-LSSGEYLLAGKRVSGFTNLEESAFTKKWQ---M-PFSLADKLSEQGALYQQ-DSLMFNQVSFDGNLLTGQNPFSTTDTAIAVAKK--------- +-ASERVLLVVSSAGTAE---DPESGYEFDELTQAWWTFVDNGYEVEIASPAGGENPMWAHNT-RFLEDAQA----------MAAIANTVPLAEVSAADYDAVFLIGGSGAAIDLPQDPHLQALVEAVYGSGGVIGAVCHGPAGLVNAE-LA-GRPFLEGRHLTAFTNAEEALFGDKEGK----GWSLEDRIVEEGGRFDA-GGIMHLHVVEDGRLVTGQNPFSTALTAEATIRA--------- +-DEKRVLMLISSYGTEA---NPELSYDLEELAQSYLVLHDNGVKLDIASPKGGAKDSLDYIQ-RFKA--LA----------TEKLANTLATEDIDISQYDGVFIVGGAGAMLDLPAHEATQQLLTHAVQIDKVITAVCHGPAAIADIK-LSDGSYFVAGKQVNGFTNVEEQAFSGEHVA-QF-PFLLQDRLIKNGARFVQ-NAPMLPYVAVDGKLITAQNPGSVAKAAEAMVLA--------- +-DQKKVLMVVSSYGKDLG--ATRPGFEFDEFSQAYQIFKQNGLHIDVSSPKGGKNKEKAYNM-AALEDQKI----------LEVLENTTATSQVDPTRYDAIYVVGGKGAMFDLPYDPSLQDIILDLYRRSTVISSVCHGPAAFVNVK-DGD-HYIIKGIEVTGFCNIEEELFGKKWVA-EF-PFKLEDKLKSRGAVFSQ-ADFMLSHVAVSGKFITGQNPFSTTRSAEEVVKA--------- +-NQKNVLIIVSSYGKDNG--KTRPGFEFEEFVDAYNIFTSNNSKVTVASPKGGSDATKEKNN-AFFTNKNT----------ASILSQTVATSQVDADDYDAIYIIGGKGAMFDVPYDPSLQDIILNLYNRGTVLASVCHGTSAFINVK-HQN-NYILDNERITGFSNEEEKIFKSKWID-EF-PFLLEDAVKSRGAKYQK-SSFMLENVVISGKFITGQNPASTKVSAEAVVNA--------- +-AQSNVLIVLSSYGELNPQQLVKPGYEFGELAKAYYVFKRHGIEVTLASPHGGKDKAAMYNK-RFLNDETA----------VSALSQTHKLDEIDIDKYDGVFVVGGKGPMFDLYQSEPLKKIIAKLYENQGVIGAVCHGPAALVDVK-LSDGRYLVEGKRINGFTNAEEHAFGSKWLK-DF-PFLLQDKLTERGAKFEQ-DAVMLNHVTIDGSVITGQNPFSTVDTARAMVDA--------- +-TQSNVLIVLSSYGELNQQQLVKPGYEFGELTKAYYVFKRHGIEVTLASPLGGKDNSALYNK-RFLNDEAA----------VSALEHTYKLDEIDIDKYDGVFVVGGKGPMFDLYQSKPLKRIISKSYENHGVIGAVCHGPAALVDVK-LSDGRYLVEGKRVNGFTNAEEHAFGSKWLK-DF-PFLLQDKLTERGAKFEQ-DSVMLNHVTIDGRVITGQNPFSTVDTARAMVAA--------- +-DSTNVLVVISSYGEVNQNQLVKPGYEFGELSKAYHVFKRHGIQVTIASPSGGKDKSAIYNQ-KFLNDEAA----------LASLTNSYKLADIDASKFDGIFVVGGKGPMFDLHQHEPLKQTISKIYENSGVVAGVCHGPAAFVDVK-LSDGRYLVAGKRVNGFTNAEEHAFGSKWLK-DF-PFLLQDKLEERGAKFEQ-DGVMLNQVTVDGRLITGQNPFSTVDTARAMVTA--------- +-DEPHVLMVLSSYGKQV-DGTTQPGFEFDELSKAYQVFSNNGIQVTLASPAGGQNKDKSYNQ-AFLNDQQA----------MSALSDTVKLASLNGQSFDGVFIVGGKGPMFDLHQDNELQRLIREIYEQQGVVGAVCHGPAALVDVK-LSNGDYLVDGRRVNGFTNLEETAFGKKWRP-QF-EFLLEDKLKERGGLFEQ-DGLMLNQVTIDGRLITGQNPFSTADTAVAMVRA--------- +-EEPHVLMVLSSYGKQV-DGTIQPGFEFDELSKAYQVFSDNGIQITLASPAGGQNRDKSYNK-AFLSDPQA----------MNALSDTVKLASLDGQAFDGVFIVGGKGPMFDLYQDSELQRLIREIYEQQGIVGAVCHGPAALVDVK-LSNGAYLVDGKRVNGFTNLEETAFGKKWRP-QF-EFLLEDKLKERGGLFEQ-DGLMLNQVTIDGRLITGQNPFSTADTAMAMVRA--------- +-DAPKVLLVLSSYGEKNAQGMIKPGFEMDELSKAYLVFKDHGLDIELASPQGGKNPEKSYNQ-QFLADSNA----------MEKLQNTLALSSIDPADYRSVFVVGGKGPMFDLAQNQHLQATIRTIYENHGVVGAVCHGPAALTKVK-LSTGEWLVANKRVSGFSEEEEAAFSKKWAS-QF-PFQLESMLIEQGATYVQ-DGLMLNQVSIDGNLITGQNPFSTVDTVKAMIKA--------- +-NTPHVLMVLSSYGEMGTDGLSKPGFEFDELSKAYAVFKQNGIKVTLASPKGGEDKNKPYNQ-AYSNDTTA----------MAQLKNTKRLSELEPSQYDAVFVVGGKGPMFDLHDSKPLQAIIRDIYVKNGVIGAVCHGPAALVDVK-LENGEYLIAGKRVNGFTNEEEAAFGKKWTK-QF-PFLLEDKLIERGASFVQ-DGLMLNQVSIDGQLITGQNPFSTVDTAKAMVAA--------- +-VSKKILMVVSGYGQE----EKSAGYEFDEFSKAYLVFKANGISVDIASPKGGKDATAAYNA-KTLADKNI----------MDKLAQTLATSDIDASKYSGIFIVGGKGAMFDLPKDKALKTLIADIYQQQGTVAAVCHGPAALVDVK-LNDGSYLVANKAINGFTNTEEQLFGKKWLS-KF-DFMLEDKLIERGGKFQS-SDIMLSHVAIDDRLITGQNPSSTVGVANALVSS--------- +-VNKKVVMVVSGYGQE---QEKTPGYEFDEFAKAYGVFKANGITVDVASPKGGQDPKKPYNA-KVLADKAI----------MAKLDNTLASAQLDATAYDAVFIVGGKGAMFDLPKDESLQALIADIYQQQGTVAAVCHGPAALVDVK-LSDGSYLVANKKVNSFTNKEEKLFGKKWLS-KF-EFMLEDKLAERGARFQS-SEIMLKHVAVDGRLITGQNPTSTVAVATALVKS--------- +-VNKKILMVVSGYGQE---QETAPGYEFDEFAKAYNVFKANGITVDVASPNGGKDPEKSYNA-KVLADQAI----------MAKLDNTLSTAKLDPKAYGGVFIVGGKGAMFDLPKDEALQSVIADIYQQQGAVAAVCHGPAALVDVK-LSDGSYLVANKKVNSFTNKEEKLFGKKWMS-KF-DFMLEDKLAERGAKFQS-SDIMLSHVAVDGRLITGQNPTSTVAVATALVER--------- +-DSKRIVMVLSGYGQP---EQQAPGYEFDEFAKAYLVFQAHGIAVDIASPQGGNDPAKPYNQ-QVLNDAAI----------MAKLNNTLSTAQLRAADYSGIFIVGGKGAMFDLPKDPALQQLIAGIYQQQGSVAAVCHGPAALINVK-LADGSYLLANKAVNGFTNEEERLFGKKWLA-QF-DFMLQDKLIERGGRFEH-SPMMLSHVAVDNRLITGQNPASTVATARALLQS--------- +-VNKKIVMVVSGYGQQ---QAITPGYEFDEFSKAYSVFNANGIAVDIASPNGGKDADKPYNA-RVLTDQAI----------MAKLGNTIATDKLDANAYDAIFIVGGKGAMFDLPKDQALQTVIAKIYQQQGAVAAVCHGPAALVDVK-LNDGSYLVANKAINGFTNKEEHLFGQKWLN-KF-EFMLEDKLTERGAKFQS-SEIMLSHVAVDGRLITGQNPTSTVDVATELVKS--------- +-QDLTVLMVVSGNGQS---KEVQPGYEFDEFAKAYLVFQAHNIAVDVASPKGGADPNKAFNA-QVLADTEI----------MTKLNNTLAISTLNANDYDAVFVVGGKGAMFDLPKDAALQQIIADVYEQKGVIAAVCHGPAALVDVE-LSNGEYLVAGKRVNGFTNNEEQLFGKKWLP-HF-EFLLEDKLGERGGVFQS-SDIMLEHVAVDGRLVTGQNPSSTVGVAIAMLET--------- +-ETKKIVMVISGYGQQ---QEPKPGYEFDEFAKAYRVFRDNGIAVDVASPQGGKDPGKPYNA-KVLADAEA----------MAMLNNTLATTALNAQNYDAIFIVGGKGAMFDLPKDEALKTAIANIYQQKGTVAAVCHGPAALVDVK-LSDGSYLVANKAVNSFTNQEEQLFGKKWLS-KF-EFMLEDKLVERGAKFQS-SDMMLSHVAIDDRLITGQNPVSTVGVATALVTS--------- +-LKPKVLLVASSYGVADD--PKKPGLEFDEYAMAYQLLS-PQVQLELASPKGGKNKTKPYNA-VVLATPAA----------MQLLISSKKLSEVKAEDYQAVLVLGGKGAMFDLADHQPLQQLLADMAEQQKVIAAVCHGPAALIHVK-NKDGSLLLQGKKVAGFSNQEERMFAKEMLP-LY-PFLLQDGLTKAGALYQQ-TGPMLPFTVQDGTLITGQNPYSTPALIDAILAQ--------- +-AKPKVLLVASSYGVAGD--PKKPGMEFDEYAMAYHLLS-PQLQLELASPKGGKNKTKSYNA-AVLTHPDA----------MALLTNSKKLSDVKARDYQAVLVLGGKGAMFDLAEHLPLQQLLSDMAAQQKVIAAVCHGPAALVHVK-NADGSLLLQGKKVAGFSNQEETMFAKEMLP-LY-PFLLQDALTKAGALYQQ-TGPMLPLVVQDGTLITGQNPYSTPALVDAILAQ--------- +-VKPKVLLVASSYGVADD--PNKPGMEFDEYAMAYHLLS-PKVELELASPKGGNNKTKPYNA-AVLASAEA----------MTLLTNSKKLSEIKAQDYQAVLVLGGKGAMFDLADHQPLQQLLTDMAAQQKIIAAVCHGPAALLHVK-NADGSLLLQGKKVAGFSNLEETMFAKEMLQ-LY-PFLLQDALTTAGALYQH-TGPMLPLTVQDGKLITGQNPYSTPAVVDAILAQ--------- +-QPPRVLLVVSSEGRDQG--RIRPGFEMDEFAQAWLILRRNGFEIDVASPRGGANAAEPFNA-AVLADPLA----------VRALAATLPTAQLRAGDYRGVLVIGGKGAMFDLPADSALQRTIATIWEQGGVVAAVCHGPAALAGIR-LGNGRALVEGRSMTGFSEEEEALFGKRWAK-EF-AFQLEPRMRELGARWQE-APLMMPKVVVDGRLVTGQNPYSTPVLAEAFVRA--------- +-QNNRVLLVVSGHGLEEG--KARPGFEMDELTQAYAVFADNGLQVDIASPAGGVDRDKPYNE-RFLADPIA----------TAKLNATLSVASLDKQNYAAIFIIGGKGAMFDLPVDVQLKALLAQTYQAGGVIGAVCHGPAVLMNIS-LPGGVSLLEGRSVTGFSNEEEALFGKGWAR-AF-PVLLENGLRGSGAQFSD-APMMLSHVVTDGRLVTGQNPYSTAAAAEAVIRA--------- +-TAPGVLLVVSSEGRAE-GTINRPGFEMDELAMAWLTLRANGLQVQIASPAGGANPREDHIA-AFLADADG----------VRQLQQTRRTEDVKPGEHAAIFLIGGKGAMFDLPRDTALLQLLAAH---QGVLAAVCHGPAALLNVR-TPDGRPLVAGRRMTGFSDEEEKLFGKKWAK-EY-PFWLETRARELGAQWEE-APLMMPKLVVDGPLVTGQNPFSTTLVAEAIVRQ--------- +-AKDTVLVVLSGEGRDAG--QTRPGYEFDELSQAWAIFRANGLAVELASPQGGADPGAPANA-ALLADDAT----------MRQLADTRRIADLRAEDYAAVYIVGGKGAMFDLPREPALQTLLGQAWDRGAVIAAVCHGPAALVDVH-LADGSLLVEGRRMTGFSNEEQALFSKRWGA-EF-PWLLEDTLRERGAIWDE-APLMMPKLVVDGRLITGQNPYSTPAVAEAIVRG--------- +-EAGRLLIVVSGEGREQG--KTRPGYEFDELSQAWLIFKANGFAVDVASPQGGANPQEPFNA-ALLADADA----------MRVLADTRKTGDVKATDYTAVYVVGGKGAMFDLPRDPALQSLLADAYDGGAVIGAVCHGPAALADVR-LRNGASLVHGRNVTGFTNEEEALFGKRWAK-EF-PWLLEDRLRERGARWHE-APLMMSKVVVDGRLVTGQNPYSTPAVAEAIVRA--------- +-APPKVLLVVSSEGRRDDKGLTRPGFEMDEFAQAWLVLRANGVQVEVASPTGGANRDDDTIQ-ALQRDPEA----------QAALAATRRTQDVPVGAHAAILLIGGKGAMFDLPRDAALARLMGAHHKRGGVLAAVCHGPAALLAVQ-GPEGRPLVQGRRLTGFTDEEETVFGKKWAK-SY-PFWIEQRARELGAQWEE-AALMMPKLVVDDRLITGQNPFSTPLVAEAVLRA--------- +-AADKILIVVSGEGRDQG--KTRPGFEMDEFAQAYLIFRDNGYAIDVASPNGGRDATEAFNA-SLLADADA----------TAQLAATRKTGDLKAADYAAVYVVGGKGAMFDLPADPALQRVVADIYERGGVVAAVCHGPAALVDVR-LGNGAWLVDGKRMTGFSNEEEAVFGKRWAK-QY-RFQLEDALKARGAQWQE-AALMMPKLVVDGRLITGQNPYSTPAVAEAIVGA--------- +-ATDKVLIVVSGEGKDAG--KQRPGYEFDELSQAWLVFKANGLQVEVASPQGGANPDEPFNA-ALLADAQA----------MRQLADTKATAAVKASDYAAVYVVGGKGAMFDLPRDQALQQLLGKVWDNGGIVAAVCHGPAALAEVR-LADGSLLVAGRQLTGFSNEEEAIFGKKWAP-QF-PWLLEDALRQRGAQWQE-APLMMPKLVVDGRLITGQNPYSTTAVAEAIVRA--------- +-STDKVLIVVSGEGKDAG--KQRPGYEFDELSQAWGVFKANGLEVEIASPKGGPNPAEPFNA-ALLADKEA----------MRKLADTQATSTLEADDYAAIYVVGGKGAMFDLPRDASLRQLAGRIWDNGGIVAAVCHGPAALVDVR-LADGSLLVNGRKLTGFSNEEEALFGKKWAA-EF-PWLLEDTMRQRGAQWSE-APLMMPKLVVDGRLITGQNPYSTYAVAEAIVRA--------- +-APEKVLIVVSGEGRDQG--KTRPGYEFDELSQAWLIFKANGLQVDVASPQGGANAQEPFNA-ALLGDAEA----------MRTLAATRPTRDVKAADYAAIYVVGGKGAMFDLPRDTALASLLAEAYTQGAVIGAVCHGPAALVDVK-LGDGTMLVAGKAMTGFTNEEEAVFGKRWAK-EF-PWLLEDALRGRGAQWQE-APLMMAKVVVDGRLVTGQNPYSTPGVADAIVRA--------- +-AASRVLLVVSSEGRDQG--KTRPGFEMDEFAQAWLILKQNGFDIDVASPRGGANPTEAFNS-AVLADSQA----------MGKLAATLPTAQLRASDYQGVLVIGGKGAMFDLPADKALHATIAGIWQQGGLVAAVCHGPAALAGVR-LPDGRAMVEGRAMTGFTEEEEALFGKRWAK-EF-TFQLEPRMRELGARWQE-APLMMPKVVVDGRLLTGQNPFSTAALADAFVRA--------- +-ASPSVLIVLSSAGRDGG--KTRPGFEMDELAQAWGIFVDNGLQVKLASPAGGKNARDAANA-RLLAHAGV----------MAQLGATARIDELDPAAYDAVYVVGGKGAMLDLAEHPGLAALLGRVYDRGGLVAAVCHGSAALAEVR-LADGRRLIEGRRVTGFSAEEESVFGKKWSQ-AF-PFVLEDGLRARGARWVE-APLMMPMLAVDERLITGQNPYSTHAVAEALVRG--------- +--TKRVLMVVTNHT--TITDDHKTGLWLEEFAVPYLVFQEKGYDVKVASIQGGEVPDPRSINEKDP----------SWAEAEAALKNTARLSRDDAHGFDAIFLPGGHGTMFDFPDNETLQYVLQQFAEDGRIIAAVCHGPSG---------------------------------------------------------------------------------------------------- +--TMKILMVLTSHD--RLGNGKPTGFWLEEFAAPYYVFKDAGAEVTLASPKGGQPPDPKSDEPASQTAAM--GRFKDDPAARKALANTLKLGEVKQEDYDAVFYPGGHGPMWDLVNDRNS--------------------------------------------------------------------------------------------------------------------------- +---MKILMVLTSHD--QLGDGKKTGFWLEEFAAPYYVFKDAGADITLVSPKGGQPPDPKSDEPDAQTEAT--KRFKQDTDAQQALASTQRLADVKAADFDAVFYRVAMARTWPKTRIRSR--------------------------------------------------------------------------------------------------------------------------- +--MSRILMILTSHD--QLGDGRKTGFWLEEFAAPYYVFCDAGHDVTLASPRGGQPPDPSSSLPQMQTDAT--RRFDVDEQAKRALTTTTPLSEVDIATFDAVFYGWPRSARSHLAADHR---------------------------------------------------------------------------------------------------------------------------- +---MKVLFVLTSHD--QLGDGKKTGFWVEEFAAPYYTLADAGVKVDLASPKGGQPPDPKSTEKDAQTEAT--RRFYEDDDLQHKLSKTKKLSEVKADDYDAVFFPGGHGPLWDLATDKDSIRLIESFAKQQKPVAAVCHGPAA---------------------------------------------------------------------------------------------------- +--TKRILNVVTNVA--HYDEEHPTGPWLSELTHAWHVFDEHGLEQTLVSPSGGKVPEPRALKFPNYDKTA--KAWRADPGKMALLESTRSPDEIDSADYDAISFTGGHAVMYDFPDSIGLQRITREIYE------------------------------------------------------------------------------------------------------------------ +--MKPLLILATNQN--HYEGEIPTGLWLGELTHFIAIMEEKGLPYQIASLKGGEIPDPFSLTEQFMDQES--MDYYDDLAFMSSLVNSLALDKLEPADYSGLYFTGGARGYV----------------------------------------------------------------------------------------------------------------------------------- +--NKRILFVVTNHT--QLGNGETTGYFLSEVTHPLEVLTAAGYKVDFVSPKGGTATYGVKL----DDPIN--KKYWESADYQKQLAHTLAPSQVKAEDYAAIFYAGGHGTMWDFANSEALAK------------------------------------------------------------------------------------------------------------------------- +--VKRALLVVTSHT--EMEGGKKTGFWFDELATPYWHFYDAGYEVTIASIKGGKALDPLSIDGEFATPEV--HRFKSDKKALEKLAHTPCVDDLDASGFTFIFLCGGHGTLWDFKQSKGLRAW------------------------------------------------------------------------------------------------------------------------ +-----------------------TGNHPVEMLLPMFHLDNAGFEIDIATLSGNPAKEMWAMPKQEQVVLD---TFQKYADKLNPLKLADILENAENSPYAAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQDKFIITLCHGPAS---------------------------------------------------------------------------------------------------- +--KPSILFVLTSHN--KLGSDKPTGWYLPELAHPYHVLR-NKANITVASPKGGEAPDPASVEAAKDDVSV--SFLQNDSQVW---KTTKKLSDFKAKDFDAIFYVGGHGPMFDLVDDPTSQALIREFWEADKIVSAVCHAPAV---------------------------------------------------------------------------------------------------- +--KKKMLVVLTSVE--KYPNNRATGLWLGEAVHFVKKVEEAGYKVDYVSPQGGYTPDPHSLAMAE-SIDW---EWYQKKEFMNRLGSTMKPSEVNPKDYAVIYYAGGHGVIWDFPENKELQMISRNIYENGGIVSSVCHGAAG---------------------------------------------------------------------------------------------------- +--SKRILHVVTNVS--EYKGHRPTGLWLGELTHAYDEFEKQNYFQDIVSPLGGHSPEPKSLERFVADASV--LKRKNDPAFMQLLETTKKPSEINWQDYDVIYYTGGHGVMWDFLDNAELQDITKNIYEKGGMV------------------------------------------------------------------------------------------------------------- +--MKKILIVETNTS--RYKNNEPTGLWLGESAEFVDELQKHGIKYDFVSPNGGLVPDPRSMKY--MDEAI--WNVYEDKDFLRGTQNTLKPNEIKPNEYSAIYYTGGHGVMWDFPDNSEIQAIARQIYMNNGYLVSVCHGIAG---------------------------------------------------------------------------------------------------- +--DKPVLCVVSSHP--IKGAGVPTGFFLAELTHPLKVLEDAGLKTTIASIRGGQPPDGFDL----SDPVN--AWFWNETDFQQRLASTPALSELNGANYSAVFFAGGHGTMWDFRDSPDAQRIIREVYESHGIVSAVCHGPAA---------------------------------------------------------------------------------------------------- +--MTKALIVVTNTA--KFPTNRATGLWLSEATHFNKVMKDNNIDVDYVSPNGGYVPDPGSLAPDSMDETN--WSFYNEEKYRQVLGQSLSAKQVDPKDYDIIYFAGGHGVMWDFPENKALGEIAKTIYDRGGIVSAVCHGVVG---------------------------------------------------------------------------------------------------- +--MKKVLIIETNVN--RYKGDEATGLWLGESAEFIDEFQKCNIDYDVISPKGGLVPDPRSMKY--IDSSI--WNIYESSDFARAIRNTMRPEDINPKDYVAIYFTGGHGVMWDFPDNKKIQAIARVIYNDGGYLTSVYHGIAG---------------------------------------------------------------------------------------------------- +--SKRILHVVTNVS--RYKNDEPTGLWLGELTHAYDEFEKQGYVQDIVSPNGGKTPEPKSLVPLVADKSV--KDREKDQAFITLLANTFKPSDINWQDYDVIYYTGGHGVMWDFLDNPELQEITKNIYEKGGIVSSVCHGYCG---------------------------------------------------------------------------------------------------- +---MKILMVLTSHD--QLGDGKKTGFWLEEFVAPYYAFKEAGADITLVSPKGGQPPDPKSDEPDAQTDDT--KRFSKDADAQKALASTGLLSGVNAADFDAVFYPGGHGPLWDLAEDKHSIALIEAFAKADKPHGMVCHAPGV---------------------------------------------------------------------------------------------------- +---MSVLFVLTSHD--VLGDGRKTGAWLEEFLVPYYQVIDAGLLAFIATPAGGQAPDPLSVDALRDTAIY--RRFVHDETIQGALANTGWLPEITGNAYSAVIYPGGHGPLWDLRTNRESIALIGSMLQQSKPVATICHAGCA---------------------------------------------------------------------------------------------------- +---MKVLMVLTSHD--KLGDGHATGFWLEEFTTPYYTFLDAGADITLASPKGGLPPDPNSTQEDAQTETT--KRYDADQDLKSKLANTLELSGVSADDFDAIFYPGGHGPLWDLSEDKDSIALIEAFSAQAKPVGAVCHGPAV---------------------------------------------------------------------------------------------------- +--TKKILIVLTSHA--ELGDGHKTGFWIEEFAAPYYAFIDAGAEVTLASVQGGQPPDPNSTAPDAATDAT--KRFDNDSAAQTLMANTKLLSEVNASDFDGVFYPGGHGPLWDLVDNTDSIALIEEFINTEKPVAAVCHASAV---------------------------------------------------------------------------------------------------- +--NMKILIVLTSHD--QLGNGKKTGFWLEELAAPYYTFIDSGAEVTLASPQGGQPPDPKSNLADAQTETT--HRFEADPTAMQALAQTHKLSEISVADYDAVFYPGGHGPLWDLAEDPISISVIEQAIQSGKPVAAVCHAPGV---------------------------------------------------------------------------------------------------- +----KILAVVTNVD-KM-GENKATGYEHTELARAYWVFIANGFSVDIASPQGG-------KPPVVIDGEDMGAYDYNDKAIQQQVANSIPLANINPDDYEAVYFVGGKGTMFDFPNNPHIHNIAKTLYQNNKVVSAVCHGPAALVNVK-LDNGEMLLSNKNVSAFTNEEELFLIPDAK--QIFPFLLQDKLISQGAQFQAG-ITYLEKVTQDGKLITGQNPWSVWALAELVVS---------- +----RVLAVVTSTA-SL-GDGRRGGYELTELSRAYYTFLANGYEVDIASPDGG-------EPPMRTD-DDMVAADYNDPQARRKLAATLPLASVDPSAYAAVYFVGGKGTMFDFPGNPAIHDLVRTVYQSGGVVGAVCHGLAALLEVV-LDDGTPLLRDRRVTGFTNAEELFLIKDAR--AVFPFLLQDGLERAGAQFVEG-AMYLDNTVVDGRVVTGQNPWSTWSVAEAMVR---------- +----RILAVVTSTS-HF-PGEKKAGFELTELARAYYVFRANGYDVDIASPRGG-------PPPMRVDDEDMVAADHNDAEARKNLDASLPLREVDPARYAAVYFVGGKGTMFDFPDNVDIQRLVREVYQAGGVVGAVCHGPAALLEVT-LDDGSPLLRGRRVAGFSNDEELFLIEDAR--TRFPYLLQDRLVEKGARYVEG-PMYLDNTVIDGRIVTGQNPWSTWSTADAMVR---------- +----KILAVVTSTS-HF-PGDKKAGFELSELARAYYVLQANGYEVDIASPQGG-------SPPMRLDDEDAVAADYNDAAARRKLDGSLPLREVDATRYVAVYLVGGKGTMFDFPDDPDLQRIVRTVYQRGGVIGAVCHGPAGLLEVM-RDDGTPLLRGRRVTGFSNAEELFLIQDAR--VRFPYLLQDRMVEKGAQYVEG-TMYLDNTVVDDRLVTGQNPWSTWSTAEAMVR---------- +----KILAVVTSVD-KM-GEDQDTGYEHTELARAYWVFTANGFSVDIASPKGG-------KPPVVIDGEDMGAYDYNDDTIQQKVANSIALAEVNPNDYEAVYFVGGKGTMFDFPDNPYVQNIAKTLYQNNKVVSAVCHGPSALVNVV-LDNGEMLLSNKKVSGFTNNEELFLIPDAK--QIFPFLLEDKLIEQGAQFQSG-TTYLEKVTQDGKLITGQNPWSVWTLAEKVVA---------- +----KILAVVTSTD-KM-GQDKETGYEHTELARAYWVFIANGFDVDIASPKGG-------KPPVVIDGEDMGAYDYNDGAIQQKVANSIALADVNPNDYEAVYFVGGKGTMFDFPDNPHVQEIAKTLYQNNKVVSAVCHGPAALVNVE-LDNGEMLLANKQVSGFTNDEELLLIPDAK--EIFPFLLEDKLIEQGAEFQAG-TTYLEKVTQDGKLITGQNPWSVWGLAEKVVA---------- +----KVLAVVSSAA-HL-GAGKRAGFELTELSRAYYVFLANGYDVDIASPKGG-------RPPMKVDD-ELVEADHNDTQAQAKLAATLPLAQVDPADYAAVYFVGGKGVMFDFPDNPDIQRITAAIDARGGVVGAVCHGPAALLNVR-RPDGRRLLAGRQVAGFSNAEELFLIKEAR--TIFPFLLQDQLRKVGARYSEG-PLYLDHTVVDGRLVTGQNPWSTWSVAEAMVR---------- +----KILAVVTSTE-TM-GNGKSTGYELTELSRAYYVFEANGFEVDVASPLGG-------KPPIVIDDDDMGQFDYNDSIAQYKTSHTIAVNNVKAEDYQAIFFVGGKGAMFDFPENKAIQDIVKMYYQSDKVVGAVCHGPAALVNVT-LDNGRHLLENKTISSFTNKEELLLIPEAE--SIFPFLLQDKLAAQGAQFNEG-AMYLNKVSHDKNLVTGQNPWSTWTLAETMVK---------- +----RVLAVLSSTA-RF-DQRRKGGYELTEISRAYWVFQANGYEVDLASPAGG-------RPPQTLDD-GLVDADYNDPAVEAKLADTIPLARVDSSRYDAVYFVGGKGAMFDFPGNPDIARIVRDIAP-RGVIGAVCHGPAALLDIE-LPDGRPLLSGKRVTGFSNAEELFLIEQAR--NVFPFMLQDALAGQAGAFVEG-PMYLDNTVVDGNLVTGQNPWSTWSVAEAMVR---------- +----RILAVVSSAG-HF-PGGKPAGFELTELSRAYYTFIANGYAVDIASPQGG-------SPPMRVDDEDMVAADHNDVPARAMLAASLPLEQVDASRYAAVYFVGGKGAMFDFPGNTAIARIVRHIHGAGGVIGAVCHGPAALLDVT-LDDGTSLLQGRSVTGFTNAEELFLMKDAR--QRFDALLQDALVRRGARFVEG-GLYLDNTVVDRRLVTGQNPWSTWSVAEAMVK---------- +----RILAVLTSED-TL-GAGKSTGYELTELARAFYVFQANGFTVDIASVEGG-------EPSMVVDADDMGKFDYNDEKAMFKVKNSFAIKRANLAIYDAIYFVGGKGAMFDFASDVSIKAAVSYFWQTNKVIAAVCHGPAAFVDVV-SDTGEYFVENKQVSAFTNSEELFFIPDAK--NIFPFLLETKLREQSATFIAG-ENYLNQVSVHDNLITGQNPWSVWEVAEETIK---------- +----KILAVVTSTD-KM-AQDKPTGYEHTELARAYWVFIANGFEVDIASPKGG-------KPPVVIDGEDMGAYDYNDKTIQAQVANTLLLSQIDPNDYQAVYFVGGKGTMFDFPDNNDVKRITKALYQNNKVVSAVCHGPAALVNVT-LDDGSHLLEGKTVSGFTNEEELFLIPDAK--TLFPFLLENKLVARGAIFQPG-PQYLEQVVQDGKLITGQNPWSVWTLAERVIA---------- +----RILAVVSSAG-VF-PGEKRAGFELTELARAYYTFIANGYEVDIASPLGG-------PPPMRVDDEDMGVADHNDAQARARLAASLPLEQVDATRYAAVYFVGGKGAMFDFPGNAAIARLVRHVHGAGGVIGAVCHGPAALLEVT-LDDGTPLLRGRRVTGFSNAEELFLMKDAR--QRFDTLLQDALAQRGARFVEG-GLYLDNTVVDGRLVTGQNPWSTWSVAEAMVR---------- +----KILAVVTSTD-VM-DTGQKTGYELTELARAYYVFEANGFEVDIASPKGG-------KPPVVIDDDDMGKFDFNDTVAQVKVDNSIAMADVNTSQYQAVYFVGGKGAMFDFPENASIKSLVSEYYQSGKVVGAVCHGPAALVNVT-LDDGSALLANKIVSSFTNDEELLLIPNAK--DIFPFLLQNKLTEQGANFDVG-HVYLANMAQDGNLVTGQNPWSVWLVAEAMIE---------- +----KVLAVVTSID-IM-GAGKDTGYELTELARAYYVFEANGFEVDIASPKGG-------KPPVVLDDDDMGKFDFNDTLAQTKVDNSIAMAEVDTREYQAVYFVGGKGAMFDFPDNVAIKSLVSDYYQSGKVIGAVCHGPAALVNVT-LDDGTALLANKTVASFTNDEELLLIPDAK--EVFPFLLQNKLIEQGANFDAG-HVYLDNTVQDGNLITGQNPWSVWSVAESMIA---------- +----KILAVVTSCS-EM-GEKKPTGYELTELSRAYYVFVANGFEVDVASPAGG-------KPSVIIDGDDVGEFDFNDSEAQSKVNNTIAMKDVVPDDYVAVYFVGGKGTMFDFPQNQHIQSLVREYYEEGKVIGAVCHGPAAFVNVT-LRDGSQLLDGKQVSSFTNKEELLLIKDAR--SIFPFLLQDKLIENGAIFNEG-HMYLEKISEDGNLITGQNPWSTWAVAEAVVN---------- +----KILAVVTSTD-TM-GTGKGTGYELTELARAYYVFKANGFDVDIASPLGG-------KPPVVLDDDDMGIFDYNDSIAQSKTNNSLLLKDVKPEIYEAVYFVGGKGAMFDFPNNRFIHALIQDFHKNNKVIGAVCHGPAAFVNIT-LDDGQSFLKNKQVSSFTNKEELLLIPDAA--SVFPFLLQDELISQGAVFNEG-IMYLEKISYDNNLITGQNPWSVWAMAEAMVK---------- +----KILAVVTSCG-VM-GDGKPTGYELTELSRAYYVFMANGFEVDIASPLGG-------KPPVVIDDEDMGVYDYNDTIAQIKVDHTIAIKDVTPDDYQAVYFVGGKGTMFDFPDNKYIQSLVRQYYDSGKVIGAVCHGPAALINVT-LNGGQHLVANRKISGFTNEEELFLIPDAP--DIFPFLLQDKLVEKGARFDRG-SMYLENVVQDGSLVTGQNPWSTWKVAGQMIE---------- +----RILAVVTSAG-SS-AIGKNLGYELTELSRAYYVLQANGFEVDVASTQGG-------KPKMVIDTDDMGQHDYNDAIAQTKITNTIPINQVSASQYDAIYFVGGKGALFDFPNNTAIQTLVRDMYQQGKVIAAICHGPAALVNVK-LANGNFLLADKQVTSFTNEEELFLMPNAA--KVFPFLLESELKQRGARFYAG-PLYLDNLITDDKLITGQNPWSVWATANAIVK---------- +----KILAIVTSAN-TM-GSDKSTGYELTELSRAYYVFQANGFEVDIASPLGG-------EPPVVIDDDDMGKYDFNDSIAQHKVKHTIMVKDITPEAYEAVFFAGGKGAMFDFPENKAIQDIVRYLYQSNKVIGAVCHGPAALVNVT-LDNGRPLLENKKVSSFTNDEELLLIPDAE--TIFPFFLQDKLTAQGARFSKG-AMYLEHISRDQNLVTGQNPWSTWRLAETMIS---------- +------------------------------------KVEAAGYQVDYVSPRGGYTPDPHSLAM--ADDTDWTWYQTK--EFMNRLGATLKPSEVKPDDYVAIYFAGGHGVIWDFPDNEELQAISRRIYESGGYVSSVCHGAAGLLNIKM-SDGTLLVKGKKVTGFSNEEEKLAELDKYV----PFLTETELVNRGAIYTRRM-SLGQHML----LKTGDSL---------------------- +-------------------------------------MHTAGYEIDFVSPQGGKAPDAFNMNDSIN-----KKFWDN--DVYRSIENTKKPSEVNPEDYVAIHYAGGHGAMWDFADNTEIAEIAKQIYENNGVVSAVCHGPAGIVNIKL-SNGLYLVDGKKVNAFTNEEEVKVKLENVV----PFLLEDQLIAHGAIFEKSA-PFTEHVVTDQRLVTGQNS---------------------- +------------------------------------ELIQAGYVLDYVSPRGGYVPDPRSLKNAYVNEEVFALYGSE--DFQNRLANSLKPSDINASDYLAVYYTGGHGVVWDFPDNKALQAISREIYEQGGYVTSVCHGLAGLLNIKT-SDGSYLISGKTLTGFTETEEILSGKKRLV----PFGTEKEARNRGAKFVKKR-AFSSFAVQDGHLITGQNA---------------------- +------------------------------------VVTKAGFQVDYISPEGGYVPDPRSLKGTYIKPSDLTLYQSK--DFQDRLSNTMTAKDVNPDDYLGIYYTGGHGVLWDFPNNYALQKLTSHIFTYGGYVMSVCHGLAGLLNVKD-AADDYLLDGKKVTGFTDQEELLSGKQSYI----NYSVEKMAKERGAEFQKTI-PYTSFAIQDKHLITGQNA---------------------- +----KILMVMTNH-DRYPSRAERTGLWLAELTHVYDVLEAAGYAIDFASPNGGAIPDPRSLGWPHADAAAKARL--NDPSFMARLQSTQAVADLDPTVYRAIFYTGGHGTIWDFRGNADLKRVAESIYRSGGIVSAVCHGLA---GLLDLQAGKPLLEGRRVTGFSNLEESLSGVKDQVPYLQSE-----MEARGARYEKSLLPFGSFALTDGRLITGQNPRSSKALAQAL------------ +----KILMVMTNH-DRYPSRTERTGLWLAELTHVYDALTEAGYAIDFASPNGGPVPDPRSLGWPHADAAAKARL--NDPAFMALLQSTRAVADIDPGAYRAIFYTGGHGTIWDFRDNADLNRVAESIYRSGGIVSAVCHGLA---GLLDLKTGRPLLEGRRVTGFSNFEEALSGVKDQVPYLQSE-----MEARGGRYEKAVMPFGSFALTDGRLITGQNPRSSKALAQAL------------ +----KVLLVMTSH-DRYPDRNDGTGLWLAELTHVYDVLTAAGYAVDFVSPKGGAVPDPRSLGWPHADAAVKARL--RDPAFMARLQATRAAADIDPDAYLAIFYTGGHGTMWDFRDNQALKRAAESIYRHGGIVASVCHGAA---GLLELEAGRPLIAGRRVTGFSNLEETLSGVKDQVPYLQSE-----LEARGARYEKSWLPFGSFVLTDGRIVTGQNPGSSKEVARAL------------ +--PKKILFVVTNHE--KLGNTKKAGTYLPEITYPFEVFNQKGYQVDFVSPKGG------MLAINGIANVDETTRHFRDKQRLNELRKTLSPDQVDINQYAGIYYVGGKGTMWDFPDNKKLQKITAKMYESNKVVGAVCHGPSGLLNVK-LSDGSYLLAGKKATGYSNA------EDKIKHILPF-LLEDRLKERGVKYSKAT-KKQKHVVVSDRLVTGQNPASAAGVAEEMI----------- +--SRRVLIVASSKA--FHGDSLPAGTSFEELFSAYDVFTQAGLIVDFVSTQGG------ALNLSYINTSNGEHKKYYQPDYMYALSNTMRPAEVDPSQYAAIYYVGGSNAMYEVAENPTLQRIAMHIYEQQGVVAAVCHGTAGIVNLR-LKNGEYLIKGKQITGYPTAFE---NPDAYFKHFPF-QIQPKVEELGGNFVYGE-R-DSFIKVDSRIVTGQNYQSSQAVASTVL----------- +--KNRILFVTSNQH--TYGNTISAANHFEEIVIAYDVFRKSGYAVDFVSPDGG------AIPVGYVDTSNPTQKEHYDASFMALLKNTLKPEKINASEYQAVYYSGGGAAMFGVAENKRIQNIAGTIYE-GGVVSAICHGTAGIVNLK-NPDGAFIFANKKVTGFPDIFE---DTKEYYKAFPF-SIDKEVSKNGGNFVYSK-KWGNFFIVDGNIITGQDPTATASVAQEVI----------- +--ARKVLLVVSNVH--QYPGTINAGNNFPELAYTYDAFRKAGYAVDFVSPEGG------AVPLEMIVTSDALLKQYYDSDFMWALAHTRPVAEVRADEYAGMAFVGGGAAIVGVPDNKPLQDIALRIYEQGGVIAAICHGTEGIKNLK-LSDGTFLIQGKTLTSFPDAFL---NKEPIYKAYPF-SAEGSIKGHGGIFRHGA-N-GSHVEVDGRLVTGMSWESSVGVAESMI----------- +--PRKVLLVVSNVH--QYPGTVNAGNNFPEIAYTYDVFRKAGYTVDFVSPEGG------AIPLEMIVTSDELLKKHYDSDFMWALAHTKPVSEVRADDYAGMAFVGGGAAIVGIPENKALQDIALRIYEQGGVIAAICHGTEGIKNLK-LRDGTFLIQGKVLTSFPDAFL---NKEPVYKAYPF-SAEASIKRHGGIFRHGA-N-GSHVEVDGRLVTGMSWEASVGVAESMI----------- +--KQQILFIVSNAH--YYGKSIATGNSFAEIVNAYNTFKISGYTVDFVSPEGG------SIPLAYINTSDTLQKQYFDPDFMYAIKNTKKPEEIDSKNYKAVYYVGGGAAMYNVPENKQIQTIALQVYEEKGIISSVCHGTAGIVNLK-TNDGKYLVAGKKISGYPDSFE---KQDEYFKQFPF-LIQKTIEERGGTFKFSK-G-DSHVETDGRIVTGQNFQSSSDVALKII----------- +---KSVLLIVSNAH--YYGDTLNTGNSFSEIVNAYDVFKNAGYTIDFLSPEGG------AVPLAYINTSDEMSKKYYDTDFMNALKNTKSPSEINVSKYKAVQYIGGGGAMFGVPENEAIQNIVMEIYEENGVISSVCHGSAGIVNLK-TKDGKYLVDGKDVSGYPDDFE---NKDPYFKTFPF-LIKETIEKRGGTFHFSE-S-GPHVEVDGRLVTGQNFLSSKLVSLKVI----------- +--KKKILFIVSNAH--YYGNSISTGNSFAEIVNAYDTFVHSGYTVEFVSPKGG------AIPLGYINTSDSLQKQYYNRDFMYALEHTVKPEEIDYTMYKAVHYIGGGSAMYDVPENSAIQRIAMQVYEDNGIISSVCHGTAGIVNLK-TKNGKFLVEGKKISGYPDSFE---KQDEYFKQFPF-LIQKTIEERGGHFKFSK-K-NSYVEQDGRIITGQNFQSSNGVALKII----------- +--ADKILFIVSNAA--HYGNSISTGNSFSELVNAYSTFKSAGYTVDFVSPEGG------TIPLSYIDTSDSLSMSYYNSDFMYALKHTHKPSEIAPQNYKAVHYIGGGAAMYGVPESQEIQKIAMAIYEQNGIISSVCHGTAGIVNLK-TKDGKYLFKNKLVSGYPDSFE---KKDAYFKHFPF-LIQKTLEDRGAVFKFSP-R-NSHVEVDGRLITGQNYLSSRDVALKII----------- +--KKRILFIVSNAH--FYGNSIATGNSFVEIVNAYHTFTTEGYTVDFVSPEGG------SIPLAYINTSDTLQKKYFDQAFMYAMAHTQKPAETDYRNYKAVHYIGGGSAMYQVPENKEIQQIALKVYEDMGIISSVCHGTAGIAHLK-TKDGKYLVNGKRISGYPDHYE---KQTEYFKHFPF-LIQKTIEERGGTFKFSG-R-NGHVEVDGRIITGQNFQSSSGVAKQII----------- +--KKRILFIVSNAH--YYGKSISTGNSFAEIVNAYDTFVNSGYTVDFVSPKGG------EIPLAYINTSDSLQKQYYNQDFMYAIKNTVSPKEIDYKIYKAVHYIGGGSAMYEVPENLDIQRIAMQVYEENGIISSVCHGTAGIVNLK-TKNGKFLVEGKKVSGYPDSFE---KKDEYFKYFPF-LIQKTIEERGGTFEFSK-R-NSYVEQDGRIVTGQNFQSSKGVALKII----------- +--KQNILFIVSNAH--YYGKSIAAGNSFSEIVNAYNTFKTAGFTVDFVSPEGG------SIPLAYINTSDTLQKQYFDPNFMYAIKNTKKPNEIDSKNYKAVHYIGGGSAMYDVPENKEIQTIALKVYEEKGIISSVCHGTAGIVNLK-TNDGKYLVAGKKISGYPDSFE---KQDEYFKYFPF-LIQKTIEERGGIFKFSA-R-NSHVETDGRIVTGQNFQSSSGVALKII----------- +--QNKILFIVSNTS--FHGTSLPTGNSFSEIVNAYDTFKKAGFTVDFVSPKGG------CIPLAYINTSNTLQKKLYNEDFMYALKHTKEPKDIIAKNYKAVHYIGGGSAMYDVPMNKEIQKISMTIYEANGIISSVCHGTAGIVHLK-TKDGKYLVKGNVISGYPEAYE---KEGEYFKQFPF-LIQKTIEDRGGVFKYSP-R-NEHVEVSGNIITGQNYLSSKGVALKII----------- +--KQHILFIVSNAH--YYGKSIATGNSFSEIVNAYNTFKTAGYTVDFVSPEGG------SIPLAYINTSDTLQKQYFDQDFMYALKSTKKPEEIDSKNYKAVHYIGGGSAMYDVPENKEIQTIALKVYEEKGIISSVCHGTAGIVNLK-TKDGNYLVAGKKISGYPDSFE---KQDEYYKYFPF-LIQKTIEERGGVFKFSA-R-NAHVETDGRIVTGQNFQSSSGVALKII----------- +--HKKVLFIVSNAH--YYGTSLTTGNSFSEIVIAYDTFINAGFTVDFVSPDGG------SIPLAYINTSHALHKKYYDMDLMYALKNTKTPEMINPESYSAVQYIGGGSAMFGVPEDKNIQKMVMTIYEKGGIVSSICHGTAGIVYLK-TSDGQYLVKGKAVNGYPEDYE---RKEAYFKQFPF-LIRETIEQHGGNFKYSP-R-NVHVEVDGRIITGQNHLSSKAVSEKII----------- +--PRQVVLAVSNVD--IMPGTLSAGNSFLELVRAYAGFREAGYGVQFVSPEGG------AVPLAYIDTSNPEHKAGFDADLMWALANTRRPDEVTASDYSALMYIGGSAAMYGVAEHPGMQWLAVRIYEQGGIVSAVCHGSAGLVNLT-LSDGSALVSGRRVTGYPDAYE---DMSAYYKTYPF-SIEQRLRGSKAQFSHGA-R-GPHVEVDGRLITGMNWESTRGVVAAII----------- +--QKRVLFIASSAD--QHGKSLPTGTSFSELVEAYEVFIDSGYQVDVVSTQGG------KLPLAYINTSDLKHKQYYNQDFMYLLANTLSPEQVDASQYLAVHYVGGGNAMYQVAENKTLQAIAMQVYEKHGIVSSVCHGTAGIVNLK-LSNGKYLVSGRKISGYPTEFE---KTDNYYQQFPF-DIEETIKQRGGKFFYGE-R-NPYVQIDGRLITGTNYQSSKGVALAMV----------- +--YKKILFIASSAS--FHGDSLPAGTSFSELVYAYDTFIKAGYEVDFMSTRGG------ALSLSYINTSMPIHKHYYDPEFMYAIGHSLTPEQVDASQYHAVHYVGGSNAMYEVAEHPQIQAIAMQVYEQNGIISAVCHGTAGIVNLK-LKSGEYLLANKRVSGYPESFE---RQDAYFKEFPF-LIGEQVKARGGVFLYGE-R-NAFVEVDGRLITGQNYLSSVAVAQAMI----------- +--YKKILFIASSAS--FHGDTLPAGTSFSELVYAYDTFIKAGYMVDFMSTQGG------ALSLAYVNTSVPIHKQYYDPEFMYAIGHSLAPEQVDASQYHAVHYVGGSNAMYEVAEHPQIQAIAMAVYEQNGIISAVCHGTAGIVNLK-LKSGVYLVANKRVSGYPESFE---RQGPYLKAFPF-FIGERVKARGGEFLYGE-R-NPFVEIDGRLITGQNYLSSVAVAKAMI----------- +--QKRVLFIVSSAD--FHGDSLATGTSFSELVEAYDVFINAGYQVDVVSSKGG------TLPLAYINTSDKTHRQYYNQDFMYKLAYTLAPEQVDPEKYLAVHYVGGGNAMYQVAENKNIQAISMHVYEQKGIISAVCHGTAGIVNLK-LASGEYLVAGRKITGYPTAFE---KTDAYYQQFPF-AIDNLIKQRGGIFNYGQ-R-NSFIEVDGRIITGTNYQSSREVAQAMI----------- +--QKRVLFITSSAD--HHGESLPTGVSFSELVEAYEVFINAGYQVDVVSTLGG------KLPLAYINTSNEKHKKFYNQDFMYLLANTLAPEQVDASQYLAVHYVGGGNAMYQVAENKTLQAVTMAVYEKNGIVSSVCHGTAGIINLK-LSNGEYLVAGRKVSGYPTAFE---KIDAYYQQFPF-DIEKTITQRGGKFSYGE-R-NSYVQIDGRIITGTNYQSSKAVALAMV----------- +--RDRVLFVLSSAK--FHGASLPAGVSFGEVVEAWDAFRAAGLTVDFVSPEGN------AAPINVT--EAGEFRSRYDADLMYALEHTHAPSQIDPARYRAVYFVGGSNAIYGVPENSRLQDIARHVYERGGVVSAVCHGTAGLVNLK-LSDGSYLIGGKRVSGYPEEFE---RQDAYFKEFPF-LIRKTVESRGGTFLTSA-R-DGYVVVDGRLVTGQNYLSAKQVAQAVV----------- +---KKVLFVVT-NHTQLGNTGETTGYFLSEVTHPLEVLTEAGYKVDFVSPKGGSTT-AYGVKDDPI---NKKYWES--TDYQKQLAHTLAPSQVKAKDYAAIFYAGGHGTMWDFASSEALAKIAQQIYEKGGVVAAVCHGPSGLVNIK-LSNGKYLVSGKTLSPFTNEEEEAVKLSQVVP----YSLENKLKERGAI-IDKAGLWQDKVSVDNRVITGQNPQSAKSVGEAI------------ +-----------------------------------------------------------------------------DEQAKRALRLPPRCRSISPRSTRCTRVATVRCGIWRTIPPRSRSSWIATPWGGRYVMPPVCCTPS------KKHDGTLFVTDRSVTGFTDGEEEAAGLTGVVP----FLVEDSLKQAGARYSKG-PDGDSYVVTDKTLVTGQNPASSAATAQRLLDL--------- +-----------------------------------------------------------------------------DTEAQAALASTVLLGEVDPYDFDAVFYPGGHGPLWDLAEDRDSKILIEAMYAANKPVAAVCHAPGVFK-NVVAPDGQPLVKGKKVTGFTNSEEDAVGLTQVVP----FLVEDMLKAKGGEYSKA-ADWAVYVVEDGHLITGQNPASSEAVAEALLKR--------- +-----------------------------------------------------------------------------ASEAQSALASTLSLQSISLDDFDAVFYPGGHGPLWDLAEDKSSIDLLASALASNKPVALVCHAPGVLR-HVKNPDGTPVVKGKKVTGFKNSEEAAVGLLEIVP----FLVEDELISRGGQYSSA-SDWASYVVKDGNLITGQNPASSAEAARQLLLL--------- +-----------------------------------------------------------------------------TPAAQEVLANTLRLAEVKMDGLDAIFYPGGHGPMWDLADDENSIVLIEDFYNAGKPVAAVCHGPAVLH-RVT-YQGEPIIKGKRVTGFTNSEEEAVELTEVVP----FLVEDELKRLGGRFEKA-ADWADFTVVDGRLITGQNPSSSTSAAKELLKL--------- +-----------------------------------------------------------------------------DAAAKAQLAATVRLDSISQADFDTVFYPGGHGPLWDLAEDANSIALIESFVAAGKPVALVCHAPGVLR-HVTAPNGKPLVDGKKVTGFANSEEAAVGLTDVVP----FLVEDELKAKGGIYSKG-DDWAPYVVTDGLLITGQNPASSSSAAATLMKH--------- +--MKKILMVLTSVS-ELGDTGEKTGYNVAEAAHPWKVFKDSGHFVDFASIKGGQPPSDEVDTDDPIQ----VAFTT-DETTRAGLYNTARVDVIDPGQYDAVYLVGGHGTMWDFPDSEGLQRLVASVYDAGGLVGAVCHGPAGLLNV-ELENGFRLVQGRDVAAFTNEEEVAAGKDKVIPFFLADRLE----EQGARHV-TAGVFEEKVAVDDRLVTGQNPASAAGVAKEME----------- +----AALIVLTSQD-KLGDTGRSTGAYASEVADAWRVFTKAGYRIDVVSVRGGVAPLEA------VDGH-REFLEDT--VVSARLDATATPGAVDPTQYAVVFFAGGHGAVWDFPDDKDLAEMTARCYDNGAVVAAVCHGGAALINVVG-ADGTPVIAGKRLAAFTNDEERAVGMIDIVPF-LL---ADALVKRGAVHEAPS--FLPHVVIDGRLVTGQNPASATGVAEA------------- +----------------------------------------------------------------------------------------------------------------------------------WAYLESLCHGGAIFPGIIDSSTGKSVIAGRKVTGFTTRGEEEEGVLDTIKSWSRPTIESSAAACGANYVSPAGPWDAFTVTDGDIVTSANPASAHVTAEAAV----------- +------------------------------------------------------------------------------------------PKVL-VVLTSQSKMNNGHPTGWYLPE--------------------FAHPYYD--LVNNGVEITPLLEGREATGFSNSEEEAVKLTSAMPVLL----EDEIKRVGGKYVK-ADDWAEKLAVDGQVITGQNPASAHAVGKAI------------ +--------------------------------------------------------------------------------------------------------------MWDFPENAEIQAIARSIYKAGGYLTSVCHGIAG--LLNLKEQGHYLIAGKKITGFTTSEEIIAGKKKVIPFLN----QTLAAAHGANFQK-KRFYKSYALQDGQFITGQNPFSVRAVAKLL------------ +--------------------------------------------------------------------------------------------------------------------MAEVIYQ------QGGYVTSVCHGIAG--LLNLRPNGEYLLANRQVTGFTTGEEVLAGKRWQVPFLN----QTEVTRRGGHFVK-RRPYAAFAVQDGRLITGQNPFSAQAVATKL------------ +------------------------------------------------------------------------------------------PANVKSKDYTAIYFTGGHGVMWDFPENSALQKIASDIYESNGYVLSVCHGIAG--LFNIRANNDYLIANKKLTGFTKTEELLAMKSKVVPFDN----EEMTVRRKGYFIK-KRFFKSHVVKDGHLITGQNPYSTRELARTF------------ +--------------------------------------------------------------------------------------------------------------MWDFPDNKEIQEIALSSYENNGYILSVCHGIAG--LLNIKREGNFLISGKKITGFTKTEELLAGKMKIVPFFN----QKMAEEREAIFQK-KRFYKEFALKDGRIITGQNPFFVRAVAKLY------------ +------------------------------------------------------------------------------------------LEEIEPDEYAAIYFTGGHGVMWDFPDNPQLQAITRSLYEQGKYLTSVCHGIAG--LLNVKASGNYLIADKTITGFTTAEEILAMKKAVVPFLN----ETIAKEHGATFAK-KRPYKEFAYQDGLIITGQNPFSVRAVAKLL------------ +----------VTNHTSLGNTGKKTGWVSKTKLTQYRSLKKNKKIIKFVSPKGGLAAVDPGSVKSYAKDEECVKFYKDMCDSNGNLKT-VAIGELNPLGYQVEVHAGGHGTMWDFPNDKHLQRAGEMIYRNGGILASICHGPAGILNLKDSK-GRYLIQGKHVTGFSNAEEAADSVMPYL-------LEDELVKRGAKYSKANQLWACHVVSDERIITGQNPKSGHL----------------- +------------------DQDTPTGWYLPEAAHPYYEFKAAGFDIHFGSPKGGLPPVDPSIEA--TKDDDECQFNTD-EAIQAQLAASIKLEDAVENSYDVIFVVGGFGVMWDLPEDAALQALYRKTYEAGGVAAAVCHGPAALVNVT-LSDGSLLVAGKAVTGFSNAEEHAVERYDVVP----FTCENKLAEQGGKYSAA-EPWNSNVASDSRVVTGQNPQSARDTAKAIIE---------- +--AKKALLIVTS-HTELGDTGKKTGFWFDELATPFWGFYDAGYEITIASIQGGALPDPLSKQGEFVSPEVA-RFIQSKVAMS-LLENTPCVETIRTGGYTTLFLCGGHGTLWDFKESKGLARIVSEFYADNKLIGSVCHGPTGLLSA-KKPNGSPLVEGLKLTSFTDAEEQLTPPQ-YIQALPY-HIEDELVKSGARFDAE-QPNASFVVCEKGLITGQNPASVK------------------ +--------------------------------------------------------------------------------------------------------------------------MVSQFYAAEKLIGSVCHGPTGLLSA-KKPDGSPLVEGLKLTSFSDEEETLTPIQ-YTEALPY-HIQDALVEQGALYQCE-QPNAQFTVWEQGLITGQNPSSVA------------------ +--VKKALLIVTS-HTELGDTGKKTGFWFDELATPFWGFYDAGYEVTIASIKGGALPDPLSAQGEFVSPAVD-RFMQSTIAMN-QLDNTPSVDTIRTGRFTTLFLCGGHGTLWDFKQSNGLARIVSEFYADKKLIGSVCHGPTGFLSA-KKPDGSAFANGLKLTSFTDAEEQLTPPE-YLQALPY-HIEDELIKVGAKFEAK-QPNASFVVCEDGLITGQNPASVK------------------ +--VNKALLVVTS-HTQLGDTGQKTGFWFNEMATPFWRFYNAGYEVTIASIQGGAQADPLSCSGEFVTQQVK-QFQQSDYAMS-LLKNTVCIDDVDSSVFTTIFLCGGHGTLWDFRQSSGLARVVSEFYADKKLIGSVCHGPTGLLSA-KKTDGSPLVEGLKLTGFSDAEEKLTPPE-YIKALPY-HLEDELVKEGAAYQCE-KPSAKFVVTEKGLISGQNPDSVD------------------ +-------LFVTS-NQEFYGNTIPAANHFQEIIVPYDAFIKAGYEVDFISPKGGLGYMSDSLQKKYLY----------NGWFMNKLEHTMKPTEIIADNYLAIFYSGGGAAMFGVAEDITIQKIAGKIYNKNGVIAAICHGTAGIAYLKN-ENGNSLYAGKKITGYPDIFENK---DAYYKAFPFSIDKEISKNKNFKYSEKAG--DGFYIVDGRFVTGQDPSSAL------------------ +-------------------------------------------------------------------------------------------------------------------------------------------------------DGTPIVKGKTVTSFTDEEEREVGLDVHMP----FLLESTLRLRGANFVRGE-KWTDFSVRDGNLITGQNPQSSRSTAEKVVA---------- +------------------------------------------------------------------------------------------------------------------------------------------------------------MKGKHVTGFSAAEEAGYAK-DDVP----FELEDLLKERGAGYSAVD-PWQPHSITDGRLVTGQNPASAQGVAEKVIA---------- +---KKVLIVLTSADRI-PKLDRPTGWYLPELAHPYLVLAPE-AEIAVASPKGGAAPLDPSSVDAYKSDEASARFRDHRSVWEA---TTPLAEYVRAGDFDAVFYPGGHGPMLDLAADADSVRLVEEFYAAGKPVAAVCHGPIALRDARSSEGGEPILRGRRVTGFSNAEEEQVQLSA----AMPFLLEDELKRVGARYEAAPEPWGEKVVVDGQIITGQNPASAKGV---------------- +--SRKALILVTSYNGPFYDDGDNTGVYYPEVYGLFRVLQSNGFDVEFASDTGEYGFDCKSVQESSTTREALNVLDDPKSTLVAKLKTISRLSRLDPDDYDAIIVSGGYGCYFNYSHCKDGQEFMRAMFRKNKVIATVAEGVLLLTYT-TRDDGHTLCWNRRITSCTWRDSIQNGVQDI----------------------------------------------------------------- +MSPK-VLF-VLSSHDQMGNTGKPTGWYLPEMAHPYYKLEGE-ADITVVSPAGGKAPLDPASVEMFKEDAEAQQFLKEKSALWKLSDYIGKASQFD-----AIFYVGGHGPMFDLATDEKSHQLIREFYEAGKVVSAVCHGPAAFAKVK-LSDGSYLVNGAEVTGFSNTEEDQVQLSSVM----PFMLEDELKKNGGKYVKADEPWGAKVVKNGKLLTGQNPNSAGPI---------------- +---AKVLFVVTSCDV-KGDTGIPTGFNLSEVTHPLEKLEESGVIVNIASIKGGKAPLDG--LEDFNDPVNAKYW--ADTDFRNALENTLKLDDVKAGDYDAIFFAGGHGTMWDFADSPAVLRLVPEFYESGKIVSAVCHGPAALVNVK-LSNGSYLVAGKNVAAFTNGEE------EEVQSTNVVLLEDALIGHGANYKHSS-NWSNNIAIDGKLITGQNPQSAASVGLAI------------ +--GKKALIVCTN--TDQMSNGKPTGVFASEMTVPYYIWNDAGMSVDLASPLGGVIPDPQSYRPVVRTHHD-DRS-LKDGHLQKKLSESLAIGDINIDQYDVVYFAGGWGAAFDLGFSEAVGEKVTEANQKGKILGGVCHGPLGFLKAKG-LNGDPLVKGRRVTGVTDKQVRDLRITATPH-----HPETELRKLEADFRCTHDPFANWWEVDGNIVTGQNQNAAPMVA--------------- +--DFRALIVCTN--HSWLDVAKPTGVFSSEMTVPYYLFTDAGIEVDLASPLGGEIADPMSLRAVTRSHHD-DRF-LVDDLLKEKVRKSISMSDIDVEIYDVIYFAGGWGASFDLGFSDIVGQKVTEANAKGTILSGVCHGPLGFLRASN-LQGRPLVEGRRITGVTDKQVLELGIDATPH-----HPETELRKLGADFKCSHDPFANHWEVDENLVTGQNQNAAPMVA--------------- +--GRRALVIATN--HATLGDGTPTGVFSSELTVPYYYFEDAGMYVDVASPLGGVVPDPMSLKPVLRTTAD-DRY-LGDDILASKLQDSLAIADVDVTDYDLVYLAGGWGAAFDLGDSEPLAEQMTAAAAAGLVIGGVCHGPLGLVNATA-ADGRPLVEGRKVSAVTDKQVRELRITSTPR-----HPETELRKRGALFESATDPFANHWVVDGDLVTGQNQNAAPMVA--------------- +--GRKALIVCTN--HGWLDVGKPTGLFASEMTVPYYAFQDAGMNVDLASPKGGLIPDPLSLKPVLRSESD-DRF-LADDELRAQVNDSLAIGDLDVADYDLVFLAGGWGAAFDFGFSKPLAEAMTTANALGKVIGGVCHGPLGLINAKA-ADGTPLVTGRRVSAVTDKQVSELGITSTPH-----HPETELRRVGARFESETDPLSNHWVVDGNLVTGQNQNAGPMVA--------------- +--GKRALVVATN--VAWLDVAKPTGVFASEMTVPYYAFADAGMEVDVASPSGGMVADPKSLRPVIRSADD-DRF-LADDDFKAKVADSKPIADLDMSDYDIVFLAGGWGAAFDFGFSDSLARKMTEANAADVVLGGVCHGPLGLVNAKA-TDGTPLVAGRKVSAVTDKQVRELGIEATPH-----HPERELRRAGANFESATDPLANHWVVDGNLVTGQNQNAGPMVA--------------- +--GLKALIVCTN--HAWLDVGKPTGLFASEMTVPYYLFSDAGIEVDLASPKGGEIADPISLRPIPRSEHD-DRF-LADTELKTKVRNSISISDVDVDDYDVIFFAGGWGAAFDLGFSDTIGEKVTEANTKNLVLGGVCHGPLGFLKAKN-ADGEPLVKGRRVTAVTDKQVKELGIETTPH-----HPEKELRELGADFQCTHDPLANHWEVDGNIVTGQNQNAGPMVA--------------- +--GLRALVVCTN--HATLDIGKATGVYSSEMTAPYYAFLDAGMQVDLASPLGGIIPDPQSLVPVLRCAAD-DRF-LADQELRSKVADSLPIGTLDMSEYDLVFLAGGWGAAFDFGESADLAEKVSEAAAAGLVLGGVCHGPLGLCNAST-PDGRPLVEGRRVSAVTDKQVRELGIESTPQ-----HPETELRKRGALFESSTDPFANHWVVDGNLVTGQNQNAGPMVA--------------- +--MSRILMILTS-HDQLGDTGRKTGFWLEEFAAPYYVFCDAGHDVTLASPRGGQPPIDPSLPQ--MQTDATRRFD-VDEQAKRALTTTTPLSEVDIATFDAVFYPGGHGPLWDLVDDPTSQQIILDSDAVGRPLGLVCHAPGVLHTVK-KHDGTLFVTDRSVTGFTDGEEEAAGLTGVV----PFLVENSLKQAGARYSK--GPGDSYVVTDNTLVTGQNPASSAATAQRLLDL--------- +------ILFVTS-NQEFYGNSKITAANFEEIVIPYHLFVKAGYSVDLISPKGG------AIPIGYINSSDSIQKKYLDAFFMDKLEHTSKPLDINTDDYSAVLYTGGGAAMFGVAEDQTIQNITRKIYERNGVVGAICHGTAGLVYLKN-DAGKSLYKDKKITGFPNKFENQKA--AYYKTFPF-VIDQAIKKNGGNFVYSDQGWDSFTIVDGRFVTGQDPSSASKM---------------- +MSPRPKLVVLTS-HAKLGNLDKETGWYLPEFAHPYWKLEPH---VDLASPAGGEAPLDPSSVEMFKNDEESQRFLKEKQDLWKKTEKLSDFKGKTGEFAGIYY-PGGHGPMFDLASDPTSIELARDFYESGKVVSAVCHGPAALVNVK-LSDGSYLIAGQPVTGFSNVEEDQVGLSSAMP-FLLE--TDLQKNSGGKFEKADEPWGVKVVVGGKLLTGQNPASAGPL---------------- +-------------------------------------------GPHCATPDGKATLDQLSLGISMPKDVKDYLDSI-----ADVLAHPASLDSVDPNEFDLVFYPGGHGPMEDLAYDKTSGELLTHRLASGKPLALLCHAPAAVLAAT-NPDGTSAFAGYRMTGLSNREEL------LNRFAKKAWLLEDKLKEVGVEYKGLIPLRPHVVIYRNLYTGQNPQSSEKLATQLV----------- +-------------------------------------------EITVATPTGEPVVDDMSLDPD-V-GRVSTVIDS-----DERLDDPIALADAVADDYDAVFFPGGHGVAWDVTQDHHARELFSEAVAGEGKALVVCHAVGLL-AFTRDADGEFLAADRTVTGFPNAWEEGIVQELLPDGRKLPWVEDEVRAVGANWDAELD--ADTSQVDGDLITGRGPESSHAAARTLL----------- +-------------------------------------------DVTVATPSGSPVVDERSLDPE-G-GELREVDET-----HPGLNDPEPIATVDAEGYDAVVFPGGHGTAWDVNQDRHARQLLLDAVAGESVALVVCHAVGIL-AFTREADGTPLVEGRSITGFPNEWEADIVHDVMPDGRKLPWVEDEVVLAGAEFDAELD--ADTSTVDGDLITARGPGSSADAAATLL----------- +-------------------------------------------DVTVATPTGAPVVDERSADPE-V-GWVRDVDDT-----HPELNDPIRLARAEADGYDAVVFPGGHGTVWDVNQDRHARQLLLEAVAGEGTALVVCHAVGIL-AFTREADGSFLVSDRDVTGFPNAWEEGIVDDC-FGGRKLPWVEDEVKAAGGNFDPELD--ADTSAVDGDLITARGPGSSAAAAETLL----------- +-------------------------------------------ETTVATPTGAPVVDEASLDPE-I-GELRAIDED-----HPKLNDPVPVAGEDADDYDAVVFPGGHGTCWDINQDADARRLLVDAVSGDGTALVVCHAVGLL-AFARTDDGKPLVAGRSVTGFPNAWEADLVHDRLPDGRKLPWVEDEVKAVGGEWDAELD--AETSTVDGDLITARGPGSSAAAAETLL----------- +-------------------------------------------DITVATPTGDVVVDERSVDPD-V-GHVVEVHET-----DERLQNPERLAAVDAREYDAVVFPGGHGTAWDVNQDRHARQALLQAVAGDSKALVVCHAVGIL-AFTREADGSYLVDGRDVTGFPNEWEEDIVADLLPDGRKLPWVEDEVKAVGGNWDAELD--SETSTIDGDLITARGPGSSAAGAQTLL----------- +-------------------------------------------EITVSTPSGKPKVDERSIDPD-V-GHVREVHEN-----DERLNDPIPTAQAEAEGYDAVVFPGGHGTAWDVNQDSDARRLLREAVAGDGKALVVCHAVGIL-AFARDRQGAFIVNGRNITGFPNEWEEGIVNDLMPSGRKLPWVEDEVKAAGANWDAELD--ADTSTVDGDLLTARGPESSSAAAETLL----------- +-------------------------------------------EITVATPSGNPKIDERSIDPE-V-GHIQEVHET-----DERLNDPIPTAQADAEGYDVVVFPGGHGTEWDVNQDHDARRLLRDAVEGDGKALVVCHAVGIL-AFTRDSHGAFLVNGRDVTGFPNEWEEGIVNDLMPSGRKLPWVEDEVEAAGGNWDAELE--QDTSTVDGDLLTARGPESSSAAAQTLL----------- +-------------------------------------------DVTVATPSGNPVVDERSLDPD-V-GRLRDIHES-----DERLNDPEPIAQIDATEYDAVVFPGGHGTEWDVNQDVHARQALVSAVAGDGKALVVCHAVGIL-GFTREADGSPLVQDRDVTGFPNEWEEDIVNDCL-DGRKLPWVEDEVKAAGGNWDAELD--QDTSTVDGDLVTARGPGSSSAAAETLL----------- +-------------------------------------------DVTVATPTGSPVVDERSLDPD-L-GRLREIHET-----DERLNDPIALADAEPGSYDAVVFPGGHGTVWDINQDRHARAALRTAVEGEGKALVVCHAAGLL-AFTRDSDGEILAAGRDVTGFPNAWEEGIVQDLF-EGRKLPWVEDEVTAVGANWDAELD--ADTSTVDGDLVTARGPGSSAAAATTLL----------- +-------------------------------------------EITVATPSGSPVIDETSLDPE-V-GWVREVHET-----DERLNDPEALAAVEAAGFDAVVFPGGHGTVWDVNQDRDARRILAETVEAGRKALVVCHAVGIL-AFTRESDGSFLVEDRDVTGFPNEWEADTVHDVMPDGRKLPWVEEEVVAAGGNWNAELD--ADTSTVDGDLLTARGPDSSAEAARTLL----------- +-------------------------------------------DITVATPSGSAVIDDRSVDPD-V-GHVEEIHES-----DDRLNNPIALADAVPDAYDAVVFPGGHGTEWDITQDRHARAALRTAVKDGSKALVVCHAVGIL-AFTRDADGEFLVAGRNVTGFPNDWEDGIVQHRMPDGRKLPWVEDEVTAAGGNWDADLD--AHTSTVDGDLITARGPPSSHAAALALL----------- +-------------------------------------------DVTVATPSGGPVLDERSVDTA-V-DWVQEVHEN-----DERLNDPEPLAAQTAAEYDTVVFPGGHGAEWDVNQDVDARRLLRNAVAGEGTALVVCHTIGIL-AWTRTDDGDFLAEGRSITGFPNEWEEGIVHDRLPDGRKLPWVEDEVVAVGADWDAELD--SETSTVDGDLVTARGPGSSAAAADRLL----------- +-------------------------------------------EVTVATPTGNPVIDERSIDPE-V-GRVTSVAES-----DDRLNDPIALADADAQEYDAVVFPGGHGAEWDVTQDVHARDALRTAVEGEGTALVVCHAVGIL-AFTRDADGEFLVDGRSVTGFPNAWEEGIVQDLLPDGRKLPWVEDEVVAAGGVWDAELD--ADTSTVDGDLVTARGPPSSHAAAVTLL----------- +-------------------------------------------DITVATPTGEPVLDERSVDPE-V-GHVREVHET-----DERLNNPIPLAQADAGDYDTVVFPGGHGAEWDITQDVHARELLRESVADDGKALVVCHTVGIL-AFTRDGDGEFLVDGRSVTGFPNAWEEGIVNDLLPDGRKLPWVEDEVKAAGADWDAELD--ADTSTVDGDLITARGPPSSAAAARTLL----------- +-------------------------------------------EITVATPTGGAEPDERSVDPD-V-GHVTEVAKN-----DERLRNPVQITEVSAADFDAVVFPGGHGTEWDVNQDRHARTLLRDAVVGEGKALVVCHAAGLL-AFTRDADGEFLVDGRSVTGFPNDWEEGIVQDLMPDGRKLPWVEDEVKAAGGDWDAELD--QDTSRVDGDLVTARGPSSSSRAAQTLL----------- +-------------------------------------------DVTVATPTGEKVVDERSVDPG-V-GAVLEVHEN-----DDRLANPEPIATVDATDYDVVVFPGGHGTAWDINQDRHARQALLSAVGGDGKALVVCHAVGLL-GFTREADGGFLVEDREVTGFPNEWEEGIVNDLMPDGRKLPWVEDEVKAAGGVWDAELD--KDASTVDGDLITARGPGSSHAAAETLL----------- +-------------------------------------------DVTVATPTGAPVVDERSIDPE-V-GRVVEVHEN-----DERLQNPEPIAQVDAREYDAVVFPGGHGTAWDINQDRHARQALLQAVAGDSKALVVCHAVGIL-GFTREADGSFLVEGREVTGFPNEWEEGIVNDLMPDGRKLPWVEDEVKAAGGVWDAELD--SDTSTVDGDLITARGPGSSSAAARTLL----------- +-------------------------------------------DVTVATPTGAQVVDERSVAPD-V-GKVLEVHEN-----DDRLADPVPIATVDATDYDAVVFPGGHGTQWDINQDRHARQALLSAVAGEGKALVVCHAVGIL-AFTREADGRYLVEDREVTGFPNEWEEGIVNDLLPDGRKLPWIEDEVTAVGGAWDAELD--QETSTVDGDLITARGPESSAAAAETLI----------- +-------------------------------------------EITVATPSGGPELDETSADPD-V-GHVREVHEN-----DERLNDPIPTAEADASEYDTVVFPGGHGTEWDVNQDSDARRLLRDAVEGEGKALVVCHAVGLL-AFARDSDGGFIVEGRDVTGFPNEWEEEIVNDVMPTGRKLPWVEDEVEVAGGNWDAELD--QDTSTVDGDLLTARGPGSSSAAAETLL----------- +-------------------------------------------EITVATPSGSPEIDDRSLDPD-V-GHVRDVHEN-----DERLNDPIPTAQADAANYDTVVFPGGHGTEWDVNQDSDARRLLRNTIDGDGKALVVCHALGLL-AFARDGDGEFIVDGRDVTGFPNEWEANIVNDLMPSGRKLPWVEDEVIAAGGNWDAELD--QDTSTVDGDLLTARGPGSSSAAAETLL----------- +-------------------------------------------EITVATPSGGPKLDETSADPD-V-GHVREVHES-----DERLNDPIPVARADGETYDAVVFPGGHGTEWDVNQDSDARRLLREAVEGEGKALVVCHAVGML-GFARDSQGAFIVNGREVTGFPNEWEEEIVNDVMPDGRKLPWVADEVEVAGGEFEPELD--QDTSTVDGDLLTARGPESSSAAADRLL----------- +-------------------------------------------EVTVATPSGGPEIDEQSIDPG-V-GHIQTVHEN-----DERLTDPIPTAQADADDYDAVVFPGGHGTEWDVNQDSDARRLLRDAVAGDGTALVVCHAVGLL-AFARDSHGAFVVNGRDVTGFPNAWETDIVNDCMPSGRKLPWVEDEVKVAGGNWDAELE--SETSTVDGDLLTARGPESSTAAADRLL----------- +-------------------------------------------DVTVATPSGDPVIDERSVDPD-V-GRVRDVHEN-----HAELNDPDPVARASADDYDAVVFPGGHGTAWDINQDRHARALLREAVAGDGTALVVCHAVGLL-AFTRADDGDFLVDGRDVTGFPNEWEEGIVDDRMPGGRKLPWVEDEVKAAGANWDAELD--ADESTVDGDLVTGRGPGSSAAAAQALL----------- +-------------------------------------------EVDVATPTGEPVVDDRSVDPA-V-GQVLECDGS-----DERLQNPVSITTVDAADYDAVVFPGGHGTMWDVNTDRHARDLLADAVAGDGTALVVCHAVGLL-GFTRTNDGEYLADGRDVTGFPNEWEDGIVHDLMDDGRKLPLVEDAVIAAGANWDAELD--ADTSTVDGDLITARGPGSSGAAAETLL----------- +-------------------------------------------EITVATPTGSPVVDERSVDPE-V-GRVREIDDS-----DERLNDPEPIAAVDAADYDAVVFPGGHGTEWDVNQDRDARRLLREHVAGDGKALVVCHAVGIL-GFARDGDRGFLVDGRDVTGFPNAWEEGIVHDRMPDGRKLPWVEDEVVAAGGNWDAELD--ADVSTIDGDLVTARGPESSAAAAETFA----------- +-------------------------------------------EITVATPSGGKVVDERSIDPE-V-GRVREADES-----DPRLQNPVPLATTSADDYDAVVFPGGHGTEWDVNQDKHARALLRDAVETGKKALVVCHAVGLL-AFTRDSDGGFLVDGRSVTGFPNEWEEGIVDDCMPDGRKLPWVEDEVKATGGTWDAELD--AETSQTDGDLLTGRGPGSSHAAAVALL----------- +-------------------------------------------DITVATPSGSPVIDERSIDPD-V-GEVTEIHES-----DERLNDPIPLTTADAADYDLVAIPGGHGTEWDVNQDRHARALLVDAVSGDGKGYVVCHAAGIL-AFAREEDGSPFVEGRDVTGFPNAWEEGIVHDRMPDGRKLPWVEDEVEAVGGNWDAELD--ADTSTVDGDLVTARGPGSSAAGGEKLL----------- +-------------------------------------------EVTVATPSGDPVMDERSADPD-V-GWVREVDET-----DERLNDPSPIASVDAADYDVVVFPGGHGTAWDVNQDRHARDLLANAVAGEGTALVVCHAVGLL-GFAHDDDGRYVVDGRDVTGFPNEWEEGIVQDRMPDGRKLPWVEEEVKAAGGNWDAELD--ADTSTVDGDLVTARGPGSSAAAAETLL----------- +-------------------------------------------DVTVATPSGDPEIDERSVDPD-V-GHVMDVHEN-----DDRLNDPIPVAAADADDYDTVVFPGGHGTEWDINQDNHARTLLAETVAGDGTALVVCHAVGIL-GFTWDESGERIVDGRDVTGFPNEWEEGIVHDRMPDGRKLPWVEDEVRAAGANWDAELD--ADTSTVDGDLVTARGPGSSAAAAETLL----------- +-------------------------------------------DITVATPSGDPVLDERSVDPE-V-GRVREIHET-----DDRLNAPRPTSRVEAVDYDAVVFPGGHGTVWDVNQDRDARRVLRNALSGDEKALVVCHAVGIL-AWVRDEDAGFVVDGREVTGFPNAWEADIVDGRMPDGRKLPWVEEEVVAAGGDWDAELD--SDTSTVDGDLVTARGPESSAAAAQTLL----------- +-------------------------------------------DVTVATPTGDPVVDDRSLDPD-V-GHAREVHET-----DERLNSPVALARVDAADYDAVVFPGGHGTVWDVNQDAHARAALGEAVAGDGVALVVCHAVGIL-AFVGD-DGSRVAAGRSVTGFPNEWEAGIVDDLLPDGRKLPRVEDEVRAAGADWDAELD--ADTSTVDGDLITARGPPSSAEAARTLL----------- +-------------------------------------------DIDIATPSGSKVIDETSLNPDFV-TLAQDLHES-----YEGIQNPEPIASVDSTNYDVVVFPGGHGTMWDINTDSHARALLRDAVEGDGKALVVCHAAGLM-AFTRTSDGDYLVADRDVTGFPNAWEEDLVNDRLPDGRKLPWVEDEVRAAGANWDADPD--AEENIVDGDLITARGPLSSSAAADTLL----------- +-------------------------------------------AVTVATPTGKKVIDDRSIDPD-V-GHLCEIHEN-----DPRLNSPEALGSVDASDYDAVVFPGGHGTEFDITHDRHAREALRTAVEGDGVALVVCHAVGIL-AFTRGSDGSMLVADRNVTGFPNEWEEGIVDDRMPDGRKLPWVEDEVRAAGAEWDAELD--SETSAIDGDLITGRGPGSSSEAAKTLL----------- +-------------------------------------------NITVATPTGGPVIDDRSIDPS-V-GRVCEIHES-----DERLQNPTSLAQIDAADYDVVVYPGGHGTEYDITHDRHARKILRETVSGDGKAMILCHAVGIL-GFTRDATGDFLVSGRSVTGFPNAWEEGIVDDRMPDGRKLPWVEDEVRAAGADWDAELD--QETSRIDGDLITGRGPASSGAAAKTLV----------- +-------------------------------------------TVTVATPTGEQVIDDRSIDPD-V-GHLCDIHEN-----DPRLNNPETLASVDAANYDAVVFPGGHGTEFDITHDQHARRALRTAVEDDGVALVVCHAVGIL-AFTRGSDGSMLVAGRNVTGFPNEWEEGIVDDCMPDGRKLPWVEDEVRAAGAEWDAELD--ADTSTVDGNLITGRGPGSSSEAAKTLL----------- +-------------------------------------------QVVFATPTGGINVDPLSVEVRLFNGNSEKGKEM-----LAILRKPLDLRKARAADYDAIFVAGGHGALFDLNKNIDLHRLILEFDNARKPVGLLCHASSVL-AFM-QKDGKPYLHDRRITGFPTAWEHFVLGRVYKDFLPMPWTGREIDKAARSWFRIMEVLNPWYIQDKNLITGVGPKTGSRLARIVA----------- +-------------------------------------------DVTVATPTGGKVLDEVSVNPD-V-GTVVEAHEN-----DERLANAVPVAGETAEEYDVVVFPGGHGTVWDINQDADARGLLRNAVAGEGTALVVCHAVGLL-GFTRDADGEFLVDGREVTGFPNEWEADLLFDRLPDGRKLPLVTDEVEAAGGEWDAELD--AAESTVDGDLITARGPESSEAAAATLL----------- +-------------------------------------------DITVATPTGGPRIDERSADPE-V-GHVMEVHET-----DERLNDPIPLAKARAGEYDAVVFPGGHGTEWDINQDKHARTLLRNTIEGDGKALVVCHAIAIL-AFTRDSHGAFLVHDRDVTGFPNEWEEGIVDDLMPDGRKLPWVEDEVIAAGGNWDAELE--SETSTVDGDLITARGPGSSSAAGQTLL----------- +-------------------------------------------DVTVATPTGGPRIDERSADPE-V-GHVMEVHET-----DERLNDPIPLAKAQAGEYDAVVFPGGHGTEWDINQDRHARTILRETIEGDGKALVVCHAIAIL-AFTRDSHGAFLVHDRDVTGFPNEWEEGIVEDLMPDGRKLPWVEDEVIAAGGNWDAELD--SETSTVDGDLITARGPGSSSAAGQTLL----------- +-------------------------------------------EITVATPSGSPVIDERSIDPD-V-GHVRQVAEN-----DERLNDPIPVAQADAEGYDAVVFPGGHGTAWDINQDKHARQLLRDAVEG-GKALVVCHAVGML-GFARDSHGAFIVNGRDVTGFPNEWEEGIVQDRMPDGRKLPWTEDEVKAAGGNWDAELD--ADTSTVDGDLITARGPGSSSDAAETLL----------- +---PKILVVLTSADKV-PNTGKQIGWYLPELAHPFHVLNPRA-ELVYATPKGGESPDDDPVCKDFL--------ENHESVWKNTLK----LSDVAASEFDAIFYPGGHGPMVDLVHDEHSKNLLRDFHSQEKVISAVCHGPAAFVNAT-TASGELILKGKQVTGFDDVGEEMFKFTEDM---DFSLERRLGEASGGKYVAEEGPLAEKVVVDGKMITGQNPASSKGVAE-------------- +---IKVLFIVTS-HSEMGNTGVRTGWYLNEVAQPYEVFTKANFQIDFMSPKGGQTPMDP---GSAVEGRDDPQCQKFSSGAINRLNTTMAPSQVNISDYQVIFYPGGHGPMFDLPNNDEIAALTKTAYESGAIVSAVCHGIAGFVP-VRLSSGISIVKGQTLTSLTNSEEAA----------------------------------------------------------------------- +---ARALIITTSV-STLGEDGAATGVFASEMTTPYYEFFDAGMDVDIASIEGKIPIDPMSFAPGLISSYDQRYLAD--EVFLKKTNNSLKIDNIDFTDYDIVFLSGGWGAAYDLGFSEVLGKKITAAYRESIPLGAVCHGSLGFLRAKD-KNGNPLVTGKRITGVTDKQVRELGIEITP-----QHPETELKAAGAIYESNLDILANYIVADGIIITGQNQNAGAEV---------------- +---KQILVVFTS-HTQLIGSDHPTGYYLPEIAHPYYILKDAGYTLVAASPKGGKAPLDQSSVEAFKSDPDSVKFLN-DSTAQDWVSNTKPLSEFSASDFDAIFYPGGHGPCFDLPVDKTSQELIKAFYEAGKPTSAVCHAPAVFTDVK-LSDGSYLVNGKTVTCFTNEEEEQAGLTKAIP----WLVESRLVERGAKFEK-TQPWGEKVVVDGLLISGQNPASAAGVGK-------------- +--QKRALIVLTNISKLPGKDVCFTGFDARAVAHLWSLLVRNFYQIDYCTPEGGPAPDPRSAD------ESKDDPIVQNKTLVDTFQDTMSAKSIESTEYSLIGLVGAHGALIDVAASQDIAKLVTIVYEQNGLICAIGHGLCGALCSQTSLTSFPLLKEKKVTSSTRSEDEQQT------AHVPFFLDERLMALGAWVL-NKGPFEINVCIDYKIVTGQNTASVPAWIE-------------- +--TKSVLVVLTNSNTISSSSKTVSGFDIKEVAYIYLNLKKMKLPITFATPHGGMAPDPSSKE------ETEKDSYVRDTSLLDRFHDTKPLSSINPEEYSIVLIPGKYATMVDLASNDTLCKIIDAYFKNRGIIGTIGHGVCALFSCQSEEKDKNFLKGRRCTGPTNEEEKILNI----DHCLPYLIEDRLRECGAHFE-SAHPFSPFVVVDERLVTGQ------------------------ +--MKEIVVVLSNATSVG---KRKTGFDLKEVAYLYDF-VRYNTKLIPASVLGGPCGDPFTIQ------EADDDEVCSSSNLLDELRKTIPLYEISISGYDAVVLVGGLGASVDFPGNAQLGKFVSTSVANNKIIGAIGHGVFGLLAAVDKNKI-SLVHEKQVTCATNQENDLRDV----RKYITLDLENDLKVRGAKLR-IGPAFESHVVKDGNLITAQNSQSSAEFCQ-------------- +--KNQIVMIMTNTTQLK---QNTTGFNAIEAEYM----QEENMKLVFASPRGGECRSPRSKE------EAERDPNLENNHVCECLKNTKRISELNSEEIFAVVLIGGHGCLIDFPQSNELPQLLQNWYQNRGIIGAIGQGSIALLNMKS-DKGQPFLKSRRITCMSNEEEKSLK------EEVPYYVEEKLESVGARVE-TQSPFKPNVIVEERLISGQNPQSSHEFSQ-------------- +--LNKIVIVLTTVTDMKSGSQPTTGFNAVEAGYSWKSLKQYNMEIVFASPRGGECMSPKSSE------EAKRDFELES----------------------------------------------RQWYENNGVIGAIAQGSIGLVNMKNPRSGEPFLKNRKITCMTSDEEKKLN------EDIPFYVEEKLEELGAKLE-TQSPYQPNVVIEERLVSGQNPPSARQFGE-------------- +MAPK-VLVVLTSQAQIPD-RDHATGWYLPEFAHPWEVLHEK-VELTIASPKGGEAPLDPSSVEAFKSDPVSSKFLKQESLWHKLADFLPRVSEFDA----I-FYVGGHGPMFDLHYDETSLSLIQAFAAAGKPVSAVCHGPTVFIKAT-TKSGQPLLANSTVTAFTNVEEDQA----QLTALMPYLVEDELNKPGCKFVKADQPWGEKVVVDGTLITGQNPASATG----------------- +--LKRVLLVSTSAHDL---NGHPTGLWLEELAAPYHLFKKAKFDVDIVSIKGGRVIDRVSIP----NGIPR-EFKHVAS----LLQNTRAISTVHSSEYDAVLFCGGHGAIVDFPGNPYVANLIENMYNNNRIVAAVCHGVSSLVGVKNK-DGSFFVAGKRITGYTNDEEKAVHLE------------------------------------------------------------------- +-----------------------------------------------------------------------------------KLKTTMKPSDVDISKYKVIFYAGGHGPMFDLPKNEEIAKLCAKAYEGGAVVCAVCHGTVGLVP-VKLSNGESIVKGQTITSFTNAEEEFVKLTEAMP-F---LLETKLKDLGGNFVGAE-NFQVNVQTSGRIVTGQNPPSAGPMAEK------------- +---MKTILMVTSSHDRFEPDPRPTGVWLEEFAVPYMELRKIGI--TVASPRGGAMPVDRSNP----TPEQQQQWQAAIEASRATLPLA----GMASENFDAIFLPGGHGPMFDLPDNPDLARLLTEFYKAGKIIAAICHGPAGLVGA-RRPDGAPLVAGVTLTSYTASEEVAAELDKEV----PFILEDRLRALGAHFIARENKA-DHIERDGQFITGQNPNSSTSIARAIV----------- +MSQPKILFVLTSHNK-MGDTGKPTGWYLPEFAHPYEVLAPHT-QITIASPSGGASPDPASIEASFLKEKEK-LWTEKLSSF------VGKAAEFDA----IFFV-GGHGPMWDLSQDATSHQIINEFASAGKIVSAVCHGPAALAHVRT-PAGDYLLKDHAVTGFSTSEEDAVGLTQAMP-FILED--QLKVASGGKYRKADGDWAPNVVVSGKIITGQNPASASGV---------------- +---------------------------LVEFTHSYTVFKNAGCSVTVASPKGGLGPADSQGFAFYANDPDSKPLVAKRSSYVPLTENTTAAGSTNLANFDILFFVGGTGSMWDFANDANLHRIIRVMWESGKVVSAVCHGPMALVHA-KLSDNSSLVAGRAMTGFSNAEEEWLGSSNEYAKQGSFLLEDGLKASGAIYMSTQQDWARFYVRHGRLVTGQNPGAGRETAEAAY----------- +---------------------EPTGLWLSELTHAYDIFEAKGYEQRIVSPQGGPSPLEPRLAKAWLNDPARM----------ALLSQTARPDEIDPAQFDAIYFTGGHAVMWDFPDDTGLQELARAIWERGGIVSSVCHGYCGLLNI-KLRNGTALVAGKRVTGFAWSEEVVA---------------------------------------------------------------------- +-------------------------FRDEEYDIPKKILEDAGVKVITASNKTGTGKFGLKAKSD------------------------ILLEDVKPEDFNAIVYIGGSGASV-FFEDGSALKLANRFYTDKKITAAICIAPTILANA-------GILKGKKATVFPDGI-------EAL------------KKGGAIYS------KKNVETDGNIITAANYETAEE----------------- +-------------------------FRDEELFEPKKILETAGIKTVITSTESGKGSRGRTAQID------------------------LPIRNVHIEDYDILILIGGPGAVA-LADYKEVIDLVKRAKELGKKLAAICIAPYILAKS-------GVLTGKKATSFPSEPA-----ITEF------------VNQEVIRI------QEPVVEDIDLVTADGPTSAKD----------------- +-------------------------FRDEELKIPFSILDKAGIECYKASPIKDFGK--LQISPD------------------------FSIKEIDYKDFDGICIVGGPGATEL-KKYPETLELIKNFFNAGKLTTAICIGPSILGAA-------GILKDKKITLFPDRIA-----IDEL------------KKVGAQLI------EKDLVEDDNIITANGPKAAEK----------------- +-------------------------FQDTEYEKTTEVLKKGGVQVTVASQTTDTGKVKAKVTPD------------------------IAVSKASVKDYDAVVIIGGPGTDS-LAADASVISLVKDARKMGKTVAAICIAPIILAKA-------GILQGRKATVFSTGR-------KEI------------EAGGAIYQ------LSDVVIDKGVITGSGPEASTK----------------- +-------------------------FRDEELFEPMAVFESNGLKVDVVSTTKGVGMLGNKITTE------------------------KTIYDVNANEYDAIVIVGGIGSKEYLWNNTRLIELVKEFNSQNKVVSAICLSPVVLAKA-------GILKNKKATVYPAQEA-----IEEL------------KKEGAIYE------DKGVVVDGNVITAKSPDYARL----------------- +-------------------------YQDIEYNDPKTVLEVSGHQVVSAST-TKYGSLGGKISVN------------------------LLLKNAKVEDYDGIAFIGGPGSYI-YFNDPVAQKLAQSFYAANKLTCAICAAPSILANA-------GLLDGKIATCYPGQA-------ENL------------KAHGAHYT------GNPVEQDGILVTASGPPAAKA----------------- +-------------------------FEDVEAIGTIDILRRCGLQVQTLSVKR-TSA--VVIKAD------------------------SIFRKNHLLNCEAMVFPGGLKGAESMAKNTILRQTVMQQVMQGTLIAAICAAPMILGAA-------GVIRNKHVTIYPGEA------------------------HEGIYHN-----NAYVVEHDNFITASGPAATRY----------------- +-------------------------FRDCEYITPRAFFEQAGIEIVTASTT-GTGR--YKVHAD------------------------LLLEEIDARTFDGIYFVGGAGSAQYLQDEI-AKSVFNSFLHLNKPIAAICAAPRNLLKW-------DMLKNKRATGFDADGI-----FSKM------------AAEAIALP------QEKVVTDGLILTANGPEAAEE----------------- +-------------------------FRDEEYLEPRDVLEDAGVSITVASNSTKYGALGAKIKPD------------------------ISIKDAIMAEFDGIVVVGGGGSREHLWPNKDLQRLVKDAFDQDKLVAAICISPVILARA-------KVLEDRDCTVFKDKEC-----IAEL------------EKYGGHYQ------DTDVVADGNIVTARDPKAAEK----------------- +-------------------------FRDEELFVPKEIFEKEGFEVVVASNSPGIGKLGGTIPVD------------------------LVISHVHPDDYAALVVVGGPGVAV-LFNNLELFGIARDFSQKRKVTSAICSAPVVFANA-------GILNSKKATCFSEQR-------DKL------------ENGGAFYT------GRLVERDGDIITGSGPAASED----------------- +-------------------------FQDEEYFESKKIFEAAGYKTEVSSTFIGQGK--GMTNID------------------------LLFSEVDAVEFDAVVFVGGIGCITL-WDDWRTQGLAKLFLDNQKIVAGIGSGIVIMANA-------KILEGINVTCLPADESH----VRH----------------NANVL------KDNVVVSGNIITSNGPASSKE----------------- +-------------------------FQSKEYFDTKDVLQNEGIHVVTTAPLHEYSH--DEVMPD------------------------LALSDV-VTDYDGVFAIGGPGALEYLD-TTETARIFMEAHQENYPYGAICIAPRILAKA-------GVLKNVHATGWDGDGEL----QRVF------------DTYGVIRV------EESVVMDGVVVTAHGPAAARD----------------- +-------------------------FRDEEYFIPKEVFERAGASVITFSTAIGVGVHGGEVPAQ------------------------LTVEELKVADYDAVIFVGGAGAKK-LMENEDALRVARETAASEKILAAICIAPTILARA-------GVLFGKKATVWSSSMDRS--AIKIL------------QEEGVLYR------EGPIVVDGKIITANGPEVARE----------------- +-------------------------FKGIEFLNPSNILKAAGHKIFVASNTGERGA--MEVKID------------------------YSLEETNPENFDMIVFVGGLGALENLD-NEESYRIIRETLAIGKPLGAICIAPVILAKA-------GILKNKKATVWSSPMDKN--PIEIL------------RKNGVDYQ------NQAVVADGNIITANGPQASEE----------------- +-------------------------FRDEEYIEPKTLFEQHGARTVTISTTLETGM--ATVQAT------------------------LLLKDAQADNFDAVVFVGGMGARRLYHEPE-ALRLARQAVAHNKVVGAICLAPNILAQA-------GVLKNRRATAWAFEVP-----A------------------AVNQV------GESVVRDGRIITANGPQAATP----------------- +-------------------------FRDEEYFIPKRTLEEADAKIETFSDSLGMGM--GEAEVD------------------------GLIENLNSKNYDAVLFIGGSGADDYID-NPACHKIVRETIEAGKTVGAICIAPAILAKA-------RVLSGKKATVWSSALDKS--MVKLL------------KDCGAVYR------SDPVIADRNIVTASGPDFAEE----------------- +-------------------------FEQTEYKKTRAALDDAGVVCSIASTKVGKGN--KRIESS------------------------MLLKDVNVADYDAVVFIGGNGIKKVWK-NENAHKIAQEAVKQDKILAAICAAPGILGYA-------GVLEGKQATAHPKSGA-----RKVM------------TKNGCNFQ------SEKVVVDGKIITANGPKAAGK----------------- +-------------------------FRDEELFKPRELFIKEGMEVILASSSLERGMLGGTAKPD------------------------ILISKVKVEEFDVIIFVGGMGSSE-YWDDPVAREIVKKAVSLDKLICAICIAPVTLANA-------GILDGKKATVFRSEV-------KAI------------KKKGAIYT------GKAVEVDGNIITAEGPQTASE----------------- +-------------------------FNSQEYDAVKKISNNVTI--VAADKDIGYD---------------------------------VYIGDIKISKYKAIVLVGGPGVYQRVTGMEMVIKFVKIANSKGKIIGAICASPAILAKA-------GILKNKKATVYPSDDL-----IRIL------------KENGVNYT------KSAVVVEGNIITASDPTAAQD----------------- +-------------------------YQDIEFNTPYKMLVDNGCTVDVAGLDDGQGA--GSFTPN------------------------KLLSVMTIAAYDALVIPGGPGSIDYLWNNAKLNQTIKTFYNAKKIVASICHATAAVAKT-------GILNGKKATGFPSTEL-----KKVF------------NQEGVDFV------DQGCFVSENIITAQSPKFAKE----------------- +-------------------------FQDLEFLEPYKILKEGGIEIDVAGLKPGKGM--RTFEPN------------------------LLLDDLNFDVYDALVIPGGSGSTEFLWEDLKVLETIKYFHSKNKIVAAICHACAAVANS-------RILTGKEATVFPSDEA-----LDVF------------KKNEVKFV------DKGVVIKDKIITSQGPKFARE----------------- +-------------------------FNEDELFLPKAELEQAGIVVTVASTKTGTGD--GKAVAE------------------------AVFSDLPTGDYDVVAVIGGSGTIDYLWGDDKLQQYVKEAYDRNILVAGICAGSVAVVKT-------GLLKGRQATCYPVDVM-----IDQL------------KANDVDYV------VEHVVAHDDIITSDGPEGARA----------------- +-------------------------FQTLEYDNPKHTLTEAGHIVITASRDGGIST--EKIETD------------------------LKLSDV-TSDYDGVFVIGGPGSIEYLN-NNETARIIGEAKSPHV---------------------------------------------FC------------DKYGCVRE------LHPVVRDGRVITADGPSSASA----------------- +-------------------------FIDMGYTVPKRILEEQGVECLTASTIHGYGMHGEIVESD------------------------FSFSEVNPADFDGIVIDGGIGCQDELWRNEKLIDITNKIGVSGKLAAAICLAPVILAEA-------GLLAGKKATCLQTPAT-----LRVL------------TLDKAEIV------QDKVVADGSIVTAQTPFDAEE----------------- +-------------------------FRDEELFVPEDVFSGVGAFVLTASTTKKYGS--GSTLPD------------------------LHIEDIKVDSLNALVIAGGKGAREHLWHNEALLRKVREANEKGKVIGAICISGAIPAIA-------GIMRGRRGTVYPDTGA-----LEVL------------KENGETYV------NEGVVVDGNVVTGAGPTYAKE----------------- +-------------------------FRDEELFEPLGILEENRIEYEIISTDKGRGM--GYATAT------------------------ETISGILMKHYGGLMIVGGSGSKDYLWGNEELYTIVRYFDKAKMPIGAICLSPVVLARA-------GVIAGRHATVWPDKEA-----VREM------------EKHKAIYE------NKPFVSDGRFITANGPTAATE----------------- +-------------------------YRDEELAEPVAALTKAGIAFDIASTRAGTGMLGGKATAS------------------------LSFDEIDPNNYKGLIIVGGAGSQTYLWEDDILVQLASYFHGKDKVVAAICLAPVVLAKA-------GILKGKKATVYDSPVA-----VLEM------------KKGRALVT------KDLVVTDGRIITANGPAAAKA----------------- +-------------------------SYKGEYSMAVQALRQLGMEVSTGLVSVN-------VNFD------------------------IDLTGGLLSNYDAVIYIGGYWAYYASTGKEVFEEILTQSVNGGKTTILPLATPAYAAKL-------GLLKGKKATVYPTTDL-----ITIL------------RNNGVEYI------NDNFVIDGSIITLKKVTSLTK----------------- +-------------------------AKRDEYPTLKNFIAKAGYDVRTAVGDVN-------VNYQ------------------------VDLETAGAAEYDLLALAGGYKMYYHVLKIERLNALVTRFSKNDRLVVAPLAVPGYLAQL-------GLLRGKNATVYPITEL-----IRIL------------RENGANFV------NQHVVKDRGVVTVDDITGEKE----------------- +-------------------------AKREEYSMLKNYLLKAGYEVKAAVGDVN-------INYD------------------------IDLMTTPAEDFELLALAGGYKIYYYVLKVEKLNTLVESFNKKGRVIVAPLAVPGYLAQL-------GLLKGKEATVYPITEL-----INIL------------KENGASFV------NRQVVRSSNIITIKDITEEKD----------------- +-------------------------YHDKELAQVMAVFDQNKIPYEFVSREKGKGT--GRVYVP------------------------LSFEEVIEDEFDALAILGGHGAQAHFWNNPDLLELVKIFRIHRKVIGAISTAPVVMARA-------GILKKRPATVISG-AP-----IREM------------MKMDVKFE------DKPFVFLDRLVTARDPGDAKR----------------- +-------------------------YQPIEYCNTRKELEKADIAVMTASDKAGIDCEE--EKVT------------------------LTVKDLLLDTLAGIFLIGGGGALDCLD-NEDTQELMRRAEKNGLWYGAICISPRILCHA-------GLIDGKKITGWDNDGKL----KSEC------------AKSDVV--------GGPVVVDGKLITAQGPKAATE----------------- +-------------------------YQPVEYAEPKKILHDAGFHVVTASDKPGKDK--NITKVD------------------------LTLKDV-VNAYDGIFFIGGPGALECLD-NEESYRIIKRAAEKHLPLGAICISTRILAKA-------GALTRHRATGWNGDNEL----EKIY------------AEYDVKYL------PEPVVVEENIITAIGPTAAKT----------------- +-------------------------YQELEYQMPKQILEKAGILTTTASRKSGLGH--GSTTAN------------------------LSLDQVHVDEYDIILFVGGPGAVLYQH-DAEAHRIAQEAIQKKKLLTAICIAPTILAYA-------GVLQGKKATVWNADGEQ----QAVL------------EKNGATYT------GEDLTLDGSILTANGLAMAGK----------------- +-------------------------FRPEEYFYSKEEINNGGFKVITAGKDKIRS--ITSAKTD------------------------KTFDEIEDKNFIAVVVPGGSPGWLNLLKNDKVLHLIKHAGEKGMFVASICSSVAVLSKT-------GILKGKKATIWPGDNDV----ITGI------------PINDESFIQ-----KTVVVRDGKIITANGPWASRE----------------- +-------------------------FEQVEYTQTNDLLKAKGHQTTLITT--------D-F-AD------------------------LLIGEANAADYDAIVLPGGGANADVLRANTDAQAMVKAFMNVGKPVAAICHAPWIFADT-------EIARGKKLTAYKTATD--------L------------KNAGAQFE------DKSVVID-NLITSRQPEDIPD----------------- +-------------------------FEQAELVEPQRALTQAGAHVDIVSR------------VD------------------------VTLDAADATDYDALVLPGGVVNGNAIRLDAKAQSFVKEADEAKKPIAVICHGGWLPISA-------GIVAGRTMTSWPSQDD--------V------------RNAGGTWV------DRKCRST-ISSRAASPTICRS----------------- +-------------------------FEDAEVSQVKYTVEKAGGRVLIVAP--------T-Y-PD------------------------MVTADVDAASFHGLILPGGVGNADQLRVDAAAVALVKGMADAAKPIAAICHGVWILTDA-------DVLHGRTVTSSPTRTD--------L------------VNAGATWV------DEEVHVDGVLITSRTKADVDA----------------- +-------------------------FEDTEVSQAKHAVEQAGGRVLIVAP--------T-F-PD------------------------MITADADAASFCGLILPGGVSNADQLRLDEHAVELVRGMATAGKPIAAICHGAWILTDA-------DAVTGRTLTSSPTRTD--------L------------VNAGATWV------DEEVCIDGLLITSRTKADVDA----------------- +-------------------------FNQHDLIEAQKALLAAGAKVKIISPDQGSGWDGHNFPVD------------------------QALATALGADYDMLVIPGGSRALDKLQTTAHTRRFINNFMTMAKPVALFGDAASILVFA-------EQANGRVVAVADSAK-------DVL------------VAAGATVV------DDVMAMDGNLMSSPVGEQRQS----------------- +-------------------------FDETAFIAIQRVMMTAGGKLRVVSREAGNA-NGMSYPAD------------------------ATLSTTLAIDYDALIVPSGSRHIENLKTDAHAKRVLRAFLREDMPVLLQGEAISLID----------LIEDDADRP--------------T------------ISNGD---------G-VPVVDRNLVTVAAASEALD----------------- +-------------------------FDEDQFIAIQRAMLAKTAKLKIISRDAGNS-NGMSYPVD------------------------STLSTTLAIDYDALIIPTGARHVDTLMNEVHAKRVLRAFLREGMPVMMQGEAIRLLD----------LVEDHAARS--------------I------------DAKDE---------NAEVAVDKNLVQIPLAVKLES----------------- +-------------------------FEEIELEKPRNALEKEGAKTFLISP---------TF-VD------------------------VPLK---ADDYDALLLPGGVINPDRLRTIPEAINFVREMNNQKKPIAAICHGPWLLINA-------DAVKNHKVTSWSSKID--------L------------INAGAKWI------DEPVVSDDNLITSRKPDDIPL----------------- +-------------------------FKEIELKSPKIYLQNKGFQVDIVSP-GP--------PID------------------------VHLAEA-PAVYEALILPGGTLSPDALRVLPKALDFIKHFIEQKKLIAAICHGAWPLVEL-------DYVKGKRMTSVSNRSD--------L------------KNAGAIWE------DEAVIQDGNLISSRTPDDLEF----------------- +-------------------------FDEWAVKGSKPFFKAHNFKTHLISP--------S-Y-ID------------------------RHIKKADPKLYDALLMPGGALSVDNLRTNAEVLAFVDHFIKEQKPIGTLCHGIWPLVEL-------GFVADRKLTSVKTKTD--------I------------DNAGG-WI------NESSVRD-LLVTSRTSEDLEE----------------- +-------------------------FEQSELEVPRDKLKAVAQLVHVAAPR--------PV-VD------------------------VELS---TSLYDALVLPGGQMNPDTLRKNPDALKLIRAFLNEGKVVAAICHAPWLLIET-------NAIRGRRATSYDSKTD--------V------------INAGAHWV------DEPVVADQGIVTSRNPGDLEA----------------- +-------------------------VEQVELTEPWKAVTDAGHEAVMLAP---------TQ-VD------------------------QTVG---VDDYDALVLPGGVANPDALRQDQQAVRFIKEFVASGKPVAAICHAPWTLVEA-------DVVSGRRLTSWPSQTD--------I------------RNAGGDWV------DEALVQDGNITTSRKPDDLPK----------------- +-------------------------TEEPEFLKPKQAIEEAGGKVTVVSF---------SY-ID------------------------KTFA---VDVFDGLVVPGGTVGADMLRGSGEAIDFIRAFFDQKKPVAVICHAPWTLIEA-------DVLKGRTLTSYPTKTD--------I------------ENAGGTWI------NEEVVVDKGLVTSRNPNDLPA----------------- +-------------------------FEQVEDDGTAESARRGGRRYEDRLA---------RV-DR------------------------RFPR---PADFDALLLPGGVLNPDRLRIEPRAVAFAKSFFDAAKPVAAICHGPWTVIET-------GAARGRRIASWPSKTD--------L------------RNAGAEWV------DREVVVDGNLVLSRKPDDIPA----------------- +-------------------------FEQEEMTGPQAALEESGVMIRLLSD---------SF-VD------------------------TTFD---ADEFDAVLLPGGAVNASRIRNNADAQELVRQMDQQGKPLAMICHAPWLLVSA-------GLVKGRKMTSAPEQKD--------L------------EQAGAQWV------DEKVVVDRNWVSSRKPADIPA----------------- +-------------------------VEQSELAQPRAALQEMGVITRLLSA--------D-F-VD------------------------MTFDKADAFAFDGVLLPGGEKNAAALRHHPQAQAFVRAMDEQGKPLAVICHGPWLLASA-------GLVQGRRMTSYPAADE--------L------------RQAGARWE------DAPAVRD-HWISSRTPQDLDA----------------- +-------------------------VEDIEYTSPKKALTDAGNEVTLVGT---VGK--T---TD------------------------KGIDDI-ADNYDALLIPGG-FSPDNLRAD--FVELAKKFMLNDKAIFSICHGPQLLMQT-------GLVKDRTLTSYKTQTD--------L------------YYAGGIVK------DEPVVID-HLITSRNPDDLDA----------------- +-------------------------FEDVEYIKPSEAFVNEGHSIVHIGI---KGK--T---IE------------------------ESVSKY-IDDLDALMIPGG-CSPDHLRGYESAVNFVKNFFKTGKPIFAICHAPQILITA-------DLLHEKKVTGWRSVQD--------L------------KNAGAIYI------DNEIVVDDNLISSRGPKDIPV----------------- +-------------------------FEEMDLTEPRRALEEAGAIVTIVGI---RGK--L---AE------------------------ELVADC-AEDFDALLVPGG-LSPDRIRADAEVQRFVREFDAAKKPIFSIGHGAQVLISA-------QLLRGRQLTGAHSADD--------I------------RNAGGLYR------DQPTAQDSNIISTRGGEDLPQ----------------- +-------------------------FEDSELLYPLYRFREACADVTVAGI---KGK------SE------------------------AAIRDL-PDEFDALVIPGG-QSPDHIRIYPEVIKFVQDFDRTGKTIAAVCHGPQILITA-------RLLKGKDATAWKSRVD--------M------------EDAGANYI------DKPVVISQQYIFSRQPSDLGF----------------- +-------------------------FDEQELIYPYHRLREDFEVVLVGSK---KSK--F---SD------------------------LASEEI-PEEYEALFIPGG-FSPDYMRRTEATVNLVKMFIKTGKPVAAICHGPWMLASA-------DAIKDKEVTSFFSKND--------M------------IHAGGIWI------DKEVVVSDNILTSRNPGDLPA----------------- +-------------------------FRDEEVIYPYYRFKEAGYDVKVVGT---KGK--V---SD------------------------LSASQI-LDDVVALIIPGG-NAPDKMRIQKNMVDLVKRASRQQKIIAAICHGGLMLVEA-------DIV-GRKVTGYRAATD--------L------------KNAGGQYL------DKEVVVDGNLVTSRIPDDLPA----------------- +----------------------------MEVMWPKMRLEEEGAEVVVIGC-AGNGK--YPVRSA------------------------KSIDDD-ADQWDALVLPGGF-APDYYRRSSKMLTLTTAMAAAAKPIAAICHGPWMLCSARRA-DGTPLCTGHQVTAFSAKDD--------V------------INAGATWM------DQPVVVTEIIVTSRTPNDLVP----------------- +------------------------------VWYPLLRFQEEGFRTIAIGP---------------------------------------------------------EKLKSYTSK-KSDTSIDAVTVAVGKPVAAICHGAWMFCSA-------RIIKDRKLTCFHAKDDV----INAR------------PEF----Q-------E-ICHSRRSSNSCRPS--KQ----------------- +-------------------------YQEMEFWYPLLRLREDDVPVEVVGEDVDHSR--YPVLPE------------------------RALSDAAVDGCSAILLTGGKLAAHNHG---PVLAWVKAAMGAGKTIGITSGASWILEAV-------DIASS------G------------G------------PESGVR-----------VLAGGKVVAAGSAEDLPQ----------------- +-------------------------YQEMEAWYPYMRLIEEGAKVTVVGP---QSK--Y---AD------------------------VSIDQV-AADFDAVVVPGG-FAPDHMRLCRPMIDLVRDVHARGKLAAAICHGGWILSSA-------GIVKGRKVTGYLPKDD--------V------------EAAGGTWV------DEEVVQDGNVITSRTPPDLPA----------------- +-------------------------VEDVEFIYPYLRFKEEGFEVISAAP--KRGK--MTFTPD------------------------ATLSEV-GRLFDCLFIPGGY-APDRLRRYPQVLSMVKKHLEEDRLVAAVCHGPWVLISA-------KVVKDRKVTGFYAKDD--------L------------ENAGAIYT------GKSVEEDGNLITATDPSSMLQ----------------- +-------------------------YEDLELHYPRLRLEEAGFDVVVAAR--------Y-A-SN------------------------AAFADVDPSDVAVLVVPGGLLCPDRLRRYPEALGLVAGVAAAGGVVGMICHGPWVGISA-------KILDGVRATCFSAKDD--------V------------INAGA-YV------ADERVVV-RIVTAQTPNDLPG----------------- +-------------------------FEDIELLYPLYRLREAGYDVTLVGT-SKTGT--YIVDVD------------------------ASAEEI-ENNYDGVIIPGGS-ASYKLRTNDDVKRIIRHMKEKDKLLAVICDGNYVLISA-------KVLSGHKVTCTEASDD--------V------------INAGGEYV------RIGNCVDKNIITAKMQVNLPQ----------------- +-------------------------FEDIELLYPLLRLREEGIRVIVVGT-LKVGK--YTIDID------------------------ENANTI-PLDYDGIIVPGGW-APDRLRTNIYVKNLIKDMAENNRAIGCICHGASVLVSA-------NVIQGYKLTCTDSIDD--------V------------INAGGDYT------SEGNCVDRNIISAKIPGNLPE----------------- +-------------------------YQELEVWYPYYRLREEKAEVTFIAP---HGK--Y---AD------------------------ITIMNA-PEHFDAVIIPGG-FAPDFMRRTPEMIGFVRKMGEQKKILAAICHGPWILASA-------GLLQGKKATCFFATDD--------I------------KNAGATYL------DEPIVVDGNIVTSRKPDDLPA----------------- +-------------------------YREEEFEVTARMLSDAEIEYDVASTKTGIGMMGGEQEAG------------------------LEISKAVEKDYDALILIGGLGARDFLWADDDLCRLTKEFGDAGKVIAAICHAPVIVARA-------GVLKGRQATVFESRAS-----LKLL------------EDGGANYV------NIPVVSDMNIITANHPVAAKQ----------------- +-------------------------FEDSEMKAPYDAIRADGHETVIIGL---EGK--A---TD------------------------LGIQDA-ASDYQAVVIPGG-SSPEALRNDHDIQKFVQKFDEEGKTIAAICHGPQILISA-------GLAKGRTLTCYPPRDD--------L------------ANAGAHYV------DQEVVVDRNFISSRTPKDEPA----------------- +-------------------------FEDSELRVPYDQLRGAGHEVVLIGK---EGK--E---LE------------------------RGIDEV-VKDFDMLLIPGG-HSPDNLRADERFIRFVKEFDDRGKLIAAVCHGPQLFISA-------GIVDGRTLTAWTTQQD--------L------------KMIPNVVR------DASVVRDANWITSRKPDDLED----------------- +-------------------------FEDAEFRVPYDEVKKAGHEAVIIGV---KGK--E---AE------------------------KSVKDV-EEDFAALVIPGG-YSPDHLRMEIPMVGFVRDFFKADKPIASICHGPWMLVEA-------DIADGRTVTSFPSKTD--------L------------INAGARWV------DREVVEDGGLITSRKPDDLKA----------------- +-------------------------FEDSEFTSPAEAFKLAGHQVITIEK-AGKGK--AEVAID------------------------RAIDDVTPGEFDALLLPGG-YSPDQLRGD-RFVTFTRDFVNGGKPVFAICHGPQLLISA-------DVIRGRKLTAVKPVVD--------V------------KNAGGEFY------DQEVVVDEQLVTSRTPDDLPA----------------- +-------------------------FEDIEALYPYYRLIEAGFDVTVAAP---EGK--Y---NS------------------------KAIKDI-PDDFDILVLPGG-RGPERIRVSDDAVRIVKSFYDSGKPIAAICHGPQLLLSA-------GIVKDIKLTSYPGADD--------L------------KAGGAEWL------NEKVVVHGNIITSRLPEDLPY----------------- +-------------------------FDEREFLYPYYRVQEAGYTPVVIGP---RAK--F---AE------------------------VSA--R-APELAGLLIPGG-FAPDYLRRSPEVLALVRRVAEGGGPLGAICHAGWVLISA-------GLVRGRRVTGFSSRDD--------L------------ENAGGLYQ------ETGVVVDGNLVTAQGPKDLPG----------------- +-------------------------FEDSELTYPYYRLQEAGIDVALATP---TGK--E---AD------------------------LAIADA-EDEYDLLVVPGG-NAPEDLRIEEEAITLVREFDASDKPIASVCHGAQLLISA-------DILTGRKATGFWPEVD--------I------------ENAGATFV------DEECVVDENLITARYPDDLPA----------------- +-------------------------FEDLELFYPYHRLKEEGIDVKVASS---RGK--YSLKAD------------------------MHYEDV-PREFDILIIPGGK-SPERVRLQHRAVEITRHFFAENKPIAIICHGVQVLISA-------GVVKGRRIACWYGKDD--------L------------IAAGGEFV------D-GVSVDENLVSARHPGDLAE----------------- +-------------------------FEDTELLVPLYRLREAGYTVDVASE---HGK--Y---VN------------------------KLFNEV-PADYAVLVLPGG-KAPAAIRNSPAVHEIARAFMSSSKPVAAICHGPQILISA-------GLLKGRKATCYETAPE--------L------------RDAQAQYQ------DVEVLVDGNLITSRKPDDLPA----------------- +-------------------------VEALEVFYPYYRCLEENINCTIASPKEMTEK--YKLESH------------------------ASVDEI-PADFDGLIIPGGR-APEYIRLNTKVQEIAAHFLKESKPLGVICHGQLVLTTVR------QYIKGRELTAYNARPE--------V------------EASGATYI------EKMLHVDGNIVSGHAWPDLPG----------------- +-------------------------VEALEVFYPYYRCLEEDISCTIASPKEMTEM--YKIDSH------------------------ASVDDI-PADFDGLIIPGGR-APEYIRMNPKVQEITAHFLKEDKPLGVICHGQQVLTPVR------EYIKGREMTAYIARPE--------I------------EAAGAIYI------EEHLHVDGNLVTGHAWPDLPG----------------- +-------------------------FDDLEFFYAYHRLLEEGFEIDIASHYRPKGK--FEVEAT------------------------LSYREA-LDSYDVLVIPGGR-SPERARQHREAVEIARRMAEKGKPIIAICHGPLLLASA-------SVIRGRRVTGYPGKDD--------L------------VNAGAEYV------DAGAVLDGNIVTVRHTSSMGE----------------- +-------------------------FEDIELWYPLLRLSEEGAEAIIVAV-KGTGR--TEEGKR------------------------FTLAKL-SGKIDAMVIPGG-FSPDALRIHQGCLDLVRSLYEKNKIIATICHGPQVLISA-------GIVRGKSMTSYEARDD--------L------------INAGANYE------DSPVVVDGNIITSRVPDDLPD----------------- +-------------------------VEALELFYPYYRLKEEGWDVDV-AP-GWS----Y-FKVT------------------------KTLSEVRPEEYDGLVIPGGRMPEVRVVALEDIKRIVRHFFETGKPVAAICHAPQILAAA-------GVIKGRRMTSYIARPE--------V------------ENNGG-WV------DQEVVVD-NLVTSRAWPDNPA----------------- +-------------------------AEELDTMYPYYRVQEGGWDVDVSSRLNSVEK--RKLPVD------------------------VPWADV-VERYDALIIPGGR-APEWIRVDADVRRITEHFFARNLPIALVCHGAQVPAVY-------GLLKGRKTACFPPTGD--------M------------ENAGATVI------DAPDVVDGNLVSCRGWPDMPQ----------------- +-------------------------VEHDELIQPLHFLQSKGIECIHAAI--------A-Y-PD------------------------VDLDHVHYNDYDLLIIPGGAVNADLLHHHPKALEIIQSFNNQAKPIAVICHAPWVLINA-------ELIQAKQLTSHQNRLD--------L------------ENAGA-WV------DEAVHKCWTLISSRSLEDLPA----------------- +-------------------------VDHHELVILWEAVKDAGGKPML-ST--------E-F-VD------------------------GLVGTLKATNFSALVLPGGADHVQTLRGSSETNRIITEFVSAGKPVAAISQGPAILINS-------GVLAGKSLTGWPGADD--------V------------LHAGA-WA------DKDVHFCWMLITGRSTQTLPK----------------- +-------------------------IEHDELAEPLNFLQEKGFVVIHAAE--------A-Y-PD------------------------TTLSEVSVEDYDLLVIPGGTVNADKLRINEDAQRIIQYFTDNKKTIAAICHGPWALINA-------GRVKGKTLTSYKSKLD--------L------------ENAGA-WV------DEEVHRCWVLITSRNPDDLPA----------------- +-------------------------VEQDELVVPTRALRDAGATVVVAAQ--------E-V-PD------------------------TTIEEVDASEFDLLLVPGGTINADTLRQDAGAVSIASAFASSGRPIAAICHGPWLLVEA-------DLVKGKELTSFASTTD--------I------------RNAGGSWT------DRSVVTDFTLVTSRTPDDLDD----------------- +-------------------------VDHAELTSSWRIVEEGGRP-CLLSIRDDRALRRDSFEPS------------------------DGRQGATPVSFDALVLPCVLATPDSLRLQDAAVKFVREFCDTGKPVAAIDYASGVLVSA-------DVLSGRTVTANPTLE-------AEI------------LGVGGSWV------DKSMFVDRSLVTGRSAGDLAL----------------- +-------------------------YEDADYPELIHAFRAARHSVVNVEN---YGY--S---ID------------------------QSIDDV-IHDFDALLIPGG-QSPAQLRDDLRFVDFVRNFANAQKPIMSTCHGPQLLIHA-------SVVKGRRMTSIAPMLE--------L------------MDAGAVYF------DEAVVNDNLYISSRSPADLPI----------------- +-------------------------FEQCELIETRDALVSAGVKVHIISI--------I-I-VD------------------------KIVSNVTAQEYDALILPGGLFNPDALLQDKDAINFVKAFFTDDKPVVAINQGTWMLLEA-------DVLKNRLVASFPTLNR--------L------------RNAGA-IV------DRDLVVD-GLYTSRSSHNLAA----------------- +-------------------------FEEAEMTEPQRALIKTGATLRTISTETGNGWHGHYFPVD------------------------KHLSEALGADFDMLLLPGGERSVAKLQQSAHTRRIVGHFLDAGKPIAAIDQGIQLLAIP-------GKLRGRLLAAPEAYR-------ADL------------TAAGGRIS------EDALVVDDVTVSALGQDQLNE----------------- +-------------------------FEEVQMTDAQKALIASGAQTRIVSRENGNGWHDHFFPID------------------------ADLTQTLAIDYDALLIPGGARSIAKLLDDPHAKRIAKAFLKGNQPVVAFGDAISLLAIT-------EELAGRTVTGEDSTK-------EAA------------EKAGANWS------EEDIVVDGMLVTAKGDAQIGA----------------- +-------------------------YEDLEVWYPKLRLIEAGYQVVCAGL---KGK--Y---SD------------------------AAIRDQ-SSDYVGVICPGG-WMPDKIRREAKVKQLLQEFHADGKLVAAICHGGWMPISA-------GIYRNVRTTGSLGKDD--------I------------ENAGALFL------DQEVVVDRHFVSSRKPDDLPA----------------- +-------------------------FEDLELWYPVYRLR-EGAVVHLAGE---KGK--V---AD------------------------FTYADI-GDQYDAILVPGG-WAPDKIRRFPEVLSLIQNMDASEKVIGQICHAGWVLISA-------KILSGKKVTSTPGRDD--------M------------ENAGAIWY------DEPVVVDGHLVSSRRPPDLPD----------------- +-------------------------FEDLEFWVPVMRLREEGANVVIAGI---IGK--V---SI------------------------HSFLDL-HDDFHGILIPGG-WSPDKLRRYPELLKIIKDMNKEKKVIGQICHAAWVTISA-------KVVNGKNVTSTPGRDD--------L------------ENAGAIWH------DDAVVVDENFVSSRRPPDIPD----------------- +-------------------------FEELEFWAVYMRIKEEGADIKVMGL-KNEGK--GMTASQ------------------------YGPGDF-ADDLDALLVPGGW-APDKLRRVEEYRQLIREMDARGKVLGFICHAGWCAASA-------GIMKGRKAAGSEGKDD--------M------------EHAGAVWQ------DTPALIDGNIVWGRVVEDIPE----------------- +-------------------------FHDLEFWYPYYRLIEDGYEPIVVAP---TGK--T---AA------------------------YTPQSL-ENLPRGVVIPGG-WAPDKLRMSGEIVSLVAQIYRSNGVVASICHGGSLLVSA-------GILKGKQVTSFASKDD--------M------------ELAGAIWV------DEPVVTSEKLITSRKPSDLPF----------------- +-------------------------FEDMELHYPKIRLKEAGAEVLVAGP---TGK--V---SD------------------------LGFNEV-VDQFQALIIPGG-YAPDKLRVDKKVLEITKKFYDQGKLIAFICHAGWVPISA-------KVINGVRCTSVNAKDD--------L------------INAGANWV------DEPVVVDQNFISSRDPNDLPQ----------------- +-------------------------YETVEFHYPRLRLEEAGYTVKAVGP--------Y-G-SD------------------------AVFSDINPAEVKALVAEA----------LPECNKLVHDAAEAGAVVGFICHGAWVPISA-------KVVKGKKVTSHPAQDD--------L------------VNAGA-WV------DEPCVV--KLVSAQLPKDLPA----------------- +-------------------------VHENEVLSIRERASAAGMNLVIASLTGAQSVNGQLLEPD------------------------MAVDQVKPEDYDALVIPDGLYSVDALRGNTLVIEIVTKFLEEGKPLGVIGHAPWILIES-------GLVTNRSLSSWHTLR-------VDI------------LNAGGHWV------KSPVHNDMALVSAASSDYIED----------------- +-------------------------VEEVEILGAHRWLTEHGATVHIVSP-GLP-Q--HWLKID------------------------RYTDEA-AADYDAVLLPGGCWNPDALRMDPHARAFVRAMDEAGKPTTAICHGQWVMVSA-------GILKGRRATAVWNQID--------L------------ENAGAVVL------DEPCVVDGNLITARFPYDLPR----------------- +-------------------------FYDEEYRIIINELEQNDIEFKIASIQKGRSL--ETVNID------------------------LMVSEAKAENFSAVIFLGGKELELI-SDDDTLKLLAFQFNQKNKIVAAINNAPIILAKS-------GIIKGKQVTATALKGKI----ISI----------------SANFL------TQAVAADGKIITADSSAASEA----------------- +--MAKILFIV----GDFVE--------DYELMVPFQALQAMGFVCDAVCP-DKQGDSIATAIHDF-EGDQ-TYTEKRGHN----FTLNQSFADIDPHEYDGLMIPGGRA-PEYLRLNDRVIALVRAFVEQQKPIGAICHGAQLLAAA-------EVIRSKRISAYPACAP-------------------EVKLAGGEYMEL--AMD-QAITDGQFVTAPAW---------------------- +-MSKKVLILG----GDAVE--------ALEIFYPYYRCLEEGFETTIASPSV---KKLYTVTHDFI-GME-TYVEKPAYG----LDSNIAFADVNPADYDALIIPGGRA-PEYIRLDESLPGIVRHFFEENKPVAAVCHAAQVLSVIP------DLMQGREYTAYIACKP-------------------DVTATGATYIE----KD--LHTEGNLVSGHAW---------------------- +-MSKKVLILA----GDAVE--------ALEVYYPYYRLLEAGYEVTISASSI---KKLQTVVHDFT-GWD-TYEEKLGYL----LESNAQFKDVEPSEFDGLVIPGGRA-PEYIRLDEHVKQIVKHFFETNKPIAAICHASLIFEAIP------DVLKGRTLTAYIACKP-------------------GVEIAGGNYVT----DR-TTYVDGNLVSAHAW---------------------- +-MSKKILIVT----GDAVE--------ALEVFYPYYRCLEEGYDVTIASPAV---KKLHTVVHDFI-GME-TFVEKPAYD----LKSHAAFTDISPEEFDGLVIPGGRA-PEYIRMNEALKPIISHFFQENKPVGAICHAAQLLAVIP------ELMQGREYTAYPSCKP-------------------DVLVCGAKYID----EQ--IHTHQNLVSGQAW---------------------- +LMAKKILIVT----GDAVE--------ALEVYYPYYRCLEEGYETTIAAPKK---KKIHTVVHDFL-DWD-TYTEKPGYL----IDAHASFDEIDPSEYDGIIIPGGRA-PEFIRMYDSLLKIVAHFFEENKPVGAICHASLIFTSLR------EHLKGRELTAYIACKP-------------------EVEAAGATYVE----EK--LHVDANLVSGHDW---------------------- +-MGMKVLILA----GDAAE--------ALETFYPLQRLQEEGFTVHVAAPRK---KVIQTVVHDFE-LME-TYTEKLGYR----LQADLSFTEVDPEAYQGLYIPGGRA-PEWIRTEPKALEIVRHFFQANKPVGTLCHGPLVLTAA-------GVVKGRRLAAYGVLKP-------------------DIEMAGGTFVD----DA--PVVDGNLVTGRAW---------------------- +-MSKKILMIV----GDFVE--------DYEVMVPFQALQAMGFEVDAVCP-DKKGEQIATAVHDF-ETHQ-TYLEKPGHN----FTLNADFDNIKTADYAALVVPGGRA-PEYLRLNEKVLDLVRAFS--DRPIAAICHGPQLLAAA-------GALEGKKVSAYPACAP-------------------EVRLSGGEYVEI--ELD-DAICDGNLITAPAW---------------------- +MSAKKVLIVT----GDAVE--------ALEVYYPYFRCLEEGFEVDIAAPHQ---KKLNTVIHDFE-DWE-TYTEKRGYM----IESNKTFSDVNPGDYDALIIPGGRA-PEHIRMNEELPGIVSHFFIADKPIAVMCHGSLVLTTIA------DVVKGRKLTAYHACKP-------------------EVQSIGAEYID----EM--NYVDNNLVSGHAW---------------------- +-MSKKVLILT----GDAVE--------ALEAYYPYYRSLEEGYDVTIASTTD---KVLHTVVHDFE-DWQ-TFTEKRGYQ----IEAHASFDEIDPAQFDALIIPGGRA-PEHIRLHKDFGRIASHFFQNDKPIMILCHASVALTVIA------DDIKGREMTAYFACRP-------------------EVEAAGAKYIE----TR--FHVDRNLISGHAW---------------------- +-MSKKVLMLT----GDAVE--------ALEAYYPYYRCLEEGFDVTIASPTN---EKLHTVVHDFE-DWQ-TFTEKRGYQ----LEAHAAFEDVNPEEYDALIIPGGRA-PEHIRMHPSFPHLAKHFFEANKPIMILCHAAVALTVIK------DVLKNRELTAYTACRP-------------------EVEACGATYIQ----TR--FHVDKNLISGHAW---------------------- +MSVKKVLIVT----GDAVE--------ALEVYYPYFRCLEEGFEVDIAAPHQ---KKLNTVIHDFE-DWE-TYTEKRGYM----IEADKRFEDVDPNDYDALIIPGGRA-PEHIRMHGDLPGLISHFFIAEKPIAVMCHGSLVLTTIA------DIVKGRKLTAYHACRP-------------------EVESIGAEYID----EM--NYVDNNLVSGHAW---------------------- +-MAKKILIIA----GDAVE--------ALEVYYPYFRVLEEGFEAVIASPSK---KVLRTVVHDF--GWE-TYTEKPGYQ----LESHSSFADVDPTQYDGLIIPGGRA-PEYIRLDENIPCIVGHFLEAGKPVGAICHAALVLSALKD----KKYFEGRTMTAYTACSL-------------------DVEGLGANYTK----ET--LHVDNNIVSGHAW---------------------- +--MARVLIIA----GDFVE--------DYEIMVPFQTLQVLGHAVSVVCP-GKSGETIKTAIHDF-EGDQ-TYTEKPGHK----FTLNADFDAVSEASFDGLLLPGGRA-PEYLRLNEDVLNLITAFNNKNKPIAAICHGAQLLTAS-------YVVSNRAISAYPACAP-------------------EVRLAGGEFTDI--AMD-EAITDGNLVTAPAW---------------------- +-MSKRILILT----GDAVE--------VLEVYYSYYRLLEEGYLPVIASPIR---KILHTVVHDF--GWD-TYTEKLGYQ----IGSHLSFSEVIPEEYDALIIPGGRA-PEYIRLDRHIPRIVSHFFETGKPVGVICHGVLVLNALPN----KSYFAGRTMTTYPTLRF-------------------ELENLGAFYTN----QS--TYVDGNIVSVQLW---------------------- +-MMTKVLIIT----GDAGE--------SLEVMYPYQRLLEEGYEVDIAAPSA---KYVQTVVHDFV-GFD-TYTEKPGYL----VKANKAFKDVNPEEYAAIVIPGGRA-PEYIRNDPDVQRIVKYFFNKDAPVAELCHAPLILGSA-------GLLKGRKTAAYPALKS-------------------DVEIAGGTFID----EG--AVVDRNIVSARAW---------------------- +--MKRVLMLA----GDYTE--------DYEVMVPYQALQVAGVGVDVVCP-DKEGDAIRTAIHDF-EGDQ-TYSEKPGHN----FVLNASFQYLKLEQYDGLFLTGGRA-PEYLRLNPRVLDMVHYFMDLKKPVAAICHGVQILTA--------RVLKGKQVTAYPAVRP-------------------EVLAAGGIFMEK--EPY-EAVICDNLVTSPAW---------------------- +--MVKILMIA----GDFTE--------DYELMVPYQALQVVGLEVDVVCP-DKNGDIVKTAIHDF--GYQ-TYTEKVGHN----FILNASFQNI-LHEYDGLFITGGRS-PEYLRMDSRIIDIVHYFMDLEKPIASICHGVQILTAA-------DVIRGLDVTGYYSLEP-------------------EVKSAGGNFIKKE-A-H-EAVICRNLVTSPAW---------------------- +-MRPRVLMLA----GDFSE--------DYEVMVPFQTLETLGIKVDVVCP-GKKGQKIKTAIHDF--GDQ-TFAERQGHG----FTLTADFENI-PGVYSGLYITGGRA-PEYLRLNPKVLNITRYFAAHGRPLASICHGAQILTAA-------DIVQGKRLTAYEALEP-------------------EVKLAGGIFCRVK-P-D-EAVEDGMLVTAPTW---------------------- +TMTVKVLLVT----GDAAE--------SLEVLYPYQRLREEGYEVHIAAPAR---RKLRFVVHDFE-GFD-TYTEKPGYT----WPADLAFAEVDPTGYAALVVPGGRA-PEYLRNDADLQRIVQHFFDAGKPVAQICHGPQITAAA-------GVLTGRRTAAYPALHP-------------------DITAAGATFED----AP--AVTDGPLVSARAW---------------------- +--------MT----GDAGE--------VLEVLHPYWRLREEGHEVHIAAPAR---KRLQLVAHDGV-GFD-TFTEKPAHT----WPADLAFRETDPAGYAGLVLPGGRA-PEYLRLDGDFRRVVRHFFDEGKPVAHISHAAVALAPL-------GVLAGRRTTCWPACAP-------------------DVAAGAGTFVD----EP--VVLDGRMVSAQAW---------------------- +-MAKKILLLV----GDYVE--------DYEAMVPFQAMGAIGIDVDAIAP-ERKGDVVPTAVHDF-TGDQ-TYKELRGHN----FGINKDFDSVNPEEYDGLYIAGGRS-AEYIRLNKRVLEITQHFFNENKPVAAICHGIQVLTA--------KVLAGRTLTAYVAVGP-------------------DIELAGGTWKNI--PAD-QAIVDGNLVTSPAW---------------------- +-MGKKLLMLC----GDYAE--------DYETMVPFQALQIAGHTVHAVCP-NKKGDKIRTAIHDF-EGDQ-TYSEKRGHD----FVLNATFADVNAEDYDGLVIVGGRA-PEYIRMERRVLEMVRHFASANKPIAAVCHGAQVLTAA-------EVIKGRRISAYPAVAH-------------------EVRLAGGEYADI--PID-GAITDGNFVTAPAW---------------------- +-MTKQILMLV----GDYAE--------DYETMVPFQFLTALGYDVHAVCP-DKIGDHIATAIHDF-EGEQ-TYSEKRGHN----FAINYNFENVQPDQYVGLVIPGGRA-PEYLRMNARVIAIVQAFDQAKKPIAAVCHGAQILAAA-------DVLKGKTCSAYPACAA-------------------EVKLAGGTFADI--SVT-DAVTDGHLITAPAW---------------------- +-MAKKLLMLV----GDYVE--------DYEAMVPFQAFQALGYQVDAVCP-DKAGDYVMTAVHDF-EGAQ-TYSEKPGHR----FTLNASFDQIEMEKYDGLVVPGGRA-PEYLRLNSKLLALVRYFFEAKKPVACICHGIQILSTA-------GVLEGYKCACYNTCAP-------------------EVTAAGGTYVDIP--MD-EAITDRNLVTAFAW---------------------- +MSKKRILIIA----GDFVE--------DYEIMVPYQALLMIGHDVDVVCP-GKQGDTIRTAIHDF-DGDQ-TYSEKPGHK----FSLNATFNKIDASQYDALVVPGGRS-PEYLRLDANVVAMVRHFFDENKPVASVCHGPQLLAGA-------DVLKGRQCAAYWACEP-------------------EIRLAGGEYVELP--LD-GAHREGNLVTGSAW---------------------- +-MAKQILVLA----GDYVE--------DYELMVPVQALSALGYVVHVVTP-DKRGEQIRTAIHDF-EGDQ-TYSEKRGHN----FTLNASFSDVDTAAYDALLLPGGRA-PEYLRLNPRVITVIRDFAQAGKPIAAVCHGAQLLSAA-------GVIAGKRISAYPACAP-------------------EVRLAQGEFVEL--DWA-EAVTDGQFVTAPAW---------------------- +MAAKKILMLV----GDYVE--------DYEVMVPFQALQMVGHTVHAVCP-GKAGQTVRTAIHDF-EGDQ-TYSEKPGHN----FALNFDFEQVRAEGYDALVIPGGRA-PEYLRLDERVLALVKAIDKAGKPIAAVCHGAQLLAAA-------GVLEGRECSAYPACAP-------------------EVRLAGGKFVEI--GVD-QAHVQGNLASAPAW---------------------- +MAAKKILFLT----GDFAE--------DYETMVPFQALQAVGHAVDAVCP-GKRGERVKTAIHDF-EGDQ-TYTEKPGHL----FALNATFDEIDPSRYDALAIAGGRA-PEYLRLNPKVIDVVRQFAESNKPIAAICHAAQLLAAA-------DVIRGKRIAAYPACAP-------------------EVKLAGADYADI--AVD-AAITDANFVTAPAW---------------------- +-MTKNILILA----GDFVE--------DYEIMVPFQSLLLLGFQVHVVCP-DKKGDKVKTAIHDF-EGDQ-TYTEKPGHN----FALNYTFDEVKPENYHGLVLPGGRA-PEYLRLNQKVLQITQHFVDTKKPILSICHGIQILTAK-------GSLTGHNVTAYYACQT-------------------EVELAGGKYQNV--AAD-QAVTDHNIVSTPAW---------------------- +MTKKKILMII----GDYVE--------DYEVMVPFQCLEMVGHIVHVVSP-DKKGDFCVTAVHDFLPGEQ-TYTELRGHR----FKLNFDFAAVKECDYDALVIPGGRA-PEFLRLNAKVIELTQQFHHSKKPIASICHGPQILAA--------GVLKGIRCTSYPACKP-------------------ELILAGANFQDT--AAD-KAVSDHNIVSAVAW---------------------- +--MSKILMLC----GDFGE--------DYEVMVPFQALQAVGHTVHAIAP-DKKGDHVMTAIHDF-EGQQ-TYSEKPGHR----FTLNASFGDIDPTKYDALVVLGGRA-PEYLRMNTRVVEIARHFLTNNKPVASICHGAQLLAAT-------GLIKGRKLSAYPACQI-------------------EVELAGAEYVGI--AID-AAVTDGNLVMAPAW---------------------- +MAAKTILMLV----GDFVE--------DYEAMVPFQMLTLVGHTVHAVCP-DKTGQSVRTAVHDF-EGDQ-TYSEKRGHN----FALTATFDEVDPADYDALVIPGGRS-PEYLRLNPRVVEIVRHFIDTDKPIAAICHGQQLLIAA-------DGLAGKTCTAYPALQP-------------------DVERAGANWIAPNETFS-NAVVDGQLVTASAW---------------------- +MGAKRILMLV----GDYVE--------DYEAMVPFQMLQMVGHQVDAVCP-GKKGDVVKTAVHDF-EGDQ-TYLERRGHN----FRITADFDSINPEDYDGLVIPGGRA-PEYLRLNDKIIQIVKHFAEKNKPIAAICHGPQLLTAA-------DVIRGKKLTAYPAVKA-------------------EIVLAGGIWCDVNETFT-NVCVDGNIVTAPAW---------------------- +MSQAKLLMIV----GDYAE--------DYETMVPFQALQMVGHRVDAVCP-GKKGQSIRTAIHDF-EGDQ-TYSEKRGHN----FGLNATFEEIDPAEYDGLVLPGGRA-PEYLRLNERVLAMVRHFAEAKKPIAAICHAAQLLAAA-------KCIAGKRVSAYPACAP-------------------EVELAGGHYVAV--EMT-AAVVDGNLVTAPAW---------------------- +-MSKKILMLV----GDYTE--------DYETMVPFQTLQVLGYDVDSVCP-NKKGDFVRTAVHDF-EGDQ-TYSEKRGHN----FIINANFETIDTSNYIGLFITGGRA-PEYLRLNERVVEIVQEFFNDTKPVAAICHGPQILAAA-------NVVKNLKLTAYPTVAP-------------------EIRLAGGEYIETS--VD-EAIVDKNLITSPAW---------------------- +MSGKKLLMLV----GDFVE--------DYEAMVPYQLLTCVGHTVDVACP-KRKGEKVKTAVHDF--GDQ-TYTEKPGHL----FALTVDWDAVDHSHYDGLIIPGGRA-PEYLRLDQQLLAIVQSFK--DKPIASLCHGPQILVAA-------GLLKDKKCTAYTALEP-------------------DVKIAGGHWEGSCPV-D-GAVVDGNLVTAVAW---------------------- +MAAKKILMLV----GDFVE--------DYEAMSPFQILITAGHEVDTVCP-GKKGDVVKTAIHDF-EGDQ-TYTEKRGHN----FMITADFENIKADNYDALVVPGGRA-PEYLRLNEDVLKLVREFNSADKPIASICHGQQILSAA-------GILEGKSCTAYPAVKP-------------------EVEKSGGKWVAANETFS-NAVVDGKLVTAPAW---------------------- +MEAKKILMLV----GDFVE--------DYEVMVPFQALTMLGYQVDAVCP-GKKGEKVKTAVHDF-EGDQ-TYSEKPGHQ----FTLTADFDAVREEEYLGLVIPGGRA-PEYIRLNPRVIEIVRTFDAAKKPIGAICHGPQVLVAA-------GVLAGGTFTAYPACMP-------------------DIVCAGGNWAAVNDTAS-NACTSGHIVTAPAW---------------------- +ADDIKILMLA----GDYVE--------DYEIMVPYQALTMVGYTVDVVSP-DKKGDKVITAIHDF-EGAQ-TYSEKPGHH----FALTADFDKVVLDDYVGLVVPGGRM-PEYLRLDQRVLDIVKEFS--DRPIACICHGIQILTAA-------GIVKGRKVSAYPACRP-------------------EVEMAGGTYVDIP--VT-EAITDGELVTAPAW---------------------- +TEDVKLLMLA----GDYVE--------DYEIMVPYQALLMLGYKIDVVSP-GKKGDTVITAIHDF-EGAQ-TYSEKRGHN----FTLNATFEDIDTDDYIGLIIPGGRA-PEHLSMHKRVIEIVQAFA--DRPLAAICHGAQLLAAA-------NIIKGRKVSAYPACRA-------------------EVELAGATYADIA--VD-AAITDGELVTAPAW---------------------- +--MPKILIIA----GDFVE--------DYELMVPYQMLQLLGCEVDVVCP-DRRGDFIKTAIHDF-EGDQ-TYSEKPGHR----FTLNAELDEAQQSTYDGLYLPGGRS-PEYLRLDQRVLDLVKHFFEAAKPVAAICHGIQILTA--------RVMSGRRCTAYPACGP-------------------EITLAQGQYVAT--PVN-EAYVEGNLVTAPAW---------------------- +PRQNKILMIV----GDYSE--------DYEVMVPFQALSMLGFTVEAVCP-GKRGETIRTAIHEF-EGDQ-TYSEKPGHR----FALTASFATVSPEDHAGLYLAGGRA-CEYLRLDAQVLAIVRAFMTENRPVAAICHGAQLLTA--------DVVRGRRLTACPAVEP-------------------EVTAAGAHFVAT--APE-HTVIDGNLATAPAW---------------------- +RTMPKILIIA----GDATE--------DLEFFYPYQRMLEEGYETHVAAPSR---KKLSFVTHDFV-GFD-TYIERQGHS----WPADLALADVEPTEYAALVLPGGRG-PEYLRNDPDFRRVVTHFFDAAKPVAHICHAAIALAPL-------GVLKGRRTSAYPACAP-------------------DVEMAGGIFVD----GA--AVVDGNVVSARAW---------------------- +MTGQRILLIV----GDFGE--------DYEIMVPYQALRAVGHEVHAVCP-DREGETVKTAIHDF-RGDQ-TYLETRGHD----FELTHGFDEIDPSDYDALVVPGGRA-PEYLRGYDEVLDAVRHFFEADKPVASICHGPQILAAA-------GVLDGYEMTAYPAVKP-------------------EVEAAGCSWVD-------GVTTDGNLVTGQAW---------------------- +MDGKKLLMIV----GDFGE--------DYEIMVPFQALQAVGHEVDAVCP-EKEGDTVKTAVHDF-RGDQ-TYMESRGHN----FALTASFDDIDPTEYDGLVLPGGRA-PEYLRTHDEVLEAVRHFTDEDKPIAAICHAAQILAAA-------DVIEGRTCAAYSALEA-------------------DVEGAGGEYYD-------GVTTDGNLVSGRDW---------------------- +GTGKKILMLV----GDFVE--------DYEAMVPYQMLLMLEHDVATVCP-GKGGDTVATAIHDF-EGHQ-TYTEKPGHR----FAINADFASVDPADFDALIIPGGRA-PEYLRLDQAVLDIVRHFADASKPLAAICHGPQILVAA-------GILKGRECSCYPAVAP-------------------EITAAGGQYMTPGDGLD-TAHVEGNLVTAPAW---------------------- +MPAPKILMIT----GDFTE--------DYETMVPFQTLLACGYTVDAVCP-GKKGESVATAIHDF-EGDQ-TYSEKRGHN----FALNATFESVRAEDYDALVIPGGRA-PEYLRLNADVIKSIRHFFDAGKPVAAICHGAQLLAAA-------GVLKGRTCSAYPACRP-------------------EVELAGGIYADI--AIT-DAVSDGNLVTAPAW---------------------- +-MTKDILLIT----GDFGE--------DYDVMVPYQALEMVGHNVDVVCP-DKEGDRIKTSIHDF--GDQ-TYMEDRGHD----FELNATLADV-PAEYDALYLPGGRA-PEYLRTYDEVLETVRHFFDANKPVGALCHGQHILSAA-------DVVEGYEITSFPGLRS-------------------ECEAAGCAW-----V-D-EVTRDGNLVTAQGW---------------------- +MVEMKAVILV----GPEFE--------DLELFYPLIRLREEGYAVEIVGPERKA---Y---RGKH-------GIEIT---------ADKSVEEAKPEEYSCLIIPGGWA-PDRLRRDQRVVQFVKRFFETGKPVAAICHGPQLLISA-------KVLKGFKLTSASAIKD-------------------DVENAGGVYHD-----A-PVVVDRNLITSRGP---------------------- +PTSKKILMIV----GDFNE--------DLEVYFPYQAMLMNNYLIDTVSP-GKNGDFIQTAVHDL-DHLQ-SYTEKLGHL----FPITADFSKI-LKDYDALIIPGGRA-AEYQRLNKDILAIIRHFHDADKPIACICHGIQILAEA-------GILEDKKCTTVGFCEP-------------------DVRKAGGHFIDTG-M-D-GVVVDGKLVTGATW---------------------- +---MKVLMLA----GDAIE--------DYELYAPLKAMEMLGIQCDVVCP-DKKGDEIHAVLHVL-EGYQ-TYSEKPGHP----FPLPSTFADCNLDQYAGLIVPGGRF-PEYQRCDKRVLDIVRAFFRDNKPVAALCHGLQILAAA-------GVLKGRECSAFPMCQL-------------------DVENAGGKYVDFEAFSK-NVHVDDNLVSAPAY---------------------- +-MTKKILIIV----GDFVE--------FAEVTAAYKALKSLGFEVDKVCPDKK-GDTFTTAIHE--FKYQ-TYTEKLGNT----FPITADIETLNPEDYAGLWLPGGRA-PEYLRTKTRVLDIIRYFIDTQKPIVALCHGVQLLAAM-------GMMKGKRVTCIDMMTP-------------------EMKNAGCEVQKTK-NKH-DVFVDGNIIT-------------------------- +-MNSKILMIV----GDYGE--------DLEIYFPFQALTLLGFQVDAVCP-QKKQDKVKTAVHDF-RGDQ-TYMESRGHD----FTINADFPQ-DPSQYAGLVLPGGRA-PEYLRLHDEVLVVVEHFLKEKKPIVAVCHGIQLLTA--------GGLEGKKLTCYPACKF-------------------EVTKQGGVYEKVG-Y-D-EVVVDGNIVTSPAW---------------------- +MNGKKILMIV----GDFGE--------DYEIMVPFQTLQTVGHTVDAICP-DKKGDTIKTAVHDF-EGDQ-TYSEKPGHN----FSLNASFDEINPNEYDALVIPGGRA-PEYIRLNEKVLEITRHFADNNKPIASICHGLLVLSAA-------GVLKGKRCTAYPACGP-------------------DVVQAGGEYVSIP--AH-ETIVDGNLVTAPAW---------------------- +MSAKKILMFV----GDFVE--------DYEVMVPFQILTMVGHTVHAVCP-GKKGDTVRTAVHDF-VGDQ-TYMEAPGHR----FVVNFDFEKVDAKSYDALVIPGGRA-PEYLRLNQKLLEMTRHFADSKKPIAAICHGPQILAAA-------GVLKGRNVIAYPAVGP-------------------ECTVAGAKFGEVNDTAS-NALTDGNLVTAPAW---------------------- +MSERKILMIV----GDFVE--------DYEVMVPYQALEAFGFKVDTVCP-DKKGETVITAVHDF-EGFQ-TYTEKPGHK----FQVNADLYSVVLEHYDGLFVPGGRA-PEYLRLNQKVLEIVKAFFAAKKPVAAICHGLQILAA--------KVLQGTECTGYPACAP-------------------EIELAGGKYKQV--PAT-DAIVHGNLVSSPAW---------------------- +FDMKKILLIV----GDFSE--------DYEVMVPYQALQMLGIKVDVVCP-DKSGEFIKTAIHDF--GDQ-TYTEKPGHL----FRLTASFNQI-LHEYAGVYISGGRS-SEYLRLNADVLHIIHYMMGFSLPVAAICHGVQILVSA-------DVLKGKKVTAYCTVKP-------------------EIELAGGIYMDVG-V-Q-DAVVDNNLVTAATW---------------------- +MAEKKILMIV----GDFAE--------DYEVMVPFQFLCGIGHKVDAVCP-GKTGQKIATAIHDF-ETEQ-TYSEKRGHS----FVLNADFEKVAAPEYDALVLPGGRA-PEYLRLYPKVIEMVRHFFEQKKPVAAICHGIQLLTAA-------KVLSGYRLTAYPAVGP-------------------EVNLSGAEYVSVD--FE-DALLDKNLVTAPGW---------------------- +MSGKKILLLA----GDFVE--------DYEIMVPFQALQMVGHEVHAVCP-EKEGDRCKTAVHDF-RGDQ-TYLETRGHD----FALNATFADVDPADYDALVVPGGRA-PEYLRGYDEVLDAVRHFFDEGKPVAAICHGPQILAAA-------GVLDGYEMTAYPAVRA-------------------EVERAGCSWVD-------EVTVDGNLVTGQAW---------------------- +-MSKKILILA----GDFVE--------DYELMVPFQCLKMLGYSVDVVCP-NKKNEQIKTAIHDF-EGDQ-TYTEKPGHN----FTLNASFDEVDESTYDALLIPGGRA-PEYIRLNPRVIEIVQNFNKANKPIASVCHGILVLAAA-------GIIANKTCSCYPACAP-------------------DVGLSGGKWADIG--FE-RAIVDGNLVTAAAW---------------------- +-MSKKILMLA----GDFVE--------DYEVMVPYQALLSVGLEVDVICP-DKKGETIPTAIHDF-VGFQ-TYAELRGHN----FVLNKTFNEVNVEDYAGLYVCGGRA-PEYIRLNEKVLQYTRHFFDTNKPVAAICHGIQILTV--------GVLEGRTLTAYPAVGP-------------------DIALAGGTYKDI--KAT-EAITDGNLTTSPAW---------------------- +-MNKRILMLA----GDFVE--------DYELMVPYQALVSVGFHVDVVCP-GKKGEQVATAIHDF-VGFQ-TYAELRGHN----FTLNKSFDNVKLEDYAGLYITGGRA-PEYIRLDPKVLEYTKYFFEKNLPVAAICHGIQVLTA--------DVVRGKTLTCYVAVGP-------------------EVKLAGGNYKDI--PAT-EAITDGNLTTSPAW---------------------- +-MSGKILILT----GDAAE--------VLEVYYPYYRMLEEGYETDIAAPQQ---KILNTVCHDFV-DWA-TYTEKPAHR----LAANIAFADVDPSQYAGIIIPGGRA-PEFIRNDVDLPRIVRHFLEEDKPVGVICHGAQVFLALKD----STLFQGRTIKAYNASRY-------------------EVESLGATYPE----EN--LHVDGNIISGHAW---------------------- +MAGKRILMLA----GDFVE--------DYEIMVPFQMLLMVGHKVDVVSP-GKKGEQVATAIHDF-EGHQ-TYTEKRGHN----FTLNATYAGTKADDYDALVIPGGRA-PEQLSTDESVLDLIRAFVTADKPIAAVCHGPQLLAAA-------NVISGRKVSAYPACRA-------------------EMILAGADYQAI--AID-GAVTDGKLVTAPAW---------------------- +MAAKKILMLV----GDYVE--------DYEVMVPFQALLAVGHTVHAACP-DKKGDSVATAIHDF-EGQQ-TYSEKRGHN----FALNASFADLKAESYDALVIPGGRA-PEYLRLNPVVLDIVRHFFSASKPVAAICHGAQLLAA--------GVLKGRTCSAYSSAPT-------------------LNCIAAV----------------PVPCGFRAW---------------------- +ENTKKILFLT----GDFAE--------DYETMVPFQMLLMVGYEVHAVCP-DKKGETIKTAIHDF-EGDQ-TYSEKPGHN----FTLNYTFSEVNPEEYAGLVIAGGRA-PEYLRLHQGVIDLTRHFAETNKPIAAVCHGIQILTAA-------RVVEGRRLTAYPAVAP-------------------EVELAGGTYVSVE--PT-EAVVDGNLVTSPAW---------------------- +--MTKILIIT----GDAAE--------TLEVLYPYERLKEEGFEVHIGAPEV---RKLQFVVHDFV-GFD-TYTEKLGHT----WPADVALADVDPSDYAAIVIPGGRA-PEYLRNNEDAKRIVRHFFATDAPVAATCHGPLLLAAA-------GVLAGRTSSIYPELAI-------------------DVEVVGGVFEN----GG--GVVDGNLVTSRAW---------------------- +MTRVKLLLLA----GDYVE--------DYEIMVPFQALQMVGFQVDAVCP-GKKGDMCRTAVHEF-EGDQ-TYSEKPGHN----FVLNADFDAAKPESYDGLVIPGGRA-PEYLRLNPRVIEIVKHFMAAKKPVACICHGAQLLAAA-------GCVSGRTCTAYPACGP-------------------EVTAGGGNHRDVG--VE-EVVIDGNLVTAAAW---------------------- +-MSSKILLIT----GDFGE--------DYEVIVPFMLLKAIGYEVHVACPQKR-GDTVASSIHDIN-NYQ-TVTEWEGHR----ININVALDHLNPADYIALVLPGGRS-CEYLRTYPIVREVTAHFITENKPIASICRGVQILLST-------GLLKGKTMTGNFVCET-------------------EVQMAGNTYEKLN-YEG--VVVDGNIVYGVEW---------------------- +VKNTKVLLLT----GDFTE--------DYEIMVPFQTLLTFGVAADAVTP-GKRGDSIKTAVHDF-EGDQ-SYTEKPGHR----FLLNASFDSCSAADYDGLYLTGGRC-PEYLRLNPKVLALVQEFLRQGKPVAAICHGIQILTA--------GVVRGRRLTAYPAIQP-------------------EIEAAGGTYLAV--ESD-QVVCDGNLITAPAW---------------------- +GGKRSVLLLC----GDYME--------DYEAMVPFQALLAFGVSVDAACP-GKKGDVCPTAVHQS-THQQ-TYSETRGHN----FALNATFDEI-PTKYDGLVIPGGRA-PEYLAMNDSVIDLVRKFSNSGKTIASICHGQLILAAA-------DVVKGRKCTAYPPVKP-------------------VLIAAGASWIEPETM-A-ACVVDGNIITGATY---------------------- +APCKKVLMLC----GDYME--------DYEAAVPFYALAAFGVAVDCVAPGKKPGDACLTAVHE---GHD-LYTELPGHR----FAVTADFAAADASRYDALVVPGGRF-VERLSVDPLAVSLVAAFAGRRRPVVVTCHSQLLLAAA-------GAMRGVRCTAFFSMRR-------------------VVELAGGTWVEPD-PLG-LCVADGNVLSAIGW---------------------- +GADKRILFLC----GDYME--------DYEVMVPFQALQALGCHVDAVCP-DKGGDKCPTAIHDF-EGDQ-TYSEKPGHD----FALNASFDGVDASSYDALVIPGGRA-PEYLALNEKVLSLAKGFMDNGKPVASICHGQQILAA--------GVLQGRRCTAYPAVKL-------------------NVVLGGGTWLEPD-PIH-RCFTDGNLVTGAAW---------------------- +PLMKKILLIT----GDFSE--------DYEVMVPWQALNMLGFRVDVVCP-GKRGEFIKTAIHDF--GDQ-TYTEKPGHL----FRLTASFDDI-LQEYSGVYISGGRS-SEYLRLNKSVLDIVHYAMNLTLPVAAICHGPQILAAA-------GVLKGRKLTGYFTVKP-------------------EVEMAGGQWVTAA-D-D-EAIVDGNLITATTW---------------------- +RNDKKVLMPV----GDCME--------GYEVIVPFQALESLGVIVDVICSGTK-GNAITTAIQD---GCQ-IYVEMRGHS----FIIRKTFDEVDVVECQGLYITGGRV-PQYIRLKQKVLEFTRRFFNHNLPVAALCHGIRVLVAA-------GVTESRTLTCYPALSP-------------------GVRVAGGKYKEVL-PTE-TVND-------------------------------- +MNGKKILMLI----GEYSE--------EYEIFVVQQAMEAVGHTVHIICP-ETKGDRVTTSVHDF-GGVM-TWTEHKGHA----VEVDVDFDR-DTSAYDSVYIAGGRG-PEYIRTYPRVREIVREFHRDDKPIASICHGLQVLIAP-------EVIAGKKVSGLFTVEP-------------------EVALTDATYVKIG--PK-AALRDGNLVTAEGW---------------------- +MVAQNLILIV----GDYVE--------DYEAMVPYQALTMVGHSVSVISP-GKKGDKVVTAIHDF-LGEQ-TYTELKGHN----FAITADFDDVNLDNFGGLILPGGRC-SEYLRLHDNVLTIVKHFLEKKKPIAAICHGPLILTPP-------EHLKGKRISAYFACKH-------------------DIQNTGAEYVQCG-A-E-DAVVSDNIVTGVAW---------------------- +-MTRNILIIT----GDYTE--------DYETYAVKQMLELVGYNVHLVSP-GKKGDFIVTAIHDF-LGEQ-TYTELKGHR----IQLNFDFDKVDTATYNGLFLPGGRC-SEFLRLDDRVIEIVKDFNTNKKPIAAVCHGAQVLTA--------NIVSGIKCTAYPACRP-------------------EVQQAGGIYQDIA-V-D-DAVVDGHIVSGKAW---------------------- +-MTKKILIIA----GDYVE--------DYEVYSVYQSLVFVGYTVHIVSP-GKKGDFIVTAVHDF-LGEQ-TYTELKGHR----VQINFDFEQVKVADYDGFYIPGGRA-PEFLRLNERVLEITKEFNDAKKPIAAVCHGAQILTA--------NVVSGKKCTAYPACKP-------------------ELTQAGGNYQDCA-V-D-DAVVDGNIVSGKAW---------------------- +MPGKKILMLT----GEFTE--------EYEIFVFQQAMEAVGHTVHVICP-DKKGDLIKTSLHDF-EGDQ-TYTEKLGHF----FTINKTFSEAQLDQYHAVYAAGGRG-PEYIRTDKRVQAIVRHFHEKQKPIFTICHGVQILIAD-------GVVRGKKVGALGACEP-------------------EVTLAGGTYVDLS--PT-EAYVDGTMVSAKGW---------------------- +-MSQKILLIT----GDFGE--------DYEVMVPFQVLHAIGYTVHTVCPNKK-GDYVTCVVEEGGEKFQ-TYTEKIGHR----FFLNYDFDQVKPEEYYALVLAGGRA-PEYLKYDPSVLKLVKHFTDSKKSILVICHGYQILCAL-------QGIEGIVLGGPTPTSY-------------------EITNAGGIYQQIK-MED-ALLY-NNFISTPAY---------------------- +-MARRILIIT----GDGGE--------CYETLYAVHRLREAGHEPRIAAPTRKR---LHLVIHDFE-GWD-TYVERAGYR----LESDLAFDDVRVDDYDAVLVLGGRA-PEYLRHDARVLAIVRSFHERGKWVFGICHGVQVLVRA-------GLAAGARVTAYEHCRT-------------------DVELGGGEYVAD----R-QAVRHGRMVTAQTW---------------------- +-MSRKVLIVT----GDGGD--------SYEALYGCQRFLEANWEPVIAAPARRR---LHMVFHDSE-GWD-TYVERPGHA----VEARMAITAVASKDFAGIIILGGRA-PEYLRNDTSLLSLVREFADQNKCVCAIGHGIQVLVAA-------GLTKGRTVTGHPHVCV-------------------EVERGGGTYSE-----K-MAVRDGRMITAQSW---------------------- +STKAKILIIT----GDAGE--------SYECLYAKHRFEEAGYQSVIAAPSKKR---MNLVIHDFE-GWD-TYIEKPGYL----VESDIAFSEVNTQDYLAVLLLGGRA-PEFLRHDAKVIDIVREFDRDEKFIFSICHGIQILTAA-------GLVKGKTLTCYENVRF-------------------EVESCGGTFVGK----S-EAVQDGRYVTGQTW---------------------- +--MSKILVIT----GDGGE--------SYETLYAVHRFQEEGWEVAVAAPSRRR---LNLVMHDFK-GWD-TYIERRGYG----LDADLSFDEVKVDEYAAILLLGGRA-PEYLRNNAQLLELARDFDRQGKWIFAICHGVQILAAA-------GLAKGKRVTCYEHVRL-------------------EVELSGATWHT-----D-QTVRDGRVVTAQTW---------------------- +-MNRKILIVT----GDGGE--------SYETLYAVHRFQEEGDLAVIAAPSKRR---LNLVMHDFE-GWD-TYIERPGYC----LASDLTIQDVVVEEYDAILLLGGRA-PEYLRNHAALLEVVREFDRQGKWVFAICHGIQILVTA-------GLATNRTLTAYEHVRT-------------------EIEMGGGTYST-----Q-QAVRDGNMVTGQTW---------------------- +MSSKKILIIT----GDAGE--------SFEILFSAHRLREAGFVPVIAAPAVRK---LNLVIHDFE-GWD-TYVERKGYL----VESEIAFADVNSDEYEALLIPGGRA-PEYLRNDASVLQIVRDFAETGKYIFAICHGVQILVTA-------GLVNQKKIACYEHVKF-------------------EVEACGGIYVSP----D-EAVKDGRIVTGKTW---------------------- +--MARVLVLT----ADAAE--------ELDSMYPVFRLREGGHEAVVAAPTT---RAVKLVVHDFE-GWD-AYTEKPGHL----LPVDLAFGDVDPEEYDGLVIPGGRA-PEYIRTSPDVARIVHHFFDRGLPVGTICHGPQVPAAL-------GLLRGRRTAAFPPLRT-------------------DVELAGGTFVD----EP--DVVDGAMVSCRGW---------------------- +--MAKVLILT----GDAAE--------ALEVYYPLYRLKEAGHEVHVAAPTK---KTLRTVVHDFE-GWE-TFTEKPAYQ----LQADLAFAGVKSEEYDGLILPGGRA-PEYIRLNEHVPRIVGHFFEANKPIGAICHAALVFARLK------EHLKGRKLTAYTACRP-------------------DVESLGASYVT----EP--LHVDGNLVSAHAW---------------------- +--MTRILILT----GDAGE--------SQEIYYAKFRLEEEGWQVHITAPGS--GDVFLSVVHDFE-GHD-TYTEKPGYR----VTIDVGLDEVDPASYDGLVLPGGRA-PEFLCRRPQAVSVVKAFAEAGKPIAANCHGPLLLAAA-------GVTQGRTLTCYPDLEF-------------------LMSQAGARFVD----QA--VVVDGNLVSVRGW---------------------- +PKPRKVLIPI----GDATE--------VMDTLYPIFRLAEDGFEAVVAGPEARL---YHGVLHEIPDKWD-ITRESAAYH----VRATVAFKNVKPEEYAGLFVSGGRA-PEYLRYDKDLLRITRHFFEKSKPVAMVCHGIEILTAA-------GVIQGRTLTTVAKCQL-------------------DVEQGGAKYVN-----R-DHVVDGNLVSARTW---------------------- +--MPTILMPL----GDATE--------ALDTFYPFFRLQEEGYKVIVCGPEARL---YHTVLHEIP-PWD-ITQERPGYF----IRSTAAFRDLKGSDCDGMFISGGRA-PEYIRYDKDLLRLVNEVNDAGKPIASVCHGVEILTAA-------NIIQGKKVTTVAKCKL-------------------DVEQGGGTYVN-----E-EVVLAGNLVSSRTW---------------------- +MSQPKVLIVV----GDATE--------TVDTLYPYYRLIEGGYQPVVAAPEKRK---YQMVLHEVK-GWT-ITKEWEGYS----IDAEIAFKDIRPEDYAGIFFSGGRA-PEYIREDEDLLNITRWFWEKRLPMASVCHGVEIPARA-------GIVKGLRMATVAKCRF-------------------DLEICGGIYVN-----E-PCVIDRNMVSGRTY---------------------- +-MQHKVLIVI----GDATE--------TVDTLYPFLRVQEEGFQAVVAGPERRR---YNMVMHEHT-GWD-ITREWEGYK----IDADIAFRDINPAEYAGIFFSGGRA-PEYIREDPDLIRVTQYFFEKNKPIASVCHGVEIPARA-------GCVNGRRMSCVPKCRF-------------------DLEVCGGIYED-----E-PFCVDGNLVSAMYW---------------------- +FVMEKVLIVI----GDATE--------LLDTMYPYYRLQEAGFQPVVTAPEKRL---YQLVLHEIK-GWT-ITKEWEGYT----LDCDVPFAEVKEDDYAGIFFSGGRA-PEYIRYDEDLVRITQHFFDTNKPIASVCHGVEIPAYA-------DRVRGRRMATVAKCQF-------------------DLEVCGGIFVD-----E-PCVIDGNLVSGRTY---------------------- +--MFNAVIIT----GPGFQ--------DHDVVYTYYRLKEEGYNVDIATKEGKP---V---IGKYN-----VPLPMDKTA-----KPNMPFSALSVDRYDVVILTGGHA-PERVRQDKTVLAFVKAMDEAGKIVAGLCHGPWIMISA-------KVLKGRKVCSYVGIVD-------------------DMINSGADVVD-----A-EVIVDGNIITCSYY---------------------- +-MSRSAVIIT----GPGFQ--------DHDVVYTYYRLLEEGWHVDVATKEAAP---V---TGKYG-----VPLPMDKTA-----APLISFSDLDVNNYDAVILTGGHA-PDRVRQDQQVLAFVAAMADAGKVVAGLCHGPWIMVSA-------GVLKGRRACAYIGLRD-------------------DVINAGAEVVD-----S-DVIVDGNIITCSYY---------------------- +---MRAAILV----EDLFD--------ERELIYPFYRLKEMGFRVDLVGPEAKT---Y---RSKL-------GLEVK---------ADVSAEPELAEAYDVIWIPGGYA-PDRLRRSKKIVEMVRRAVERGKIVAAVCHAPWVLISA-------GVVKGRRVTGFHSIWD-------------------DLRNAGANLVE-----E-EATVDGNIITGTGP---------------------- +--MRKVLIFL----EELVE--------DVEFIYPYLRFKEEGFEVVSAAPKLGE---Y---KGKK-------GMTFR---------PDKTIKDVYHQEFDCVFIPGGYA-PDRLRRYPEVLHIVKKHYDSGKLVCAVCHGPWVLISA-------KVVKGKKVTGFFAIKD-------------------DLINAGANYTG-----K-PVEVDGNLITATDP---------------------- +--MKKIAVLI----EDNFN--------EFELIYPYYRLKEEGFESILVGPQAKV---Y---HSKV-------GLEMK---------ADFSIDEINFDEFDGVVIPGGYA-PDLLRRNEKILSFVRKMFESNKLVGAICHAGWVLISA-------KIVNGVTMTCFYSIKD-------------------DVKNAGAKYVD-----Q-SVVVDNNLITSRGP---------------------- +--MKKIAILL----EDLVE--------DVEFIYPLYRFMEEGYVVDVLAPRVGE---F---SGKK-------GMIFH---------ASKRVDPDMADYYDAVFVPGGYA-PDRFRRDKETIEFIRNMYKKGKIVAAICHGPWALISA-------KIVKGKRITAFFSIRD-------------------DIENAGAIYTG-----K-PVEVDGNIVTATDP---------------------- +--MMKVAVLI----EDLFD--------ERELIYPLYRLQELGFQVDVVGPEVKE---Y---KGKS-------GLVLK---------ATKDVRSALQEEYLVVWIPGGYA-PDRLRRSKEIIQFVRKTAERG-VVAAVCHAPWLLVSA-------GLAKGRRLTGFFSIHD-------------------DLRNAGAILVD-----A-SFVRDGNIVTGTGP---------------------- +---MRAVILV----GPMVD--------EYEVVVPYSLFKAYGFEVDIASFKAGE---V---VGKRG-----VKLELV---------PNKSFSELKADEYDAVIIAGGYA-PDKVRRDENVKRFVREMYEKGKLVLSICHGGWVLISA-------GVAKGKKVTGSKGIWD-------------------DLRNAGAEPVD-----E-PLVIDGNVVSVKTW---------------------- +---MKAVILT----YSGFQ--------DHELVYPYYRLLGAGFSVDIVADKKDE---LGRIYGIFG-----LNMPCHIVL-----SDFVKDQAKFLSEYDLLVLPGGVS-LEKLRQNKDVLNFISQWNGLGKCISSTCHGAQLLISA-------KIVKGRRISGYYSLKD-------------------DIENAGAEYVN-----E-PFVIDGNVITSPHY---------------------- +--MFSSIIIS----GALAQ--------DHEFIYPFYRLLEAESKLDVCLIGGKS---V---QGILG-----TNLPPTKDY------PVKDINQVKVNDYDLLVLPGGVA-LEKTRQDKRFIKFIADFHKADKVIACICSGVQLLISA-------KIIKGKKIAGYYSLED-------------------DIVNAGGIYTD-----Q-PAVVDSKIVTTAHY---------------------- +KNMKRAVIIT----GPNFQ--------DEEFIYPYYRLQEAGFHVDVAVKGKEA---V---KGKYG-----VPAKPT-----------VDVTELRESDYDLVVLPGGHA-PDRVRQIKEVLSFVKAMNDKNKVISSICHGPWIMISA-------GIVKGRTVSGYIAIKD-------------------DIQNAGANYVE-----E-PVVVDGNFVTSPHY---------------------- +--MKKAIIIT----GKLVQ--------DHEFIYPFYRLQEAGYSVDVAVKNKEL---V---FGQLG-----SKIIPT-----------KDIVGLNPDEYDIVVIPGGAC-LEYLRQDQDALDFIASAHKVKKTIAAICHGSQMLISA-------KIVKGKKISGYYSIKD-------------------DINNAGAMYVD-----A-PAVTDGNIVTSPHY---------------------- +MVRKRIIIIT----GPGFE--------DTEVGFPHEALLEKGFKIDVATSNNQE---V---IGKHG-----YTIKPT-----------VKYEELKSKNYDCVIIPGGHA-PDRVRQVKEILAFVREMFKTGKIISSTCHGPWVLISA-------GIMRGKKATCYPGMKD-------------------DLINAGARYKV-----K-PVVVDENIITSDHP---------------------- +-MIKRAVIIV----DNGFE--------DTEFAYPFYRLQEAGFTVEVATRGKVD---V---KGKHG-----VAANAT-----------VDADDIKEVDYDLAIVPGGRS-PDRVRQIPNVLQFLNDFDQKGKVIASTCHGPWVLVSA-------KVVSGRDVTAYPGCKD-------------------DLVNAGGNFKD-----E-AVVVDRNLVTATHY---------------------- +NINLKAVVIT----AEGFE--------DEEVIYPVIRLKEAGFEIHIATKDKKM---V---LGRLN-----FPLELLVKY----YATLVDARQLNSKDYDMVLIPGGFA-PDRMRQVPEILEFIKQMHKLKKVVSAFCHGPWVLISA-------GILKGKRATCYGGIID-------------------DLRNAGAKYVD-----R-AVVVDGNIITASHP---------------------- +SNPTRVVIIT----GPGFQ--------DHDVVYTYYRSKEEGYDISIATKDGGA---V---TGKYG-----ITVPMDKRS-----KDNINFDQLNATDFDAVILTGGHA-PDRVRQDQRVKNFLKQMVTQGKVVAGLCHGPWIMISA-------GILRDKLTCAYVGLKD-------------------DMINSGANVIE-----A-DVVVDGNIITCSYY---------------------- +LDKFKLVIIT----GPGFQ--------DHDLVYTYYRSIEEGYDVSIATKDGES---V---IGKYG-----ISVPMDKRA-----KQNITFDDLNEEKFDLVILTGGHA-PDRVRQDQRVKDFVSNMSKQEKVVAGLCHGPWIMISA-------GVMKGKLACAYVGLKD-------------------DMENSGANVIE-----A-DVVVDKNIITCSYY---------------------- +---PRIAFLVTSANAIDLKESSPTGYWAEEALKSYERFVAAGFDVVVLTPDGNKPVDPYGLERDYFASVYRTLAERPESTIRAAIDELKAASQAVMAEFDALFVPGGHGPMVDLPDNPDLSRLLRILHADGKIIASLCHGPAMLLSAPDRADGQWLFEGYRMTSYTNDEEDQNRIG----QLGMTYLADALQNAGAIFDDAPYAWASHVVVDRNLITGQNPNSTEATSEAVV----------- +---PRIAYLVSSAREIELADGTPTGYFAEEALKPYERFVAAGADVVVVTPDGREPFDPYGLEQDYFASVTRTIAARSRAEIQAAVDELDEASRALLAEFDAVFAPGGHGPMVDLADNPHVARLLTILHEKTAPIASLCHGPALLLSAPEREDGQWLFDGYRMTCFTDEEEDQTAPG----KLGLPYVDTALKNAGAVFDDGPAAWVSHVVVDRNLITGQNPASTEATADAVL----------- +---PRLLFLVSSAREIVLADGRVTGYFADEALTPYRRFADAGVEVVVATPDGRPPLDPYGLEQDFLGTVVRSIFLAGPEQIGALVADTEAAARAELAGFDAVFVPGGHGPMADLADNPDVGRLLGILQEKQATVAALCHGPAALLAAGGREDGQWLFEGYRLTCFTDEEEDQTRPG----SVGMPMVDTALKNCGAVLDDAPAAWTSHVVVDRNLVTGQNPMSADAVADAVL----------- +-TGQKLLVVLTSQDVLPTRANMKTGWYLPELVHPYNDLDGH-VELVVASPKGGEAPDPYSI-------EDSKNDEASQRFFKEKWHVWKNTLGKSAEYVGIFFV-GGHGPMFDLAVDPTSHALIREFYESNKLVSAVCHGPAALVNVK-LSDGTYMVQGQTVTGFSNAEEDAYKFTDAMP----FLLEDKLKEHGGQYEKADQLFGVKVVTSGKLITGQNPPSAGV----------------- +---AKVLIACTSGTQ--LLDGRPTGCWVEEVATPYLLWREKGIQVDICSIAGGVPWDASSTSGDFFTAQAAAFLNN--ETAAKLIKETPSVEELLADSYDALFLPGGHGIAIDG-TSDSLKQLVEQFWGAGKVV----------------------------AGFSNTEEVAVGKDKAVP----FLLEDRMKELGGDYVRG-PDWHPFAVASGKLVTGQNPQSSQRVA--------------- +-TGQKLLVVLTSQDVLPTRANMKTGWYLPELVHPYNDLDGH-VELVVASPKGGEAPDPYSIEDSKNDEASQKFFKEKVHVW----KNTQKLESFSAEYVGIFFV-GGHGPMFDLAIDPTSHALIREFYESNKLVSAVCHGPAALVNVK-LSDGTYMVHGQTVTGFSNAEEDAYKF-------------------------------------------------------------------- +-TRPKLLVVLTSQDIMPTRENFRTGWYLPEFVHPYNALAPH-VDLVVASPKGGVAPDPYSIEDSKNDGECQRFLKEQKDLW----EKTETLSSISSEFAGVFYV-GGHGPMFDLAVDQVSHSIIREFYEAGKIVSAVCHGPGALVNVK-LTNGEYLIKDNEVTGFSNAEEDAYSF-------------------------------------------------------------------- +---GKILFVLSAAREQTLADSSKTGTFLGEFYEPYMALTGAGHEVVFATDGGAAAIDPESLDERYWGDGARRA---QAQRFVERAPEVRAPLSLAADSFDGIVVPGGQGVMVDLLDNADLHALLAHFGAKHQPVGLICHAPAVLTRMRQP---HPLSGRTVTSVSSFEEFFVMGADAQVRGIGEQ-L----EDHGYEHEA-AFPGSAYAQRDCNLVTSQNPFSTDR----------------- +---GTVLMVLSAASAQTLADGSTTGVFLNEFYEPYRALLDAGYDVVLATPGGQPEFDPEGMKPSYWEDHPEALA--EAQALVT---RLPAPLSLRAETFQALLVPGGQGVMVDLLGDADLHGLLVDFGATSRPVGLVCHAPALLARLSEQ---SPFSGRRVTSVSGFEEWFVMGARAQVRGIGSG-L----EDAGFHHET-AFPGRSRAVRDCNLVTSQNPFSGTD----------------- +---GKILFVLSAAREQTLDDSSKTGTFLGEFYEPYLALTGAGHEVVFTTEGGAVAIDPESLDEKYWEDGALRA---RAQHFVERAPQVRAPLSLAADAFDGIVVPGGQGVMVDLLDNADLHALLAHFAAKHQPVGLICHAPAVLTRMRQP---NPLSRRTVTSVSSLEELFVMGAEAQVRNIGEQ-L----EDHGYEHEA-AFPGSAHALRDCNLVTSQNPFSTGR----------------- +---PSVLVVLSSRNQLDLRDDRVTGYYLNELIVPVRAMIDAGLHPVFANPDGNPITDPHSISASYFGNDEAALQ--QALTLRDSLDGLRHPLPLGLDRHAGVFFPGGHAPMGDLLVDRDVGRILRHFHDAGRPTGLLCHGPIALLAAMNP---EGFVEGLVSPAWPYAGYFSTAEESAVEEGGAA-L----REAGGEVIV-GEPWKSHVIVDRELYTAQQPASDGE----------------- +---GKVLVVMSSAHALDLRDGKTTGYYLNEFVVPYRKLVEAGYEPVIANPNGDMVMDANSNNKLFFGGDDAARA--DALKYAQGIAQLKHPKTLGTDGYVGLFIPGGHAPMVDLLKDRNLGKILVGFHDSGRPTGIICHGPIVLLSTLDP---DAFVASMTAAGWPYAGYFSTGEEQQLEG--NA-L----AEAGAHVDT-VANWHGNVVVDRELITGQQPMSAPE----------------- +---PAVLVVLSSRNELELRDGRVTGYYLNELIVPVRAMIDAGLEPVFANPAGNPVVDPHSVSAAYFGNDEEELG--KALALRDSLDGLRQPRRLGLDRYAGVFFPGGHAPMGDLLVDQDVGRTLRFFHEAGRPTGLLCHGPIALLAALDA---NGFVNALVSSGWPYAGYFSTAEEAAVEEGGAA-L----RGAGADVVV-GEAWQSHVVVDRELYTAQQPASDGE----------------- +----------------------------WEVAPPYHIFLSHGYEVDFVSPKGGFMMDPLGISSYTIK----------YEGFLDKANNSLAPKQVITDNYWGVYIGGGYGPLFDVANNKELQLIIAKIYEANGVVGSGGHGAGSFANVT-LSSGQFLVKGKRVAGFPDSTEKSKPWA---KEGSPFLVESQLNKNGAIAQNKKTLKDKYEVVDQRIVSTMFLPSA------------------- +----------------------------TEVAIPWQFLTQQQVRVVFATPKGQVAQGDRLLTFGPFAPSAIAAYETQSDGFQHPIP----YQQINSADFQGLLLPGGHDPMRSYLGSGILQQKVAAFFKAAKPIGAICHGTIVAARSQNAETGQSNLADYNTTALLATQELAAYLGRYYRTYP-ELVQTEVMTAPKQFHGPLPLKPAFVVQDRQYVSARWPGDAHLFARTFY----------- +----------------------------TESAVPWEYLTSRGVEIVFATPNGKAAAADRLITFGVFNDTAIEAYQRADTAFKHPIS----YSEIKASDYDGLILPGGHDKMKTYLESTVLQAKVAKFFAEKKIIGAICHGTVLAIRTINPQNQRSVLYDYQTTSLLKMQEMSAYLSDYYRTYP-ITVEDEVKSGSKQFQGVFSLSPAFVTEDRNYLSARWPGDAYTFSKRFY----------- +----------------------------TEAAIPWQYLTTHHVSVTFATPAGTPAAADRLLTFGPFDKAARTAYQQQSSAFTHPLS----YDNIDSADFSALLLPGGHDKIKEYLESSILRQQIVNFFAEDKLVGAICHGTVAAARAIDPQTHQSVLANFRTTSLLKIQELGAYLGTYYRTYP-QTVADEVQASSRQYRGHHPFNTSLVTVDQNYVSARWPGDAHRFAQVFY----------- +----------------------------SEVAIPWKQLTGHKHRVTFITPTGQVAVTDIMLTLGLLRADAVQAFKEQSDDFNKPLS----YGDVSAADFDALLLPGGHDKVKEYLESAVLQQLVVDFFSANKPVAAICHGVLIPARSINPGTGKSVIYDYLTTGLLKSQELAAYLGDYYLTYP-ETTEDELVAAPGQFIGGFPLNRGFFVKDRNYLSARWPGDLYSFSAEFI----------- +----------------------------TEAAVPWDYLDKQGVEIVFATPDGQMASADRLLTFGPLDSNALTNYRRASESFKRPLR----YADIDPSDFEGVLLPGGHDKMKTYLESQVLQEKVSEFFLTEKTVGAICHGTVLAARSINSKTNKSVLYDYETTSLLKVQEMGAYLKDYYRTYS-ITVEGEVKSVVRQFQGSLSMGPAFVVEDRNYVSARWPGDAHTFAKKFY----------- +----------------------------TEAAVPWNYLKEKGIDIVIATPSGKMASADRLLTFGPFEPSALKDYRSKNEAFRHPIR----YSEIDTTLFTGVLLPGGHDKMREYLESEILQKKVAEFFLAEKLIGAICHGTVLAARTIDPRTEKSVIYDYQTTSLLKSQEMGAYLNDYYRTYS-ITVEEEVKSVKNQFLGKVTMKPAFVVEDRNYISARWPGDAHTFARKFY----------- +----------------------------TEVAVPWRLLTDAGHEVVLATERAGRPAADRLLTFGQLEEEPKRFYEQGSPEFGATAG----WSDVDVTAYDGLLLPGGHAPMRQYLGSQELREQVAWFWALGRPVGAICHGVLVLARTRDPGTGRSILADRRTTCLPKYMERTAYLGRYYRTYP-AYVEDEVRSAPAQFEGPRELSHAFVVQDGTYVSARWPGDAYLFARRYL----------- +----------------------------TEVAVAWRDFYENGFQVTFSTETGKIGKADLLLSFGKLKPEAISAYEQEASEFLKPIQ----YSDITVNDYDCIYLPGGHAKMRQYLESEILREKVLSFYKQKKLIGAICHGPIILARTIDPKTGKSILYGHKISALPKILERGAYLGTYYRTYP-EYVEDEIIRVKKDFIGKSL-TNPFCVEDNQIISARWPVDVHFICKVIV----------- +----------------------------TEVAVPWRLLTDAGHEVVFATELGGAAQADRLLTFGQLEPEPKRFYGEADERFAAPTP----WAAVEASAFDGLVLPGGHAQMRQYLESVVLRRKVLDFWRMDKPVGAICHGVIVLARTTEPGTGRSVLAGRRTTCLPKYMERSAYLGRYYRTYP-EYVEDEVRAAPALFEGPRSLGPAFVVRDGNYVSARWPGDAYLFARRFD----------- +----------------------------TEVAVPWRLITNAGHRIVFATEKGGRPYADLLLTFGALEKEPKEFYSQEDDSFNNPVS----WSKVRAEEFDGLLLPGGHAPMRQYLGNASLHQFIADFWTTDRPVGAICHGVLTLARAKS-SEGVSVLHGRRTTCLPKYMEMLAYLGKYYRTYP-EYVEDEVRNAPGDFCGPVTLSAAFVVEDGRYVSARWPGDAYLLSERFM----------- +----------------------------TEVAVPWKLLTDLGHEVVFATEHGDPPAADLLLTFGQLEPEPKEFYERGEAAFRHPVA----WADLRPAAYDGLILPGGHAPMRQYLGSDVLREKIGDFWRLERPVGAICHGVLALARTLDPDTGRSVLADRRTTCLPAYMERTAYRGRYYRTYP-AYVQHEVVAAPARFEGPVELSAAFVVEDGRYLSARWPGDAYLFARRFA----------- +----------------------------TEVAVPWRLITDAGHQVVFATEHAGVPHADRLLTFGQLEPEAKKFYREDSPEFHTTHS----WSELDVTQFDGLILPGGHAPMRQYLGSASLQRQVAQFWSLDRPVGAICHGVLVLARTKDPNTNTSVLATRNTTCLPKYMERSAYLGRYYRTYP-AYVEDEVRAAPTQFHGPRELTHAFTVTDGNYLSARWPGDAYLFADRYL----------- +----------------------------SEVSIPWRILTAKRHKVVFATPSGKKGNADRMLLLGILSGDARADYDLKDQNFLKPIS----YEQIEPNAYNGILLPGGHAKMIPYLESKILQSIIVNFFDQKKPVGAICHGVLLVARSIDPNTNKSVLYNLNTTSLLKKQELLAYLGDYYLTYN-ITVEDEVKSFSSQFQGNSGISAGFTVRDQNFISARWPGDAHKFGYEFA----------- +----------------------------SEVAIPWRLLTEQQHKVTFITPNGQAARADIMLTLGLLRADAVQAYQAAEESFQQPLT----YAGVCADDFDALLLPGGHDKVKEYLESDVLQQLVVDFFRARKPVAAICHGVLLAARSIDPATGKSVIYDYNCTGLLKTQELTAYLGDYYLTYP-GTTEDELLTVPGQFLGPFPLNRGFFVKDRNYLSARWPGDLYGFSLAFI----------- +----------------------------TESSVPWRALIDAGHEVVFATPDGQPAAADRIVSFAIWVTHARDLYAQDSDAFQHPLS----FDQLDPEAFDAVVLTGGHAPMKPYLESEQVQALVAKYMLDNKPVGALCHGVLVVARARDPKTGRSVLHGRRTTALTNAQERMAWLGSYYRTYA-QTVQDEVTQAAADFEGPFLLDYGFTLRDRNYLSARYFTDSYKFADEFV----------- +----------------------------TEVSVPWKVLKENGYKILFATPNGTSGEADRMVTLGILKDDDVLLYREKSNEFLNPKK----YESIKLDSFDVLLLPGGHAKMRVYLESEFLQNLVGHTFAEGKPVAAICHGVLLAARSKNPKTKKSSLYGLKTTGLLRSQELLAWLGDYYRTYP-TPLQDEVISFKVDFQGPMPIKPGFSVLDKSYLSARWPGDAHKFAFELP----------- +----------------------------SEAGIPWKLLTARGHTIRFATPDGRPAQADRMLDLGPWDATAREAHAAQSEAFRQPVP----YDDIDAGSVDALLLPGGHAPMKVYLESPRLQAVVAAQFAADKPVAAICHGVLLAARSKRA-DGKSVLHGRRTTGLTKQQEMTAWLGSYYRTYP-TPLQTEVQSLPRDFDGPPPLGRGFTVRDGHYLSARWPGDAHAFAQALA----------- +----------------------------TEVSVPWKILKDHGYKIQFSTPTGTPGSADLMVTLGILRNEDVAVYREKSNEFLTPKK----YGSVKPDSFDVLLLPGGHAKMRTYLESEELQALVGKTFADKKPVAAICHGVLLAARSKNPKTGKSSLSGKETTGLLKSQELLAWLGDYYRTYP-TPLQDEVQSLPDHFIGPLPVKPGFTLRSENYLSARWPGDAHRFGRELP----------- +----------------------------TECVAPWLVLSQAGYDVCFATPNGNPSIADRMI-FGPLHPYILKEYHKETKRFKNPIP----YDKLNADNYRGMVIPGGHGAMQDMLHSKALQNVIADFFKKNKPIGALCTGVLAVARSMQLDPKRSVLYGKKTTAVTKLMELAGWLKNYFKPNK-DTVQDEIIQNKNDFLGPFPINRQFVVRDGNYLSARWPGDAYRFCCEFL----------- +----------------------------TEVAVPWRLLVDAGHEVVFATERGQTPAADLLLTFGKLEPEPKRFYEQQSPAFQKPIT----WEAIEPESYDGMVLPGGHAPMRQYLGSEALQAKVAAFWKLGRPVGAICHGVLVLARAKDASTGKSLLEGRRTTCLPKYMERAAYLGRYYRTYP-AYVEEEVREASGQFEGPREYGPAFVVEDGDYVSARWPGDAYLFTERFL----------- +------------------------------------------MQIVFATPDGKRAYTDYLLTFGQLAKEVVELYHEQDDAFLNPLN----YEQIEAEQFDGLLLPGGHAKMVPYLESKVLQEKVLRFWQLERPVGAICHGTIVLARTMDPRSGRSIVYEKRMTSLTKPLERTAYRGRYYRTYP-EYVQDEVTRNKANYVGPSF-NTPFVVEDGHLLTARWPKDAELFAETFI----------- +----------------------------TEVAVPWRVLTDAGHEVVFATEHGGRPRADLLLSFGQLEPEPKAFYDLEAPEYRAPIA----WSAIEPSSYDGMVLPGGHAPMRQYLGSAVLQTKVASFWALERPVGTICHGVLVLARATDPVTGRSPLAGRRTTCLPKYMERSAYRGRYYRTYP-AYVQDEVVAAGATFEGPTELGPAFVVRDGNYVSARWPGDAYLFARTFA----------- +----------------------------TEVVVPWHRCKEAGMQIVFATPDGKRAYTDYLLTFGQLAKEVVECYHGQDDAFLHPLN----YEQIEAEQFDGLLLPGGHAKMVPYLESTVLQEKVLRFWQLDRPVGAICHGTIVLTRTMDPESRRSIVYEKRMTSLIKPLERTAYRGRYYRTYP-EYVQDEVTRHKANYVGPSF-NTPFVVEDGQLLTARWPKDAELFAETFI----------- +----------------------------TEAAVSWKAFVQSGCEVTFATEYGRVAACDRLLSLHPLQEEAVVAYDEQTAAFSSPIT----YRAIEADDFDAIHLSGGHAKMRQYLDSTVLQRKVVDFVRADKLVGAVCHGVLVPARAIDPATGKSVLDGRRVTTLTKPLEKWAFVGCRYRTYW-KYTETEVRAATGAMLGETV-ESPFIVEDGRFLTGRYPLDVALYAETFV----------- +----------------------------TEVAVPWAVLSEAGHDVVFATENATTPACDKLVTFGQLKEEPKRLYAERSPAFRAPIA----WRDIDPTTFDALVLPGGHAQMKQYLASELLQSKVAAFTRTGKPFGAICHGVIVLARAKDPDTGKSVLHGRTTTCLPKYMERIAYLGRYYRTYD-AYVEDEVKEAPSDFLGPITLTCAFVVENGPYVSARWPGDAYLFARKLA----------- +----------------------------TEVAVPWRMLTDAGHEVVFATERGHMPAADLLLTFGQLAPEPRRFYGDLTEAFQKPLT----WDAVTPSDFDALLLPGGHAPMRQYLGSGALQTKVAAFWALQRPVAAICHGVLVLARTKDPATGRSVLHGTRTTCLPKYMERSAYLGRYYRTYP-AYVEEEVVAAPSHFEGPRVLAPAFVVEDGRYVSARWPGDAYLFTERFL----------- +----------------------------TEVAIPWKVLNDSQVKVVFATPTGSEAVCDHMLTLGPLDKNALKAYQEQADEFHHPIK----WDEISPDQFQGLLLPGGHAQMKEYLESSLLQKTVSHFFEINKPVGAICHGVVLAARSQRP-DGRSVLYGRKTTALLASQEMAAWMGNYYRTYP-QTVESEVTAAPKHFLGPTPLGHGFVVQDGTYLSARWPGDAHVFANAFM----------- +----------------------------TEVAIPWQILKNNGIEVVFATPNAKLAQCDIMLNLGPFNNDAKNAFEKNDRNFQTPIS----WDQIVDFKFDALLLPGGHAQVKEYLESKILQVVVSDFFEKDLPVAAICHGVVLAARSKDK-QGNSVLKDKKTTGLLKTQELLAWMKNYYRTYK-MTVEDEVKSFPKQFIGPVPLKPGFVVEDGNYISARWPGDAHAFAQALV----------- +----------------------------TEVAVPWRLLTDAGHQVVFATERAGRPAADRLLSFGQLEPEPKRFYDEADPGFAATVA----WEAVQPSEYDGLILAGGHAPMRQYLDSAVLRTKVAEFWRLERPVGAICHGVIVLARA-------GVLAERRTTCLPKYMERMAYLGRYYRTYP-AYVEDEVRATGARFSGPISTGPAFAVQDGNYLSARWPGDAYLFARRFD----------- +----------------------------TEVAVPWRLLTDAGHDVIFATERAGRPACDRLLTFGRLAEEPRRFYEERSEEFASTVG----WADLAPEAFDGLILPGGHAPMRQFLGSEVLQRQIGGFWELNRPVGAICHGVVVLARARTVAGGRSVLFHRRTTCLPKYLERSAYLGRYYRTYP-AYVEDEVRAAPTQFAGPRVLTHAFVVQDGNYLSARWPGDAYLFGRRFC----------- +----------------------------TEVAVPWRILTDAGHEVVLATERAGRPAADRLLTFGQLAEEPRRFYEQKSSEFTTTVS----WAEVDIERYDGLLLPGGHAPMRQYLGSTALHQQIARFWALGRPVGAICHGVLVLARARDLTTGRSLLADRRTTCLPAYMERTAYLGRYYRTYP-AYVEDEVRAAPTQFVGPRTLTDAFVVEDGRYLSARWPGDAYLFARRYL----------- +----------------------------TEAAVPWAALRDAGFKVRFATPGGKVALADRLT-FSWLRRAELAAYRREDPWFLAPSS----YADVDPADVTGLFVPGGHAAMRTLLEDATAQRLFARVFTRNLPVGAVCHGVLLAARAKDPATGRSVLHGRRTTALTALLELTGWLGRYYRTYR-TTVQQEVTAAPGHFLGPPLPGRGFAVRDGNYVSARWPGDCHRLAGEYL----------- +----------------------------TESAVIWDALTSSGVEVRFATPDGEPAYADRLV-FSVLRPEPLKAYQRSDPHFLRASA----YEDVEAGGIDGVLVPGGHAKVRTLLESSAAQAVAATAMSRNIPVGAVCHGVLLLARSIDPSTGRSVLYGRRTTALTAALELGGWLGDYYRTYP-TTVQAEVTAAPNDFEGPRMTDRGFTVKDRNYLSARWPGDCYRLAADYV----------- +----------------------------TEAAVPWAALRDAGYDVRFATPDGRVALADRLT-FSWLRRAELAAYRREDPRFRAPLS----YAEVDPAALTGLFVPGGHAQMRTLLEDTAAQRLFARVFLLGLPVGAVCHGVLLAARAKDPTTGRSVLHGRRTTALTALLELTAWLGGYYRTYP-ATVQAEVTAAPGHFLGPPLPGRGFTVRDGNYVSARWPGDCHRLAADYL----------- +----------------------------TESSVPWQALRNAGIEVRFATPQGLPAHADRLV-FGLLRKADLDSYKQESDAFRQPLA----YADVDTNQFEGLLIPGGHAKMHTLLESTQSQQIALQFFKAEKPVAAVCHGVLLLARTLDPDTGRSVLFGRKVTALLATMEMPAWLGRYYRTYK-QTVEAEVKTANSDFIGPLIAQTGFVVRDGQLLTARWPGDCHRFAAEWV----------- +----------------------------TESSVPWQAMRQAGIEVRFASPQGLPAYADRLV-FGLLRKADLASYAREDPSFRRPLN----YDDVDPGEFQGLLIPGGHAKMRSLLESEQARRIALHFFKTDKPVAAVCHGVLLLARTLDPDTGRSVLQGRKVTALVNTMELPAWLGRYYRTYT-QTVEAEVTAAPTDFLGPVLAQRGFVVRDGLLLTARWPGDCHRFAAEWV----------- +----------------------------TESSVPWQYLQRAGIEIRFATPEGTVAHADRLV-FGPLRRPDLDSYRAADPHFQHPLA----YADVDPTQFDGLLVPGGHADMRSLLDSEAAKRIALHFFKTGKPIASVCHGPLLFARTLDPDTGRSVLYGRKVTGLLMTMELAAWLGRYYRTYP-QTVEAEIKTVPGDFIGPPALGRGFTVRDGNLLTARWPGDCHRLATEWL----------- +----------------------------TESSVPWQALHNAGIEARFATPQGLPAYADRLV-FGPLRKADLDSYAQDSAAFLQPLA----YADVDPSQFDGLLIPGGHAKMRSLLESGQARQIALQFFKAQKPVAAVCHGVLLLARTLDPDTGRSVLFGRKVTALLATMELPAWLGRYFRTYP-QTVEAEVTAAQSDFVGPLIAQTGFVVRDGNLLTARWPGDCHRFAKEWV----------- +----------------------------TESSVPWQAMCRAGIEVRFATPLGAPAYADRLV-FGLLRDSDLQSYNAADAHFRQPLA----YADVDPEQFEGLLVPGGHAEMRSLLESDEAKRIVLHFFKAGKPVASVCHGPLLLARTLDPDSGRSVLHGRKVTALLTTMELAAWLGRYYRTYP-QTVESEIKAAPKDFSGPPALGRGFVVRDGNLLTARWPGDCHRLAAEWI----------- +----------------------------TESSVPWQAMRQAGIEVRFATPEGLPAYADRLV-FGLLRKSDLISYAREDETFLQPLA----YADVDPAQFSGLLIPGGHAQMRSLLESGQARRIARHFFKIAKPVAAICHGVLLLARTLDPDTGRPVIDGYKVTALVSTMELPAWLGRYYRTYR-QTVEAEVRAAPADFQGPWVSQHGFVVRDRQLLTARWPGDCHRFASEWL----------- +----------------------------NESSLPWQAARDAGFAAQFATPLGMPAYADRLV-FGPLPAADLARYHARDPAFCSPLP----YAGVDPAAYEGLLIPGGHARMRSLLESEEVRRIILAFFQADKPVAAVCHGPLALARCIDPASGRSVLHGRKVTALLGPMELAAWLGRYYRTYD-HSVEQEIKAAPADFLGPWLPERGFVVRDRNLLTARWPGDCHRFANEWA----------- +----------------------------TESSVPWQALHDAGIEVCFATPKGLPAYADRLV-FGPLRKEDLQCYAAADEGFKSPMA----YAEVDPEQYEGLVIPGGHAKMRSLLESEDARRIVRHFFDAQKPVAAVCHGVLLLARTLDADNVLSVLHGRKVTALLNTMELPAWLGRYYRTYS-QTVQAEVTAAVHDFLGPRFSQCGFIVHDGNLLTARWPGDCHRFAAELV----------- +----------------------------TEAAIPARLLRQAGFQVCFATADGRPALPDRMLDLGIWRKDAVLACKEELSEYRNPRL----YSDLRADDFDGLILHGGHAPMRPYLESAVLQRLVVDFMKQNKPVGAICHGVLLLARSRDE-SGISVVRHRRLTCLLRKQEMAAYLGNYYRTYP-KTTQDEVMSFPDQFEGPTALNRGFCVRDGNLITARWPGDVYSFTHAFL----------- +----------------------------SESSIPWKILKENGYEVFFATPNGKPGSADRMLTLGIWHKKARTAYNESDSHFQNPLS----YKD--PEDFEGLILPGGHAPMKEYLESKELQEFVGSFFATGKPLGAICHGVVLAARSKIPGTDRSILYGKKTTALLKSQEMAAWLGNYYRTYP-QTVEEEVKLAPKDFHGP--IKRGHAVTDGNYVSSRWPGDAHSFIISFM----------- +----------------------------TEIAVPWKLLKEWGQEVTFTTIDGQPAECDLVLRFGFFSREATKAYEEKSEEFLHPLR----WEDTDFDAYDGVWLGGGHAKVREYLESKVLQRKLANFMPKPKVLAAICHGPVLLSRTAD-EAGKSVLVGRKTSCLPYHMERDAYLGDYYRTYP-TFVQHEVESS--EVSGPETIKVPFTVQDNNYISARWPGDAWALAKLFI----------- +----------------------------TEVAVSWRVLTSNGHRVVFATESGSPGAADIMVSLDVWNKDGRSAYRDASNEFQHPIT----WAQAGLDGIDALLLPGGHARMRGYIDSGILHRLVVDAFARGVIVAAICHGVLLAARSVDPATGHSVLYGHKTTALTWAMEGLAWDRNYYRTYT-ESVQSEVTRAPTDFRVVSGMRPAFVVDDGSYVSARWPGDTHTFATVLS----------- +----------------------------TEVAVSWRVLRDNGHRVVFATESGTAGVADIMVTLDVWNKDGRRAYQDRAVEFQHPVR----WTQATVDGIDALLLPGGHARMRSYIDSGVLQRLVVDAFAGGVMVAAICHGVLLAARSIDPATGRSVLYGRRTTALTWALERTAWDPNYYRTYV-ESVQSEVTRAPTDFCVISGMRPAFVVDDGSYLSARWPGDTHTFANMLS----------- +----------------------------TEVAVSWRVLTDNGHRVIFATESGAPGVADIMVTLDIWDKNGRDAYAADSPEYRHSVS----WTAATLDGVDAVLLPGGHARMRSYIDSDILQRLVVEAFARDMIVAAICHGVLLAARSVDPNTGRSVLYGRKTTALTWAMERLAWDPDYYRTYT-ESVQSEVTRAPTDFRVTSGIRPAFVVDDGNYISARWPGDTHTFAGIVS----------- +----------------------------SEVAVSWRILITQGHRVIFATPDGQPAAADLMLSLDAWNAAARADYAASDQGFLTPLS----YPELVSTDYDGLLLPGGHARMLAYLESQPLQDFVGAFFDSGKPVAAICHGVVLAARSRSPRSGKSALYGRKTTALTWKLEQTAWDPAYYRTYG-ESVQAEVTRVPDDFLTSSGLRPAFVVTDGNYISARWPGDVHLFAATFS----------- +----------------------------SEVAVPWRVLGAAGRRLVFATPDARVAQADLMLSLDPWNRAARRAYAQSAPEFLQPIS----HADALPGAFAGLLLPGGHARMRDYLESPTVQQIAAAFFDQDKPVAAICHGVLVLARTRSPATGRSVLHGRRTTALTWTLEKKAWDGDYYRTYR-ESVQAEVARAPDDFCVPSGLRAAFIVRDGHYVSARWPGDVHAFARAFV----------- +----------------------------TEVAVSWRVLTQDGHRVIFATESGATGIADIMVSLDIWNKDGRRCYALQSVEFQHPLS----WAQATLAGVDALLLPGGHARMRSYINSQTLQGLVVEAFAGGLIVAAICHGVLLAARSIDPATGRSVLYGRRTTALTWALERRAWDPDYYRTYT-ESVQAEVTRAPTDFCVASGMRPAFVVDDGGYVSARWPGDTHTFAQVLS----------- +----------------------------TEVGVTWRVLTAAGHGVSFATPDGKAGAADIMITLDPWNKDARRAYAEASPAFRSPRR----WDELSVDGHDAIVLGGGHARMREYLESPVLQKLVADFFAADKPVAAICHGVLLAARSKR-ADGRSVLHGRKTTALSWRHERTASDRNYYRTYL-ESVEQEVIRHPGDFIVRSGLSPALVVEDGNYVSARWPGDTHCFASTFA----------- +----------------------------TEAGVSWAVLTGRGHRVSFATPEGLAGRGDIMLTLDPWDVNGREAYRAASPAFQAPLR----WDEVAGEAFDGLLLAGGHARMRPYLESSVLQALVAGFFGRGAPVGAICHGVLLAARSVK-ADGRSVLFGRKTTALTWRLERAADDGGYYRTYP-DSVQQEVTRAPADFIVDLGLRPAFFVRDAAYVSARWPGDAHGFAQAFG----------- +----------------------------TEVAVSWKVLTRSGHRVIFATESGTPGVADIMVTLDLWNSDGRNSYRDQSNEFRHPLT----WAAASLDGVDALLLPGGHARMRSYIDSDVLHRLVVAAFARGLVVAAICHGVLLAARSIDPGTGRSVLYGRKTTALTWAMERSAWDRDYYRTYT-ESVQSEVTRAPSDFRVTSGMRPAFVVDDGGYVSARWPGDTHTFATVLA----------- +----------------------------SEVAVSWKILTQRGHRVIFATPDGKPGACDIMLSLDPWNADARNAYAERDPAFMSPMC----WDQLKSEDFDGLLLGGGHARMREYLESSVLQRITAEFFADGKPVAAICHGVLLAARSKR-ADGLSVLHGRKTTSLTWSLERKASDRNYYRTYT-ESVQHEVTRAAADYIVPSGTRPAWVVRDENYVSARWPGDAHSFARTFA----------- +----------------------------TETSIPYRAFKNAGFDVHFATENGKTPECDKMLRQKLLTCQAVKAYDAATPEFTTPLS----WSS--LSSYNLIFLPGGHEKVRQLIDSPVMAQHLASYFPQTKNVAAVCHGVLALAVAKLPDKGKSILHECDTTALPGMFEGVAFLGDYYKTYG-VSVETAVRKVPKQYANS---LSPFVVEDYNYISARFPGDADLLAEKVV----------- +----------------------------TETAIPHHTFKTAGFSVYFATEHGASPACDKMLEQKLLTQATISLYKEQTEEFTSPLS----WSS--LQPYDLVFLPGGHDKVRQLIDSNIMHKHLVGYWKDKKCIGAVCHGVMLLSESMMEGEMKSIIHDCDTTALPGMFEGMAYLGDYYKTYG-ANVEASVRKRPS----------------------------------------------- +----------------------------TETAIPYATFTKAGFTVHFATESGAIPACDKMLEQKLLSQNAVNAYKDQTKEFTNPLS----WSS--LDPYDLVFLPGGHEKVRQLIDSDIMHRHLVPYWKGKKHVGAVCHGVMVLSETLTA-ENISIIHDCDTTALPGMFEGAAYLGDYYKTYG-ANVETSVRKRPKQWKHY---LQPFLVEDYNYISGRWPGDVPLLADRIV----------- +----------------------------TETAVPYTEFKKAGFEVHFATEKGKTPECDKMLKQKLLTGLAVEAYNSTQPEFQNPLS----WSS--LDTYNLIFLPGGHEKVRQLIDSHIMQRHIAAYFSSKRSVAAVCHGVMVLSKTKDM-EGKSVIHECDTTALPALFEQVAYLGDYYKTYG-ANVEEAVRKVPKQYKNS---IGAFVIEDYNYISARFPGDAKLLAEKTV----------- +----------------------------TETAVPYTAFKKAGFEVQFATETGRAPECDKMLQQKLLTKSVVDVYNQKTPEFQKPLS----WTS--LDAYNLVFLPGGHEKVRQLIDSPVIQKHLSSYFPASKTVAAVCHGVMVLSETKGP-DGKSVIHECVTTALPARFEQVAFLGDYYKTYG-ADVEKSVRKQSTQYKNS---MSPFVVLDYNYVSARFPPDAQLLAEKII----------- +----------------------------TETAIPWRVFRDAGLTVSFATEAGKAPACDKMLTGTLLNQAAKAAYEIKDTAFRQPLS----WTA--LVDFDLVFLPGGHERVRQLLDSAEAQKVLVEYFETSKVVAAICHGTQVLANAT--RDGKSVLHECDTTGLPGAMEQTVFLGDYYKTYG-ASVQTAVTKKPSQFKSS---SAPFIVEDYNYLSGRFPPDSEALAKRAV----------- +----------------------------TETAVAFTIFKDAGFDVQFATETGNAPKCDRMLYGRLLSKKAVEQYHAKDPAAQKPLA----WSD--LLHYDLLYFPGGHEKVRQTIDSASLQRHVAEYFPQRKTVAAICHGVQTLSSATLP-DGKSVLHDATTTALPGAMESGIFLGDYYKTYG-KNVETIVKKRPKQYKNS---PRPFIHEDYNYISGRFPPDTALLAKRTV----------- +----------------------------TETALPWSVFRAANIETYFATETGNPPKCDMMLEGSLLPAAAKTAYREVSAEFTKPLS----WTA--LKEYDVVFLPGGHEKVSAIIDSKSVHKLLAEYFPLPKVLAAICHGVMVLSSAE--GDGKSLLDGVTTTGLPHMMEQGIFLGDYYKTYG-ASVETSVTKCGAVWKGS---LSPFVVEDYHYVSARFPPDAEAIANRVV----------- +----------------------------TETAIPWKIFKDAGFDVSFATESGNPPKCDKMLSGAVLSKAAKRAYRDNTDAFQRPLA----WTD--LDGYDLVFLPGGHEKVRQILDSARVHDLLARYFPQRKALAAICHGVQVLALST--GDGRSVIHDTVTTALPAYMEQGIYLGDYYKTYG-ASVEEIVKKRRAQFKNS---LGPFVVEDYNYLSARYPPDAEALAKRAV----------- +----------------------------TEAAIPWKVFNEAGFDITFATETGKQPVCDRMLTGALLPQVAKEAYKTRDSRVQNPIS----WTD--LEDYDLVFLPGGHDKVQQIIDSPRVHELLAAYFPKTKSLVAICHGVQVLATAS--SSSKSVIHDVQTTALPGFMEQSIYLGDYYKTYG-ASVQEIVTKRPSLFKNS---PSPFVVEDYNYLSGRFPPDAELLAQKAV----------- +----------------------------TETAIPWQVFQNAGFEVSFATEKGASPQCDKMLSGTLLNKAGKKAYGATTPNFQNPLA----WND--LADYDLVFLPGGHEKVRQIIDSPRVHELLASYFPERKSVAAICHGVQVLAMTS--TEGKSVLHDVKTTALPAFMEQGIFLGDYYKTYG-ASVENVIKTKKAQFASS---PSPYVVTIPKTQQI------------------------- +----------------------------TETAVPWKILGEAGLEITFATEHGKAPVCDRMLTGALLAKAGKRAYAQETAAFQQPRS----WTD--LRDYDCVVLPGGHDKIRQIIDSERIHQLLAEYFPLRKCIAAICHGVQVLAASEYTVEGKSVLADVRTTALQGFHEQFIYLGDYYKTYG-HPVQEIVTKRAEQFQRS---FTPFVVEDYNYVSARYPPDAEEFGKKVV----------- +----------------------------TETAIPWQVFRDSGFEITFATEAGTSPKCDKMLSGTLLNKAAKKVYKSDISGFQKPLA----WKD--LSDYDLVFLPGGHDKVRQVIDSPRVHELLAAYFPQRKSIAAICHGVQILAMAS--TEGKSVLHDVQTTALPALMEQGIFLGDYYKTYG-APVEEIVRKRRRQFASS---PTPFVALDYNYLSARFPPDAKTLAKKAV----------- +----------------------------TETAIPWQVFENAGFEVFFATETGQSPRCDRMLSGTLLNGAARTAYAATTPNFQRPLS----WID--LEDYDLVFLPGGHEKVRQIIDSPRVHYLLKSYFPNSKCLAAICHGVQVLAMAS--TEGRSILHDVHTTALPAVMEQGIFLGDYYKTYG-ASVEDIVKENKKQFASS---PRPFVVQDYNYLSARFPPDAELLAKKAV----------- +----------------------------TETAIPWKVFKDAGFDVYFATEDGNTPKCDKMLSGTLLNKAAKRAYEDSTEAFKKPLA----WKD--LEDYDLVFLPGGHEKVRQIMDSARVHEVLASYFPKPKSLAAICHGVQVLAMSS--TDGKSVMHDAVTTALPAYMEESIYLGDYYKTYG-AAVEEVVKKRRAQFKNS---PSPFVVEDYNYLSARFPPDSEALAKRVV----------- +----------------------------TEAAIPFEYLTNKGWDIEIITQDGKEPQCDRMISSTVMKPPAKAAYQ-SSTSFKNPKA----WTT--LLDYDVLILPGGHDKVKQIIENESLRLHLAEFFPLKKVCGAICHGVMVLAWAKDP-AGKSLLYDRKTTTLPEHLEKMAYLGDYYRTYP-G-TAGLVQE-PQYVAGP---ECAHVVCDERYISARWPGDAHKWSETIF----------- +----------------------------TEAAIPYKYLTEKGWVIDIVTESGKSPKADMMLTASLLKAAAKDAYTNSATSFKEPKA----WND--LTQYDVVIIPGGHEKVRQIIESRHLRSLLSEIWPY--------------MVTKDE-TGNSILYDRKMTTLPEHLERLAHIGDYYRTYP-G-TAALVQECPQYLPGL------------------------------------------ +----------------------------TETAVPYAMFKSTDYEIKFATETGKAPQCDKMLEQKLLKKDAIALYKQASDEMRHPLS----WTD--LDAFDVVVLPGGHDKMRQIIDSAAVHKLLLEYFPQRKVVAAICHGVMVLANARDA-EGRSVIRDCLTTTLPAKMEQAAYLGDYYKTYG-ADVEQSVIKAP-QFKSS---PGPFVVEDYNYISARYPGDAQVFAEEIV----------- +----------------------------TEVTVPYVAFKNAGFDVQFATETGKAPECDLLVEQKILKASVVQDYAKA------------------------------------------------------------------------A-NGQSIISDCSTTTLPARFEQVAYLGDYYKIYG-ADVEDSVKKCPNQYKSS---LSPFVVEDYNYISARFPADAEEMAEKMV----------- +----------------------------TEAAVPFKAFKDAGFQVSVATETGKPPECDLMLNGPILKPAAVALYKEQTPEWKTPAA----WTS--LSSYDMVFIPGGQDKIRQVIDSEDVHKLLVEYFPQNKAIGAVCHGVMTLAISKRG-DGKSAIHDVETTTLPGMYEEVSYLGDYYKTYG-VTMEAVVRKAPAQFKQS---PMPFIVEEYNYISGRYAVDMDILSEKLV----------- +----------------------------TETAVPYTAFRDAGFEVSFATEKGLSPLCDRMLESLA-SRSVKLKYASASHEWKNALS----WSA--LQAFSLVFFPGGQDHIRQLLDSEVVHKLLQEYFPTANVIGAICHGVKVLADTNTD-GGRSVLHGCITAVLPSLFEQAAFMGDYCKVYG-GDLEHAVQKKK-HLKTS---PLPFVVEDFNYVSGRCQADAQKLSERLV----------- +----------------------------TEATVPYTAFKDAGFDVQFATENGNAPACDLLLEQKILKGSVLQDYAKASDECKQPLS----WTA--LDPFSLVFLPGGHDKVVQIMDSAAVHSLLLDYFPKTKAVGAICHGVLVLANAKDA-QGHSVLRECTTATLPARFEQVAYLGDYYKTYG-ADVEVSVKKVPKQYKCS---LSPFVVEDHNYISARFPGDTEKMAQRMV----------- +----------------------------TEVAVPYQAFKDAAFDVNFATETGKTPRCDRMLEQKLLAASVMKLYESESAEMQQPLS----WTA--LDDFDVVHIPGGHDKVRQLMDNAVVQKLFADYFPKKKVVGAICHGPLVLCNAKGE-DGNSVLYHCTTTALPACFESVAFLGDYYKTYG-ANVETSMKKVP-QFKSS---NRPFVVEDYNYISARFPPDAAKYSEMVV----------- +----------------------------TEVAVPYKAFKDAGFHVNFATETGNLPRCDRLLEQKFLAAPVLKIYDAKSPEMQNPLS----WSD--LDVFDVVHIPGGHDKVRQLMDSTTAQKLLADYFPKRKVVSAICHGPLLLCNTKGE-DGNSVLYHCNTTALPAFFEASSYLGDYYKTYG-ANVETSMRKAP-QFKSS---NKPFVVEDYNYVSARFPPDAAKMAEMTV----------- +----------------------------TETAVPWAAFKAAGYDISFVTESGKVPRCDKMVEQKLLTKDVVATYKTQSNEMAHPLS----WSA--LDPYDLVVFPGGHDKVRQVIESPIVHKLMLDYFPKRKVVGAVCHGVMVLSETKDA-NGRSVIYECATTALPTKYEQAAYLGDYYKTFG-HNVQESVTKAP-QFKLT---PGPFVVEDYNYISARWPGDAELFAEEII----------- +----------------------------TETAVAYTIFKEAGFEVQFATETGNTPKCDRMISGKLLSKDAIKKYEQQDPAARSPFS----WSD--IAEYDLIYFPGGHDKVRQAIDSESLQKHIVSYFPQRKVVSAVCHGVQTLSTATLP-DGKSVLHDATTTALPGAMESGIFLGDYYKTYG-KNVETIVRKTPKQYKNS---PAPFIVEDYNYISGRFPPDTEILAKRAV----------- +----------------------------TETAVPYAAFKEAGFTVRFATGTGKTPECDMMMEGKLLTAAVVNQYKAESEEARHPLS----WAA--LDEYNLVLLPGGHDKVRQIIDSKEVHKLMLDYFPKNKAVGAICHGVMVLSSAKGS-DGKSVIHECTTTTLPGLFESSVYLGDYYKTYG-ANTEDSVRSSDKQFKGSAASQYSFVVNDYNYVSARWPGDADLFAKTLV----------- +----------------------------TETAVPYSAFKEAGFNVSFATEKGKSTQCDRMLQQLLLARPVIQQYNTASEEWQHPLA----WSA--LDAFDLVFLPGGHEKVRQIIDSEAVHRLLVDFFPKAKAVGAVCHGVMVLSEAKDA-EGRSVLHGCTTTTLPARFEQLAFLGDYYKTYG-ADVEDLVRKEP-HLKSS---PTPFVVEDFNYISARFPGDVRLMFEKLV----------- +----------------------------SEAAVPFTAFKEAGFRITFATETGNVPQCDKMLEQAILKRSVIAQYKTASAEWTSPAS----WSD--LSAYDLVFLPGGHDKVRQVIDADAVHALLATYFPQKTAVGAVCHGVMVLSETKSS-DGTSVLHGVTTTALPTRFEQLAFLGDYYKTYG-ANVEESVTKVP-DFKKS---PAPFVVEDYNYISARFPGDVDLLGEKLV----------- +-----------------------------ETAVPYTVFREAGFEVNFATETGTSPKCDKMLQQTIFTQSVLRQYSAASEEWKHALR----WST--LDAFDAVFLPGGQEKIRQLIDSPVVHKLLADYFPQGKAVGAICYGVKVLAQAKGP-DGRSILYGRTTTTLPALFEKAAFMGDYFKVYG-ADVEASVVKVP-CLKSS---LAPFVVEDFNYASGRHPGDAQLLAERLV----------- +----------------------------TETCGPYTAFKAAGFDVSFATEAGKSPQCDKMLEQRLLSSSIVKQYRVDSEEWKNPLS----WSD--LDAFNLVFLPGGHDKVRQIIDSDRVHKLLADYFPKNKAVGAVCHGVMVLSESKHP-DGSSVIRDCVTTALPARFEQVAFLGDYYKTYG-ANVEDSVRKVP-QFKNS---PSPFVVEDYNYVTARFPGDVELLSQKLV----------- +----------------------------TETCGPYTAFKEAGFDVSFATEAGKSPQCDKMLEQRLLSSSIVKNYRVESEEWKNPLS----WTD--LDAFDLVFLPGGHDKVTQVIDSERVHQLLVDFFPKKKAVGAVCHGVMVLSETKYP-DGSSVIRDCVTTALPARFEQLAFLGDYYKTYG-ANVEDSVRKVP-QFKNS---PSPFVVEDYNYVTARFPGDVELLSQKLV----------- +----------------------------TETCVPYTAFKNAGFDVKFATEAGKSPQCDKMLEQRLLTSFNVKRYHAESEEWRNPLS----WSD--LDAFNLAFFPGGHDKVRQVIDSERVHKLVSDFFPGTKAVGAVCHGVMVLSESKHP-DGNSVIRDCATTTLPARFEQLAFLGDYYKTYG-ADVEVLVRKEP-LLKIS---PSPFVVEDFNYITARYPGDAELLSQKLV----------- +----------------------------TETAGPYTAFKAAGFEVSFVTENGKAPECDRMLQQKLLTKGVIDLYNKQSDEHQHPLS----WSA--LDPYDLVFLPGGHEKVRQVIDSDIVHRLLVDYFPKKKALAAVCHGVMVLSESKDA-NGKSVIHQATTTTLPARFEQVAFLGDYYKTYG-ANVETCVRKA-KQFKNS---PTPFVVEDYNYISARFPGDVDLFSEKIV----------- +----------------------------TETAVPFTHFKEAGFEITFATEKGESPKCDRMLEQVLLTKSVVSQYNDASPEWASPLS----WMT--LSAYDLVFLPGGHDKVTQVIDSARVHELIAAYFPLKKAIGAVCHGVMVLSETCRA-DGKSVLNGAITTALPTRFEQLAFLGDYYKTYG-ANVEEAVTKKP-DFKNS---PAPFVVEDFNYISARFPGDVQLMSEKLV----------- +----------------------------TETAIPYTTFQKAGFEVHFATETGKAPACDKMLRQALLTSSVVQKYDSASHECKHPRA----WTA--LDSYDIVFLPGGHEKVRQIIDSAAVQKLLADYYPKNKAIGAVCHGVMALSKAKGE-DGKSVLHGCVTTALPARFEQLAYLGDYYKTYG-ADVEASQRGT----------GRSFVVHDFNYVSARYPGDAEPMAEKLV----------- +----------------------------TEVAIPWKKFRDSGWEITFATENGKVAKADRLLSATFLSKAAAAAYRDESEAHKNPLA----WSM--LVPYDAVLLPGGHDKIRQYLDSESLHLLLREYWPLSRVVGAICHGVVALSNATHPPKGPSLLHDVETSTLPYWMEQVAWFGGYYKTYG-ASCASDVSKVKQQYKGP---QSPFAHVDYHYISARFPRDSWLFAEKMV----------- +----------------------------TEAAIPWSLLKTADCSVTFATEHGIVACADLLLTARVLTKKAKETYNEASPEFQKPLS----WSD--ILEYDIVLLPGGHDKIRQYLESESLHRQLEKFLPCHKVLGAICHGVLSLAFAKCPVKSLLAEHNLQTTTLPRWMEATAWFGYYYRTYP-D-CYVDA---AGQYIGP---QK------------------------------------- +----------------------------TELFIPALHFLKCGFSLTFATNDGEPAQADKLLEGRVWSEEGRMAYEQQLEAFQKPDS----WGS--VLDYDAIILPGGHDKIRAFLESKTLQAHLRTFWPFPRVIGAICHGSLALAFTELPS--QSVLRGVCSATLPRWMERAAWGGGYYRTYG-PWCADDI---SAKYVGP---TSPFVCVDWRYVSARFPGDAKLFAQKVE----------- +----------------------------TEVATPFTVFEQAGFEVSFATETGKVPECDRMLKGKLLPAVAVEQHAAKTATYQRPVS----WTS--LKDYDLVFLPGGHDKMKQYITSGLLHKHLAEYMPLSKAAAAVCHGVQTLATAD--ASGNSVIYDFVTTSLTNFMENSAFLGDYYKTFG-YNVEEAVKMRPKQYKSS---LSPFVVHDYNYLSGRFPGDADRLAKETV----------- +----------------------------TQVCESWQYFLKQGFIVHFATLTGNVAQADTQLSSWFITAETCKLYDRTISEFLKPLS----LSS--LNTYDLVLIPGGKDPVLDFVHSSRLSALLADYIPLNHALGAIAQGAIAIHRAVPN-------LQIKSTTTPLYMERTSYP--P--AYA---------SMPDKYEGP----SHWVYSDYFYASGRHSGDVELLCKALR----------- +----------------------------TEVAQPWQRFIKHGMFVYFVAPHGRVPQADQQLSSWIVDAETREIYGRTTDEFLKPFD----LFD--FTDYDLVYIPGGTDPVYELMEMSRLTELLAQYIPLYHVLAATAQGALAVVKAAGN-------LDLKTTTTPLYLERTSYP--E--AYL---------SAPEKYVGP----KEWVYEDYFYISARHSGDIGLLCKEIF----------- +----------------------------TQVCDPWQFFVKEGFMVNFATLTGIVAQADRLLSSWFITYKTKDIYERTTKEFLSPSN----MSD--FENFDLVYVPGGQDPVLELVESPRLSSLLADYIPLTRVLATMAQGAIAVQRAAPN-------LEIKSTTTPLYMERASYP--P--AYT---------YTPSKYVGP----AHWVYSDFFYASGRYSGDVELLCKALR----------- +----------------------------TQVCDSWHYFLKQGYMVHFATLTGNVAQADRLLGSWFFTAETCRLYERTTTEFLKPLS----LSS--FNTYDLVLIPGGQDPVLEFVQCSRLSFLLSDYIPLNHVLGTIAQGAIAVHCAAPN-------LQIKSTTTPLYMERTSYP--S--AYA---------STPDKYKGP----SHWIYSDYFYASGRYSGDVSLLCKALR----------- +----------------------------TEVAVPYHAFKDAAFDVNFATETGKTPRCDRMLEQKLLAASVMKLHESESAEMQQPLS----WTA--LDEFDVVHIPGGHDKVRQLMDNAVVQKLFADYFPKKKVVGAICHGPLVLCNAKGD-DGNSVLYPCTTTALPACFESVAFLGDYYKTYG-ANVETSMKKVP-QFKSS---NRPFVIEDYNYISARFPPDAAKYSEMMV----------- +----------------------------EQVCLPWRYFTDRGFLVEFVFPRPRTARPDSYTCGSIMSKEAMDIYSITLEEFIEPKH----YTD--FLDFDVVLITGGRNEMRQMLTDPSLHSKLKPYLSLSKILGTIAQGTLPIYMSDPE-------TPLKSTTIPVWMERTNSESSY--PYA---------ASPDKYFGP---RSVFTMEDHYFISGRCNRDILPLSTGIY----------- +----------------------------EQVCLPWRYFTDRGFVVEFVIAEPRPPKPNSYMTSHVLSKEILDIYSVTLNEFNNPKC----YRS--FDNFSAVFITGGRNPVREMLEDPLLHASLVPYIHSIKVLGAISQGAAAIYLAEPN-------INMKTTTIPAWMERSNSDSTY--PYA---------ATPDKYVGP---RVAFTYQDYYYISGRSNKDIGELSKKMY----------- +----------------------------EQVCLPWRYFTDRGFMVEFVFPKPRVAKPDSYTTGTLMSKDTMDIYSITLDEFIQPKF----YKD--FLDFDVVLITGGRNEMRQMLMDPLLHSKLKPYLTLSKILGTIAQGALPIYINNPG-------TTLHATTIPVWMERANSNSSY--SYA---------ASPDNYSGP---RAVFTIEDNYYISGRCNIDILPLSIGLY----------- +----------------------------EQVCFVWRSLTDSGFMVEFIIPHNLTPQPNDVLSGLLKPKSAKEIYSVTLNEFTHPNV----LHS--LTKFDVLFITGGAGQVEEMITDPLLHSLLVPYLRLSKIVCAVSQGVRAIYAADPT-------IQLKATTIPVWMERSSLI--A--PYT---------APPDRYVGP---KKKFIYVDYYCVTGRCNNDSIMLARMVV----------- +----------------FIISGDKHGFWLPEVVGPYRVLHDAGYEIELASSTGKPGYPRGRLEEAQLRWL-------DSSPLKQQLSEPYDIETRDSRDYLAVYYAGGAGPMFDLTAHAPAKVLTEAIYKAGGIIAADCHGTVALLNLQN-DSGHRLISNRRITGKANS--------------------------------------------------------------------------- +--AKHVLLVLISHSDL--GGVRPTGFYVDEAAHPWQVFRRMGFTVGLASIAGGVPPQAGRHPGDPV----QEQFL-HDADISRQLVNTRALAQVNANRYDAVLFVGGHGVMWDFPNNSVVNAVGRNIWERGGIVPWAC--------------------------------------------------------------------------------------------------------- +-AGKRALIIATN-QAVLETTGDATGVMASEMTHPYYRFLDAGMQVDLASIKGGKPVDPQTINWLLKTPEDDRFLADP--AFLAKVENSMRIDDVDFTQYDIIFMAGGFGAAYDLGYSPVLAKISEAYYASEPVIGGVCHGVLGLINAKD-RDGKSLIAGRRMTGVTDKQIKELGIIEIT---------------------------------------------------------------- +-TGKKALVIGTN-HGILETTGDPTGVQISELSHPYYTFLDAGMSVDVGSISGGEPIDPQTLSRMIISPLDKRYLDDP--SLQAKMRNSIPIGDIDFTQYDTVFLAGGWGAAYDLGYSVELGKISEAYYSEKTIIGGVCHGVLGLIKALD-KNGNLLIAGRNMTGVTDKQITELGIT------------------------------------------------------------------- +-----VLLICTSCSSV--GNRKDTGVWLSEVAVPYYIFRNGGYDVTLCSLAGGEIPDQAGLTGRFLADEAAM---------LQLRESVAVSSVKQPAAYDCIFLAGGQGAMGDMPHSSELATVVGEAAMHGRLVAAVCHGPAGLLGAKD-ADGKPLVAGKTIACFSQAEEEKTGSMPF-------QLESKLKELGANVCC-ADINEENALRDGVLVTGQNHNSVARVAK-------------- +LTGKRIAILVT----DGFE--------QVELTGPKEALEQAGATVEILSAEEGQ-----------VKG---WNHDKPA--DDFKID--RTFKAANASDYHGVVLPGGVQNS-DTIIDTDAQKIVKGIEAAGKPVAVICHGGWLLIS-------AGLVKGKTLTSFETLKDDL-------------------VNAGAKWVDQE------VVVDGTLISSR------------------------ +AMAKKILMLVG----DYVE--------DYEVMVPFQALQMVGHTVHAVCPDKRAGE--------SVAGA-QTYSEKPG--HRFTVN--ASFSDVDPAAYDALVVPGGRA-P-EYLLNPRVLDIVRHFGGAGKPIATICHGAQLLSA-------AGVLKGRACSAYPACGPEV-------------------TAAGGAYQDIPVD---QAHTDGNLVTAP------------------------ +-MSKTLLMLVG----DYAE--------DYETMVPFQALLAVGYTVHAVCPGKKSGD--------TVAGA-QTYTEKRG--HNFTLN--HDFDGVDPAAYDGLVIPGGRA-P-EYLLNEKVLDIVRAFDKAAKPIAAVCHGAQILAA-------AGVLKGRTCSAYPACAPEV-------------------RLAGGTYADIAVD---QAHTDGHLVTAP------------------------ +MAAKKILMLVG----DYAE--------DYETMVPFQTLLAVGHLVDAVCPGKAAGD--------RIAGD-QTYSEKRG--HNFTLN--AAFETASADAYDGLVIPGGRA-P-EYLLNPAVLALVRAFDDAAKPIAAVCHGAQLLAA-------AGVLKGRRVSAYPACRPEV-------------------ELAGGEYADIAID---DAVTDGHLITAP------------------------ +MAAKKVLMIVG----DYAE--------DYETMVPFQILLAVGHAVDAVCPGKTTGQ--------QVRGD-QTYSEKRG--HNFTLN--ADFAAARVVDYDALVIPGGRA-P-EYLLDAAVLDLVRAFDSAAKPIAAICHGAQLLAA-------AGILKGKRVSAYPACAPEV-------------------TLAGGLYADIAID---GAVTDGHLVTAP------------------------ +MAVKKILMLAG----DFVE--------DYEIMVPFQMLLMVGHQVDVVCPGKKAGD--------FVAGF-QTYTEKRG--HNFTLN--ADFDKVDTAAYDALVVPGGRA-P-EYILDPRVLEIVKEMAAAGKPIASVCHGQQVLVA-------AGVLKGRTCTAYPAVRPDV-------------------EATGGRWCEVNATF-TNACVDGNIVTAP------------------------ +MAVKKILFLVG----DFVE--------DYEVMVPFQMLLMVGHDVHAVCPGKKAGQ--------QVRGD-QTYSEKPG--HNFTLN--ADFDAVNTADYDALVIPGGRA-P-EYILNPRVVEIVREMAAAKKPIASVCHGQQLLVT-------AGVVKGLTCTAYPAVKPDI-------------------EGAGGTWCEVNDTF-TNACVDGNVVTAP------------------------ +MAKKKILMLAG----DFVE--------DYEIMVPYQMLLMVGHDVDVVSPGKKPGD--------VIAGH-QTYTEKRG--HNFMIN--ADFDAVDCAAYDGLVVPGGRS-P-EYLLNPRVIEIIREMDGAKKPIAAICHGQQMLVS-------AGILKGRSCTAYPAVKPDV-------------------VDAGGVWCEPNATA-TNAFVDGNLVTGP------------------------ +MAVKKILMLVG----DFVE--------DYEVMVPYQMLLMVGHTVHAVCPDKKAGD--------KVIGY-QTYSEKPG--HFFGLN--QDFDKVRAADYDALVIPGGRA-P-EYILNPRVIEIVKEMAAAKKPIAAICHGPLILAA-------AGVTKGCTCMAYPAVGPDV-------------------EMTGGTYVAPNETF-SNAVVDGNLVTAP------------------------ +GMAAKILLVTG----DAAE--------SLEVLYPYQRLREEGYEVHIAAPSRKT-----------LRGF-DTYTEKPG--YTIPAD--LAFSEVDPGQYTALVIPGGRA-P-EYLNDPELRKICKAFFDADKPVAQICHGPLLTAA-------VGGLSGRRVTAYPALEPDM-------------------QAAGADYQDAE------VVVDGTLISSR------------------------ +--MTRVLMIAG----DAAE--------TLETIYPYQRLVEEGYEVHVGAPTKKK-----------IQGF-DTHTEKLG--YLWPAD--IAFADVRPEEYTALVIPGGRA-P-EYLYDTDVRRIVDHFVTTRKLIAFQCHGPLILAA-------SGALKGRHTTGWPTIAADL-------------------EAAGAQYIDEE------VVIDDNLVSGL------------------------ +MSAKKILLLAG----DYVE--------DYEIMVPFQALTMVGHIVHAVCPQKKQGD--------IVRGD-QTYSEKVG--HNFTLN--ATFADIKASDYDALLIPGGRA-P-EYLLNPDIITIVKHFAETNKPIAAVCHGAQILTA-------AGVVSGKSCSAYPAVAPEI-------------------NNTGGCWVDIAVT---DAYVDGNLVTAP------------------------ +MASKKILMLVG----DFVE--------DYEVMVPFQALLMVGHTVHAVCPNKKSGE--------SVRGD-QTYSEKPG--HNFVLN--ATFAEVSAADYDALVIPGGRA-P-EYLLNPEVIQIVQHFAQTNKPLAAICHGAQLLSA-------AGVLAGKRCSAYPACGPEV-------------------AAAGGEYVDLAVD---DALIDGNLVTAP------------------------ +MSAKKILMLVG----DYAE--------DYETMVPFQALLMVGHTVHAVCPGKQTGQ--------SVRGD-QTYSEKPG--HNFALN--FDFAQVRAEDYDALLVPGGRA-P-EYLLDERVLELVRNFATANKPIAAVCHGAQLLAA-------AGVLAGRSCSAYPACAPEV-------------------RLAGGEYVDVPLD---QAHVDGNLVTAP------------------------ +TVAKKILMLAG----DFAE--------DYETMVPFQALQMVGHTVHAVCPDKKAGD--------HCAGD-QTYTEKRG--HNFTLN--ATFADIDPARYDALVIPGGRA-P-EYLLNARVLEIVRHFAQANKPIAAVCHGAQLLAA-------AGVLEGRTCSAYPACAPEV-------------------RLAGGKYADIPVD---QAHTDGNLVTAP------------------------ +-MGKRILIIAG----DFVE--------DYELMVPFQALSAVGHTVHVVAPDKRAGD--------AIRGD-QTYTEKRG--HNFTLN--ADFATIEPSAYDALLIPGGRA-P-EYLLNERVISAVRHFAEAKKPIAAVCHGAQLLAA-------AGVIEGKRISAYPACAPEV-------------------TLAGGSYQSLDWP---DAITDGNFVTAP------------------------ +MKAKKILLLAG----DFVE--------DYEIMVPFQALQAVGHTVHAVCPDKKAGD--------QIAGQ-QTYSEKRG--HNFTLN--ATFDSVKVEDYDALVIPGGRA-P-EYLMDDKVLAMVRHFAQADKPIAAICHGAQLLAG-------AKVLEGRLCSAYPACRAEV-------------------ELAGGRYADIAID---GAVTDRNLVTAP------------------------ +-MSKRILIIAG----DFVE--------DYELMVPFQALAAVGHTVHVVAPDKRTGD--------IIRGD-QTYTEKRG--HNFTLN--ADFTLVNPAQYDALLVPGGRA-P-EYLLNDQVIACVRHFTEAKKPIAAVCHGAQLLAA-------ANVIEGRRIAAYPACAPEV-------------------KLAGAQYVALDWP---DAITDDNFVTAP------------------------ +MSAKKVLMITG----DFTE--------DYETMVPFQTLGAVGHDVHAVCPDKTAGD--------TVAGD-QTYTEKRG--HYFTLN--ATFSDINPADYDALVIPGGRA-P-EYLLNPAVLDMVRHFFTENKPVAAICHGAQLLSA-------AGVLEGRACSAYPACAPEV-------------------TMSGGTFADIDVA---DAVTDGNLVTAP------------------------ +--MAKILLLAG----DFVE--------VLEVFVPFQALQAFGFQVDAVTPGKKRGD--------TVRGD-QTYTEKRG--HNFTLN--FDFDEALTRTYDGLVIPGGRA-P-EYLLNPQVLQIVRHFFERDAPVAAICHGIQILSA-------AGVLKGRTSTAYPAVAPEV-------------------RLAGGEFSEVEAT---EVVVQGNLITSP------------------------ +ITMKKILLLAG----DYVE--------DYEVMVPFQMLLMLGYEVHAVCPGKKAGD--------FVRGD-QTYSEKRG--HNFAIN--YDFDKVDVADYAGLVVPGGRA-P-EYLLNERVLEIVREFDAAGKPIAAICHGPQLLVS-------AGILKGRTCTCYAAVKPDV-------------------VAAGATWHDFNATA-SNAVVDGNLVTAP------------------------ +-MSKKILMLVG----DYVE--------DYEVMVPFQALLMAGYTVHAVCPGKKAGD--------VVRGD-QTYSEKRG--HNFALN--GTFDEVDEKNYDALVIPGGRA-P-EYILNKRVLEIVKHFANENKPIAAICHGPQVLVA-------AGVLSGRECAAYPAVSPDI-------------------EAAGGKYISLDMD---KAHVDGNLVTAP------------------------ +-MSKKILMLVG----DYVE--------DYEVMVPFQALTMLGYAVEAVCPDKKAGD--------FVRGD-QTYSEKRG--HNFTLN--KDFAAVDTADYVGLVVPGGRA-P-EYILNARVLEIVREFDAAGKPIAAICHGPLVLVT-------AGVLKGKSCAAYPACGPDV-------------------TCAGGKYADIALD---KAHVDGNLVTAP------------------------ +-MPKTILILVG----DYVE--------DYEAMVPFQTFLTLGYTVHAICPGKKAGD--------FVKGD-QTYSEKRG--HNFVIN--MAFDDVTDARYDGIYIPGGRA-P-EYLMNPRVVAIVQHFGARNKPIASICHGPQILAA-------AGLLKGRQCTAYPALEIDC-------------------IIAGASWVGKKPD---EACVDGNLVTSP------------------------ +-MAKKILFLVG----DYVE--------DYEVMVPFQALAALGYQVHAVCPGKKAGE--------FVRGD-QTYSEKRG--HNFTLN--YSFDEVNEHEYDALVIPGGRA-P-EYILNPRVLEITRHFFTANKPVAAICHGLQVLAA-------AGVLNGRRCTAYAAVGPDL-------------------PLIGAEYHELPAD---QAITDGNLVTAP------------------------ +GNPKKILFLTG----DYAE--------DYETMVPFQMLQMVGYEVHAVCPDKKKGD--------MVRGD-QTYSEKRG--HNFQLN--YSFDEVNPADYEGFVVAGGRA-P-EYLLNEKVLELVRYFMDNNKPLAAICHAIQILTV-------AGVVQGRKLTAYPAVGPEI-------------------GLAGGTYESVAID---DVVVDGNLVTSP------------------------ +MAAKNILMLVG----DYAE--------DYETMVPFQALQMVGHRVHAVCPDKKAGD--------TVRGD-QTYSEKPG--HNFALN--FDFTAVRAEDYDALVIPGGRA-P-EYLLNEQVLALVRAFDEAGKPIAAVCHGAQLLAA-------AGVLKGRACSAYPACAPEV-------------------KLAGGDYVDIPVD---QAHTEGNLVSAP------------------------ +DMAKKLLMLVG----DYAE--------DYETMVPFQTLLAVGHTVHAVCPGKKAGD--------SVAGA-QTYSEKRG--HNFALN--HDFEQVEADAYDGLVIPGGRA-P-EYLLNERVLEIVRQFDRAGKPIAAVCHGAQLLAA-------AGILQGRTCSAYPACAPEV-------------------RLAGGTYAEVAMD---QAHTDGNLVTAP------------------------ +MSAKKILMLVG----DYAE--------DYETMVPFQTLLAVGHSVDAVCPNKKAGD--------SIAGD-QTYSEKRG--HNFALN--ADFEKARVQDYDALLIPGGRA-P-EYLLNEDVIRLVRDFNDADKPIAAVCHGAQILAA-------ADILKDRRVSAYPACAPEV-------------------RLAGGTYAEIAID---DACIDGNLVTAP------------------------ +-MAKRILFIVG----DYVE--------DYEVMVPFQALAAVGLTVKAVCPGKKPGD--------SVAGA-QTYSEKRG--HNFALN--ADFAATKVEDFDALVIPGGRA-P-EYLLDAAVIALVQGFVAAGKPIAAICHGPQLLAA-------AGVLTGKTCSAYPACRPEV-------------------ELAGGTYADIAID---GAVTDGLLVTAP------------------------ +TMSKKLLMLVG----DYAE--------DYETMVPFQTLLAVGHTVHAVCPDKKAGD--------TVAGA-QTYSEKRG--HNFTLN--HDFAKVEPQHYDGLVIPGGRA-P-EYLLDERVLDIVRHFDQAGKPIAAVCHGAQLLAA-------AGILKGRTCSAYPACAPEV-------------------RLAGGTYAEIGID---QAHTDGNLVTAP------------------------ +----------------------------------------------------------------------------------------FAFDDIKVDDYQAILVPGGWAPLRRYP---QVIEMVQTMDKSQKVIGQICHAGWVLI-----SA--NILNGVKVTSTPGIKD-------DM------------TNAGAEWF------DEAVVADRHIVSSRRPP--------------------- +----------------------------------------------------------------------------------------KGIDDVQASDFDALFIPGGFSPLRADD---RFVNFVDYFIENDKPLLAICHGPQLLI-----QT--NKLKGRTVTGFTSIRP-------DL------------KNAGATVK------DEEVVVDRNIVTSRTPD--------------------- +-------------------------------------------------------------------------------------------------------IPGGFSPLRIHQ---GCLNLVRSLYEKNKIIAAICHGPQVLI-----SA--GIVRGKSITSYQAARD-------DL------------INAGANYE------DSPVVVDGNIITSRVPD--------------------- +-----------------------------------------------------------------------------------------------------MLIPGGFSPLREDD---RFGEFAKVFIQDGKPVFAICHGPQVLI-----DT--DLLKGVDITGYKSIRN-------DL------------KNAGANFK------DEEVVISKNIVTSREPK--------------------- +-----------------------------------------------------------------------------------------------------MLIPGGFSPLRTDE---RYVTLTKEFLTSEKPVFAICHGPQLFI-----QT--GLTKELTLTGYDSIRP-------DL------------TYAGATVK------DEPVVIDDHLITSRNPD--------------------- +----------------------------------------------------------------------------------------VSIADAKPENYDALLIPGGFSPLRGDG---RYGTFTKYFTQNDVPTFAICHGPLLLV-----DT--DDLNGRTITGVINVRK-------DL------------SNAGAHVV------DESVVIDNNIVTSRVPD--------------------- +----------------------------------------------------------------------------------------IAFKAVNPADYDILVISGGKGPMRLDK---DALEIVKHFFKENKPVAAICHGPQVLV-----SA--GVIKGRKATCWIGIRD-------DI------------IAAGALYE------DSEVVVDRNLVSSRNPG--------------------- +----------------------------------------------------------------------------------------IAFKDVNPEDYDILVISGGKGPMRLDK---DALEITKHFFEKNKPVAAICHGPQVLV-----SA--GVIKGRKATCWIGIRD-------DI------------IAAGALYE------DSEVVIDGNFVSSRSPD--------------------- +----------------------------------------------------------------------------------------LGIDEAKPEDFDALLIPGGFSPLRADD---RFGEFAKAFVQAGKPVFAICHGPQVLI-----DT--DLLKGVDITGYRSIRN-------DL------------KNAGANYK------DEEVVVSCNIVTSRTPD--------------------- +----------------------------------------------------------------------------------------LSASQISLDDVVALIIPGGNAPMRIQK---NMVDLVKRASYQKKIIAAICHGGLMLV-----EA--DIVRNRKVTGYRSIAT-------DL------------KNAGGQYL------DKEVVVDGNLVTS------------------------- +----------------------------------------------------------------------------------------VDWADIDVDDYECVVVPNGRSPLVTKE---EAVALVAKFAAKGEVVGSINQGHLVLA-----AA--GLLKGKRCAGRVPMRV-------IS------------NLTGAVGVE-----PEGAVTDGKLVTAASWP--------------------- +------------------------------------------------------------------------------------------MDHVHYDDYDLLIIPGGVNALRHHP---KALEIIQSFSNQAKPIAVICHAPLVLI-----NA--ERIQAEQLTSHKNIRL-------DL------------ENAGAIWV------DEAVHTCNTLISSRSSE--------------------- +-------------------------------------------------------------------------------------------------------MPGGLNPLRTDE---QAIAFIRAFSTAQKPVAAICHGPWLLL-----ES--DLVRDRQITSWPSVKT-------DL------------INAGARWQ------DAEVVVDGQLITSRKPD--------------------- +-----------------------------------------------------------------------------------------------------MVIPGGYSPMRRCS---DTVNFVKEMCQQQKIIAAICHGPWMMA-----SS--CDLKGKRVTSFFSIKD-------DL------------INAGAQYV------DEEVVIDGNLITSRTPN--------------------- +-----------------------------------------------------------------------------------------------------MVLPGGQNSIRTDV---DAQQLVKDIDASGKPLAVICNGGWLLI-----SA--GLVKGKTLTSFSSLKD-------DL------------VNAGAKWV------DQAVVTDGTLISSRQPD--------------------- +------------------------------------------------------------------------------------------------------MLPVDLNPLRTDK---QALAFSRAFAAAKKPVAAICHGPCLLL-----ES--DLLRDRDVSSWPSVKT-------DL------------INAGARWQ------DAEVVVDGQLITSRMPD--------------------- +----------------------------------------------------------------------------------------------------MLVIPGGVNALRIDE---DGRRLVKEFATAGKPVGAICHGPWVLI-----DA--DVAKGKTMTSYISIRP-------DL------------ENAGVSWV------DKELFRCPVLLTSRNPN--------------------- +---------------------------------------------------------------------------------------------VTPAEFDALLLPGGHSPLRGDN---RFVTFTRDFVNSGKPVFAICHGPQLLI-----SA--DVIRGRKLTAVKPIII-------DV------------KNAGAEFY------DQEVVVDKQLVTSRTPD--------------------- +------------------------------------------------------------------------------------------------------LIPGGFSPLRADQ---RFVSFAKSFMDDKKPVFAICHGPQLLI-----TA--KALDGRSATGYTSIQV-------DL------------ENAGVQFK------DEEVVVCQQLVTSRTPD--------------------- +----------------------------------------------------------------------------------------VAADAANAADYDALVIPGGVNALRVEK---AAVEFTRAFFEAGKPVASICHGPWILI-----EA--GVADGRKLTSYHTLAT-------DL------------KNAGATWV------DEEVVVDQGLVTSRNPG--------------------- +------------------------------------------------------------------------------------------------------MLPGGINPLRIEP---KALAFIKSIYKQKKVLAAICHAPWLLI-----ET--GLIKGKKVTSYKSIKT-------DV------------INAGGKWE------DSEVVTDQGLITSRNPG--------------------- +----------------------------------------------------------------------------------------LTLDQAKAEDFDGLVLPGGFNALRVVP---AAQAFVKAFEDAQKPIAVICHGPWLMV-----SA--GLVRGRTLTSWPTLQD-------DI------------RNAGGTWV------DREVVTDRNWVSSRKPD--------------------- +----------------------------------------------------------------------------------------KALGDISIDDFDMLIIPGGSSPMREIP---EVVDFTINFYNTGKTVASICHGPQLLA-----AT--GILNGVNATGVSDIQE-------EL------------EAAGAFYI------NEAVVVDNNLITSRDPD--------------------- +----------------------------------------------------------------------------------------RTFKAANASDYHGVVLPGGQNSIRIDT---DAQKLVKDIEGSGKPVAVICHGGWLLI-----SA--GLVKGKTLTSFKTLKD-------DL------------VNAGAKWV------DQEVVTDGTLISSRQPD--------------------- +----------------------------------------------------------------------------------------KTFSEVKADDFDGLVVPGGVGALRGSD---EAIGFIRAFFDQKKPVAAICHAPWTLI-----EA--GVLKGRTLTSYPTLKV-------DI------------ENAGGAWT------NEEVVVDKGLVTSRDPD--------------------- +-------------NGTLFS----TGNHPVETLLPMYHLHQAGFAFDIATPSGLMVKFEHWMPCAAIQG----LYQHYLPQFRRPRRLREVLSTAGEQDYAGVFIPGGHGALIGLPFDADVAETIRWTMREDRYLIAICHGPAAFLSLA---LGENPLRGYALCAFPDSADRAIGYMPRLQAMGMTLVNT----------AISG----QVHQDRKLLSGDSPFAA------------------- +--------------------------------MPMYHLDKAGFSFDIATLSGNPVKFEWWMPRQEVNG----LYSKYQSSFRQPLKLSDVIELGEDSDYIGVFIPGGHGALMGLPDSQEVKAVLQWAMKQNKFIISLCHGPAAFLAVG---D-DPLFAGYKIVAFPDEMDASIGYMPQLQAIGFELLNT----------GISG----QVFQDRKMLTGDSPLAG------------------- +----------------------------PELLYPYYRLKEEGYEVHLIGPEKDKVYTGK-----------------H--GYPMKS--THASKDVKAEDYDAVIIPGGYS--PDHMRCNDTINFVKEMDKLQKTIAAICHGPWIMASA-------CNLKGKKLQAFS----------------------------------------------------------------------------- +----------------------------PELLYPYYRLKEEGYEVHLIGPEKDKVYTGK-----------------H--GYPMKS--THASKDVKAKDYDAVIVPGGYS--PDYMRCNDTINFVKEMDKTAKAHSGYLPRPLDYGFR-------LQFKGKE---------------------------------------------------------------------------------- +----------------------------AELIYPFYRLKEAGHESVIISL-GKRPIEGK-----------------F--GYVIKP--SFKIDEVSSNDYDGVIVPGGTN--PDYLRNKNVLNFVHTLDQQHKLVGAICHAGWV---------------------------------------------------------------------------------------------------- +----------------------------LEVWFPYYRLKEAGLEVNFVAAEAKKEYHSK-----------------E--GYPCIS--EIAAAEADAGDYDCMVVPGGFA--PDFMRNADVIKFANDMVNAGKVITAICHGGWL---------------------------------------------------------------------------------------------------- +----------------------------LELWYPYYRLREEGFETFTIGPEQGKTYNSK-----------------H--GYPCKA--EVGIDDVNHEDLAALIIPGGFA--PDYWRDKRFLDLVKNMYQSGMYTRIAFRTT------------------------------------------------------------------------------------------------------ +-------------------------------TSPKEALENAGFETEVIGDTAKHELVGK-----------------H--GEKVTV--DVSIADAKPENYDALLIPGGFS--PDHLRDGRYGTFTKYFTQNDVPTFAICHGPLLLVDT-------DDLKGRTITGVI----------------------------------------------------------------------------- +----------------------------SELTSPMKALKDAGHQVEIIEDMAGNTITGE-----------------H--GDTQKV--DLGIDDANFDDYDALLLPGGGS--PDALRDDRFNDFVKRFLLANKPVFAICHGPQFFIQT-------GLAS------------------------------------------------------------------------------------- +----------------------------EEVIYPYYRFKEAGYDVKVVGPEADKEYKGK-----------------F--GVVFKS--DLSASQISLDDVVALIIPGGNA--PDKMRQKNMVDLVKRASYQQKIIAAICHGGLMLVEA-------DIVRGRKVTGYR----------------------------------------------------------------------------- +----------------------------YETMVPFQFLTGLGYTVHAVCPNGEQTYSEK-----------------R--GHNFAI--NYDFDAVNTEDYIGLVIPGGRA--PEYLRNERVIEIVREFDRVKKPIAAVCHGAQLLAAA-------DILKDRLCSAYP----------------------------------------------------------------------------- +----------------------------YENMVPFQALLAMGHEVDAVCPDGDQTYTEK-----------------R--GHNFVL--NASFADINVEDYDALYLPGGRA--PEYLRNAKVIAMIQHFANTDKPIASVCHGPQMLTAA-------GVLKGKKKYLLI----------------------------------------------------------------------------- +-----------------------------------------GHTVHAVCPDGDQTYSEK-----------------P--GHLFAL--NFDFAKVDATDYDALLVPGGRA--PEYLRNEKVLDLVRAFDKAGKPIAAVCHGAQLLAAA-------GILEGRECSAYP----------------------------------------------------------------------------- +----------------------------YEVMVPFQAFQALGYQVDAVCPDGAQTYSEK-----------------P--GHRFTL--NASFDQIEMEKYDGLVIPGGRA--PEYLRNSKLLALVRYFFEAEKPVACICHGIQILSTA-------GVLEGYKCACYN----------------------------------------------------------------------------- +----------------------------YETMVPFQALQMIGHQVAAVCPDGAQTYSEK-----------------P--GHRFVL--NADFTSVKEADYDALLIPGGRA--PEYLRNAEVLKLVQAFDAARKPIAAVCHGPQLLAAA-------RHIKRPHLQRL------------------------------------------------------------------------------ +----------------------------YETMVPFQALQMIGHQVDAVCPDGAQTYSEK-----------------P--GHRFVL--NADFASVNEANYDALVIPGGRA--PEYLRYESVIKLVQAFDAANKPIAAVCHGPQLLAAA-------GVLKGRTCSAYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQALMLLGYDVEISAPNNLDTYIEL-----------------T--GHRIPV--DIATKDVNVEDYIGLVIPGGRA--PEYIRYNEVVEVTKKFFALNKPVAAICHGSQLLAAC-------GVLSGRKVTSYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQALMMLGYQVDIAAPNNLDTYIEL-----------------T--GHRIPV--DIAASDVNPDDYIGLVIPGGRA--PEYIRYDETIKLVQAFFAENKPVAAVCHGTQLLAAA-------DVLTGHTVTSYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQSLQMLGYQVDIAAPNTLDTYIEL-----------------P--GHRIPV--DVSVSEVKADDYAGLVVPGGRA--PEYIRYDETIKLVQDFFAAGKPVAVICHGLQLLAAA-------KVLEGYKVTSYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQALMMLGYQVDVAAPNNLDTYIEL-----------------T--GHRIPV--DIATVDVNPDDYIGLVIPGGRA--PEYIRYDESIAIVQAFFTADKPVAAVCHGTQLLAAA-------GVLSDRNVTSYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQSLQMLGYKVDISAPNTLDTYIEL-----------------P--GHHISV--DIPASEVNVNEYEGLVVPGGRA--PEYIRYDDTLKLVQDFFKAGKPVAVICHGLQLLAAA-------KVLEGYRVTSYP----------------------------------------------------------------------------- +----------------------------YEVKVPQQALMMLGYQVDVAVPNGLDTYVEL-----------------T--GHRIPV--DIAAKDAKAEDYVGLVVPGGRA--PEYIRYDEALKLVQDFFAAGKPVAAICHGTQLLAPA-------KVLAGKTVTSYP----------------------------------------------------------------------------- +----------------------------YETMVPFQALQMIGHQVDAVCPDGAQTYSEK-----------------P--GHRFVL--NADFSAAREQDYDALLIPGGRA--PEYLRNDDVLKLVQAFDAARKPIAAVCHGPQLLAAA-------GILKGRTCSAYP----------------------------------------------------------------------------- +----------------------------YETMVPFQALQMIGHQVDAVCPDGAQTYSEK-----------------P--GHRFVL--NADFTTVKEQDYDALLIPGGRA--PEYLRNAQVIKLVQAFDAARKPIAAVCHGPQLLAAA-------GVLKGRTCSAYP----------------------------------------------------------------------------- +----------------------------YEVMVPFQALQMLGHQVDAVCPDGAQTYSEK-----------------P--GHRFVL--NADFAAARVEDYDALLVPGGRA--PEYLRNEQVIKRVQDFDAAGKPIAAVCHGPQLLAAA-------GILRDRTCSAYP----------------------------------------------------------------------------- +----------------------------YETMVPFQALQMLGYQVDAVCPDGAQTYSEK-----------------P--GHRFIL--NADFAPVKEQDYDALLIPGGRA--PEYLRNDRVLKLVQEFNAAYKPIAAVCHGPQLLAAA-------GVLKGRTCSAYP----------------------------------------------------------------------------- +----------------------------AELVEPQRALAAEGAQVDVISQKRGEIQHVD-----------------K--GERVKV--DRTFDDAREGDYDAVVLPGGVN--GDAIRVPAAREFVTAAVGAGKPVAAICHGGG----------------------------------------------------------------------------------------------------- +------------------------GTEESEYTITYDVLVRGGVSVRSALVPPC---DSAYVTC--SRGV-------R-------IVPDISLPCPAVREYDALIIPGGAKGAETISSSSDVHALIKHMHDAGKVVGAICAGSLAIQA-------AHLAPGAKITSHPSV------------------KSQLE--SDYDYR------EERVVVSDRLITSRGPGTTFEFAL-------------- +------------------------GAEEMEAVITIDVLRRAGVEVTVAGLTGK---N--PVKC--ARQT-------V-------ITPEVALADMKDHKFDAVILPGGQPGSNSLAASDEVGAVLRSQHEAGRIVAAICAAPIAFKS-------HGIASGSLVTSHPCV------------------REKMTD-GGYKYS------EDRVVAVGNVVTSRGPGTAFEFAL-------------- +------------------------GSEEIEAVCIIDTLVRAGAKVTVSSVMGR---DDRVITA--SRGV-------K-------IQADSNIDDVKDEDFDMIILPGGMPGATHLRDCATLTEMLKKQRQAKQWYGAICAAPSVLES-------HGLLEGEKATGYPNA------------------ALEITN----RVD------GPRVVISNNVITSMGPGSALEFAL-------------- +------------------------GSEPIEAVITIDVLRRSGADVTVASVEK-----QLRVDA--CHGV-------K-------IVADALVSDCRDAVFDLIALPGGMPGATNLKESEVLESIVKKQASAGRLYAAVCASPAVLGS-------WGLLKGLKATCYPSF------------------MEQLAP-ACAATV------ESRVQQDGIVVTSRGPGTTMEFAV-------------- +------------------------GTEPMEAVITIDVIRRSGADVTVASVEK-----ELRVDA--CHGV-------K-------IVADALVADCKNTVFDLIALPGGMPGASNFKDCGALESLVKKQAADGRLYAAVCASPAVLGS-------WGLLKGLKATCYPSF------------------MEQLQ--SCATAV------ESRVQQDGKVVTSRGPGSTMEFAV-------------- +------------------------GSEEIETVTAVDTLVRAGAHVTLASVEK-----ELQVTA--SRGV-------K-------LVADLLISDARSKQFDAVVLPGGMPGAEHLRDSQPLMDLVKRHLETGKLIGAICAAPAVLAS-------HHLLNDVKATCYPAP------------------NFRAKL-TSHAHI------DDPVVRDGQFITSQGPGTAMAFSL-------------- +------------------------GFEEIELTGPVWYFKELGAEVEIVSPKFN---PALVFPE--MSNT-------HVMAIVGWIKFDRTADQIKVSDYDAVFIPGGAWNPDNLRYDKDVIKFIQDFNKSGKLIAAICHAPVVLAS-------ADILKGRKLTGYWNI------------------QVDLKN-AGGTIL------EQPVVTDGNIITSRHPIDVADFSR-------------- +------------------------GFEEIELLGPVWYFKQLGATIDIVAPKFN---PALMYPE--MSKT-------HIMAIVGWIKFDRTADQIKVSDYDAVFIPGGAWNPDNLRYDKDVIRFIRDFNQSGKLIAAICHAPVVLAS-------ADILKGRKLTGYWNI------------------QTDLKN-AGGIVS------DEPVVTDGNLITSRHPIDVADFSR-------------- +------------------------GVEELEILVPLNYLKESGAEVFVVSPKKP---NFVKMPE--IRST-------HIMTVSGWIKIDKFLEDVSVEDFDGLVLPGGSWNPDFLRTNTNAHTLLQAFVETNKPLASLCHGPLILVN-------AGLLKGRKVTGYWSI------------------MKDLEN-AGATVI------DQPLVTDGQLLTSRFPYDLPRLMN-------------- +------------------------GVEEIELTTVLHFFRSRGATVDLIAPKKP---SYLQIPA--IRET-------HILTIAGWIAFDKVLDDAEPEIYDAVVIPGGAWNPDTLRADPKVLAFVRAVAQNEKIVASICHGPWILAD-------AGLLVGRRATAWWAM------------------KNDLTN-AGAIFV------DEPVVVDGKIISSRAPTDLVAFVN-------------- +------------------------GVEETEISIPRKWFEERGATCHLVSPNHI---EYIQFPE--IAKT-------HVLAISGWIPIDARIEEVSVEDYDAVYVPGGAWNPDQLRVNPAVLKYLQDFQSTGKPVGALCHGSQVFLS-------AKLLKGRKATGYWNI------------------MEDMAN-AGAHVL------DEPVVVDGNVITSRFIYDIPQFVK-------------- +------------------------GVEELEILVPLNYLREVGANVTIVAPRKK---IYLKIPE--NRRT-------HIMTVSGWLKIDKYIDEVSFDDFDGLVLPGGAWNPDFLRTDVEAQNLVREIVNSNKPLATICHGPLVLIN-------SGLVKDRKITGYWAI------------------MKDLEN-AGAKVY------DQPVVIDGNLISSRFPYDLPRLMN-------------- +------------------------GVEELEILVPLNYLREIGADVVVVSPRKI---DYLKFPE--IRRT-------HIMTVSGWLKIDKYIDEVSPNDFDGLVLPGGAWNPDFLRTDIEAQELVKGIMSANKPLATICHGPLVLIN-------SDLVKGRKMTGYWAI------------------MKDLEN-AGAKVY------DQPVVIDGNLITSRFPYDLPRLMV-------------- +------------------------GFEEVEALTPADVLRRAGYEVFLVSTTGAPN----------V-KGAH--------DIVVKTD--VFMDDVEVDSATLLLLPGGIPGATNLLANEKVKKLVAQFHSRDKWLAAICAAPMILGEM-------HLLNGKKATCYPGFEK-------HLY--------------GATWLIHP------RSQMEKLLPEKALA--------------------- +------------------------GFEETEAIGTIDVLKRGGVDIKIVSVTGDTF----------V-ESAH--------GVGIKAD--IYLPDVKAEEADALILPGGMPGAENLKKDMTVRSLVDAMYAKGGLVAAICAAPMVLGDL-------GLLKNKKATCYPGFES-------EMT--------------GAVATGQP------VEQDGNIITGKG----------------------- +------------------------GFEQVELTEPMKALKDAGATVEIVSPRQGEI----------QGHFDK--------GDAFKVD--RAVSAADASAYAGLMLPGGAHNPDTLRVDEDALKFVRAFFDAGKPVAAICHAPWILIDA-------GVVEGRKLTSYKTIRT-------DLRN------------AGARWWTKR------WSWTKAWSPAAIPC--------------------- +------------------------GIEAVELTDPWDAVTGAGHTAELLSPESGEV----------QLHLDK--------AETRTVD--TTVADASVDDYDALVLPGGVANPDALRMDEKSVAFIKAFVDSGKPVAAICHAPWTLVEA-------GVLSGKRVTSWPSLQT-------DIRN------------AGGDWVDEE------VVEDGNLITSRNPL--------------------- +------------------------GIEKVELTEPWKAVTDAGFTAELLSPESGEV----------QLHLDK--------ADTQKVD--IEVSKANVDGYAALVLPGGVANPDALRLDEDAVTFVKNFVASGKPVAAICHAPWVLVEA-------DVARGKRLASFPSLQT-------DIRN------------AGGEWVDET------VVVDGNLITSRNPL--------------------- +------------------------GIERVELTDPWDAVTGAGHSATLLSTEPGTV----------QTHLDK--------AETRPVD--GLVKDASVDDFDALVLPGGVANPDALRMDADAVAFIKAFVESGKPVAAICHAPWTLIEA-------GVLKGRTLASWPSLQT-------DLRN------------AGATWKDEE------VVVDGNLITSRNPL--------------------- +------------------------GFEQVELTGPKEALEQAGATVEILSSQDGNV----------KGHDKP--------ADDFPVD--GTFKAANASNYDGIVLPGGVQNSDTIRLDSDAQQIVKDASASGKPLAVICHGGWLLISA-------GLVKGKTMTSFKTLKD-------DLVN------------AGANWVDQE------VVTDGKLISSRQPI--------------------- +------------------------GFEQVELTGPKEALEQAGATVEILSAEEGKV----------KGHDKP--------ADDFKID--GTFKAANASDYHGVVLPGGVQNSDTIRIDSDAQKIVKDIEASGKPVAVICHGSWLLISA-------GLVKGKTLTSFKTLKD-------DLVN------------AGAKWVDQE------VVTDGKLISSRQPI--------------------- +------------------------GVEEIELTEPWQAVLDAGWNPRLVSTQPGRV----------RAHFAP--------GGTYGVD--HVLAGDTAEAFDALVLPGGVANPDALRMNELAVGFTRSFFEAGKPVAAICHAPWTLVEA-------DVVRGRTLTSWPSLAT-------DIRN------------AGGTWVDEK------VHVPATLVTSRKPL--------------------- +------------------------GVEEVELTEPWKAALEAGWNPQLVSTEPGQV----------QAHLDK--------AGRFTVD--HVLAGDTSDAFDALVLPGGVANPDALRMNERAVGFIRSFFDAGKPVAAICHAPWTLVEA-------EVVRGRTLTSWPSLAT-------DIRN------------AGGTWVDEE------VHVPGTLVTSRKPL--------------------- +------------------------GVEEVELTWPWKAVLGAGWTPQLVSTKPGKV----------QAHLDK--------AGTYEVD--RVITGRTDESFDALVLPGGVANPDALRMNASAVDFTRGFFEAGRPVAAICHAPWLLVEA-------GVVRGRTLTSWPSLAT-------DIRN------------AGGTWVDEQ------VHIASPLITSRKPL--------------------- +------------------------GVEEIELTEPWKAVLEAGWNPQLVSTEPGRI----------QAHLDK--------AGTYPVD--RVLSNHTAESFDALVLPGGVANPDALRMNEPAVDFIRDFIASAKPVAAICHAPWLLVEA-------DAVRSRTLTSWPSLAT-------DIRN------------AGGTWVDEA------VQVPATLVTSRKPL--------------------- +------------------------GVEEIELTDPWKAVLDAGWEARLVSTEPGTV----------QAHLDK--------AGTHPVD--DVLDNSSAGDFDALVLPGGVANPDALRVNEDAVAFTRGFFEAGKPVAAICHAPWTLVEA-------DVLRGRTLTSWPSVAT-------DIRN------------AGGTWVDEE------VRVPATLVTSRKPL--------------------- +------------------------GVEQVELVKPWQAVSGSGGEPRLVSTRPGRV----------QAHLDK--------ADTFPVD--QVVAGASVDDFGALVLPGGVANPDALRMDADAVAFVKAFFDAGKPVAAICHAPWTLIEA-------DVVRGRTLTSWPSLRT-------DVRN------------AGGEWVDEQ------VRVPSTLITSRKPL--------------------- +------------------------GVEQIELTRPWKDLEGAGATLELVSLESGQV----------QGHLDK--------ADTFRVD--RAINDADGDDYDALVLPGGVANPDDLRTNERAVAFVRDFMEKGKTVAAICHAPWTLVEA-------GVLKDRTLTSFPSVKT-------DIKN------------AGGHWVDEQ------VQVDKNLITSRKPL--------------------- +------------------------GFEEAELTEPVKALKEAGAQVEILSTKSGQI----------QAHHDK--------SITVNVD--RVLDRAEASEYDAVLLPGGALNADTLRMGPKVQSFLQQIQQAGKPFAVICHAAWELISA-------NLVQGRTLTSYYTIQD-------DIRN------------AGGNWIDKE------VVVDGNWVTSRQPI--------------------- +------------------------GFEETELTEPVKALKEAGAKVEILSNKSGEI----------QAHQDK--------GTTVNVD--RLIDQAQPSEYDAVLLPGGALNTDTLRMESKVQSFLKQMQQDNKPFAIICHAAWELVSA-------NLVQGRTLTSYYTIQD-------DIRN------------AGGNWVDRE------VVVDQNWVTSRQPI--------------------- +------------------------DFEDSEFTSPAEAFKLAGHQVITIEKQAGKT----------VKGKQG--------EAEVAID--RAIDDVTPGEFDALLLPGGY-SPDQLRGDERFVTFTRDFVNGGKPVFAICHGPQLLISA-------DVIRGRKLTAVKPIVV-------DVKN------------AGARVLRPG------GGG-------------------------------- +------------------------HFEDVEFTGPVEALKEAGHEVTVVGTEKGTV----------LVGKQE--------EAKVTVD--LTIDETSSSDFDALLIPGGF-SPDLLREDARFVTFTEEFDASKKPIFSICHGPQLMINA-------KIVKGRKMTGYKSNRP-------RKCR-------------GDV---------------------------------------------- +------------------------MFEDSEYSKPVNAFKKAGHKIIRVGLKEGEV----------VKGKKK--------GTPVKID--KAVTDVSVEDFDALLIPGGY-SPDKLRANEDAVKFTKEFAESGKPIFSICHGPQLLITA-------DVLKGRKITGWKSIIQ-------I----------------------------------------------------------------- +------------------------EFEDSEFTSPAAEFRQAGHEVITIEKEAGKT----------VKGKKG--------EASVTID--KAIDDVRPDEFDALLLPGGH-SPDYLRGDSRFVDFTRDFVNSGKPVFAICHGPQLLISA-------DVIRGRKLTAVKPIII-------DVKN------------AGAEFYDQE------VVVKDQLVTSRTP---------------------- +------------------------YMEDYEAMVPFQALQAYGIAVDAVCPGSGAY----------HGTEKP--------GHNFSLN--ATFDEVDFSKYDALVIPGGR-APEYLAMNESVLNCARQFSDSGKLIAAICHGPLILAAA-------GLLKAGSALH--TVLW-------DLFS------------S-----------------PVLFGLNPKP---------------------- +--TKNVLFIISEW-----------GYWGEELIGPLEACDAAGYNITFVTPNGKK---PTPLSPGYIDPPLEMGAKTVRVHESDRLDSPKSLADEELVNYDALVIVGGSGALIDLANNSRLHELILGFVKLNKPIAAECYGVTCLAFARDFREKKSLIWGKHVTGHPIDGTGFEGPHAI----------------------------------------------------------------- +--MKKILLVLSEW-----------GYWGEELIGPLEACDAAGYDITFLTPTGKK---PTPLSPGYIDPPLEMAEKTRQVNESNRLDRPKNLASEELGEYDALAIVGGSGAMIDLANNQRLHELILGFYKLNKPIAAECYGVACLAFARDFREKRSLIWGKHVTGHPIDGTGFEGFHGV----------------------------------------------------------------- +--MKKVIIVISEW-----------GYWGEELVGPVLSCDEVGYELTFVTPTGKK---PTPLSPGYIDPPLDMGRKTVELDRSGRLDNPKSLAENEISQYDALVIVGGSGALVDLANNQRLHDLVLGFVKLNKPIAAECYGVSCLAFARDFREKKSIIAGKHVTGHPIDGTGFEGPHAI----------------------------------------------------------------- +--TKNVIFVVSEW-----------GYWGEELIGPLEACDAAGYNITFVTPTGKK---PTPLTPGYFDPPLYYAQKTRELYESDRIDHPKSLADNELSGYDALVVVGGSGALVDLANNQRLHDLILGFYQLNKVIATECYGVTCLAFARDFREKRSIIWGRHVTGHPIDGTGFEGPHAI----------------------------------------------------------------- +--AKKVLIIATNY-----------GSWGEELQAPWDACKKAGFEVTLATPQGKK---PLPFQPDFVDGVQEVCDRCKELVDGEEWAHPLKFSEVNMADYDAIALTGGPGAMLDMCNCWELHKLIMDAYKSGKIVAALCYAVSTLVFLRDPENDKSIVYGKKICAHPRAPGMAMSYE------------------------------------------------------------------- +--------------------------------------------------------------PTFVDPIIEVCKRIKELTDGKEWASPITYKAAKMADYDAVVLTGGLGAMIDMCNNYNVHKLILDALEQNKLIGALCYAVSALVFCRDPKNDKSVIYGKTVVAHPHSRDWDFTYD------------------------------------------------------------------- +--SKKLLLVAPNY-----------GGWGEEQQAPWDIMRKAGFEVTMATPRGKK---PLPFAPDFVDPIQEVCRRVKEIVDGKEWEDAIKIDDAKMSDYDAIALTCGPGAILDVNGRKQLHDMLLEALYDKKIIGALCYSVAALVFARDPKNDKSIIWGKNVTAHPRSDL--DHSG------------------------------------------------------------------- +--SKKILIIASNL-----------GLWGEELQAPWDALKNAGHEVTLATMTGKT---PLPLVDTFIDPMQFVVDRIKKILETGQWNNPIKIEDAKMEDYDAIALVGGPGSPFDIVGNNDVHKLLLEAYKSNKIIGALCYVVGALVLTRDPDNEKSIIYGRKVTAHPAAP---LKYP------------------------------------------------------------------- +--MASILMVASNL-----------GVWAEELQGPWDVLNEKGHNVTLATEQGIK---PLPHVPDALDTVQSVVDRCKALWASTALDNPIAIKDAKMSDYEAIVLIGGPGAPLDMNGNSKLHKLLVDAFASDKLIATICYAVGGLVWARNPETGKSIIDGKVICAHPRDP---LPYP------------------------------------------------------------------- +--MKHILVVLSEY-----------GYWAEELVGPLREFDERGYRVTFATPTGKR---AHALPEEYIDPPLEVAELGRQVESGNRLDNPLSLTGTELEQFDALLIVGGSGPIVDLANNERLHDLILAFVRAGKPVGAECYGVACLAFARDWDDRRSIIWGKHVTGHCKEGTGFLGTD------------------------------------------------------------------- +--MRKILIILSEY-----------GYWGEELVGPLETFDAAGYQVDFATPTGKR---PVALPPTFVDPPLEMAEKVKRLEDNPRLDNPIILSEQDLAQYDALLIVGGSGPIVDLVNNHRVHDLILGFYKLGKPIAAECYGVTCLAFARDLVERKSMIRGKHVTGHCKEGTGFVGSD------------------------------------------------------------------- +--SKKILTVLSEY-----------GYWGEELLGPLECLEVAGHSLEFVTPRGGR---PRALPPGFVDPPLATAAKVRALDDSPRLDHPRNLAA-DLDDFAALLLVGGSGPIVDMVNNQRLHDVVLAFYQTNRPICAICYGVACLAFARDLNERQSILHGRHVTGHTVEGTGFLGSD------------------------------------------------------------------- +---------MSEY-----------GYWGEELVGPLEAFDARGYQVTFVTPTGKR---AHALPADYIDPPLEMARAVRALDESDRLDNPLSLADDLVAAYDALVLVGGSGPLVDMVNNERLHEVTLGFFAADKPILAECYGVTVLAFARDWESRQSIIYGKHVTGHPKEGTGFLGVD------------------------------------------------------------------- +--MKKLLFILSEY-----------GYWGEELIGPLETVEKAGYTVTFATSHGRR---PHALPDTFIDPPLEMAQKVKELEASSKLDNPINLSEEELKEYDAILLVGGSGPIVDMVNNQRVHDLILAFYRLGKPVVAECYGVACLAFAREYWTRKSIIWGKRVTGHPLEGTGFIGVD------------------------------------------------------------------- +--MQRVLIVLSEY-----------GYWGEELIGPKETLEKAGYILDYVTPTGKR---PHALPASYVDPPLEMAGKVKELEESDILDHPLSLKEEYCERYAALVLVGGSGPIVDMVNNVRVHDLIQIFYHADKAIAAECYGVACLAFARDYWLRKSLIWGKHVTGHPLEGTGFFGVN------------------------------------------------------------------- +--NMKILAVLSEY-----------GYWGEELVGPLLALDKQGYTVDFATQTGKR---AHALPAGYIDPPLEMELAVKQLEATTRLDNPLALNQQELSGYDVLLLLGGSGPVVDMVNNQRVHDLVLAFYKANKLIAAECYGVAVLAFARDCRDKQSIIWGKHVTGHPLEGTGFLGVD------------------------------------------------------------------- +--SKRILIVLSEY-----------GYWGEELVGPVEAFDSRGYRTTFATATGKR---AHALPPDYVDPPLDMARRARELDDSSRLDSPLSLAADLVDSFDALVIVGGSGPIVDMANNERLHELTLAFVAADKPILAECYGVAVLAFARSLENRTSLLWGRHVTGHPKEGTGFLGVD------------------------------------------------------------------- +--SKKILFILSEY-----------GYWGEELLGPLTACDEWGYHSVFATPTGKR---PHALPPGYVDPPLDVAVAARALDESPRLDQPVSLAEDDIAGYDALVIVGGSGPIVDLANNGRVHDLVLAFVRADKPIVAECYGVACLAFARDWDDRRGILRSKHVTGHPKEGTGFLGTD------------------------------------------------------------------- +--SRRILVIVSEH-----------GYWAEELIGPVSKFDERGYEVVFATPTGKR---AHALPANYVDPPLENARLGREFEQSSRLDSPLDIEAADIAAYDAILIVGGSGPIADLANNERVHALILAFRKAGKVVAAECYGVACLAFARDWDDRRSIIWGKHVTGHCKEGTGFLGTD------------------------------------------------------------------- +--SKKILYVLSEY-----------GYWGEELLGPVTATDAAGYESVFATPNGKR---PQALPPGYVDPPLEVAVAARELDESARLDDPLSLADTEVARYDALVIVGGSGPIVDLANNGRLHELILAFVRADKPVVGECYGVAPLAFARDWEDRTSIIRGKHVTGHCKEGTGFVGVD------------------------------------------------------------------- +--SKKILFILSEY-----------GYWGEELLGPLVACDRQGYTAVFATPTGKR---PVALPPGYVDPPLEVAVAARELDESSRLDNPVSLADQDVAEYDALVIVGGSGPIVDLANNGRLHELILAFIRADKPVVGECYGVAALAFAREWDDRKSIIWGKHVTGHCKEGTGFVGVE------------------------------------------------------------------- +--SKRILVVLSEY-----------GYWGEELVGPLEAFDARDYRTTFITPNGKR---AHALPSEYLDPPLDMARRARALDDSSRLDNPLSLAEELLSAFDALMIVGGSGPIVDLANNERLHELVLAFAAAGRPILAECYGVATLAFARDWESRRSLLWGKHVTGHPKEGTGFLGVD------------------------------------------------------------------- +--SKRVLVVLSEF-----------GYWGEELVGPLDVFDARGYRTAFITPTGKR---PQALPSEYIDPPLDMARRARAMDDSSRLDNPLSLAEELLASFDAMVVVGGSGPIVDLANNERLHELILAFVAAGKPILAECYGVAALAFARDAESRASLLRGKHVTGHPKEGTGFVGVE------------------------------------------------------------------- +--AGKVLIAVSEH-----------GFWVEELLKPLDHLKAAGIGFDFLVNKGDKV--PFPDGSTYSDPPLELAVRGKDMDWDSLFANRIALQEERIDEYDALLLVGGSGPVVDMVNNSRLHDLILGFYYKDKPIAAECYTVACLAFAREFDQRKCLLEGKHVTGHTMEGWAVMAGE------------------------------------------------------------------- +--AKRILVVLSEW-----------GYWGEELIGPLDVLTKAGYQLDFMTAFGRK---PPALPEGYLDPPLHFAKRTTEVHESNLLGNPINLSEEYVDPYDALLLPGGSGPMVDMVNNERLHNLILGYVDRDKLIAAECYCVTCLAFARDWTERKSIIWGKNVTGHAREGTGFAQMY------------------------------------------------------------------- +--MKKVLCIMSEW-----------GYWGEELVGPLDVLNEHGYQVDFVSPKGGR---PIALPETFMDPALHFAERTRQIEESDLFDGIRSLAEQ-LGQYSALLLPGGSGPMVDVVNNQRVHDVILGFLAQDKLIAAECYCVTTLAFARDWTDRTSIIRGKHVTGHALEGTGFAV--------------------------------------------------------------------- +--MKKILCMVSEW-----------GYWGEELVGPYDVLLEAGYQVDFMTANGRK---PPALPEGFLDTPLHYAKRTREVNDSDLLARPIDLADE-IEKYDALLLPGGSGPMVDMVNNERLHAVILGFLSQNKLIAAECYCVTCLAFARDWTDRKSIIWGKHVTGHAREGTGFARMY------------------------------------------------------------------- +--MKQILCVLSEW-----------GYWGEELVGPYDVLLKAGYSIDFATPKGRK---PPALPETYVDPPLHYAQRTKEVNGSDLLSQPINLAED-LEKYDALLLPGGSGPMVDMVNNERLHAVILGFLAQNKLIAAECYCVTCLAFARDWTDRKSIIWGKHVTGHAREGTGFAQMY------------------------------------------------------------------- +--SKKVLVILSEW-----------GYWGEELVGPYDVLNEAGYIIDFATPKGRK---PVALPETFIDPPLHYAKRTREIEQSDLLAKPIDLSNE-LEQYDALVMVGGSGPMVDMVNNERVHDVILGFLSQGKLITAECYAVTCLAFARDWTERKSIIWGKHVTGHARESTGFAQMY------------------------------------------------------------------- +--LKKILIILSEW-----------GYWGEELIGPLEMFDKAGYEVTFATPNGKR---PVALPPDYIDPPLEVAAKVKEIDQSPRLNYPLNIAEEYLTQYDALLIVGGSGPIVDLANNQRIHDIILSFYRMNKPIGAECYGVTCLAFARELENRKSLIWGKHVTGHCKEGTGFMGTD------------------------------------------------------------------- +--SRKILVIVSEH-----------GYWSEELIGPVSKFDEQGYEITFATPTGKR---AHALPPNFVDPPLENARLGREFEQSNRLDTPLDIEAADIAGYDAILIVGGSGPIVDLANNERVHALILAFKNAGKVVAAECYGVACLAFARDWGDRKSIIWGKHVTGHCKEGTGFLGTD------------------------------------------------------------------- +--NKKILAVLSNH-----------GYWGVELTGPALPLQRAGYEITYVTPTGDR---PIALPPDYWDPPLADAAEVKEFMGRAELDNPIDLSA-ELHQYDAILLVGGSGPIVDMVNNQRVHDLVLGFYRLGRPIAAICYGVAVLPMARDFNERRSIIAGKHVTGHCIEGTGFIGTD------------------------------------------------------------------- +--SKRILVVLSEY-----------GYWGEELVGPVEAFDKRAYQVTFMTPTGKR---AQALPPEYIDPPLDMARRAAELDASARLDNPLSLQDDLVSGFDALVIVGGSGPIVDLANNERLHEVVLAFTAADKPILAECYGVAVLAFARDLESRESLLWGKHVTGHPKEGTGFIGVE------------------------------------------------------------------- +--SKKILAVLSEY-----------GYWGIELVGPLEKLEEAGYTVEFITPNGKK---AEALPTTYVDPPLIAAEKVKAFEASNRLENRLNLSENVTEEYAALLLVGGSGPIIDMVNNQRVHDLTLAFYNKKMPVAGICYGVAPLVFARDFNERKSIINGKHVTGHCIEGTGFLHTD------------------------------------------------------------------- +--KKRILIVLSEY-----------GYWGEELIGPLETFDKAGYEITFATPTGKR---AVALPPEYIDPPLEMAEKVRAFDGSNRLDNPLDLSSQIADRYDALLIVGGSGPIVDLANNWRVHDLVLAFYNLGLPIAAECYGVACLAFAREQDDRASIIRNKHVTGHCIEGTGFMGTD------------------------------------------------------------------- +--SKRILVVLSEY-----------GYWGEELIGPLETFDKAGYQVTFATPTGKR---PVALPPDYVDPPLEMAAKVRAIDSSPRLDGPLDLSSQIADRYDALLIVGGSGPIVDLANNWRVHDLILAFHALDMPIAAECYGVAPLAFARDQEDRVSIIRGKHVTGHCIEGTGFMGTD------------------------------------------------------------------- +--MKKVLIILSEW-----------GYWGEELIGPLETFDNAGYQVDFATPTGKR---PVAISATYIDPPLDMADKVKAIDDNPRLDNPKNLRETDLQQYDTMLIVGGAGPMVDLVNNFRVHDLILCFYQMGKPIAAECYGVPALAFARDIGDRQSIIWGKHVTGHCLEGTGFMGENI------------------------------------------------------------------ +--MTKILIVLSEW-----------GYWGEELVGPLETFDAAGYQVDFATPNGKR---PVALGPTFVDPPLDMADKVRQLDDNPRLNNPKNLRERDLQTYDAILIVGGSGPMVDLADNQRVHDLILSFYQMGKPVAAECYGVACLAFARDIGDRKSIIWGKHVTGHCLEGTGFNGTNI------------------------------------------------------------------ +--TKKILIILSEW-----------GYWGEELIGPLETFDAAGYQVDFATPTGKR---PVALTATFVDPPLEMAEKVRAIDDNPRLNNPISLRDQDLSQYDSMLIVGGSGPLVDLVNNQRVHDLILNFYQMDKPIAAECYGVPCLAFARDINDRKSIIWGKHVTGHCLEGTGFMGTNV------------------------------------------------------------------ +--SKKILFILSEY-----------GYWGEELVGPLAACDEQGYQTVFATPTGKR---PVPLPPGYIDPPLEVAAAAAELDRSGRLDNPVSLAEEELRSFDAMVIVGGSGPIVDLANNGRVHELVLAFKRADKPLVAECYGVACLAFARDWEDRTSIIDGKHVTGHCKEGTGFVGVE------------------------------------------------------------------- +--SKKILVILSEW-----------GFWGEELVGPLEVLQSRNYKPVLCTPTGRR---PRALPPGYKDPPLEMAEKVRRLDDNPYLANQRSLKAALVEEFEALLLVGGSGPMIDLVNNYRVHDAILAFKQADKPIAAECYGVACLAKARNFDDPRSIIWGKHVTGHPQELAGVLDPETG----------------------------------------------------------------- +--SKSILIVLSEW-----------GFWGEELVGPLEQFDRAGYRSVFCTPTGRR---AHALPPEFEDPPLETAEKVKAVEDNPRLDNPRNLSAETADEFDALLIVGGSGPMIDLVNNYRVHDLILGFLEQDKPIAAECYGVACLAQARNFDDSRSIIWGKHVTGHAKENTGVLDPETG----------------------------------------------------------------- +----------------TLTDGTPTGFWAEEVAVPHSIFRDAGWNVTIATPGGR-APTMDQLSMGVAGGMPRAIARYLDS----TADQLRTPDRVDATTFDLVFYPGGHGPMEDLAYDATSGALLSRRLRSNAPLALLCHAPAAVLATEAGDAPS-PFAGRRMTGLSNREEG---LNRFAR-KAPWLLEDRLFELGVDYSKGVLPLRPYVVVDGNLYTGQNPQSSEKLARRLIAE--------- +-----------------------DRVEDVEFFYPYYRFVEEGYAVDVITPSGGAGYK-------------GM-----------GLKETIALDQVDPRDYDLLFIPGGLGELRRDPRAIAF---VQAVAGWGTTIGAVCHGPQVLV----D---AGLVAGRSMTSWHEVAPEI-------TA------------AG-------GTYLDALVEDGQFITSRKPGDM------------------- +-----------------------DGVEQVELVQPMEALRAAGAEVHLVSLACESAMNHD---------DKAD-----------TFPVDRSVDEVKIADYQGLVIPGGVDRLRADPAAVKL---VRDFVEHDKPVASICHGPWLLV----E---ANVVRGRTLTSWPSLQTDI-------RN------------AG-------GEWVDEVVVDQKLVTSRKPADL------------------- +-----------------------DGVEQVELTEPMKALQEAGAEVKIVALKSGKAWDFD---------HWGE-----------EFDVDLTIDHANPNDFQALLLPGGVDTLRMNEKAVQF---VRQMVRSGKPVASICHGPWMLV----E---ADVVEGRTLTSYPSLQTDI-------RN------------AG-------GKWVDEVVVDQGIVTSRNPNDL------------------- +MPSKKILIILSNAHTFLSPDAGPSGFFLQELAKPLQKLLDAGHEVTFASPKGQEPTSDP-NSESLLA--YAGNFNELQREQ-DLIERMRPFSTINDNELATVFIPGGHVPLQDLGANAELGRILRYLYQENKSTAAICHGPYALLSTKEAGDGSFVYDSYKITSWSDAEENVMKVESALRDAGAVMVEGAPEKIGGKPLAA------------------------------------------ +------------------------------------------------------------------------------------------------------------------------------------------------------ANGDSIVKGRKVTAFTNSEEEAVGLVEAV----PFLLETKLRELGAKFDG-VDNWQPHAVADGRLVTGQNPASSE------------------ +------------------------------------------------------------------------------------------------------------------------------------------------------ADGKSIFAGRKVTGFSNAEEEQVGKVKDV----PFLLEDKIKELGGQYEKAAELWAPKVLVDGNLYTGQNPNSAR------------------ +----SALFVVTGADHWTLADGTPTGYWAEELAEPHRIFREAGYEITIATPGGVPAPDQGSLSAAANGGAEPAAIGAYLDTIREGLDAPAKLEDVDPDVYDLVFYPGGHGPMEDLAVSEASGRILTRTLDSGKPLGVVCHAPAALLAA-RREDGSWPFAGYRMTSFTNAEEAAVGLAD----KAPWLVQDRLVELGADFVE-AAPFTPHTVTDRNLYTGQNPGSSAA----------------- +--------------------EHPTGLWLSELTHAWHVFDEHGLEQTLVSPSGGKVPLEPRAL-KF------PNYDKTAKAWRALLENTRSPDEIDSADYDAIYFTGGHAVMYDFPDSIGLQRITREIYERGT--------------------------------------------------------------------------------------------------------------- +----SVLVVLSDADHLDLKDGKPTGFYLNELMQPVKRLLDAGHQVTFATPGGLATLDKSSDDKKYFNNDDAAWR-----THRALLDTLKLTARAGYGEFDALYIPGGHAPMQDLLTSQAVGEALAAFHAAGKPTALVCHGPIA---------------------------------------------------------------------------------------------------- +----QVLVLLSSENQLALKDGQATGYYLNEFGVPADRLLKAGYELVLVTPRGNASVDQKSVDPQYFGGDAAEMQ-----RIQQVVAGL---DEVDLGQYEGLFIPGGHAPLIDLANNPQVGALLRHFHQAGKPTAAICHGPIA---------------------------------------------------------------------------------------------------- +----HVLVVLSDEAHLELKKGHKTGFYLNELMQPTKMLLDAGHTVTFATPKGKATLDESSNNAMYFNQDEKALK-----QYADLLHDLKLTSRIGVGQFDAIYIPGGHAPMQDLLKDKQLGKVLTAFHKAGKPTALVCHGPIA---------------------------------------------------------------------------------------------------- +----HVLVVLSDEGQLELKNKQKTGFYLNELMQPTKMLLDAGHTVTFATPKGKATLDESSNNAMYFNQDEKALK-----QYAGLLHDLKLTARIGIDQFDAIYIPGGHAPMQDLLKDKQLGKVLTAFHKAGKPTALVCHGPIA---------------------------------------------------------------------------------------------------- +------------------------GFEQSELTEPKRLLEAEGARVSVVSPAEATIK--GWKDKD----------------WGGVVAVDLPLDEADAGRFDALVLPGGVINPDTLRTDEAALGFIRSVAEAGKPVAAICHGPWLLINS-------GLADGRELTSWPSLQQ-------------------DLANAGAKWRN------AEVVVDGNVITSRKPDDIPAFSEAVVK---------- +------------------------GFEQSELIEPKRLLEAEGARVSVISPAEATIK--GWKEKD----------------WGEAVAVDIPLSEADAAGFDALVLPGGVINPDTLRTDQAAVDFIRDVAAAGKPVAAICHGPWLLINS-------DLANGREVTSWPSLQQ-------------------DLLNAGARWQD------TEVVVDGNLITSRKPDDIPAFSEAVVR---------- +------------------------GFEQSELTEPKRLLESWGAKVEVIAPGGAQIR--GWNHTD----------------WGDSVTVDRQLAQATAQSYDALVLPGGVLNPDTLRTDEQAIAFIRAFSTAQKPVAAICHGPWLLLES-------DLVRDRKVTSWPSVRT-------------------DLINAGARWQD------AEVVVDGQLITSRKPDDIPAFAAAVAK---------- +------------------------GFEQSELQEPKRLLESWGATVEVIAPGDAQIR--GWNHTD----------------WGDSVPVDTPLAQAKPDRYDALVLPGGVINPDNLRTNAQAIDFIRSVAASGKPVAAICHGPWLLVES-------GLVRDRKVTSWPSVKT-------------------DLSNAGGRWED------AEVVVDGQLITSRKPDDIPAFTDAVAK---------- +--------------------------------DDIPALEQAAATVHIISPKGGKVK--GWKHTE----------------WGDTFTVDATLADAQPDDYDALLLPGGVMNPDTLRTIPEAVSFATRFFDDGKPIASICHGPWLLAET-------GKISGYTLTSYPSIRT-------------------DLKNAGANVVD------REAVVDRGVVTSRNPDDLPAFNKAMIE---------- +------------------------GFEQSELEKPLQALREAGAQVDVVSPGATSIK--GWDQKD----------------WGRSVDVDVPLSKADAGRYDALVLPGGQMNPDTLRKDADAVAFVRTFGQSGKPVAAICHGPWLLVES-------GLAKGRKVTSWASIKT-------------------DLVNAGADWQD------AEVVVDGNLITSRKPDDIPAFNDAIAT---------- +------------------------GFEQSELQEPKRLLEGWGATVTVIAPGASQIR--GWKGKD----------------WGESVAVDQALTAAKPDAYHALVLPGGVINPDTLRIDTQAVDFIKAFGASGKPVAAICHGPWLLVES-------GLAKGRAVTSWPSLKT-------------------DLTNAGAQWRD------AEVVVDGNLITSRKPDDIPAFSDAVAK---------- +------------------------GFEQSELQEPKRLLESWGATVEVIAPGDAQIR--GWNHTD----------------WGDSLPVDMPLAQAKPDRYDALVLPGGVINPDNLRTNTQAIDFIRSVAANGKPVAAICHGPWLLVEA-------ELVRDRRVTSWPSVKT-------------------DLSNAGGRWED------AEVVVDGQLITSRKPDDIPAFTDAVAK---------- +------------------------GFEQSELIEPKRLLESWGAKVDVIAPGAAQIR--AWNKTD----------------WGDSVPVDQRLDQAKVDSYDALVLPGGVLNPDTLRGDAKAIAFIQAFASADKPVAAICHGPWLLVES-------ELVRDRDVTSWSSVKT-------------------DLRNAGARWQD------AEVVVDGSLITSRKPDDIPAFTAAVAK---------- +------------------------GFEQSELTEPKRLLEAEGARVSVVSPAEATIK--GWKEKN----------------WGDAVAVDIPLDEADPARFDAVVLPGGVINPDTLRTDDAVLAFIRAVDEAGKPVAAICHGPWLLINS-------GLAEGRDVTSWPSLQQ-------------------DLVNAGAKWRD------TAVVIDDNLITSRKPDDIPAFSEAVVK---------- +------------------------GFEQSELTDPKKLLEGWGATTRVVSPAEGSIK--GWKEKD----------------WGDEVTVDQPLADANPDDFDALLLPGGQMNPDTLRIDASALAFIEAFGKAGKPVAAICHGPWLLIDT-------GLAKGRQVTSWPSVRR-------------------DLENAGAQWRD------EEAVVDGTLITSRKPDDIPAFSEALAK---------- +------------------------GFEEAELVEPQRALTAEGAQVEVISRQPGEIQ--GFRHVD----------------KGRRVKVDRTFDDVREGDYDAIVLPGGVVNGDAMRMIPAAREFVTAAAGANKPIAVICHGGWLLVSS-------GLVDGRTMTSWPSLQD-------------------DIRNAGGKWVD------QQVVRDGNLISSRKPDDLVAFNGALVD---------- +------------------------GFEQVELTEPQRALQAEGAKVEVISQKAGEIQ--GFKHVD----------------KGDPTRVDRLFDEARADDYDAVVLPGGVVNGDAIRMIPAARRFVSEAHAADKPIAVICHGGWLPVSA-------GIVKGHRMTSWPSLQD-------------------DIRNAGGEWVD------ERVVRDGNLITSRKPDDLDAFVSTLVE---------- +------------------------GFEQAELVEPQRALKAAGAQVHVISQKPGQIQ--GFKHVD----------------KGDKVDVDVTLDSANAADYDALVLPGGVVNGDAIRLDAKAQSFVKEADQAKKPIAVICHGGWLPISA-------GIVAGRTLTSWPSLQD-------------------DVRNACGTWVD------QEVQIDGNLITSRKPDDLPAFNQALID---------- +------------------------GVEEAELVEPLNALKKAGIEVTVASNSGESIQ--TVTGKD----------------WASKVNADSRLADAKASDYDLLVIPGGTVNADTLRIDEDGRRLVKEFATAGKPVGAICHGPWVLIDA-------DVAKGKTMTSYISIRP-------------------DLENAGASWVD------KELFRCPVLLTSRNPNDLPAFAKALVD---------- +------------------------GVEEPEIISPRDALSSAGIDVTIASNSGNDIQ--TVTGKD----------------WASTVKADTTLDKISADDYDLVVLPGGTVNADTLRIDTEAQRILNEFASAHKPVGAICHAPWALIDA-------GLTEGKTMTSYQSIRT-------------------DLKNAGAHWVD------EEVFRCPVLITSRNPHDLPAFTKALTD---------- +------------------------GVEEVELTEAVAALRQAGAQTVLVSPTHGSIQ--AMEAVH----------------PTHRYQVDLLVAQAHARNFDGLVLPGGTTSPDHLRMDDDAVRFVREFVQADKPIAAICHGPWTLINA-------NGLRGHRITSWPSLRA-------------------DLTNAGAHWVD------EEVVTDGTLVTSRNPHDLKAFCPAIVA---------- +------------------------GVEEVELTEPVAALQQAGARTVLVSPTHGYIQ--AMKAVN----------------PTHRYQVDMLVGQAHARNFDGLLLPGGTTSPDHLRMDEDAVRFVREFVQADKPIAAICHGPWTLINA-------NGVRGHRMTSWPSLRA-------------------DLTNAGAHWVD------EEVVSDGTLVTSRNPHDLKAFCPAIVA---------- +------------------------GVEQDELVVPVKHLRDHGAQVSVAAVSADGIR--TLVGRD----------------PGETVRPDLTLDDVDPAAYDLLLVPGGTLNADSLRLEDATTRIVSSFAASGRPVAAICHGPWALVEG-------GYVQGKTLTSYASLRT-------------------DITNAGGTWVD------KPVVRDDPLITSRNPGDLDDFLGEIDA---------- +------------------------GVEQDELLVPLEHLRGAGVRVDVAAVSMDDIA--TLVGKD----------------PGKTVRPDLTLADADPAAYDVLLVPGGTLNADTLRLQNATTDIIRSFTDSGRPVAAICHGPWALVEA-------GVVAGKRLTSYASLRT-------------------DIRNAGGEWTD------EPVVTDGTLITSRNPGDLDAFLGEIDA---------- +------------------------GVEQDELLVPLEHLRGAGARVDVAAVSMDDIL--TLVGKD----------------PGKTVRPDLTLDDADPADYDLLLIPGGTLNADTLRLQNATNGIIRSFTDSGRPVAAICHGPWALVEA-------GVVPDKRLTSYPSLRT-------------------DIRNAGGEWTD------EPVVTDGTLITSRNPGDLEPFVREIRT---------- +------------------------GVEQDELVVPVRHLRDAGATVDIAAVSDEPIR--TLVGKD----------------PGETVRPSLTLSEVDPAGYELLLVPGGTLNADTLRLQDATPAIVRSFTTTGRPVAAICHGLWALVES-------DAVREKTLTSYASLRT-------------------DIRNAGGTWVD------EPVVRDDTLITSRTPDDLDAFLGEVRK---------- +------------------------GVEQDELVVPVRHLRDAGATVDVAAVTADAVR--TLVGKD----------------PGETVRPSMALSDADPSGYDLLLVPGGTLNADTLRLQNDALDILRSFTSSGRPVAAICHGPWLLVEA-------GSLTGKTLTSYASLQT-------------------DIRNAGGTWVD------KPVVTDDRLITSRDPGDLDDFLREIDA---------- +------------------------GVEQDELVVPVEHLRGAGARVDVAAVTTDDIV--TLVGKD----------------PGRTVRPDLTLADADPADYDLLLIPGGTLNADTLRLQSSAGTIVRSFTDSGRPVAAICHGPWALVEA-------GVVAGKRLTSYASLRT-------------------DIRNAGGTWAD------EPVVTDTLLITSRNPGDLDPFIREMDT---------- +------------------------GVEQDELVVPLEHLRSAGVDVDVAAVTSDPVE--TLVGKD----------------PGTTVPPTLRLQDVDPGGYDLLLVPGGTLNADSLRLEGTAVEAVRSFATSGRPVAAICHGPWVLVEA-------GVLAGKTLTSYPSLQT-------------------DVRNAGGSWED------RSVVRDDALVTSRNPGDLPDFLREVDA---------- +------------------------GFEQVELTGPKEALEQAGATVEILSTEEGQVK--GWNHDK----------------PADDFKIDRTFKAANASDYHGVVLPGGVQNSDTIRIDTDAQKLVKDIEGSGKPVAVICHGGWLLISA-------GLVKGKTLTSFKTLKD-------------------DLVNAGAKWVD------QEVVTDGTLISSRQPDDIPAFNSKLIE---------- +--PRKVLMVVTAARVWTLKTEHPTGFWGEELAVPHELFTKAGWEITIATPGGVAPLDALSMGVSGGLPSQRRRVRAYLDSIAGALARPVPLEDIDSTDYDLVFYPGGHGPMEDLAFDATSGALLRQRIEAGAPLALLCHAPAAILAAP------DAFSGRRMTGLSNKEELLNPFAW----KAPWLLEDEMKKARVEYHAG-FPLRPHMVVDQNLYSGQNPQSSRDLALRII----------- +-----------------------DGFEQIELTAPVKKLERQGADVTIVSPYRGRIR---GMNHLM-----------PG----KKVSVDATLREVKAADFDAVLIPGGLVNPDLLRQSALALDFVRDADALDLPIAVICHGPWVLISA-------GLVEGRSLASWPGIRD-------------------DVRNAGGRWVD------QAALRDGNWVSSPGPRQMFAFIKGMVELFE------- +-----------------------DGFEQVELTIPVKALRKRGAQVDIISLHKGHIR---GMNLMW-----------PG----KKVRVDETVDKVRPTDFDALLIPGGFVNPDKLRQSEEVLDFVREFDRHGRPIATLCHGPWVLVSA-------GLASGRKLASWPGIKD-------------------DLRNAGAQWMD------EPGVRDDRWFSSRSPLDMRHFIKGMVSLFD------- +-----------------------DGFEQVELTIPVKALRKRGAQVDIVSLRKGKIR---GINLMW-----------PG----KKVPVDETVDTVRPRDFDALLIPGGFQNPDSLRQSEEVLDFVREIDRLGRPIATLCHGPWVLVSA-------GLANGRRLSSWPGIKD-------------------DIRNAGAEWRD------ESGVLDGRWFTSRGPQDMRHFIKGMVSLFA------- +-----------------------DGFEQVELTRPVKRLEREGAHVTIVSLHKGRIR---GMNLLV-----------PG----RKVRVDATLRDVKAADFDALLLPGGFMNPDFLRQSALALDFVKDADLLDQPIAVICHGPWLLASA-------GLLEGRHLTSWPGIRN-------------------DMENAGAHWTD------EPVVRDGNWVSSRGPHDLLAFEHAMVELFA------- +-----------------------DGFEQVELTHPVKKLKREGALVEIISLRPGSIR---GMNLLY-----------PG----KKVHVDTTLREVKAADYDALLLPGGFVNPDLLRQSELALEFVRDFERLDRPIAVICHGPWLLASA-------DVVRGRRITSWPGIRD-------------------DLHNAGGIWED------APVVRDGTWVSSRGPHDLLEFIPAMVSLFA------- +-----------------------DGFEQVELTAPVKKLERQGADVTIVSPHKGRIR---GMNLLI-----------PG----KRVSVDASLREVKAADFDAVLLPGGFVNPDLLRQSALALDFVRDADALDMPIAVICHGPWVLISA-------GLVEGRALAAWPGIRD-------------------DVRNAGGRWVD------EPVMRDGNWVSSPGPRQMFAFIKGMVELFA------- +-----------------------SGFEQVELTRPVKKLQRQGAEVTVVSLLPGHIR---GMNHML-----------PG----KKVRVDATLRDVKAADFDAVLLPGGLINPDTLRQSALAKDFVHDADSLNLPMAIICHAPWLLISA-------GLTEGRTLTSWPGIQD-------------------DVKNSGAMWRD------DEMVRDDNWVSSRGPQDLPAFERAMVELFA------- +-----------------------DGFEQVELTQPVQKLRQEGACVKIISLLPHSIR---GMNHLV-----------PG----KKVAVDAPLKKVKAADFDALVLPGGLANPDTLRQSELAREFVTDFERLGRPVAVICHGPWLLISA-------GLVRGRRLTSWPGIQD-------------------DVRNAGGLWED------AAVVRDGTWVSSRGPQDLPAFDQAMTALFA------- +-----------------------DGFEQVELTRPVRTLERHGADVKIVSLQPGYIR---AMKHMV-----------PG----KRVRVDATLKDVKAADFDAVLLPGGLINPDTLRQSALARDFVHDADSLNLPMAIICHAPWLLISA-------GLAEGRTLTSWPGIRD-------------------DVKNAGANWRD------EPLVHDDNWVSSRSPHDLPHFEKALVELFA------- +-----------------------DGVEQIELTSPVKHLEKHGAQIEVISLHPGKIK---GMNLLL-----------PG----KNIKVNRTIFRANPDNYDALLIPGGHINPDFLRQSDSVLQFVREFDAANKPIAVICHGPWVLVSA-------GVVKNRTLTSWPGIKD-------------------DVINAGGNWVN------NAAVRDGNWISSRSPLDLIQFNREMISLFA------- +-----------------------DGFEQVELTSPKAALEEAGATTKILAPHSGVVQ---GVNHDV-----------KA----DEFRVDMVLGQADPDDFDAVLLPGGALNADALRVVPEAQKFIRAIDAKNKPVAVICHGPWLLVSA-------GLVQGKTMTSYHTIRD-------------------DIRNAGANWVD------NELVRDENWVSSRSPKDLPAFNKGMIGLFS------- +-----------------------HLYQELELWHPVLRLREAGANVLLVGPDTRLVY---SSKLGY-----------P-------ARPDLSIDDVKAEDFDAVVIPGGFA-PEGMRRHPAMIEFVREMDAQGRLIAAICHAGLVLASA-------QIARNRKLTCVSLVKD-------------------DVINAGANYVN------EGLVIDHNIITSQLPSDLPVFGKAIVDYLS------- +-----------------------HHYQELELWYPLMRLREAGCNVLVVAPSDTQIY---GSKLGY-----------P-------IVADLAAEQADAADFDAVIIPGGFA-PEGLRRNPAIVNLVKGVHDRGGLVAAICHAGWVLATA-------GIARGRDLTCVSLIKD-------------------DVINAGANYID------QPVVQDGNLITSRLPGDLPEFGRAIVDYLA------- +-----------------------SAFEDSEFLIPYNALQQAGADVKILGSRGHVS---------YAG--------KQ---GRISINADASTAEVLARSFDAICIPGGMA-PDTMRTNMRTVHLVRDALHQGKLVAAICHGPQVLIEG-------DLLRGKNATGFRAIRK-------------------DIQNAGATYID------VPLVEDGNLLTARRPGDLPIFATALL----------- +-----------------------SGFEDSEFQVPYTALQKAGANIVIVGSRMNDE---------YEG--------KQ---GKVSAKPDATAAEVRSEDFDAIFIPGGAA-PDKVRRNPHAVTLVIDGMAQGLPIAAICHGPQVLIDA-------DVLRGKQATGFKAIRK-------------------DIQNAGATYVN------EPVVVDSNLITARQPSDLPMFTVTLL----------- +-----------------------NQFEGSAYQVPSTALRKAGGTVSVIGSRMNEG---------YQD--------KQ---GSVTVKPIATSTEVRAGDFDAIVIPGGH-----IRANPNMVRLVSQSIDQGIWVAAVGYGPQILIEA-------DRLRDKHTTSARSIHK-------------------DLLNAGAIYVN------EPVVVDGNLITARQPSDLPMFTTMLL----------- +-----------------------NKFEDLEFQIPHTALQKAGATVTVLGSRMNEE---------YQS--------YR---GTVLIKPDATATEVSADNFDALVIPGGS-----IRTNPNVVRLVTNAINQDKWIAAVGHGPQVLIEV-------DQLKNKQVTGCRAIRK-------------------DIENAGAIYLD------KPTIVHDHLITARRPGDLPIFTTTLL----------- +-----------------------NHFEDSEFQIPYTALKQANAEVVVLGSRMNDT---------YKG--------KR---GKVSIKPDATATEVRSEDFDVIIIPGGAA-PDAIRANPNAVRLVMNGMAQNKLIAAICHGPQVLIEA-------DQLRGKRATGFQAIRK-------------------DMQNAGAIYID------EPVIVQENLITARRPGDLPMFTTIIL----------- +-----------------------NHFEDFEFKIPYTALKQAGSEVVVIGSRMNDE---------YQG--------KR---GKESVKPDATATEIRAEDFDCIIIPGGNA-PDRIRANPNAIRLIIDAMAQEKLIATVCHGIQVLIEA-------DQIRDKQVTGFRSIRK-------------------DIENAGATYID------EPVVVQGNLITARQPGDLPIFTTVIL----------- +-----------------------QGFEDSEFQIPYLALRETGARVTVVGSRMNSE---------YHG--------KQ---GKVTVKPEATATEVRSEDFDLIVIPGGHA-PDVMRTNPNMVRLIMDAMGQEKLIAAVCHGPQLLIEA-------DQLRGRRATGFRAIRK-------------------DMQNAGATYID------EAVVVDGNLITSRQPGDLPMFTTVIL----------- +-----------------------SGFEDSEFQVPYTALRNAGANTVIIGSRMNDE---------YQG--------KQ---GNVSAKPDATAAEVRSEDFDAIFIPGGAA-PDKIRSNPQAVRLVIDAMAQGLPIAAICHGPQVLIDA-------DVLDGKQATGYKAIRK-------------------DIHNAGATYVN------EPVVVDGNLITARQPSDLPMFTVTLL----------- +-----------------------NEFEDVNFKIPNTALKQAGAIVTVLGARMNDD---------YKG--------HH---GTLTVTPDATPAEVNAEDFDAFILLGGS-----NRVNPNVVTLIQNAIALNKWIVAIGFGPQILIET-------GQLTGKQVTGFRAIRT-------------------DLENAGATYID------TPTAVDSPIITARRPGDLPILMTTLF----------- +-----------------------NQFEDLEFKVPYTALQKAGATVTVLGARMNDE---------YQS--------YR---GTVSIKPDATATEVVAEDFDAFVIPGGS-----IRTNPNVVRLVTNANLQGKWIAAIGYGPQVLIEA-------DLLKNKSATGCRAIRK-------------------DIENAGATYLD------APAAVDEHLLTARRPGDLPIFTTTLL----------- +-----------------------NGVEDIEFTIPCHSLKQAGMEVVVLGSRMNER---------YKG--------KR---GKLSVQPDATTTEAIAGKFDAVVIPGGMA-PDKMRRNPNTVRFVQEAMQQGKWVAAVCHGPQLLIEG-------DLLKGRKATGFSAIRK-------------------DMINAGANYLD------EPLVVDRNLITSREPGDLAIFTTALL----------- +-----------------------NAVEDVEFLIPYNALKQAGIEVVVLGARLNEK---------YKG--------KQ---GKLSMQADRTITDAIASEFDAVVIPGGMA-PDKMRRHPNTVRFVQEAMQQGKWIAAVCHGPQVLIEG-------DLLKAKQATGFSAIRK-------------------DMINAGANYLD------EPLVIDGNLITSREPGDLAIFTTAIL----------- +-----------------------NGVEDIEFAMPCNGLKQAGMEVVVLGSRMNER---------YKG--------KR---GKLAVQPDATTTETTVDNFDAVVIPGGLA-PDKMRRNPNTVRFVQEAMQQGKWVAAICHGPQLLIEG-------DLLKGRKATGFNAIRK-------------------DISNAGANYLD------EPLVVDGNLITSREPGDLPIFTTALL----------- +-----------------------NGVEDAEFQVPYNGLKQAGMEVVVLGARMNEK---------YKG--------KQ---GKVSQQADGTTTEAIASEFDAVVIPGGMA-PDHMRRNPNTVRFVQQAMQQGKLIAAVCHGPQVLIEG-------DLLKGKQATGFSAIRK-------------------DMINAGAKYVD------EPLVVDGNLITSRQPGDLAIFTTAIL----------- +-----------------------QAVEDVEFIIPCNGLKQAGFEVVVLGSRMNEK---------YKG--------KR---GKLSIQADATTTEAIASEFDAVIIPGGMA-PDRMRRNPNTVRFVQEAMQQGKLVAAVCHGPQVLIEG-------DLLKGKRVTGFSAISK-------------------DMMNAGANYLD------HPLVVDGNLITSREPGDLAIFTTAIL----------- +-----------------------EGFEDSEFKVPYTAFQQAGAKVSVLGSGMNQT---------YQG--------QQ---GKVSIQPDGTTTEARAQNFDAVIIPGGSA-PDKMRTNPNTIAFVKEAAALGKLIAAVCHGPQVLIEA-------DLLRGRRATGFISIRK-------------------DMENAGATYID------EAVTTDGTLICSRQPGDLAIFTTAIL----------- +-----------------------QAVEDAEFIIPCNGLKQAGFEVVVLGSRTNEK---------YKG--------KR---GRLSTQADGTTTEAIASEFDAVVIPGGMA-PDKMRRNPNTVRFVQEAMQQGKLVAAVCHGPQVLIES-------DLLRGKQATGFIAISR-------------------DMINAGADYVD------EALVVDGNLITSREPGDLAIFTTAIL----------- +-----------------------NGVEDAEFTVPYNGLKQAGMEVVVLGGRMNEK---------YKG--------KQ---GKVSIQADATTTEAIASEFDAVVIPGGMA-PDKMRRNPNTVRFVQEAVQQGKWVAAVCHGPQLLIEG-------DLLQGKRITGFRAIRK-------------------DIINAGADFKD------EALVVDGNLITSREPGDLAIFTTAIL----------- +-----------------------QAVEDAEFTVPYNGLKQAGIEVVVLGSRMNEK---------YKG--------KR---GKLSIQADGTTTEAIAAQFDAVIIPGGMA-PDRMRRNINTVRFVQEAIQQGKLVAAVCHGPQVLIEG-------NLLKGKQATGFIAIAK-------------------DMINAGAKYLD------EPVVVDGNLITSREPGDLPIFTTAIL----------- +-----------------------NDVEDAEFTIPCNGLKQAGMDVVVLGSRMNEK---------YKG--------KR---GRVSVQPDGTTTEAIASEFDAVVIPGGMA-PDKMRRNPNTVRFVQEAMQQGKLVAAVCHGPQLLIEG-------DLLRDRRATGFVAIRR-------------------DMINAGANYQD------EALVVDGNLITSREPGDLAIFTTAIL----------- +-----------------------NGVEDVEFQIPYNALKQAGFDVTILGSRTNET---------YKG--------KQ---GKLAKEADGTTTEAMASEFDAVIVPGGMA-PDRMRRNPNTVRFVQEAMEQGKIVAAVCHGPQVLIEG-------DLLKGKTATGFIAVRK-------------------DMINAGANYVD------EPLVVDGNLITSRQPGDLPIFTTAIL----------- +-----------------------NGVEDAEFQVPYKGIKMAGMDVTVLGSRMNET---------YKG--------KQ---GKVSVQPDGTTTEAMAADFDAVVIPGGMA-PDKMRINPNTVQFVKEAMQQGKLVAAVCHGPQVLIEG-------DLLKGKQATGFVAIKQ-------------------DMINAGANYSD------EPLVIDGNLITSRQPGDLAIFTTAIL----------- +-----------------------NFVEDAEFQVPYNALKQAGMEVVVLGSRVNET---------YKG--------KQ---GKLSKQADSTTTEAIASEFDAVVIPGGMA-PDYMRRNPNTVRFVQEAMQQGKWVGAVCHGPQVLIEG-------DLLKGKQATGFIAIRK-------------------DMINAGANYID------EPLVVDGNLITSRQPGDLAIFTTAIL----------- +-----------------------NDVEDAEFQVPFNALKQAGMEVVVLGSRVNET---------YKG--------KQ---GKLSKQPDGTTTEAIASEFDAVVIPGGMA-PDHMRRNPNTVRFVQEALQQGKLVAAICHGPQVLIEA-------DLLKGKQATGFLAIRK-------------------DIINAGANYVD------EPLVIDGNLMTSRQPGDLPIFTTAIL----------- +-----------------------NDVEDAEFQVPYNALKQAGMEVVVLGSRMNEK---------YHG--------KR---GKVSMQPDGTTTEAMASAFDAVIVPGGMA-PDKMRRNPNTVGFVQDAMQQGKLVAAVCHGPQVLIEG-------DLLRGKQATGFIAIRK-------------------DMINAGANYID------EPLVIDGNLITSRQPGDLAIFTTAIL----------- +-----------------------QKFEDAEFKIPYQALQQAGAQVVVLGSRMNDT---------YQG--------KQ---GKVSIKPDGTVTETRPDTFDAVIIPGGMA-PDTMRNNPNAVQFVQKAMELNKLVAAVCHGPQVLIEG-------DLLQGKNATGFLSIRK-------------------DMTNAGANYVD------EPLVVDGNLITSRQPGDLAIFTTAIL----------- +-----------------------NGVEDAEFKIPYEALKMAGIETVVLGSRTNET---------YKG--------KQ---GKVSQSADGTTTEAVASEFDAVIIPGGMA-PDKMRVNPNTVRFVQEAMQQGKLVAAVCHGPQVLIEG-------DLLRGKQATGFIAVRK-------------------DMINAGANYVD------EPLVIDGNLITSRQPGDLAIFTTAIL----------- +-----------------------QNFEDCEFQIPYKALQQAGAQVVVLGSRMNEK---------YEG--------KQ---GQVSIKPDGTVTEARPEDFDAVVIPGGMA-PDTMRNNPNAVKFIQKAMELRKLVAAVCHGPQMLIEG-------DLLKGKNATGFVSIRK-------------------DMINAGANYLD------EPLVVDGNLITSRQPGDLAIFTTAIL----------- +-----------------------KMVEDSEFQIPYQALKQAGMEVVILGSRMNEQ---------YPG--------KQ---GKVSIKPDATTTEARPEYFDAVIIPGGAA-PDMMRTNPNTVRFVKEAMTQGKLIAAVCHGPQVLIEA-------DLLRGKNATGFDSIRK-------------------DMENAGAKYYD------EPIVVDGNLITSRRPGDLAIFTTAIL----------- +-----------------------QNVEDAEFQIPYNALKQAGAQVVVLGSRVNEE---------YKG--------KQ---GKLSIKADATTTESFASDFDAVVIPGGMA-PDRMRTNMKTVRFVQDAFGLGILVAAICHGPQVLIEG-------DLLSGIRATGFRSIRK-------------------DMQNAGANFVD------APLVVEDNLITSRRPGDLPIFTTAIL----------- +-----------------------NGVEDSEFLVPYNALKQAGFEVVVLGSRTNEK---------YAG--------KQ---GKVAQQADGTTTEAVPAEFDAVIIPGGMA-PDMMRTNPNTVRFVREAFEQGKIVAAVCHGPQVLIEA-------DLLKGKNATGFLAIKT-------------------DMINAGANYIN------EALVVDGNLITSRQPGDLAIFTTAIM----------- +-----------------------QGVEDAEFQLPYNALKKAGAEVIVLGSRVNEE---------YKG--------KQ---GKLNIKADATTTESIATDFDAVIIPGGHA-PDKMRTNMKTVQFVEDALENGVLVASVCHGPQVLIEG-------DMLDGVRATGFRAIRK-------------------DMQNAGAEFVD------EPLVIDDNLITSRRPGDLPIFVTAIL----------- +-----------------------NYVEDSEFQVPYNALKQAGMEVVVLGARMNES---------YKG--------KQ---GKLSKQPDGTTAEAIASEFDAVVIPGGMA-PDKMRRNPNTVRFVQEAVQQGKIVAAVCHGPQVLIEG-------DLLRGKQATGFLAISR-------------------DMINAGAKYVD------DPLVVDGNLITSRQPGDLAIFTTAVL----------- +-----------------------NGVEDSEFQVPYNGLKQAGFEVVVLGSRMNEK---------YAG--------KQ---GKVAMQADGTTTETRAEDFDAVIIPGGMA-PDIMRTNPNTVRFVTEAMEQGKLVAAVCHGPQVLIEG-------DLLKGKKATGFHAIRK-------------------DMINAGAEYIN------EALVIDGNLITSRQPGDLAIFTTAIL----------- +-----------------------QEVEDVEFTVPYNGLKQAGMEVVVIGSRMNEK---------YKG--------KR---GKLSVQAEATTAEAVAEEFAAVVIPGGMA-PDKMRRNCNTVCFVRDAMNQGKLVAAICHGSQVLIEG-------DLLKGKQATGFTAIRK-------------------DISNAGATYLD------EPLVMDGNLITSREPGDLAIFTTAIL----------- +-----------------------HGVEDVEFTVPYNGLRQAGMEIVVLGSRMNEK---------YKG--------KR---GKLTVQPDGTTTEAIASEFDAVIIPGGLA-PDKMRLNLNTVRFVQEAVQQGKLVAAVCHGPQVLIEG-------DLLKGKQVTGFSAIRK-------------------DLINAGANYLD------EPVVVDGNLITSREPGDLAIFTTAIL----------- +-----------------------QGVEDVEFIVPFNGLKQAGIEVIVLGSRMNEK---------YKG--------KR---GKLSIQADATTTEVVADEFAAVVIPGGMA-PDKMRRNCNTVWFVMEAMKQGKLIAAVCHGPQVLIEG-------DLLKGKQVTGFAAICK-------------------DITNAGANYLD------EPVVVDGNLITSREPGDLAIFTTVLL----------- +----------------------------------------------------------KTAIHDFE--GDQTYTEKPGHNF----VLNYSFDDVKVSDYDGLVIAGGRA-PEYLRLNGELIEMVKHFFEADKPVAAICHGIQILTTA-------GVVKGRKLTAYPAVGP-------------------EVTLAGGEFQDIP---ADAAFVDGNLVTSPAWPGHPSF---------------- +---------------------------------------------------------------------------MRGHSF----TITKTFDEEDVTEYQGLYITGGRT-PEYIRLNQKVLELTRHFCDNNLPIAAICHGIQVLFAA-------GVTESRTLTCYLAVLP-------------------DMIIAGGKYKEVL---PTEMVKDGNLIMSPARPDHQGL---------------- +-----------------------------------------------------------------E--GDQTYTEKRGHNF----ALNATFANINAADYDALYLPGGRA-PEYLRLNAKVIEIIQHFATADKPIASICHGPQLLTAA-------GVITGKKVSAYPACQP-------------------EVKMAGAEYVELP---MDGAITDGKLVTAPAWPAHPAM---------------- +---------------------------------------------------------------MID--GAQTYSDKPGHRF----TLNADFAAVKAENYDALVIPGGRA-PEYLRLNEEVIKLVQAFDAARKPIAAVCHGPQLLAAA-------GILQGRTCSAYPACAP-------------------EVRLSGGHYADIG---IDQAHVDGNLVTAPAWPAHPQW---------------- +--------------------------------------------------------------------------------------MNATFDKVKVADYDALVILGGRA-PEYIQLNERVLEMVRHFAERKKPIASICDGMQVLTAD-------GVIEGKTCTAYPALAP-------------------EVKRAGGKWLDVP---LDKAYVDGNLVTSPAWPAHPEW---------------- +-------------------------------------------------------------IHDFE--GDQTYSEKRGHNF----ALNATFADIKVADYDALVIPGGRA-PEYLRLNADVLSAVKHFFEADKPVAAVCHGAQLLAAA-------GVLKGRTCSAYPACRP-------------------EVELAGGTYADIA---IDAAVTDGKLVTAPAWPAHPAW---------------- +----------------------------------------------------------QLVVHDFT--TLNTYIELPGHRI----PVDVSMSDVKAKDYAGLVVPGGRA-PEYIRLYDETIKLVQDFFAAGKPVAVICHGLQLLAAA-------KVLEGYKVTSYPACAP-------------------ECRLAGADWQSE------SVIIDKNLVTAQAWPNYPAW---------------- +----------------------------------------------------------KTAIHDFE--GDQTYTEKPGHLF----RLTASFDDIRLQEYSGVYISGGRS-SEYLRLNKSVLDIVHYAMNLTLPVAAICHGPQILAAA-------GVLKGRKLTGYFTVKP-------------------EVEMAGGQWVTAA---DDEAIVDGNLITATTWMGHPAI---------------- +----------------------------------------------------------KTAIHDFE--GYQTYTEKIGHNF----QLNASFNYLKLEDYDGLYITGGRA-PEYLRLNNKVIDIVKFFIDLNKPVAAICHGIQILTAA-------NVIKGRKLTAYSAVKS-------------------EVILAGGLFQDIK---PDESIVDGNLVTSPAWPGNTAI---------------- +----------------------------------------------------------KTAIHDFL--GDQTYTEKPGHIF----TLNADLSAITCEEYDGLYITGGRA-PEYIRLDPTIIAVTRWFMQHNKPVAAICHGIQVLTAA-------NVLQGRKLTAYPAVGP-------------------DISLAGGTYVALE---PTEAMTDGNLVTSPAWPGNTAI---------------- +----------------------------------------------------------KTAIHDFE--GDQTYSEKPGHLF----ILNATFDDVSAEDYDGLYLTGGRA-PEYIRLDPKVISITKYFMNNNKPVAAICHGIQVLTAA-------DVVKGRTLTAYPAVGP-------------------DVTMAGGNFQNVD---VDKAVVDGNLVTSPAWPGNTAI---------------- +----------------------------------------------------------KTSIHDFE--GHQTYTEKLGHNF----LLNMSFDYLKLEEYDGLYITGGRA-PEYLRLNTRVIDIVKYFMELKKPVAAICHGIQILTAA-------DIIKGRKLTAYPAVKP-------------------EVVMAGGIFIDKN---PDETVVDGNLITAPVWPGNTAI---------------- +----------------------------------------------------------KTAVHDFL--GDQTYTEKPGHNF----ALTADFDTVNTADYVGLFITGGRA-PEYIRLNPRVIEIVQEFFAAKKPVASICHGPQILTAA-------GVLKGVKATAYPAVGP-------------------DITLAGGTYVEVP---ADQAVVDEQLVTAPAWPGDTAI---------------- +----------------------------------------------------------TTAIHDFE--GEQTYSEKRGHNF----ALTADFDKVNTADYNGLFITGGRS-PEYLRLTPRVIEIVKEFFEANKPVAAICHGPQILTAA-------GVLKGKKATAYPAVGP-------------------DITLAGGTYVAVD---ADKTVVDGNLVTSPAWPGDAAI---------------- +----------------------------------------------------------RTAIHDFE--GEQTYSEKRGHNF----ALTADFDAVNTADYAGLFITGGRS-PEYLRLTPRVIEIVQEFFAANKPVAAICHGPQILTAA-------NVLKGKKATAYPAVGP-------------------DITLAGGEYVAVD---ASEAVVDGNLVTAPAWPGDSAI---------------- +----------------------------------------------------------ATAVHDFL--GEQTYTELRGHNF----ALTASFEDVKTEDYEGLFITGGRA-PEYIRLNPRVIEITKEFFAANKPVAAICHGPQVLTAA-------GVLEGYTATAYPAVGP-------------------DISLAGGIYKEVD---VSEAVVDRNLVTSPAWPGNTAI---------------- +----------------------------------------------------------ATAVHDFL--GEQTYTELRGHNF----ALTADFDAVKTEDYEGLFITGGRA-PEYIRLNARVIEIVKEFFAAGKPVAAICHGPQVLAAA-------GVLEGYKATAYPAVGP-------------------DVVLAGGEYVEAG---MDEAVVDRNLVTTPAWPGDTAI---------------- +----------------------------------------------------------KTAIHDFE--GDQTYTEKPGHLF----KLTKTFDEVDFDDYVGLFITGGRS-PEYIRMNHKVISLVKCFVRSGKPVAAICHAAQVLTAA-------DVVCGRKLTCYPALAA-------------------EVKLAGGNYIEVA---PDEAVVDCNLITSPAWPGNTAI---------------- +----------------------------------------------------------KTAIHDFE--GDQTYSEKPGHNF----AITYDFDQVVVDNYVGLVIPGGRA-PEYIRLNEKVLNIVRGFAANNKPIASVCHGQQVLAAA-------GVLEGKLCTAYPAVKP-------------------DVVRAGATWGEIT---FTNAYVDGNLVTAAAWPGHPEW---------------- +----------------------------------------------------------KTAVHDFT--GEQTYSEKVGHNF----AITIDFEKIDPEDYDGLVIPGGRA-PEYIRLNERVLEIVRHFAERKKPIAAICHGPQVLAAA-------NVLKGKKCMAYPAVKP-------------------DIISAEAEWAQPT---FTSACVDGNLVTAAAWPGHPEW---------------- +----------------------------------------------------------KTAVHDFE--GDQTYSEKRGHNF----AITFNFDDVKVDNYDGLVIPGGRA-PEYLRLNSRVIEIVKEFANKKKPIASICHGQQILVAA-------DVLNGITCTAYPAVMP-------------------DVVKAGAKWEEVT---FTNAVVSGNFVTAPAWPAHPEW---------------- +----------------------------------------------------------RTAIHDFE--GDQTYSEKPGHNF----AITYDFDKVVVDDYVGLIIPGGRA-PEYIRLNERVLEIVREFSAKHKPIASVCHGQQVLAAA-------GVLEGKLCTAYPAVKP-------------------DVLRAGAAWGEVT---FSNAYVDGNLVTAAAWPGHPEW---------------- +-MSKTALVILA------------PGGEEMEFVIAADVLRRAGVKVTVAGLLGGAVKCSRDVC----------------------IVPDTSLDIAKGSIYDAIVLPGGLGGAKAMSENAELGALLKEQEAAGRIVAAICAAPTALVAH-------GIGTGKSLTSYPSVKK-------------------QLEDA-YQYVD-----DQKVVQDGNLITSRGPGTAFDFGLKLAEVL-------- +-MSKTACVILA------------DGAEEMEFVIAADILRRTGINVTVAGLSGDPT------------------------------------------DFDVIVMPGGLGGSKAMASSSLVGEILKRQESGGRFIAAICAAPIALKSH-------GIANGKKITSYPSFKN-------------------DLCEA-YCYDD-----QSKVVQDGQLITSRGPATAFDFGLKIASAL-------- +-MSKTALIILA------------PGAEEMEFVISADVLRRAGVKVTVAGLSGTPVKCSRDVV----------------------ILPDTSLEASKSNKYDVVILPGGLGGSKAMAESAVVGEILKQQETEGRIVAAICAAPTALAAH-------SICQGKSLTSYPSVKS-------------------QLETV-YKYID-----DQAVVQDGNLITSRGPGTAFEFGLKIAEVL-------- +-ADKSALVILA------------EGAEEMEAVITIDVLRRAGVKVTVAGLIGCPVKCARQTI----------------------ITPDVALSDVAGNKFDVVALPGGQPGSNTLARSDLVGKIIQEHHKNGRFIAAICAAPIALKSH-------GIATGCALTSHPVVEK-------------------ALVDAGYKYST-----DR-VVVSDKIVTSRGPGTAFDFALKLVELI-------- +-MSKTALVILA------------PGSEEMEFVIAADVLRRAGVKVTVAGLAGVAVQCSRDVC----------------------IVPDTSLDIAKGGLYDAIVLPGGLGGAKAMSESAELGALLKGQEAAGRIVAAICAAPTALLAH-------GIGSGKNLTSYPSVKD-------------------KLVDT-YKYVD-----DQKVVQDGNLITSRGPGTAFDFGLKLAEVL-------- +-MSKTALVILA------------PGSEEMEFVIAADVLRRAGVKVTVAGLSGVAVKCSRDVC----------------------IVPDTSFDIAKGGIYDAIVLPGGLGGAKAMSESAELGALLKEQEAAGRIVAAICAAPTALLAH-------GIGSGKNLTAYPSVKG-------------------KLKDA-YKYID-----DQNVVQDGNLITSRGPGTAFDFGLKLAEVL-------- +-MPKTALIVLA------------EGAEEMEFVISADVLRRAGIKVTVAGLSD-PVKCSRDVV----------------------INPDTSLEKVKDEEFNVIVLPGGICGCEEMSKSDILGELLKKQEKEERFVAAICAAPTVLAAH-------SIGLGKTLTSYPGLKP-------------------KLDSL-YKYVD-----DEKVIQDGKLITSRGPGTAFDFALKISEVL-------- +-MSKTALVILA------------NGAEEMEFVIAADTLRRAGIAVTVAGLAGSPVKCSRDVV----------------------IVPDTSLESVKATKFDVVILPGGLGGSKALAASAMVGEILKQQEKENRIVAAICAAPTALAAF-------DIGKGKSLTSYPSFKS-------------------QLESH-YKYID-----DQKVVQDGNLITSRGPGTAFDFGLKIAEVL-------- +-MTKKLLMLLP------------HGAEEMEFVICVDVLRRCGVNVTVAGLSD-TVKCSRDVV----------------------IQADTTLEEAANDDFDAIALPGGLGGSKAMAGSTKLGEVLKSFESKGKLIAAICAAPTVLLTH-------SVALGKTLTSYPSFKD-------------------EFAGK-YTYVE-----DKTVVVDGNLVTSRGPGTAFDFALKLGEIL-------- +-MSKTALLILS------------EGAEEMEAVISADVLRRAGIKVTIAGLQGAPTKCSRDVV----------------------IVPDISIQDAAKENYDVVILPGGLKGAESLAQSDIVKGILQSQEKNGRLIAAICAAPIVLKSH-------SIGTGKSITSYPSKKQ-------------------ELSTGEYTYL------EKRVVVDEQLITSRAPGTAFEFALAIVEYL-------- +-LKKRALALLA------------AGSEEMELVVAFDVLRRCDIDVTVALVQGGVARCSRNVN----------------------VQADVTLAKYVATLPDAIILPGGLEGSRLMAQAPAVGELLRHYESETKIVAAICAAPTVFAAH-------GSFGGRRLTSYPAFKD-------------------TLTGAGYAWQE-----PGRVVRDGNLITSMGPATSFDFALTVGAAL-------- +-ATKRALALIA------------RGSEEMELVITVDVLRRCNVEVTVALVQEAVACCSRGVN----------------------VKADTTLQAYVDGLPDAIILPGGLEGAKAMAQAPAVGALLERQARVGKLVAAICAAPTVLAAH-------GKFAGRRLTSYPSFRE-------------------KLQADGYRWEE-----PGRVVRDENLITSLGPATTFDFGLAIGAAL-------- +-LKKRALALLA------------AGSEEMELVVAVDVLRRCDIDVTVALVQDEVARCSRNVN----------------------IQADVTLAKYLASLPDAIILPGGLEGSRLMSKAAAVGELLRHYQS-AKIVAAICAAPTVFAAH-------GNFAGRRLTSYPAFKD-------------------SLNGAGYAWQE-----PGRVVRDGNLITSMGPATSFDFALTVGAAL-------- +-GVKVVMIIAH------------ENFRDEELLETREELLDAGASVAVASSSRTPATGMLGAR----------------------VTPDKTLQEIRVDDYDAVIFVGGTGAQEYFSNRQALD-LARQAYEKGKIVGAICIAPSILARA-------GILRGKRATCWSGESG-------------------TLLANGATYTG------RPVERDGRIITANGPSAARQFGRALVEAL-------- +-CMKKVAVLLA------------PGFEEAEAIVTIDILRRLQIEVETLACAESAVVSYHDVP----------------------MVTDSTLAARQTDLYDAVVLPGGPQGSVNLAASKAVIQFIARHDEAGKLICPVCSAAARVLGG-------NGLKGRRYVCSGDLWQ-------------------NVTDGEY----------APIVEDGNLISGKGLGHIFDFALTLAARL-------- +-MSKKVLIPLA------------QGFEEAEFIGIADVLKRAKELNP-----DLLVKGANGIS----------------------IKADCSIEDVDIENLDAIALAGGFEGMMNLKNSNVILNIIKQLHSKNKIVAAICASPIVLNEA-------GVE--GEFACYPSCEV-------------------GLNGN------------KAVVVNKNVITSAGPATAILFGLELAKKL-------- +-RGKRIAILAA------------DGVERVELEQPRQALQDAGATTVLLSLHEGDEAG----T----------------------FPVDALVK---ADEYDALLLPGGTVNPDQLRVDTDAVGFVRDVMAADKPVAAICHGPWTLIEA-------GVAKGRTLTSYPSIRT-------------------DLRNAGANVVD------EEVARDGNLITSRSPEDLPAFNAAMIELF-------- +-MARKLLMLV----GDFVE--------NMETFGPFHCLIMLGFQVDVVCPGKKKGDKVATAVHDFT--EYQTYIEKTGHNF--TLN--ATFDEIDPRDYEGIFIPGGRA-PEYLRMDEKVLEVVRHFLEANKPLATVCHGPQILVAV-------GGIQGRKMTCYSACAV-------------------ELKLAGAEYVNAP---VEDAVVDGNIVSGVAWPSNPYVLKKF------------ +----------------------ADGFEKAELVIPLRALERAGAEVHVVSLHRGRIR--GLNLHL----------------PAGRVRVDKTITHADPAEYDGLLLPGGFISPDLLRQSADARAFVRAFAVSGRPVVTLCHGPWVLASA-------GLLEGRTLTSWPGIRD-------------------DVVHAGATWRD------QEVVRDGNLTTSRGPQDMAAFLPAMLDA--------- +----------------------ADGFEKVELVIPMKALQAAGAKVDVISLRHGNIR--GVNLHE----------------PASRVHVNKTIAEANPDDYDGLLLPGGFINPDLLRQSAEAREFVRAFDRAGKPIASLCHGPWVLASA-------GLLQGRTLTSWPGVRD-------------------DLVNAGATWLD------QEFVRDGNLATSRGPQDLIPFVKGCLDL--------- +----------------------ADGFERVELVIPLRALKRAGAGVDVVSLRHGRIR--GVNLHM----------------PATRVGVDKTISETDPAAYDGLLLPGGFISPDLLRQSAEAREFVRAFAATDRPIVTLCHGPWVLASA-------GVLVGRTLTSWPGIRD-------------------DLVNAGATWWD------RQVVRDGNLTTSRGPQDMAAFVPAMLEA--------- +----------------------ADGFEKVELVVPLRALQLAGANVDIVSLRRGRIR--GVNLHM----------------PASRVGVDKLVTEADPDAYDGLLLPGGFINPDLLRQSAAARDFVRAFDHSGKPIVTLCHGPWVLASA-------GLLKGRTLTSWPGIRD-------------------DLVNAGATWLD------REVVRDRNLVTSRGPQDMRAFLPAMLDI--------- +----------------------ADGFELVELVVPVKALKAAGATVDVISLRKGRIL--GMNLHQ----------------PAGRVRVTRTLDEAQAREYDGLLIPGGFINPDLLRQSERARAFVRAFDQAGKPIATLCHGPWLLASS-------GLLEGRTLTSWPGIRD-------------------DLVHAGATWLD------QEVVRDGNWVSSRGPQDLTAFVAAALDH--------- +----------------------ADGFEQIELTVPMKALRAAGATVDVVSLRHGKIR--GMNLHE----------------PGARVRVDRTLGEADPAEYDGLLLPGGFINPDLLRQSEEARRFVRAFDDLRKPIATICHGPWVLASA-------ELVSGRQLASWPGIRD-------------------DIVHAGGVWRD------EEAVRDGNWLSSRGPQDLPAFVREMLDL--------- +----------------------ADGFEAAELFVPLRALKRAGATVDVVSLRRGRIR--GMNLHL----------------PARRIGVDTTVGEADPGEYDGLLLPGGFINPDLLRQSAAAREFVRGFAAGNRPVVTLCHGPWVLASA-------GLLEGRTLTSWPGIRD-------------------DVVNAGATWLD------QEVVRDGNLTTSRGPQDLAAFVPAMLEA--------- +----------------------ADGFEKVELEVPLKALRLAGATVDVVSLRPGRIR--GVNMHE----------------PAGKVQVTMTVQEADPKNYEGIFIPGGFINPDLLRQSAEAREFVHSFDVSGKPIATICHGAWVLASA-------GMLRGRTITSWPGIRD-------------------DVVNAGAIWLD------QAVVRDGNLITSRGPQDLMDFVPAIIDA--------- +----------------------ADGFEKIELTAPVAALEAEGAIVDIVSLHSGSIR--GVNLHE----------------PASKVRVSKTLRKADAARYDGLLIPGGFISPDLLRQSAEARAFVRAFDERRKPIATLCHGPWVLASA-------GLTAGRTMTSWPGIRD-------------------DIVNAGATWLD------AEVVRDGNLVTSRGPQDIIPFVRAMTEL--------- +----------------------ADGFEKVELVVPVRALEAAGARVDVVSLRRGRIR--GVNLHM----------------PASRVRVDATVDDADPGDYDGLLLPGGFINPDLLRQSAPARAFVSAFAARGKPIATLCHGPWVLASA-------GLVDGRTLTSWPGIRD-------------------DLVNAGATWLD------QELVRDGNLTTSRGPQDMAAFVPGMLDT--------- +----------------------ADGVEQAELDIALAALKEADAQVTLLALRTGRIR--GMHGHQ----------------PGDLVRVDRKVDGALAADYDGLLIPGGYISPDLLRQSAAARDFVRGFDAAARPIAAMSHAAVVLVST-------GLAAGRTLTSWPGVRD-------------------DLVNAGATWCN------KETVRDGRLLTSRTPQDAAAFVRELLPF--------- +MPSKRILIVLSDAN-YFPLVDQPSGFFLMELAKPLQKLLDAGHEVTFASPEGREQPDPNSESLAFA----GNFYERRENELLNGFTKPRKLNSIELKNFAGVFIPGGHAPLADLGDNKDLGRILEYFHKENKPTAAICHGPYALLSTKV-SGGEFAYKGYKITSWSNAEEKVMES--MLGGE-VEKVETALMNAGAEMVEGAKEKVGQTTLHRELLTGGNPMAADELGNRFV----------- +--KWKILLIATQE-RYLKMKFFSTGNHPVEMLLPLLHLDAAGFEIDIATISGDPVKLEMWAFPQE-DEAVKGIYEK----YKEKIRSPLNLHDVKDTPYIGTFIPGGHGAMNDIPFSETVGKILRWGDENQRFLITLCHGPAGMLAADVPKGSKFIYDGYEIVVFPDSLDTNANVIGYIPSKMPWYVGERLRKLGITLRNN--SITGETHRDRYVITGDSPLASNNLGKLAANA--------- +MPAKKVLIILSDADSFPLKVDQPSGFFLMELAKPLQKLLDAGYEVTFASPKGQPTPDPNSESLLAFA---GNFYERREHELENGFSHPRTFSSIELDSFAGVFIPGGHAPLRDLGADPHLGRILRFFHAKSRPTAAICHGPFAFLSTKLAGEGDFVYKDYRITCWSDAEEKMMEMGGEI-----EKVESDLRNEGAIMVEGVKEKIGSVTVDR------------------------------ +--GQAVLFLC----ADQFA--------RGRRG----------LPRRAACPTKRKGEACVTAIYDAT--PAAASDERRGHNF----AVTADWGDVDADRYACVVVPGGRA-PELLATRGEAVALVREFAGKGKVVASIDQATSSSPRR-------GSSTAGA----ARAAS-------------------RRGWSPASPRR-----ASGTVARSPTG--SS----------------------- +--RLTRPLST----QDYVD--------DYEANVPFRALAGVGCRVEAACPTKRKGEACVTAIYDAT--PAAASDERRGHNF----AVTADWGDVDADRYACVVVPGGRA-PELLATRGEAVALVREFAGKGKVVASIDQGHLLLAAV-------GLLDGRSCASGVATRV-------------------VAGLAGAASVR-----HGGAVADGKLVTAASWPDLAEFIA-------------- +--GQRVLILC----ADYVD--------DYEANVPFRALAGVGCRVESACPTKRKGETVVTAIYDAAGPAVTVSEERRGHNF----VVTADWADASADDFDCVVIPGGRA-PELLVTHDRAVALVKEFADKGKVVASIGHGHLLLAAA-------GLLRGRKCASGVPMRV-------------------VSRLAGAEAVE-----AAAAVVDGRLVTAASWTDLAQFVA-------------- +--GQAVLFLC----ADYVD--------DYEANVPFRALAGVGCRVEAACPTKRKGEACVTAIYDAT--PAAASDERRGHNF----AVTADWGDVDADRYACVVVPGGRA-PELLATRGEAVALVREFAGKGKVVASIDQGHLLLAAV-------GLLDGRSCASGVATRV-------------------VAGLAGAASVR-----HGGAVADGKLVTAASWPDLAEFIA-------------- +--DKRILFIC----GDYME--------DYEVMVPFQSLQALGCHVDAVCPKKGAGEKCPTAIHDFEGQ---TYSEKPGHDF----TLTASFEGLDASIYDALVIPGGRA-PEYLALDEEVITLVKKFMNGGKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVVLGGATWLEPD--PIDRCFTDGNLVTGAAWPGHPEFIS-------------- +--DKKILFLC----GDYME--------DYEVMVPFQSLQALGCHVDAVCPDKGAGEKCPTAIHDFEGQ---TYSEKPGHDF----TLTASFESVDASSYDALVIPGGRA-PEYLALNDKVISLVKAFADNGKPIASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVVLGGGTWLEPD--PIHRCFTDGNLVTGAAWPGHPEFVS-------------- +--NQRILFLC----GDYME--------DYEVKGPFQSLQALGCQVDAVCPEKKAGDRCPTAIHDFEGQ---TYSEKPGHTF----ALTASFDGLNSSSYDALVIPGGRA-PEYLALNEHVLTIVKEFMISEKPVASICHGQQILAAA-------GVLKGRKCTAYPAVKL-------------------NVVLGGGTWLEPD--PIHRCFTDGNLVTGAAWPGHPEFVS-------------- +--NKRILFLC----GDYME--------DYEVKVPFQSLQALGCQVDAVCPEKKAGDRCPTAIHDFEGQ---TYSEKPGHTF----GLTATFDGVDSSSYDALVIPGGRA-PEYLALNQHVLNVVKEFMSSGKPVASICHGQQILAAA-------GVLKGRKCTAYPAVKL-------------------NVVLGGGTWLEPD--PIHRCFTDGNLVTGAAWPGHPEYVS-------------- +--GKRILFLC----GDYME--------DYEVMVPFQSLEALECRVDAVCPGKRAGDKCPTAVHDFEGQ---TYSEKPGHNF----TLTADFEGIDASSYDGLVIPGGRA-PEYLALNDNVIKLVKEFMESGKPVASICHGQQILSAA-------GLLKGKKCTAYPAVKL-------------------NVVLGGATWLEPD--PIHRCFTDGNLVTGAAWPGHPEFIA-------------- +--GKRILFIC----GDYME--------DYEVAVPFQSLQALECHVDAVCPGKHAGDTCPTAVHDFEGQ---TYSEKPGHNF----ALNADFEGVNASSYDGLVIPGGRA-PEYLALNARVLELVRGFMESGKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVVLSGATWVEPD--PIHRCFTDGNLVTGAAWPGHPEFIA-------------- +--DKKVLMLC----GDYME--------DYEAMVPFQAMQALGYQVDAVCPDKKSGDTCATAVHDFEGQ---TYSEKPGHNF----ALTATFSEVKVQDYDALVVPGGRA-PEYLSLNEKVLDLVREFDDAKKPIASICHGQQILAAA-------GVLKGKKCTAYPAVKS-------------------HVVLSGGQWLEPE--PISKCFTDGHLVTGAAWPAHPEFVA-------------- +--KKRILLLG----GDSMA--------EYDGIVPFQSLQVVGCEVHAVCSNKTKDKFCPTAVHEYEGN--SNFSEKPGLDF----RMTADFDGINPLCYDGLVIAGGRA-PEYYALDDKVLVLVQKFVDLAKPIASIGYGQLILAAA-------DVLKGRKCTAHPCAKV-------------------NVELAKAIWLEPK--PKSRCYTDGNLVTGSGWQGHPELIC-------------- +--DKKILFIC----GDYME--------DYEVKVPFQSLQALGCHVDAVCPSKKAGDTCPTAVHDFEGQ---TYSEKPGHTF----ALTATFDDVDPSGYDALVIPGGRA-PEYLALNESVIALVKYFFENKKPVASICHGQQILSAA-------GVLKVLLL--------------------------------------------------------------------------------- +--DKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVDAVCPRKKAGDSCPTAVHDFEGQ---TYSEKPGHHF----TLTASYEELDASSYDALVIPGGRA-SEYLALDDTVITLVRDFMESKKPVASICHGQQILAAA-------GVLKGRKCTAYPAVKL-------------------NVVLSGATWLEPD--PIDLCCTDENLVTGAAWPGHPQFIS-------------- +--KKKILFIC----GDFVE--------DFQAKVPFQSLQSLGCHVDAICPSKFAGDFCPTAVHDFEGQ---TYSEKHGHHF----DLTVAFDDVDPSDYDALVIPGGRS-PEYLSLMDPVLDLVRHFFLNNKPVGSIGHGQQILAAA-------GVLKGRKCTAYPDVKL-------------------HVVLSGATWLEPD--PISRCFTDGNLVTGAAWQGLPEFIA-------------- +--DKKILFIC----GDYME--------DYEVKVPFQSLQALGCHVDAVCPSKKAGDTCPTAVHDFEGQ---TYSEKPGHTF----ALTATFDDVDPSGYDALVIPGGRA-PEYLALNESVIALVKYFFENKKPVASICHGQQILSAA-------GVLKGRKCTAYPAVKL-------------------NVVLSGATWLEPD--PISRCFTDGNLVTGAAWPGHPEFIA-------------- +--DKNILFLC----GDYME--------DYEVIVPFQSLEALGCKVDAICPSKKPGETCPTAIHDFEGQ---TYSEKPGHQF----TLNASFEDALYSSYHGLVIPGGRA-PEYLALHDAILGLVNQFMKDKKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVVLGGGEWMEPE--PIDRCFTDGNLVTGAAWPGHPEFIS-------------- +--PKRILFLC----GDYME--------DYEVIVPFQALQALGCVVDGVCPNKDSGENCLTAVHDFEGQ---TYSEKPGHDF----TLTAKFETVDVSTYDGLVIPGGRA-PEYLAMDDKVITLVREFMEKEKPVASICHGQQLLSAA-------EVLKGRKCTAYPAVKV-------------------NVVLSGATWLESD--TVFRSFTDGNLVTAGAWPAHPEFIS-------------- +--KKKVLMLC----GDFME--------DYEAMVPCQTLQAVGYTVDSVCPGKKAGETVATAVHDFEGQ---TYSEKPGHNF----PLTATFDAVKVEEYDALVIPGGRA-PEYLSLNDKVLRLVREFDTSSKPIASICHGQQILAAA-------GVLQGKKCTAYPAVKP-------------------QVVLSGAQWIEPD--PITMAHTHGKLVTAAAWPAHPEFVA-------------- +--DKKILFIC----GDYME--------KYEVKVPFQSLQALGCHVDAVCPLSMGDCTGPTAFHYLEWQ---TYSAKPGCII----SLPEAVNDFDHRGYDPYMSRQRRT-TVWMALSESVIDLVKYFSSCKKLVTQQCHVCHISAAS-------NVFKGRKCTAGMAVKL-------------------YVVLSGTTWLEPD--PISRWFTDGNLVTGGAWPGPPEFIF-------------- +--GKHILFIC----GDYME--------DYEVMVPFQALQSLGCNVAVVCPGKNVGDTCPTAVHDFEGQ---TYSEKPGHNF----TLNAKFEDVKVENFDALVIPGGRA-PEYLALNEKVISIVKNFEEKKKPIASICHGPQILASA-------DVLKGKKCTAYPAVKL-------------------NVVLAGAEWLEPD--PITTCFTDGNLITAAAWPAHPQFLS-------------- +--GKHILFLC----GDFME--------DYEVMVPFQTLQALGCSVDAVCPDKNIGDKCPTAIHDFEGQ---TYSEKMGHNF----ILNANFEDVTVENYDALVIPGGRA-PEYLALNEKVLSIVKQFEEKKKLIASICHGQQILAAA-------DVLKGKRCTAYPSVKL-------------------NVLLSGADWLEPE--PITTCFRDGNLVTAAAWPAHPQFIS-------------- +--AKRILFIC----GDFME--------DYEVMVPFQSFQALECHVDAVCPNKGAGDKCATAVHDFEGQ---TYSEKPGHDF----TLTADFGAVDASSYDALVIPGGRA-PEYLALNESVIKLVKHFMESGKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVVLSGASWLEPE--PIDRCFTDGNLVTGAAWPGHPQFIS-------------- +--GKRILFLC----GDFME--------DYEVKVPFQSLQALECHVDAVCPKKKAGEKCPTAVHDFEGQ---TYSEKPGHDF----TLNANFESVDVSSYDGLVIPGGRA-PEYLALDDDVIKLVQEFMESKKPVASICHGQQILSAA-------GVLKVSISVNI--------------------------I--------------------------------------------------- +--DKRILFLC----GDYME--------DYEVMVPFQSFQALECHVDAVCPKKKAGETCPTAIHDFEGQ---TYSEKPGHDF----TLTATFEDLNIPSYDALVIPGGRA-PEYLALNEKVIALVKEFMEAGKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVVLSGATWLEPE--PIDRCFTDGNLVTGAAWPGHPEFIS-------------- +--GKRILFLC----GDFME--------DYEVKVPFQSLQALECHVDAVCPKKKAGEKCPTAVHDFEGQ---TYSEKPGHDF----TLNANFESVDVSSYDGLVIPGGRA-PEYLALDDDVIKLVQEFMESKKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVILGGATWLEPE--PIDRCFTDGHLVTGAAWPGHPEFIS-------------- +--DKRILFLC----GDFME--------DYEVMVPFQSLQALGCHVDAVCPKKQKGDTCPTAVHDFEGQ---TYSEKPGHDF----TLNATFEGIDASSYDGLVIPGGRA-PEYLALDENVIAIVKSFMKAEKPVASICHGQQILSAA-------GVLKGMKCTAYPAVKL-------------------NVVLGGATWLEPD--PINRCFTDGNLVTGAAWPGHPEFVS-------------- +--RQGVLVLC----GDYVD--------DYEANVPFRVLAGVGCRVETACPTKRKGEACVTAIYDDDAG-----KEKRGHNF----VVTVDWDDVHMDDYECVLLPGGRS-PELLVTNDKAVALVAEFAARGKLVASIDQGHLLLAAA-------GLLKGKRCASGVPMRV-------------------IASLAGAIAVE-----AKGAVADGKLVTAASWPDLAQFIA-------------- +--GQRVLVLC----ADYVD--------DYEANVPFRALAGVGCRVESACPTKRRGEPCVTAIYDAVKG--AVSEERRGHNF----AVTADWADASADGFDCVVVPGGRA-PELLVTHESAVALVREFADKGKVVASIGQGHLLLAAA-------GLLRGRRCASGVPMRV-------------------VSRLAGAEVVE-----TEGAVADGKIVTAAGWPDLAPFVA-------------- +--GQGVLFLC----GDYVD--------DYEANVPFRALAGVGCRVEAACPTKRKGEACVTAIYEDVAAPGTVSDEKRGHNF----AMTVDWADIDVDDYECVVVPGGRS-PELLVTKEEAVALVAKFAAKGKVVASIDQGHLVLAAA-------GLLKGKRCASGVPMRV-------------------ISNLAGAVGVE-----AEGAVADGKLVTAASWPDLAEFIA-------------- +--DKRILFLC----GDFME--------DYEVTVPFQSLQALGCHVDAVSPKKKAGDICPTAVHDFEGQ---TYSEKPGHNF----ILTASYEGLDASTYDALVIPGGRA-PEYLALDETVIALVKEFMQSRKPVASICHGQQILAAA-------GVLKGRKCTAYPTVKL-------------------NVVLGGATWLEPD--PIDRCYTDENLVTGAAWPGHPEFVS-------------- +---NSVLFIC----GDYVE--------DYEINVPFRALQALGCKVDAVTPSKKRGETCVTAIHDD-EA--QVFSEKRGHNF----FITANWDDISVHRYDCIVVPGGRS-PELLVMNEKVVNLVKEFAEKDKVIAGIGQGQWLLAAA-------GIVKGKRCATNNGMKV-------------------MVKMAGGDLEE-----SKGCVSDGKLVTAAGWPDLPAFIS-------------- +---NSVLVLL----ADYVE--------DYEVNVPFRALQGLGVKVDAVCPSKRKGESCVTAIHDD-EA--QICSEKRGHNF----VVNANWSEISVDDYDCLVLPGGRS-PELLVVNEKVVSLIKEFSSKDKIIAAIGQGKWLLAAA-------GALKGKKCASSHGMKA-------------------IVKVAGGEVVE-----SDGCVKDGKLVTASGWPSLPAFLT-------------- +---NSVLFLC----GDYVE--------DYEFNVPFRALQAVGCKVDAVTPSKKKGETCVTAIHDD-EA--QAFSEKRGHNL----VITANWSDVSVYDYDCLVVPGGRS-PELLVMNDKAVTLVKEFAEKNRVIAGVGQGQWLLAAA-------GVLKGKRCACGDGMKV-------------------MVKIGGGELEE-----SKGCVSDGKLVTAVGWPALPSFIS-------------- +--QPSLLFLI----GDCVE--------DYSINVPFKAFQALGCKVDAVSPNKKKGDKCATIVHDLEER--QLPTEKSSHNF----YVTVAWEDVSVDDYDCIVVPGGRS-PELLVMNDKAVGLIKKFVEKGKFVAAIGMGNWLLAAT-------GALKKKRCASGYGTKV-------------------AVKVAGGQILE-----SEQCVTDDKLVTAATTSDLPAFVH-------------- +--QPSLLFLI----GDCVE--------DYSINVPFKAFQALGCKVDAVTPNKKRGEKCATIVHDLEDR--QLPTEKSGHNF----YVTIGWDDVSVDDYDCIVVPGGRS-PELLVMNPKAVELVRTFVEKGKFVAAIGMGNWLLAAT-------GTLKKKRCASSYGTKV-------------------AVKVGGGEIVE-----SERCVTDEKLVTAAETSDLPAFMY-------------- +--DKRILFLC----GDYME--------DYEVAVPFQSLQALECHVDAVCPKKKAGDSCPTAVHDFEGQ---TYSEKPGHNF----TLTANFESVDVSGYDALVVPGGRA-PEYLALNENVIALVKDFMEAKKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVLLAGASWLEPD--PINRCFTDGNLVSGAAWPGHPEFIS-------------- +--DKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVNAVCPKKKAGDSCPTAVHDFEGQ---TYSEKPGHHF----TLTASYVGLDVSSYDALVLPGGRA-PEYLALDETVIALVKQFMQSKKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVVLSGATWLEPD--PIDRCYTDENLVTGAAWPGHPEFIS-------------- +--DKRILFLC----GDYME--------DYEVTVPFQALQALGCHVDAVCPKKKAGDSCVTAVHDFEGQ---TYSEKPGHNF----TLTANFDGLDVSSYDALVIPGGRA-PEYLALDKTVLAIAKHFMEAKKPVASICHGQQVLAAA-------GVLKGKKCTAYPAVKL-------------------NVVLSGAIWLEPD--PIHRCFTHENLVTGAAWPGHPEFLQ-------------- +--NKRILFLC----GDYME--------DYEVMVPFQSLQALGCHVDAICPDKGAGEKCPTAIHDFEGQ---TYSEKPGHEF----ALTASFDNVDASSYDALVIPGGRA-PEYLALNDKVISLVKGFMEKAKPVASICHGQQILSAA-------GVLQGRKCTAYPAVKL-------------------NVVLGGATWLEPN--PIDRCFTDGNLVTGAAWPGHPEFIS-------------- +--PASVLFLI----GDYVE--------DYGVNIPFRALQALGCKVDAVTPNKKKGEVCATAVYDFEER--QIPAEKRGHNF----FVTASWDDVCVDDYDCVVVPGGRS-PELLVMNEKAIALVKKFAEKNKVFAAIGQGKLLLAAT-------GVLKGKRCASGKGMKV-------------------TVKVAGGEAVE-----SKGCVTDGKLVTAASVSDLPAFLS-------------- +--GKKILVLC----GDYME--------DYEVMVPFQALLSYGFTVHAVCPGKKSGDVCRTAVHDFEGQ---TYSEKPGHNF----ALNADFEQVKAEEYDGLVIPGGRA-PEYLALDDKVIKLVQDFASSKKPIASICHGQQILAAA-------GVLSGKKCTAYPAVGP-------------------ACKLAGAQWVDAN--PIDLAVTDGHLVTAAAWPGHPEFIK-------------- +--NKRILFLC----GGYME--------DYEVTVPFQSLQALGCHVDAVCPDKGAGEKCPTAIHDFEGQ---TYSEKPGHDF----ALTASFDNVDASSYDALVIPGGRA-PEYLALNDKVISLVKGFMDKAKPVASICHGQQILSAA-------GVLQGRKCTAYPAVKL-------------------NVVLGGGDMAGAQ--SHRPLLHRPCDRSGMAWPPGVHLPA-------------- +--DKKILFLC----GDYME--------DYEVMVPFQALQALGCHVDAVCPDKGPGDKCPTAIHDFEGQ---TYSEKPGHDF----PLNASFDGVDASSYDALVIPGGRA-PEYLALNEKVLSLAKGFMDKGKPVASICHGQQILAAA-------GVLQGRKCTAYPAVKL-------------------NVVLGGGTWLEPD--PIHRCFTDGNLVTGAAWPAHPEFVA-------------- +--EKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVDAVCPKKKSGDTCPTAIHDFEGQ---TYSEKPGHDF----TLTADFEGLDASSYDALVIPGGRA-PEYLALDGKVIALVKDFMEAKKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVVLAGATWLEPD--PIDRCFTDGNLVTGAAWPGHPEFIS-------------- +--KKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVDAVCPKKKAGDTCPTAVHDFEGQ---TYSEKPGYDF----TLTANFEGIDASSYDALVIPGGRA-PSYLALDETVIALVKKFMESRKPVASICHGQQILAAA-------GVLKGMKCTAYPAVKL-------------------NVVLAGATWLEPD--PIHRCFTDGNLVTGAAWPGHPEFIS-------------- +--DKRILFLC----GDFME--------DYEITVPLQALQALGCHVDAVCPKKKAGDICVTAVQQFEGQ---TYTEKRGHDF----TLTADYEGLEVSSYDALVIPGGRS-PEYLAVDKTVIAITKHFMEAKKPVAAICHGPQILAAA-------GVLQGKKCTAYPAVKL-------------------NVVLAGGIWLEPD--PFHRCFTHENLVTGAAWQGHPEFIA-------------- +--DKRILFLC----GDYME--------DYEITVPFQSFQALGCHVDGVCPNKKAGDTCPTAVHDFEGQ---TYSEKPGHSF----TLTADFEGLDASSYDALVIPGGRA-PEYLALNPQVIAIVKEFMEAKKPVASICHGQQVLSAA-------GVLQGRKCTAYPAVKL-------------------NVELSGATWVEPD--PIDRCFTDGNLVTGAAWPGHPQFIS-------------- +--NKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVDAVCPKKKAGDLCPTAVHDFEGQ---TYSEKPGHDF----TLTANFEDIDASSYDALVIPGGRA-PEYLALDGKVIDIAKHFMESEKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------NVVLAGATWLEPE--PIDRCFSHGNLVTGAAWPGHPEFIS-------------- +---PFVLILLSAAQRLRLNDEVTTGFWAEELVVPWQILRKAGWRLQVVTPGGVPPLDPESLDPSTLGGHSRAAYLCNAVRQITGLRTPLDLDALTLDTLIGVFIPGGNGPLMDLCQAPGVDRLLRHCVAAAKPIATLCHGTAALLATCG-GADRSPFCGQRVTCFSAAEESATPL----AGRWPYTLENRLRQEGFRVST-GAPWQSHIATDNFILSGQNPASAATLTHV------------- +APCKKVLMLC----GDYME--------DYEAAVPFYALAAFGVAVDCVAPGKKPGDACLTAVHEFL-GH-DLYTELPGHRF--AV--TADFAAADASRYDALVVPGGRF-VERLSVDPLAVSLVAAFATRRRPVVVTCHSQLLLAAA-------GAMRGVRCTAFFSMRR-------------------VVELAGGRWVEPD-PL-GLCVADGNVLSAIRWPAHGEII--------------- +APCKKVLMLC----GDYME--------DYEAAVPFYALAAFGVAVDCVAPGKKPGDACLTAVHEFL-GH-DLYTELPGHRF--AV--TADFAAADASRYDALVVPGGRF-VERLSVDPLAVSLVAAFATRRRPVVVTASAGPRTARS-------------------------------------------SGSSSAPWAAAS-PA-AAARPSSSSAP---------YL--------------- +AAPRKVLMLC----GDYME--------DFEAAVPLYALSALGITVDCAAPGKRPGDSCLTAVHDFL-GF-ELYTELTGHRF--TI--TADFAAADPSRYDALVIPGGRF-TEQLSADAAVVDLVAAFAALRRPLVLTCHSQLLLAAA-------GGSGGTRCTAFFSLRP-------------------VVELAGGAWVDPD-PF-ELCVADGHVLSAIGWPAHAQIL--------------- +APCKKVLMLC----GDYME--------DYEAAEPFYALAAFGVAVDCVAPGKKPGDACLTAVHEFL-GH-DLYTELPGHRF--AV--TADFAAADASRYDALVVPGGRF-VERLSVDPLAVSLVAAFATRRRPVVVTCHSQLLLAAA-------GAMRGVRCTAFFSMRR-------------------VVELAGGTWVEPD-PL-GLCVADGNVLSAIGWPAHGEII--------------- +-MAKKVLLLC----GDYAE--------DYEVMVPFQALQAYGVAVDAACPGKKAGDVCRTAVHQVS-GH-QTYSESRGHNF--ML--NASFGEIEVSKYDGLVIPGGRA-PEYLAMNESVVELVKKFSDSAKPIASVCHGQLILAAA-------NLVKDRKCTAYPPVKP-------------------ALIAAGAHWIEPE-TM-SKCVSDGNLITGATYDSHPEFI--------------- +MAAKKVLMLC----GDYME--------DYEVMVPFQALQAYGVSVDAVCPSKKAGNICRTAVHQGI-GH-QTYSETKGHNF--TL--NASFDEITASEYDGLVIPGGRA-PEYLAMDRQVLNLVRNFSDAKKPIASVCHGQLILAAA-------RVVENRNCTAYPAVKP-------------------VLVAAGAKWEEPD-TM-AKCTVDGNLITAATYDSHPEFI--------------- +ANSRTLLILC----GDYME--------DYEVVFFLDYLFLQSFLRLTVCPGKKSGDSCPTAVHDFC-GH-Q----------------------------------------------------------------------LILAAA-------DTVNGRNCTAYATVGP-------------------ALIAAGANWVEPT-TP-HVCVVDGSLITAATYEGHPEFI--------------- +ANSRTVLILC----GDYME--------DYEVMVPFQALQAFGVSVHTVCPGKKSGDSCPTAVHDFC-GH-QTYSESRGHNF--TL--NATFDEVDLTKYDGLVIPGGRA-PEYLAMNASVVDLVKQFSTSGKPIASICHGQLILAAA-------DTVNGRSCTAYATVGP-------------------ALIAAGAKWVEPT-TP-DVCVVDGSLITAATYEGHPEFI--------------- +ADQKRVLLLC----GDYVE--------DYEVMVPFQALSAYGLSVDAVCPGKKAGDFCRTAIHDSL-GH-QTYSESRGHNF--VL--NATFDEIDATKYDGLIIPGGRA-PEYLAMIESVTDLVKKFEHSQKPIASICHGQLILAAA-------GSVKGKKCTAYPAVKP-------------------VLVAAGAHWVEPE-TT-AYCTSDGNLITGATYDGHPEFI--------------- +---KKVLLLC----GDYVE--------DYEVMVPFQALLAYGLAVDVVCPGKKAGDICRTAIHESL-GH-QTYSESRGHNF--AL--NANFDEVDPDKYNGLIIPGGRA-PEYLAMNESVLKLVEKFDESQKPIASICHGQLILAAA-------NVVKGRKCTAYPPVKP-------------------TLISAGAHWVEPD-TM-AFCTVDGNLITGATYKGHPEFI--------------- +AKCKAVLMII----GDYVE--------DYEVMVPFQALLAYGLKVDAVCPGKKAGETCATAIHDFL-GH-QTYSESKGHNF--AL--TANFEDVDADSYDALVVPGGRA-PEYLSLDENVLNLVKKFESAHKPIASICHGQLILAAA-------GVLKDKQCTAYPAVKP-------------------VVVAAGGIWKDPS-PI-SACFTDGKLVTGAAWPGHPEFL--------------- +---------------------------MEQAIVPFQALQAYGVQVDAVCPGKMAGDVCRTVKYKAYS----TYIELPGHNF--IL--NATFDDIEVTSYDGLIIPGARG-PEYLATFELVRDVVRNFLSCKKPIAAICHALLLLTDP-------NSIRDRKCTGFPTMRP-------------------VAHAAGAQWVEPE-SR-EACVVDGNLITAALYASHPEYI--------------- +-MVKSVLLLC----GDYME--------DHEAMVPFQALLAFGVKVDAVCPGKKAGEFCRTAIHELS-TH-QTFDESRGHNF--TL--NATFDEIDFGKYDGLVIPGGRA-PEYLAMNESVLDCVRKFSDAGKPIASICHGQLILAAA-------GLVKGRRCTAAPHGRP-------------------VLIAAGADWVEPQ-NF-AACVADGNLITGATYFGHPEFI--------------- +MASKRILLLC----GDFTE--------DYEAMVPFQALQAFGLTVDTVCPGRKAGDVCRTAIHGIH-GD-QTYSEMIGHKF--VL--NATFDEVDASSYDVLWVPGGRS-PEYLSRVPGVLELVTKFVSLGKLIASTCHGPLILAAS-------GVLKGRKCTGFPSLKP-------------------VLVDAGADWVDPD-TM-TTTVEDGGFITSTTYEGQPEII--------------- +MAPKKVLLLC----GDFME--------DYEAMVPFQALQAFGLAVDAVCPGKKSGDVCRTAVHVLA-GA-QTYSETVGHNF--SL--NATFDEVDAASYDGLWVPGGRA-PEYLAHVPGVVELVTKFVSLGKQIASICHGQLILAAA-------GVVKGRTCTAFPPVKP-------------------VLVAAGAHWVEPD-TE-AATVVDGDLITAATYEGHPELI--------------- +-MGRQVLILC----GDFME--------DYEVMVPFQALQAFGVSVDSVCPGKKAGEACTTAVHERLP-H-ETYRESRGHNF--TL--NATFDDIEASKYDGLVIPGGRA-PEYLSMNESVLKLVCKFSESGKPIASICHGQLILAAA-------DVLRGKKCTAYPAVKP-------------------VAVAAGAQWVEPE-SM-AACVIDGNLITGATYMGHPEFI--------------- +-MGKKVLVLC----GDYME--------DYEAMVPFQALQAYGIQVDAACPDKISGDVCRTAIHYKSAAH-QTYSELRGHNF--TL--NATFGDLSSDDYDGLIIPGGRA-PEYLAMNDGVLDLARGFFRSGKAVGSICHGSLILAAA-------GVLKGRKCTAYPSLKS-------------------VLVDAGADWVEPE-SM-MSCFVDGNFISGATYEGHSEYL--------------- +ASSRSVLLIC----GDFVE--------DYEVMVPFQALQAYGVKVDAVCPGKKAGESCATAIHDFV-GF-QTYAELRGHNF--SL--NKDFHGVKAESYDALVIPGGRA-PEYLSLDDEVLEIVKSFHKSGKPIASICHGQLILAAA-------GILRGKKSTAYPAVKP-------------------VVVSAGGVWQEPN-PI-SKCFRDGSLITGAAYPGHPEFI--------------- +MASKRVLLLC----GDFME--------DYEAMVPFQALQAFGVAVDAVCPGKKANDVCRTAVHVLS-GA-QTYTETVGHNF--AL--NATFDEVNAASYDGLLLPGGRA-PEYLAHIPSVVELVTKFVSLGKQIASICHGQLILAAS-------GVVKGRKCTAFPPVKP-------------------VLIAAGAHWVEPE-TM-ATTVVDGNLITAATYDGHPELI--------------- +EAQKYVLMIC----GDYME--------DYEAMVPFQSLQAYGIKVDAVCPGKKAGDKCPTAVHDFL-GH-QTYSELRGHNF--VL--TATFDEIDARMYDGLLVPGGRA-PEYLALNESVLKLVKQFSDSNKPIASICHGQLILAAA-------GVLKEKVCTAYPAVKP-------------------VVVAAGGVWKDPD-PI-STCFIDGNLITGAAWPGHPEFI--------------- +EGYRSVLMIC----GDYME--------DYEAMVPFQALQAYGIKVDAVCPGKQAGDKCATAVHDFL-GH-QTYSELRGHYF--VL--TASFDDIDTSMYDGLVVPGGRA-PEYLALNESVLKLVKHFSDSNKPIASICHGQLILAGA-------GILKEKTCTAYPAVKP-------------------VIVAAGGVWKDPE-PI-STCFVDGNLITGAAWPGHPEFI--------------- +NAQKRVLLLC----GDYME--------DYEVMVPFQALLAYGVAVDAVCPGKKAGDFCRTSIHQLS-GH-QTYTESRGHNF--TL--NATFDEIETGTYDGLVIPGGRA-PEYLAMDKSVLSLAKNFADSQKPIVSICHAQLILAAA-------DSVKGRRCTAYPALKP-------------------VLIAAGAHWEEPE-TL-ASCIADGNLITGATYEGNPEFI--------------- +ANQKRVLLLC----GDYVE--------DYEVMVPFQALLAYGVAVDAVCPGKKSGDICRTAVHQLS-GH-QTYSESRGHNF--AL--NATFDEIEASKYDGLFIPGGRA-PEYLAMNESVLDLVKSFANAKKPIVAICHGQLILAAA-------DVVSGRRCTAYPAVKP-------------------VLVAAGAHWEEPE-TL-ASCTIDGNLITGSTYEGNPEFI--------------- +-MAKSVLILC----GDYME--------DYEVMVPFQALLAYGVSVHAVCPGKKAGDVCRTAVHQGL-GH-QTYSESRGHNF--TV--NATFDEVDASKYDGLVIPGGRA-PEYLAMNESVLDLVRKFFSSGKPIASICHGQLILAAS-------GSVRGRKCTAYPAVGP-------------------ALIAAGAHWVEPE-TM-SACVIDGNLITAATYIGHPGFI--------------- +ANQKRVLLLC----GDYVE--------DYEVMVPFQALLAYGLAVDAVCPGKKSGDICRTAVHQLY-GH-QTYSESRGHNF--AV--NATFDEIEATKYDGLFIPGGRA-PEYLAMNEAVLDLVKSFANTKKPIVSVCHGQLILAAA-------DVVRGRKCTAYPAVKP-------------------VLVAAGAHWEEPE-TL-ASCTIDGNLITGSTYEGNPDFI--------------- +RAQKRVLIIC----GDYME--------DYEVMVPFQALLAYGVAVDAVCPDKKAGDVCRTAIHQLA-TH-QTYSETRGHNF--TL--NATFDEIDASVYDGLVLPGGRA-PEYLAMNESVLDVVRKFSASRKPIASICHGQLILAAA-------DCVKGRKCTAFPSVKP-------------------VLIAAGAHWIENA-DM-GACVVDENLVTAATYVGHPEFI--------------- +--------------DDYME--------DYEAAVPLYALAALGVGVHCAAPGKSPGDACLTAVHDFL-GY-DLYTELPGHLF--PM--TAHFP-ADPASYDALVVPGGRS-VEPLSTDADAVSLVRAFAELRRPVLLTCHSQLLLAAA-------GAMGGVRCTAFHSMRP-------------------VVELAGGTWVEPD-PW-SLCVADGHVLTAIGWPAHAEII--------------- +APSRRVLMLC----GDYME--------DYEAAVPLYALAALGVAVDRIAPGKHPGDACLTAVHEFL-GF-ELYTELPGHRF--AV--TADFAAANPSRYDALVVPGGRF-AEHLSADEGAVALVAAFAEMRRPVVLTCHSQLLLAAA-------GGAGGVRCTAFFGVRP-------------------VVELAGGTWVDPE-PF-SLCVADGHVLSAIGWPAHAEII--------------- +APSKKVLMLC----GDYME--------DYEAAVPFYALAGLGVAVHCAAPGKAPGDPCPTAVHDFL-GY-DLYTELPGHRF--RV--TADFAAADPSSYDALVVPGGRF-VEQLSVDPEAVALVGAFAELRRPVLLTCHSQVLLAAA-------GAMAGVRCTAFFSLRP-------------------VVELAGGTWVDPD-PF-SLCVADGHVLTAIGWPAHGEII--------------- +KPQKKVLLLC----GDFME--------DYEAMVPFQALQAYGIAVDAVCPGKKAGDCCRTVIQDSGAGY-QTFTEKLGHNF--SL--NANFDEVDFSKYDGLLLPGGRA-PEYLAINESVLDCVRKFSDSGKPIGSICHGHLILAAA-------GSVKGRKCTALHALGP-------------------VLIDAGAHWIEPK-TR-MDCVADGNIITGVIYRAHPEYI--------------- +VAKKSALIIC----GDYME--------DFEVMVPFHVLQAFGVRVDCVSPTKLPGDKCITAIHDFL-GF-ELYTELPGHSF--TL--NSNFDEVEAGSYDALIIPGGRF-IERLSVDDEVLSIVRRFAEAGKPIATSCHSQLLLAAA-------GLK-GKKCTAFASMKS-------------------VIELAGGVWWEQPGDI-TACLKDGNILSSIGWPAHAEYL--------------- +ITQKSALIIC----GDYME--------DYEVIVPFFVLQSLGVRVDCASPGKRSGDKCFTAIHDFL-GF-ELYTELQGHFF--KL--NANFEEVKFESYDTLIIPGGRF-TELLSADEKVVSLVKKFAETGKPLITSCHSQIMLVAA-------GLQ-GKKCTAFTSLKP-------------------LIELAGGIWWEQPGDI-TACLKDGNLVSSIGWPGHAAYL--------------- +VVEKSALIIC----GDYME--------DFEVMVPFQVLQAFGVRVDCVSPTKLPGQKCFTAIHVSL-GF-EHYSELPGHSF--TL--NSNFNEVEVGCYDALVIPGGRF-TELFSVDDRVLSIVKAFADAGKPIVTTCHSQLILAAA-------GLK-GKKCTAFASMKP-------------------VIELAGGIWWEQPGDI-TACLKDGNILSSIGWPAHAEIL--------------- +MAQKSVLMLC----GEFME--------AYETIVPLYFLQAFSVSVHCVSPGRKTGDKCVMAAHDLL-GL--IYSELVVDHL--TL--NANFHEVIPEQYDAIIIPGGRF-TELLSTDEKCVSMVARFAELGKIILTSCHSQLLLAAA-------GIARGMKCTAFESMKP-------------------FIELSGGSWWQQPGDI-TECVMDGKFISTLGWPTLGNTL--------------- +MAQKSVLMLC----GEFME--------AYETIVPLYILQAFGVNVHCVSPARKTGDKCVMAAHDLL-GL-EIYTELVVDHL--TL--NANFEDVIPDHYDAIIIPGGRF-TELLSADEKCVSLVARFAELKKLIFTSCHSQLFLAAA-------GLTGGMKCTAFGSMKP-------------------LIELSGGAWWQQPGDI-TDCVKDGSFMSTMGWPTLAHSL--------------- +GGKRSVLLLC----GDYME--------DYEAMVPFQALLAFGVSVDAACPGKKSGDVCPTAVHQST-GH-QTYSETRGHNF--AL--NATFDEIDPSKYDGLVIPGGRA-PEYLAMNDSVIDLVRKFSNSGKTIASICHGQLILAAA-------DVVKGRKCTAYPPVKP-------------------VLIAAGASWIEPE-TM-AACVVDGNIITGATYEGHPEFI--------------- +SHQKTVFLLC----GDYME--------DYEAMVPFQALLAYGVAVDAACPGKKAGDYCRTAIHESS-GH-QTYSESRGHNF--TL--NSTFDDIDFGKYDGLVIPGGRA-PEYLAMNESVLDCVRKFADAGKPIASVCHGQLILAAA-------GLVKGRKCTAYPPVRP-------------------VLIAAGAHWVEPE-TM-ASCVADGNLITGATYEGHPEFI--------------- +KGERRVLLLC----GDYME--------DYEAMVPFQALQAYGVAVDAVCPGKKAGDICRTAVHDSS-GH-QTYSESRGHNF--VL--NATFDDIEFSKYDGLVIPGGRA-PEYLAMDPKVLQLVIKFSDSKKPIASICHGQLILAAA-------GLVKGQKCTGFPAVGP-------------------VLVAAGAHWVEPG-TL-ASCVVDGNLITAPTYEEHPEFI--------------- +MAPKKVLLLC----GDYME--------DYEAMVPFQALRAYGVSVDAACPGKKAGDSCRTAVHQGI-GH-QTYAESRGHNF--AL--NASFDEVNINEYDGLVIPGGRA-PEYLAMDEKVLDLVRKFSDAKKPIASVCHGQLILAAA-------GVVQNRKCTAYPAVKP-------------------VLVAAGAKWEEAD-TM-DKCTVDGNLVTAVAYDAHPKFI--------------- +TVQKSALLLC----GDYME--------AYETMVPLYILQSFGVSVHCVSPNRTAGDRCVMSAHDFL-GL-ELYTELVVDQL--TL--NANFDDVTPENYDVIIIPGGRF-TEILSADEKCVDLVARFAESKKLIFTSCHSQVMLLAA-------GVAGGVKCTAFESMKP-------------------LIELSGGEWWQQPGEI-TDCVKDGNVVSMVGWPTLGHGI--------------- +APDKKLLFLC----GDYME--------DYEVMVPFQALKSYGIECDTVCPGKKAGDSCRTAIHDFE-GD-QTYSEKRGHNF--VL--NSDFDGVSHDKYDGLVIPGGRA-PEYLALNEKVISLVKDFASSKKLIASICHGQQILTAA-------DVIKGKKCTAYPAVGP-------------------QCKAAGADFVEAN-PI-DLAVTDGNLVTAAAWPGHPKFV--------------- +MAPKKVLLLC----GDYME--------DYEAMVPFQALQAYGVSVDAICPGKKPGDSCRTAVHQGI-GH-QTYAESRGHNF--TL--NASFDEVNINEYDGLVIPGGRA-PEYLAMDEKVIDLVRKFSVAKKPIASVCHGQLILAAA-------GVVQNRKCTAYPTVKP-------------------VLVAAGAKWEEAD-TM-DKCTVDGNLVTAVAYDAHPEFI--------------- +MAARRVLLLC----GDYME--------DYEAMVPFQALQAYGVSVHAACPGKKAGDACPTAVHKPV-GH-QTYAESKGHNF--AL--NASFDEVDAAGYDGLVIPGGRA-PEYLAMDEKVLDLVRKFSDAKKPIASVCHGQLILAAA-------GVVRDRTCTAYPAVKP-------------------VLVAAGAKWVEAD-TM-KKCVVDGNLVTAAAYDGHPEFI--------------- +KPQRRVLLLC----GDYME--------DYEVMVPFQALLAYGVSVDAVCPGKKAGDACRTAVHQMG-AH-QTYSESRGHNF--TL--NATFAEIEFNAYDGLVIPGGRA-PEYLAMDQSVVDLVSKFSHAGKPIASICHGQLILAAA-------NVVKGRKCTAFAPVGP-------------------VLIAAGAHWVEPE-NM-SLCITDGNLVTGVAYTGHPEFI--------------- +MSERRVLLIC----GDYAE--------DSEVMVPFQALQAYGVSVDAVCPGKKAGDFCRTAIHQSS-VH-QTYSQSRGHNF--TL--NASFDEIDHTQYHGLILPGGRA-PEYLAVNESVVDLVRNFVNSGKPVASICHGPLILAAA-------GSVNGRKCTGYRAVRP-------------------ALIAAGALWVEPE-TL-AACVVDGNIITGCTYKGHPEFI--------------- +KGERRVLLLC----GDYME--------DYEAMVPFQALQAYGVAVDAVCPGKKAGDLCRTGILYGA-GH-QTYTESRGHNF--AL--NATFDDIEFSKYDALVIPGGRA-PEYLAMDQKVVNLVTKFSDSKKPIAAICHGQLILAAA-------GLVKGRKCTAYRLVGP-------------------VLVSAGAHWVEPE-TL-ASCVVDGDLITGTTFKGHPEYI--------------- +SKSKSVLLLC----GDFME--------DYEAMVPFQALMAYGVSVDAVCPGKKAGDICRTAIHELL-GH-QTYSESRGHNF--AL--NATFDEIDFDKYDGLVIPGGRA-PEYLAINSSVQSLVRKFSESGKPIASVCHGQLILAAA-------GLVRGRKCTAYSPVGP-------------------VLAAAGASWIEPE-SL-AACVIDGNLITAATYESHPQYI--------------- +MSEKRVVLLC----GDYAE--------DYEVMVPFQALLAYGISVDAVCPGKKAGETCRTAIHQLS-GH-QTYTEIRGHNF--TL--NASFEDIDHTKYDGLVIAGGRA-PEYLAMDAFVLNMVRNFVNSGKPVASICHGQLILAAA-------GAVGGLKCTGFPAVGP-------------------TLIAAGALWIEPD-TL-AACVVDGNIITAATYIGHPEFI--------------- +--ERKILILLSEW-----------GYWGEELVGPLETFDKVGYQVSFCTPTGRRPNIAVSMDPLYIDPPLKKEIDDPSTNQGKRLDTPINLRQESLDEFDALLIVGGSGPIVDLANNQRVHDLILGFYGQGKPVAAECYGVTCLAFARNIENKQSIIWGKQVTGHCIEYDYKDGFLDFNMGPPPYPLEYILRDAGGAYIGNFG-HPTSVIVDYPFITGRSTPDSYLTGQKLVEVLD------- +--RRRVLVLLSEF-----------GYWGEELVGPVEVFDAAGYRADFLTPTGKRPVITVSMNPEYTDPPLAREWDDPATVQGRRLETPLNLSEREIENYDALLIVGGSGPICDLANNHRVHDLILGFHRADKPIAAECYGVACLAFARELEDRKSLIWGKHVTGHCKEYDYKDGFYDINMGPPPYPLEYILRDAGGGFHGNVG-RETSVIVDYPFITGRSTPDSYLTGQKLVEVLD------- +--KRRILVVVSEW-----------GYWGEELVGPIGEFDRVGYAVDFCTPTGKRPNIPVSMDPDFFDPPLAREFDDPSTENGKRLQHPISLADVGIERYDAVLIVGGSGPVVDLVNNQRVHDVILSFLAAGKPVGAECYGVACLAFARDMNIRKSIIWGKHVTGHCLEYDYKDAFLDFNMGPPPYPLEFILRDAGGGYHGNFG-HPTSVLVDWPFVTGRSTPDSILTGQKLIEMLD------- +--PRRILCVLSEW-----------GYWGEELIGPVEVFDAAGYQVDFCTPTGRRPNIAVSQDPAYIDPPLAKLWDDPSTEEGRRLENPLNLSARALAVYDALLLVGGSGPVVDMVNNQRVHDLVLLFYRSGRAIGAECYGVACLAFARDIQDRVSILRGKRVTGHCLEYDYKDGFLDFNMGPPPYPLEYILRDAAGAYVGNFG-HETSVIVDYPFVTGRSTPDSRLTGEKLIEVLD------- +--TKPILVVCTDEGHLEMANGFNTGNHPVEMFVPMLHFKDVGFTFDIATARGKPVVLEMWAYPNK-DESVKALYEE----VKAMLEKPKKIEDINLDGYAAVFIPGGHGCMVNLPACQPLGKLLNQAHARALPTVTLCHGPCALLATCAETSGQCTYAGYKTMCFTDKTDAFTPSIGYLPGPMPWKVEECLVAKGVEVLNKS--ETGAVTQDRELITGDSPDAAHNLGVLAAP---------- +--MARILMVVSAADSLTMKTQHPTGFWAEELVTAHRLLSEAGHTVNIATPNGKRPTDAISLDPENAGGQAAAYLR----EIEPELSSPLVLSEVTAGHYNAIVLPGGHGPMADLASDAALGRLLVEADREELIIAPFCHGPAALLSAVD-DGGEFAFAGRHLTVFTDEEELG----------------------------------------------------------------------- +MAEKRILMLV----GDFVE--------DYEAMVPFQMLGMVGHTVHAVCPGKKAGETVKTAVHDF--EGDQTYTEKPGHNFM--LN--CDFDSVDVAHYDALVVPGGRA-PEYIRLNARVIEIVRQFDKARKPIAAVCHGQQVLVTA-------GVLQGHTCTAYPAVKP-------------------DVEAAGATWCEVNDT-ASNACVSGHVVTAPAWPAHPEWMRKF------------ +MAAKKILMLV----GDFVE--------DYEVMVPFQILTMVGHDVHAVCPDKQAGDQVRTAVHDF--EGDQTYSEKPGHLFS--LN--ASFADIDVADYDALVIPGGRA-PEYLRLNPQVIDMVRHFSQQAKPIASICHGQQILVAA-------GVLQGVTCTAYPSLQP-------------------DIELAGGSWHEVVET-FANAHTHGMLVTAPAWPAQPEWMRQF------------ +-MAPSALVLIT------------DGNEEMEAVISIDILRRAGVDVTVAGLNG-P----NTVECS------------R----HVKIVPDTGLSAVKDKTFDAILLPGGMGGAEAFSKSSTVHELLSQYYSQQKVVAIICASPIVLKAA-------QVAKGRSVTAHPSVKD-------------------QLVQ-DYNYKE------ERVVVDGNLITSRGPGTAFEFALAVVKKLQ------- +-MTTKVLVAIA------------DGVEEIEFVTPVDIMRRAG-DVLIASVGDN-L--N--VVGA------------N----GIKLCADVLL-DL-DKGFNAIVCPGGLGCSKALAESNLFKEHLHHTK--GGIIAAICASPALLEP-H------GLL--EHAVCYP-MKN-------------------QLS---PHPEQ------PHVAVDA-VITSQAPGTAIEFGLHLVAALC------- +-ASKRALVILA------------KGTEEMEMIIPVDVTGS-----------------------------------------------DAS-LDA-ERLYDA-VVPGGNLSAQNLPESAAMKEILKEQ-ENQKLIDAICAGPTAL-AH-------DIGFENKVTTYPLAKD-------------------KMVG-HHTYSE------NRVEKDGLILTSWGLGTNFKFALVIVAALS------- +-QKSALILLPP------------EDAEEIEVIVTGDVLVRGG-QVLYAGSS---T---EPVKCA------------K----GARIVPDVAL-DVKNKTFDIIIIPGG-PGCSKLAECPVIGELLKTQV--GGLIGAICAGPT-LLA-H------GIV---RVTCHY-VKD-------------------KMT--GYKYLD------DNVVISD-VITSKGPGTAFEFALKIVETLE------- +----MIAVLVD------------DGFEELELGAVVSVLSRGG-DWDLV--GVE-E--R--AEGM------------G----GMEVGVDSTV-D-EGDDYEGVVVLGGSAPTT-LIGY----DLVRSV-SDGGMVVGLSSGAL-LAE-A------GVL---KATTYPG-EA-------------------EL-VNGAEPVP------KGVVRDGNVVTSRGPAFAIDACLEVVRELC------- +---MKIAALVA------------DGFEEIELISVIDLLRRAE-KTEIWGLN---Q--L-QFSGG------------H----NIKLIADKIF-PGS-TEIDGLFLPGGKQGVENLVNSPPVLNLIENLYNKQKWLVAICAAPFV-ET-A------GVL---TVTIYP-WES-------------------KLI--AARVNQ-------PVVIDGKIVTSRGVGTALELGLTLCRLWC------- +---MKVCIFIA------------KGFEELESISVVDILRRGN-DVHMVSITD--S---LEVFGA------------H----DIKIICDKLF-DI-FADYEMAIFPGGVGGVEEIRKFKPIYELIEYMYSNNKYLSAICAAPV-LGD-A------GLL---KFTCYE-FEQ-------------------FVK-G-IY--K------EKVVINNKIITSNCAGSIFDFGFKLLSLLR------- +-MTQKIAILLT------------KGFEESEALVPNDLFRRAG-HTDLISIDNT-----EIVSSS------------H----NVKVVADQLL-Q-DLNSYDLVMLPGGQVDLEKYAA---LADTYRQFAQQQKWVAAICAAPT-LAK-V------GLLK-KNAVCYPS-RA-------------------DLI--EVNYRH------LTTVIDAPFITGRGPGAAFDFGLAIVAQLL------- +-IMSKIAVLCN------------DGVEEIECLTVVDFCRRAG-EVLTVSVTG--K---RQIMGA------------H----QICFHADEVY-DM-FEEFDGIVYPGGP-GTGVLGEKPGVKELAQKFLNSGKMLAAICAAPG-ISE-T------GIL---HATGYP-CNP-------------------QGG---AIW-E------DTAVTDGNLITGKGPGAAAEFSIAIIRYLE------- +--MGRICVFFA------------PGYEEIEALAVVDLLRRAG-DTDMVSITKE-----REITSS------------H----GVTVHMDKVFEEVDFEETDMIVLPGGMPGTKNLEAFLPLMEKLDEFY--KKYIGAICAAPSILGH-R------GMLK-RRACSFPEFES-------------------HLE--GAQVEQ------SPAVISDFIITGRGMGCAVDFGLAIVEKFQ------- +--MAKVYEFLA------------DGFEEVEAMAPVDILRRGG-DIKTVSVTGS-----EWATSS------------H----GVTMKADLVFTRPDFADADMILLPGGLPGATNLNEHEGVRATLLAQA--GRRIGAICAAPMVLGS-L------GLLE-KKATCSPGFER-------------------YMT--GADYTA------ELFQEDGMILTGEGPAATLPYAYHILGYFV------- +-NVNKSYLFLA------------PGFEEIEALTTVDVLRRAG-SVETVSITDT-----TAVTGA------------H----NITVKADTTLSQAEIDRPDWLICPGGMPGASNLVACDKLASLLRDHA--SGRIAAICAAPAVLAQ-L------GILD-REATCYPGFEQ-------------------MAP--KAIMVD------RSVVVDGNIITANGPAAAMPFALAIVKATL------- +-VMKKASVFMA------------DGMEETECLTIVDLLRRGG-AVTTFSVMP--D---KTVTGS------------H----GVRIEADALF-ADA-ADAELLFLPGGGDGVKHLYAHQDLCRLLVNFPAESKYLGAVCAGPS-LGR-L------GLL---RATCYP-FEE-------------------QLL-AVC---G------EGITVDGAVVTGIGLGFCVDLGLTLVALLC------- +-MAARVLIPLA------------KGFEEIEAISVVDVLRRTGCEVILAAVDEKSQE-TLIVESQ------------G----GVKVVADLKITEI---NLDAVVLPGGWEGTQNLIASSALHTILSELNAKGKICAAICAAPLALFKH-------NILINQNFTCYPSIEE-------------------MIES---NYKA------DNIVQDSNIITSRGPATALEFAFYLASLLG------- +---MKTYIFLA------------NGFEILETFSPVDVLKRCG-EVITVSTE-K-D---LFVSSS------------Q----NNIVKADIML-E-Y-KDADLVVIPGGYPGYINLRENKDVVDIVKYF-ENDKYVASICGGPT-FSH-N------KIA---KITAHS-VRK-------------------EIE---HIYVD------APTHVDGKIITGVGAGLALNFAFKIAEQFF------- +-MTNKVAVLMA------------EGYEEGETLTIVDILRRAG-NCDTFYFG---D--KL-VKGM------------H----GIFVEADKPF-EE--KQYDMIVLPGGRPGGQNLKENPDVIDMVQYFNQNNKYIGAMCSGTV-LSD-A------KVI---QVTGYV-Y---------------------AEK--GGIFDE-------VVVADQNLVTSQGPATPYPFAYKIAEIFG------- +--MKKILLFIY------------DSFAEFEIVLFTTALNQEE-QLVTF--STK-PA-GETVTGV------------S----SMSYVPTLTI-D-DVNEFEALVIPGGTTHPL-LTH-----AIIRAF-DQHKTIAAICGGPA-LGA-A------GIL---TFTASLTEYN-------------------DV-HWD-NKLE------QMLVVDRQVITATGSNY-VQFAEEVLRRIG------- +-VMKKVLVFLA------------EGFETIEALSVVDVCNRAKVTCHACSLTEN-----RTVNSA------------H----GTMVLCDKLISDN---TYDAIILPGGMPGATNLRDNERVQSLIKKYNKENKIVAAICAAPIALAKA-------GVIEGKKVTSYPGFKE-------------------ELG--NVNYVE------ETVVVDGNIITSRGPATALVFGLEILKKLG------- +--MAKVYEFLA------------TGFEEMEAIVPVDVFRRSG-EISMVSVTG--S---KVVKSA------------R----GVGIEADVLL-EI-FDDVDMLLLPGGVLGANNLKEHKEVRKILLKQFESGRFLGAVCAAPL-FAS-I------GIL---KATIFP-MED-------------------SLI-GAEP--R------TLVQVDGNVITGAGPVAVLPYTYELLSHLL------- +-MSVKALVLLA------------DGFETVEACFPIDILVRCG-QVSTASVSTA-S--KKQARSA------------H----NVVIQTDGMV-DMEDQSYDVIVLPGGMPGATTLGKSATVKKMLQNQA--KRWIAAICAAPAELAA-N------NLL--K-GVCYPAFQK-------------------AMG---DSLV------------HGRLITGDGPASAALFGFTIAKHLG------- +-TQSRAFLFLA------------DGFEITEAMAPADILVRGG-ELNTISIS-D-S---HIVTSA------------Q----RISVNAEFTL-EYI-RTEDIMIFPGGMPGSTNLAACAPLVNRMQRHYAEGGTVAAICAAPA-VLS-L------LPL-G-KMTCYE-FEP-------------------YLT--GVTVQR------QGVVADAGIISASGAGHAVDFGLKILELIS------- +--MPSALVCVV------------DGFEPIECITVVDVLRRGG-SVTLAGTE---K----MQAGA------------H----GVTVCMDALV-EVS-TLYDAIILPGG-PGWKEMQRNDTIKALTEKHSQHGKWVMSICAAPSALAF-W------GLL---RATCYP-LKD-------------------GMV--GAQFDE-------PVVVDGNFLTSQGPATALAFAIKALEVLV------- +--------------------------------------MFGQ-AVTV-------AGDVSCVKCS------------R----NVKICTDAMFT--QDKSYDIVILPGGLNGSKAFTSVAEVGRLLQK--QENKLIAAICAA--PALKTH------NIGK-KRITSYPS-KN-------------------ELS---YEYID------DKPVVIDDLMLIRGPATAFDFSLAIVEILT------- +--MKRILVPLA------------EGFEEAEFIGIADVLKRASLEVITASLTDH-----LLVKGA------------H----GIKIQAETSLSSI--DSLDAIALPGGFDGMNNLKNSPIIIKTIQELHAKKKLIAAICASPIVLNHA-------GVLRG-DFTCYPGCEA-------------------EIP---TRKN--------AIVVSQNIITSAGPGTAILFGLEIVRYLL------- +-NMPKVIILAV------------PGVEPMEVVCPVDLLRRAG-DVKIAAAC---TN-EIQVEAS------------F----GIKIVADVMF-SIN-ETFDLVIAPGGMSGPDNLTNNQDTIEFIKRHDMAGKLVAAICAASGYLAKAC------GIM---KGCRYP-LDT-------------------PIE--GGELTD-------IVTRDGNVITSRGPGTSLQFGIALVEALF------- +--MPKVLVLAA------------TGFEPMELVNPTDLLRRAGADVKVAAVGTQ-G---LQVDAA------------H----GVKIVADVKFDAV--ETFDLIIAPGGMPGTKNLAANHDVVEFIKRHDKAGKLVGAICAAPGFLAQAC------GIMKGRKGCGYPGCDN-------------------AIA---GGELT------TAVTRDGNVITSRGPGTSQQFGLALIEALI------- +-MTTKILVIGF------------PETEETELIITVDILRRAE-NVTIANLND--E---EYFTCV------------Q----KTTIKADKLF-DVENETFDAVIIPGG-PGSYKVANNDRLVTFLKKHD--GKLLAAICGAPV-FAQ-N------KIG--GKMTSYP-DKE-------------------KIE--GFVYDE------LDVVVSN-IVTSRAPGTAFEFALKLVEILV------- +-MAKEVAVIFA------------DGCEEVEGLTVVDVLRRLE-PTKMVGL-TD-----RQVMGA------------H----QIALTCDAVV-D-DLLTADVVAFPGGRGGAERLRDHEALKSIMVQRQ-DGKWNAAMCAAPI-FAR-Y------GLFK-ADFTCFPGFDQ-------------------VILPS-ARFHE------D-TVVQRHLITSRGPATAMAFAYEIAEQLG------- +-FMPKVAVVFA------------NGCEEIEGLSVVDVLRRLN-ETDMVGL-TS-----KTITGA------------H----NILITCEKIV-N-SLLDYDLVAFPGGSKGAENLRDSQELKDLMIKRH-EHKWNAAMCAAPI-LAR-Y------GLLK-TDYTCYPGFDE-------------------QTKPT-GRFYK------N-TVTTQKVITSRGPTTAWAYAYEIAEQLG------- +-MAKKIAVVCA------------NGCEEIEALTPVDVLRRLG-EVDIVGL-SG-----QEITGS------------H----QIKFKADRLL-A-SLLDYDMVVLPGGLPGADYLRDSELLGDLLNQRH-AGKWNAAMCAGPK-LAK-N------GLLD-TDYTAYPEIDQ-------------------EVAKE-ARFHD------DLVIVKQKVITSRGPATALAYAYQIAQVLG------- +-MPKKVLVPVA------------DGSEDIELSCITDILRRAD-QVTVSTVMDH-Q--A--VQLA------------R----GLKLTPDSNI-DESAAAYDGVFLAGGLPGADHFAKSSHLKKIMVEMH--GKWYGAICASPAVLGP-M------GLL--KTATCYP-MKE-------------------RLP--TVRWSA------DPVVRCG-CLTSMGPGTAIAFALAIVAALS------- +--MVKVLVPVA------------DGTEDIELSCMTDIMRRAD-HVTVTSVMET-P--T--VRLS------------R----GLVLTADSLI-NESAEAYDGVFLPGGLPGADYLGQNEHLKKILGDIR--GKWYGAICASPVVFLP-L------GAL--KTITCYP-LKD-------------------KVP--HVKWSS------DPVVRCG-CLTSMGPGTAIAFGLSIVAALA------- +-MSKRVLVPVA------------DGSEDIEFTTICDVLDRAG-KVTVASIMET-K--N--VTLA------------H----GLKLEADTLV-DEKASDYEAAFLAGGYGGSKNFGASEDLKKFLHELR--NKTYGAICAAPVLLAP-L------GML--TKATCYP-MEN-------------------MFP--HVTAST------DVVVKSG-CLTSRGPGTTLFFGLAIAALLV------- +--MVNVCLFVA------------DGNDEIEFSAPWGVFTRAQ-PIDSVYVG-E-NP-EKLVTMS------------R----GVQLYAKRSL-EFFASHYDVIIIPGGMKGAKTLSTD----KLVTSYWKSGKVIGMICAGTL-A-K-T------TGL----ITGHPS-RK-------------------DL-ESGFRYVP------QPVVVENNLITSMGPGTALIWALKLMEQVA------- +--MVKVCLFVT------------GGSDEIETASCYGVFTRAK-PIDTVYVCEE-NK-ERLVNML------------C----GIRLYADRSL-EFFMKEYDVVIIPGGWGGSLEIPGT----EIVRGMYKPGKWVAMICAGSM-V-M-T------SGL---ELTSHAC-ID-------------------VL-NAGYNWVD------EPVVVSNNLITAQGPGTSMLFALKIAEQVL------- +-RQKAAVILIA------------DGTEEMEFTITYDTLIRAG-DVVSVFVPEDSSASPPIAKGS------------R----GINIMPDSYLD--SPDKYNLLVVPGGAKGADTISKN-IVKELVKEYYT-GKLLGFICNG--STALTA------GLPR-QPLTSHPG-KS-------------------VLE---FQYSE------DPVVVSGNLITSRGPGTSFPFALTLVEKLL------- +---MKVFVLLN------------NTFEEIEALTVVDYLRRAS-DVTTVSMH---E--KLLVKGG------------H----NIEVSADITF-NLR-DMIDVLYIPGGLPAAREISENKEVIELVQYLKENNKIIAAMCAGPLILET-S------QIA---VITSFP-VKD-------------------E-L--IKEYED-------VVVKSGNIITSRGPATAVFLALKLIEEIK------- +--MDRYILILT------------DTFEEVEALTQVDYLKRAD-KVDMISIT-G-K---LQVPSN------------R----GITVLADDLI-N-L-KEYAGIIIPGGLPAAFDIRDDKRVLDIIKTFDEEHKLISAICAGPS-LAK-A------GVL---NAVIYP-MEN-------------------ELL--ANVKE-------DAICIDDNIITARGAGLAGELAYTLIRKIK------- +-MTKRVLLLLA------------DGFEPLEAAGFTDVLGWANIELVSA--GLR-S----PLKAT------------F----GFSVIPQALV-E-DLDSFDAVAVPGGFEGAG-FYED----DIIRRF-DKQQPVASVCVASL-LGA-A------GVL---RATIYHQRRA-------------------QL-HYGAKFVD------EAVVVDGMLITSTGPGTAIEVAFELLTVLT------- +--MKRVLMLLA------------NGVEPMEMAAFTDVLGWADIELVNA--GLR-R----KIITT------------F----SLTLNPGFLL-D-DVSSFDALALPGGFEPAG-FYEE----ETIRHF-DAGKPVASVCVSSV-LGV-A------GVL---NATTYHQRKN-------------------QL-ETGALFVD------RPVVVHDNIITSSGPGTATEVAFLLLEKLT------- +-GRRTAVVLLS------------EGAEELETVAVVDILRRAEIEVTLASTTGNV----EPIKCS------------R----GVVIKPDDIFDAIKVNLFDVVVLPGGLKGAEFLANSTEVGKFLKLHEENGKLIAAICAAPIALKSH-------RIAEKHQITSHPVVAN-------------------EFLA-MYTYSE------KM-VVHDNLVTSRGPGTAIAFALRLVSILI------- +-MSKKACIIIV------------VGVEEMEVLTLLNILRRAG-EVIVAGLWG--D---ISVKCK------------N----KLVILPDKSL-SIKDIDFDIIILPGGIPATKAMQDSELLAEVLRKQE--KRYIATMGTSTI-LEH-H------AIM--KNVTSDP-YKT-------------------IMC--GYNYNE------KSNVVDG-LITSAGLGTTMEFALRIACIFT------- +-VAPTALIPVA------------NGSEEIETVSLQDVLVRGGVQVTLAAVGGD-E--HNVVKMS------------R----GLHIKADVAIGEC--LDFDLIVLPGGMPGAAHLRDCPDLIDMLRHQKRMGKWYGAICAAPAVLHHH-------ELLPTGPVTSYPSFEG-------------------KMP--A-EY-S------SRVVVTSNCVTSRGPATAMEMGVTLVQLLC------- +--RPAVLIPVA------------DGTEEIELAALSAVLAEGG-RLTSVKLDPD-PP-DRFVKLM------------H----GLEIQTDTLL---VNKDFEAIILVGGEGTST-LAAS----EFVK-YQHSGRLFGASGTAPI-VLL-H------HGI---PLTCAPS-AK-------------------Q---AGELYRS------DAVVLSGKCITSQGPASAILFGLEILKVLR------- +---MKILIFAY------------QQADDIELICSADFLRQNG-IVVIY--AQT-T----PITLS------------H----GTVLIPDTTF---PP-ICDAILLPGGQGFKQ-LIKN----QLFQQY-LQSKYIFTISSA-S-LVQ-W------KIW---PVCTYPG-------------------------VQGAVYQN------QQVVVGGKYICGRGIGGIIEFLEQIHKKFT------- +--MPSALLYMF------------EGCEEIETYGTADILRRAG-KVTLFATT-K-T---V--TGN------------Q----GMIMTADS-----V-VDADAIIIPGGMGFANLE-ADMKAKALVESYVQKGKLVCAMCAAPQ-LTK-W------GVW---KVCGYP-CEA-------------------P----GNTFVD------DRVVVGDKHVCAKGPGVALEFGVAIATKLG------- +-MTFRALITLA------------EGIDDLQAVTLIDVLRRAK-EVVVASIESR-----RMLTCA------------R----GTRLTADAMLVDVLAQPFDLVVLPGGAVGAQRLAAHQPLLQLVQDQSAAGRLFSGIAESPALLQA-F------GVLR-RRMTCLPA-SH-------------------QL--LGCTFVD------QPVVIDGNCITAQGSSAALAFALVLVERLC------- +-MLKTALVPVA------------EGTEELEAVTIIDVLRRAGIEVTVASANHG-D--NLHIRGA------------N----GTHIVADKMLDHC--TSYDLIAVPGGIPGAEHLAAHPALDILLRQQAHEGKLYSAICAAPALLASK-------GLLADKTATCHPKYQQ-------------------SLQ--K-KVDG------ARVVVDGNCVTSQGPGTAIDFALQLVEQLC------- +--MTCALIVYA------------NGSEDMEVTAITDILNRGG-KVTKAALNDD-G--GLKVTLA------------H----GTTVVCDKNL-DC-ADDYAVIAIPGGLVGAENCRDSTTLIAKLQEQK--DGYIAAICAAPGFLAT-H------GLV---RATGYP-CAD-------------------NIE----NYVD------KGVVV--KLITGQGPAFCMEFALAILEELK------- +-FDKKYAVIIA------------DGSEEIEITVPTDILRRSG-TCELISVN-C-----LTVIGS------------H----GIKITADKLI-EVY-SAYDGVIVPGGMDGAKAIAACKQATDFIYGLYNRQKLVAAICAAPA-VLS-E------IPQ-C-TITCYP-KDL-------------------ISR--YCRYRK------SEVVSSANLITGNGPLAVFKFSMVICRHEH------- +--MFRIAVIVA------------NKSEDIEVITPVDIWRRAG-FVRII--SVE-KK-K-NLILN------------R----GTRIVCDDVI-N-NLSKYNGIYLPGGEGYKN-FND---ISFLKHNA-NKKITYMAACAATQ-YGC-L------EML---KATCYPG-EA-------------------SF---KKSYVN------KPVVADKNFITANGPSAMIEFALTVVKKCL------- +--MANIAIFLA------------TGFEDTEMVATNDVLNRSK-MIDLVSIN-D-D---LKVEGA------------H----GLNVIANKLI-D-F-NDYDCLVLPGGGLGVENLKKCELLLNKIKEFNDSEKAIAAICAAPQ-LGT-L------GIL---EVTHYP-CVE-------------------GLE--AIRKPH------VAAITDKNIITGSSIGAALQFGLQIVDYFT------- +---MKGIILLA------------NHFEDTEALVTIDLLRRAG-TVDMVSIE-K-S---VDLVTQ------------Y----NLKIKAEFTV-Q-L-NDYSFLIIPGGKAVILTHLSSKITEDVVNHFAKKNQLIATICAAPS-VGK-L------GYL---EFTCFP-FEE-------------------YV---GIYLPN------KNVVVSNNYITAKAAGATFDFAKEIIKYLT------- +---MMLLMVFA------------DGFEDTEAIATIDVLKRGN-TVDAVSLM-D-T---LSVKTK------------C----GFCLVVDKLF-D-I-AEYDGIIIPGGPGSFKLMPSMDNLTNAIHYFAKNNKLVAIICAAPH-VGR-L------GYF---DFTVHP-FEN-------------------QV---GNYRSD------LGVCKAKNFITAKSMYYSLEFGYAIYEYFN------- +-KNNRILIIAA------------DGYEDLEFTASFDILQRWG-NVDVAYLLQE-GK-K-YVTSA------------C----GLNVMVKETL-SIKLDNYDHLMIPGGDGNVW-RLDK--TSKIIEHF-TKNKKIGAICAAPV-LAK-R------GYL---YAICYPA-KY-------------------QSILSCKADQD------CSVVIDNNIMTGLDFKTAVKFADKLVTFFN------- +-PKSLLLFIPQ------------TDFSEEEYLAVTSALKRER-NYFIA--SDA-T--G-ICVGS------------S----GLKVKNDIQL-N-HPANFEGLILVGGSGARN-YKGN----KIVQEF-RLKKPIGAICSAPL-LAK-A------GVL---FAVCYPS-KP-------------------EL-SFGVKYKD------APVVEDGRIITARDPNAAVEFAESFAGLIK------- +-RQIRIAAIVA------------TGVDDLELIIPTDLWRRAR-IVDYI--SIE-KK-N-SVTLA------------Q----GTSIKCGLTI-K-NLMQYNAIYLPGGLGSKR-FGDD--LSKFNEKD-TTPRYILAINESPI-LKN-L------GLL---KVVASKE-KD-------------------AI---GSNFDS------KNVLLSDNIITARATGHAIDFAIETVKILA------- +-SNIRIAIMCS------------IESNDMDIVIPYDIWTRAG-IVETV--SNE-KK-K-SIFLQ------------S----GTKITCSEEI-K-NLDKFNALYIPGGKGCQR-LLTD--NKIVKFAG-EGKKWLFTAGAAST-LAE-L------GVL---KITTAPG-EE-------------------KL---GKNYSD------NNIVVDKNFVSFKSPFHAFEFALLIVEKLL------- +-EMNMIYILLG------------NGFEEAEALVPLDLLRRAG-QVKLVGLD-G-----LEVTGS------------H----GVTVKADITM-EAP-EDMEMLVLPGGLGGVEAIQKNLFALALIQKAYDRGCWLCAICAAPT-LAR-A------GCL---KAVCYP-MED-------------------EMG---VVQ-G------AQVVTDGRIITGEAAGSAFEFGLRLVEAAC------- +-TDSAVAVLIA------------PGLEEVEALAPVDILYRAG-RADLVSVTD--S---LTVSSS------------H----QIVLTCDRLL-EVL-ADYALVFLPGGIPGTPNLKAVPAVRQEAARRMNEDLPVAAVCAAPS-LAE-M------ELL---RATSNP-FMD-------------------VLA-HGARV-E------DAVVADGALLTSRGMGTAVELGLEMVRRLL------- +-TDASVGVLIA------------PGLEEVEALAVVDCLYRAG-RADLIAVPASDSQRSLNVTSS------------H----GITLVCDLHL-DAL-SEYTVLFLPGGMPGTVNLEENTKIREEIARRIAFGEPVAAICAAPS-LAH-A------GFL---NATANP-FMK-------------------DLE-GGAHA-T------DSVVVDGNVFTSRGMGTAIQLALSLVKHLL------- +-MAIQVAMIIF------------DGFEEIECVTTLDLLRRAN-RVDLI--SID-ND-K-KSIKG------------S----HYELVTEYKF-DFTLSNYNGIIIPGGPGIVQ-QLTNNNNNNNNNIE-NNNRFLAAICAAPQ-FGK-C------GLL---KVTHFPG-NQ-------------------FM--DSIELLD------QTIVVDGNIITASSAGVTIPFALKIVEFLK------- +-NKVKLAIFIF------------DGFEEIEAVTTIDLLRRAN-LVDIVSVENK-K---KLIKGS------------H----YIEISADISW-E-A-ELYNGIIIPGGP-GINKLLLNEQVVEMVKKFGANNKTIAAICAAPQ-LGK-S------GLL---KVTHFP-CKQ-------------------FMD--AFEEID------KAAIADGNIITGASAGVSQTFALKIVEHLK------- +---MKCAIFMA------------DGFETCEGLITVDLLRRAG-TIDMISMNE--T---LTVTTS------------H----QVKIQADKLF-EF-QNVYDVMIFPGGKLGTENLENNQKLIDLYEAHFKAGKLSCAICAAPS-LGH-R------GLL---KYTCYP-FDE-------------------SSF-G-EY--Q------VLAVKDGNLITGRGMGATIDFALKIIETLC------- +--MTKILVLLA------------DGFEEIEAIAAIDLFRRVDIEVVTAAVNNQ-----LAVRGA------------H----DIIVEADCLMNDV---VYDCLYLPGGGKGAETLRDNAVVQQIIKKHYSSKKLISAICAAPIALEKA-------GILEGHTVTSFPAVKQ-------------------DIT--TPLYSD------NNVVISDAIITSRAAGTTIELALAVVERLC------- +--MHALFLIAK------------ENFRDEELFEPKKILETAG-KTTIT--SIE-S--G-LAKGS------------R----GGTTTIDLPI-D-HIEDYDILIAIGGPGSPA-LGDY----DLIRK-ASLGKPLAAICIAPY-LAK-A------GVI---KATSFHGAIS-------------------EF-RQGVTRIQ------QPVLRDGNLITADGPMSAKDFGQEIIKLLS------- +--MSRFAVLLA------------EGFEEIEFCTITDILRRAD-EVKIV------GLKNGLTGGS------------R----GIRIMPDMYI-DLT-TDYEVLVLPGGNPGFINMGKDQRVLELIRTAHTENKYLAAICAGPAV-SR-A------GVI---EVAIYP-VKH-------------------LLK---CTADL-------RVKVEGKLITGRSPQAAMDFALTLMDMFA------- +--MKIAILIAF------------KDFRDEELFTPQRVFTSVG-EFKVF--STE-V--G-IAQGA------------D----GGTAIVHSYI-N-QVSDFDAIVFIGGPGAIR-ELDN----KIIHE-AVKEKVLGAICVAPV-LAK-S------KIL---KATVWTDTRE-------------------VL-ENGAIYEN------QPVVQDGKIITAVGASAAETFAQKIVQALK------- +--MSRVVVPLV------------EGFEEVEALTIVDILRRAGVDVVTAAVAE------SPVRSS------------H----DVPVGADTTVAAV---EVEMVVLPGGPGT-PRLAESPDLKALVQRLRDADREVAAICAAPSVLAEF-------GVLDGKRATSFPAVKE-------------------KLT---VDYQE------DTVVRDGKVTTSRGPGTAMDFALELVGILE------- +-MAETVAVMLG------------DGFEPVEVVAPVDVLRRGG-EVTLVSVMG--R---KEVTSA------------Q----DIKMVADALV-DV-LDLFTMVVVPGGSVGVENLGKCDKLAESLRDRMKANKLVGSICAGPT-LAN-L------DLL---KAVCYP-CET-------------------NF--AGVYQ-N------VDVCIDKNLITATGPATALPFGRALLEALK------- +-MVPSVLVILA------------NGFEEIEAITPIDMLRRSG-NVTVAGLDNL-T-----IIGS------------H----KLEVTCDALL-DC-KQTYDCVVCPGGSLGSKNLASSFLVLEKC-IQT--KGVVASICAATAVLGK-T------GLL--T-VTGYP-TEK-------------------ECP--GLVFSS------EKVVTDR-LVTAQGAGCAMEFSLAIIAKLF------- +--MKKVALTLV------------SDFEIVEAMAPLDMLRRAG-YVDVISVEN--K---DYVKSA------------I----NIEIKVDKKL-DV-LSTYDLVILPGGP-GTKNYYDHQDLLDKVKANYNNKKMVSAICAGPS-LAN-L------GIL---NAISFP-FQH-------------------VLV-NNAKL-N------EQVVVSDNVITGRAAAASIDFGLKLVEMLE------- +---MKCAILMD------------NGFEELEAMGPIALLRRGN-DVDVVSVKG------HEVTGR------------F----GVTYSPAIPM-EYDFDSIDCLIIPG-GPHYKKIENNESVKTVIEKVVKDEKVVAAICAAPT-LGK-M------GLL---NYTCFK-LNE-------------------NF---GGTYHY------EYTVTDGNLITGISAAAAIEFAFAIMEKLC------- +-TTPTALVIVF------------DGIEEIEALTPVDILRRAE-KVTVASVN---G--LPTVTGR------------N----QITFAADTSI-RVE-DSFDLVILPGG-PGVLELLENQAVSHILVAQDKAQKELAAICAAPKVLAN-H------GIL---KATSHS-VRD-------------------A----PR--SD------DPVVIDSHITTSQGLGTAVDFSLTLVKKLK------- +-MIKRALVILA------------PGFEEIEAVVPIDLLRRAKIEVVVAGILPG------VITGS------------R----KIRIIPDYDLGDV--EHFDCIILPGGAEGAENLKKDIRIKELLERQILKGGWVAAICAAPGCI-NF-------GLFLSNKFTCHPSIKA-------------------EIP---SRLEE------NSVVVDGNLITGRAAGSAIEFSFEIIRQLV------- +---MEASIFIA------------NGVEECEALLVVDLLRRGG-EIQTVAVN-DATGKARTIVSS------------H----QVPLICDVHL-SYP-SDEKVLVIPGGKLGVDNLKASAKLSQIL---RSHQENLAAVCAGPT-LGA-L------GLL---KATVYP-FQD-------------------GLG---ADY-D------TGLIHDGRIITARALGASIDFALEIIALLR------- +---------MG------------EGFEEIEAITVYDVVKRIG-KAQFVSIG---D--DVTVRGS------------N----GAEMRCDKCI-DFL-DDVDALVLPGGLPGASNLGKSTEVKAIIGEAVQNKLYVAAICAAPLFIDK-M------EEF---NVCLYP-LAG-------------------ELE---TNYEA-------DVLVDGRLITGKGPSKAMKFALSILENVY------- +-LSRFIAILFA------------DGCEEIEGLTVVDLARRAG-GIDSISVK-E-E---TEIRGS------------H----GIIFQADTCM-RAG-TAFAFGLA--I-VAYVRGEEAARRLG-QETLYD------------------------------------------------------------------------------------------------------------------ +---MKVAVLLE------------TGFEELEAMGPIALLRRGG-DVDMIGVNNE-----EQVTGR------------F----GITYSSVFPM-TYDFSNVDCLVLPG-GPHYQKLEKNEEVLKLVHE-FAENKVLAAICASPT-LGH-E------GIL---KYTCFK-MDE-------------------DF---GGEYQY------AYAITDGNIITGVSAAASIEFAFAILEKLC------- +---MKGLLVLY------------DRFEDCEALVTRALLNRVA-PLTTATLN-P-Q---LEVMSS------------S----GLCVKADANL-T-P-LEYDFLVIPGGPYVAQIIEKETFLLKLIQKFVDANKVIGAICAAPM-LGK-L------DLL---PFTCFP-CNH-------------------F----GTYLPD------QKAVISDKFVTSRSPITVFDFVFALVEVLK------- +---MKGLLILS------------DFCEDLEALGTRALLKRAQ-EIDTVTYN-E-T---KEITTA------------F----GLDVKVDYHM-E-L-DDYGFLVIPGGKYVAMIIESDTRIKSLAKIFETEDKMIAAICAGPR-LGE-M------GIL---QYTIYK-LQE-------------------ES---GIYKEE------LKAVTDGKIITGRGAGATIEFALEIIAFVK------- +---MVVGIILA------------NGFEDIEAIIPIDILRRGNVNIQIISTN---D--SNVVISS------------K----GVSFLADDIISNC---CFDLIILPGGMPGATNLFNSKELDLILKDMNSKGKFIAAICASPVVLAAK-------GLLGFNKFTCYPGLEK-------------------NVLG---EFVD------ENVVRSNNFITSKGVGTSFEFAFTLLEMVK------- +--MSKVALFII------------DGFEEAEAVVTADLLRRAD-GLKIVSLSD--K---KEVLGK------------H----NITVTADVLF-E--NDIFDMLVIPGGTIKYIE---HKGLLELVKKQHAAKRNLAAICAAPA-FGT-A------GIL---KATIYT-MRV-------------------YLG-GAVY--E------EPVVTDRHITTSRGPGTSMAFGVRLIEILK------- +--MKKVFVLLA------------NGFELIEAMTPVDVLRRCG-EVTTVSTEE--D---LWVESS------------N----SVIIKADKYW-E--FEEGDILILPGGYPGYVRLRENRLVVSQVEKYLTTGKYVAAICGAPS-FSE-H------KLA---KLTGHS-IQE-------------------DLK-NHIY--G------ETTTVDRNLITGIGAGHSLDFSFEIAALLF------- +-MTKKVYIFVA------------NGTEETEAVGTYDTLKRGG-DAYFVSINPT-----KEFTSS------------H----GLQLTAHYTIEEVKDEVVDAVALPGGMPGATNLYECELLREIITRHL--GRHIAAMCASPLVFGR-M------GLLE-KKATAYPGFEE-------------------ELK--GAKYKE------KPAVVDGQIITGRGPGYVFNFGAAIVGELV------- +-MTKKVALFIE------------NGSEELEFIAPLDIMRRAN-EVDLISAN---N--EDFITSA------------H----NVKIMADKKI-EII-LDYDAIVIPGGMPGSTLLRDNKKIIEFYQTMYNSGKLVAAICAAPIVLSA-A------GIT---EVTSYP-FDK-------------------E-I--K-NYSD------KAVVIDKNVITAQGPAVAILFGYEIVNYLL------- +--MKDLLVFLA------------DGFEEVEALSVVDILRRGGLSVDTCSIKDS-----KKVTSS------------H----QVTVLADVHIDDI---NYKACYIPGGQPGATNLQNDRRIIQIVEMFKEQGKLVAAICAGPQVLDTA-------GVLTDEKFTCYPGVEE-------------------RLK--TKKRL-------DPVVVDDNIITAMGPAMAPFLGYELLKVLS------- +---MKAMILLS------------KNYEETEAVAVIDILRRAE-DIDVVATEG--D---LDTVGD------------H----NITIRADYLL-DIKGADYDILITPGGVGGTNALRENDKVIDLLKEQY-DSSYIASICASPR-LDK-A------GIS--IRGTIFP-LSD-------------------QVT--EYVADE------IVVNDDH-VITSQGPATAYYFALEIVRQLK------- +--MNKFLVLVA------------NGNETIEIFTVIDYLRRIG-KLDIASTE-E-S---KELKTS------------Q----DVSFKADISF-D-E-EDYMGVYIPGGTKGAYAMRDNEKVLDLLRRFNDAGKIIGAICAGPV-LNE-A------GIL---KATSFP-MKD-------------------EMD--GEYVDN------EIVVTDGNITTGRGAAVTNYLALRLAYIIG------- +--MKTSFLFLA------------EGFDEIEAVAVWDILRRAG-EVKSVSMT-G-E---KTVVGA------------H----NVAVVSDVLY-S-S-DDVEGYILPGGIEGTKNLFMNDDFKMNLLNHYNQGRYVGAIGEAPS-LGE-L------DML---NATAQP-YMN-------------------FLQ--ATYTG-------LPVEIQDNVITGRGAGDSFKFAIGIVSMLK------- +-MSKNAALLLA------------TGFEEAEAFITLDILSRLG-KVTTVACQTQ-----REIVSY------------H----GAVIKADTLIEEADAHLFDALIMPGGPEGSKNLAASSAVTALIQRHDDAGMLIAPICSAAARLGGN-------NLLK--RYTCSGEGLE--------------------VK-DGE-YVM------EDVVEDGNLLSGRGLGVAFDFALTLAQRLT------- +-MTKKVAVLLS------------EGFEEAEAVIVIDVLRRME-EVELLSCQDR-----LELRSY------------H----QIRMFADALLERMD-QLYDAVVIPGGPQATAAMAENELVVEFIRRHDRAAKLICPLCSAAARLATN-------KLLQ--RYVCSGDHQE--------------------IE-DGT-YVA------ERVVEDGNLISGQGLGAAFDFAFTVAYRLT------- +-IGKRVAILLA------------QGFEEAEAIIVIDILRRLD-TVEKLACQEG-----LELLSY------------H----DIRIFADALLSNAN-DLYDAVVIPGGPEGTVNLAANPQVAEFIRRHDAAGKLVCPLCSAAARLGGN-------GLLN--RYVCSGDYQQ--------------------VA-DGI-YVD------QKVVEDGNLLSGKGLGVAFDFAFSLASRLT------- +-MASKVLVPLC------------PGFEEMEAIILIDVLRRGK-EVVSVSKT---K---EPIIAS------------R----NTIHLADKTF-EVKADDFDAMILPGGLNGTKNLLAEGEVHSLLHSFH--QKHIAAICAAPA-LRK-L------KII--DPYTAFP-TED-------------------LVK--GGKYTG------NRIESHN-VHTSIGPGSAFEFALYILELLE------- +-GKKTALVAVA------------SGSEDVEYITVVDVLRRAG-HVTTASVEKS-----EQVCLS------------K----N-VVLADTTI-KVRNNIYDVLVIPGGMKGSNTISECSEFIDMLKEQKANNRLYAAICAAPETLDR-H------SLID-VEAVAYPS-ER-------------------NF-----KHIG------KRVCVSKNCITSVGPGSAVEFGLKIVEHLL------- +--MVKALVLLS------------QGCEETEAVTTIDLLTRAG-DVTYASIT---E--EREIKCS------------R----GVVILTQKTFSQVKELSFDVVILPGGLIGAENFRDSVDVIEKLKRTHAEGNIVAAICASPALLQYH-------NLFP-AEMTGYPS-KQ-------------------IFK----NWK-------ERVFY--KVLTSQGPATSIDFALKIIAVLV------- +-QYPRVLVPIT------------DGTEDIEAVTVIDILRRTQ-DLVVATVGK--N----QITAA------------R----QTKIVGDKSI-DVLSENIFFVMLPR-GPGASKLYESKELKKLLDAQV--GGLLAAICAAPAVLAQ-H------GFL--VECTCYP-DKF-------------------SEI-DAKLLEK------ERVVVRTVVITSQGPATALDFSLTIVEVLW------- +--MSAAWIACA------------KGSEELEVVGVANVLRRAG-DTDIVSMED--E---LEVSCA------------R----RVTLKADRLW-QPEAERPDILILPGGLEGTERLAQHGALVASLQARQ--GRWLAAMDTAPVLLKT-H------GLL--AQVTGHP-FHD-------------------RLP--QGLKAD------ALTVT--RLITSQGPGTAMLFALSIIEVLA------- +-ATPSVLLCLA------------HGNDAIEITTFLSLLPRAG-QVTVASVEGD-S--TLALRSA------------E----GLTFQADLPL-QAVDNAHDVLLLLGGRESSQTYVESDLVIESIAQFT--QRYVAAMSHVVPGIDK-V------DRF--ANVTCLT-QRA-------------------LLQ--HTQWQE------RRVVL--HLLSGQGPLCATDMALKIIELLK------- +----------------------------IEITTFLSLLPRAG-QVTVASVEGD-S--TLALRSA------------E----GLTFQADLPLCQAVDNAHEILLLLGGRESSQTYVESDLVIESIAQFTASQRYVAAMSHVVPGIDKV-------DRFR-ANVTCLTQ-RA-------------------LLQ---TQWQ-------RRVVL--HLLSGQGPLCATDMALKIIELLK------- +-SRKIAMVVAH------------SGFGDEEFLIPKGIFESVG-RVIAA--SND-H--G-EAVGK------------Y----GAVVQVDTIA-H-HPHDYLAIVLVGGPGVAV-FYND----RILQDF-LQRKVVAAICSAPV-LAN-A------GLV---KVTVFAD-KD-------------------SV-AGGAYYTG------RTVEVDGQIVTANGPGAAKEFAEEILKAID------- +-QTPKIAICIA------------PGSEEMEVINTADILIRAG-QVTMASAAED-G--SLSVKGS------------R----GITLTADCPMVEIVDEPFDCVVLPGGLPGAEYLRDSTLVVEFVKQHKYDGKLVAAICAAPVVLEHH-------MLYP-ALMTAHPG-VE-------------------QIP---NRRRG------RRVMH--NLLTSQAPGTSQEFALEIITLLM------- +-HSKLAMIAVS------------DGSDELETLILYDVLKRAN-RVIACS---T-KD-GKIVHTS------------H----GMKLVTTSPV---VDYNIDLIALPGGETLDG-LRDC----KLLK-KQEKGKWIAALSNAPA-ILM-P------HLL---KATCHPS-AR-------------------D---MTGYFVD------QDFAVTKTCITSQGQGTAMRCALKLVEILC------- +-LDRGALVLVG------------NGVEELDVVSFVTALKEAN-EVVTA--SIE-G--NRTIRGK------------Q----SLTFRADTIL-D-KPLDFLGVVIPGGNKNYT-LTMS----VLVRC-QDRKGICCSLGSGVI-LKN-S------GIL---QYTAPPD-RE-------------------QL-D---LEED------VAVKADENVVTSQGGGTALDAAMTLVELYQ------- +-MSVRVYLFVA------------HGFEEVETITPLDYLRRAG-ALTLVGVG-A-----EQVVSP------------R----GLRVSCDCSL-ALA-CAADAVLLPGGLENCHTLAACAAVRDFVMRVHLRGGLVAALCAAPA-VLS-A------WNL-G-RYTCYP-MDP-------------------AVF--HDDRER------ARVVRDGNLLTACAAGAAEEFSFAVIEALC------- +-MAKRVLEFIA------------EGFEDVEAVTPADYLRRAGIEVTLVAVGAN-----TVVKSS------------R----GLTLMTDTTLAEL--SGWDGLVIPGGMPGASNIAGSVTAVTFLKDMHHAGKVVAAICASPAVLAPL-------GILAGKRFTCFPGMEK-------------------QVS----AIWK------ERVVVDGNLITSRSAGTAGEWAYEIIKKLM------- +-EGKATFVMLG------------TGFDEIEAIAPVDVMRRAG-EVYTVSMT-E-N---RLVRGA------------T----GNNIVADMTV-D-P-SQIDWLVFPGADKSEAAVNLDKELQNIVTAH-ENGGKIAAICAAPALLGP-L------GII---PATGYP-LKD-------------------EFE--GGTYSD------DNVVITDRLITSKGPGTTLEFALAVVRIAK------- +-GRYRALIPLA------------NGNEDIEVIAMIDVLRRAD-DVVIASVSNE-D--T--VTLM------------K----GSRLVVDEPL-NVVHQQWDLIAMAGGIPGAMNLAASKLLRDRLRLQH--KGMIGAICLAPALLKP-A------GVL--KIVTGNPLK----------------------TP--EQSWPA------DYFISLGKIVLSQTPGTAIEYAIAMVKMLC------- +--SRKILVIVSEH-----------GYWSEELIGPVSKFDERGYEIVFATPTGKRAHLPPSLDANYVDPPLVTTEERREFEQSNRLDSPLDLDKIDIADYDAILIVGGSGPIADLANNERVHALILAFKKAGKVVAAECYGVACLAFARDWGDRKSIIWGKHVTGHCKEYDYKDGLGDFNMGPPPYPLEYILRDAGGAYHGNGHPL--SVIVDYPFVTGRSTPDSYLTGQKIVEVL-------- +---KSLLVILTNSSKLSHPTSHVTGFDIKEVAYIYMKLTKFKAPITFATPRGGEAPDPSSRKEGEKDEIVREFL--RDSSLQSMFRSTTSLDEIRPEDYFWVLIPGKHGAMMDLSENSTLRRILSTIYNDQGYIATIGHGVSALLCCQTGEFGPNFLKNRSLTGPTNEEESMLKMD----KLVPYLIEDRLRECGAKFEKE-SPFKPFVVVDERLVTGQNCNSVNQWIEHI------------ +--KWKVLLIATQE-RYLKMSFFSTGNHAVEMLLPMLHMDAAGFDIDIATLSGEPVKFEMWAFPKE-DKAVQAIYDK----YRDKIRNPLNLQDVADTPYLAVFIPGGHGVLNGVPFSATVGDVLRWAHAHERFFVTLCHGPASMLAADVPAGSRYIYEGYKVDVFPDSLDEGANIIGYIPGKMAWLVGERLRAVGVEPINS--QITGEVHRDRLLLTGDSPLASNNLGKLAAKT--------- +----------------------ADGVERVELEQPREALDRAGAQTEVLSIHDGEIKRKNDLDE------AG------------TFTVDRLVTDASAGDYDALLLPGGTVNPDQLRVDKDAVSFIRDFVESGKPVAAICHGPWTLIEA-------GVVGGRTLTSFPSIRT-------------------DLRNAGAEVID------QDVVVDGNLITSRSPEDLPAFCDTIVAK--------- +----------------------ADGVERVELEQPREALDRAGARTEVLSVGEGEIQRDNDLDP------AG------------TFSVDGLVAEASVADYDALVLPGGTVNPDKLRVEQDAVAFVRDFVESGKPVAAICHGPWTLIEA-------GVVTGRTLTSFPSIRT-------------------DLRNAGADVVD------QDVVVDKNLITSRSPDDLSAFCDALVSQ--------- +----------------------KPTVVRMSRAASWTRPERAGAQTEVLSIHDGEIQRENDLDA------AG------------TFTVDGLVADASVTHYDALLLPGGTVNPDHLRVDPDAVSFVREVVESGKPVAAICHGPWTLIEA-------GVVEGRTLTSFPSIRT-------------------DLRNAGADVVD------QDVVVDGNLITSRSPDHLPVFCDTIVTQ--------- +---SKVLILLSSVE---------PGTSPKHFVQVYSV-CSTVFPTHISTANGLPPIWSKNTPHTHMDDATSKWI----ADKKNILSNPLSLEDLDPENYSGLVVPDADGFYFEP-CCQKIHSFMEYFLKFKKPICMIGSGTAVLFSTEPKTGDMWIFRKFALTAPSNVSLIQSD---QYL-T-NRSIEDFISDMYGRYSTGK-SESLHVVIDDHIVTAQANTSTLIAIQ-------------- +---PACLLVASGVA---------EGVSAQSFLHCFTL-ASAAFNLQVATPGGKAMDFV-------LTESNARWV----QDFRLAYASPAKLESIDGARYHALLIPSCPGALADLANSGSLARILQHFRSESKPICAIGHGVAALCCATS-EDRSWVFHGYSLTGPSVYELI--P---GFA-RLPLVVEDFVKDSGAGFSGKP-GMPPNS---------------------------------- +---PACLLVASGAA---------EGVSAQSFLHCFTM-ASTAFNLQVATPGVREGLDVPSHQQKGKNPGRHFWV----SGHRFTSRGPQRCVPLS------------------------------------EPICAVGHGVAALCCATN-EDRSWVFHGYSLTGPSVCELIRAP---GFA-RLPLVVEDFVKDSGACFSASE-PDAVHVVLDRHLVTGQNASSTVPAVQ-------------- +---PTCLIVASAAA---------QGVSAQSFHQAFCL-CSSVFNLQTATPGGKPIDFV-------VDETTARWI----QDFSQSFATPAKLESIDGARYQALLIPDCPGALTDLAHSGSLARILAHFTSQQKAVCAIGQGVSGLCCAIV-EGQKWIFTGYSLTGPSVFELVRSP---DFA-NLPLIVEDFVKDSGGSYTGEC-GGR------------------------------------- +---PRCLQPASGHP---------WGVSAQSFLHCFTL-ASAAFSLQVATPGGKPMDFV-------VNESNARWV----QDFRLAYASPAKLESID------------------------------------EPICAVGHGVAALCCATS-EDRSWVFQGYSVTGPSGAQGACRR---GPS--SPIEWVAARRSWGGSGGAPP-GXALHVVLDRHLVTGQNAGSTVPAVQ-------------- +---PVQI--QRKCR---------SGVELHAILGGD---PTSTPTSNVATSQGKLIDFA-------VNESNMRWI----QDFRMSYANPAKLESID------------------------------------EPICAVGHGVAALCCATN-EDKSWVFQGYSLTGPSVYELIRQP---SFA-SLSIIVEDFVKDSGATFSASK-PDAVHVVLDRHLVTGQNENSTVVAVQ-------------- +---PSCLVVCSSHK---------EGVCAQSFIHAFTL-TNSAFTLAIATPQGIPIDFV-------VDDTNRRWI----SDFRGSYASPMKLESVDPSRFAALLIPSSPGALYDLASHDTMMHIVRHFMDERKPVCTVGYGAAALTAGKL-TNIGWCCEGYSLTGPSVYEMVQLK---NFS-TIPIVFEDYAKDNLASYTAST-PDSVHVVIDRNLITGQNSQSTLTAVQ-------------- +---PSCLVVCSSHK---------EGVCAQSFIHAFTL-TNSAFTLAIATPQGIPIDFV-------VHETNRKWI----TDFRTSYASPLKLESVDPSRFAALLIPSSPGAQFDLASHDTMMHVIRHFMNEKKPICAVGFGTVALAAGKL-NNTGWCCEGYSLTGPSVYEMIQLK---NFM-TLPLVFEDFAKDNFASYTASI-ADGVHVVIDRHLITGQNSQSTLTAVQ-------------- +---GSCLLVLSASS---------PGVTAQSFVQAYTL-AATNFTVQLATPEGKQSEFI-------QDEHNRRWF----NEFRSSASTPISLESVDANRYAALLIPPAPGAVNDLAHNKDLADILNYFIQEKKPICAIGMGVAGLCPATLSNNSYWNFQDYSMTGPSVLELARNA---DFA-NLPIVPEDFIKDNGASYSSSE-CDAIHIIVDRHLVTGQNVQSTLIAVQ-------------- +---PTCLIVLSSAA---------QGVSAQSLYHSYTI-CSTAFNLQIATPGGKPMDFV-------LDENNLRWI----QDFRMPCSNPAKLESIDGARYNAILIPNCPGALVDLATSGYLAKILQHFYTEKKLICAVGHGVAALCCATN-EDKSWSFQGYSVTGMSVFELVRRK---DFA-SLPIIVEDFVKDSGATFSASE-PDAVHVVVDRHLITGQNDQSTLTAVQ-------------- +---PACLFALSSAA---------EGVSAQSFVQSYTL-CSSAFTLHIATPGGKLPEFV-------QDEASLRWL----QDFCTPQSTPLRLESVDGARYNALFLPSSLGALSDLAHSGYLAQILQHFVAEQKPICAVGHGVAGLCCALK-EDRGWAFRGYSLTGPSVFELVRKP---GFA-NLPVIVEDFCKESGATYSAAE-VDAVHVVIDRHVITGQNEQSTVAAAQ-------------- +------------------------GVSAQSFIPALTL-THSAFNVQIATPKGLQVEYT-------VDESSRKWL----NDFRSPFSVPGKLENVDADRYCALLIPNSLGALHDLAHDDQLAKLLNSFINAKKPICAIGHGVAGLLSAKTESSKSWSFKGYSVTAPSVVELCRTP---EFS-GLPIILEDSIKDNGATYSASE-PDCVHVVIDRHLITAQNDQSTLPAVQ-------------- +---PSVLLLFFGGC---------SSVSAQSFLHSFTL-ASGAFNLQVATPGGKLIDFV-------VNESNMRWI----QDFRMSYANPAKLESIDGARYHALLIPNCPGAMTDLANSGYLAKILQHFSNENEPICAVGHGVAALCCATN-EDKSWVFQDYSLTGPSLYELIRQP---NFA-SLSIIVEDFVKDSGATFSASK-PDAVHIVLDRHLVTGQNENSTVLAVQ-------------- +---HNCLIVLSGCK---------EGNSAQSFIQSFTL-LHTNFTVQIATPGGKPLEFV-------QDDQSRRWL----NEFRMSIAIPISLQTIDPHRYSCLLIPHSPGAAFDLSDDKDLAQILQNFIQEKKPICAIGMGVAALFSAC-D-EDSWSFSKYSLTSISVFELARNP---DFE-SIPIIPEDVVKDRLATYSCSE-PDEVYVVVDRHLITGQNEQSTITAVQ-------------- +---LSCLIVLSGSK---------DGNSAPSFIQTFTL-LHSTFTVQIATPGGRPLEFV-------QDDQSRRWL----NDFRMVFAIPIGLHTVDPNRYSCLILPHSPGAVHDLCENKDLGQILRHFIQEKKPICAIGMGVAGLFSAM-EDSDVWSFRRCTLTAVSVFELARSP---DFA-NLPVIPEDVIKDRGALYSSSD-PDEVHVVVDRHLVTGQNEQSTLTAVQ-------------- +---LHCLMVLSSAV---------EGVSAQSFIQAYTL-ASSNFSIQLASPHGKNVEYV-------QDDNNRRWF----NEFRSASSNPIAFETVDSARYSALLIPSSPGAVHDLASNTELSQIVNHFIREKKPICAIGSGVAALCCVMSPDD------------------------------------------------SE-MDAVHVIIDRHLITGQNAHSTLMAVQ-------------- +---GSCLIVLSSAV---------EGVSAASFMQACTL-VNQSFAIQLASPSGRQVEYV-------QDDSNRRWF----NEFRSSNSTPIALDTVDVNRYSAVLIPPCPGAIHDLASNSDLGQIIAHFIKEKKPICAIGQGVAGLCSARKEDGKSWWLEDFCLTAPSLFEIGYLP---EFP-AMPLILEDFIKDYGGKYTATD-PDEMHVVIDRNVITGQNVHSTVIAIQ-------------- +---PQCLCVLSAAQ---------QGVSAHSFIHSFTL-THSVFQVQLATPMGQPIEFV-------IDENTKRWI----SEFRTSFATPTKLELVDAADYSVLLIPNSPGAVYDLSTHRELGNILNSFIADKKPICAIGFGVAALCSAMSMDGRTWMLREYSLTAPPVREMVSRS---DFA-MMPIILEDFLREHGASYTANA-GVGVHVVVDKHLITGQNDQSTLTTVQ-------------- +---PACLLVASSAA---------ECVSAPSFLHCFTL-ASAAFNLQVATPGGKAMDFV-------VDESNARWV----QDFRLSYASPAKLESIDGARYHALLIPSCPGALADLASSGSLARILQHFHSESTWSCFLRSAISGHCCSVNLCPVVWRWGGALMDGPSVYELVRAP---GFA-HLPLIVEDFVKDAGASFSASE-PDAVHVVLDRHLVTGQNTSSTVPAVQ-------------- +---PTCLLVASAAS---------AGVSADSFNQSFTL-ASAAFNLQVATPGGKSIDFT-------VNEANMRWI----QDFRMPYANPAKLESTDGARYHALLIPDCPGAMTDLANSGYLARILQHFSSENKPICAVGHGVAALCCATN-EDKSWVFQEYSLTGPSVYELIRRP---NFA-GLPIIVEDFAKDSGATFSASK-PEAIHVVVDRHLVTGQNDNSTIAAVQ-------------- +---SSCLIVCSGSI---------SGVSAQSFIHSFTL-IHSAFNVSIVTPNGNPIEFT-------IDDNSSRWL----KEFKSPFSIPAKLEEVDASSFSAILIPSGLGCLYDLATSSALSSCLVSFMDDNKPICAVGHGVAGLCSAKM--NNEWLFKEYSLTAPSLLELSNLD---NFS-SFPIILEDFIKDNDACYSKSK-PNCTHVIIDRCLITGQNDSSTLSAVQ-------------- +---PSCLMVGSAVA---------EGVSAQSFLHSFTL-ASSAFNLQVATPGGKALDFV-------ISETDSRWF----QDFQLPYSNPARLESIDGSRYHALLIPHCPGALTDLANSGYLARILQHFTAEKKPICAIGHGVTALCCATN-QDKSWVFQNYSLTGPSVYELVRRP---EYA-SLPLILEDYAKDSGATFSASE-PDAIHVVLDRHLITGQNDNSTMPAVQ-------------- +---LAFQTLVGLCF---------SGVSAQSFLHCFTL-TSSAFNLQVATPGGKPIDFV-------VNESNMRWV----QDFRMSYASPAKLESIDGARYHALLIPNCPGAMTDLANSGYLAKILQHFSTENKPICAVGHGVAALCCATN-EDKSWVFQGYSLTGPSVYELVRQP---NFA-SLSIIVEDFVKDSGATFSASS-PDAVHVVLDRHLVTGQXENSTLPAVQ-------------- +------------------------GVSAQSFLHCFTL-GSVAFNLQVATPGGKAMDFV-------VNESNTRWI----QDFRLSYASPAKLESIDGARYHAVLIPNCPGAPVDLANSGYLARILQHFSAESKPICAVGHGVAALCCATK-EDKSWVFQDYSMTGPSVYELIRQP---GFA-SLPIILEDFAKDSGATFSASR-PDAVHVVLDRHLVTGQNDNSTVAAVQ-------------- +---PSCLIVASASA---------GGVSAQSFHHCFTL-CSSAFNLQVATPGGKPMDFV-------VDENTMRWI----QDFRMPYANPAKLESIDGARYHALLVPGCPGAMTDLANSGYLAKILHHFSTEKKPICAVGHGVAALCCVTN-EDKSWMFQGYSLTGPSIFELVRRA---DFA-SLPIIVEDFIKDSGATFSASE-PDAVHIVLDRHLITGQNDQSTLIAVQ-------------- +---HPGISDLFSCL---------TGVSAHSFLHCFTM-GSAAFNLQVATPGGKAMDFV-------VNESNMRWI----QDFRMAYASPAKLESIDGARYHALLIPSCPGALTDLANSGYLARILEHFSTEQKPICAVGHGVAALCCAT--EDKAWVFQNYSLTGPPVCELVRQP---GFG-SLPIIMEDFVKDAGACFSASQ-PDAVHVVLDRHLVTGQNEASTVLAVQ-------------- +---PTCLIVASSAA---------AGVSAQSFLHSFTL-ASSAFNLQVATPGGKPIDFV-------VNDSNLRWI----QDFRMSYANPAKLESIDGARYHALLIPNCPGAVTDLANSGYLARILQHFSTENKPICAVGHGVAALCCATN-EDKSWVFHGYSLTGPSVYELVRQA---NFS-SLSIIVEDFVKDSGATFSASK-PDAIHIVLDRHLVTGQNENSTIAAVH-------------- +---CL--LVASAAA---------AGVSAQSFLQCFTL-SSSAFNLQVATPGGKSIDFV-------VNESNMRWI----QDFRMSYANPAKLESIDGARYHALLIPNCPGATTDLANSGYLAKILQHFCTENKPICAVGHGVAALCCATS-EDKTWVFQGYSMTGPSVYELIRQP---NFA-SLPIIVEDFVKDSGATFSASQ-PDSVHVVLDRHLVTGQNENSTLPAVQ-------------- +---PTCLIVASASP---------QGVSAKSFLQCFSL-CSTAFNLQTATPGGKAIDFV-------VDESTARWV----QDFNVSYATPAKLESIDGARYQALLIPDCPGAPNDLAHSGSMHRILTQFISQQKPVCAVGQGVSALCCA-T-EGQKWIFSDYSLTGPSVFELVRQP---DFA-NLPLIVEDFVKDGGGSYTASQ-EDAVHVVVDRHVITGQNQQSTSLAVN-------------- +---PTCLIVTSASP---------QGVSAKSFLQCFSL-CSSTFNLQIATPGGKPIDFV-------VDDTTARWV----QDFNLSYATPAKLESID------------------------------------ELVCAVGQGVSALCCSTE--RQKWIFSGYSLTGPSVFELVREP---DFA-NLPMIVEDFVKDSGGSYTGSQ-EDAVHVVIDRHLITGQNTQSTSLAVN-------------- +---PTCLIVASATP---------QGVSARSFQQCFSL-CSPVFNLQTATPGGKTIDFI-------IDENSARWV----QDFSVPYATPAKLESIDGARYQALLIPDCPGALKDLAHSGSLARILTHFSSQKKPVCAVGQGVSALCCA-T-EEQKWIFSGYSLTGPSVFELVRSP---DFA-NLPLIVEDFVKDNGGSYTASQ-EDALHVVLDRHLVTGQNVQSTTAAVN-------------- +---PTCLIVASAAS---------AGVSARSFQQCFNL-CNPVFNLQTATPGGKSIDFT-------VDDSTGRWV----QEFSIPYANPAKLESIDGARYQALLIPDCPGAMNDLAHSGSLARILSHFISQQKPVCAVGQGVAALCCA-T-EDQKWIFSRYSMTGPSVFELVRSS---EFA-NLPLIVEDFIKDNGGSYTASI-EDAVHVVLDRHLITGQNIQSTTAAVN-------------- +---PTCLIVASGAA---------QGVSAQSFLQSFTL-CSAAFNVQTATPGGKPIDFV-------VDEGSLRWV----QEFSVPYASPAKLESIDGARYNALLIPDCPGALGDLAHSGSLARILAHFVSQQKPVCAIGHGVSALCCA-T-EEQRWIFSGYSMTGPSVFELVRHS---NFA-NLPLIVEDFVKDSGGSYTASI-EDAIHVVLDRHLVTGQNQQSTSAAVN-------------- +---PTCLIVTSAAP---------EGVSAQSFLQAFSL-CSSAFNVQTATPGGKAIDFV-------VDETSARWV----QDFSVPYANPAKLESIDGARYHALLIPDCPGALTDLAHSGSLARILTHFXVPAEPVCAVGQGVAALCCA-T-EGQAWIFRGYSLTGPSVCELVRRL---DFA-SLPLIVEDFAKDCGAAYAASQ-EDAVHIVLDRHLITGQNSQSTAAAVN-------------- +---PTCLIVASASP---------QGVSAASFHQSFSL-VASVFNLQTATPGGKPMDFV-------VDESTARWV----QDFNLPYATPAKLESVDGARYQVLLLPDCPGALNDLAHSGSLHRILTHFIAHQKPVCAVGQGVSALCCA-T-EGQRWIFDGYSLTGPSVFELVRRP---DFA-NLPLVVEDFVKDSGGSYTASQ-EDAVHVVIDRHLITGQNMQSTLLAVN-------------- +---PTCLIVASASP---------QGVSAKSFQQCFCL-CSSVFNLQTATQGGKPIDFS-------VDESTSRWV----QDFNMTCATPAKLESIDGARYQALLIPDCPGALNDLAHSGSMHRILTHFISHQKPICAVGQGVSALCCV-T-EGQKWIFGGYSFTGPSVFELVRQP---DFA-NLPLVVEDFVKDNGGSYTASQ-EDAVHVVVDRHLITGQNLQSTSLAVN-------------- +---PACLLV-SGAA---------EGVSAQSFLHCFTL-ASAAFNLQVATPGGKTMDFV-------VNESNARWV----QDFRLAYASPAKLESIDGARYHALLIPSCPGALSDLASSGSLARILQHFRSESKPICAVGHGVAALCCATN-EDRSWVFQGYSVTGVSALRGVPGC---QFS-VLPACTVFFVSRNGLCLAASE-PDAIHVVLDRHLVTGQNASSTVAAMQ-------------- +---TQDSALSKALG---------GGVSAQSFLHCFTL-ASATFNLQVATPGGKAMDFV-------VTESNARWV----QDFRLAYASPAKLESIDGARYHALLIPSCPGALADLANSGSLARILQHFRSESKPICAIGHGVAALCCATS-EDRSWVFHGYSLTGPSVYELI--P---GFA-RLPLVVEDFVKDSGAGFSASE-PDAVHVVLDRHLVTGQNANSTVPAVQ-------------- +---GTEGGRDRFLP---------SGVSAHSFLHCFTL-GSAAFNLQVATPGGKAIDFV-------MNESNTRWI----QDFRVAYASPAKLESIDGARYHALLIPSCPGALTDLANSGYLARILEHFSAEQKPFCPVGHGVPPFCCATK-EDNFWVFRDYTLTGPSVGELIREP---GFG-GLPVIVEDFVRDAGACFSASQ-PDAAHVVLDRHLVTGQNDASTVLAVQ-------------- +---PACLLVASGAA---------EGVSAQSFLHCFTL-ASAAFNLQVATPGGKTLDFV-------VNESNARWV----QDFRLAYASPAKLESIDGARYHALLIPSCPGALADLASSGSLARILQHFCAESKPICAVGHGVAALCCATN-EDRSWVFQGYSVTGPSVYELV--P---GFA-HLPLIVEDFAKDAGACFSASQ-PDAVHVVLDRHLVTGQNAGSTVPAVQ-------------- +---KNILVILSNSD---------KSIDYKIVQQVYDE-FSSEFNVLASSPIGGIVQFL-------NDEAQES-----------DSKKTIPFDLVDPQNFEALVIPSMYGGMIDLVNNERLGYLVIEMYKSKKIVTCIEYGVSGLLSAKN-IGNEWIFDGLSLTGPTLHQEDKPP---DFT-VPSFYMETVIRSNGGEYSCSD-PSAIHVIVDSNIVTAQNQSSSCLALK-------------- +-------MPEIETE---------GGISGSALLICHQL-KEAGFACAISTVAGERPALV-------VDLSDEKIH----PDLRSLVDDPLAIIDIRASDYCALLIPHHLGAAQDLLNCDVLGDVLAAFLKQHKPICTIGYGTYGLCARQS-SSNGWQFAGRLVTGVSVSDECRHP---HFA-KLPIVLQDFVEESGGTFVECP-NDQVCVIVDRNLVTGPNEASTGVCIH-------------- +---QRALLLTTASA---------LGISAHSFIHSYTL-ASSLFAVTIATPGGGPLHFP-------TDANSRRWL----DDFLAPAAVPVAVESLDLTLFAALLIPGGAGTITDLPHNAAVAHLAMAFDRDKKLICAVGLGVSVLCASALNKGADWQFAGRCMTAPSNVELARTT---LLA-EQPLLLEDFLRDNGACYSAAK-SDSVHVVIDNNLITAQNDASTLSAVQ-------------- +-MSRRILVVLSEY-----------GYWGEELIGPLETFDKAGYHVTFATPTGKRPVLPPSMDPDYIDPPLEMAAKVKAVEASDRLDHPLDLSSQIADRYDALLIVGGSGPIVDLANNWRVHDLILAFYALDRPIAAECYGVTCLAFARDQEDRQSIIRGKHVTGHCIEYDYLDGVGDFNMGPPPYPLEYILRDAGGAYHGNFG-KTTSVIVDYPFITGRSTPDSYLTGQKTVEVL-------- +DEMKKALFFLF------------DGFAEFEVNLASLFLKSKGFEIVTASVDNATVTGE----GG------------------FQCKPHISIDGIIAKEYEILIVPGGEI--FHHLENPKLLSLAREINEQNKWLAAICAGTALLQAA-------DVLQNKRFSTSLTPEVES---------------LAHLHEW-KYKQ------STDVTVDGKIITAVGSA-YVEFAVEIIKQ--------- +---MNLLVIVD------------NNFQDVELTTVVSILKRSQFKIAFYNPCSRKATGQ----FE------------------IVKFNNLE-TSVNLKDYQAVFVPGGKAC-FSFKDNKEIIKKIRHFFDKDKWVFAICDAPNALRYN-------NLIKEQNYTSFPSAWS---------------------KELRNSYQ------NKGVVVFEKLITAKSSYYSQHLAFEIIRT--------- +---MKLLIITL------------ENFQDLELVGFLVTVKRAIFEISYFNLEKASVTGQ----FN------------------IVKLTTN--TTLNYQEYDAVYIPGGRAA-QQLRKDKKTLEVIKYFLDNNKWVFAICDVPNALYET-------GLLKGYKFVGYPIENQ---------------------QRPQ-FFQ------NKSVVVSKNLISAKSAEYAVKLGLKVIEK--------- +----------M------------DDFQDIELVTFIALVQKAIFQIDYFNPESKNVFGQ----FG------------------LAQIRTK--NKVNLQDYNSIFIPGGKGA-RRLRNDVISLEIIKHFFEKAKNVFAICDAPNALFEN-------NILK-QAFSSYPIDDL---------------------PKTT-LRN------ENTITISDYIITARNANSAAQLAYEVIKK--------- +--MKKLLVILL------------DKFQDIELTTFISLIKKAIFDIEFFNPKNKLVIGQ----FG------------------VVSIQAH--NHWKSDDFDAVFIPGGFAA-QLFRKDSKSIQLVSEFFAQNKHIFAICDAPNAIFEL-------KLAENYQFSSYPNQHN---------------------SKIR-LRQ------DSLVTIDRNYISARNAASSADFAFVVIEK--------- +--MNKLLVILL------------DDFQDIELTTFLSLVKKAIFQISFYNPKNKAVSGQ----FG------------------IVKIEAQ--NHWQSSDFDAVFVPGGKAV-QSLRTDQKTLNLINDFFENNKYVFAICDAPNALYEQ-------NIAKNLKFSSYPIENS---------------------QNYQ-NRV------EDKVCKTGNYFSARNADSATELAILVIEH--------- +---MKLLTILH------------DQYQDIEYSVVMSILDISTFTMDVYNP-QDRIYGQ----HK------------------TSYADVKDLSKVSHKDYDAIFILGGKNV-RRLADDQKTLKFIKDFYTSGKDLFVLCFASNVLFDS-------GIIN-EKYVGYPLQNQ---------------------K--RKNFT------ETIGIVDKNLFTGAGAFSSFELGFTIVDH--------- +--MKKILVIVY------------PEMNDVEYTNVMVVFSFITIQTTCYHHSLKKITAS----NG------------------VVEVNNIV-NTINLSEFDAVYIPGGIGA-THLDKDEKLLKTINYFKVNNLYLFAICDTPNVLFKH-------GIITDEIYSSFPNPNL---------------------V--MENRS------TAKVTVANKLITARSAGCALEFATVIVCT--------- +---MNLLVIIE------------DKFKDVELVTPLTIFKTSQFKIDFFSPNLKIATGS----DG------------------FAKIENIL-NNIDINDYDLIFIPGGSGA-QALRKNQESLKIIKEHFNSGKGIIAVCDAPNVLSEN-------KIITNESFSGYPTNWS---------------------VDFRENID------QFVTSENKKLITGNSPFSSTKLAFYALIH--------- +---MKLLVLTI------------KEFQDIELVSFASILTASKFKIDYYSPEEKSVVGQ----FN------------------VAHIKTI--KSFNVNDYDAIYVPGGMGA-IHLRTNQKGLAAVHEFVKANKWVIAICDSPNALSEN-------KILNEDKYISWSDGTM---------------------NHPNIKDF------NVQLNRSNKLITGRCSLTTLELAFYTLEV--------- +---MKLLALTM------------SKFQDLEMVALLSIFKASKFRIDFYSPENLMVTGQ----FD------------------IANIKTI--KNFNVNDYDVLYIPGGYGA-TLLRQSKKGIACVKEFIDNDKWVIAICDAPNALADH-------NLIKDQKYISWSSGDI---------------------TDSKIKDF------NTHVYRSNKLITGRCPVVTLDLAFYSLEV--------- +---MKILVLVH------------NHFNDIELGTTLAILSKWSIKITIYNPTIKQVVGQ----CN------------------VLKLDVEH--TFNFDEYDAIFIPGGKGA-QTLRKDTKSIEIIKKFRANQKYIFAICDAPNVLYEN-------KIIDSISYSSYPINTP---------------------FPFGAKRT------EALATVDGNVVTGRSPYATFEFSFKILET--------- +---MKLLVLTH------------PMFNDIELTTVLGCLIRSKMKITLYNHKHKSATGQ----FG------------------VTTLALEN--KVNLDEYDAIFIPGGKGA-QELRKDPESLKVIDYFIKNDKWVCAICDAPNVLYEN-------HFIDKVKYSSFPIIPL---------------------V--GKNRN------EKMVTVNNKIITGRCAASSMEFGLTLVKE--------- +---MNILVLLH------------DKFNDVEFTGFMACLIRSKVGIQYYNPTLKQVTGQ----FG------------------LTHLKIND--KFQYELYDAIFIPGGPAA-QDLREDKKSLEIVKKFYLDKKYVYAICDAPNALYEN-------DIFDDVRYSSYPMPNL---------------------V--ARNRT------EAMVTVGDHLITGRCAMSGVELGIAAVKQ--------- +---MKLLVVVH------------NKFNDMELVSVLSVLKRSQIKITYFNPSYKCATGQ----HG------------------IVTLNLVS--EVDESDYDAIFIPGGAGA-KELREDKESLEIIRNFKKLDKYVFAICDAPNALYEN-------GIITSEVYSSFPIENI---------------------NNTCKNRS------DNLVSQSNKLFTGKAAAAGTELGLLIIKS--------- +---MKLLTLVL------------DEFQDIELINVNATLQRGFLKNDFYNPHNKVVTGQ----FN------------------IANVNTI--TQINENDYDAIFIPGGKAA-QHLRKDSKSLNLIESFIKKNKIIIMICDAPNAIYES-------NLLKDIIFTSYPVESI---------------------LKLKIQRN------EDNVVYYKNFFSAKSAAFSIELGLKVIEV--------- +---MNLLVIVE------------EGFEDTELTGTLDLFHRANLKTTFYNPLGIEATGA----HK------------------IVKLQTTS--NINVDEYDVLFIPGGPAA-KSIRKNQTFLNLIAKFKNQNKLIIAICDAPNVLYEN-------KFIDKTKFSSFPINDS---------------------VKEISNRS------KELVSSDKKLITGKCAAAVFDFGLAVIEV--------- +---MKLLVFIE------------NQFNDIELTTPLSYLKRAKNEITYYHPHLSSAHGQ----YN------------------ISYIQNISNQIGDLDSYDAFFIPGGKGA-QSLRKNEHSLKIISSLIAQNKLVFAICDAPNVLLEN-------NLIPKYAYSSFPSDWS---------------------TAYQSFRS------EEMVSRANNLITARCAFASNELGLTMVEI--------- +---MNLLVITL------------DGFNDVELTGVLSCLSRSKVNFTYYNPEKSHVLSQ----YG------------------TYEINAKT--DVNFSEFDAVFIPGGPAA-IALRTNQKALNVIREFKNLNKDIYAICDAPNALYET-------GIIDEESYSSFPMYQDPI---------------EL--KLNTKNRN------DNLVTNNNHLITGRCASAAIDLGLEIIKH--------- +---MNLLVIIE------------DNFKDVELVTPLTIFQTSKFKIDFYNPTLKVAKGV----NG------------------LAKIENIH-NEININDYDMVFIPGGPGS-QDLRKNLKSINIINQLYEKNKKLVAICDAPNVLSEH-------KIIQNEKFSSYPTDWS---------------------SEYRSNTT------ELISKSNNKLYTGNSPYSSAKLAFMVIIE--------- +---MKLLVLVH------------NRFNDVELTGVVACLERTKLDIVYYNPKYTKAIGQ----FS------------------IIKLNMVN--KVDFNEFDILFVPGGPGA-QELRKDKESLKIIEKFIQNKKYVISICDAPNVIYEN-------HIIDSIPYSSYPIPNM---------------------V--ANLRN------DNMVTNKGKFLSGKCAGAAVDLGIEAVKE--------- +--------MAY------------PNYADFEIAHTLFFLRKKKARITTATIDGNFVISL----GG------------------LQTQADAGVFEIEVKKYDLVLISGGDGI-GEVMNEETIHTLLQEAASLHIPIASICTSAVLLGKA-------GLLKGKKFTCLLNTHAIF---------------Q---EVFVSEYT------GTDIEIQESFITAKGTA-FVEFTVAVGDM--------- +YQLIHVLFLAY------------PQYADFEIAHALFLLRKIKAKITTVSVNGKSVESV----GG------------------LRTHVEFSISEINIKNFDLILIAGGDGV-REIIEEEIVINMLSSAYNLDIPIASICASATLLAKA-------GILNGRKFTCLTSTYENN---------------K---TLFKSTYS------GADIEVEKSIITAKGTA-FAEFAVSICQQ--------- +DMKKRVLVYLY------------PQFREVEIMVALSAIS-RYYEVLTFSLPHGIITSE----CG------------------LFLQPSIKFKNINPLDFEMLILPGGRQ--AISQTDPRLLRLIKAFNRDGVRVAAIGTGVLMAARA-------GILAEKQYTASLSEEES-------------------DQEWPGKRV------NRSVVEDRTVITAKKNA-YIDFGLLLGDR--------- +---MKTFILVY------------PSFVQYEVILTSLFMK-TAGDIVTVGIDGSEVTSH----EG------------------FIVNPHMKLSNINLDDVDLFVIPGGEH--VNIYGNPILTKTLQGLSKKGKVIAAICSGPVHLAKA-------GLLDGKRYTSYRMPERK-------------------D--FKAKRV------EDNIVVDGNIVTAKAVG-YVDLALELGRI--------- +---MNTYVLVY------------NSFVQFEVVLAAYFMK-TQSEVHTLGLNSMPVISC----EG------------------FSINPSAVLGNIDVNAIDLLVIPGGEV--EELAANEGLLALIRSMNASGKPVAGICGGVTVLKAA-------GVLEGRSYVDNQEGREA-------------------AGLPDGASD------EVNVIRDGNILTAKPNG-YVDFALELGRM--------- +---MKTHILVY------------DGFSQFEVVLAAHLMK-RAGEIVTVGLSTEPIVAH----EG------------------FRILPHTTIERVEAFSVDLFVVPGGDL--SKITRRNELENLLKAIQSCGGKVGAISSGTLLILDA-------GLARDRRFTSPEPVEN-----------------------ALGNRI------DQPVVTDGSLVTAKSHG-YVDFALELGRL--------- +---MKSHVLIY------------DGYVSFEIMLATYFMK-TKGDIVTIGVTKDPVISY----ED------------------FKVTPSVAIDEVSAEDIQLLIIPGGDN--TPLKTNKQLLALINTLNNDHKVIATICSATELLEIA-------GVSYKNPV-----------------------------------NH------PTGLEIHKNIITAKPNQ-YVDFAIEIGKV--------- +---MKSHVLIY------------DGYVSFEIMLATYFMK-TKGDIVTIGVSKDPVISY----ED------------------FKVTPAVALDEVSAEDIQLLIIPGGDN--TQLKTNKQLLALIKALNNDHKVIATICSATELLELA-------GVSPKNHV-----------------------------------SH------PSGLEIHKNIISAKPNK-YVDFAIEIGKV--------- +---MKALFFLY------------DGYVDWEISPLAYIFSETDVTIETAGH-TEEIRHS----GQ------------------FVIRVDHNVNNCDVDDYDMLVIPGGDP--EPLIGDEALRTLIRSFHDKNKRIAAICGASALLGMS-------GVLEDIEYSTSLESEEF-------------------PDYLPVGRS------KTDVTVSGNVITAEGNA-YIEFAVAVAKE--------- +---MRALCLLY------------DGYIEWEISPLTYMLQVTDVDVDTTGV-QKEVKNC----GG------------------FRVQTDYLLHECDADAYDLLLIPGGEP--DSLYSEASLTTLIQHFHDQRKTIAAICGGTLLLGAS-------AIMENHTYSTSVEPEDL-------------------VGILEAHRS------LADVTVSDGIITAEGNA-YIEFAVAVMKH--------- +---MKALFLLY------------EGYVDWEISALSYILSVTDCEIETTAL-QSEVKHC----GQ------------------FTVKVTKTIDECTAGEYDLLIIPGGDP--VPLLEESKITTLIQEFDKKNKWIAAICGASTLLGAS-------SVLREREYSTSIEIEEF-------------------QAFFNTYKS------KTDVTVCENLITAEGNA-YIEFAIATGKQ--------- +---MKTHILLF------------EGYVSFEIMLASYFMK-TQGDVITVALDEGAFRSY----EG------------------LSVNPDLIMNQVDPSTVELLIIPGGDV--TSLLKRKELMNWLRILNGQMTPIAAICSGTLLLGQA-------QILEDKSFTTNAEAQMR-------------------D--TIGVYM------NTNVVVDGHIITAKANA-YVDFGIEIGKA--------- +EHSMTNYILIY------------DDCCFYEIVLLGYFMRYSNMGEQPCSPHRDTIRTA----EG------------------FRVQADTYLEDIDPEEVTSFIIPGGDI--SRVR-GEDLSAFLHSLDRDKSCICAICAGVDLLEEY-------GFLEGKNSI---------------------------------RTS------QDLAVSDGLLVTARPNG-YVDFAVEAGKA--------- +---MKDIVLLY------------DNCCIYEIVILNYFLKCTGSDLIFCSIDGKMARAM----EG------------------YSIHADMPLQDVDLSEVRSFIVPGGDI--ANID-RDIVYDCLRTLGDRGALVAGICAGVNVLDRA-------GLLKEIRST---------------------------------HSG------DFDCIRDGNVVTARANA-YVDFAIETAKA--------- +---MKTVVLLY------------PTSCIYEIVILNYFLHFAGKEVLFVSPDGTPITAM----EG------------------YSINVSGKLTDIAPDEIELAIVPGGNI--KAID-NPIVWNCLKDIKSRGGILAAICAGVDVLDHA-------GILDGVVST---------------------------------HSS------DLDVAVTDQVITSRANG-YVDFAIEVAKK--------- +---MKTVVLLY------------DTCCIYEIVILNYFLKVTGKDVSFVSLDGGKVTAM----EG------------------YSIQAEASLGEVKKEEVELLIVPGGEI--SKID-HKEVWDLIAAVHKNKQIVAGICAGVDVLEHA-------GILEEIVST---------------------------------HSA------DLDVAVSDHVVTARANG-YVDFAIEVAKE--------- +---MKDIVLLY------------DGCCIYEIVILNYFLQYTNSQVLFCFTEKPDIKSM----EG------------------YSIHADMPLSEAGCGDVRSFIVPGGMV--RQIE-TDLVLKTVKKLHQQGTLVAGICAGVDILEQA-------GILEGIPST---------------------------------HST------DADCIRAGNVVTARANA-YVDFAIEVGKA--------- +---MQSVVLLY------------PTCCIYEIVILNYFLKVTGGDVVFVSMDGNPVTAT----EG------------------YSMNVSARLTDIDAAQTKLMVIPGGDI--REID-QEIVYEYLRKVRDKKGILAGICAGVDVLQHA-------GVLEGIVST---------------------------------HSA------DLDVAVADQVITARANG-YVDFAIEVAKK--------- +---MKNVFLVY------------DDCCFYEIVILNYFMKFTGQDVVICSLNGSAITCM----EG------------------YSVNVDMALKDVEIDNIKSLIIPGGDI--KIIC-NEEVYELIKDLVKKEIIVAAICAGVDVLENT-------GVLKDTKST---------------------------------HSE------DTDIYNDKKVITARANA-YVDFAIEVAKE--------- +---MKDVFLLY------------DTSCFFEIVILNYFMSLTGCEIIYCSLDGQPVRAT----EG------------------YSVNVDMALKDVDPQQIRSFIVPGGDI--TFID-TDEVRTYLQELKSRKILIGGICAGVDLLAHA-------GILDSLEST---------------------------------QSS------DLDIVNDGHVITARANA-YVDFAIETAKE--------- +---MNVCIFYF------------EQFANHEIVFACHEFR--KQNILAVGLEKGIYQCT----EG------------------QKVVVEYGLDELSLDDIDVFIVPGGIT--ENIQDNPELLRFIAELHRRKTIIGGICGGTFILAKS-------GILKNTPCTGHFIRFEA-------------------GALFSADLR------DEDVVVHDNIVTAKGKA-FIEFALALADT--------- +---MNVCIFYY------------DGFCEFEVVHVAAEFS--SQNLVTVALENKVYASE----EK------------------QRFLPDKMINELNPYDIDLFIIPGGNP--SYLYDNSQLKDFIKSIDENNKIIAGICGGTELMAAY-------GLLDYKKCTGDSDGLKS-------------------DQFFKSTIL------NEDIVVDGNIITSTGQA-FIEFAFKLADI--------- +---MNVCLLYY------------EGFCEFEVVFAANEFR--D-SMFSAALENRIYISE----EK------------------QKFLPDKVIEDINPEDIDLFIIPGGES--SKLYEEIELKEFILKLNEKNKLIAGICGGAELMAYY-------GLLDNKKANGDSAGFKV-------------------DNIYDVNIV------SKDVVKDGNCITAIGKA-YVEFAIELGKV--------- +---MNVCIFYY------------DGFLGYEIMFAASLFD--EKNVFSAALENRPYISG----EK------------------QRFLPDKIISELNPDDIDVFIIPGGAGN-DNLYNNSILRDFMTKLNSSKKVIAGICGGVFLMANY-------GILDNKKCTGDGEGIQL-------------------DYLFNSHVV------NEDVVIDENIITSTGQA-FMEFAFAIAKK--------- +--MKKILMLVY------------PSFAEFEITVATSVLRND-YVVDTVGLTKDIVKSE----TG------------------LQVKPHYELSDICVDDYEGMIIPGGDV--VHLKDSEGLCELVRQLYKKEKLIAAICAGPFVFANA-------GVLNQHPYTVTLNY--------------------RELDCFSEHFV------YEDIVQHKNIITAQGHA-FVEFGLVIADY--------- +RAMKKILLFVY------------PTFAEFEITVATALLRNK-YEIITAGLTKEMIISE----TG------------------LQVQPHIELGEVRVEEYEGIIIPGGDA--IHMEDAEVLFSVIRQFHEQEKLVAAICAGPYALAKA-------GLFKENSYTVTMDY--------------------RKLDCFPENFV------YEEVVQHSNIITAQGHA-FVLFGIAIASY--------- +------------------------------------MLKNK-YEIITAGLTKELIISE----TG------------------LQVQPHIELSEVRVEEYEGIIIPGGDA--IHMKDAEGLFSVIRQFHEQEKLVAAICAGPYALAKA-------GLFKENPYTVTMDY--------------------RKLDCFPENFV------YEEVVEHSNIITAQGHA-FVPFGIAIASY--------- +--MGKVLCFIY------------EGMTDFEMTFACHLLKLFEKELFTIAYDKESVSGT----SG------------------IKYLPDFTVNEVLNNDVEALIIPGGWS--SGD--RKEIFTLIKKLHSEEKLLCAICAGPIYLAKA-------GILKGYSYTTTLERENLK---------------NL--DPFPETYV------DKGVIRDRNIITAKGNS-FVDFGVEIFDA--------- +--MGKILCFVY------------ERMADFEMTLACHMLGWDEKQLVTIGYEKAPIIAA----SK------------------IQYLPNISVKEAINDDVDALIIPGGFE--REC--KDELVELVQKFHSEKKLICAICAGPEFLAKA-------GILNEHLYTTTLSEDYFK---------------EN--DCFPQNYL------EEKVVRHENVITAKGMS-FVDFAIEILDY--------- +--MRKVLCYIY------------DGMADFEISLLLHRLKNTKKEIISISENVEAIVAQ----SG------------------LRYIPDMKIDDIRCEDVEALIIPGGPI--DNN--QNCICKLANDIINSGKLLAAICFGPQFFGRA-------GILDNYIYTTSCSVEKIK---------------QL--DPFNEKYV------HKRTVVDRNLITAQGYA-FVDFAMEVCKY--------- +--MSKILCFIY------------NDMADFELTMATTAVSWLKMDVVTIAYTNETVTAR----PG------------------LQYQPHMTVKDAINEDVAGIIIPGGWN--SEQ--QPELIELITKLYSDDKLVSAICAGPQFLAHA-------GVLNNRKYTTTWTEDHLK---------------EQ--DFFPENYV------IQNVVRDQNVVTAVGHA-FIDFAMEIIDY--------- +--MKKIALFIF------------EGMADYQITFVSHLISSSAYELVTISYDKNPVKGV----SG------------------ITYMTDMVLEDIEYEDFEGIIIPGGWS--GDY--RNELGDLILYFKDNNKLVAGICGGTIYLAKA-------GALENVTYTTPIKKWTDK---------------YKEIDPFNENYV------KAHVAKDLNVITAKGNS-FIDFSMEICDF--------- +--MGKILCFIS------------DDFADFEITLALHKIRNVKKEVLSVGYSYESVVSE----SG------------------LTYQPDLVLKEAVKNDIEGLIIPGGPI--VNQ--KQDLTDLINHLDREEKMLAAICHGPQYLGRA-------GILDHCKFTTSCSVERIS---------------KL--DPFPDNYV------DKRVVRDEHIITAKGRA-FVDFSFEIFDY--------- +--MGKILVFMY------------NDMADFEVIYATHLLGHESKEIVPCAYHMEPVKSK----GG------------------MVFLPSVTVAGAKVEDYEGFIIPGGWN--PVV--REEMLELIRGFYNSGKLLAAICAGPRFLAKA-------GILDKVKYTTSIVEWNEM---------------RRAQDPFPENFV------NARVVRDGSVITSKGIS-FVDFAVEVADY--------- +--MEKVLCFIY------------EDMVDFEMTLACHL---VNKEVIPIAYEIKIIKSN----SG------------------MCYYPMATVKEALKTDVAGLIIPGGEN--DEQ--RPELTELINKLNDQSKLLAAICAGPQYLARA-------GILKGKKYTTELTPDKLK---------------EYFPDPFPDTYV------NENVVRDNNIITAVGNA-FVDFSVEVSDY--------- +--MGKILFLIF------------DEMTDYEVTFISHLLSSEGKEIITISYEDKMIKGR----SG------------------FLYKPAKLVKDVLNYNVDGLIITGGWY--GEV--RPELIELIDKIYLDGKLVGGICGGTVFLAKS-------GILNNVKYTTPINQWTQK---------------HIDIDPFPENFI------SERVVRDKNVITDQGTA-FIDFAIEICDW--------- +--MGKILIFMF------------EGMADYEVTFISHLLHADGKEIMTIAYTDDAVEGQ----SG------------------LHYQPQYTVKEVLKEDVEGLILCGGWN--NDI--RLELVELIQRIHKERKLLAGICSGTVMLAKA-------GVLDYMTYTTPISKWSAE---------------EALFDPFPENYV------SKRLVRDRHVITAQGIA-FVDFALEICAW--------- +--MKTILCFLY------------ESFVAFEATLACYYINLEDFQVKYIGYEKTPIKSS----GG------------------ISVRIDKTVEEITSKDIEGIIIPGGND--RIL--KPELELLIKKLHEDKKMIAAICAGPEFLAKC-------GILDGRKYTTTVPPSEYV---------------EK--DPFPETYV------ETRMIRDGNIITAKIGA-FVDFALEIWDF--------- +--MKNILCFVY------------DSFVDYEISLVCTEINLDNCQVIYISYQNSYVKSS----AG------------------LKLKPDKIIAEIESNDFNGLIITGGYN--REL--KTELEQLMFKLNNEKKLIAAICGGPEFLAKA-------GILNGRNYTTSMPPNEYE---------------EQ--DPFPETFI------DSRMVRDDNIITAKGHA-FVDFTLEIWEW--------- +--MKKALLLTY------------DTFADFEVMILLTCIDSKQINSFTVENEIRPIQSC----AG------------------FQVIPHLTIDQVNPEDFDVLIIPGGNP--APILDNAELKKIVQHFYSEKKQIAAICGGPAILGAA-------GILEEVKYTASLDTDDPL---------------YSHV--LVKNQL------KEHLVIDKNVITSTGSN-YLNFAEAVLRN--------- +--MRKVLLVLV------------PGVESMEFSPFLDIFGWNMLHLEICSL-EERISAS----WN------------------LKLQSELNIKD-ELSEYSAVILPGGFGK-YHYFENKDFQSLIAGALEQQLYIIGICTGSILLAST-------GYFEGKKMTTYLYENGRY---------------SKQLAGYKN-FQ------NSIFCKDERVWTSSSPATAIPLAFDLLEE--------- +--MKKILLLLA------------DGFESYEASVFTDVFGWNYEELFSVGL-HDTLKCT----WG------------------YSCVPNYQLSEINLDDYDALAIPGGFEE-ADFYADEQFLNVIRYFDSRNKPIAAICVAALSLGKS-------GVLKGRSATTYYYPNNPR---------------QKQLEDFGI-VL------KKSIVVDRNIITSSSPATALDVAFWLLEQ--------- +-----------------------------------------MEELVTVGL-RDRLKCT----WN------------------FTVIPEFTLGEVELAEFDALVIPGGFEE-AGFYEDPAFLDVIRHFDTHEKWIGTICVAALALGKA-------GILQGKRATTYNGVGSVR---------------QAQLKDFGQ-VQ------QDPIVVENHIITSHNPSTAFDVAFLVLEK--------- +-MIMKLLVFLA------------KGFETIEFSAFIDVMGWATDDVVTCGL-NQKVISS----FN------------------VPVLVDKVMDEVSADEYDALAIPGGFEE-FGFYENEQLLELIRLFDSQKKWIATVCVGALPVGKS-------GVLNGRKATTYHLRGAHK---------------QKVLQGFGT-IV------NSPIVVDDNIITSYCPQTSYGVALLLLEK--------- +---MRLLVFLA------------KGFETIEFSAFIDVMGWATDETVICGL-NSKVVGS----FN------------------VSVLVDKTIEEVSADDYDALAIPGGFEE-FGFYENEKLLDLIRQFNSQKKWIATVCVGALPVGKS-------GVLTGRRATTYHLRGAHK---------------QKVLQEFGT-IV------NEPIVVDDNIITSYCPQTSYGVALLLLEK--------- +---MKILLLCA------------KAFETLEFSAFIDVMGWAEDSIDICGF-EKIVTST----FG------------------VSVMMDVLIDDINVEEYDALAIPGGFRE-FGFNEDVRTLDLIKKFDYYEKPIASVCVAAFALAES-------GVLKGRNATTYHLDNGKT---------------QGELAKYGN-II------NKPVVIDKNIITSYCPETAPEVAFKLLEM--------- +--MAKILLFLN------------KGFETMAFSPFVDICGWANDHVTTVGF-TKQVMST----FK------------------IPVIVDELITDIDARDYDALPIPGGFEE-YDFYDSEPFLELIRQFDKAHKPIASICTGALPIGKS-------GVLANRRGTTYHLSNGHR---------------QQQLAKYGH-VV------NEPLVQDDNIMTSYCPQTAASVGFWLLEQ--------- +---MKILLLCL------------KAFETMEFSPFIDIMGWADDHVDICGF-NPKILST----FG------------------VTITADILIDDVDVNNYDALAIPGGFEE-YGFYTHDKTLNLIRSFYSQHKPIASVCVAAFPLAKS-------GILNKKKATTYHLRGGYK---------------RKELEKFGI-LG------DEWLAMDDNIITSSCPRTAPDVAFRLLEL--------- +MQKKKVLLFLA------------KAFETMEFSAFIDVLGWAVDFVDTCGF-TEKVIST----FN------------------VPVIVDKTINEINIDEYDALAIPGGFEE-FGFYEDERFLDLIREFNAKGKIIATVCSGAFPLGKS-------GILKNRRATTYHLRDGHW---------------QNKLKEFGN-VV------NEPIVVDGNIITSYCPETAPNVAFELLKM--------- +MENKKVVVFLA------------KAFETMEFCTFIDVLGWAVDIVDTCGF-TEKVIST----FN------------------VPVIVDRTIEEINVDEYDALAIPGGFGE-FGFYEDERFLKLIKEFNAQGKIIAAVCSGAFPVAKS-------GVLQNRKGTTYHLKNGYW---------------QNKLKELGN-VV------NEPVVVDGNIITSYCPETAPKVAFELLKM--------- +--MKRVLLLLA------------DGFEAVEASVFTDVLGWNLEQVVTTGL-HDRLKCT----WN------------------FTVIPEVTLDSVRVDDYDALAIPGGFEE-AGFYKDPRFSAVIQAFHAQDKWIATICVAALTLGKA-------GLLEGRRATTYDHPTSIR---------------KKQLREFGI-VV------DEQVVVDGNLITSCNPATAFEVAFTLLEK--------- +--MKRVLLLLA------------DGFEAVEASVFTDVFGWNIEELVTAGL-REELKCT----WN------------------FRVKPEMLLQDVKVEDFDALAIGGGFEQ-AGYFTSKEFQDIIQQFHQQKKIIGAVCIAALALGKS-------GILKGKKATTYSYPGSTR---------------KQELQKFGE-VV------QAPLIDEGNIITCASPSVGFDVSFLMLEK--------- +-MTKRIMMLLA------------DGFEAVEASVFTDVLGWNFEELVTVGL-REQLRCT----WN------------------FTVVPEYTLDQVDLASFDALVIPGGFEE-AGFYEDEAFLDVIRYFYAQDKWIATICVAALALGKS-------GILQGKKATTYNGVGSVR---------------QAQLREFGE-VL------QDPIVMDGKIITSYNPSTGFDVAFLVLEL--------- +--MKKVLLLLA------------NGFEAFEASVFADVIGWNLEELLTTGL-HEEIKST----VG------------------FAVKRELLISEINVDEFDALAIPGGFEE-KGYYDHEDFLNLINKFHESNKIIASICVGALPIAKS-------GILKDKNATTYGLGQSTR---------------QKQLSDFGN-VI------PQSMVVDGNIITGYNPSASFEVTFYLLEL--------- +--MKRILLLLA------------NGFEAVEASVFTDVLGWNWEEVISVGM-HEQLQCT----WN------------------FKVTPEKLFHDIILDDFDALAIPGGFEE-AGFYESEAFQAVVRHFDEQKKPIATVCVASLILGQS-------GILHNRQATTYNHPTSKR---------------LAQLQSHGV-IV------NERIVQTEHIITSSNPGTAFDVAFTLLEM--------- +--MKKILLLLA------------DGFEAVEAGVFTDVFGWNWEQLITAGL-HKQLTCT----WN------------------FTVIPEVVVTEIDLEEFDALAIPGGFEE-AGFYNHETFLEVIRHFHAKQKPIASICVGSLPLGKS-------GILHNKKATTYNHPTSHR---------------KEQLQVFGN-VQ------HAPIVQDGHIITSSNPATGFDVAFLLLEQ--------- +--MKKVCLLLP------------NGFEAVEASVFTDVLGWNITEVITVGT-RDKLKCT----WN------------------FLVTPEMHISELRVEDFDALAIPGGFEE-ANFYEREDVLNVVREFNNQGKPIATICVAALILGKS-------GILEGRKATTYNLSNGHR---------------QKQLADFKN-VI------AEPIVVDKNIITSFNPSTSFDVAFKLLEV--------- +--MKKVLLLLA------------NGFEAVEASVFTDVIGWNLEDLVTAGL-HDKIKCT----WN------------------FTIIPEININDVNIDDFDALAIPGGFEE-AGFYDNEDFLNLIREFNKAGKIIASICVGALPIAKS-------GILYGRSATTYNSPASIR---------------QRQLKEFGN-VI------SKPIVMDQKIITSYNPATAFDVAFMLLEL--------- +--MKKVLLFLA------------QGFEEYEAAVFTDVLGWSVVEVVTAGL-RPEIQCT----WS------------------LIVKPQAQLKDLDLAEFDALAIPGGFQR-AGFYEHEDFLEAVRHFDKTGKPIAAICVGAMPVGKS-------GVLTGRNATTYHLVNARR---------------RKQLAEFGV-VL------DQHVVVDRNIITSTGPATGLEVALILLEM--------- +--MKKIAVFLF------------EGAELFEIATFTDIFGWNVVKLETISY-KESIKCT----WG------------------GEIKVEKVITENIFFDYDALIIPGGFGK-ANFFENEIFKKLIKYFSENNKIIVAICSAVINLLES-------GYIKDKKVTTYLLGNKRY---------------FNQLKNYTI-PV------EEEIVIDNNLFTCSGPGNTLELSFRLLEK--------- +--MKKILLLLA------------KGFETYEASVFIDVMGWNLDKIVTCGI-NREVVST----FG------------------LVVHTDITLEEVNVDDYEALAIPGGFEE-YGFYESEEFLNLIREFYNKDKIIASICVAALPLGKS-------GVLTNKRATTYNLNNGNR---------------QKQLKEFGD-VI------NEPVVVDGKIMTCWNPSTAIDVAFKLLEF--------- +--MKKVLLLLA------------NGFEFFEASVFIDVIGWNEEKLYTCGV-TKEVKSS----FD------------------QTLVVDYRIDEIDVNDFDALALPGGFEV-YGFYNSDKFLDLIRAFRTGNKVIASICVGALPLAKS-------GVLKGKNGTTYRS--TVR---------------REALQNFGN-VL------DQPIVLDDQLITSWNPSTAVDVALLLLEL--------- +--MKKVLLLLA------------KGFESFEASVFIDVIGWNVEKLYSCSF-AKEVQGS----FG------------------VRFNVDFLIGEVNVNDFDALAIPGGFEE-YGFYELPKFLELIRDFDRQGKTIASICVGALPIAKS-------GVLNKRMATTYNHKNSIR---------------QKQLQEMGN-VQ------NTPIVIDKNIITSWSPATATGVALLLLKM--------- +INMKKVLLLLA------------NGFETLEASVFIDVIGWNIDQLFTCGR-TKEINST----FN------------------QKIIVDYTFNEINIDDYDALAIPGGFIE-YDFYDNEEFLEIIREFDRNGKIIASICVAALPIAKS-------GVLKGRKGTTYNKKDGIR---------------QKQLKDFGE-VV------NQPIVIDRNIITSWNPSTAMEVAFILLEK--------- +--MKNILVLIS------------QGVEILEVSPFIDVFGWNVVLVTTCSF-HDIINCT----WN------------------IKILPEINLKNTNLEIYDALVIPGGFGK-AGFFNTEEFQSIIQHFHNNNKIILGVCTGVISLGES-------GILKNKRATTYLLDNDRY---------------FKQLSNYGI-PV------REEIVIDDNIITSSAPKNALETAFILLEK--------- +--MKKIFLLIS------------QGTEILEVAPFIDIFGWNIVILKTGGF-HSIISNT----WN------------------LKIVPEIDLKSTDIDEYEALVIPGGFGF-KGFFEKEKFKEIVQSFYEKDKIVVGICTGVISLGEA-------GILKERKATTYLYDNNRY---------------FNQLEKYGI-PI------REEIVIDKNIITCSAPKNAIEVGFLLLSL--------- +--MKKILIFAS------------NGFESLELSPFIDVFGWNIVFPTICAI-HDVLSAT----WN------------------LKIIPEVNLLKTNLDEFHALIIPGGFGK-AGFFNSETLNSLLNHFISNKKTIIGICTGALAIGIH-------GYLKNIPATTYLLDNERY---------------FKQLEQYNI-PI------KKDIVISDNIITSSGPGTAIDLAFYLLEK--------- +--MKKILLLLA------------NGFEAYEASVFTDVLGWNLEEVITAGI-RPYLQAT----WN------------------FNVTPEKLVQDLNLEEFDALAIPGGFEE-AGFYEGEIFSKIIRHFNQYKKPIASICVASLALAHS-------GVLYGRKATTYSHPTSIR---------------MAQLASYGH-VS------TERIVVDEHIITSSNPGTAIDVAFLLLEM--------- +---MKVLVLLL------------KGFETMEFSVFVDVIGWAEDKVETCGL-NKHVTST----FG------------------VPVIVDKLLDEINIDEYDALALPGGFES-YGFYETDKVSQFIREFYNKDKIIASICVAALILGKS-------GILNGKKATTYRLRDGHR---------------QKQLEAMGITLK------DQPIVVDGKIITSYNPQTAPHVAFKLLEL--------- +MKTKKVLLLLS------------NGFEAYEASVFTDVLGWNQKEVITCGG-REKLKCT----WN------------------FTVIPEMLLSEVDLNMFDALAIPGGFEE-AGFYTSDEFLSVIREFDRANKIIASICVGALPVGRS-------GVLKGRKGTTYHLNNGYR---------------QDQLASYGE-IV------DQLMVIDKNIITSSCPSTALNVAFTLLEM--------- +--MKRILMILA------------NGVEPMEVAAFTDIMGWALIKLIHAGL-RPNIVTT----FG------------------LKLSIDNLLSDLDLNDYDALALPGGFGP-AGFYESEPYLSAIKHFADAGKPIASVCVSSISLGMA-------GVLVGKNATVYHKVGGMR---------------KQQLVDTGQ-FV------DRPVVVDGNFATSSGPGTAVEVAFWLLER--------- +--MNKILLFCC------------KGFETMEFSPFIDVFGWANDEVVTCGF-TKQVEST----FG------------------VNVLVDKQIEEINTEDYDAIVIPGGFEE-YDFYSDEGLSNLICEFEKNGKYIVSVCVGALAIAKS-------GILKGRKATTYHLGNGQR---------------QKQLSEFGV-VV------DEPIVVDEKIITSWCPQTAPYVAFQLLEY--------- +-MTKKILLLLC------------KGFEVMEFTPFVDVMGWAEDQVVTCGLYNKMVTST----FG------------------VKVQVDVLLGEVSLDEFDALAIPGGFEN-YSFYESEDVSQLIRDFDSKGKHIASVCVAALALGKS-------GILKGRNATTYRNSHSVR---------------QQQLRDFGN-IA------DQSIVIDKNVITSYNPQTAPYVAFELLSR--------- +GGSMKTLLFLA------------KGFETMEFSVFIDVLGWANDTVTTCGF-QKEVLST----FG------------------VPVIVDTLIDEIDPDDYDALAIPGGFEE-FGFYEDEKLLHLIRCFDEKEKPIASVCVAALPLGKS-------GILKGRKGTTYHLRDGYR---------------QKQLEQFEE-IV------NDPVVIDRNVITSYCPQTAAQVAFSLLEK--------- +--MTNVLLFLN------------KGFETMEFSPFIDVCGWSNDNVTTAGF-TSVVSST----FD------------------VDVMVDKVIDEINIDDFDALAIPGGFEE-YGFYQSDEFLNLIRQFHDAGKLIATICVGALPVGKS-------GILKGKNATTYHLKNGYR---------------QKELKTFGN-IV------NEPIVFDNNVITSYCPQTAARVAFKMLGL--------- +--MKRVLLLLC------------KGFEIYEAAAFYDVLGWSAYAVVTVGL-RKEVQGS----FG------------------IRVIPDRLLSEAHPEDFEALAVPGGFET-HGYYESEPVADLIRRFFAMEKPIASICVGALPLANS-------GILKGRQATTYHLLEGIR---------------RKQLASFGH-VI------DKPIVWDENVITSTSPATAMEVAFALLAR--------- +HKIKKVILFLC------------QGLEEYEASVFTDTIGWTTYELVTVGL-RQKIKCA----WN------------------FTIEPAYQLHEIDDDSFDAIAIPGGMSR-AGFYEHERLLNIIRKFHAKNKIIASVCVGALAIAKS-------GALQGRTGTTYHLS-SKR---------------QTQMLEMGN-VV------QRPIVVDGNIITSQSPATAINVAFTLIEK--------- +KRNSKVILFLC------------NGVEEYEASVFTDTFGWTTYQLTTVGF-HQRVKCA----WN------------------FTIEPECLFDEIDIEEFDALVIPGGMSR-AGFYNDPRLLAWIKDFDAKGKVVASVCVGALSIAKS-------GVLSGRNGTTYHLS-QKR---------------QLQMQEYGQ-VL------NQPIVIDGNIITSRSPSTAMDVAFLVVEM--------- +KRNSKVILFLC------------NGVEEYEASVFTDAFGWTTYQLTTVGF-HQRVKCA----WN------------------FTIEPECLFDEIDIEEFDSLVIPGGMSR-AGFYDDPRLLALIKDFDVKGKVIASVCVGALPIAKS-------GVLSGRNGTTYHLS-QKR---------------QQQMQEYGQ-VL------NQPIVIDGNIITSRSPSTAMDVAFLVVEM--------- +---MHVAVLLY------------PGCIFFEIALAAETLA-GRCTLSYYTPDGEPHRAS----NG------------------ATLVPAGDLSALKSAALQAVLVPGGDP--RSLMLPVPRSEALRAQAATGALVAGICAGNLVMAGA-------GLLVGRRGTHNYTAEHAP---------------PAKVHFWDMQFV------RADLVQDGRLITAQPWA-YRQYAAAVART--------- +-MKKKVLVLLY------------PGCIEFEIKAALELLA-NQCEIYAVAPEKGTLHGS----SG------------------LLYQINMSFEEALKENFDCLLVPGGDP--GSVVENQALSQLLKNASQSGSIIGAVCAGPLLLAIA-------GILKGRKQTNAAF---Y-------------------PHVWDSQLV------REQVVIDQNIVTALPEA-HIDFAAETGWL--------- +--MNKIFIFIY------------DGMADFEMTLIAHILGTDGKEIVTIAYENHIIRSL----SG------------------LEYKPKGLVKDVVKDDVDGLIIPGGWN--GEL--RPELIELIKNVNSEGKLLGAICGGPYFLAKA-------NILQNRKYTTSMIEWTEM---------------HKQQDPFPESFV------NERVVVDKNLITSQGVA-FIDFTCEVCDW--------- +IMTKRTLVLLY------------PGAISYEVMYAIECLG-AYGKVDITTPENHNHTDS----SG------------------LRICPTVNFEDVCITDYQALLIPGGNP--DSIMGSDQISF-IQKAHESSLVIGGICAGVLVLARA-------GILKGVKITHNYTEKYAP---------------ESSVPYWEAIYE------ESLVQVDKRIVTAMPNG-YVDFGLAVAEA--------- +--------------------DQSTGFFLMELAKPLSKFLSAGCEVTFASPLGKTTPDPNSLMAFAL-----NFYERRENDLINGFTSPRTFSDEELDGFAAVFIPGGHVPLADLGADPELGRILANFHHEGKPTAVICHGPYGLLSTKATPEGTFLYKGYKITSWSDAEG------------------------------------------------------------------------- +--NKKVLMIATDE-RYIQMKFFSTGNHPVEMLLPMFHLDNAGFEIDVATLSGNPAKLEMWAMPKQE-QVVLDTFQ----KYADKLKNPLKLADIENSPYAAVFIPGGHGVLAKIPHSLEVKKVLKWAVEQDKFIITLCHGPASLLAAAVDEPENYIFKDYQ---------------------------------------------------------------------------------- +----------------------ADGSEEIEFVTPYDVLTRAGFEVQSVDLKNEYAHMTRNVRI------------VPDHTNLT-----SFPHQLAHEHYDILILPGGGPGAKTFSTNPSVLQLIKSFVRSGKFVAAICAGTTALVAA----GI----EKKIVTSHPSVMQ-------------------EIKGAGWEYSE------ERVVVDGKVVTSRGPGTALLFSLTIVEV--------- +----------------------ADGSEEIEFVTPYDVLTRAGFEVKSVSLQNEYAHMSRNIRI------------VPDYPNQN-----SVPLQPAHEHFDVLVLPGGVPGSKTFCESDAVLKLIHDFQQAGKWVAAICAATTALVASTKKFDK----EKKRVTSHPSVAE-------------------EIKVAGWQYSE------DRLVVDGKVITSRGPGTAMLFALTIVEV--------- +----------------------ADGSEEIEFVTPYDVLTRAGFEVKSVSLQNEFAHMSRNIRI------------VPDYPQLL-----SVPSQTAHEYFDVLVLPGGGPGSKAFCESDAVLELINNFGSAGKWVAAICAATTVLVASAKKFES----EKKRVTSHPSVAE-------------------DVKVAGWQYSE------DRLVVDGKVITSRGPGTAMLFALTIVEV--------- +----------------------ADGSEEIEFVTPYDVLTRAGFDVTSVSLKNEYAHMSRNVRI------------VPDHSNLS-----WVGFQTAHEDFDVLILPGGAPGAKAFCGSDEVLELISKFRKGQKWVAAICAATTALVASAKKFEG----AKTTVTSHPSVAE-------------------EIKQAGWEYSE------DRIVVDEKIVTSRGPGTAMAFALTIVEA--------- +----------------------ADGSEEIEFVTPYDVLTRAGFEVTSVNLNNEFAHMTRNVRI------------VPDHANME-----SLGCIQAHEEFDIVILPGGAPGAKTFCGSHPVLDMVSQFRKAGKWVAAICAATTALVAAEEKHGD----GKVKVTSHPSVAQ-------------------EIKDAEWTYSE------ERCVVDGKVITSRGPGTALLFALTIVEC--------- +----------------------TDGSEEIEFVTPYDVLTRAGFKVTSINLKNDFVTCTRNVRI------------IPDTTTPP-----ES------PEHDILILPGGGPGAKTFCQSDVAQRLIRSYRDAGKYVAFICAATTALVASVKTEGL----EAVKVTSHPSVKN-------------------EIVNAGWDYAPD----NERVVVDGKVITSRGPGTAMGFSLKIVEV--------- +----------------------ANGSEEIEFVTPYDVFVRAGIQAVSVELTE-WAVASRGVKI------------VPDTTVQE-----LPPVDALAEEYDILVLPGGAPGAKTFCGSEKVKEILRAFGKEGKIVGTICAASTAIKAAGLHY-------SKSLTSHPSVKD-------------------ELT-SDYEYKE------DRIVVDGNLVSSRGPGTALLFALTIVEK--------- +----------------------ADGTEEIEFVTPYDVLTRAGITVRSVNLKNEFAVCSRNVKI------------LPDAPSLD--------EKLRAEEFDALILPGGAPGAKAFCDSKTVLQLLRDFREKGKLVGCICAGTTALVKSVETEGG----ERVKVTSHPSVKE-------------------GIVGKGWDYSE------ERVVVDGGVVTSRGPGTAMLFALTIVEQ--------- +----------------------ADGSEEIETVTPLDVLVRAGFAVTSVGLKNPYAQCSRGIKI------------IPDIPSPH-----EIPDRLV-DAADILILPGGAPGAKTFCQSEEVLRLIREFRNEGKWVAAICAGTTALVESVKRADG----EKCKVTSHPSVKQ-------------------EIVDAGWTYADD----SERVVVDGKIITSRGPGTALLFSLTIVEQ--------- +----------------------TDGSEEIETVVSVSVLRRAQIDVTVITLQNEYAKCNRGVKI------------VPDQSLSN---------ISNFDIYDVIVIPGGLNAAKAISSNPEVQKLLASMHQAGKFVAAICAGTLAIKSANINK-------GGKITSHPIVKA-------------------DLE-NEYSYQE------DRVVVDNKVVTSRGPGTALLFALTIVEL--------- +----------------------ADGFEDIEGLTVVDLMRRAGIDIQTVSIKETEIRTSHGIDL------------LTDRTFGE---------C-DFSDADMLVIPGGMPGTKYLEEYKPLTELLTDFYQNGGKVAAICAAPGIFERLGFLK-------GRNATSYPSVME-------------------QLK-SA-RTSL------EPVVVDGNVTTSRGLGTAIDFSLSLIGQ--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKTVSVTGSFVETSHGVTI------------KADLRFED---------VESFEDADMLMIPGGMPGSTNLNEHEGVRQALIAQHKAGKRVGAICAAPMVLGSTGILD-------GKKATCYPGFEQ-------------------YFD-ASTEYTG------TLFQEDGNVITGEGPAATLPYAYQILSY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKMVSITGNFVETSHGVTV------------KADLQFEE---------AGDFSDADMLLLPGGMPGSTNLKAHEGVKAVLKQQHRAGKRIGAICAAPMVLAECGILD-------GKKATCSPGFEQ-------------------YFN-ASTTYTG------ALYQEDMNVITGEGPAATLPYAYRILSY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDVKTVSITGDFVETSHGVTV------------KADIKFED---------VADFNDADLLLLPGGMPGSTNLNAHEGVKTALKKQFEAGKRVGAICAAPMVLASCGILD-------GKKATCSPGFER-------------------YFN-ASTTYTG------ELVQVDGNVTTGEGPAASLPYSYTLLSY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKTVSITGSFVETSHGITI------------KADLKFED---------IQDFSDADMLLLPGGLPGSTNLNEHEGVRQALIAQNKAGKRVGAICAAPMVLASTGILD-------GKKATCSPGFER-------------------YFG-ESTTYTG------ELFQEDGNVITGEGPAATLPYAYQILSY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKTVSITGSWVETSHGVTL------------KADLRFED---------VKDFGDADMLLLPGGMPGSTHLNEHEGVRQALIAHHKAGKRIGAICAAPMVLASTGILN-------GKKATCYPGFEQ-------------------YFA-ADTEYTG------HLYEEDGNVITGEGPAATLPYAYKILSY--------- +----------------------ANGFEEVEALAPVDILRRGGVEVKTISVTGNLVESSHGVTI------------KADLLFEE---------ISNFSDVDLLMLPGGMPGSKNLNEHDGVRKALKEQFESGKRVAAICAAPLVLASVGLLK-------GKKATIYPGMES-------------------YLG-DDAEYTG------ALVQEDGNVTTGGGPAASFPYAYKLLSY--------- +----------------------ANGFEEMEALAPVDILRRGGLEVKTVSITGSEVTSSHGVTL------------LADLRFED---------AGHFDDADMLLLPGGLPGSTHLNEHEGLKALLRRHHQAAKRIGAICAAPMVLAGCGILD-------GKKATCSPGFER-------------------YFN-ASTTYTG------TLFQEDGNVITGEGPAATLPYAYQILSY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKTVSVTGSFVESSHGVTI------------KADIKFED---------A-DLRDADMLLLPGGLPGSVNLNEHEGVREALKRQNAAGKRIGAICAAPMVLASCGILD-------GRKATCSPGFEK-------------------HFN-ASTTYTG------ALFQEDGNVITGEGPAATLPYAYRILRY--------- +----------------------ANGFEEIEGLAPVDILRRGGVDIKTVSITGSFVETSHGVTV------------KADLKFED---------VADFNDADILLLPGGMPGATNLNAHEGVKAALKKQIEAGKRVGAICAAPMVLASCGILD-------GKKATCSPGFEQ-------------------YFN-ASTTYTG------ELIQEDGNVITGEGPAATLPYAYKILSY--------- +----------------------ATGFEEMEAIAPIDILRRGGVEVCLVSVTGNMVRSSHGVNI------------EADALLED---------IANFDDADMMLLPGGMPGSTNLNEHEGVRKVLLEQFESGRLLGAVCAAPLVFASIGILN-------GKKATIYPGMEA-------------------YLI-NGAEPTG------ALVQVDENVTTGAGPVAVLPYAYQLLSY--------- +----------------------ANGFEEVEALAPVDILRRGGVEVKMVSITGSLVESSHGVVV------------KADLLFEN---------ITDFSDADLLMLPGGMPGSKNLNEHEGVRKALKEQFEKGKRIAAICAAPLVLASVGLLK-------GKKATIYPGMES-------------------YLG-EDAEYTG------ALIQEDGNVTTGAGPAASFPYGYQLLSY--------- +----------------------ANGSEEIEALIPVDVFRRGGVEIKTVSITGSLVEMAHGVTV------------KADLKFED---------A-KLEDADLLMLPGGLPGATNLNDHEGVRNAVLSQYEKGKLVAAICAAPMVFGSLGIVK-------GRRATCYPGFEK-------------------YLD--GAEYTH------ELCTVDGNVVTGEGPAATFPYAYTLLEM--------- +--MTRVAICLPDY-----------GFDPTEAAIPFEYLTNKGWDIEIITQDGKEPQCDRMISGMLMGQPAKAAYQL--LSSSASFKNPKAWTAFSLLDYDVLILPGGHDKVKQIIENESLRVHLAKFFPLTKVCGAIWHVFLPILERI----------------------------------------------------------------------------------------------- +--APKVLIMMSDA-----------GHDPTEAVVPYTAFKEAGFQVQFATENGKAPKCDRMMEGVTLGAGVARQCKS--MLESDEARHPVSWTAFSLDEYNLVLFPGGHDKVRQIIESKEVHKLMLDYFPKTKAVGAICHGVMVLSSAK----------------------------------------------------------------------------------------------- +--KYKILIPLPSA-----------DFDPSESSIPWKILKENGYEVFFATPNGKPGSADRMLTGKWLIKKARTAYNE--MISDSHFQNPLSYKDLKPEDFEGLILPGGHAPMKEYLESKELQEFVGSFFATGKPLGAICHGVVLAARSK----------------------------------------------------------------------------------------------- +--TYKVLIPLPSV-----------DFDPSETSIPWKILKENGYEVFFATPNGRPGSADRMLTGKWLIKKARTAYNE--MISDPNFQSPISYKDLKAENFAGLILPGGHAPMKEYLESEELQKFVGSFFATGKPVGAICHGVVLAARSK----------------------------------------------------------------------------------------------- +-----------------------------------------------------------------------------------LVADTPALADLDTDSFDAVFLVGGQGPMFTFRADQAVKDLVGRFVAGGKVAAVVCHATCVLLDATT-PDGELVVAGRTWTGFANSEEAYADVG---QRIQPFWIEDEARAIGTNFIVQ-GRFRAHAVRDGNLITGQQQYSGAAAARLVI----------- +MGSKKVLIPMADY-----------GHDPTETAVAYTIFKEAGFEVQFATETGNTPKCDRMISGKLLSKDAIKKYEQQDPA----ARSPFSWSDPNIAEYDLIYFPGGHDKVRQAIDSESLQKHIVSYFPQRKVVSAVCHGVQTLSTATL-PDGKSVLHDATTTALPGAMESGIFLGDYYKTYGKGNVETIVRKTDKQYKNSLSP-APFIVEDYNYISGRFPPDTEILAKRAVELV-------- +------------------------------------------------------------------------------------MQSPLSWTSPTLDNFDVVHIPGGHDKVRQLLDSTAVQALLADYFPKRKVISAICHGPLLLCNTKG-DDGNSILYHCTTTALPAFFESSAYLGDYYKTYGAGSVEASMRKAPSQFKSSWIPHKPFVVEDYNYVSARFPPDAAKMAEMTVNLVH------- +------------------------------------------------------------------------------------MQNPLAWTSATLDDFDVVHIPGGHDSVRQLLDSASAQNLIADFFPQRKIVASICHGPLLLSNAKA-ADGKSVLYDCETTTLPSFFESFIYLGDYYKTYGADNCEESVRKVPSQLKSSWVPNQPFVVQDYNYISARFPGDAERFSEMIVNLAL------- +------------------------------------------------------------------------------------WKHALHWSTADLDAFDAVFLPGGQEKIRQLIDSPVVHKLLANYFPQGKAVGAICYGVKVLAQAKG-PDGRSILYGRTTTTLPALFEKAAFMGDYFKVYGASDVEVSVVKVPACLKSSWALAP-FVVEDFNCASGRHPGDAQLLAERLVDMIR------- +----------------------TDGFEEVELTEPLGKLQAAGADVHVISNKSGTIR-----------GWDQDHW-------NREIKVDKQLSEIRVTDYDALVLPGGQINPDVLRADPKVVSFVREFFNSKKPLAAICHAPWLLIEA-------DVVRGRDVTSYKSIRT-------------------DIVNAGGNWLD------QEVVCHEALITSRNPGDLPAFIDKIIE---------- +----------------------AHGFEEIEATYPIEYFLSRGAEVDIIAPDWIK---DRVMAVQFLKPS-------------VWLPVTKNISQAVVTDYCAVVIPGGAWNPIIMRTDQQILEFVKSAQKANKLIAAVCHGPQVLISA-------GLVKGRMITGVGDIRT-------------------DLANAGAEVVH-----DQPVVVDGNILTSRDPNDLAEFSK-------------- +-------------------------FEDSELFYPYFRLIEEGIDVDIAALNKGEIK------GE--------YF------F--KVEAKLNFSEVDPSNYKALIIPGGRA-PEAIRGNDDVKRIIKYFVDNNLTIGAICHGQQTLISA-------KVLEGKDATCYISIKD-------------------DLINAKANYK------DEKVVVCGNIVTSRCPDDLPYFAKEII----------- +----------------------ADGFEQVELTLPVKALRAKGATVEIVSLRRGRIVGMHLNVPGS----------------RTKV--DRTVEKVNAARYDGLFVPGGFIGPDLVRQSEEARDLVRAFDAAGKPIAVICHGPWVLASA-------EILKGRQLTSWPGIRD-------------------DLVHAGAVWRN------EAVVVDGNLVSSRGPQDLPAFTRAMVD---------- +-------------------------------------------------------------------------------------------NNALLNDADALILPGGMPGASNLNDSEAVKEALLGQYREGRIVAAICAAPMVLGGL-------GLLKGRKATCYPGFEPKL---------------------IGANVT------GEAVEVSDNVITGKGPGLVMNFGLALVAAI-------- +-----------------------------------------------------------------------------------------------------------MPGTKHLGECKPLVSLLQRQAAANKNIAAICAAPSVLGQA-------GLLNGYKATCYPGFEQFL---------------------TGATVT------GDNVTVDRNITTGKGPGAAISFATAIITQI-------- +-----------------------------------------------------------------------------------------------------------MPGAATLDKHEGLRRLILDFAAKNKPIAAICAAPMVLGKL-------GLLKGKKATCYPSFEQYL---------------------EGAECI------DAPVVRDGNIITGMGPGAAMEFALTIVDLL-------- +-------------------------------------------------------------------------------------------DDYQTAGEKILVIPGGVPGVDNLKANQKLSEILKAQGAGTGHLAAVCAGPTVLGNL-------GLLDGKRATVYPGFDGGL---------------------GAAKYE------DVPTVVDGQVITGRGLGAGIDFALEIVRTL-------- +-------------------------------------------------------------------------------------------SDVITDKVEMIVLPGGMPGTLNLEKSPVVQAAIKFCADNKKAIGAICAAPSIIGKL-------GLLKGKKATCFPGFEQFL---------------------EGAMFT------GDLVNIDDNIVTAKGAGAAVEFGLALGALL-------- +-------------------------------------------------------------------------------------------EEVNFVESDMIVLPGGMPGTTNLNAHEGVRRVVKDFAAEGKPIAAICAAPTVLGNL-------GLLKGKRITCYPGVETEI---------------------QGAVML------RTQVAVDGNIITSRGVGTAIAFALKLIEVL-------- +---------------------------------------------------------------------------------------------------------GGVPGATNLKESEVLESIVKKQASDGRLNAVICASPAALGSR-------GLLKGLKATCYPSFMEQL---------------------APATTV------ESRVPQDGKVVTSRGPCTTMEFAVALVEQL-------- +-----------------------------------------------------------------------------------------------------------MPGSTNLRECKVLEKMVKMHAEKGELYGAICAAPATLAHW-------GMLKGLKATCYPSFMEKF---------------------TA-IPV------NSRVVVDRNVVTSQGPGTAIEFALALVEQL-------- +----------------------------------------------------------------------------------------------------MIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAAPIALNQA-------EILKNKRYTCYDGVQEQI---------------------LDGHYV------KETVVVDGQLTTSRGPSTALAFAYELVEQL-------- +----------------------------------------------------------------------------------------------------MLVLPGGMPGTKYLAGYKPLIDLLTDFNNKGKKIAAICAAPSVFSGL-------GFLKGRKATSYPSFMEVL---------------------SKAVTS------EDSVVVDGNITTSRGLGTAVDFALSLISQL-------- +-------------------------------------------------------------------------------------------SQVNFEEYDCLVLPGGGQGTKNLEACEPLMQQIDAFYASGKYIAAICAAPSIFGHR-------GILKGKRACAYPCFEDHL---------------------EGAAVT------AGPVEVNGNVITSRGMGTSIPFGLAIAGVF-------- +-------------------------------------------------------------------------------------------EETDFSDGDMLVLPGGMPGTLNLKEHEGLRNLIGEFDKKKKYLAAICAAPSILSEL-------GILKGRKACAYPSFEEGL---------------------DCAQVV------HEAAVTDGHVTTGRGMGAAIPFALKLTELL-------- +-------------------------------------------------------------------------------------------DEADFSVADMLVLPGGMPGTLHLGEHKGLQNILKDFHNEKKNIAAICAAPSVLGKY-------GILEGRRACCYPSFEEQL---------------------TGAEVV------FEPVVQDGHIVTSRGMGTAIPFALKLTEVL-------- +-------------------------------------------------------------------------------------------SDCRDAVFDLIALPVCMPDATNLKESKVLETIVKKQASNGRLYAAVCASPAALGSW-------GLLKGLKATCYPSFMEQL---------------------APAATV------ESRVQQDGKVVTTRGPGTTMEFAVALVEQL-------- +-------------------------------------------------------------------------------------------DDSL-LDYDLVAFPGGRTGALNLRNNKKLADLMIQRNKAGKWDAAMCAAPIALGHY-------GLLEGANYTCYPGFEKQI---------------------EEGHFS------TDITVKEHKIITSRGPATAWAYAYTIARTL-------- +-------------------------------------------------------------------------------------------------KFDLLVVPGGAKGAETISQNPAVQELIRKYIDAGKYVGMICAGDLAAQ-T-------SKLPKQPLTSHPSVKAQL---------------------EGYEYS------ESPVVVSGKLVTSRGPGTAFPFALTLVELL-------- +----------------------------------------------------------------------------------------------------MVVLPRDNLGAQ--NLSAAMKEILKEQEKRKGLIAAICAGPTALLAH-------EIDFGSKVKTHPLAKDKT---------------------MNYSYS------ENRVEKDGLILTRHGPGTSFEFALAIVEAL-------- +------------------------------------------------------------------------------------------------------------MGRREMHTSATVGKILKDQEKSGRLVAAICAAPIALKSH-------GVGCGKQVTSHPSKKDEV---------------------A-YKYS------ESRVVVDGQLITSRGPGTAFEFALAIVEKL-------- +-------------------------------------------------------------------------------------------DEALRQDYDMVALPGGMPGSEHLKNDPRLAALMKTMATQGKYVAAICAAPMALHAA-------GLLEGKRATSFPGVIEEM---------------------PGHRYQ------TDAVVVDGNIVTSRGPGTAMDFALQLVELL-------- +-------------------------------------------------------------------------------------------DKVSADDFDAIILPGGYPGFVNLGDSEKVLKLVKEMHDRNKYVTAICGAPSVLAKA-------GVIQGKRATIYPGMEDTL---------------------TGAQPS------DERVVVDGRIITSRGPGTAMEFAIKLVEVL-------- +-------------------------------------------------------------------------------------------LKILQEDFDAIALPGGLGGSKAMSESSKLGEVLKSFESNGKLIAAICAAPTVLLTH-------SIALGKSLTSYPSFKDQL---------------------SGKYID------DKTVVVDGNLVTSRGPATAFDFALKLGEIL-------- +-------------------------------------------------------------------------------------------EACAGKSFDLVVCPGGMPGAEHLRDSKELVALLQKQKDDDKLYGAICAAPAVLHAH-------GLLPPGAATSYPSFEPKM---------------------TG--FK------HETVVVNGKCVTSQGPGTSMVMGVKLVELL-------- +-------------------------------------------------------------------------------------------ETCAGKSFDLIVIPGGMPGAEHLRDSNEVVALLQKQKEDGKLYGAICAAPAVLHTH-------GLLPPGAATSYPSFESKM---------------------TG--FK------LQNVVVNGKCVTSQGPGTAMAMGVKLVELL-------- +-------------------------------------------------------------------------------------------SEC-NEQYDVIAIPGGLPGADNLAGSQLLIQKIKEQLAANRFVAAICASPAVLEGN-------GIIQGRKCTAYPSFQPKL---------------------AN--AV------HQRVVVDNHLITSQAPGSAIEFSLEIIRQL-------- +-------------------------------------------------------------------------------------------DEAEKNSYDLIVLPGGLGGAEAFASSEKLVNMLKKQAESNKPYGAICASPAVFEPH-------GLLKGKKATAFPAMCSKL---------------------TD--HI------EHRVLVDGNLITSRGPGTSLEFALAIVEKF-------- +-------------------------------------------------------------------------------------------DEI-SPSVQHITLSRG---AKILADFETLKEEHDFDAVSNKLVGCICAGSLAAKTA-------GIGLGLRITSHPSVKGDL---------------------EKEYID------DERVVVDGNLVTSRGPGTAIDWALTIVQIL-------- +-------------------------------------------------------------------------------------------EAVDTKNLDAIALAGGFDGMNNLKNSNEILSIIKKLHSEGKIVSAICASPIVLNAA-------GVLEGE-FTCYPSCETGL---------------------QG---V------NKAVVVNKNVITSAGPATAILFGLELAKQL-------- +---------------------------DYETMVPFQALQMIGHQVDAVCPDKTAGDYVMTAIHDF-DG-AQTYSEKPGHRF--TL--NADFAAVKAENYDALVIPGGRRRSI-CACTRRLLKLVQAFDAARKPIAAVCHGPQLLAAA-------GILQGRTCSAYPACAP-------------------EVRLSGGHYADIG---IDQAHVDGNLVYRPRLAGSSTVA--------------- +---------------------------NMEIFAPYHCLIVLGFEVHAVCPGKSKGEKVATAVHDFVG-F-QTYTEKQGHNF--EL--NATFDEIYPSDYAGLWIPGGRA-PEYLRMNEKVLDLIRHFQEANKPIAAICHGAQLLVAL-------GGLQGRQITCYPACAV-------------------ELKLAGAQYVDAK---VEDAVVDGNIVSGVAWPSNPAVL--------------- +MTTAKVLIPMSDYG-----------HDPTETAVPYTEFKKAGFEVHFATEKGRTPECDKMLKGKVLGGLAVEAYNS--MSTQPEFQNPLSWSSFSLDTYNLVFLPGGHEKVRQLIDSHIMQRHIAAYFPSKRSVAAVCHGVMVLSKTKD-MEGKSVIHECDTTALPALFEQVAFLGDYYKTYGAANVEEAVRKVDKQYKNSI-GIGAFVIEDYNYISARFPGDAKLLAEKTVSLV-------- +--MPRALLLT----GDAAE--------ELDTMYPYYRVQEGGWDVDVSSRTMRD---VQLVIHEFDP-NSDAYVEKNGRK----LPVDVPWADVDVERYDALIIPGGRA-PEWIRVDPDVRRITEHFFARNLP-------------------------------------------------------------------------------------------------------------- +--SKKVLIVT----GDAVE--------ALEVFYPYYRCIEENIQCTIASPVKKK---LQTVVHDFLP-EMETVTEKWGYK----IESHASVDEIDPADFDGLIIPGGRA-PEYIRLNPWC--------------------------------------------------------------------------------------------------------------------------- +--AKNVLIVT----GDAVD--------CLEIYYPYYRCLEENISVTIASPTKKK---LQTVCHDFLP-EMETFTEMFGYK----IDSHASVDEINPADFDSLILPGGRA-PEYIRMNSKVQEIAAHFLTENKL-------------------------------------------------------------------------------------------------------------- +--TAKILLVT----GDAAE--------SLEVLYPYQRLREEGYEVHIAAPTRKK---LRFVVHDFED-GFDTYTEKPGYT----WPADLAFTEVDPGAYAALVVPGGRA-PEYLRNDAELRKILKAFFDADKP-------------------------------------------------------------------------------------------------------------- +--ATKILLVT----GDAAE--------SLEVFYPYQRLREEGYQVDIAAPTKKR---LQFVVHDFVD-GYDTYTEKPGYT----WPADIALADVEPADYAALVIPGGRA-PEYLRNDPHVQRIAQHFFAADKP-------------------------------------------------------------------------------------------------------------- +--SKKILMIV----GDFNE--------DLEVYFPYQAMLMNNYLIDTVSPGKNF---IQTAVHDLDKPHLQSYTEKLGHL----FPITADFSKITLKDYDALIIPGGRA-AEYQRLNKDILAITRHFHETNKP-------------------------------------------------------------------------------------------------------------- +--AKKILLLA----GDFAE--------DYEVMVPYQVLELLGYQVDVVCPGKKK---IATVLNEMAE--FQTYIELRAHN----FTLNKSFDEVKAADYSGFYIAGGRA-PEYIRLDKTVIEINQAFFXXXVQ-------------------------------------------------------------------------------------------------------------- +--AKKVLFLT----GDFAE--------DYETMVPFQALQAVGHHVDAVCPGKRK---IKTAIHDFEG--DQTYTEKPGHQ----FTLNATFDDVDASGYDALAIAGGRA-PEYLRLDAKVIALVRA--------------------------------------------------------------------------------------------------------------------- +--AKSILILC----GDYME--------NYEVMVLFQALLAYGVSVHVVFPGKKV---CQTAVHQGLG--HQTYYESRGHN----FTVNVTFDEVDASKYDGLVIPGGRA-PKYLAMNESVLDLVRKFFSSGKP-------------------------------------------------------------------------------------------------------------- +--GKQILMLV----GDFVE--------DYEAMVPFQILTMVGHDVHTVCPGKKS---VKTAIHDFDG--AQTYSEKPGHN----FALTHSFEEVDETTYDALVVPGGRS-PEYLRLNSRVIEIVQYF-------------------------------------------------------------------------------------------------------------------- +--YLKIELCE----SDYME--------DYEVKVPFQSLQALGCHVDAVCPAKKR---FPTAIHDVLRVTKL-----------------TVKKQATLLLYDDLVIPGGRA-PEYLALNKHVLNMGKEFMNSEKP-------------------------------------------------------------------------------------------------------------- +----------------------VDGFEEAELVEPQRALSAEGAQVDVISQQPGEIQGFRHV-----D-----------KGA--RVKVDHTFDDAKQGDYDAIVLPGGVVNGDAMRMIPAAREFVTAAIGADKPVAVICHGGWLLVSA-------GLVDGRTMTSWPSLQD-------------------DIRNAGGKWV------DERVVRDGNLITSRKPDDLDAFNGAL------------ +----------------------------------------------------------------------------------ESLRNTKRIESISAEDVAAVVLIGGHGCLIDFPNCEGLHKLCSNVYRSEGVLGAIAQGSVGLAYMKN-DRGEPFLKNKKITCMSNEEEKSF------KEELPFYVEEKMEQLGVKVENQ-QAFKPNVIVDQRLITAQNPQSSRQFADKLHQTI-------- +---------------------------------------------------------------------------------------------------------------------------MGHFFDANKPVGAICHAAQVLEVVR------DKLKGRTMTAYIACKP-------------------SVEGMGAKYAS------ETLYVEGNLVSGHAWPDLPGFMREFL----------- +---------------------------------------------------------------------------------------------------------------------------ARHFLDNNKPLAAICHGAQILTA-A------GGIQGRKMTCYPDVRF-------------------ELISAGGDYQKVD---SKEAVIDGNLVTGVDPTSLVEFMKAFI----------- +---------------------------------------------------------------------------------------------------------------------------IRAFFDQKKPVAAICHAPWTLIE-A------GVLKGRTLTSYPTLKV-------------------DIENAGGTWIN------EEVVVDNGLVTSRDPNDLPAFCAKLV----------- +---------------------------------------------------------------------------------------------------------------------------IDGFFGKNKPVAAICHAPWLLAE-I------NKLRDRTITSFPSIKS-------------------DLINAGANWVD------QEVCVDQGLVTSRSPADLEAFNAKFI----------- +-----------------------DGFEQAELLEPKKALEAAGATVHILSDKTDSVQ-------GFK-HVD------KG----ESVSVDGSLDTARPEDYSAVLLPGGVVAMRLLP---QARNFIRAANDAEKPIASICHGGWLLISA-------GIAKGRTVTSWPSLQD-------------------DFKNAGSQWVD------QEVVRDENFVSSRKPTDIPAFNNEFMK---------- +-----------------------DGFEQAELLEPKKALEAAGATVHIISDRKSSVQ-------GFK-HVD------KG----EVVSVDKSIDEARAEDYSAVLLPGGVVALRMLP---QARTFIRAANDAEKPIASICHGGWLLISA-------GIAKGRTVTSWPSLQD-------------------DFRNAGSQWVD------QEVVRDENFVSSRKPDDIPAFNNELLK---------- +-----------------------DGFEQAELLEPKKALEAAGATVHILSDKSDSVQ-------GFK-HVD------KG----EVVSVDGRLDAANPADYSAVLLPGGVVAMRLLP---EARNFVRAANDAEKPIASICHGGWLLISA-------GIAKGRTVTSWPSLQD-------------------DFKNAGGQWVD------QEVVRDENFVSSRKPADIAAFNNEFMK---------- +-----------------------DGFEQAELLEPKKALEAAGATVHILSDKSDSVQ-------GFK-HVD------KG----EVVSVDGSLDNASADDYSAVLLPGGVVAMRLLP---QARNFVRAANDAEKPIASICHGGWLLISA-------GIAKGRTVTSWPSLQD-------------------DFKNAGSQWVD------QEVVRDENFVSSRKPADIPAFNNEFMK---------- +----------------------THGFNLPEMVETRRALEEAGARVELVAPKPGTVRADA--PE----GQV--------SE----FRVDRALTEARPDAYHALYLPGGTHSADSLRLAAGATEFVQGFLRAKKPVAAICHGLWLLADA-------GGVKGRRVTSFPSLRR-------------------DLRNAGATWVD------EAVVEDGQLVTSRRPADLPAFTPRVV----------- +----------------------THGFNLPELTETRRALEEAGARVELIAPKTGIVRAEA--RE----GWR--------VE----FPVDRVLGDARPDAYHALYLPGGTPSADSLRLVPEAVTFVQGFLEAKKPVAAICHGLWLLSDA-------GGVKGRRVTSFPSLRL-------------------DLRNAGATWVN------EEVVVDGPLVTSRSQDDLPAFNRQVV----------- +---------------------APDGVEQVELTEPWEAVRDAGGEPVLVSTAPGKIQAFHHL-----DRA-------------DRFDVDETVDQADPAAFDALVLPGGVANPDFLRTHRDAVRFTRAFFDAGRPVAVICHGPWTLIDA-------EVVRDRRITSWPSVRT-------------------DLVNAGAHWVD------EEVVIDNTLISSRRPDDLKAFCAAIVDH--------- +---------------------APEGVEQVELTEPWQAVRDADGVAVLVSTKEGRVQAFNHL-----AEG-------------DTFAVDETVEGADPGSFDALVLPGGVANPDFLRWQPGVGAFVRSFFDAGRPVAVICHGPWTLIDA-------DVVRGRRLTSWPSLRA-------------------DLTNAGATWVD------DEVVIDNVLVSSRKPADLKAFTHALVDE--------- +-----------------------------KVNYPLLRLREAGHITFTIGPEQGKVY---SSKHGY------------------PCTADYGIDQISVDKLDGLIIPGGWC-PDYLRRNKKFVQLVADMVHSGKLVGAICHGPWMLCSA-------KCIKDRRLTCFVAIKD-------------------DVENAGGIYED------SSVVIDGNLVTSRIPSDLPDFSRAVLQVL-------- +----------------------------TKVAVPYQTFKDAGFDVNFATETGSTPRCDRMLEGKLLGAAAINLYDT--MVKSAEMQKPLSWTSLTLDDFDIVHIPGGHDKVRQLMDSTAAQKLLADYFPQKKIVSAICHGPLVLCNTKG-QDGNSVLYHCTTTALPGCFESLAYLGDYYKTYGAENVEDSMRKA------------------------------------------------- +----------------------ADGFEHVELSIPEKALRLAGADVEIVSLHPGRIRGMNMTAPT------K------------TVRVDRTIDEVSVDEYDALFVPGGFIGPDLLRQSGPARRFVAAFDAAQKPIATLCHGPWMFASA-------GIARGRTLASWPGVRD-------------------DLVHAGATWR------DEPVVRDRNWITSRGPQDLKQFVPAM------------ +-------------------------------------------------------------------------------------------------------------------------------------MAAICHGPWLLLES-------EVVRDRDVTSWPSVKT-------------------DLINAGARWQ------DAEVVVDGQLITSRMPDDIPAFAAAVAKA--------- +-------------------------YVEPEIAYYERRFAEEGARVDLLTRLGQE-----SIT--FYGHEYQAPM--------AVNGDLEAVDDERLAGYDALIVPGGMV-SDRLRYTEDAVQLLRRAFAVSILKGVICHGMWLVSPIP------EVVRDRRVTCHNNLIG-------------------DVRNMGARYTD------QDVVVDDDLITGRSAGHCHLFARTLIDLVV------- +-------------------------FFEKEIFYYEQRFAEAGVEAHFVSRLGQE-----SLT--FLGHEYRAPL--------NCTRSFEGWSDEDLASYDALIVPSGMV-ADRLRYTDDASALLERAFAL-LLKGIICHGLWLAAPVR------HVVAARRMTCHNNLLG-------------------DAAAYGVDYVD------EDVVVDGDLISARTGGHAYLLASAILAAID------- +-------------------------FVEDEIAYYRKRFAEEDIEVVLLTRLGQE-----SLT--FTGHEHQATL--------DVNGDLEQLDYGELHQFSALVVPSGMV-ADRLRYSEDAVALMRRAFRISLLKAFSCHGLSLLSAAP------ELVGDREVTCHNNLVG-------------------DVRNMGARYLD------QDIVIDRDLITSRTVEERHLLARAVIETLA------- +-------------------------YVEDEISYYRRRFGEEGAEVVLLSRLGQS-----SLT--FTGHEQRAPL--------TVSDDLEELDYARLAGYSALIVPSGHV-ADRLRYSEDALDLMRRAFRLTLVKAFSCHALWLVSAAP------DLVAGRDVTCHNNLVG-------------------DVRNMGARYTD------QDVVVDGDLVTTRTVEQCHLLARTVIDLID------- +-------------------------YVEPELHYYERRFAEEGATVRWLTRLGQD-----SLT--FTGHEFGLPV--------TVDDDLERVDDDTLAGFDALIVPSGMV-SDRLRYTEDAVDLLRRAFGMGVLKGVICHGMWLVSPIP------EHVRGRRVTAHVNLLG-------------------DVRNMGAVYTD------QDVVVDGDLVTARSADHCHLFARAIIDLVA------- +-------------------------FYEPEILYYQHRFPEEGAEVHFLSRMGQD-----EIT--FQGHEHRMPF--------VVRESFEDVDEFALKEYSAVIVPSGMV-SDRLRYTEDAVRFLRRAFQDAIVKGIICHGMWLTAPVP------HLVRGRRAVVHNNLLG-------------------DLRNMGGLYVD------EDVVVDDDLVTGRTGAHCHLFARTIIDLIA------- +-------------------------FYEHEIWYYHYRFAEEGAETHLLTRLGQQ-----SLT--FQGHEYHAPL--------DCHESFEDIDDRELNTYAAIIVPSAFV-ADRLRYTEDATGFLKQAFANNILKGIICHGMWLVAPVP------ELVRDRRVTCHNNLHG-------------------DVVNMGAIYTD------RDVVVDGDLVTGRSGAHCHLFAQKIIEILA------- +-------------------------YVEPEIDYYRLRFAEEGAQVEFLTRLGRE-----NIT--FTGHEHQLPI--------TVDGDLEQVDDERLRGYDALIVPSGMV-SDRLRYAESAVDLLRRAFAESVLKGVICHGLWLVAPIP------EVVRGRPLTCHNNLVA-------------------DVRNMGAQYVD------QDVVVSGDLVTARSADHCHLFARTVIDLLA------- +-------------------------FYEPEILYYQRRFAEEGAEVRFLTRLGNE-----RLV--FRGHEHRMPF--------EVTESFEDLDEYGLREFAAVIVPSGIV-ADRLRYTEDAVTFLRRAFADAIVKGIICHGMWLAAPIP------SVIQGRKAVVHNNLLG-------------------DLRNMGGVYVD------QDVVVDEDLVTARTGNHCHVFARTIIDQLA------- +-------------------------FYEHEIWYYNYRFAEEGADVHFLSRLGQP-----AIT--FTGHEYKAPF--------TCSESFENMSDDDLKSYDAIIVPSAMV-SDRLRYSEDAVKFIQRAFAEGILKGIICHGMWLLSPTA------ELVRGRRVTCHNNLYG-------------------DVKNMGAIYID------LDVVHDGDLITGRSGAHCHLFAKEIISLLA------- +-------------------------FYEHEIWYYHYRFAEAGLEARFVSRLGQP-----QIT--FKGHEYHAPF--------ECRDSFEDIDDQALADYGAVIVPSGMV-ADRLRYTEDAAAFLQRAFARDLLKGIICHGLWLTAAVP------GLVKGRRLTCHPNLYG-------------------DALAYGAVFVD------EDVVVDGDLVTARTGNHAHLLARALVERLG------- +-------------------------FYENEIFYYQFRFKEAGYEVHFLSRLGNE-----GIT--FSGHEFRAPF--------YCNESFEALDDEALNDYAAIIVPAGMV-SDRLRYTEDACVFLQKVFARDIVKGVICHGLWLFSPVA------ELVKGRKMTVHNNLLG-------------------DAKNYGVEYVD------ADVVVDGDLVSARTGGHCYLLAFEILKTLA------- +-------------------------FYEREIWYYSYRFPEEGADLHFLTRLGQS-----SIT--FKGHEFQAPF--------ECHESFEDMSDKELASFAAIIVPSAFV-SDRLRYTADATEFLQRAFTNKILKGLICHALWLTAPAP------ELIRGRPLTCHNNLHG-------------------DALAYGALYQD------QDIVVDGDLVTGRTGAQAGLFAHKIIELLA------- +-------------------------YFEKEIFYYQFRFLEEGAELHFLTRLGQK-----QLE--FKGHEYQVPF--------TCSESFEDISDEELSSYDAIIIPSGIV-SDRLRYTEDASDFMKRAFENNILKGIICHGMWLMSPVI------EVIEGRNVTVHNNLIS-------------------DAKNYHLNYVD------EDVVVDGDLVTGRTGGHCHLFAAKIIEMLS------- +-------------------------FFENEIFYYKFRFPEEGAEVHFLSRLGQD-----KLT--FLGHEYRAPV--------DCWETFENMSDEELRTYDAIIVPSGMV-SDRLRYTEDATEFLKRVFAEGILKGIICHGLWLVAPAT------ELVRGRKLVCHNNLIG-------------------DAKAYGAIYTN------EDVVVDGDLITGRSGGHAHLFAKKIIETLS------- +-------------------------FYEHEIWYYHYRFLEEGAELHFMTRLGQP-----SIT--FKGHEYHAPF--------ECNESFEGMDDETLKSFAAIIVPSAMV-SDRLRYTENATEFLKRAFSQSIIKGIICHGLWLVAPAP------ELVKGRPLTCHNNLHG-------------------DAIAYGAIYRD------EDVVIDGDLITGRTGAHAHLFARTIIDRLS------- +-------------------------FYEHEIWYYNYRFPEEGAELHFLSRLGQS-----YLT--FKGHEYHAPF--------ECHKSFETIDDDELKTYAAIIVPSAMV-SDRLRYTEDACEFLQRAFADNILKGIICHGMWLVSPVP------ELVKGRPVTCHNNLHG-------------------DVVNMGAIYTN------EDVVVDGDLVTGRSGGHAHLFAKKIIEILA------- +-------------------------FYEHEIWYYHYRFPEEGAEVHFMSRLGQP-----SIT--FKGHEYHAPF--------ECSESFEHIDDETLRSFAAIIVPSGIV-SDRLRYVEDATIFLKRAFAESILKGIICHGMWLVAPAR------ELVKGRSVTCHNNLHG-------------------DIESYGAIYQD------QDVVVDGDLVTGRTGAHAHLFASKIIEILG------- +-------------------------YFEKEIFYYQFRFPEAGYELHLLSRLGQN-----AIT--FTGHEYKVPL--------ECSESFEALSDELLDEFDALIVPSGIV-ADRLRYTEDACRLLERAFANRLLKGIICHGMWLMAPIA------HLVEGRKAVVHNNLLG-------------------DAKAYGIEYVD------QDVVVDGDLVTARTGMHCHLFAQKILQLLE------- +-------------------------YYEPEIFYYQHRFAEEGAEVDFLTRLGND-----SIT--FIGHEYRAPF--------TVDRSLEGLSDEELRRYAAVIVPSGMV-ADRLRYTEDATELLRRAFEETILKGIICHGMWLASSIP------GKIRGRKVVCHNNLIG-------------------DVRNMGGEYVD------EDVVVDGDLVTGRTGAHHHLFARRLIELIA------- +-------------------------FLDQEIVYYQHRFAEAGIDVDFLTRLGQP-----SLT--FTGLELGLKV--------EVDKSFENLDDDALDEYGAVIVPSGYV-ADQLLYAEKAAQLVQRLMGRHILKAAICHSLWLWTPIP------QHLNGRRVTCHNNVVG-------------------SVTNTGAVYTD------QDIVVDGDLVTARTGGMFAGLAKTVIERLA------- +-------------------------FYEPEILYYRHRFPEEGAEIHFLSRLGEP-----RQT--FTGHEHRMPF--------TVTESFEDVDEFALKEFSAVIVPSGMV-ADRLRYTEDAALFLRRAFADAIVKGIICHGMWLAAPVA------GMVRDRRAVVHNNLLG-------------------DLRNMGGVYVD------EDVVVDEDLVTARTGDHCHLFARRIIDLLA------- +-------------------------FVEEEIGYYQRRFAEEGAGVELLTRLGRP-----SLT--FTGHGHRAAL--------EVAGDLEALDYHELSQLAALLVPSGMV-ADRLRYSENALELMRRAFRMHLVKAFSSHGLLLLSRAP------DLLRERPVACHNNVAA-------------------DVRNMGAVYLN------QDVVVDRDLVTCRTVEHCHLLARTVIERLS------- +-------------------------FVETEIDYYRLRFAEAGAEVKLYTRLGNE-----SLT--FTGRELGGEV--------KVDGDLEALDYHELNTLHALIVPSGMV-SDRLRYSERAVQVMRRAFRIRLLKVFSCHGLWLMSAAP------EVMAGRTVTCHNNLVS-------------------DVRNMGAVYSD------TDVAVDRDLISTRTVEHCHLLARTVIEQLS------- +-------------------------FVEDEIAYYRRRFAEEGAEVRLLTRLGQP-----SLT--FTGHEHHAPL--------DVDGDLEGADYHELLQYSALIVPAGSV-ADRLRFSEDALELLRRAFRISLVKAFSCHGLQLLAAAP------ELIRDRPVTCHNNLAA-------------------DVRNMGGVYLN------QDLVVDRDLVTSRTADHCHLLARTVIERLS------- +-------------------------FVEDEIDYYLRRFAEEGAEVRLLTRLGQP-----RLT--FTGHEHRRAV--------EVDGDLEALDYHELLQYSALVVPGGMV-ADRLRYSEDALELLRRAFRINLVKAFCCHGLLLVSAAP------ELVRERPVACHNNLAA-------------------DVRNMGAVYLN------QDVVVDRDLVTVRTADHCHLLARTVIERLA------- +-------------------------FVEEEISYYQRRFAEEGADVVLLTRLGNP-----SLT--FTGHEQRAPL--------TVSGDLEKLDYAELSSYAALLVPSGQV-ADRLRFSEDAVEVMRRAFRLKLVKAFSCHALSLVSAAP------DLIAGRPVTCHNNLVG-------------------DVRNMGAVYTN------QDVVADGDLVTGRTVAECHLLARAVIDLLD------- +-------------------------FVEEEISYYQHRFAEEGAEVVLLTRLGNP-----SLT--FTGHEQRAPL--------TVSGDLEGLDYTELSRYSALLVPSGMV-SDRLRFSEDAIDLMRRAFRLRLLKAFSCHALSLLSAAP------ELIAGRPVTCHNNLVG-------------------DVRNMGAVYTN------QDVVADNDLVTGRTVAECHLLARAVIELLD------- +-------------------------FIPEEFDAYRYNFALLGMEVDFISRLYGDYKPWKSPV--FYGDVDPSDK--------IQLGDNMDVSQVRLEDYDAIIMSANYV-SVRLRYTEMVPRLFAQAMARDLVKGALCHGLWALTPFP------ELLSGRKVTCHTVVMA-------------------DILNCNADIQF------EKVVVDDDLVTGFSKHEVVPFIRAIANQIA------- +-----------------------------------------------MSRLGYE-----SLR--FVSDVDTVGL--------EYLDVNIDFQDVDLNSYGAVIVAAGYT-SVRLRYFEPAVRFFAQAIANQIVKGALCHGLWLLTPMP------ELLRGRKIICHEVTLA-------------------DITNAGAVYVP------SGVVVDGDLVTGRSAHDVDAFIDAIAQLII------- +-------------------------YIPYEIEAYQTRFAELGATVDLMSRLEQP-----SVR--FAADVDSVEL--------ATLEVNIDFQNVDLNEYAAVIMAANYT-SVRLRYFQPAVQFFAKAMANKIIKGLLCHGLWLLTPMP------ELLKGRRVICHEVVLA-------------------DITNAGAIYVP------PNIAIDGDMVTGRAGHDVHAFIDAIATQIK------- +-------------------------YIPEEIVAYQTKFPELGATVHLMSRLNQP-----SAR--FVSDVDEVGL--------QYLDVNMDFQNADINEYAAVIMAANYT-SVRLRYFQPAVQLFAKAMHNQIIKGFLCHGLWILTPIP------DLLKGRKVICHEVVLA-------------------DIANAGAIYTP------SGIVVDGDVVTGRSGADVDKFIEAIAHLIV------- +-------------------------FIPEEIAAYRQHFEELGATVHFMSRLGNE-----TVQ--FVSDVDEIGL--------QYLDVNIDFQSVDVNEYAAVIMAANYT-SVRLRYFQPAIQFFAQAMANKIIKGLLCHGLWLLTPMP------ELLRGRKVICHEVVLA-------------------DIANAGAVYVP------PNIVVDRDLVTGRAGHDVYAFIDAIAHQIA------- +-------------------------FIPEEIEAYQQRFSELKATVHLMSRLGQP-----SVR--FFSDEDTGAP--------RTIEVDIDFQNVDLNDYAAVIMSANYT-SVRLRFFQPAVQFYAKAMANKIVKGALCHGLWILTPMP------ELLKERRVICHEVVLA-------------------DIMNAGAIYEP------SGVVVDDDLVTGRSRHEVYPFIDAITERIQ------- +-------------------------YIAAEIEYYQREFSQLGAEVELLSYLGAK-----SRQ--LVCDIDSPEI--------HTLVVDVDVADREANNYDIVVMAANYC-SVRLREI-PAVDFFAKAMLNKIVKGALCHALWILTPIP------ALLKGRKVICHTVVLA-------------------DVHNAGAIFVP------AKVVIDDDLITGRSFADIEAYFQAIVQTAI------- +-------------------------FDETELVAFQQYFPVHGYEVVFMSYLGQP-----ELT--FNGNDHQ-----------RQVVVKTDITQVDLSQYAGVILIGGYA-MDRLRYETEALAFLRQVIATRIKIGAICHSLWLFTADP------SLLQGRKVTAAHNIAA-------------------DVRNAGGVLQV------EDTFVDGHLITGKHPAVVDVFMETFLRELD------- +-------------------------FDQTEYRLFNAHFPEYGYEVEYISHLGQP-----ALH--FGGNPDDGII--------EKVTVTTEINDINPDDYKGFICIGAYA-TDRLRYQASAVVFLRKVINNKIKLGTICHSLWLFCADS------DLIRGKKVTCAHNIIC-------------------DVENAGGDVIY------EDLVIDGNLITGKHPGVTMQFIEAFVKEIE------- +-------------------------FDQTEFHMFNDYFPKQGYEVEYITHLGQD-----SLS--FGGNPDDGDV--------AHVTVEKEVNDVSLDDYVGFICIGAYA-MDRLRYQVNAVAFLRKAMAKDLKLGTICHSLWLFCADK------DLLAGRKVTCAHNIIS-------------------DVENTGAEVIY------DDLVVDGDLISGKHPGVTQEFMEKFIEEIE------- +-------------------------FDETEYIRFNQFFPENGYEVDYMSHLNQE-----SLK--FNGNDHQ-----------AEATVSVEVNDVNLADYKGIILIGGYA-MDRLRYEPSAVNFLRKAVKANLKIGTICHSMWLFCADK------ELLKGRKVTCAHNILC-------------------DVENAGGTIVY------EATHIDGNLISGRHPGVVEEFMQLFLQELD------- +-------------------------FDETEYRRFNEFFPEVGYEVEYISNLGQD-----KLV--FNGNDHE-----------EKITVDVDFLEVKPEDYRGIILIGGYA-MDRLRYQVSGVEFLRKAVNVQLKIGTICHSLWLFCATP------ELIIGKKVTCAHNIIA-------------------DVENAGGVVMY------EATYVDGNLISGRHPGVLEDFLKVFMQEIE------- +-------------------------FDDTEFRRFNEFFPANGYEVEYLTHLHQE-----QLT--FKGNELK-----------EQVTVTVEVNDIEPRDYKGIILIGAYA-MDRLRYEANAVQFLRKAVKDQLIIGTICHSIWLFCAAP------DILKGREVTCAHNVIC-------------------DVENAGGIVMF------EIVHIDGGLVTGKHPDSIDEFLEIFLNELE------- +-------------------------FDEIEFRAFNKFFPANGYELEYISHLNQK-----ELT--FKGIDLT-----------EEVTVIVEVNDIEPTDYQGIILIGAYA-MDRLRYEEHAVKFLRKAVKTRLKIGTICHSLWLFCADP------ELLKNREVTCAHNIIC-------------------DVQNAGGIVVF------DNLHIHGNLITAKHPNVVAEFMDIFLKVIN------- +-------------------------FDQTEFRKFNEYFPQKGYQVEYVSHLGNP-----QLT--FGSNPDTGI---------DHVIVTTEVNDIHPADYKGVICIGAYA-MDRLRYQVSAVVFLRKAMDTNLKIGTICHSLWLLCADP------SLLKNRQVTCAHNIIC-------------------DVENAGAEIIY------EELVIDGNLITGKHPGMVDQFMEVFVAEME------- +-------------------------FDATEFKRFNEFFPENGYEVEYISHLGNK-----ELK--FGSNPENDI---------FHATVTTEVNDVKPSDYKGIIAIGAYA-MDRLRYQVTAVEFLRKAVAENVKLGTICHSLWLFCADP------DLLKNKKVTCAHNIIC-------------------DVENAGADVVY------DDLVIDGNLITGKHPGVVDLFLDAFLAEIE------- +-------------------------FDATEYRRFNEFFPEHGYEVEYISHLGNE-----SLK--FGSNPENDV---------FHATVSTEINDVQPSDYKGIICIGAYA-MDRLRYQVSAVEFLRKAVQEKVKLGTICHSLWLFCADP------DLLKGKKVTCAHNIIC-------------------DVENAGGDVVY------EDLVIDGNLITGKHPGVVDQFLDAFLAEIE------- +-------------------------FDGTEYRWFNEYFPAQGYEVEYISHLGQP-----ELK--FGSNPENDQ---------YHVTVTTEVNDIDPKDYKGIIAIGAYA-MDRLRYQATAVIFLRKAAATGLKLGTICHSLWLFCADP------DLLKDKKVTCAHNIIC-------------------DVENAGADVVY------EELVIDGDLITGKHPGMIEEFVKTFVEQIE------- +-------------------------FDATEYKWFNEYFPAHGYEVEYLSHLGQP-----QLT--FGSNPENDV---------FHATVTTEVNDVEPSDYKGIIAIGAYA-MDRLRYQVKAVEFLRKAMATGVKLGTICHSLWLFCADP------DLLKDRKVTCAHNIVC-------------------DVENAGADVVI------EDLVIDGNLITGKHPGMIEEFVKVFVEQLD------- +-------------------------FDSTEYRKFNEFFPEKGYEVEYITHLGQK-----ELH--FASNPENNV---------EKVTVSTEVNDIKPSDYKGIICIGAYA-MDRLRYQVNAVAFLRNAVNTNVKLGAICHSLWLFCADN------EMLKDKKVTCAHNIIC-------------------DVENAGANVIF------DELVIDGNLITAKHPGVTDEFMEKFIEAIE------- +-------------------------FDGTEFRRFNEYFPEQGYEVEYISHLGNK-----ELH--FGSNPENDQ---------YHVTVSTEVKDIDPADYKGIICIGAYA-MDRLRYEVNAVVFLRKAANTNVKLGTICHSLWLFCADP------DLIKGKKVTCAHNIIC-------------------DVENAGADVIY------EDLVIDGNLITGKHPGMVDQFMETFVKEIE------- +-------------------------FDPTEYREFNEFFPKHGYEVEYISHLGNQ-----QLT--FGSNPENDK---------YHVTVTTEVNEINPSAYKGIIAIGAYA-TDRLRYQAKAVEFLRKSMHSSLKLGTICHSLWLFCADS------DLLKGRKVTCAHNIIC-------------------DVENAGAEVVY------DDLVVDGNLITGKHPGVVNQFMEVFVKEIE------- +-------------------------FDMTEYRLFNRRFPAAGYDIQYISNLGNP-----TLQ--FGSNPDNGW---------EHLTVSKDVKDVNPSDYVGFLLIGAYA-TDRLRYTVKAVELMRKIFATGVKVGTICHSLWLLCADR------TLLEGKKVTCAHNILC-------------------DVENAGGLVQY------GGSVVDGDLITAKHPAFTDELIDIYLKEIE------- +-------------------------FDMTEYRLFNDLFPRHGYQVVYLSHLGNA-----NLT--FGSNPDNGW---------EHVLVETEINSVKADEFKGIIIIGAYA-SDRLRYQVTAVVFLRQAMAAKVKLGTICHSLWLLCADR------ALLQNRRVTCAHNIIC-------------------DVENAGAEVIY------GDLVVDGNLITGKHPGITEQFISRFLSEIE------- +-------------------------FDMTEFRLFNESFPKHGYQVVYLSHLGNP-----SLT--FGSNPDAGW---------EHVLVETEITAADPADYKGIIVIGAYA-SDRLRYQVTAVVFIRRALADHLKIGTICHSLWLLCADR------TLLQGRRVTCAHNIVC-------------------DVENAGAEVIY------GDLVIDGNLITGKHPGITDQFITTFLSEIE------- +-------------------------FDMTEYRLFNDLFPKHGYQVVYLSHLGNA-----ELT--FGSNPDNGW---------EHVVVETEINSVKPADFKGIIIIGAYA-SDRLRYQVAAVVFIRQAMATRLKIGTICHSLWLLCADR------ALLQGRKVTCAHNIIC-------------------DVENAGAEVIY------GDLVVDDDLITGKHPGITEQFIKRFLSEIE------- +--KEKILMVLPP-----------DQYQEEELNVPRDYFQSMGYQVHLASKGVKTAT-GMS-------GE---R-----------TEVDLDLDEVKLSDYIAVVFVGGEGISQELNRDPDYQKIAKSANAQKKIVGAICLGPWILADA-------GLLKGKKATASETD---------------------HIKSKGAIVS------DDAVVQDGKIITANGPSASQEFAEAVVAAL-------- +---------------------LKTGFYLNELMQPVKALLDAGHEITFATPKGTAPVDVTSIDKMYFGGDAMKASEVQLAELTSPVVSLARVEQIGYDHFDAVYVPGGHAPMQDLLMSSELGKLLTDFHENGKPTALACHGPV----------------------------------------------------------------------------------------------------- +MVKKHVLVAAA------------DGSEDIELVGVVDVLRRADIEVTVASVNASTLTLAQQT----------------------KIVADDLIGNVIKKEFDCIVIPGGLKGAENLRDSPQLLSMLKQQQYEGKWIAAICAAPSLVLQS------HGLLDGRVATCYPKFADTI-------PGYV------------APEIG----DNHDVVISKQVITSRSPGTCLQFGLAIVATV-------- +NAAKRVLVPVA------------NGSEEIELTCITDTLVRAGAEVTIASVEAGTCVMSRGL----------------------TIVADARVDALE-TDWDLVVCPGGMPGAERLRDSEALDAILRAQDARGAPLAAVCASPAVVLQP------KGLLDKRSATCYPAEPFVA-------AL--------------GAV------ADGDVVRDGHVTTSRGPGTSLAFALDLVDQL-------- +----KVLVPIA------------DGSEEIEAVTVVDVLRRAGAEVVVMSVEDDRVVCSRGV----------------------RIVADKNVRELAGSDWDLIAVPGGMPGAERIADHVKFHAVLEKHFRAGKLLAAICAAPAVCFEP------KGFLEGFAATA--HPAFVD-------EL--------------G----------GRVVVDQHVVTSRGPGTALEWALCLVEQL-------- +-MSKKVLVPIA------------DGTEEIEAVCIIDTLRRAGAEVTVASVMEGRVKASRGV----------------------GLVADALISECVEHTWDLIACPGGMPGAEHLRDCAPLVDLLKKQKAEGRIYAAVCASPAVVFEA------HGLLEGE-ATSY--PAFQG-------KL--------------SNL------AEGRVVVSNKCVTSQGPGTSLEFALKLAEVL-------- +-MSKRVLVPIA------------EGSEEIETTCITDTLTRFGAQVTVASVMSGECKMSRNV----------------------YMKADTTIEDAIEEDWDLVVLPGGMPGAEHLRDSKPLIQLLEKQKSQGKLYGAICAAPAVALAP------HGLIPDGAATCYPAPGFRD-------KL--------------KNV------SEDDVVVSGTLTTSQGPGTALLFALQLGEHL-------- +DNQKKILVPIA------------PCFEEIEAITVIDLFRRIGADIIVASILNKSVKGANGI----------------------QIICDKNLEEVIDQDFDMIVCPGGMPGAQYLSDCQILIQRLKKQKEQDKYYAAICAAPFVIFEK------HGFLNSQVGTCH--PGFAD-------KL--------------ANQTK----VNLDVVVSGKCVTSKSAGTAMDFGLQLLRLL-------- +GANVRVLVPIG------------TGSEEMEAVITIDVLRRAGAEVTVASVEDDLVVCSRQV----------------------RLVADKSIKDC--GDWDLIALPGGMPGAERLRDSAALTELVAKQKAANKLHAAICATPAVAFEP------QGVLAGKKATA--HPAFSA-------KL--------------TNQAA----VEQRVVVDGKLVTSRGPGTAFEFALALVKML-------- +SAPKKVLVPVA------------DGSEEIESVTIIDVLVRAGAAVTVASVMPSAVTCSRGV----------------------KLVADKGIDDCLGEEWDLIACPGGLPGAEHLRDSPALLTLLQRQDKAQRLVAAICASPAVVLHT------HGFLTGKRATCFPAERFVS-------SL--------------ARYED----GEEGVVEDGHVVTSRGPGTTLRFALTLVDRL-------- +MSMKNVLVAVA------------DGCEDIETVTLIDTLRRGRVDVTVASVGKSTVTLAHRT----------------------KLVADAALESVK-RTFDCIALPGGMPGATNLHDSATLAGMLKKQRAEKRWIAAICASPFVVLHQ------HGLLRGSRATCYPSFASKL-------PS--------------DVRAD----GDPDVVISSQIVTSRGPGTATSFALSVLAVL-------- +AMSKTALIVAG------------NGSEDIEFVAVCDVLHRGGVQISTASVSGNKITLSHGL----------------------KVILDDLVENVKEKSFDAIVVPGGLDGCVNCAQNLTLIEMLKKQKEDGRIYAAICAAPEMVLAA------HGILDANTAVGYPGCDTGI-------------------------PNK----GSGRVQVSGNCVTSISPGSAIEFALTLVELL-------- +MASKRALVILAK------------GAEETEMVIPVDVMRRAGIKVTVASLTGKPVQCSRHI----------------------VICPDASLEDAKKGPYDMVVLTGGYLGAHNLFNSAAMKEILKEQEKQKSLIAAIYAGPTALLTH-------EIGFGSKVTKHPLAKDKM----------------------------------------------------------------------- +MASKRALVILAK------------GAEEMETVIPVDVMRRAGIKVTVAGLAGKPVQCSRDV----------------------MICPDTSLEDAKTGPYDVVVLPGGNLGAQNLSEVKAAQSCLSEGLVRKVAASLSCVCPSVLHGC-------AVGTGETA--------------------------------------------------------------------------------- +MASKRALVILAK------------GAEEMETVIPVDVMRRAGIKVTVAGLAGKPVQCSRDV----------------------VICPDASLEDAKKGPYDVVVLPGGNLGAQNLSESAAVKDILKEQEKRKGLIAAICAGPTALLAH-------EIGFGSKVTTHPLAKDKM----------------------------------------------------------------------- +MASKRALVILAK------------GTEEMEMIIPVDVIRRAGIEVTVAGLAGKPVQCSCDD----------------------VICADASIEDGKKGPLDLVVLPGGNLGAQSLSESAVVKEILNKQENWKGLRAAICVGPTALLAE-------EIGFGSKVTTYLLAKDKM----------------------------------------------------------------------- +MATKTALFIVAE------------GSEELELVAPVDILRRANVTVTIADLADSYVKTKSNL----------------------LIKTDAKLKDVKN-KFDAVVIPGGPS-HKVLSSADVVGQILLEHEKCGKVIAAICAAPFVLFKH-------GIAKGKIIDFLSNCEE------------------------------------------------------------------------- +QNSKKALVIVTD------------GSEEIETVVSVSVLRRAQIDVTVAGITNEYAKCNRGV----------------------KIVPDQSLSNISNDIYDVIVIPGGLNAAKAISSNPEVQKLLASMHQAGKFVAAICAGTLAIKSA-------NINKGGKITSHPIVKADL----------------------------------------------------------------------- +-MSRTACIIIAN------------GIDELELGIIIDILNRADIEYFLVGLK-KEILTSTNV----------------------KIQVEKTVDDVLNDSFDVIVLPGGNIATRAMSVSEKVRTILSTQCRNKKLIAASGTFPFILSAN-------NICIGNS---------------------------------------------------------------------------------- +--MPKAIVFLAQ------------GAEEMEFSITYDVLVRGGVDVTSVYVPADLVVASRGV----------------------KLGVDTTLEALTKGDYDAYIIPGGAGGANTLSKDPTVLQILRDSHANGKIVGMICAGSLAALEA-------RVGLGGPITSHPSVKDKL----------------------------------------------------------------------- +-MTKTAILFLAE------------GTEEMEFSITYDILVRGGIQARSVYVPPNMVTASRGV----------------------KLGVDTTLADLEKGEVDALIVPGGVGGANTISKNPGVLRLLKEAYDQGKIIGMICAGSLAALEA-------KIGLNDAITSHPSVKDKL----------------------------------------------------------------------- +--MPSALILIAQ------------GTEESEYTITYDILVRASITVESALVGSAYVTCSRGV----------------------KIVPDLRLPDLA-GEYDAIIIPGGAKGAEIISHNQDVQQLISAMYGKGKIVGAICAGSLAIKSA-------GVGKDSNITSHLSVKSSL----------------------------------------------------------------------- +-----------------------DGFEEAELVEPQRALADAGAQVDVISLKPGEIQGFRHV-----D---------K----GQRVKVDRTFDDAREGDYDAVVLPGGVINGDAIRMIPAAREFVTAAVGGGKPIAAICHGGWLLVSA-------GLVEGRTMTSWPSLQD-------------------DIRNAGRQVGR------------------------------------------- +-----------------------DGFEEAELVEPLRALKAEGAQVDVISQQAGEIQGFRHV-----D---------K----GERVKVDRTFDDVREGDYDAVVLPGGVVNGDAIRMLPAAREFVTAAVGGGKPIAAICHGGWLLVSS-------GLVNGRTMTSWPSLQD-------------------DIRNAGGKWVD------------------------------------------- +-----------------------DGFEEAELVEPQRALAAEGAQVDVISQKQGEIQGFRHV-----D---------K----GERVKVDRTFDDAREGDYDAVVLPGGVINGDAIRMVPAAREFVTAAVGAGKPIAAICHGGWLLVSA-------GLVEGKTMTSWPSLQD-------------------DIRHAGGKWVD------------------------------------------- +--------------------------------------------------------------------------------------------------------------MFDLVRDAASLALIQNVAAAGKPIAAVSHGPAALLNATAP-SGVSLLAGAGVTGFSREEEDAAGMAP----ALPFQLETELERVGGGYVKADR-SGTKVVVSSPLITGQNPASAAGVAREILR---------- +-----------------------------------------------------------------------------------------KLSDVRMEDFDVVMIPGAFC-PWNMVAAGAPIEFLKKAHDAGKIIAAICHGPIAVAAA-------DLVNGKKIAGVSSCKD-------------------ALRIMGGTYNN---DW--AAAIDGQIVTARTPPEVPEFLDAITE---------- +-----------------------------------------------------------------------------------------QIFPILFDIYDVIVIPGGLN-AAKAISSNPVQKLLASMHQAGKFVAAICAGTLAIKSA-------NINKGGKITSHPIVKA-------------------DLENE-YSYQE----D--RVVVDNKVVTSRGPGTALLFALTIVE---------- +-----------------------DGFEQAELLDPKKALEEAGATVHVVSDQSESVQ-------GFQH------TEK---AL--RVSVDKALAKALPEDYAAVLLPGGVVNGDALRMSPQARGFIQSINKADKPIASICHGGWLLISA-------GIAKDRTVTSWPSLQD-------------------DFRNAGSTWLD------KEVVRDRNFVSSRKPDDIPAFNQAFISLL-------- +-----------------------DGFEEIEAMTVVDVLRRAGFEVVLAGLHGGPVESVRSVIPD------------------------ATIDAARSDQFDMVILPGGQPGAANLSADVRVIRLLNDFSKDNKLIGAICAATTVLSEA-------GLIRGKRVTAYPDYRD---------------------RLPGAQYED------SAVVIDGKIITSQGPGTAMAFALAIVSR--------- +--------------------------------------------------------------------------------------------------------------MFDLVDDATSIKLIREFHESLRTVVALCYSAAALLNVKL-ADGSRYINGEKVTGFSNKEEIAVDRQ----KDMPFHLEDALNNASGNYER------------------------------------------- +--KWKVLMIASQE-RYLLMKFFSTGNHPVEMLLPMYHLDLAGFEIDIATPSGDPVKLEMWAFPQE-DEAVKATYEK----YRSQLKQPKKLTELDGGNYLGVFIPGGHGVLNDIPFSEEVKKTL----------------------------------------------------------------------------------------------------------------------- +--ARKILIVIPIK--DF---------NDDEFSASETLFLDEGFEVVVASKGTEVGMDGTAV------------------------AVDLGVADADLSDYEAVVFIGGPGVDLELYEEPDYLSIASSARDQDVIVGAICVAPKILANA-------WLLGGRKATVFPDSESI-----AYI------------ESKGATYT------DEQVVRDGKIITACCPEASEAFAEAVVAAV-------- +--AGKILIVIPSK--DF---------NDVELSASETRFLDEGFEIVVASKVREEGMDGSSV------------------------GVDLAVADVEVSDYEAVVFIGGPGVDLELYDDPDYLNLASSAQDQGLIVGAICVAPKILANA-------ELLEGKNATVFPDSESI-----AYI------------ESKGATYS------DEEVVRDGRIITASGPEASEAFAEAVVAAV-------- +---IRVLLVIANQD-----------FFYREYFEPRRELERAGITVDVAAGRKTT-CRPHDNSGQQGSGN---------------VMPDLAIADADASDYDAIMFSGGWGSMYQYAFQAAVNRLLNDFIEQDKFVGALCHGVSVLAWAR--VNGRSLLQGKRVVASPRQSPSGTYNGRRDQPLSRWNA----QINGAQLSGNPRTSADDVMIDGKILTGEDDNSATLFGATLA----------- +---KRVLLVIANQD-----------FFYREYIEPRRQFEQAGIKVDVAAGRKTL-CRPHSNSGQRGDGS---------------VTPDLAIADANAADYDAIMFSGGWGSMYQFAFNTAVNRLLNDFVEQGKFIGALCHGVSVLAWAR--VDGKSLLHNRHVVASPRQSPSGTYNGRRDQPLSRWNA----EANRARVSGNPRTSADDVLVDGKIVTGEDDNSAKLFGATLA----------- +--KPKALIILSSARHFPVSHVISTGVFLVELAQVLKEFEN-SHEFTLCTPDGALPQDILSLPFLATSGFAPKSFARRSAEHSEILPNTLSAQTFSIGEFEFIHFPGGHAPVVDFKDSPWLGEIINTAYEENVLLSLICHAPIAMTSARWRSGGNHPFRGAKITTVPKFGELVALATNYKKTRLPYYVDEALKEAGYDVRLSLNPAAIRVEWELKLLTGNGPQSIDVQ---------------- +-------------------MPIPIGFFHVELGQVLAEFED-DYEFILATPDGQLPQDTWSLPWHATDQFTVEHYRARAREHTEPLAHTFSLPEFSFADFDFIHAPGGHAPMVDFHKNPWLGEALHLARENQVYISLICHAPIALTSTNFRENEENPFWAAEVTTVSTTGETGMLDYGYELTRLEYFVDEGLREAGFNVVAATVPTSLFLLPNLGLVTGNGPQTVDIQ---------------- +---------------MPLSTPIPIGFFHVELAQVLAEFEG-DYEFTLATPDGAPPQDVFSLPWHATDRFDIDAYRRREREHTEPLPSTLSLSEFSLADFDFIHAPGGHAPMVDFHKNAWLGEVLHTARENGVYISLICHAPIALTSTNLRADGANVFASAEVTTVGREGETGMLDQGYGPTRLEYFVDEGLREAGFTVATAPIPTSLILLSDIGLVTGNGPQTVDIQ---------------- +--ARKALVILSSAHELPLSHAISTGFFLIELAQVLKEFGD-SHEFVFCTPDGAEPQDILSLPFMATDRLAPKSFASRAAEYSQVLPNTLSARRFSLADFDFIHFPGGHAPMVDFRDSPWLGEIINLAYEQKVVLSLICHAPIAMTSAALREHGNHPFLGAKLTTVSKLGELIALTTNYKRTRLPYYLDEVLRASGYDVLVSTNPAAAQMVWELRLLTSNGPYAMDIH---------------- +--KRRALILISSARQLPLAVKISTGFFLVEMAQVLKEFEN-DYEFTFATPDGNAPQDIMALSVQSIEKFDVNRFRQREQEHSELLPNSHSLQEFTFADFDFIHTPGGHAPMVDFRDNPWLGEALHIARENGVIISLICHAPVAVTSTRQRAQGHNPFLAAAISTVPTIGELFALRFLYKKTRLSYFVDKVIKEAGFKLATSLNIAAPLLAYEVRLLTGNGPQAIDQQ---------------- +------------------------------------------------------------------------------------FQNPISYKNLKAENFAGLILPGGHAPMKEYLESEELQKFVGSFFATGKPVGAICHGVVLAARSKLPGTDRSILYGKKLRP------------------------------------------------------------------------------- +--DKKILFIC----GDYME--------DYEVKDHFQSLQALGSHVDAVCPSKKAGDTCPTAK--------------PGHT----FALTATFDDVDPSGYDALVIPGGQA-PEYLALNESVIAL-------------------ILSAA-------GVLKGRKCSAYPAVKL-------------------NVVLSGAAWLEP-ESI-SRCFTDGNLVTGAAWPGHPE----------------- +--EKRILFLC----GDYME--------DYEVTVPFQSLQALGCHVDAVCPKKKSGDTCPTAK--------------PGHD----FTLTADFEGLDASSYDALVIPGGRA-PEYLALDGKVIALVKDFMEAKKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKL-------------------NVVLAGATWLEP-DPI-DRCFTDGNLVTGAAWPGHPE----------------- +--EKRILFLC----GDYKE--------DYEVYVPFQTLQALGCHVDAVFPKKKSGDTCPTAK--------------PGHD----FTLTADFEGLDASSYDALVIPGGRA-PEYLALDGRVIALVKDFMEAKKPVASICHGQQILAAA-------GVLKGKKCTAYPAVKL-------------------DVVLAGATWLEP-YPI-DRCFTDGNLVTGAAWPGHPE----------------- +--NKRILFLC----GDYME--------DYEVMVPFQSLQALGCHVDAVCPDKGAGEKCPTAK--------------PGHD----FALTASFDNVDASSYDALVIPGGRA-PEYLALNDKVISLVKGFMDKAKPVASICHGQQILSAA-------GVLQGRKCTAYPAVKL-------------------NVVLGGATWLEP-NPI-DRCFTDGNLVTGAAWPGHPE----------------- +--DKKILFVLSSKAKLEGQSPRPAGLWAQSLAAPYEILTKQ----DFATPYTKE----------F----------KKDPKAQALLAHTSRLSEVKATDYDAICYTSSYGMFYDLIDNADSIRLLTAFERAKKPIGLTSQGPLVLKNVTDT-QGNPVVKGRTYRTAELPEDQFLKK-LKLVGTVPFLSETLVKSQGAEYKS-RKNWEPLVVEDGLLLTAQNPDSVELWSKALIQI--------- +-----------------------DGSEEIEAITLADVLTRGGIQVTLATVGNKSNNVVTMS-RG------------------VKVQGDVAIEECAGKSFDVVVCPGGMPGAEHLRDSKEVVALLQKQKEDGKLYGAICAAPAVVLHA------HGLLPPGAATCYPSFESMM-------------------T--GVDYK------HETVVVNGNCVTSQGPGTAMAMGVKLVELL-------- +-----------------------HDSEEIEAVCIVDTLRRAGAEVMVASVEDN--KLVRMS-RG------------------VCVQADKLIEV-QNEVFDCIAVPGGMPGAERCRDSAILTKMLKAHKEQGKFIAAICASPAVVFQT------HGLLEGEKAVAYPCFMDKF-------------------P--ANVRG------EGRVCVSNKIVTSVGPSSAIEFALKLVEVL-------- +-----------------------HDSEEIEAVSIIDTLRRAGAEVVVASVEDT--EIVRMS-RG------------------VCVKADKLIAV-ENETYDCIAIPGGMPGAERCRDSAALTAMLKTHKAQGKLIAAICASPAVVLQT------HGLLQGEKAVAYPCFMDQF-------------------P--ADMRG------EGRVCVSNKIVTSVGPSSAIEFALKLIEVL-------- +-----------------------NGSEEIETVTITDVLTRSDIHVTLVKVLDEKEKICVMS-RG------------------LKLIADDILDNFQNRDFDMIVLPGGGLGAQNFAKSQILIDFLRNHAHHNRYIAAICASPAVVLKE------HGFIGDKQATCYPGFINTM-------------------T--LDNYV------DEKVVVSGKLITSQGPATSMEFALKLVKIL-------- +-----------------------NGSEDVETVTVIDILRRGGIPLTVAKVFESSG-----------------------------QVADKKLTDVLNDNFDMIILPGGGKGADTFSKSKDLKLMLMRQHEQNKLIAAICASPAQVLVP------FGILKSQNATCYPSMQNQL-------------------K--NQKHI------NDLVVMDHNLITSQGPGTAAQFAFKCLEML-------- +-----------------------DGTEDIELITLVDVLRRAGVSVVLASVGDS--VNLVLA-HG------------------TKLTADDKVVNLTQKTFDLIAVPGGLVGATNCANNVTLIRMLKEQKSNGRLYAAICASPALVFGD------CGLLDDKSAVAFPGFENKL-------------------P--LV--G------TGRVHVSNRYVTSQGPGTALEFALKLVELL-------- +-----------------------NGAEDIEFASPVDVLRRAGVKVVVASLGEG--LIVKTA-QG------------------LRIEGDMPLDVSPDAHYDVIVLPGGLKGAENCRDSAHLASLLKQQHAAGRWIAAICASPALVLTH------HGLLENINSVAYPSFMSHI-------------------K----HKG------EGRVCVDKHYITSIGPGSAMEFSLEIVKRL-------- +----------------------------------------------------------------------------------------TLVKDEKASDYEAAFLAGGYGGSKNFGASEDLKKFLHELRSQNKTYGAICAAPVLSLAPL------GMLEVTKATCYPGMENMF-------------------P-AHVTAS------TDVVVKSGHCLTSRGPGTTLFFGLAIAAL--------- +----------------------------------------------------------------------------------------ASLEDAKEGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAGPTALL-AH------EIGFGSKVTTHPLAKDKM-------------------MNGHYTYS------ENRVEKDGLILTSRGPGTSFEFALAIVEA--------- +----------------------------------------------------------------------------------------------AGGPYDVVVLPGGNLGAQNLSESAAVKEILKEQENRKGLIAAICAAPFIIL-SL------ARGCVVTLLPKPISKNKK-------------------ISGHYTYS------ENRVEKDGLILTSRGPGTSFEFALAIVEA--------- +----------------------------------------------------------------------------------------------GQGNYDVVVLPGGLAGNKALMESCDVGELLRQQESQGGLIAAICAAPTALA-KH------GIGKGKALTSHPDMKRQL-------------------E-EKYCYI------EQSVVQDGNLITSRGPGTSFDFALKIVEQ--------- +----------------------------------------------------------------------------------------SSLEDAKQGPYDVVLLPGGLLGAQNLSESPAVKEVLKDQEGRKGLIAAICAGPTALL-AH------GIAYGSTVTTHPGAKDKM-------------------MADHYKYS------EARVQKDSNVITSRGPGTSFEFA--------------- +----------------------------------------------------------------------------------------VQSLDPAQ-LPDLIVLPGGAPGAKTFEESDAVARLIDRARKEGVYIGAICAATKALV-RF------GAEGKARVTSHPSVQEAV-------------------VKAGWEYA------QDKVVLDGKVITSRGPGTSLLFALTLVET--------- +----------------------------------------------------------------------------------------APLVEVADGDFDILVLPGGIKGAEYFRDSPLLVETVRQFHLSGRIVAAICAAAATVLVPH------NLFPIGNMTGFPALKEQI-------------------PAE--QWQ------DKRVVWDVKLLTSQGPGTSIDFALKMIDL--------- +----------------------------------------------------------------------------------------KALFEVADNKFDVVILPGGLQGANSLAASDEVGTILRTQYESGRYIAAICAAPIALK-SH------GIAPGILLTSHPSVKPKL-------------------VESGYKYS------EDRVVTTDHIVTSRG----------------------- +----------------------------------------------------------------------------------------TSLEEAATSPYDAVILPGGLKGSELLSESPLVGQILKQHENGGQIIAAICAAPIAFK-SH------SIALGKQITSYPIMKERL-------------------V-ENYKYV------DERVMVDGNVTTSQGPGTAFEFALSLVKX--------- +--MAKVYEFL------------ANGFEDIEALAPVDILRRGGVEIKTVSITGNEW-----VETS----------------HGITLKADLKFEDIDSEDADMLLLPGGMPGSANLNAHDGLKKVLLAQNAAGKRIGAICAAPLIL-GG------LGILKGKKAT-------------------------------------------------------------------------------- +--TKQALVFM------------APGFEEMELTITVDVLRRAGIEVHTVTLAK-AP-----VKGS----------------RGICILPDLSIDEISLENCDIAILPGGIEGTRNLGASTRVIGFLQKMHAAGKKVAAICAAPA----------------------------------------------------------------------------------------------------- +----------------------------MEAITIVDALRRANADVIVASVEDGFD-----VTAR----------------YGTRIVADVMLDEAADAPFDLIIVPGGLPGAKTLGRCEQLVTLLKKHAEANKPYGAIGAATAHVLEP------HGLLKDAAGQ-------------------------------------------------------------------------------- +--SKRVLIPV------------ADGSEDLETVTLIDVLRRAEFDVVVASAEERRM-----LTCA----------------RGTRVTADAMLLDVLAQDFDLIVLPGGMPGAKTLGELEPLAERLRRQAAGGHAFAAICAAPPMACMP------TACS----RG-------------------------------------------------------------------------------- +-----------------------MGTEEMEAVILAGVLRRAGADVTPSSVEDGLE-----VEAS----------------CGSRIVADTHIAACADQVFDLVALPGGMPGSVRLRDSEVLQRITVRQAEEKRLYGAICAAPAVVLMP------WGLHKRKKIT-------------------------------------------------------------------------------- +--MKKVAVLL------------APGFEEAEAIVTLDILRRLHIDVETLACAESRA-----VVSY----------------HDIPMVADSTLSERQQALFDAVVLPGGPQGSANLAANPAVIAFVARHDAAGKLICPICSAAN----------------------------------------------------------------------------------------------------- +--MKKAAVLL------------APGFEEGEAIVTIDILRRLNIAVETLACADSRA-----VVSY----------------HSIPLVADARLTERAEETYDAIILPGGPQGSVRLAADAQVIAAHLAHLII---YI------------------------------------------------------------------------------------------------------------ +--MKQVAVLL------------ADGFEEGEAVVFIDIMRRLDIHVDVLSCMDSLV-----LNTY----------------FETKISADFLLTEKLTHSYDAIMMPGGPKGTDRLCANEQVIQFIKRHIAEDKYICALCSSGAKVLAA------HHLLEGRHYS-------------------------------------------------------------------------------- +--TIKVAVCI------------APGTEEMEAINTIDILLRAGFDVTIASVAGALI-----MEGS----------------RGIKLVADVPLVNVADEPFDCVVLPGGLAGSECFRDSPLLVEFVNQHKYDGKLVAAICAAPAVVLEH------HQMYPQAS---------------------------------------------------------------------------------- +--SVSALVCL------------APGSEETEAVTTIDILVRAGINVTTASVAGALE-----IVCS----------------RGVRLLADTRLVDVADQKFDVVVLPGGIKGAECFRDSPLLVATVEQTHKEGRLVAAICASPL----------------------------------------------------------------------------------------------------- +----------------------APGTEEMEAVTVIDLMVRAGYDVTVASAAGALT-----MKAS----------------RGVTLTADCKLVDIADDEFDAIVLSGGVGGAETFRDSTVMIEILKQHMYESKLVAAICAAPALVLQH------HNLYPDALMT-------------------------------------------------------------------------------- +--SASALVCL------------APGSEETEAVTTIDLLVRGGIKVTTASVAGNLA-----ITCS----------------RGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVP------HDIFPIGNMT-------------------------------------------------------------------------------- +--SKKVLVPI------------ATGTEEMEAVTIIDMMVRAGYEVVVASAEGGLT-----MKAS----------------RGVTLTADCRLVDIADDEFDAVILPGGVGGSEAFRDSTVLVEIVRQQMYEGKLVAAICAAPALVLAH------HNLYPDALMT-------------------------------------------------------------------------------- +---MRALIPV------------ATGNEDIELVSLSDVLTRGGIDVILASVEEERR-----VRLM----------------QGLCIETDCLLADVADEDFDAIVMAGGIPGAMRLSEAAGLRELLIRHHTAGAVVAAICLSPALVLEP------AGVLEQCPHV-------------------------------------------------------------------------------- +--MKKVLLLL------------ANGFEAVEASVFTDVLGWGATEVITVGLR--NQ-----LTCT----------------WNFTVMPEKTVNDIQLDEFDALAIPGGFEEAGFYEDAAPFLQVIQHFYSNQKPIASICVAS-LALGK------SGILKGKKDD-------------------------------------------------------------------------------- +--MRKVLLVL------------VPGVESMEFSPFLDIFGWKDLHLEICSLE--ER-----ISAS----------------WNLKLQSELNIKDIELSEYSAVILPGGFGKYHYFEAIKDFQSLIAGALEQQLYIIGICTGS-ILLAS------TGYFEGKKMT-------------------------------------------------------------------------------- +--------------------------------------VSNGCHVDTVCPKKKSGDTCPIAIHDFE-G-DQSYNEKPGHDF----TLTADFEGLDASSYDALVIPRGRA-PEYLALDGKVIALVKDFMEAKKPVASIYHGQQILVAA-------GVLKGKKCTAYPAVKL-------------------DVVLAGATWLEP-DPID-RCFTDGNLVTRAAWP--------------------- +----------------------ANGFNEIEFTEPQKRLIEAGATTKVVSRANGLVN--GWYEDSW------------GHF----FPVDVDLAETLSVDYDGLIIPGGMHAIDKMINDPHSRRILKAFIRASMPTIIVGDAAKMLARK-------EIIQGRTVTSSINVRA-------------------ELEANGAIWKD------APFIVEDALVTVNGIEGIR------------------ +----------------------ANGFNEIEFTEPQKSLIEAGATTKVVSRANGLVN--GWYEDSW------------GHF----FPVDVDLAETLSVDYDGLIIPGGMHAIDKMIDDPHSQRILKAFMRASMPTIIVGDAGRLLART-------EIVHGLTVTSSVNVRE-------------------ELEANGAIWKA------APFVVEDALVTVNGIEGVR------------------ +----------------------ANGFDEIEFTEPQKKLIEAGATTKVVSRANGLVN--GWYEGSW------------GHF----FPVDVDLAETLAVDFDGLVVPGGIRAVEKLAEEAHSKRVLKAFMRAGMPVAVTGDAGKLLVVT-------EDAKGRTVTSSEEARA-------------------DLEAAGASWEA------GPVVVEGNLVTANGVEGVR------------------ +----------------------ANGFEEVEMTEAQRALLRAGAAPKIISPEQGLVN--GWHGTSW------------GHY----FPTDKQIGEVLAADFDLLVLPGGERSVAKLAANPHTRRIIGSFMDAGKGVAAINHGVQLLAVA-------QRLKGRTVTGNEAIRE-------------------TVEAAGATWVA------EEMNIDRQLLTARGPEEVV------------------ +--------------------------------------------------------------------------------------------------------------------------------KQNKFIISLCHGPAAFLAVGD----DPLFAGYKIVAFPDEMDAQTPSIGYMPGHLTWKFGEQLQAIGFELLNT--GISGQVFQDRKMLTGDSPLAGNALGQLAAKA--------- +--------------------------------------------------------------------------------------------------------------------------------KNDRFVISLCHGPAAFLALRHG---DNPLNGYSICAFPDAADKQTPEIGYMPGHLTWYFGEELKKMGMNIIND--DITGRVHKDRKVLTGDSPFAANALGKLAAQE--------- +--------------------------------------------------------------------------------------------------------------------------------RNDLFTITLCHGPAALLATTLD---EQLYEGYKLAVFPDSVDEMTPKVGYLPGKMPSSVSGKLEGLGMTLMNT--KSDNTVCRDRLLLTGASPLAANELGKLAAKT--------- +--------------------------------------ASTAFNLQVATPGGKAID-FVDITES-NARWVQ-DFR------LKAYASPAKLESIDGARYHALLVPSCPGALTDLANSGSLARILQHFHAEHKPICAVGHGVAALCCATN-EDGSWVFHGCSLTGPSVYELVRAPG----FARLPLVVEDFVKDSGASFSAS-EPDAVHVVLDRHLVTGQNANSTVPAVQ-------------- +--------------------------------------ASAAFNLQVATPGGKAMD-FVDVTEN-NARWVQ-DFR------LKAYASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFRSESKPICAIGHGVAALCCATN-EDRSWVFQGYSLTGPSVYELIRAPD----FACLPLVVEDFVKDSGAGFSAS-EPDAVHVVLDRHLVTGQNTNSTVPAVQ-------------- +------------------------------------------------------------------------------------------LRDLKVADYDAILFIGGPGAA-NYMDDETCHQIAREAVKADRVLGAICIASAILAKA-------GVLDGKKATVWSSPLDRSTV--------------KILEENGAIFQK------DSVVVDGKIVTGNGPGAAKEFGEKIV----------- +------------------------------------------------------------------------------------------IQEIDLDEIDSVLLPGCMDIM-LLKDEEEIFHFLEAAADKVSVIAAISSSPYLLARA-------GLLKGKRYTVGLAEEARESS--------------GIFE--KENYSD------ELVVQDGKVLTARGRGF-IEFGTHLG----------- +------------------------------------------------------------------------------------------LSEVDVDEFDSLLLPGCLDIG-ALVNHYALIHFIKEISERENWIASISSSPYLLALA-------GALQGKEYRICLPQSFIQSS--------------EHLD--AQLYRD------VPVVQDNHIITAIGSGF-IEFGIRFG----------- +EKQLNILLYLPQA------------MADWEVGLLTAELNEGVQVQVTTTAAEGPVQ---TMG-GL------------------SFLPQKALAEVDEACLDALILPGGE--SWADPAANEVLALAARLSGRSVLVAGICGATEALAAT-------GLLDNVQHTG--DSRELMA---SI-DGY-----------RGPNYLD------ELVVADSRLVTAGSWA-PIEFAAAVLAE--------- +---MTVAVALQPG------------WADWEAGPVLAALRYYGVQIEIATPDGEPQT---SIG-GV------------------LAAADYRFADPALADADVLLLIGSD--AWTTYDDP-LFSLLRQTQADGKIVGAICAGTVAAARA-------GLLAGKAHTS--NDRDWLV---KVAPGY-----------AGEGYVD------SKAVTDGKLVTASGLA-PVTFSAAIARL--------- +---MTVAVALQPG------------WADWEAGPVLALLRHLGVQIEVATPDGEPQT---SIG-GL------------------LAAADYRFDDPVLSDADVFLLIGSE--AWTGFDDE-VFGLLRQAVADGKIVGAICAGTVAAARA-------RLFDGRDHTS--NGKDWLG---EQAPGY-----------GGTRYVD------QRAVTSGRIVSAAGIA-PVSFAAGIARL--------- +-----MGLVLIEA------------FADWEYGLVAASAVWFGFSLTVLTPGGRPVT---SMA-GV------------------TVSGGTALEAAQADEFDAVILIGSD--RWEKGAAP-ADALARAVHESGGTVGAICGGTVALARC-------GMLEDRAHTS--NDRKWLR---DVAGDY-----------AGEHYRD------TAAVTDDRIVTAPGTA-PATFAVAVMKS--------- +-MGKHIAFIVIDN------------FADWEHAQLSAAARYFDGATSFHTPGGRPVT---SMG-GM------------------TINPGSAIEDLTPDAYDALVVVGSD--GWTGDDAP-IAPVLRAADEAGKVVGAICAGTVAAARA-------GLLDSRRHTS--NALDFMR---HYSPGY-----------RADLYVD------TAAVRDGTLVTAAGSA-PVTFTIEVLGA--------- +PASKTIGFIFIDG------------FADWEYGLLSASAVWFGGRAVSLSPDGAPRK---SMS-GF------------------HLTPDRGFDIAENADLDAIAVIGSD--HWASNAHP-PSPLLKAVAARGGVVGGICAGTLALARS-------GLFEAARHTS--NGRDWIL---MHEPAY-----------AGGNYQD------VHAVADGRIVSAPGSA-PGTFALAFMKA--------- +--MHPIMVILTES------------YSDWEIAALTGAGRFFNADITFCSPTGGALR---SAA-GL------------------PIVDTARF---QLQQGGVVVVTGGP--ALEGGSAP-IGEALRQSLANGAVVAGICGGTIALARA-------GLLDDVAHTS--NGPGYLE---QHAPGY-----------AGSCYVD------QPALRDVNIITAPAPS-PASFAYEVLVA--------- +--MARVGLILTPG------------FADWEYAFIAGTASFYGIDVRFFASATGQFR---SQG-GL------------------AVTVDSSLQQCLDWKPDVVVVIGGM--VWERAEAP-IRDFLHASRSSGATIAGICGGTLALARA-------GLLDTVPHTS--NSAEFLQ---QNAAGY-----------EGTLYRS------SVAVVADRIITAPGPA-PVSFTCAVFEG--------- +--MQKVAVLLAEG------------FADWEYALIGGTGGFYGLEIQYVTLGAAQLT---SQG-GM------------------QVRVAKTRADMAEMQPGVIVVIGGM--IWETDRAP-ITDMLRQHHQSGGTVAGICGGTLALARA-------GLLDDHAHTS--NDAAFLP---AHAPGY-----------KGGRYQA------QAAIQDGRVITAPGTA-PVSFTAEVFRT--------- +--MANIAVVMVDG------------VADWEIGVVLPAARWFGDQVAIASIDGQPVQ---SIG-GL------------------RITPDFALSDLAPLDADLWILPGSE--RWQAGEIPGLSGLLVERVQHQRPVAAICGATIALAYA-------GLLDQRAHTS--NALAFLQ---EHVVPY-----------AGAQYRH------EKVVTADSVITAPGTS-PVGFALACMRL--------- +--MANIAVVMVDG------------VADWEIGVVLPAARWFGDQVAIASIDGQPLQ---SIG-GV------------------RITPEFALSDLAPLQADLWILPGSE--RWQAGEIPGLSGLLVERVQQQRPVAAICGATLAFAYA-------GLLDERAHTS--NALAFLQ---EHVVPY-----------AGAHYRH------EKVVSADGVITAPGTS-PVNFALACMRQ--------- +-MSKTIAFVMIDR------------PADWEYGPLAGAAHWLGVDVVTASIDGTPLT---TMG-GL------------------TLQPHTRLAELDPLAADLWVVPGSA--LWDEAPAPPIVAALRTRAAAGRAIAGICGGTRGLAAA-------GLLDERAHTS--NEPGYLD---E-VAGY-----------RGAHYRD------AACVSDGTIVTAPGSS-PISFAEACLRI--------- +--MTRLAIVLTEG------------FADWEVAPLTASARYFNFDVVTATPEGAEVR---SMG-GL------------------RVSPDTALEHLHAHAFDALILCGGT--IWETEKAP-LAPVVEDFLAHGKIVGAICGATLALARA-------GALNKAAHTS--NAADFIA---G-VPGY-----------SGAHYKE------GYAVRGGKIITAAGSA-PVTFAAEVYRA--------- +--MTRIAIALAQD------------FADWEPALLAAAARYLGVEIVYATPDGRPVT---SMG-GL------------------KVTPDTSYDALDAVDIDALVIPGGL--SWEKGTAA-LGELVRRFREKNRLVAGICAAASALAGT-------GVLNAVAHTG--NSLASHR---A-YSAY-----------GGTLYRD------QKAVNDGGIITAAGSA-PVSFAVEILKS--------- +--MKRAITVITDN------------FSDWETALINSTCRYYGFDVRFAAPQGAPVI---SSS-GM------------------LVTPQLPIEAILLDEIDLLIICGGT--AWQTEHAP-ISGLVADAHRKNIVVAGICDGTRVLAQA-------GVLDNCRHTS--NSAENLS----SVSGY-----------RGACYQD------VYAVADQRVVTAPGSA-PVSFMTEILAM--------- +--MTTFVTILTPG------------YADWETALLNAAARYYGINTLFATPDGEEVV---SSG-GL------------------KVTPHMAVADINVDEIDALLVNGGT--IWSTPCAP-IAEVLRKAHAAGKTVGGICDGTLALARA-------GLLDEVAHTS--NGPESLP----DT-GY-----------KGEHYRD------QQAVLSGKIVTAPGTA-PVSFMGAVFES--------- +--MARIAFVVIPP------------FADWEPALLAAGARDFRDQVSWWSPGGRPVP---SIG-GM------------------TIQVDGAVEDFSPEQADALVLIGSS--TWMTPESP-LTPLLRRSVEAGLVVAGICGATLALARA-------GLLEGRAHTS--NDLAFLQ---KHAPNY-----------QGAHYRD------VQAVRDGRIITASGAA-PTTFATEVLGA--------- +--MTRIAIALTED------------FADWECALLMAVARYLGVEIRTASPDGRPVT---SMG-GL------------------KITPDLAHDAVDAETFDALIIPGGL--SWEKGTAP-FGAKVREFHGSGKVVGGICAAASALAAT-------GILNDVAHTG--NRLASHQ---K-YPAY-----------QGALYRD------QQAVSDGKVITAPGNS-PITFTMEILKA--------- +--MTRIAIALTPH------------FADWECALLMAVARYLQADVVTASPDGDAVV---SMG-GM------------------RITSDLAYDVLDPAVFDALVIPGGL--AWETEEAP-FTAHVQAFHAAGKVVAGICAAASVLAAT-------GILNSVAHTG--NSLASHK---R-QAAY-----------RGALYRD------QQAVSHAGVVTAPGSA-PVTFTIEILKA--------- +--MTTIVTLITEG------------FADWETAMLNAVARFYGVEMRFASPGGAAVT---SMG-GM------------------RVTPDLAMEAIDIGALDALVISGGT--IWQQPGAP-VSGLVHRVHEAGKVVAGICDGTLALART-------GLLDGVAHTS--NGVGYLA----PS-GY-----------AGAHYRD------VGAVRDSRIITASAVA-PVAFMEAVLEE--------- +-MAKRLAIVLTEG------------YADWECGLLMATARDCGAETVILTPGGADVT---SLG-GV------------------SIKSAGRAEDAAPADFDVLVLCGGT--IWQSGEAP-LSAPVARFVSAGKPVAGICDATLALGRL-------GLLDDRAHTG--NYRGQLP---DVVPAY-----------RGALYRD------QQAVRDRAVITASGAA-PVSFAREILDA--------- +---MRLAIVLCEG------------FADWECALLMAAARHLGVDIEVATVDGARVT---SMG-GL------------------DVSAHLSVDALDPAGFDGLVICGGA--IWDTNEAP-LSSTIRAFDRNKRVVAAICGGVHALATC-------GLLDRVDHTG--NSAESLA----ALTGY-----------HGSHYRD------QQAMRSGHVVTAAGTA-PISFSGEILHG--------- +--MSKVAVLLTQG------------FADWEYGVLCGLGQYFGLDIRYVTPTPGDVA---SMG-GL------------------VARVSDGFELLDIWEPDALVVVGGT--LWEQPEAP-ISGVLEGMHARGAVVAGICGGTLALARA-------GLLNSVHHTS--NDVGFLG---IHAEGY-----------AGAQYVD------QTALSDGGMITAPGTA-PVSFAAEIMEA--------- +SVAKKMAIVLASG------------FADWEYALIAGVGGFYGLEVAFFAPQVGTFR---SQG-GL------------------TVEVEKSVAELADWRPEVLVVVGGT--QWETERAP-ISALLNEQFQRGATLAGICGGTLALARA-------GLLNGRAHTS--NDAGFLT---RHAEGY-----------TGRHFVA------SAAVVDDRVITAPGSA-PVSFTAAVFSA--------- +--MKKAVFFLLDE------------YAEWESAFLASRLASKQWSVATASLERGACK---SMG-GF------------------TTVVDYSLMDI--GDTALLVLVGGN--GWGLE-SPELRDRVAACLATGVVVAAICGAVDFLARN-------GLLNDYRHTG--NAQHLWA---EY-PEY-----------RHAGFIA------AQTVRDRNLITANGTA-AMEFSESVLKS--------- +--MKKAIFLLLDE------------YADWEGSYLASALNSDTWEVMTASIQD-EVR---SMG-GL------------------TTLIDVQLEAV---AYDLLVLIGGK--SWHID-NQILNHFVQQAFEQHKPIAAICGAVDYLARQ-------GHLNTYRHTG--NAVQLLD---QY-ENY-----------QPYPFIA------TQVVRDKHLVTANGTA-AIPFTAAVQQL--------- +--MKKALIVLTEA------------YADWEVSYVAAELASHGFKIDTISLGESTVT---SIG-QL------------------KTIVDYTIDDI--EPYDALIIIGGN--NWSQIENEQLVQLIKTSLDNNIVVGAICAAVDFFARN-------GLLTGYKHTG--NDLNQWTTEKNY-KAY-----------TNLDFMN------EDSVVDKNLVTANGSS-AVDFAFNVIRA--------- +ANDKNILIYLPDE------------YADWEGAYLMSEL-QNKIPFTVVSETKNTIT---SIG-SL------------------KVQPQAAVSDYTADQVSALILIGGE--NWPNMDRNDVRALAAQVLKQNSVLAAICGATFALAQE-------GLLKDRKHTS--NDLNMLK---AFVPTY-----------TEANYQN------QLAVTDGNLITASGAG-PVDFTLELLRA--------- +-MPKTLVFYVQDG------------FADWEAAYILPLL-ERGIGVRVVSENGASVT---SAG-GL------------------GVVAQTRLRNVYPADIDGLILPGGD--FWMDDSANPVLAFAQDLLAQGKMVAAICAATVALGRQ-------GLLDQRRHTS--NDLGVLK---QEAPAY-----------RGSLYVQ------SLAVTDGNLITASGIG-ALEFAREIADY--------- +NRMKNAVVVLLNN------------YADWEAGYLTGILNRKDWQVKVASNQK-TIT---SIG-GV------------------VTEPDQAVAEARDSKIDLLILIGGK--SWTLE-DSNLKKLIKDQLDNQLPLAAICGSVDFLAKN-------GFLNNYQHTG--NAQYLWR---DF-PEY-----------QNAGFLK------KQAVRDRNLVTANGTA-ALDFTELTLGL--------- +--MKTVLILLLND------------YADWEVAYISSTINSGEWTVKTISTQK-EVK---SIG-GL------------------TTKIDYLLEEI--SQYDLLILIGGN--SWTND-DSDIINLVNHTLNNNIILGAICGSVDFMARN-------GLLNNFKHTG--NDLSLWN---TF-DQY-----------SNDEFQF------KQAVRDKNLVTANGTA-PIEFEQLILES--------- +YYMKKALFLLLDE------------FADWEIAHLSSIINSDRWITKIVSVTN-KVK---SIG-GM------------------TLLVDSKISNE--HDFDVLILIGGN--KWNIE-DKTLLNFIEKTFELEKPVGAICGAVDYLAKN-------GFLNKYRHTG--NSIYLWN---KL-KKY-----------ENNGFVE------TQAITDSNLVTANGTG-ELEFTEEVLRL--------- +AGLKIAIFFILNE------------YADWEGAYLASELNSSDWKVKTASINS-EVI---SIG-GF------------------KTIVDYHIPEI--AKIDLLVLIGGN--SWSIK-NDHLRKLIAKQLRSKRPVAAICGAVDFLAQN-------GLLTHYKHTG--NAQYLWK---NY-SNY-----------TNDDFIE------KQAVKDLNLVTANGTA-SLEFTKLILKL--------- +DILKKAVFVLRNE------------WADWEPAYLASQLNSNLWTTEFASDVA-EPV---SIG-GL------------------KVEASTNLYKL--EQSDLVVMIGGN--SWDTD-DERLTNVIGQRLGADKKTAAICGAVDFLARG-------GLLSQFKHTG--NAQYLWN---DF-SRY-----------VNDDFIE------QQAIRDRNLVTANGTA-PLEFANLTLKM--------- +--MKKAFFFLLDN------------YADWEGAFLASRLNSKEWTVETVSLEKGTCK---SIG-GF------------------TTMIDHSIETL--SYVDLFVLIGGN--SWKLEESSKLNKLISIYLNDGIVVAAICGAVDFLARN-------GILNDYKHTG--NSPCLWR---GY-NKY-----------KNKNFIL------KQVVVDRNLITANGTA-CIEFSECVLKN--------- +SLMKQAIFVMMDQ------------YADWEGAHLSSRLNMTDWTVKTASNQP-EVT---SIG-GW------------------TTRVDYQISEL--PEMTLLVLIGGN--AWQHD-DPRLTALIQQCLQRKVIVGAICGAVDYLARN-------GLLTGYRHTG--NAQFSWQ---SF-PKY-----------QNTDFEL------QQVVVDRQLVTANGTA-ALSFTSAVLKA--------- +CAMKNITIVIPDR------------FADWEYSLIAPVLHTTNYRVRYAAADLNHKT---SMG-AL------------------RVIPDLNFADIPA--NAALILIGGQ--DWRELNPATLAAHCERQKTDGNLLAAICDGAWFLAAN-------GLLNDRRHTG--NHLDAYR---AE-AAY-----------HNAQYQD------SEAVRDTNLITAGAMA-APAFSRAVLEA--------- +-MEKEIVFVLLDE------------FADWEAAFLAPALCPGSYAAKYMSPDGESVR---SIG-GL------------------RATPDYDASTL--ESCAGLILVGGM--QWESAAARRIAPLAGEALKRGILVGAICNAVSFMAAN-------GLLNSVRHTG--NTVEMLK---QWGANY-----------TGVLYEE------RQAVRDGNVVTANGTG-YLEFTRECLLA--------- +MIMKNIVFLILDE------------FADWETAFLASALNTQNYSVSYASTDKDIKI---SMG-NL------------------KMLPDMTLEEIE-DNTDGLILIGGK--TWRNQTNYTIIELVKKFNYPNKVVGAICDAAYFLATN-------GLLNDCKHTV--NNLAEIK---DN-ENY-----------TNENFVK------AESVIDGKMVTARGDS-PLHFAKDVMKA--------- +VPVKTLAVVILDK------------FADWEPALLAAGLQIGGYTVRWASVDREVKT---SMG-GL------------------RVEPDMIISEVPS--ADAVIVVGAG--SWRTLSAEQLASILGDFKDAGKPVGGICDGAYFLASA-------GLLDGRRHTA--NSFEDIK---DL-PAY-----------TNHQYVN------TEAVRDKNLVTASGVG-FVDFTFEMLHA--------- +--MKKIIFIILDK------------FANWELAYLSAALGTEQYSVLYASTDKEVKT---SIG-NL------------------KALPDLSIWEIE-DISALIFIGAEG--SWHNLQTSQLVTLAQKIV-NGKVLGAICDSARFCAVN-------GLLNDVKHTA--NTFDEIK---DA-TLY-----------TNENFVLT----ANEAVTDHKVVTAKGDS-ALHFAVSVLRA--------- +DSRKEVLFVLIPE------------YADWEFALLAPGLREPQYDVRTVAADEGPVM---SIG-GV------------------RCLPDYTFQTI--DDYAALVLVGGS--NWWGEEAQRVVPLVEHALARQVVVGAICDASAFLGAN-------RFLNDVDHTS--NGLAYLQ---SRAAAY-----------SGARYRD------VPSVRDGNLVTANGVG-FIDFTCNMLAA--------- +FMTQKVLFILLNE------------YADWEGAFLSTALHEAKYEVNIVAPTLDEVR---SIG-GF------------------RTLPDYSFENM--EEYAALVLIGGN--RWNSAEAELVVPLVQKALDNGKIIGAICNGASFMCSH-------GFLNNVKHTG--NGLDQLK---LWGDKY-----------TNSGYIE------AQAVSDGNIVTANGTG-HLEFTREMLLL--------- +--MKKVYVYVLND------------MAECEIGYILQAFSTKEFEVETVACNKKPIL---TLG-GL------------------TIIPDRAISEVDFSNIAALLLPGSS--AWGSED--EILKKAQECLRNDILVGAICGATLALADY-------GILDRFKHTS--NSLEYLN---FFSKNY-----------AGDLYVC------SNSVSDRNLVTANSAG-SLEWTKDILKN--------- +-MKKIIYLYILES------------MAEWEVGYILQAISNREFVIKTVSASKNPIQ---TIG-GL------------------IITPDCLLDEIDENNMVALLLPGAE--SWNSEE--QILEKALSYIDKGILVGAICGATLALADL-------KVLDKFKHTS--NSLDYLT---LFSKQY-----------SGELYVN------SPAVIDCNLITANSAG-GLLWAKHIIQY--------- +---MKVYIYILNT------------LADWEIGYLTAELNRLPVEIIKIGNTTEPIK---TMG-GI------------------TITPDENIDNIKFEEDDLLILPGAD--TWTEEEN-KIIDIVSSIIDEKVIIAAVCGATIALANK-------GILNNRKHTS--NDLEFLK---MFCPEY-----------TGNFYIN------QPAVTDDNLITASGIA-PLEFSYEVLKR--------- +---MKVYLAVLDT------------LADWEIAYLTAELYETDCEILKVGLTPSPIR---TMG-GM------------------EIKPDLVLPELSLDENDLLVLPGSE--LWEDPQ--PFLHFAGTALAEGRNVAAICGGADGLARI-------GALNHRPHTA--NNKDNLL---ASYPEY-----------AGAHYQE------APAWRDANLITASGLA-PLEFAREVIGL--------- +MSKNTIFMYVLNT------------MADWEWGYITAELKIPAFTIKTVSLNKEPIT---TMG-GL------------------RIIPDLSIDEINNQDCALLLLPGGE--TWMDSQH-LILKKAKDCLDSGIPVAAICGATMALASV-------GILDAYRHTS--NDFAYLK---KECPNY-----------HGENFQF------QSAVTDGDLITASGIA-PIELAYQVFKR--------- +--MKNVYFYIIDG------------LADWEISNILAELNAQTINIEMVSNSKSPIT---TMG-GI------------------NINPESLIEEISISKDTFLILPGSD--TWNDSK--PVIKIAKEILSNGGYVGAICGATIPLANI-------GILNEYYHTS--NDLLYLE---SFSSNY-----------HGKLYID------KPSVSHKNLITASSTG-TLMWTKDILQK--------- +-MNKIIYVYLLDT------------MADWELSYVLSAVNSHKYTIKTVGYTKDTIQ---TMG-GL------------------TVTPDCSIAEIDSNQMAALLLPGAN--TWDAPQ--ALLKEVPDYLEQGILVAAICGATLALANL-------AVLDTRKHTS--SALEFLT---GFSPTY-----------KGALYQQ------ALSMTDNNLITASPAG-ALLFAKQILTA--------- +--MKYAYVYVLDT------------MADWELGYVIAELNAGRIPVKTVGAAKSPIT---TKG-GM------------------TIMPDTTIEEITLESSAILLLPGAD--QWRNPE--LIVEKAKQLLDAGGNAAAICGATAALANA-------GILNHRQHTS--NSLEYLA---MCCPAY-----------EGACYRN------EKIVVDGNLITTSAAG-GLLLAREVIKL--------- +-MTKQMYLYVFDS------------VSDWEYGYVMAELKEKPLHVITVGVSRDTIT---TMG-GL------------------RVKPDITVEEMNVSEQDLIVLPGGE--SWGHPIH-LMLKQVDNAFNQRAFIAAICGAVHGLAKA-------GYLEHFHHTS--NDQSYLE---MIYPAY-----------RGTLHQN------GSVVRDGQLITASGVA-PLEFARETIGA--------- +SMMRSLYLYILDS------------LADWEPGYVLAELRSYQYDVILCGRSMDAVT---TMG-GL------------------YLSPDVLISDIHPSAGDVLLLPGAD--TWLDPS--QTLATVGRLLGEGMTVAAICGATLGLASA-------GLLDNRPHTS--NDLAVLT---MFCPAY-----------HGEYYVD------EPAVTDGNLITASGLA-PVEFAYHLFKK--------- +RIMYTIYVYVLDT------------LADWELGHVASELNAPRVTLKTVSCSREPVI---TMG-GM------------------KIVPDCITDDIEVSEASVLLLPGAD--TWNDPR--AVLEKADRLLSVGAAVCAICGATAALAGY-------GLLDNRLHTS--NGPGFLE---MFVPEY-----------KGGFYVD------MPSAADNNLITADSAG-ALLWTKQIIEY--------- +-MKKRILLVLKEE------------FADWEAAYLSSQILKGNYVVETVSLNKETVR---SIG-GF------------------RVVPDYGLDEV--ETYEALILIGGT--GWRKPDAGKIAPLVLQCVEKGRVLGGICDAASFLGTL-------GVLNTVKHTC--NDLKDME---AWADAY-----------TGALHQK------KQAVRDQNIVTANGTA-ALEFAREILFA--------- +MDKKEVIFVLLNE------------FADWEGAYIATCLNPVNYIVKTMSVTKDPVM---SIG-GF------------------KVLPDYDVNDM--KDHSGLILIGGM--RWFSPEAVQIVPLVEEAIRENKLVAGICNASVFLGAN-------GFLNNVKHTS--NGLDYLK---QYAEKY-----------TGAGYVN------KHAVRDGNIVTANGTA-PLDFCREILYA--------- +-MKKEILFVLLKD------------FADWEGAYIAPNLNESKYIVKTVSVRKEPVV---SIG-GF------------------KVLPDYGIHDI--ADYAGIVLIGGM--SWFTPEAEAIVPLVKEAIEKKRLVAGICNASVFLGIH-------GFLNHVNHTS--NGLDYLK---QFAVNY-----------TGNLYMD------EPAVRAGNIITANGFA-TLEFCREILYA--------- +--MKEILIFISNE------------YADWEIGYIGAEIRN-KYKISTVAINKEVII---SMG-GL------------------NVNPTYCIDEVLNENFQMLILCGGE--SWKKEKY-SVKKLVDMFKENNKPISTICDATTFLAFN-------GYLNQIEHTG--NSVEYMI---STCPNY-----------TGNNYIE------QQCVRTDYFITANGTA-TLEFSREIMKS--------- +-MEKEIVFVLLDD------------FADWEAAFLAPALRPASYGVKYMTPDGRPVR---SIG-GL------------------QAAADCDASAL--EACAGLILVGGM--QWQSEAAQRIVPLVGEALARGIVVGAICNAVSFMAAH-------GFLNGIRHTG--NTLGMLQ---KWGANY-----------TGALYEE------RQAVRDGNVVTANGTG-QLEFTCECLLA--------- +TEKKEILIVILNE------------FADWEISYVASFLN-DKYISKIVSVSDGVIT---SIG-GL------------------NVLPDYTLESA--EDFYGLILIGGN--SWRKPVSNKVIPIIEKALTMDIPVGAICDATVFMGVN-------GWLNEVKHTS--NELHDLK---TYADNY-----------TNKNYLL------EQAVTDRKIVTANGTA-SLEFAREILEL--------- +TEKKEILIVVLEE------------FADWEMSYVAAFLN-DKYITKIVSVSEGVIK---SIG-GL------------------NVLPDYTLKSI--EIFYGLILIGGN--SWRKPLNNNVIPIMEKALTMDIPLGAICDATVFMGAN-------GWLNEIKHTS--NDLNDLK---TYADHY-----------RNMNYVL------EQAVTDGKIVTANGTA-SLEFAKEILEL--------- +VSNKKVLFVLLDE------------YADWEAASLAAALNGQQFDVKTVSLTKDPIK---SIG-GF------------------TVLPDYEIADA--EDFVGLILIGGN--SWRKEESKQVMELVTKAIEKEVVLGAICDATVFLGKH-------GLFNTIPHTS--NYLDSLK---KVAESY-----------SNSGYLE------QQAVRSGKIITANGSA-FLEFGKELLEA--------- +--MRTVLLALLEQ------------YADWEAAYVSTGIHQGKFIVKTAALSEHPVT---SIG-GI------------------QAVADYTVDSA--EDYDALLLIGGM--RWREERAQQIIPLVRHCLKNDRLLGGICDAAAFLASI-------GVLNTVKHTG--NRLSALQ---EWPTEY-----------EGENFQA------RQSVRDQNIITANGSA-PLEFAREVLTA--------- +--MTEVFFVLLEG------------YADWESASIAAVLN-EGVTVKTVSNEKQAIH---SMG-GF------------------SILPDYTFAEA--KDFDALILIGGT--SWRTDKAEAVDALVEKAQEQGAVIAAICDATVYLGKL-------GLLNDHKHTS--NQLQDLQ---DYAEKY-----------KGNQFVE------VQAIKESNLITANGTG-HLEFAREILLT--------- +---MKALFFLYEG------------YVDWEISLLSYILNVTGVEINTTAL-NDEVI---HKG-MF------------------KVKLDMNIEACNPNDYDVLIIPGGP--DPF-VKD-RVLNLIREFDDQGKVISAICGGSAFLAAA-------GVLRKRKYST--SIDDDLA-----YKHY-----------FNAFKSE------TDVTVCENLITAEGNA-YVEFAVAVGKR--------- +---------MYEG------------ISDWEFGYVIAHINNHSYEVKTVGRGKNSVK---SKG-GI------------------TMLPDLTLEELNPLDSEMLILCGSD--NAAIGG-IDFIQKARLFIEQNKSIAAICGATAALAKE-------GLLDERSHTS--NSKEFME---MT--GY-----------SGKYYVN------APAVTCNRVITASGIE-PVAFAIEIFKT--------- +METREVILFVFDG------------LSDWEIGYVTPGIQPGAWRVRVVSAGGRPVT---TMG-GL------------------RVLPEGSLEETDPAEAGMLVLPGGM--AWERGG-NEALDLAARFLEAGVPVAGICGATYGLARA-------GLLDRRRHTS--NAREYLA---AT--GY-----------RGDLYEE------APAVTDGDVITAPGVS-PVDFALHIFRR--------- +MSQQTVYLFVFDT------------LADWEAGFAIAHINPGRYQIRTVGLTRDPVR---SLG-GV------------------TIVPDLGLADLRSEGTALLILPGGT--VWDAEG-IAATDKARELLAAGVPVAAICGATAGLARA-------GLLDDRAHTS--NARDYLE---AT--DY-----------KGAHYRD------TLAVTDRDVITASGLG-ALEFAREIFRL--------- +--MGQVVLYAFDT------------MADWEYAYITTVLQDDRYRLVVAGAGE-PVT---TLG-GL------------------RVLPETTLDDLDESDVDLLLLPGGN--TWLDGE-HAALALAGRLLDSDRQVAGICGATRALARA-------GLLEHRAHVV--DAD---A---DE-PDY-----------PGSARVH------ASIAHDGPLITAIGEA-PLEFSRAVFMA--------- +------MLYAFDT------------MADWEYGPLAGALGMA-VDLIVAGDSA-EVS---TFG-GL------------------RLHPEYTLGELDPAHIDMLVLPGGS--TWHRR--HAILGLGADRLAHGQPVAAICGATLGLARR-------GLLDARRHTS--NSADFLA----E-SGY-----------RGGLYEE------ARVVVDGPLITAPGTS-ALEFTREILVA--------- +--MTTVYLALVDG------------LSDWEYGHAAAQINPGRYEIKTVAVSLDPVR---TIG-GV------------------RMLPDVTIADVDVAGSAMLILIGSD--SWEAGA-NALGQLARRFREAGKPVAAICGATIGLARE-------GLLDDVKHTS--NFPGELG-------EY-----------GGELYQD------VRAMRDRGVITAGGAS-ALEWTREILLE--------- +MESGTVYLAVYDT------------MADWEYGYVMAHLNPGSITVKTVGRTLEPAT---TKG-GI------------------RILPDLCLDDLQIKQAKMLILPGGD--SAESDG-IDFADKAVQCVAEGVPVAAICGATVALAKK-------GLLDNVPHTS--NAAAYLE---MT--GY-----------QGAHYRQ------QPAVSSDLIITAGGVA-PIEFAVEIFRK--------- +TAPRPVLLAIYDT------------LADWEYGLASAHINPGRFTVVTVGLIDAPIR---TMG-GM------------------RVVPDITIDEVDESTTAALILPGAE--AFSAGY-GQWADLAERLLAVGIPVAAICGATSALARH-------GLLDHRPHTS--NAAEYLG---AQ-PGY-----------RGEFYVD------ELAVTDGDLITASGIA-PAHFARAVLAR--------- +MQTKHAFLYVFNT------------MSDWEYGYLIAELNLDPLNVLTVGATKEMIT---TMG-GL------------------KIKPDLSLDECSLNSKDLIILPGGT--TWNEDIH-PFLERIDQALKRGTIVAAICGAIEALANR-------GHLDKRKHTS--NNLDYTK---MVCPNY-----------KGMFYEN------RSAVSDANLITASGIA-PLEFAIEVLKK--------- +KPTKIIYLFLFDT------------LSDWEIGYVTAGINPEKYQLKTFSLDGKPIR---TIG-GL------------------LITPDLSLDEVTFSDAEMLILPGGA--SWDEGG-NKVTLLAKKFHENRIKVAAICGATLGLAKI-------GLLDSIQHTS--NSKDYLL---NS--HY-----------QGEYYVD------VLSVSDEGVITASGTA-SLEFAREIFKE--------- +GTRSDVVLYATDT------------MADWEYSYVTAGLAAESFRLRVLAD-QSEVT---TKG-RL------------------RLRADADLGEVDPEDVALLVLPGAD--TWSDG--HKVLDLARVLLERHTPVAGICGATYGLARA-------GLLDDRAHTS--NAPDFLV----P-SGY-----------AGARYRD------ERVVEDGDVITAPATA-PVDFGAAVFRR--------- +-MTTTIALYATDA------------MADWEYGYLIAGLAPDANRLIIASEAE-AVT---TMG-GV------------------RIVPDVSVADLPT--LDALILPGAD--TWNSG--HTVLTLAAELVAAGKPIAAICGATYGLART-------GLLDNRPHTS--NAAEFLT---QA-IEY-----------RGEHYRD------DRAVSDGTVITAGGVN-PLEFAKLVFER--------- +ITIKKIYLYVFDT------------MADWEPALLIAELRTLKYEVATVSLTLNPVT---TMG-GV------------------KILPDMTLAELSAEDVALLILPGGN--TWLEPFH-PVFPVVRELLERSIPVAAICGATIGLGAN-------GLLDRHKHTS--NDLGFLK---ACCPTY-----------AGAMYVN------KPAVCDGPLITASGVA-PLEFAYETLKK--------- +-MTRYVNIALLDT------------LADWEIGYLTSYVNPGSVRIRTVGTTAEPIR---TKG-GL------------------AVTPDVVLADLSLDDSAMLVLPGAD--TWAEPD-NVWLEQVRRFLDHGLPVAAICGATYALAAA-------GFLDDRPHTG--PAKEFLA---SS--GY-----------GGEHFVD------EPVVADGDLITANPVA-PVEFARAVFER--------- +-MTSDILIAVYDG------------LADWEIGYVTAGLNPGRFRVRTVGENLNPIT---TMG-GL------------------TVVPDVALADADIDGAALLVLPGAD--SWLEGA-NAFSAAAVSRLDNGKPVAAICGATVGLAAA-------GALDTRDHTG--NAPEQLA---IA-ASY-----------AGERFRT------ERAVSDQGLITAGAAS-PLEFAVEVFRT--------- +MQTKKAFLYVFNT------------MSDWEYGYLIAELNLAPLKVITVGANKEMIT---TMG-GL------------------RIKPDISLDECTLESKDLLILPGGT--TWSEEIH-PILERIGQALNIGTIVAAICGATDALANM-------GYLDTRKHTS--NNLEYTK---MVCPNY-----------KGKFYEL------GPAVSDANLVTASGIA-PLEFAMEVLKK--------- +DLRAPLHLAVHDQ------------MADWQFGHATAHVRFGHRDVVTVGLTGSAVT---TAG-GL------------------TVLPDISLPRLKPSQSAMLLLVGSP--QWEDSPDSPLASAAGIFLDAGVPVAAIGSATVGLARE-------GLLDYRDHTG--LDPAELL---A--TGY-----------AGHRYRA-------PVVSDGDLLTAGPSA-PLAFAREILLT--------- +PPARPVHLAVYDT------------YADWETGHTTAHLT-RGHRVRTVGFAGAPVT---TMG-GV------------------RVQPDLALADLSPEDSSLLILTGAS--LWDTGDDLPFAAKAREFLAAGVPVAAICGATAGLARE-------GLLDAYDHTS--AAAGYLA---EQ-PGY-----------AGGRYVE------ADAVTDGDLITAGPTE-PVAFAREVFAR--------- +-MPQTVHLYVFDG------------FADWEAAFAVAGIQPGQWQVRTVGPWHAPVR---SAG-GL------------------TVVPDLGLDQIRPADSAMLILPGGD--GWEDND-SWAINKAGDFLDQGVPVAAICGATAGLAKA-------GLLDDRNHTS--NAQAYLN---GT--GY-----------DGAFYRN------EPVVVGSGLITAGGMA-PLEFARAIFSE--------- +TTSKSVFLFLCPG------------MADWEPAYTISLLSNNSYPVRTFGVTQEPVR---SVG-GL------------------TLVPDFSVDNVNIDDVAMVILPGSI--YYEKEDPDQLASLISRCTQAQIPVAAICGGTLFLARH-------GFLDDVRHTS--AGNEWLK---AHAPQY-----------QGQYYTP------SPSISDKGIITANPLG-FLEFAAHIFLE--------- +NNKNEVLLLLTDR------------WCDWEAGYAIAVINFSDYVVKTISTDTIAKV---SMG-NI------------------KAEVDYCISNYNINNLAMIILPGGL--SWEENEHDEIAGFIQSAVKSDVPIAAICGATLFLCKN-------GFLNHVKHTG--DSLELFQ---SQ-KNY-----------NGSLYLP------AQVVVDGGFITANETA-AVEFAYYIFKA--------- +-MTKLLACYATDT------------MADWEFAYLTTLVAPGTCEIQFVGDRE-DVH---TLG-GL------------------NLKPDVDLDELDLDQLSVLVIPGGD--TYGSG--HPLLEIVRECERQGVPVAAICGGTIALARA-------GVLDHRKHTS--NAMEFLV----G-TGY-----------LGDNYSD------APTESDRGVITASGIY-PVQFTAAVLRE--------- +EPKGTVVAYLPER------------FADWEAGLACAELNHTGYQVRTMSADGAPRH---SIG-GL------------------TVTPDLAAGALPD--TRLLILVGGE--SWPGTSND---PLIDECVARGVPVAALCGACTFLANH-------GYLDECDHTA--NARYELD---QLAPAY-----------RGEHFHC-------PAIDGGAFITATGAA-SVEFALLVMAR--------- +SSMKIIAIYATET------------MSDWEYAYLTTEAQPDRFKVLFVGESLEAVR---SKG-GI------------------EVVPALTLQDV---QIAAFVVPGAD--TYF-DGHE-LLETVNVLKENEVLLAAICGGTLALARA-------GVLDHCQHTS--NARGFLA-----SMKY-----------ANDGYKE------E-AVFDRGVITASGLA-PVPFTAAVLRA--------- +MHPAKIALYATDT------------MADWEYAYLTTQLSPGRFSLVIVGDGT-PVT---SMG-GL------------------PISPSVDLADIDDDSLAALVIPGSD--RYESG--HRLAETTRALLDRDVPVAAICGATFLLARN-------GLLDARDHTS--NAAEYLQ----M-TGY-----------AGERYRD------APVVTDGGITTASGIR-PVPFTAEVMRR--------- +--MRTIALYTTET------------MADWEYAYLTTEQLPGRFRLLLVGDGLNPVR---TLG-NL------------------PLTPEADLDTLQALALAALVIPGGD--HYE-AGHD-LIEAVGRLVDEEIPVAAICGATLLLARG-------GFLDERRHTS--NAAQYLE-----ASGY-----------RGAHYVE------A-VVTNRGVTTASGIH-AVPFTAEIMRI--------- +TMKKEILVFIFDG------------YADWESAYICSELN-TDYIVKTLSLDKEPKI---SMG-GF------------------RIMPDYSVSDY--NDFAMLLLIGGY--AWMEQKNNDIQPVVEYAVKHHIPVAAICNASNFMAEN-------GYLDNIEHSG--NTLDYME---SQAPHY-----------KGSNFIE------KQAVECSGIITANGTA-SLEFAKEIMLY--------- +MTKRKCAIFLFDG------------YADWEPALAIAGL-YGGFEVNSFGINREPII---SNG-GL------------------KILPDLNADEVNVDDYELLIIPGGA--AWEEGKNREIIPLVTEFQQKKRKVAAICGATILLAEM-------GLLNASKHTS--NDSEYIR---QFCPSY-----------QGSLYQK------EPATTDNGIITANGAA-MVEFAHEIFKS--------- +--MNTVLILLSEP------------FADWEAAYICPELNE-DYEIKTVSLSKAPVT---TMG-GL------------------KVLPDYDIDNIPEINIKLLLIPGGL--SWDNTE--KYCKIIRYCLENNILTAAICNGVTFLADN-------GFLDNRRHTG--NTLEYLK---QYAPAY-----------KGKEYVE------SQSFIYENLITANGSA-AVEFSRDILKK--------- +--MKEVLIFITDG------------FADWEASYVSSELNGTGYRVKTIAIDQEPKV---SMG-GL------------------TVLPDYSVNEFNPVDIAMLIIPGGT--GWREEK--QAKVMVEYCVSRDIPVAAICDATTFLGNH-------GFLDNHRHTG--NTLAYLK---EGAPNY-----------RGQHYVE------GQSIWDENLITANGSG-ALEFSRHILER--------- +PVKKRAYVFLFDG------------FSDWEIAYLTPEI-SKACELLYFSAQGQTVH---SMG-GM------------------KVVPDIALEQMNTNEVDLLILPGGT--AWEKGENNVLDQLVRLLFEQGKTIAAICAASAYLGQK-------GFLDRLQHTS--NDLQYLK---GVAPQY-----------LGKNYLN------TLAVADQNIVTANGIA-PIEFAREVFKK--------- +--MKNVYIFLFDG------------YSDWELGYLTPEI-NEELKIKTFSADGNSVR---SAS-YL------------------QVTPEYSLKDIKIEDIDILILPGGF--TWDGGLDYMLP-FIKQVHDKKITIAAICGATIFLARN-------GFLDNVKHTS--NDLQYLK---MVAPNY-----------TGHLYQH------EKAYSDQHIITANGTA-PIEFAKEIFKA--------- +MEANHIYIYLFDG------------YSDWEIGYLMPEL-DSRYQVLTVSNTGADVT---SVG-GL------------------KVKVDCSLEDIDISTLKLLILPGGE--MWEKSTNNAIDRVVYGIYKYQLPIAAICGATLYLAQK-------GMLDYVKHTS--NALFYMK---GFVPTY-----------HGKNYVD------QLVVRDQNVVTASGIG-ATEFSREVMKV--------- +--MKNVLVFIIDG------------FADWEASYVTAELNGTGFQVQTIAIDKNPKK---SMG-GL------------------TVLPDYSLLDFPFLEITMLIIPGGT--GWKEEK--QAKKLVEFCFTEDIPVAAICDATTFLGNH-------GFLEQYKHTG--NSLAYLK---EAAPNY-----------KGEKYID------QQSVSDGSLITANGTG-ALEFSRDILCK--------- +HIGKYVYILVFDG------------MADWEPAIALCEL-RGQLSVVSVGFSKESIT---TMG-GL------------------KVTPDITLSEISYDKTLLLLLPGGE--MWQKKKPETLESMLIDFHKQGVPIAAICGATITLARA-------GLLRGIRHTS--NAPGFLD---QFAPDY-----------CNSDYVV------DFAVRDGNIITANGGG-SVEFARLIIEL--------- +--MKTAYLLVFDG------------LSDWEPGLAIAEI-SKKYQVKTIGLNQNTVT---TVG-GV------------------SIVPDYTLDEINYGDAALFLLPGGE--LLEKSPLPPLVPVVRRFRKLEIPVAAICGPTVFLARH-------GFLETAQHTS--NGKKYLQ---DLIGDY-----------PGDLYLN------QPSVSDKGVITANGIA-SVEFARDILSE--------- +--MKKTYVLLFDG------------YADWEIGFALAEL-MGNVPVVGVGLSDAPVL---SMG-GL------------------KVQPGRRLSDIAIDDILLFILPGGM--LWEQSYPKEIHSFLQNLDERKIPTAAICAATTVLAKA-------GLLQNRKHTS--NSLKYLR---DHVPGY-----------TSDHYIE------ALAVTDGHITTASGLG-SIDFTMKIMEA--------- +-MRDTVYFLAFDG------------FADWHAAHALCEIRPGDWQLKTVGFSMQPVL---SMA-GL------------------RVVPELTLDELDLRRAALLIVPGGY--LWEHGYGD-VVQAVGRLHAAGVPVAAVDSGVLVLARA-------GLLDACRHTG--SWPGHIG---THVPAY-----------AGEQYDA------NLAVSDQGVITASQLG-SVEFAREVIRT--------- +-MRDAIYFLVFEG------------FADWQAALALCEIRPGDWRVQAVGFSRAPVT---SMG-GL------------------CVQPQLTLDQLDDASAAMLIVPGGH--LWQRGEGA-AVVAMRRLHAAGAVVAGIDSGVLALARA-------GLLDDCRHTG--NWSGQLA---AQVPTY-----------AGEQYDS------ELAVSDGGVISASHLG-SVEFAREVIRT--------- +CSMKHICMYVQDT------------MADWEHGYLLHGVSTPVCTMSFAADARDAVT---TAG-GM------------------RIIPDETLAETDAEGIDAFVLIGGD--TWLSED-RAALDLAEAVLAGGGIVAAICGATLGLASR-------GLLNNRRHTS--NAPELLA---AI-TAY-----------RGDLYEG------TPATADRNVITAGSAG-SLLWAKLILEE--------- +--MKKICMYLMNG------------MADHEHGYLLTALSEPKYEFCTVALSKEPII---TMG-GL------------------KIIPDYILNEVNKDDIIALILIGADIQLWLNRE-QTILNLAIELLKRNILVAGICGATLGLASK-------GLLDERIHTS--NVEFLLT---NFVKNY-----------KGKNYRN------DVAVYDKKLITASSAG-SLLWSKYILEN--------- +--MKKICMYLCEA------------MADWEHGYALQGLSEKKYELLTVSNSKNPVH---TAG-GL------------------TIVPDAALKEIDGNSVSALLLIGGD--AWLKEE-QEALDLAAALVEKNAVVAAICGATLGLAER-------GILNDREHTS--NSPSFLS---GLAKNY-----------GGAHYRH------VPAVCDGNLITASAAG-SLLWARYIIER--------- +GMMKTVYMYVQDT------------MADWEHGYLMQALS-PKVSFKTVGRTKAPIR---TAS-GI------------------TLVPDLSLDDIDVASTAALVLIGGE--TWLDKE--AILNLAAELLQEGFLVAAICGATLGLADR-------GALNTRFHTS--NASFY-P---EMSPHY-----------TGIYYKD------DVAVCDGNLIIASSAG-SLLWAKLIVEK--------- +----------------------ATGCEEMEAVIIIDVLRRAGADVTVASVEDS-------LQVEMSRK--------------VKLVADKLIGDVSQESFDAIALPGGMPGAERLSKSAALLQILNEQIKSGKIWSAICASPAVVFE------SQGWLKGKKATSHPAFSDKL-------------------AD---QSEV-----PSRVVVDGNLITSRGPGTAFEFALTLVE---------- +----------------------GNGSEEIETACVVDTLRRAGADVTLASVEPS-------VSVTMSRG--------------MVFQADHTVSSL-SPPFDAVALPGGMPGAQRLADSAHLAKLVTHTRDNGKVVGAICAAPAVVLA------GQGVLDGKNATCYPAFRDKI-------------------PN-----VA-----EGDVVRDGQLITATGPGTALKWSLEIVE---------- +---------------------KNTGWYLPGAAYPYYVLSP-YFDIDFAVPKGPNPVDPSS----------------------------TELSGVKADDYDAIFHVGGYGPIIDLPEDPA--------------------------NIKLGS-----------------------------DDVPFLVEDKIKSLGAAR----------GLVFGNVIAGQNPASARGVAEAILKES-------- +---------------------------------------------------------------------------------------TKTLAEVKPEEYDGLVIPGRRVPYVRVVASGDVKRVVRHIFERNTPVAAICYAPAT---A-------RVVKGREVTSHIAVGP-------------------EAENNGGIWVD------QEVVVDGNLVTARAWLDNPAWMREF------------ +----------------------------------------------------------------------------------------------------------------------------AGFLEAGKVVSAVCHGPAALANVKL-SNGTYLIAEQNFIGISDVEEDIIQFSR----DMSFLLETELRKYGGIYEKAVGRFGVKVLTNGKLYTGQNTSSSALVGDNIIR---------- +-----------------------NGSEEIEAVNLIDVLRRAGANVIVASVEEKLQI----VTR---------RH-------KFNLIADMMLDEAIKMQFDLIVMPGGLQGAQKFASTKQLVDLLKKQAESNKPYGAICASPAHVLEP------HGLLKGKKATAFPPMSHL-------------------LTDQSA---C-----EHRVVVDGNLITSRAPGTATEFGLAIVEKL-------- +-----------------------NGIEEMEAIILVDALRRANADVVVASAEDGVV-----VTA---------RY-------GTRIVADVMADCVAG------PPPGGMPGAKTLGGCEQLVALLKKQAEANTARSPTCSSPMAC-------------PGKKATTCASMAGL-------------------LADGGE---C-----ENRVVVDGNVITSRSPGTAMEYAAAVVEKM-------- +-----------------------HGSEEIEVVTVVDILRRAKAKVIVASVEKSLEV----LAS---------Q--------GTKIVADILIGDAQESPYDLIILPGGTAGAQRLSKSRILKKLLKEQNSAKRIYGAVYSSLAI-LQK------QGLLKDKRTTAHPSVLVK-------------------LKDEEI---N-----GAKVDIDGKLITSEVLATVTDFALAIVSKL-------- +-----------------------NGSEEMEIIMLVDILRRANLNVVLASVDESTNI----VGS---------Q--------RLNIVADKCILGASDSKYDIIIIPGGPAGAERLHRSTTLQRLLKEQKQESRMYGGIGYSPLI-LQK------QGLLQDKTATAHPSIVNQ-------------------LTCQVI---D-----RSKVVIDGNLITGKGLGTTMDFSLAIVRKF-------- +-----------------------NGCEELEIIILVDILRRAKINVVLASVEKYPAV----LGS---------Q--------RMKIVADKSIMSASDSIYDLIILPGGPAGAEQLHRSRILKKLLKQQMQAGRMYGGVCSALKV-LQQ------EGLLEDKTVTAHHAVASE-------------------LTCQVI---D-----QPNVVIDGNLITGKGLGTVVDFALAIIRKF-------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASVNESTNI----VGS---------Q--------RIKIVADKCILDASDSKYDLIIIPGGPAGAERLHRCTTLKKLLKEQRQASRMYGGICYSPLI-LQK------QGLLQDKTVTAHPSIVNQ-------------------LTCQVI---D-----RSKVVIDGNLITGKGLGTVIFPGHCKKILW-------- +-----------------------NGSEEMEALNLIDVLRRAGARVTVASVEDTPRI----VTR---------HY-------KLNLITDVMLEQAAEMEFDLIVMPGGLPGALKFTSSEKLVGMLKKQAESGRPYGAICASPAYVLEP------HGLLKGKKATSFPPMAHL-------------------LTDQSA---C-----EYRVVVDGNLITSRAPGTATEFALAIVEKL-------- +-----------------------NGSEEMEALNLVDILRRAGANVTVASVEDTPRI----VTR---------HQ-------KLGLVADVLIEEAAEMQFDLIVMPGGLPGARKFAGTDK--------------------------------------LGKKATPFPPMAHL-------------------LKDRSA---C-----EYRVVVDGNVITSKAPGSATEFALAIVHKL-------- +-----------------------NGSEEMEAVMIIDILRRAKANVVVASVEDKLEI----LAS---------R--------QIKLVADVLIDETAKLSYDLIVLPGGLGGAQAFANSEKLVNMLKKQKESNRPYGAICASPALVLEP------HGLLKGKKATAFPAMCNK-------------------LSDQSE---I-----ENRVVVDGNLITSRGPGTSMEFALAIVEKF-------- +-----------------------DGSEEMEAVMIIDILRRAKANVVVASVGDNLEI----LAS---------R--------KVKLVADMLLDEAAKLTYDLVVLPGGLGGAQAFAKSDKLVNLLKKQAESNKPYGAICASPALVLEP------HGLLKGKKATAYPAMCDK-------------------LSDQSH---I-----DNRVVVDGNLITSRGPGTSMEFALGIVEKF-------- +-----------------------NGTEEMEAVMIIDILRRAKANVVVASLEGTLEI----VAS---------R--------NVKMVANVLLDDALKQQYDLILLPGGLGGAQAYAKSDKLIGFIKKQAEANKLYGAICASPAIALEP------HGLLKGKKATSYPAMWSK-------------------LTDQSE---C-----KNRVVVDGNLITSQGPGTSMEFSLAIVEKL-------- +--------------------------EDYEAMVPFQALQAFGLAI---YPRKKSDDVCCTAIHVLA--DTQTYSETVGHNF--ALN--ATFDEVDASSYDGLWVPGGRA-PEYLAHIPGVVELVTKFVSLGKQIASICHGQLILAAA-------GVVEGRKCTLFLLLNQ------------------------------------------------------------------------- +--------------------------------------------------------------------MAFTYSESRGHNF--TLN--ATFAEIEFNAYDGLVIPGGRA-PEYLAMDQSVVDLVSKFSHAGKPIASICHGQLILAAA-------NVVKGRKCTAFAPVGP------------------------------------------------------------------------- +--------------------------EDYEAMVPFQALQAYGVSVDAACPGKKAGDSCRTAVHQGI--GHQTYAESRGHNF--ALN--ASFDEAV-------------H-REYLAMDEKVLDLVRKFSDAKKPIASVCHGQLILAAA-------GVVQNRKCTAYPAVKP------------------------------------------------------------------------- +-----------------------NGTEEMEAVIIVDILRRAKANVVVASVEDKLEI-----EAS-----R-----------KVKLQADVLLDEAAKTSYDLIVLPGGIGGAQAFANSETLVNLLKKQRESNKYYGAICASPALALEP------HGLLKGKKATGFPAMCSKL-------------------SD---QSEV-----ENRVVIDGNLITSRGPGTSIEFALVIVEKL-------- +-----------------------YGFEEMEAVIIIDILRRAKANVVVASVEDYLEI-----VAS-----R-----------NVKLVADMLLDEAAKLSYELIVLPGGLGGAQAFGNSETLVKLLEKQRESNKYYGAICASPALVLER------HGLLKGKKATAYPAMCDRL-------------------SD---QSEV-----ENRVVVDGNLITSRGPGTSIEFALAIVEKL-------- +-----------------------NGSEEMEAVIIIDILRRAKAKVVVASVEDKLEI-----VAS-----R-----------KVKLEADMLLDEATKLSYDLIVLPGGLGGAQTFANSETLVSLLKKQRESNKYYGAICASPALVLEP------HGLLKGKKATAFPVMCDKL-------------------SD---QSEV-----ENRVVVDGNLITSRGPGTSIEFALAIVEKL-------- +---------------------------------------------------------------------------------------------------------GGLGGAQAFAKSEKLVNMLRKQKDTNKPYGAICASPALVLEP------HGLLKGKKATAFPAMCDKL-------------------SD---RSEA-----ENRVIVDGNLITSRGPGTSMEFALGIVEKF-------- +-----------------------DGSEEMEAVMIIDILRRAKANVVVASVGDNLEI-----LAS-----R-----------KVKLVADMLLDEAAKLTYDLVVLPGGLGGAQAFAKSDKLVNLLKKQAESNKPYGAICASPALVLEP------HGLLKV------------------------------------------------------------------------------------ +-----------------------DGSEEMEAVMIIDILRRAKANVVVASVGDNLEI-----LAS-----R-----------KVKLVADMLLDEAAKLSYDLIVLPVRRTWWCP----------------------SICQL------------------------------------------------------------------------------------------------------- +-----------------------DGSEEMEAVMIIDILRRAKANVVVASVGDNLEI-----LAS-----R-----------KVKLVADMLLDEAAKLTYDLVVLPVCWNSVIFPSPNSSQFSFF-----------VIYFN----------------------LVFPIYREDL-------------------VV---PKHL-----LNLISW-------------------------------- +-----------------------NGTEEMEATMIIDILRRAKANVVVASLEETLEI-----VAS-----R-----------KVKMVADVLLDDALKQQYDLILLPGGLGGAQAYAKSDKLIGLIKKQAEANKLYGAICASPAIALEP------HGLLKGKKATSFPGMWNKL-------------------SD---QSEC-----KNRVVVDGNLITSQGPGTSMEFSLAIVEKL-------- +-----------------------NGSEEIEAVNLIDVLRRAGANVIVASVEEKLQT-----VTR-----H-----------KFNLIADMMLDEATEMQFDLIVMPGGLQGAQKFASTKKLVDLLKKQAESNKPYGAICASPAHVLQP------HGLLKGKKATAFPPMSHLL-------------------TD---QSAC-----EHRVVVDGNLITSRAPGTATEFALAIVEKL-------- +-----------------------NGSEEIEALNLIDVLRRAGANVTVASVEDTLQI-----VTR-----H-----------KFNLIADMMLDEAAKMEFDLIVMPGGLSGAQKFACTDKLVDLLKKQAGSGKPYGAICASPAHVLEP------HGLLKGKKATAFPPMAHLL-------------------TD---QSLC-----ENRVVIDGNLITSRAPGTATEFALAIVEKL-------- +-----------------------NGSEEIEAVNLIDVLRRAGANVIVASVEEKLQI-----VTR-----H-----------KFNLIADMMLDEAIKMQFDLIVMPGGLQGAQKFASTKQLVDLLKKQAESNKPYGAICASPAHVLEP------HGLLKGKKATAFPPMSHLL-------------------TD---QSAC-----EHRVVVDGNLITSRAPGTATEFGLAIVEKL-------- +-----------------------EDSEEIEAIALVDILRRAKANVVIAAVGNSLEV-----VGS-----R-----------KAKLVADVLLDEVAEKSFDLIVLPGGLNGAPRLASCEKLVNMLKKQAEANKPYGGICASPVYVFEP------NGLLKGKKATTHPVVSDKL-------------------SD---QSHI-----EHRVVVDGNVITSRAPGTAMEFSLAIVEKF-------- +-----------------------NGSEEMEAVIIIDVLRRAGMGVVVASVEETLQI-----VAS-----R-----------KVKIEADNLIGEVSSAHFDAIFLPGGMPGAEHLRDSKELQSILARQAKDSRVYGAICASPAVVLEA------NKILAGKKATAFPAFQSKL-------------------SD---QSAV-----EARVVIDGLVATSQGPGTAMEFALAIVDKF-------- +-----------------------NGTEEMEAIIIIDILRRAKVNVVVASVEDSLEI-----LAS-----R-----------KVKLEADMLLDEAAKLSYDLIVLPGGLGGAQAFAKSEKLVNMLKKQRESNRPYGAMCASPALVLEP------HGLLKGKKATAFPAMCNKL-------------------SD---PSEI-----ENRVVVDGNLITSRGPGTTMEFALGIVEKL-------- +-----------------------NGTEEMEALIIIDILRRANANVVVASVEDKLEI-----VAS-----R-----------KVKLEADVILDEAAKLSFDLIVLPGGLGGAQAFANSEKLVNLLKKQSESNRPYGAICASPALVLEP------HGLLKGKKATSFPALCEKL-------------------SD---RSEA-----ENRVVVDGNLITSRGPGTSIEFSLAIVEKL-------- +-----------------------NGTEEMEAVMIIDILRRAKANVVVASVEDQLEI-----LAS-----C-----------KVKLEADVLLDEAAKLSYDLIVLPGGLSSAPTFAKSEKLVNMLKKQRDSQRPYGAICASPALVLEP------HGLLKGKKATAFPPVSDKL-------------------SD---TSEI-----EKRVVIDGNLITSKGAGTSMEFALGIVEKF-------- +-----------------------DGTEEMEAIMIIDILRRAKANVIVASVKDKLEV-----LAS-----R-----------KVKLEADMLLDEAAKLSYDLIVLPGGLGGAQAFAKSEKLVNMLKKQRESNRPYGAICASPALVLEP------HGLLKGKKATAFPPLCEKL-------------------SD---RSET-----ENRVVVDGNLITSRGPGTSMEFALAIVEKL-------- +-----------------------NGTEEMEATMIIDVLRRAKANVVVASVEDQLEI-----VAS-----R-----------KVKLEADVLLDEAAKLSYDLIVLPGGLGGAQAFAKSEKLVNLLKKQRESQRPYGAICASPALVLEP------HGLLKGKKATAFPAMCDKL-------------------SD---KSEI-----ENRVVVDGNLITSRGPGTSMEFALGIVEKF-------- +-----------------------NGSEEMEALNLIDVLRRAGARVTVASVEDAPRI-----VTH-----Y-----------KLNLIADVVLEEAAEMDFDLIVMPGGLPGALKFTSTEKLVGMLKKQAESGKPYGAICASPAYVLEP------HGLLKGKKATSFPPMAHLL-------------------AD---QSAC-----EYRVVVDGNLITSRAPGSATEFALAIAEKL-------- +-----------------------NGTEEMEATMIIDILRRAKANVVVASLEDKLEV-----AAS-----R-----------KVKMIADVLLDDALKQQYYLILLPGGLGGAEAYAKSDKLMGLIKKQAEANKLYGAICASPAVALEP------HGLLKGKKATSYPAMWNKL-------------------AD---QSEC-----KNRVVVDGNLITSQGPGTSMEFSLAIVEKL-------- +-----------------------NGSEEMEAVMIIDTLRRAKANVVVASVEDKLEI-----VAS-----R-----------KVKLIADMLLDEAIKLQYDLIVLPGGLPGAQAFSNSEKLVNLLRKQAESSKLYGAICASPAIVLET------HGLLKGKKATAYPAMCDKL-------------------SD---QSYC-----ENRVVVDGNLITSRGPGTSLEFALAIVEKL-------- +-----------------------NGTEEMEAIMIIDILRRAKANVVVASLEGTLEI-----VAS-----R-----------NVKMVADVLLDDVLKQQYDLILLPGGLGGAQAYTKSDKLVGLIKKQAEANKLYGAICASPAIALEP------HGLLKGKKATSYPAMWSKL-------------------AE---KRMR-----EQSRRRW-------QPDH-------------------- +-----------------------NGTEEMEAIMIIDILRRAKANVVVASLEGTLEI-----VAS-----R-----------NVKMVADVLLDDVLKQQYDLILLPGGLGGAQAYTKSDKLVGLIKKQAEANKLYGAICASPAIALEP------HGLLKGKKATSYPAMWSKL-------------------AD---QSEC-----ENRVVVDGNLITSQGPGTSMEFSLAIVEKL-------- +-----------------------NGSEEMEAVIIIDVLRRSKANVVIASVEDKVEI-----EAS-----R-----------KVKLVADMLLDEASKLSYDLIVLPGGLGGAQAFAKCDKLVNLLKKQKESNRPYGAICASPALVLEP------HGLLKGKKATAFPALCNKL-------------------SD---ASEA-----ENRVVVDGNLITSRGPGTTMEFALAIVEKF-------- +-----------------------NGTEEMEALIIIDVLRWVNAEVLVASVEDKLEV-----VAS-----R-----------KVKLVADVLLDDVVNGSYDVIVLPGGLGGAQAFAKSGNLVNLLKKQRESNRPYGAFCASPALVLEP------HGLLKGKKATAFPALCDKL-------------------TD---PSEA-----ENRVVVDGHLITSRAPGTSLEFAFAITEKL-------- +-----------------------NGSEEMEATIIIDVLRRANAQVVVASLEDTLEI-----VAS-----R-----------KVKLVADVLLDEAAKQSYDLIVLPGGLGGAEAFAKSAKLIDMLKKQRESSKPYGAMCASPALVLEH------HGLLKDKKATAFPALCNKL-------------------SD---PSEA-----ENRVVVDGNLVTSRGPGTTMEFALAIADKF-------- +-----------------------DGSEEMEAVIIIDVLRRAKIKVVVASVGEKLEI-----LAS-----R-----------RVKLVADMHLDEAANSSYDLIVLPGGLGGAEAFSASEKLVEMLKKHRESNKPYGAICASPALVLEA------HGLLKGKKATAFPAMCNKL-------------------SD---PSEI-----ENRVVVDGNLITSRGPGTSMEFALAIVEKF-------- +-----------------------NGSEEMEAVMIIDILRRAGASVVVASVEDKLEI-----VAS-----R-----------KVKLVADMLLEEAAKLPFDLIVLPGGLVGAQAFANSDMLINLLKKQVESNKPYGAICASPALVLEA------HGLLKGKKATAYPALCDKL-------------------TD---QSAV-----VNRVVVDGNLITSRGPGTSMEFALAIVKKL-------- +-----------------------NGTEEMEAVIIIDFLRRAKANVVVASVEDKLEI-----VAS-----R-----------KVKLVADVLLDEAVKLSYDLIVLPGGLGGAQAFASSEKLVNLLKNQRESNKPYGAICASPALVLEP------HGLLKGKKATAFPALCSKL-------------------SD---QSEI-----ENRVLVDGNLITSRGPGTSMEFALAIIEKF-------- +-----------------------SGTEEMEAVMIIDILRRAKGKVVVASVEDTLEI-----LAS-----R-----------KVKLEADLLLDEAAEQSYDLIVLPGGLGGAEAFAKSEKLVNLLKKQRESNKPYGAICASPALVLEP------HGLLKDKKATAFPALCDKL-------------------SD---KSEI-----DNRVMVDGNLITSRGPGTTMEFSLAIVEKL-------- +-----------------------DGSEEMEAVMIIDILRRAKANVVVASVGDNLEI-----LAS-----R-----------KVKLVADMLLDEAAKLTYDLIVLPGGLGGAQAFANSDKLVNLLKKQAESNKPYGAICASPALVLEP------HGLLKGKKATAYPAMCDKL-------------------SD---QSHI-----DNRVVVDGNLITSRGPGTAMEFALGIVEKF-------- +-----------------------NGTEEMEAVIIIDVLRRAKAQVVVASVEDKLEI-----LAS-----R-----------QAKLVADVLLDEAITSPYDLIVLPGGLGGAQAFANSEKLVNLLKQQRESNKLYGAICASPALVLEP------NGLLKGKKATAFPAMCSKL-------------------SD---QSEA-----ENRVVVDGNLITSRGPGTTMEFSLVIIEKF-------- +-----------------------NGSEEMESLMIIDILRRAGANVTIASVEDKLEI-----VAS-----R-----------KVTLLADMQIDEAAEKQYDLIILPGGLPGAQTFSTSEVLVNMLKKHADSQKLYGAICASPALVLEP------HGLLKGKKATAYPALCNKL-------------------TD---QSEC-----ENRVVVDGNLITSRGPGTSMEFALAIVEKL-------- +-----------------------NGSEEMEAVMIIDILRRAKANVVVASVEDKLEI-----LAS-----R-----------QVKLVADVLIDEAAKLSYDLIVLPGGLGGAQAFAKSEKLVNMLEKQKESNRPYGAICASPALVLEP------HGLLKGKKATAFPAMCNKL-------------------SD---QSEI-----ENRVVVDGNLITSRGPGTSMEFALAIVEKF-------- +-----------------------DGSEEMEAVAIIDVLRRAKANVVVAALGNSLEV-----VAS-----R-----------KVKLVADVLLNEAEKNSYDLIVLPGGLGGAEAFASSEKLVNMLKKQAESNKPYGAVCASPALVFEP------HGLLKGKKATAYPPMCNKL-------------------SD---QSHI-----EHRVLVDGNLITSRGPGTSLECALAIVEKF-------- +-----------------------NGNEDMEVITIIDALRRANADVVVASAEDGVEV-----VGR-----Y-----------GMRIVADVLLGAAADQQFDLIVVPGGMPGAKTLAGKEKLVALLKKQAAANMPYGSICDATAQVLEP------HGLLKGKKATA---------------------------AD---GSEC-----EDRVVVDGNVITSRSPGTAMEFAVAIVEKL-------- +-----------------------NATEGMEAIMIIDALRRAKADVVVASAEDTVEI-----VAR-----Y-----------DMRIVTDVLLDDTADQQFDLIIVPGGMPGAKTLSGKEKLVALLKKQAAANKPYGAIGAATAQVLEP------HGLLKGKKATTYTSMVCLL-------------------AE---PSEC-----ENRVLVDGNLITSRSLGTAMEYAVAIVEKL-------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASVDESTNI-----VGS-----Q-----------RMKIVADKCILDASDSKYDLIIIPGGPAGAERLHRSTTLKKLLKEQKQASRMYGGISYS-PLILQK------QGLLEDKTVTAHPSIVNQL-------------------TC---QVID-----GSKVVIDGNLITGKGLGTVMDFSLAIWIAA-------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASV------------GS-----Q-----------RMKIVADKCILGASDSKYDLIIIPGGPGGAERLHRSTTLKKLLKEQKQASRMYGGICYS-PLILQK------QGLLQDKTVTAHPSIVNQL-------------------TC---QVID-----RSKVVIDGNLITGKGLGTVMDFSLAIVRKF-------- +-----------------------NGSEEIEVVSIIDILRRAKVDVVVASVEKSVKV-----LAS-----Q-----------GVKIVADKLIGDAAGSIYDLIILPGGVAGAEQLQKSRILKKLLKEQEVDGRLCGAVCSS-ATVLHK------HGLLKEKRATAHPSTTREL-------------------TN----VVD-----GPKVVIDGKLITSRGLATVSDFALAIVSKF-------- +-----------------------NGSEEIEIVTIVDILRRAKVDVVVASVEKSVKI-----LAS-----Q-----------GVKIIADKLIGDAAGSIYDLIILPGGVAGTGQLQKSRILKKLLKEQDAARRMLGAVCSS-PTVLHK------HGLLKEKKATAHPSAITEL-------------------SN----PVD-----GPKVVIDGKLITSMGLATVSDFALAIVIKF-------- +-----------------------NGSEEVEVVTITDVLRRAKVDVTVASVERSLRI-----TAS-----Q-----------GTKIITDKLIGEAAESSYDLIVLPGGHTGTERLQKSKILKKLLREQHESGQIVGATNTS-TIILHK------HGLLEEKRTTVYPLDTDGP-------------------SN---HMIE-----GAEVVIDGNVITSLGLATVTKFSLAIVSKL-------- +-----------------------HGSEEIEVVTLIDILRRAKANVVVASVEKTLGV-----MAS-----Q-----------GTKIVADKLISDIQESAHDLIILPGGTAGAERLSKSRILKKLLKEQNSAGRIYGAVCSS-PAILHK------QGLLKDKKATAHPSALNKL-------------------KD---GAVN-----DAVVVIDGKVITSEGLATVTDFALAIVSKL-------- +-----------------------NGSEEIEVVTIVDILRRAKVDVVVASVEKSVQI-----LAS-----Q-----------GTKIIADKLIGVAAELTYDLIILPGGTAGAERLNKSRILKNLLKEQELAGRIYGAVCSS-PGILHR------QGLLKGKKATAHPSIVSKL-------------------TN---EVVN-----GTKVVIDGKVITSRGLSTVTDFALVIVSKL-------- +-----------------------NGSEEMEIIMLTNVLRRANVNVVLASVEKSTSI-----V------------------------------------------PGGPAGAERLHKSRVLKKLLREQKQTGRMYGGICSS-PVILQI------EIVDQDKTVTAHPSIVNQL-------------------MC---EVID-----RSKVVIDGNLITGMGLGTVIDFSLAIIKKF-------- +-----------------------NGSEEMEIIMLTDVLRRANVNVVLASVEKSTSI-----V------------------------------VLISLCVSLDIFKGGPAGAERLHKSSVLKKLLKEQKQTGRMYEAGFTP-GDILGI------EIVDQDKTVTAHPSIVNQL-------------------TC---EVID-----RSKVVIDGNLITGMGLGTVIDFSLAIIKKF-------- +-----------------------NGSEEMEVVTIVDILRRANVNVLVASIEKTTQI-----TAS-----Q-----------NTMIVADTLIDATLDSTFDMIILPGGLTGSTRLQKSKFLKKLLKEQKSGGRICGAIGSS-TAILQK------QGLLMNKTVVAHPSIIGTS-------------------KI---KSDE-----DIGVIIDGKVITSRGLGTAIDFSLAILYKL-------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASV------------GS-----Q-----------RMKIVADKSILSAFESKYDLIILPGGPVGAERLQKSKILQKFLEEQKQAGRMYGGISFS-PLILQK------QGFLQDKTVTAHSDIVNQL-------------------TC---QVMD-----RSKVVVDGNLITGKGLGTAIDFSLAIIRKF-------- +-----------------------NGSEEMEIIMLTDVLRRANVNVVLASVEKSTSI-----V------------------------------------------PGGPAGAERLHKSSVLKKLLKEQKQTGRMYGGICSS-PVILQK------QGLLQDKTVTAHPSIVNQL-------------------TC---EVID-----RSKVVIDGNLITGMGLGTVIDFSLAIIKKF-------- +-----------------------NGSEEMEVVMLVDILRRAKVNVVVASIEKTKQI-----IAS-----Q-----------KTKIIADTSIMDASKSTYDLIILPGGTAGVERLQKSRILKKLLREQMEAGRGYGGICSS-PTILHK------HGLLKDKIATAHPASIGKL-------------------TG---QVAE-----GVGVVIDGKTITSRGLGTVMDFSLAILDKI-------- +-----------------------NGCEELEIIILVDILRRAKINVVLASV------------GS-----Q-----------RMKIVADKSIMSASDSIYDLIILPGGPAGAEQLHRSRILKKLLKQQMQAGRMYGGVCSA-LKVLQQ------EGLLEDKTVTAHHAVASEL-------------------TC---QVID-----QPNVVIDGNLITGKGLGTVVDFALAIIRKF-------- +-----------------------NGSEEMEIIILVDVLRRAKINVVLASV------------GS-----Q-----------RMKIVADKSIMSASDSNYDLIILPGGTAGAEWLHRSRILKKLLKEQKQAGRMYGGICSS-LKILQQ------QGLLEDKIVTAHPDVANEL-------------------TC---QVID-----QSKIVIDGNLITGKGIGTAVDFALAIIRKF-------- +-----------------------NGSDEIEVVTIVDILRRAKVNAVVASVEKSLQI-----LAS-----H-----------GTNIVADKLIDVAAESIYDLIVLPGGINGAKRLSKSKVLKKLLKEQESAGRIYGAICSS-LTLLQR------QGLLKGKRITDHPSLSDKL-------------------KP---EVVA-----GAKVVIDGKLITSKGLSTATDFALAIVSKL-------- +-----------------------NRSDEMEIVVVVDVLRRAKANVVVASVEDSLEI-----VAA-----R-----------GTKIVADRLFKDAILSNYDFIHLPGGWYGAQKLGSTEQLIDLLREHAESNKAYGVVCAA-AVMLDT------KGLLKGKKATTHPHYSNKL-------------------SD---QSSV-----NVRVVIDGKLITSFGTGSTMEYALSIVEKL-------- +-----------------------NGSDEMEAVIPIDVLRRAKANVLVASVEDSLEI-----VAA-----R-----------GTKIVADKLMKDAFQSNYDLILLPGGLYGPERLRSSEQLVKLLKEQAESNKIYGGICLS-AVMLDT------EGLLKGKKATSYPKFTSKL-------------------SD---QSAV-----NARVVIDGKVITSQGPGTALEFAMAIVEKV-------- +-----------------------NGSDEIEVVTIVDILRRAKVNVVIASVEKSLQI-----LAS-----H-----------GTKIITDKFINVDAESVYDLIVLPGGLNGAKRLSKSKVLKKLLQEQKSAGRMYGAVSSS-LALLQK------QGMLKEKRIAAHPSISDKL-------------------GT---EVVD-----GAKVVIDGKLITSKGLATATDFALAIVSKL-------- +-----------------------NGSEEMEAVIIIDVLRRANADVVVASVEETLEI-----VAS-----R-----------KVKIVADKLIEDASSSAYDLIVLPGGMPGAERLSKTESLIQLLKEQAESKRAYGAICASPAVVLEI------HGLLKEKKATAHPAFTQKI-------------------AD---QSAV-----GTRVVIDGNLITSRGPGTTMEFALAIVDKI-------- +-----------------------NGSEEVEVVTIADVLRRAKVDVTVASVERSLRI-----TAS-----Q-----------GTKIITDKLIGEAAESSYDLIILPGGHACSERLKKSKILKKLLKEQQETGRIYGAANSS-STVLLK------HGLLKEKKTVVYPSDTDEP-------------------TN---DMIA-----GVEVVIDGNVITGLGLATVANFSLAIVSKL-------- +-----------------------------EVVTVADVLRRAKVDVTVASVERSLRI-----TVS-----L-----------GTKIVTDKLIGEAAESSYDLIILPGGHAGSES-----------------------TNSS-STVLHK------HSLLKEKRTAVYLSDTHRP-------------------VD---DMIQ-----GAEVVIDGSVITGMGLATVTNFSLAIVGKL-------- +-----------------------NGSEEVEVVTISDVLRRAKVDVTVASVERSLRI-----TAS-----Q-----------GTKIVTDKLIGEAAESAYDLILLPGGRAGSERLQKSKFLKKLLKEQQEAGRIYGATNSA-STVLHK------HGLLKEKRTAVYVSDTDGP-------------------AS---DMIE-----GAEVVIDGNVITSLGLATVTNFSLAIVSKL-------- +-----------------------NGSEEIEIVAIVDILRRAKVDVVVASIEKSVQI-----LAS-----R-----------GIKIVADKLIGDAAESVYDLIILPGGNAGAERLHKSKVLKKLLQEQYTAGRIYGAVCSS-PAVLHR------QGLLKDKRATAHPSVVTNL--------------------N---NVSN-----GAKVVIDGKLITSKGLSTVTDFALAIVSKL-------- +-----------------------NGSEEIEVVTVVDILRRAKVDVVVASVEKSLQI-----LAS-----R-----------GIKLIADKSIDNAAESIYDLIILPGGIAGAERLHKSKVLKKMLKEQGSAGRIYGAICSS-PTVLHR------QGLLKGKRATAHPSVASKL-------------------TN---EVVE-----GARVVIDGKLITSRGLATAIEFALAIVSKL-------- +-----------------------NGCEEIQVVTIIDILRRAKVNVVVASVEKSLQI-----LAS-----R-----------GTKIVADKTISVAAESVYDLIILPGGELSSEKLHKSRILKKMLKEQKSGGRFLGAICSS-PEILHR------QGLLKDKRATAHPSVISKL-------------------DD---VAVS-----GARVVIDGKLITAKGVANATDFALAIVSKL-------- +-----------------------NGSQGIELVTIADILRRAKVDVVIASVEKSLQI-----LTS-----T-----------GTKVVADKLIKEAVESTYDLIILPGGAAADERLNKSRILKKMLKEQDNAQRIYGAVCSS-PAVLFK------QGLLKDKRAVAHPSLETES-------------------T-----KVD-----TAKVIIDGKLITSKGFYNVIDFALAVVSKL-------- +-----------------------NGCEGIDIVTTIDILRRAKASVVVASVEKSTQI-----LAS-----Q-----------GIILVADKLINAAAEITYDLIILPGGVGGAERLHKSRVLRKLLKEQQIGGRIFGAMCSS-SAILQR------QGLLKDKKATAPESVLSKE-------------------S----NVVD-----GAQVVIDGKVIANKGLASATDFGLAIVGKL-------- +-----------------------NGSEEIEIVTIVDILRRAKVDVVVASIEKSVQI-----LAS-----Q-----------GTKIIADKLIGDAAESIYDLILLPGEIAGAQRLHKSKVLKKLLKEQDAAGRIYGAVCSS-PAVLHN------QGLLKDKKATAHPSVENQL-------------------SN---NVIN-----DAKVVIDGKVITSKGHATVTDFAMAIVSKL-------- +-----------------------NGCEDIEVVTIVDILRRAKVDVVVASVERHLQI-----LGS-----Q-----------GTKIVADKLIGEAAETSYDLIILPGGTAGADRLHKSRILKKLLKEQNLAGRVYGAICSS-PAILHR------QGLLKDKKVTAHPSVANHL-------------------AC---EGID-----GAKVVIDGKVITSRGLASVTDFALAIINKL-------- +-----------------------NGCEEVELVAIVDILRRAKAEVVVASLEKSRQI-----LGS-----K-----------GINIIADTVIRAAAETIYDLIILPGGISGTERLSKSRILRKLLKEQVSAGRFVGASCSM-PAFLQK------RGFLKEKRATAHPSVIGEL-------------------N----GAVN-----GAQVVIDGQLITSKGLSTAINLALTIVSKL-------- +-----------------------DGSEEMEAVMMIDVLRRAKVNVVVASVEKYMEV-----VAS-----R-----------NVKIVADMLISDAAKSTYDLILLPGGAKGAERLHKSSILKKLLNEQLLAGRAYGETCSASDGVLHR------HGLLEGKKAASHRSLSANI-------------------TD---AAKG-----GVGVVIDGKLITSRGTGATMDLALAIVSKL-------- +-----------------------HGSEEIEAVTLIDILRRAKANVKVASVEKTLEI-----SAS-----Q-----------GTKIVADVLISDAQESAHDMIILPGGIAGAQKLSKSRILKKLLKEQSSAGRIYGAVCSS-PAILHK------QGLLKDKKATAHPSVLDKL-------------------KE---EAIK-----DADVVIDGKLITSEGLATVTAFSLAIVSKL-------- +-----------------------NGSEEIEVVTLIDILRRAKVNVVVASVEKSAQV-----LAS-----K-----------GTKIVADKLINATSDSIFDLIILPGGAAGAERLHKSKILKKLLKEQESAGRIFGAICSS-PAVLQK------QGLIKDKKATAHPAVLDKL-------------------KD---G-VN-----DAQVVIDGKLITSQGLATAIQFALAIVSKL-------- +-----------------------NGSEEIEIVTIVDILRRAKVDVVVASVERSTQI-----VAS-----Q-----------GIKIIADKSISDAAESVYDLIILPGGVAGAERLQKSRILKKLLKEQKVAGRIYGAVCSS-PIVLHK------HGLLKAKKATAHPSVIGKL-------------------TN---EVVN-----GTKVVVDGKVITSRGLANVIDFALAIVSKF-------- +-----------------------NGSEEIEVVTIADILRRAKVDVVVASVEKSAKI-----LAS-----R-----------GTRIIADKLIRDAAESIYDLIILPGGNAGAERLNKSRILKKLLKEQKLAGRIYGAVRSS-PEVLHR------QGLLKDKKATAHPSVVSTL-------------------TD---EIVN-----GTKVVIDGKLITGRGLATVTEFALAIISKL-------- +-----------------------HGSEEIEVVTVVDILRRAKANVIVASVEKSLEI-----LAS-----Q-----------GTKIVADILIKDAQESAHDLIILPGGTAGAQRLSKSRILKKLLKEQSSAGRIYGAICSS-LAILHK------QGLLQDKRATAHPSVLDKV-------------------NE---EAIN-----GAKVVIDGNLITSEGLATVTDFALAIVSKL-------- +-----------------------NGCDVIEVVTIVDILRRAKVDVVVASVEKSVKI-----LSS-----L-----------GTKIIADKLIGDAAKSIYDLIILPGETAGAKRLQKSRILKKLLKEQDAAGRIYGAVCSS-ISVLQS------QGLLKDKKATAHPSFSSQL-------------------TN---EVVD-----GAKVVIDGKLITSKGLATVTDFAMAIVSKL-------- +-MSKKIAVLVTD------------QFEDIEYTSPVKAYEEAGYSVVAIDLEAGKE-----VTGKH----------------GEKVKIDKAISDVDASDFDALLIPGGF-SPDLLRADDRPGEFAK---------------------------------------------------------------------------------------------------------------------- +---MKVLIISAD------------NFEDTELLVPYYRLIEEGIEVDIASTRKG-N-----IKGKH----------------GYQIQVDKTLQEVNPDEYDMLILPGGSAP------------------------------------------------------------------------------------------------------------------------------------- +-SGKRIAILAEE------------WFEDSEIIEPMRAMKNADVRVAIVGSGSE-T-----YTGKR----------------GNAVRVDTTADKVSAEDFDGIIVPGAMLPTRCACTSP-WLI------------------------------------------------------------------------------------------------------------------------- +-MKKKVAILATN------------GFEEIELTSPKKALEDAGATVHIISPSGESW-----NDGNW----------------SETYKVDHAVSDVSASDYNSLMLPGGVLNPDQLRQDDASIGFIK---------------------------------------------------------------------------------------------------------------------- +-IMNKIAILAAD------------GFEEIELKSPKIYLQNKGFQVDIVSPKDEFW-----NHFDW----------------GPSYPIDVHLAEADPAVYEALILPGGTLSPDALRVLPKALDFIK---------------------------------------------------------------------------------------------------------------------- +--MKKIAIMLDD------------GYHDLELWIPYYRFKEEGIKFDILTWEDR-E-----YKGSF----------------GIDIKPDKLLGVTALSQYDLIYMPGAKSPVNLLKHPE-TVGQVK---------------------------------------------------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------------------------HLGESHKLKTIMHHIREQNKLYGAICASPVLALGP------LGMLNVKKATCYPSLENKF-------------------PA-HVQYV------KDCVVKSGNCLTSRGPGTAMLFALAAVTLL-------- +----------------------------------------------------------------------------------------------------------------AFAKSEKLVNMLKKQKESNRPYGAICASPALVLEP------HGLLKGKKATAFPAMCNKL-------------------SD-QSE-I------ENRVVVDGNLITSRGPGTSMEFALAIVEKF-------- +-----------------------------------------------------------------------------------------------------------------MSSNEKLVTLLKKQAAASKPYGAIGAATAHVLEP------HGLLEGKKAADQ--------------------------DG-GDE-C------ESRVVVDGNVITSGGTGTAMEFAVAAVEKL-------- +---------------------------------------------------------------------------------------------------------------------------MQAQRDGGRLSAAICATPAVFLQA------KGLLDGKKATAHPAFADKL-------------------VD-QSA-V------AQRVVVDGRLTTSRGPGTAFEFALELVKQL-------- +----------------------------------------------------------------------------------------------------------------RLRDNEILQRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKGRKITCHPSFIGDL-------------------PT-FRA-V------ESNVQVSGELTTSRGPGTAFQFALSFVEQL-------- +----------------------------------------------------------------------------------------------------------------KFASTDKLVDLLKKQAGSGKPYGAICASPAHVLEP------HGLLKGKKATAFPPMAHLL-------------------TD-QSL-C------ENRVVIDGNLITSRAPGTATEFALAIVEKL-------- +----------------------------------------------------------------------------------------------------------------RFASCEKLVNMLRKQAEANKPYGGICASPAYVFEP------NGLLKGKKATTHPVVSDKL-------------------SD-KSH-I------EHRVVVDGNVITSRAPGTAMEFSLAIVEKF-------- +----------------------------------------------------------------------------------------------------------------RFASCEKLVNMLNKQAEANKPYGGICKSPVYVFEH------NGLLKDKKATTHPRVSNEL-------------------SD-QSH-I------DHRVVVDGNVITSRAPGTAMEFSLAIVEKF-------- +----------------------------------------------------------------------------------------------------------------AYAKSDKLIGLIKKQAEANKLYGAICASPAIALEP------HGLLKGKKATSFPGMWNKL-------------------SD-QSE-C------KNRVVVDGNLITSQGPGTSMEFSLAIVEKL-------- +-----------------------------------------------------------------------------------------------------------------MGESDAVRKAILAMNDAGKIVAAVCAAPGV-LGK------YGLLEGKTACSFPQHEKNL-------------------I---ATVV------REPVVVDGNIVTSRGLGTTMDFGLKLLELL-------- +------------------------------------------------------------------------------------------------------------------------------MNRDGKIVAAICAAPSV-LGK------CGILEGKKATCYPGFEDKL-------------------I---AEVV------SEPVVADGNVITSRGLGTSMEFGFELIKKL-------- +----------------------------------------------------------------------------------------------------------------------------------KRGIAAICAAPSV-LGD------LGFLKGKKAVCYPGFESRL-------------------T---AEVL------AVPVVTDGHITTSRGMGTAIAFALELTKRL-------- +-------------------------------------------------------------------------------------------------------------------------------HRSGRIVAAICAAAATVLVP------HDIFPIGNMTGFPALKDKI-------------------PA-E-QWQ------DKRVVWDAKLLTSQGPGTAIDFGLKIIDLL-------- +-------------------------------------------------------------------------------------------------------------------ANEKVIEAVKYSCENGKIVAAICAAPSI-LGH------LGILDGKKATCFPGFEKEL-------------------K---ADYT------GTHTVTDGNIITAKGAGCAIEFGHAIVSLA-------- +----------------------------------------------------------------------------------------------------------------MLQGDRHVQALIQHCYDEGRWLAAICAAPTI-LAN------LGFLDRRRAVCYPGMEELM-------------------G--SVVQK------GAPVVADGHIITGEAAGSSFPFGLKLVEVL-------- +----------------------ANGFEEIEALGVVDILRRADLDVDTVSVNETLEV--TSSR-G--------------I----KVMADKCFED--MDHYDMLIAPGGGG-AWVLRDDQRVTDLFKKYFEEDKYVAAICAAPMVLGKA-------GIVKGKNVTSYPGEEIE-----SY------------LKE--GNYKE------DAVVIDGKMITSRGPATAMAFAYALVE---------- +---SEALFIVSEE-----------GYWGEECIEPLTTLSDAGVDITVATPSGAPPVDERSVDPAEVGEETA-AHVTEVHETDDRLREPVALADADPAAYDAVVFPGGHGTEWDITQDSHARAAL----------------------------------------------------------------------------------------------------------------------- +-----------------------DGTEEIEAIAVADVLTRGGMKVTLAGVGRKLQ----NI----VT-----MS--Q----GTKVQGDIAIEACVDLNFDLIMCPGGPG-AQHLHDCAELITMLQKQKHQGRYYGGICAAPAVVLIP------HGLLDAGPATTYPSYGE---------------------KMKGVDYKP-----DERVVVNGKCVTSQGPGIAIEMGLKLVEL--------- +-----------------------DGSEEIESVTIIDVLVRAGAAVTVASVMPSASTASSWQ----VT-----CS--R----GVKLVADKGIDDCLGEEWDLIACPGGPG-AEHLRDSPALLTLLQRQDKAQRLVAAICASPAVVLHT------HGFLTGKRATCFPAERF---------------------VSSLARYEG-----EEGVVEDGHVVTSRGPGTTLRFALTLVDR--------- +-----------------------DGSEEIESVTIIDTLVRAGALVTVASVGPE------VE----VT-----CS--R----GVKIKADCKIAECEARDWDAVVCPGGPG-AVSLKENETLEAILRKQNSEGRIVGAICAAPAVVLAS------HGLLEGKQATCYPASVF---------------------QSKIPQLV------SEKVVVDQNLITSQGPATSMAFALQLVGS--------- +---LEILLVLTSQA-TMGDDPRLTGVWFEEQSTPYYALVDAGANVDIASIAGGEPVDPHSIASEGMNPPSVECFL-DDKVSMDKLEGSLKIDSIAPEGGAVMFLPGGHGTMWDLPGAGR---------------SSICCRALGLTA------------------------------------------------------------------------------------------------- +--MKKIIFIIP-----------PKDFRDAELLEPKQILEQAGISITIASKTAGTIV-----GAD---GA----------E----VTASLKADEVNPNNYDAIAFIGGPG-MVDFVDDEQFIDLANQFNFAKKIVAAICVAPMILANA-------GLLIGNRKKSYCHILE------------------------------------------------------------------------- +--MKKILVVETNQT-SYGQRAEATGLWLGENTEFVLAVQAASYQVDYVGPKGGYVPDPRSMKYA--DAASLALY--RQPAFRAALAQTMPPAAVRPQDYIAIYYAGGHGVMWDFPAD------------------------------------------------------------------------------------------------------------------------------ +-----------------------PGSEETEAVTTIDLLVRAGVKVTTASVDGDLTICSRGV----------------------KLLADAPLVSIADQPFNAIVLPGGMQGAECFRDSPLLVEKVRQTHLQGNIVAAICAAPALVLQH------HDLFPIGNMTGFPGLKEQI---------------------PANKWL------ERRVVARVNLLTSQGPGTAMEFALKLIDL--------- +-----------------------DGCEEMEAVITIDVLVRAGATVTVASVDG-ATVCSRGV----------------------KIQADKLVSDIQDEEFDLIAVPGGMPGAEHFRDCEVLVKMLKKQKDSGRLYASICASPAVVFEH------HKIIQGEPATCHPSF--QSRL-----------------TNQG-NVL-------ERVVQSGNLTTSQGPGTAFEFALVLVKE--------- +-----------------------NGTEEIEAVTIADTLVRAGAQVTIASVENQLQIASRGV----------------------RIVADKLISDCTNEQYDLIAIPGGAKGAEKLGSCEELITLLRQQQQSGKFIGAICAAPALVLAE------NGFLEDSRATCYPADQFLSKL-----------------KNPVDDED-------CPVVVDGQFITSQGPGTALHFSLTLVEK--------- +-----------------------EGFEELEAVAPIDILRRANIEVTVASLSQDRVKNGISVMAD------------------------VDLDALSTSSYDAIIVPGGPPAIGTLKKDKRVLELLQQQMSAGRVVSAICAAPSVLHEA-------GVLEGKKYTAHFSVES-------------------VVPK----LDK-----SSAVVVDGNLITSQGAGTGTQFGLALVE---------- +--GKTMLMICG----W--------DFEDFEIAVPVMEFIHRGTKIIIGTFTGATRARPPLLGLEVVQ----GNFGMPLQEIPESNYNIKKLTEIGMGEFDGLLIPGAFN-PWNMIEAGTPLEFIKKADAAGKILSYMCHGPIPVAAA-------DLVQGKKITGWLACKD-------------------AVTSMGGEFNA---DWA--VALDGNHVSGRTTPELPEFIDA------------- +--GKRVLVIAG----E--------DFEDIELAVPVMEYIYRGAKVILATFMPLMRSRPPMLGLDVVQ----GNFGMPLQEIPLSYYQITKLSGIDMKDFDVVLIPGAFC-PWNMIVSGKPVEFLKKAHDAGKIIAAICHGPIAVAAA-------DLVKGKKIAGWLACKD-------------------A----------------------------------------------------- +--PKKVLVPIA------------NGTEPMEAVITIDVLRRAGADVAVASVEPGAT----SVAASW----------------GIKLTADALLADLADDEFDLISLPGGMPGSSTFGECKVLEKMVKKHVEKGKLYAAICAAPAMTLGT------WGLLNGLKATCYPSFIDK----------------------LPSEVHAV----ESRVQIDGKCMTSRGPGTAMEYSVIL------------ +--PKKVLVPIA------------MGTEEMEAVILAGVLRRAGADVTLASVEDGL-----EVKASY----------------GTRIIADKSIAACADQVFDLVALPGGMPGSVRLRDNEILQRIMVRQAEEKRLHGAICAAPAVVLMP------WGLHKGRKITCHPSFIGD----------------------LS-TFRAV----ESNVQVSGELTTSRGPGTAFQFALSF------------ +--KKKVLVPVA------------DGTEEIEAVTVIDVLRRAGAEVVVCSVEDGRV----EVTCSR----------------GVKLVADVNVKDVAPNDWDLIAVPGGMPGAERIADHIKFDAVLKKHFMAGKLMAAICAAPAICFEP------KGFLEGYAATAHPAFVDE----------------------LGGSLLYA----DSRVVVDKTVVTSRGPGTALEWALCL------------ +----------------------------------------------------------------------------------------HLIDEVDPQDYAALVVPGGFHSGFDEAYCQPLRDLAKTIHRQGGIIATMCVGILPIAES-------GLLEGGEATSYAFSRS--------HDNL------GRLRELGCKSTS------GPIVVWNRIISCSGPAYSVDVASLLLA---------- +----------------------------------------------------------------------------------------MLLKDVDVNEYDALAIPGGFEEGFDEAYKDETLQLIRSFDQVHKPIASVCVAALPIAKS-------GILKGRTATTYHLRGG--------YRR-------DELASLGVILGD------EWMVVDDNIITSSCPKTAADVAFELLT---------- +----------------------------------------------------------------------------------------CQLNEIELDEFDALAIPGGFEENFEDAFSEEFLNVIRTFDRQNKPIACVCVAGLVVAKS-------GALKDRSGTTYHFEKS--------LRQ-------KQMREMGVQVKN------ERIVEDRNIITSSSPETALDVAFCLLE---------- +----------------------------------------------------------------------------------------ILLNDVCIDDYDALAIPGGFEEGFNDAFSEQAVSLIKEFNDCGKMIATICVAALALGNS-------GILKGKKATTYHLNNG--------HRQ-------KQLAEYGAIVVN------EPVVRTDNIITSYCPQTGPEVAFMLLE---------- +-----------------------HCFEECELTFPYLYFAARNATLDVIGPWWV--KDGKIASCEFVR---VTRY----------AKRSFDFKQALSQKYDALIVVGGIWSSTVVRNDGDAMELIRQQAASGRLLATVCSGSTVLINA-------KLIKGMQLTGSPSIAI-------------------DLENAGAKYLD------VPVVKTTNLITGRSPGGLDNLL--------------- +-----------------------HCFEEVDLTFPYIYLTSRGATVDIVGPSWT--VDRKIVSCQYVR---ANRV----------VSINKTFKEAYLLQYDALFIAGGAWSTATMRTDSDAISLIQKTYNYGNMIGTIDMSSSLLINA-------GLIKGKKVTGAPAIRQ-------------------DLENAGAEYRD------STVVRDLFIFSGRAPEDIAELT--------------- +------------------------GTEPMEAVITIDVLRRSGADVTVASAANRLS-----VQALH----------------GVKIIADASVSDVVNTAFDLVALPGGVPGVDNLRDSAVLEGLVKKHVEDGKLYAAVCAAPAVVLGP------WGLLKGLKATGHPSFMEKL-------S------------SYTT-SV------ESRVQLDGRVVTSRAPGTTMEFGVALVEQ--------- +------------------------GTEPMEAVIIADVLRRAGADVIVASVSASLS-----VLARH----------------DVKIIADALVSDVVGTSFDLVAIPGGIPGVENLRDCKVLEVLVKKHVEEGRLYAAVCAAPAVVLGP------WGLLNGLKATCFPTLMEKL-------A------------SYAATTV------ESRVQVDGKLVTSRAPGTTMEFAVALVEQ--------- +------------------------GTEPMEAVIIIDVLRRSGADVTVASSSANLA-----VQALH----------------GVKIIADASVSDVAATAFDLVALPGGLQGDENLRDCKVLEGFVKKHVEDGRLYAAVCAAPAVVLGP------WGLLNGKKATCYPALMEKL-------A------------AYVAATS------ESRVQVDGTVVTSRAPGTTMEFAIALIEQ--------- +------------------------GTEPMEAVITIDVIRRAGADVTVGSVEKQLL-----VDACH----------------GVKIIADALVSDFSDAAFDLIALPGGMPGATNLKTCGTLESMVKKQAADGRLYAAVCASPAVAFGS------WGVLKGLKATCYPSFMEQL-------Q------------SSDATAV------DSRVQQDGIVVTSRGPGTTMEFAVALVEQ--------- +------------------------GTEPMEAVITIDVIRRSGADVTVASVEKELR-----VDACH----------------GVKIVADALVADCKNTVFDLIALPGGMPGASNFKDCGALESLVKKQAADGRLYAAVCASPAVALGS------WGLLKGLKATCYPSFMEQL-------Q------------SCA-TAV------ESRVQQDGKVVTSRGPGSTMEFAVTLVEQ--------- +------------------------GTEPMEAVITIDVLRRSGAEVTVASVEKELR-----VDACH----------------GVKIVADALVGDCKDTGFDLIALPGGMPGATNFKDCAVLESVVKKQAAEGRLYAAVCASPAVALGS------WGLLKGLKATCYPSFMEQL-------S------------SCA-TAV------ESIVQQDGKVVTSRGPGTTMEFSVALVEQ--------- +------------------------GRSRWRPSSPSTWLRRAGADVSVASVDPGAQ-----VGGAW----------------GVKLAADALLDDLADAEFDLISLPGGMPGSSNLRDCKLLENMVKKHAGKGKLYAAICAAPAVALGS------WGLLNGLKATCYPSFMDKL-------P------------SE-VNAV------ESRVQIDGNCVTSRGPGTAMEYSVVLVEQ--------- +------------------------GTEPIEAAATADVLNRAGARVTVAT--DDLV-----VQAAY----------------GVKFVADGRVADLQGESFDLIALPGGMPGSVGLRDCKALEKMVKTHAENGGLYGAICAAPAVTLAY------WGMLKGLKATCYPSFMEKF-------T--------------EVIPV------DSRVVVDRNAVTSQGPGTAIEFGLALVEK--------- +------------------------GTEPVEAAATADVLNRAGARVTVATVADELL-----VEAAY----------------GVKLVADARVADLEGEAFDLIALPGGMPGSTNLRDCKVLEKMVKMHAEKGELYGAICAAPAVTLAH------WGMLKGLKATCYPSFMEKF-------T--------------EVIPV------NSRVVVDRNVVTSQGPGTAIEFALALVEQ--------- +------------------------GTEPIEAATTADVLNRAGARVTVAT--DDLL-----VQAAY----------------GVKLVADGRVADLQGEPFDLIALPGGMPGSVGLRDCKALEKMVKTHAEDGGLYGAICAAPAVTLAY------WGMLKGLKATCYPSFMEKF-------T--------------EVIPV------DSRVVVDRNAITSQGPGTAVEFALALVEK--------- +------------------------GTEPLEAVAMITVLRRGGADVTVASVEDKVG-----VDACH----------------NIKMVADTLLSDITDSIFDLIVLPGGLPGGETLKNCKPLENMVKKQDTDGRLNAAICCAPALALGT------WGLLEGKTATGYPVFMEKL-------A------------ATCATAS------ESRVEIDGRIVTSRGPGTTIEFSITLIEQ--------- +------------------------GTEEMEAVIVIDVLRRGGAHVTVASVGQEPK-----VTASR----------------GVKLVADAIVSECGDEKYDLVVLPGGMPGAEHLRDSKALEDITRGQAQEQRAYAAICAAPAVALES------WGLLNGLKATCYPSFVSKL-------S------------DP--SSA------ESRVVKDGLVVTSRGPGTAMEFALTLVEQ--------- +------------------------GTEPVEAAATADVLNRAGARVTVATADDRLL-----VEAAF----------------GVKLVADGRVADLEGEAFDLIALPGGMPGSANLRDCKVLEKMVKKQAEQGGLYAAICATPAVTLAH------WGLLKGLKATCYPSFMEKF-------T--------------EIIPV------NSRVVVDRNAVTSQGPATAIEYALALVEQ--------- +------------------------GTEPIEAVITIDVLRRGGADVTVASIEKQIR-----VDATY----------------DVKLVADSLLSECSDAVFDLITLPGGIPGATNFKNCQLLEKLVKKQVEDGKLYAAVCASPAVAFGS------WGLLNGLKATCHPFFMDEL-------K------------SSGAITV------ESRVHEEGNVVTSRGPGTTMEFAVALVEK--------- +------------------------GTEPIEAVITIDVLRRAGADVTVASVEKQLR-----VDACH----------------GVKIVADALISDCSQSVFDLITLPGGIPGAANLKNNGVLESLVRKQAADGQLYAAICASPAVALGA------WGLLKGLKATGYPSFMEQL-------A------------SSGANAV------ESRVQVDGKVVTSRGPGTTMEFSVALVEQ--------- +------------------------ATERIEAVTIIDVLRRAGADVTVASVEKQLR-----VEACN----------------GV-IISDVLISDCSKSDFDLIALPGGVLGAANLKNNEVLESLVKKQAADGKLYAAICASPAMAFGT------WGVLKELKATGHPLFMEQL-------A------------SS-AIAV------ESRVQVDGKAVTSRGPGTAMEFAVALVEQ--------- +------------------------GTEPMEAVITIDVLRRASADVTVASVEKQLR-----VEAGH----------------GVKIIADSLISDCSDAVFDLISLPGGMPGATNLKNSGALESMVKKQAADGRLYAAVCASPAVALGS------WGVLKGLKATCYPSFMEQL-------Q------------SS-ATAV------ESRVQQDGVVVTSRGPGTTMEFAVALVEQ--------- +------------------------GTEPMEAVITIDVLRRAGADVTVASVEKQLR-----VEACH----------------GVKIIADVLISNCSKSVFDLITLPGGMLGAANLKNSEVLESLVKKQAADGKLYAAICASPAVAFGS------WGVLKGLKATCYPSFMDQL-------A------------SS-ATTV------ESRVQVDGKAVTSRGPGTTMEFAVVLVEQ--------- +------------------------GTEPLEAAATADILNRAGARVAVATA-SELV-----VEAAH----------------GVRFAADGRVAELGTDELDLIVLPGGMVGSVNLRDCKQLEKMVRKHAESGRLCGAIGASPAVALAH------WGVLQGFRATCHPALLRQL-------G------------DDGVIAV------DDRVVKDRNVVTSQGVGTAIEFALALVEQ--------- +------------------------GTEPMEAVITIDVLRRAGADVTVASVEPGAT-----VAAAW----------------GVKLAADALLTDIADAEFDLISLPGGMPGSSTFRDCKLLENMVKKQVEKGKLYAAICAAPAMALGT------WGLLNGLKATCYPSFMDKL-------P------------SE-VHAV------ESRVQIDGKCVTSRGPGTAMEYSVVLVEQ--------- +----------------------------MEAVITIDVLRRAGADVTVASAEKDLR-----VDACW----------------GVKLVADALVADVATASFDLISLPGGIPGSDTLRDCGVLESIVKKQAEKGGLYAAICAAPAVALGS------WGLLKGLKATCYPSFMDKL-------P------------SDA-TAV------ESRVQVEGQVVTSRGPGTAMEYSLALVEK--------- +------------------------GSEPMEAAIIIDVLRRAGADVAVASVEPGTQ-----VAASW----------------GVKLAADALLADLAEADFDLISLPGGMPGASTFRDCKVLENMVKKHAEKGKLYAAVCAAPAVALGA------WGLLNGLKATCHPSCMNKL-------P------------SE-VQAV------ESRVQIDGNCVTSRGPGTTMEYSVVLVEQ--------- +------------------------GTEPLEAVVTIDVLRRAGAEVTVASAEEQLR-----VDVCH----------------GAKIVADALISDCADAAFDLVSLPGGMPGASSLRDCKVLEDLVKKQAADGRLYAAICASPAVVLGS------WGLLKGLKATCHPSLMEQL-------S------------SF-ATAV------ESRVQVDGKTVTSRGPGTTMEYAVTLVEQ--------- +------------------------GTEPVEAVVPIDVLRRAGAEVTVASVEKKLQ-----IDACR----------------GVKIVADALISDCADNVFDLISLPGGMPGATTLKDNKTLESIVKKQASEGRLYAAICASPAVALGS------WGLLKGKKATCYPSFREQL-------S------------AAAAIVS------DSIVEHDGNVVTSQGPGTAMEYAVALVEQ--------- +------------------------GTEPIEAIAPIDILRRAGAEVTVASIENQLQ-----IEVMY----------------GIKMVADALISDCTNTEFDLIALPGGLPGAANLGNCKILESIVKKQAENGKFYAAICAAPAVALGS------WGLLKGLKATCYPSFMEEL-------S------------SH-AIAI------ESRVQKDAKVVTSRGPGTSIEFAVALVEE--------- +------------------------GTEPMEAVITIDILRRAGAEVTVASVEKELQ-----IDAGH----------------GVKIVADALIDDCSHTVFDLISLPGGMPGATTLKDSATLRSMVEIQAADGRLHAAICAAPAVALGS------WGLLKGLKATCHPSFMEQL-------S------------SS-AIVV------ESRVQQDGKVVTSRGAGTTMEYSVTLVEQ--------- +------------------------GTEEMEAVIIVDVLRRAGSDVVVASVEKELQ-----IEASR----------------KVKIVADAFVSDCTENSFDLIALPGGMPGASSLRDCQALESIVKKHAAEGRLYGAICAAPAVALDS------WGLLKGLKATCHPSFMDKL-------S------------T-A-VPV------KSRVQQDGRVVTSRGPGTAMEFSLLLVEQ--------- +------------------------GSEPMEAVIIIDVLRRAGADVTVASVEKRLQ-----VDACH----------------GVKIVADALISDCADTGFDLISLPGGMPGAATLRDCGMLESMVKKHAADGQLYAGICAAPAVALGS------WGLMKGLKATCYPSFMEQL-------S------------ST-ATTV------ESRVQQDGKVVTSRGPGTTMEFSVSLVEQ--------- +------------------------GTEPLEAVITIDVLRRAGADVTVASVENHIR-----VDAAH----------------QIKIVADSLISDCADTVFDLIALPGGMPGATSLRDCAVLENIVKKQAADGRLYAAICASPAVVLGS------WGLLKGLKATCYPSFMEQL-------E------------ST-ATAV------ESRVQIDGQVVTSRGPGTTLEFAVALVDQ--------- +------------------------GTEPMEAVITIDVIRRSGADVTVASVEKELR-----VDACH----------------GVKIVADALVADCKNTVFDLIALPGGMPGASNFKDCGVLESLVKKQAADGRLYAAVCASPAVALGS------WGLLKGLKATCYPSFMEQL-------Q------------SCA-TAV------ESRVQQDGKVVTSRGPGTTMEFAVTLVEQ--------- +------------------------GTEPLEAVITIDVLRRAGADVTVASVEKELT-----VDACH----------------GVKIVADALISDCADVAFDLISLPGGMPGATTLKDCKTLENMVKKQAADNKPYAAVCAAPAVALGS------WGLLKGLKATCYPSFMEQL-------S------------SSA-SAV------ESRVQQDGKVVTSRGPGTTMEYAVALVEL--------- +------------------------GTEPMEAVITIDVLRRSGADVTVASVEKEIC-----VDACW----------------GVKIIADSFIFDASDERFDLIALPGGMPGSMALRDSEVLEAMVRKHVKDGGFISAICAAPAVALGS------WGLLKGLKATCYPSFMEKL-------S------------ADA-VAM------ESRVVHDGQTITSRGPGTAIEFALALVEH--------- +------------------------GSEPIEALITIDVLRRSGADVAVASVETQLR-----VDACH----------------GVKVVADALVSDCRDAVFDLIALPGGMPGATNLKESEVLESIVKKQASDGRLYAAICASPAVALGS------WGLLKGLKATCYPSFMEQL-------A------------PACAATV------ESRVQQDGKVVTSRGPGTTMEFVVALVEQ--------- +------------------------GTEPFEAVVMIDVLRRGGADVTVASVENQVG-----VDACH----------------GIKMVADTLLSDITDSVFDLIMLPGGLPGGETLKNCKALENMVKKQDADGRLNAAICCAPALALGT------WGLLEGKKATCYPVFMEKL-------G------------ATCATAV------ESRVEIDGRIVTSRGPGTTMEFSVALVEQ--------- +------------------------GTEPVEASVPIDVLRRAGADVTVAA--ADLL-----VEVMY----------------GVKIVADANVADCADASYDLVALPGGVPGAANLRGCGALESIVRRQVLKGGLYAAICAAPPLALGR------WGLLDGVKATAHPAFVENF-------P--------------EVTAV------DANVVVDGKVVTGSGPATAMEFALALVEQ--------- +------------------------GSEPVEACVPIDILRRAGADVTVASAGDALL-----VEAMY----------------GVKVVADALVADCADASYELVVLPGGIPGAENLGGCAALQGIVRRHAEKGGLYAAICAAPAMALAP------WGLLNGHKATAHPWFVEKF-------P------------PE-VTAV------DANVVVDGKVVTSRGPATAMEFALALVEQ--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----IEASY----------------GTRIIADKPIAACADQVFDLVAVPGGMPGSVRLRDNEILQRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKGRKITCHPSFIGDL-------P------------TF--RAV------ESNVQVSGELTTSRGPGTAFQFALSFVEQ--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----VEASY----------------GTRIIADKSIAACAHQVFDLVALPEGMPGSVRLRDNKILQRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKGRKITCHPSFIGDL-------P------------TF--RAV------ESNVQVSGELTTSRGPGTVFQFALSFVEQ--------- +------------------------GTEEMEAVILVNVLRRAGAEVTVASVEPQLE-----IQASG----------------GTRLVADTTISTCSYQIFDLVALPGGMPGSARLRDCEILKRITSKQAEEKRLYGGISMAPAVTLLP------WGLLRRKRTTCHPAFFDKL-------P------------TF--WAV------KSNIQVSGELTTSQGPGTSFLFALSLVEQ--------- +------------------------GTEEMEAVILVDVLRRAGAEVTVASVEPQLE-----VHASG----------------GTKLVADTRISTCSDRVFDLVALPGGMPGSAQLRDCEILKKITSKQAEEKRLYGGISTAPAVTLLP------WGLLKRKRTTCHPAFFDRL-------P------------TF--WAV------KSNIQVSGELTTSQGPGTSFLFALALVEQ--------- +------------------------GTEEIEAVVLVDVLRRAGAEVTLASVEQKLE-----VEASS----------------GTKLLADVLISKCADQVYDLVVLPGGMPGAVRLRDCVVLEKIMKRQAEDKRLYGAISMAPAITLLP------WGLLTRKRTTGHPAFFGKL-------P------------TF--WAV------KTNIQISGELTTSRGPGTSFQFALSLAEQ--------- +------------------------GTEEMEAVILIHVLRRAGAHVTVASVEPQLQ-----VEAAS----------------GTKLVADASISECSDQIFDLIALPGGMPGSARLRDCDALRIITCKQAEENRLFGAINAAPAVTLLP------WGLLKRKKITCHPAFFHKL-------P------------TF--WAV------KSNIQVSNGLTTSRGPGTAYMFALTLVEQ--------- +----------------------------MEAVIIVDVLRRAGADVTVASVEPQLQ-----IEASC----------------GTKLVADTSISSCSDQIFDLVALPGGMPGSVRLRDCAALQKITSKQAEERRLYGAICAAPAVTLLP------WGLLRRRQTTCHPAFMHKL-------P------------TF--WAV------KSNIQVSEGLTTSRGPGTSYVFALCLVEQ--------- +------------------------GTEEMEAVILAGVLRRAGTDVTLASVEDGLE-----VEASR----------------GSRIVADKRIAACADQ--------GGMPGSVRLRDSAILQRITVRQAEEKRLYGAICAAPAVVLMP------WGLHKRKK-------------------------------------------------VSGELTTSRGPGTTFQFALSFVEQ--------- +------------------------GTEEMEAVIVVDVLRRAGADVLLASVEKGLE-----IEGSS----------------GIKLVADVFVTSCISEVFDLIALPGGMPGSARLRDSLVLKQITSRHANGKRLFGAICAAPAVVLEP------WGLMKRKQMTCHPAFMHKL-------P------------SF--RAV------KSSIQVSGELTTSRGPGTACEFAMSLVQQ--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----VEASC----------------GTHLIADKLISACADQVFDLVALPGGMPGSVRLRDNKILQRITVRQAEEKRLYGAICAAPAVVLMP------WGLHRGRKITSHPSFIGDL-------P------------TF--RAV------ESNVQVSGELTTSRGPGTAFQFALSFVEQ--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----VEASR----------------GSHIVADKRIAACADQVFDLVALPGGMPGSVRLRDSVILQRITVRQAEEKRLYGAICAAPAVVLMP------WGLHKRKKITCHPSFIEDL-------P------------TF--RTV------ESNVQVSGELTTSRGPGTAFQFALSFVEQ--------- +----------------------------MEAVILVDVLRRAGADVLMASVETDLV-----VEASS----------------GTKLVADVGIDACADEVFDLVALPGGMPGSVRLRDCEVLRKITIKQAEEKRLYGAICAAPAVTLMP------WGLHKRKQITCHPAFMDKL-------P------------TF--RAV------KSNIQVSGELTTSRGPGTTFEFALSFVEQ--------- +------------------------GTEEMEAVIIAGVLRRASADVTLASVEDGLE-----VEASC----------------GSRIIADTHIASCADQVFDLVALPGGMPGSVRLRDSDILQRITVRQAEEKRLYGAICAAPAVVLVP------WGLHRRKKITCHPSFIGDL-------P------------AF--RAV------ESNVQVSGELTTSRGPGTTFQFALSFVEQ--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----VEASC----------------GSRIVADTHIASCADQVFDLVALPGGMPGSVRLRDSDILQRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKRKKITCHPSFIGYL-------P------------TF--RAV------ESNVQVSGELTTSRGPGTSFQFALSFVEQ--------- +------------------------GTEEMEAVILVYVLRQAGAHVTVASVEPQLE-----VEASG----------------GVKFVADTSINSCTNQIFDLIVLPGGMPGSARLRDSEVLRSITSKHAEEKRLYGAICAAPAVTLQP------WGLLKKKRITCHPAFMDKL-------S------------SF--WAV------KSNIQVSGELTTSRGPGTTFEFALSLVEQ--------- +------------------------GSEETEVVTLVDVFRGGGALVKVASVENDIQ-----IECSS----------------GVKFVADTFISDCESQIFDLVVLPGGMPGLERLQDCKVLRKITEAHAKEGRLYGSSSEASAVVLEK------WGLLKGC-------------------------------------------------QVDGMVTTSQGLGLTLDFSLSIAEQ--------- +------------------------GNDEIDVVTLIDVFSFAGASVTVASVERDLQ-----VECSS----------------RVKLIADKFISECASCIFDLVVLPGGIPGSERLRDCEVLEKICRAQAEEGRLYGAVGAAPAVVLET------WGLLKGRRATCHPSVMDQL-------S------------SA--VPV------ESLVQVDGNVTTAQGPAVTLDFALCLAEQ--------- +------------------------GTEEMEAVIMLHILRQAGAHVTLASVEPQLE-----VEASG----------------GVKLVADTLINSCADKIYDLIALPGGMPGSARLRDCEVLRSITSKHAEDKRLYGAICAAPAVTLQP------WGLLKKKRITCHPAFMDKL-------S------------TF--RAV------KSNIQVSGELTTSRGPGTTFEFSLSLVEQ--------- +------------------------GVEEMEVVILVDVLRRAGSDVTVASVETDLQ-----IEASR----------------RVKLVADMLISNCTEEMFDLVVLPGGMPGSSRLRDCEILQSITKKQAADGRLYGAVCAAPAVVLET------WGLLKGLRATCHPSFISQL-------S------------SS--LTV------GSRVQRDGIVTTSRGPGTTMEFALSFVEQ--------- +------------------------GTEEIEAVVLVDVLRRAGAEVIVASVEQKLE-----VEASS----------------GTRLLADVLITKCADQVFDLVALPGGMPGAVRLRDCGILEKIMKRQAEDKRLYGAISMAPAITLLP------WGLLSRKKTTGHPAFFGKL-------P------------TF--WAV------KTNIQISGELTTSRGPGTSFQFALSLAKQ--------- +------------------------GTEEIEVVVLVDVLHRAGAEVTLVYVEQKLE-----VEGSL----------------GTKLLADVLISKCSEQVFDLVPLPGGMSGAVRLRDCVTLEKIMKRQAEDKRLYRAISMAPAITLFP------WGLLIRKKTTGHPAFFGKL-------P------------TF--WAV-------------------------------------------- +------------------------GTEEIEAVVLVDVLRRAGADVTLASVEQKLE-----VEGSS----------------GTKLLADVLISKCSEQVFDLVALPGGMPGAVRLRDCGALEKIMKRQAEEKRLYGAISMAPAITLLP------WGLLTRKKTTGHPAFFGKL-------P------------TF--WAV------QTNIQISGELTTSRGPGTSFQFALSLANQ--------- +------------------------GTEEMEAVIIVDVLRRAGAEVIVASVEPQLE-----VEAAG----------------GTRLVADTSISKCANEVFDLVALPGGMPGSARLRDCEVLRQITSKQAEDKRLYGAICAAPAITLLP------WGLLRRKQMTGHPAFMDKL-------P------------TF--WAV------ASKIQVSGELTTSRGPGTSFEFALSLVDQ--------- +------------------------GTEEMEAVILVDVLRRAGANVVVASVEPQLE-----IEASS----------------GTRLVADTSISTCSDEIFDLIALPGGMPGSARLRDSEILRKITSKHAEEKRLYGAICAAPAITLQP------WGLLRRKQMTCHPAFMDKL-------P------------TF--RAV------KSNLQVSGELTTSRGPGTAFEFALALVDQ--------- +------------------------GTEEMEAVIMIDVFRRAGAAVTVASVEEHLV-----VEASG----------------GTKLVADALISACSDETFDLVALPGGMPGSARLRDSKTLQDITKRQADAKRLYAAICAAPAITLLP------WGLLKRKQTTCHPAFMDKL-------S------------SF--WAV------KTNLQVWGELTTSRGPGTCFEFSISLVEQ--------- +------------------------GTEEMEAVIIIDVLRRAGAAVTVASVESELE-----IEASA----------------GVKLVADTLISSCSNEVFDLVALPGGMPGSVRLRDCEILRKITSRQAEEKRLYGAICAAPAVTLLP------WGLLRRKQTTCHPAFTDKL-------P------------TF--WAV------QSSIQVSGELTTSRGPGTTFGFALALVEQ--------- +------------------------GSEEMEAVILVDVLRRAGAEVTLASVEQRLE-----VEFSG----------------GTRLVAAAFVSACSDQIFDLIALPGGMPGSARLRDCEILQKMTSKQAEEKRLYGAICAAPAVTLLP------WGLLRKKKTTCHPAFIDKL-------P------------TF--WAV------KSNNQVSGELTTSRGPGTSFEFAISLVSQ--------- +------------------------GTEEMEAVILADVLRRAGAEVIVASVEPQLE-----IEAAG----------------GIRLVADTNISNCSNEVFDLVALPGGMPGSARLRDCEVLRQITSRQAEEKRLYGAICAAPAVTLLP------WGLLRRRQTTCHPAFMDKL-------P------------TF--WAV------KSNIQVSGQLTTSRGPGTSFEFALSLAEQ--------- +------------------------GTEEMEAVVLIDVLRRAGASVTVASVEPQLQ-----IEASG----------------GVKLVADVPISECCDEVYDLVALPGGMPGSVRLRDCETLRNIMSKQAERKRLYGAICAAPAVTLLP------WGLLKRKQTTCHPAFFDKL-------P------------TF--WAV------KSSIQVSGELTTSRGPGTSFLFALSLVEQ--------- +------------------------GTEEMEAVIMIDVFRRAGAAVIVASVEEQLE-----VEGSS----------------GTKLVADDFIASCSSEVFDLIALPGGMPGSARLRDCKVLQQITCKQAEEKRLYSAICAAPAVTLLP------WGLLKRKQTTCHPAFNHKL-------P------------TF--WAV------KSNLQVSGELTTSRGPGTCFEFAVSLVEQ--------- +------------------------GTEEVEAVTMVDILRRAGAAVTMASVEEQLQ-----IEGSN----------------GVRLIADASISSCVDESFDLVALPGGMPGSVRLRDCNILQKITSKQADEKRLYGAICAAPAVVLEP------WGLLKRKQMTCHPAFMHKL-------P------------TF--WAV------TSNVQVAGEVTTSRGPGTAIEFALSFVEQ--------- +------------------------GTEEMEAAILIHVLRHAGAHVTVASVEPQLQ-----IEAAG----------------GTKLVADTSISECSDQIFDLIALPGGMPGSARLRDCDVLRKITCKQAEERRLYGAICAAPAVTLLP------WGLLKRKKTTCHPAFFGDL-------P------------TF--WAV------KSNIQVSGELTTSRGPATTYQFALSLVQQ--------- +------------------------GTEEMEAVILADVLRRAGAEVTVASVEQQLE-----VEAYG----------------GTRLVADTFISTCSTEIFDLVALPGGMPGSARLRDCEVLQKITSRQAEEKRLYGAICAAPAVTLLP------WGLLKRKQTTCHPAFIDKI-------S------------SF--RVV------KTNTRVSGELTTSRGPGTSFEFAICLVEQ--------- +------------------------GTEEMEAVIIVDVLRRAGAQVTMASVEPQLE-----VEASS----------------GTRLVADTSISNCSHQVFDLIALPGGMPGSVRLRDCEILKKITSKQAEEKRLYGAICAAPAVTLLP------WGLLRRKQITCHPAFTDKL-------P------------TF--WAV------KSNIHVSGEVTTSRGPGTSFEFALCLVEQ--------- +------------------------GTEEMEAVIIVDVLRRAGAEVTVASVEPQLE-----IEASG----------------GTKLVADTSIAACSNQIFDLVALPGGMPGSVRLRDCEILQKITRKQAEEKRLYGAICAAPAVTLLP------WGLTRKKQTTCHPAFMDKL-------P------------TF--WAV------KSNIQVSGGLTTSRGPGTSFEFALCLVEQ--------- +------------------------GTEEMEAVIMIHVLRRAGANVTVASVEPQLQ-----VEAAG----------------GTKLVADTDISTCSDEIFDLVALPGGMPGSARLRDCEVLRKITSKQADENRLYGAICAAPAVTLLP------WGLLKRKKITCHPAFFDSL-------P------------TF--WAV------KSNLQVSKGLTTSPGPGTTYQFALSLAEQ--------- +------------------------GTEEMEAVIIVNVLRRAGAQVIVASVEPQLE-----IEAAG----------------GTRLVADTSISTCSNEVFDLVALPGGMPGSARLRDCKILQQITSKQAEEKRLYGAICSAPAVTLLP------WGLLKRKQTTCHPAFMDKL-------P------------TF--WAV------KSNIQVSGELTTSRGPGTCFQFALSLSEQ--------- +-------------------------------------------------------------------------------------------------------FSGGRA-PEYIRYDQDLVRITRHFFETNKPVGCVCHGVEIPAYA-------GCVKGRRMATVPKCKF-------------------DLEVCGGTFVD------EPCVVDGNLVSGRTFH--------------------- +---------------------------------------------------------------------------------------------------------GGRA-PEYIRYDEDLVRITRHFFEENKPIACVCHGVEIPAYA-------GCVKGRRMATVPKCKF-------------------DLEVCGGIFVD------EPCVIDGNLVSGRTFH--------------------- +---AHVLVVLSDEAQLELKKGFKTGFYLNELMQPTKMLLDAGHTVTFATPKGKAPTDESSNNVMYFNQDEKKQYADHDLKLDSPVVSLSRIEQIGVGQFDAIYIPGGHAPMQDLLKDNSVHDK------------------------------------------------------------------------------------------------------------------------ +--MKKTAVLI------Y------ESYCNFEISVALEGLALKNKEIVVFAKRKDLFKSEEGL----------------------TVSPDKSIDEIIIDEYDSLLLPGATD-IRSAIEDKDILNFIKKFKNK--IIGAISIAPILLVKA-------DLLNGKPFMAGVNKEDLF---------EEG-FTAEELDKM-KGWNDCIKNVEDGYIITDKIVTSIAFN--------------------- +--MKKTAVLL------Y------ESFCNFEFSVLLEILAINKKPVVFFAKEILPIISEEGL----------------------KVIPDIKIEDLDISEFDSLILTGAAD-IRKAIEDEEILSFIKKFDERDYIIGAISIAPILLLKA-------GILSGKSFMAGVNKEELY---------EEG-FSKKDLTLM-IDWNESIKNVPNGYIKDRNIITSVSYE--------------------- +--MSKTAVLI------Y------DSFCNFEISVALEILALNNREIVVFAKDTEVVTSEEGL----------------------KILPDKDIYDIDIGEFDSLLLPGAAD-IEAAVEDEEIIEFIKKFNGK--IIGAISIAPILLVKA-------GMLNGKAFMAGVNKEDLL---------EEG-FLEAELVKM-KDWNECIENIEDGYILEDKIITSVSYN--------------------- +--MKKTAVLM------Y------GGFCNFEISVALEYIALKNREITVFAKSLDVIKSEDGL----------------------RVLPDKSIYEIDIDEYDSLLLPGAAD-IRDVIEDEDILNFIRKFDGK--VIGAISIAPILLLKS-------GLLSNKEFMAGVNKEDLF---------EEG-FTETELRKM-RDWNECVKNTKDGYVIDSNIITSVSFE--------------------- +--MKKTAVLI------Y------DSFCNFEFSVALESLSLSGKQITVFSKIKEPIQSEEGL----------------------IMQAEKTIYELNIDEFDSLLLTGATD-IRNTIEDESIIEFIKNFDGK--IIGAISIAPILLLKA-------GMLNEKSFMAGVNKEDLL---------EEG-FDETDLSNM-VGWNDNLQNVVDGYIIDDNIITSISYN--------------------- +--MKKTAVLL------Y------DSFCNFEISPALEILALAEKPITIFGISKQAIRSEDGL----------------------SVIPDATINNFDLDAYDSLILPGAMD-IREAIENKKIIDFIKKFDGK--TIGAISIAPLLLVRA-------GLLNGKPFMAGVNKEEIF---------EEG-FSESDLAEM-VGWDDNINKIKDGYIITGNIITSISYN--------------------- +--MKKTAVMI------Y------RAFCMQEISCLTDWLVGL--PMIVCAADHQPVKTEEGF----------------------TVLPEFSYDEVNLDEIDCLILPGISE-FPEVLK-QRQLDFLARFKEPDILIASISVSPVLLAAA-------GLLEGICYCGGFYQEVLD---------DLP-FM-------------EKENRFEPIVVEGNIMTAFGGA--------------------- +---MTTAIIL------Y------PGFSEYELSAVISVLTQANHPKVFIGLDDEPVIGEAGL----------------------SCNPDISLNEAEISQYQSLILPGVDD-FKHLLA-DDLFSFIWSGY-QDAVIAAISSAPYLMAKS-------GILDDRSYTAGISKQSRE---------FLG-VF-------------NEERVDAPYVFDRGILTAKGNA--------------------- +--QTYTGILL------Y------PGFSEYELSVLLSVLQQGGQQKMYIGLDHQVVKGEAGL----------------------SCVPYTTINEVDFEQIDSIVLPGVDD-FEHLVN-RELSAFLNKIN-QQKVIAAISSAPYLLSMS-------GVLSGVKYTTGLTVDQRM---------FLG-TF-------------DEADVDEPVVTDQRFITARGAA--------------------- +--MRKTAVLL------Y------PQFSEYELSVALSILRQGKKPIMTIGT-GLEIRGESGL----------------------LCKPDRLLSEVDVDEFDSLLLPGCLD-IGALVN-YALIHFIKEIS-RENWIASISSSPYLLALA-------GALQGKEYRICLPQSFIQ---------SSE-HL-------------DAQLRDVPVVQDNHIITAIGSG--------------------- +--MKKTAVLL------Y------PQFSEYELSVALSILMQGGKPIITLGSNTKPIRGESGL----------------------NCIADLSVNEIELDDIDSLLLPGCMD-ISTLQL-ESLLDFIRYLS-KGGMIASISSSPYLLAKA-------GVLKNKKYTVGLPFDGMK---------QLG-CF-------------ELHNSDELVVQDGNIITARGRG--------------------- +--MKKTAILL------Y------PQFSEYELSVALSILMQGNKPVITVGLNNEKIKGESGL----------------------SCIADTQISEVNLDEIDSLLLPGCMD-IALLIN-QKLIDFIGNAN-KGAIIASISSSPSLLAKA-------GVLKNKKYTVGLPPEGIR---------KLD-FF-------------DLNHSEDLVVQDGNIITARGRG--------------------- +--MKKTAILL------Y------PQFSEYELSVALSILMQGNKPSVTVGLNHQPIKGESGL----------------------SCLVDSSVDEIKFSEFDSLLLPGCMD-VMTFIK-PKLTEFVKQVN-SETVIASISSSPLLLAKA-------GLLRGRKFTVGLTEEAIE---------NLG-VF-------------EKENSEDVVVKDGNIITARGRG--------------------- +--MKSTAILL------Y------PQFSEYELSVALSILMQGGKPVRILTSDGNPVRGEAGL----------------------KVMPEQSIMEAKKSEFDSLLLTGCMD-IFQLEA-ETIFSFIKEFH-SGAVIASISSSPFLLAKA-------GVLEGKRYTIGMTEEKRQ---------KAG-VF-------------DHSLRDELVVTDGKIITARGRG--------------------- +--MKKTAVLL------Y------PQFSEYELTTALSILMQGGKSISVIALTKEGVKGEAGL----------------------TCVADETIDQVNYQEFDSLLLTGCMD-IASVVE-EKYIEFVQKIANANFVIASISSSPMLLAKA-------GLLKGKKYTVGLLAEHRE---------QCG-LF-------------DDANVEDLVVQDGNVITAWGSG--------------------- +--MKKTAVLL------Y------PKFSEYELTVALSILMQGKKPVVTIGLNDRPVRGEAGL----------------------TCIPDTTIDQANQAEIDSLLLTGCMD-VLALQN-ADLIEFIRKTG-NASVIASISSSPFLLAKA-------GLLQGKKYTIGMTEENRK---------KTG-VF-------------EAENSGEPVVRDGNLITATGRN--------------------- +--MKKTAVLI------Y------PQYSEYELSVALSILMQGEKPVITIGLNNLPIRGESGL----------------------TCLTDTTIDEVNLEEIDSLLLTGCMD-ILALEG-KEIFEFISRIE-KATVIGSISSSPYLLANA-------GLLNGKKYTIGMTEENRE---------KSG-VF-------------EKENSEELVVQDGKLITARGRG--------------------- +--MKKTAVIL------Y------PQFSEYELSIALSILMQGNKTMVTVGLDNHSIRGESGL----------------------TCVADTTIREINIEEIDSIVMPGCLD-IKTLLN-EILFEFLKLAV-KETIVASISSSPYLLAKA-------GLLTGKKYTVGLPMEAIE---------KLC-VF-------------DKEKCDDLVVQDGNIITARGRG--------------------- +--MKKTGVLL------F------PLFSEYELTVALSILKQGNKPITTIGITAEPIFGESDL----------------------KCLSDYTIYDVDIETLDSILIPGCMD-ITTLFD-DDLIEFIRRCVESEVIIGSISSSPYLLAKA-------GILENRKYTIGMHEAGRS---------QTG-VF-------------NEENCDDLVVQDGGILTARGRA--------------------- +--MKQIAVIL------Y------EGYCLCEITVALEMLRMADIPVTYFGVEKKAYRSEEGI----------------------VLQCEHTLDELDVDGYDGILLSGFME-ENPTILKELLKEKLRTFDQQKKVIGAISIAPLLLYNA-------GILKDRPFMCAMNKQDLV---------EEG-YALSCLQNM-IDWDACCAE-DLKFIRHEHIITSVIYG--------------------- +---MKAAVCL------Y------DGFCNFEFSVLLESLALADCQIDYIAKTLKPVRAEEGF----------------------LALGEYTWGTICADDYDVLVLTGIGA-ESDWILAEELLSLIRSFDKAGKLIAAISCAPMILVNA-------GIMNERRYVASVDRECFM---------AGG-ACAEQMKGL-LDMKEQKKHELHGYVQDGNVITANGWW--------------------- +--MNKFAFIA------Y------DDFAIWQVALLQKFLKDKSWKMETFSIDGSNVSTDGGI----------------------VINVEKSIETEDPNEYDLILLPGGNV-TSSLIE-QPLRTFLRCYKG---NIAASCASAVLLAAS-------GLINGKYTCMPQTNDQ-----------YSH-LF-------------RNGNDGSDVCIYKNIITSKGPA--------------------- +--MKKIGFIV------Y------EGFAIWQVSLMQMFLKQDGWEINTLSVDGGLVATDGGI----------------------YVDSE-ILDNKDPKEYDLILLAGGEI-NESLLD-QTLIDFLQEYDG---IIAASCASSMILGSA-------GLLDCEYTTMPHIHAI-----------YNE-YY-------------EDGTVDTDLCVTDRIITSRGHA--------------------- +--QKKVGFFV------Y------DDFAIWQVSLLLKFLTDADYQIETLSINGGLVSTDGGV----------------------LVHTE-SIGHKNPNEYDFLLFPGGRV-TKELVD-QHLKQFLQEFNG---FIAASCASSAIVAGA-------GLVKGDFTTMPPIKEI-----------FSE-YF-------------TEGNTDTDIVVGEKLITSKGSA--------------------- +--MKKVACVI------Y------PNFSLYEIVDLTSSLVLQGIKVDYISSNKESVISEDGL----------------------ICQATKTFDEVNLDDYSCVVLPGMSD-FTFALK-NTLIQFLKQLKGKSILVAAISSAPILLSKA-------GLLENTTFTGGIWQNFFG---------YFD-FL-------------SRENIPKAIHQDKNIVTAIGFA--------------------- +--MKKI--------------------ACYEIAPLTSALVLNGRKIDFIASTKETIYSEDGL----------------------ACHANKTLDEVNVEEYDCILCPGMID-FTQALR-ECLIRFLAGLDGKSIKIAAISSAPILLAKA-------GLLKQTLYTGGIWQNFID---------YFD-FL-------------PRENRPLPVCEDGNIITGTGFT--------------------- +--MKKVLCLI------Y------PNFSLYEVVGLTSTLALSGVEVDYVGTDRNVITSEDGL----------------------PCQPTRTLDEVVIEDYSCVILPGMIN-IAPALH-EKLISFLKNLKQQEIFIAAISSAPILLAKA-------DLLNDTRFTGGIWQNFFD---------YFE-FL-------------PRENKAQAVLQDKNIITAVGFA--------------------- +--MKKVLCVI------Y------PNFSLYEITTLTSTLALSDITIDYVASENSMVVSEDGL----------------------PCQPTKTLDQIRIEDYSCVILPGMVN-IGSALQ-EKLISFLRSLNEQDILIAAISSAPLLLAKA-------GLLNNTKFTGGIWQNFFD---------YFE-FL-------------PRENQPKVLVQDKQIITAIGFA--------------------- +--MRKGAVVV------Y------PQFSMQEISCLTELFKFY--EITVFASSLKPVNSEDGF----------------------TILPHKTFSDFQRDEYDCIILPGIWD-FREALE-NKNIGFLRQFVNNDIIIASISSSPILLAKA-------GILDNHKYCGGLFEEVID---------EYD-FI-------------PRKNVRKPVCVDTNLVTAIGFA--------------------- +--MKKVACVI------Y------PNFSLYEIVDLTSSLVLQGIKVDYIAANKENILSEDGL----------------------ICQATKTFDEVELNEYSCIVLPGMSD-FTSALK-ELLIQFLKQLKGKSIVIAAISSAPILLAKA-------GLLEDITFTGGIWQNFFG---------YFD-FL-------------SKENMPKTIHQDKNIITAIGFA--------------------- +--MKKVACLI------Y------PYFSLYEVTALTSTLVLSGVDIDYIATSKDLIVSEDGL----------------------SCQATKTLEQISIDDYSCLILPGMID-FKPALR-KELLTFLAGLNEESILIAAISSAPILLAKA-------GLLKDKTFTGGIWQNFFD---------YFD-FI-------------PKENKPLSVLKDQNIVTAIGFA--------------------- +--MKKVLCII------Y------PNFSLHEITALTSTLALSDITIDYVASDYSIVISEDGL----------------------PCRSTKTLDQVRIEEYSCVILPGMVN-IGPALQ-EKLNSFLRELGKQDILITAISSAPILLAKA-------GLLNDTKFTGGIWQNFFD---------YFE-FL-------------PRKNKAKAVLQDKNIITAIGFA--------------------- +--KQKVAILI------Y------PEFSNYEISILAEIFKLF--EIVVFSAEKNIVNSEEGF----------------------HFMPDKSLDEFNINEYSCLVLPGMWS-FPKVLN-NRYINFLEKFRDKDIIIASISSSPILLARA-------GVLNKKKYCIGLYEEDID---------KYD-FL-------------DRESLKEPIVEFDNIITALGLA--------------------- +--KNKALVLV------Y------NGMSLSEITLLTDYLTVFWWDIDTIGSNKEMIKTEDSF----------------------QIVPNKSFNEINFEDYNLIILSGIMN-PYPIAE-KALIEFLKPLKKNRPLIASISSSPMLLAKS-------GILEGVKFTSGLFEETLN---------EFD-FF-------------EKKNIRQPVVYDNNIITAIGFA--------------------- +--MNKILVMI------Y------DGFSMYEISPLTSILAWSDWQIDVVAVEHKPYQTEDGF----------------------EVIPQMTFEDVQNIAYQMLVMPGIAN-YHTVLP-QRNIAFLSRFKTPRPVIAAISASPILLAKA-------GLLDDTKFVAGLFESAYE---------EER-FI-------------PKRNVRKPVVSDNGIVTSTAFF--------------------- +--IKQALVML------Y------PGFCYFEVAALTEILAFKEWTVTTVGADRQNYLGEDGL----------------------QVLAEKSFSQVDPLAVDLMILPGIDN-YHVPLA-SRNVAFLRQLNTSRPIIAAMSSSPVLLAKA-------GLLDQTQFTGGLFEETYA---------KNP-FI-------------PKQNVRQPVVVDNGIITSSFQF--------------------- +--------ML------Y------PGFCYYEIALLTETLAFTNWQMTTVAADSNLSESEDHF----------------------KIKPDKLLSQVDPLDYQLLILPGIDD-YHIPLA-PQNIDFLKKLYCKRPLIASISSSPILLAKA-------GLLDDTKFMTGLFEEAYE---------QNP-FI-------------PKQNVRKPVVTDNGIVTASGQF--------------------- +--MKHFLVML------Y------PGFCNFEITALTEILAFQDWETTTVAAARKAYTGEDGM----------------------AVLAQKDFSQVDPLDYELLILPGIDD-YHVPLS-ERNVAFLARLKTKRPIIASMSSSPILLAKA-------GLLADTKFTGGLFEETYE---------KNS-FI-------------PKQNVRQPVVSDNGIISSSFQF--------------------- +--MKKFLVML------Y------PGFCYFEVSALVEALAFEDWTMTTVGAERRLYESEEHL----------------------QVMAQTDFSQVDPLKASLIILPGIDN-YHVPLD-ERNVAFLRRLDTHRPVIAAMSSSPVLLAKA-------GLLTQTHFTGGIFEETYA---------KNP-FI-------------PKQNQRQPVVIDNGIVTSSFQF--------------------- +--MKRSLVML------Y------PGFCNFEISALTEILAFQDWSLTTVGADRQLYEGEDHL----------------------QVMAQKDFTEVNPLDYDLLILPGIDN-YHIPLE-PRNAAFLAQLNVKRPIIAAMSSSPVLLAKA-------GLLDHTKFTGGLFEETYE---------LNS-FI-------------PKENIREPVVSDNGIITSSFQF--------------------- +---MKIGLII------Y------PEFSLYEITPLTAQLALNHQQVDIIAEEKKCYVSEDGF----------------------QVMPEFAFSQVKWTDYDALFFTGTMK-PFETVL-ATMIENLALINSETTVIAAMSSSPLILAKA-------GLIKDRTFTGGIYTNLLS---------YFS-WL-------------NEDKMDKHCVVDGKLITALGRG--------------------- +---MKVALII------Y------PEFSLYEVTPLTATLAINDISVDIIASEMTVIKSEDNF----------------------QVMPHFSLDQINLATYDTILLTGTMA-AFEILK-QKLLSELSKINLNKTTIAAISSSPLFLAKA-------GVLSGHRFTGGIYSNFLD---------YCT-WL-------------EKENTGAHYYQDRNIITAVGSG--------------------- +---MKIALLI------Y------PEFSLYEITPLTASLALQNEKVDIIASQKKLHKSEDGF----------------------QVMPHYSIDEIDLTTYELILLTGTMD-PFFAVN-VNLINTLSKISLEDTVVASISSSPLLLAKA-------GLLDTYKFTGGIYRNYFN---------SFT-WL-------------KESNLPRLCTIDRNLITAIGMA--------------------- +---MKIALLI------Y------PEFSLYEITPLTAKLTLEQEKIDVIASQKSIYRSEDGF----------------------QVIPHFSLHEIDLSSYDLILLTGSMA-PFSAVN-VTLIDAISKVSLTKTVIASISSSPLILAKA-------GLLDDYDYTGGIYRNYFD---------TFL-WL-------------NKSRQPRVCNIDRNLITAVGEG--------------------- +---MKIALLI------Y------PEFSLYEMTPLTAKLTLQQQKVDIIASKKILYQSEDGF----------------------QVMPHYALEEIDLARYELILLTGTLD-PFVAVN-LNLIKALSKVSLENTLVASISSSPILLAKA-------GLLNNHLYTGGIYRNYFN---------SFS-WL-------------KASNVPRLCMIDRNLITAIGKA--------------------- +---MKIAVLL------Y------PACSLQEITTLTSTLCLPGQSLDYLASEKKVYTSEEGL----------------------QVIPDFTFAEVQNVKYDCIILPGTLE-PFVSLY-FRLISFLKRVDTKRTIVAAISSSPMFLGKA-------GLLRSRYYTGGLYMELVE---------YFS-FL-------------EKENLHQPVVKDKNVITAIGFT--------------------- +--MSKFAVIL------Y------PDFSLQEITCLTSALSVWEEKIDFIASENREYCSEEGL----------------------RVMPTKTIADVNITDYKCIILPGTIN-PLPALY-DRLIEFLRGGINTDVTFAAISSSPILLAKA-------GVLDGRKFTAGFFMQMAE---------TFS-FV-------------ENENIHKGIVCDGNVITGIGMF--------------------- +--MTKFGVVL------Y------PNYSLQEITCITSTLSIWNEEIDYIASENICYFTEEGL----------------------PTYPTKLIHEVNITDYDCIIIPGSIN-PLVGLY-DELIHFLHQGISSNIVFAAISSAPLLLGKA-------GLLKGKKYTGGLFVQQLD---------YFD-FM-------------EIDNTHKSIEIEDGLITGIGMY--------------------- +--MKKFAVIL------Y------PDFSLQEITCLTSALTVWGEKLDFIASEDQEYLSEEGF----------------------VIRPTKIIGNIKAKNYDCLILPGTMN-PLPALY-EKLIDFLREGIDFGTVFAAISSSPILLSKS-------GVLKDKKFTAGYFMQMTD---------TFD-FI-------------EKENIHKGIVEDKNVITGIGMF--------------------- +--MKKFAVVL------Y------PNYSLQEITCITATLAIWNEKIDYIASENSCYLTGEGL----------------------PTYPTKLIQEIEITDYDCIIIPGSTN-PLSGIF-DTLIEFLSKGKGGPTVFAAISSTPLLLGKA-------GLLEGKRYTGGLFMQQIA---------FFD-FM-------------EKENTHEPVETDERLITGIGMY--------------------- +--MRKFAVML------Y------PDFSLQEITCLTSALTVWGETIDFIASENKEYRSEEGL----------------------RVFPTKTTADAAITDYDCVILPGTIN-PMPALF-ETLIDFLRGGVNTSIVFAAISSSPALLSKA-------GILDGKKFTAGYFMQFAD---------TFS-FI-------------QKENVHKPIVEDGNVITGIGMF--------------------- +---KSALIIC----GDYME--------DFEVMVPFQVLQAFGVRVDCVSPTKLPGQKCFTAIHVSLG-F-EHYSELPGHLF--TLN--SNFNEVEVGCYDALVIPGGRFS-ELFSVDERVLSIVKAFAEAGKPIVTTCHSQLILAAA-------GLLKGKKCTAFASMKP-------------------VIELAGGIWWQPTSPFDIACLKDGNILSSIGWPAHAEI---------------- +--------------------------NDLHATVPCFLWRKARYAVDLISAEAKAS---IMLEMG----------------I--HVRCDNTLSKTNFNQYTAAFIPHGNT--TRLVEIDKLRKDLEKFVKPMRWLFSSGNGACVLK-E-----FDLIAPDQLVTVQNEKEM--------V------------KLLGKNFIK------QPVHVDKNIISCANSCGLTKFSFKVI----------- +--------------------------EDMELLVPVDIWKRANFIVDVIVYNTKTS---FSLNSG----------------L--RVSSSLKIKDINMVQYDAIFLPGGPK--WKDTSDPKLHVTLEKFFNPEKWIIAICGAPAALMCL-----D-EKARDIKYTCYNSPEV--------I------------GDFTQNWLN------KKVVIDKQIITGQNAGCSMELAFAVI----------- +--------------------------EDMELIVPVDIWKRAKFIVDVIVYDTKTS---FSLNSG----------------F--RVPSQLKIKDINMIQYDAIFLPGGPR--WKNVKDPKLHVTLEKFFNPEKWIIAICGAPSALMCL-----GDEKAKDIKYTCYNSPEI--------I------------GDFTENWLN------KKVVIDKQIITGQNAGCSMELAFAVI----------- +--------------------------EDMELIVPLDIWRRAKFAVETISCEVKNS---ASLNSN----------------L--KISTNLKLKLTNLDQYDVLFFPGGPG--FKALNESKLHTTIKKFYKENKWLVSICAAPAALVTL-----ERELDDKTRFTCYNDIKL--------T------------RDYSKLWVN------KPIVVDNKFITAQAAGCALALAFLVV----------- +--------------------------EDMEFIIPFDIWRRAKYVVETISCEVKNV---ASLNTD----------------I--KFTSNLRLKLTNLDQYDLLFFPGGPG--FRAMGESKLHLAVKKFYKENKWLVAICAAPAAIMSI-----EREWDPDIKFTCYNDPRL--------I------------GDYSKLWVD------TPIYVDKKFITAQAAACSLPLAFLVV----------- +--------------------------EDMEFIIPFDIWKRAKYIVDTISCETKNA---ASMNSN----------------I--KIAADLNLSLTNLDQYDMLFFPGGPG--FRSIGEAKLHSTIKKFYKENKWLVAICAAPIALTTL-----EKELEEDFRFTCYNDPKL--------I------------GDLSPKWLD------QPIHFNRKVVTAQAASCATQLAFTIV----------- +--------------------------EDMEFVIPFDIWRRAKYVVETISCEVKNS---ITLNTD----------------I--KFSASSNLQLTNLDQYDLLFFPGGPG--FRSVGESKLHLAVRKFYKEDKWLVAICAAPVAVISV-----ERDWEPDIKFTCYKDPKL--------I------------GEYSKLWVD------TPVHIDKKLITAQAAACSLQLAFLVV----------- +--------------------------EDMEFIIPFDIWRRAKFVVETISCEVKNN---ALLHSN----------------M--KISANFKLKLTNLEQYDLLFFPGGPA--FRALGESKLHTAIKKFYKPDKWLVSICAAPISLLTL-----EGELHENFKFTCYNDSKL--------I------------GDYSKLWVD------KPVVIHRQFITAQAASCALQLAFLVV----------- +--------------------------EDMEFIIPFDIWRRAKFVVETISCEVKNN---ATLHSN----------------M--KITTNFKLKLTNLEQYDVLFFPGGPA--FRALSESKLHTTIKKFYKPDKWLVSICAAPISMLSL-----ERELHPDTKFTCYNEPKL--------I------------GDYSKLWID------KPIVIDRKFITAQAASCATQLAFLVV----------- +---GSILMVVAP-----------KNYQERELNIPKEAFERSGLDVDVASK-GVTTA--TSMSGES-------------------VAIDVDVRNADLSKYRAVVFVGGIGVELNLHKDSDYVNLAKSAHDKGIIVAAICLAPNILASA-------GLLANKNATCADST---------Y-------LV-----QKNVNYID------APVVRDGTIITGRDPDASAEFAETIVSA--------- +----------------------KFGTWASELTVVAGVLLKAGYKVKVATEDGMPPHLSPSLDPTFQDGAWERRFLDPNSALLSQLPKPPQVGDQLANAYDAIVIAGGSGAIPGLMADRGLHSLILAFHELGKPIMGECNGGLAIAQTLDPITGKSILAGRAVTTHSWLDEY------------------------------------------------------------------------ +---MKIAVVLSGC-GVFD------GSEINEVVLSLFELEKQSINYEVFAQDKNQK---HVINH--YNQSS-D-NFTRNIFESSRIVNIKKLSELNYNTFDGLLIPGGFGVAKNLAIDIEFKKIMTNFI--GKPSGYLCIAPMLIPHVYR--------N--KCTIGNDP--E---------------MAKIINDLGGIHVNCS---ANDIVIDNRLITTPGYMM-------------------- +---MKIAVILAGS-GVFD------GSEIHEATLSLLALDQAGVEYQCIAPNIEQS---ANVNH--LNNEAL--SSARNVEESARIANVLDLAEAKSSDYDALLIPGGFGAALDFAVNKNLEDFILEFYQDRKAIGAMCIAPALIAKVLG--------KDVLVTIGNDE-GT----------------ADAIEACGAIHENCA---VDSIVVDNRVVTTPAYML-------------------- +--MKNVAVILSGS-GVFD------GAEIHEAVLVLYAIEKEGASWHCFAPNIEQL---HVINH--KTGEEM--SESRNVVESARIAKIEDVAKLNVDDFDALLLPGGFGAAKDFAINTHVASACRAFANAGKPAGYLCIAPVIIPMIYK--------DQVKGTIGADE-AT----------------GVAFSALGGEHIECA---VNDYVYDRKVLSTPAYML-------------------- +--MKKIAVVLSGS-GVYD------GSEIHEAVLSLLAIEKHGAQWHCFAPNINQH---HVINH--ITGEE-M-DTTRNVIESARIANISDITTLDVNQYDALLLPGGFGAAKDFAINESVATACRAFAEVKKPAGYICIAPVIIPMIYS--------KGVQGTIGDNK-EA----------------SDAFNALGGQHISSS---IEDVVFDHRVLSTSAYMA-------------------- +--MNKIAVVLSGC-GVFD------GAEINEAVLTLLALEERGILYDCFAPDISQH---HVVDH--ANGNEVS-SQQRNVSESARIVNIKPTSELNVSEYAGLLVPGGFGVAKTFAIESSFLKVMTNFAHAKKPSGYMCIAPVLLPKVY---------HNIRCTIGHDA-DT----------------AAIIEELGGSHIKCD---VDDIVIDHNVVTTPAYML-------------------- +--MKQVAIIFSGC-GVFD------GAEIHESVLTMLHLEQQNITYRCFAPNIEQH---HVINH--VTGEE-Q-AETRNVTEAARIADISDLAQLNVDEFAALVIPGGFGVAKDFAILDSLKSVCQQFSQKSKPITYLCIAPALIGHIHQ--------AGTKATIGNDS-DT----------------AAAVNALGATHVDCA---VTDIVVDQKVISTPAYML-------------------- +--MKKIGVVLSGC-GVYD------GTEIHEAVITLLAIARSGAQAVCFAPDKSQS---DVINH--LAAEP-M-AENRNVIEAARIAEIQPLSQARAADLDALIVPGGFGAAKNFAVDSSLAQLARSLHQAGKPLGFMCIAPALLPKIFD--------FPLRLTIGTDIDT-----------------AEMLEDMGAEHVPCP---VDDIVVDNKVITTPAYML-------------------- +---MKVAVLLAGC-GVYD------GSEIYETTITLLALDRAGVTYQCIAPDIEQA---HVINH--LTGEVDE-GETRNVKEAARLAEVIELGQAKAEDYDALIVPGGFGVAKDFAIHPPVKDFIQAVHKAGKPVGLICISPTMTGLLFG--------D-ATCTIGSNT-EV----------------AAAIEQMGGRHQPCP---VDDFVVDNRLVTTPAYME-------------------- +--MKKIGVVLSGC-GVYD------GSEVHETVLTLLAIARNGAQAVCFAPDKSQS---DVINH--LSRES-L-PETRNVIEAARLTNIAPLAAARSADLDALIVPGGFGAAKNFAVDADLKALTLAMHREGKPVGFMCIAPAMLPKIFD--------FPLRITIGTDIDT-----------------AEVLEEMGAEHVPCP---VDDIVVDNKVVTTPAYML-------------------- +--MKKIAVLLSGC-GVYD------GTELHESVLALLEITKSGASYQCFAPNIPQY---HVVSH--LTGEVQE-NETRNVVESARIADIKAVDELNIAEFDALVIPGGFGAAKDFAVEPSVERFISQFASAHKPVGFICISPIMIPKLYG--------HGVSGTIGSDE-AT----------------AAAFEQQGGQHHAVS---VHDIVVDHKVVSTPAYML-------------------- +-MGKRIGVVLSGC-GVYD------GAEIHEATLTLYFLDKAGTKVVCMAPDKDQF---HVVNH--LTGDE-M-PERRNVVESARIADVKRLDEVKATELDGLIIPGGFGMAKTLAVDEDLVALVMAMHGAGKPIGALCITPAVLSKILA--------E-VRLTIGNDE-GT----------------AEAIRNMGNTHVESG---AEQIIIDNNVISSAAYMC-------------------- +-MSKKFAVILSGC-GYLD------GAEIREAVLTLLALDSANANYDIFAPNENQF---HTINH--MEMSEEK--EQRNILESARIAKVIDLNQLNTNDYAGLLIPGGFGVAKTFAATAKVTEVITNFNDQQKPIGAICIAPALISLVLG--------HGIEVTIGTD--ES---------------TASEIEKTGAKHINCE---RNEFHLDNKIATTPAYMF-------------------- +--MKKIAVILAGC-GHQD------GSEIRESVLTLLELDKYNVKVAIFAPNVKQY---DVINH--LDGSVMN--ESRNLVEAARIAEISALDKLKSKDFDALIIPGGYGVAKDIAAIPEVKNIINDFIREKKPIGAICIAPVVVAQAVK--------GKVKLTLGEEN--------------------NLLTAFSAEQEVCP---TESCVYDNKIVSTPAYMR-------------------- +MNSKKIAVLLAGC-GVMD------GSEIHEAVTAMLAIQQQGADYDCFAPEGDQG---VTINH--LTKQPEP--QKRRMVEAARIAEINTLKNFKAENYDALLIPGGMGAVMDFAVHPDVERAVIEMHQAHKPIVALCIAPVLVARILK--------D-VTLTIGNDP--E---------------TAMALKNMGANHQVCS---AAEVCIDNKIISTPCYML-------------------- +---MKVGVLLAGC-GVFD------GAEIHEATLTLYFLDKAGAEVVCMAPNIPQK---EVINH--LTGEKTE--ETRNVVEAARIANIKDINEVSADDIDALIMPGGYGVAKNFLVIPEVKRLLIEMFEKKKPIGAVCISPVIVASALR--------EKAKLTIGSDE-EV----------------AKAIEAMGQQHLVCP---VSEALVDNKIVSTPAYME-------------------- +---MKIGVLLAGC-GVFD------GAEIHEATLTLYFLDKAGVETLIMAPNIKQK---DVINH--LTGEPMN--EERNVVEAARIANIVDIDQVKAEDIDGLIMPGGYGVAKNFLVIPQVKRLLVELFKAGKPIGAICISPVIVAAALR--------EKPTVTIGTDV-DV----------------AKTIEAMGARHLSCP---VNEMVVDNKIVTTPAYML-------------------- +MQQQKIAVILSGC-GALD------GSEIHESVLTLLALDRAGLPYQCLAPSIPQT---RVVNM--ETGKTKE-HIERNVEESARIAKIKPIDCANPEEYTGLIVPGGFGVALNFGIQRDVFHFAKSIADAKKPAGFICIAPILAPKLYP--------AGIKITLGNDN-PT----------------AKIVEKLGAQHIPCA---ATACVVDYRIVTTPAYML-------------------- +MSKKSIAVILSGC-GNRD------GSEIHEATLTLWAIHKNGADYQCYAPNITQH---HVLNH--ITGQEM--TEQRNVIESARIAAVRDLSDFDAAAHDAIIIPGGLGAAKSYAINTDVKKAIIAMFEDKKPIGALCIAPVILAKLLN--------QVR-VTVGQDP-AT----------------ARNIETMGAHHTTTL---HGEIVVDHKVVSTPCYML-------------------- +--MKKVAVILSGC-GYLD------GSEIRESVLTLLALDTANIEYQIFAPDEPLF---HVIDH--ASGEINM-TERRNIQEAARIAEISLLHKLDANEFDGLLLPGGFGVAKTFAVHGTVASILKAFHQSKKPIGAICISPALLALTFG--------EHPTITLGSDL--N---------------IAKEIEKTGSIHRVCQ---TSDCVVDNLFVTTPAYMD-------------------- +--MPKIGVIFSGC-GVFD------GTEITEAVMTLYFLEKKGADIVCMAPNIEQY---HVVNH--LTGDVDE-SKKRNVEEAARLVNVKDISEVDINELDALVIPGGFGAAKTYAVNEDVKKAVNTIVTSKKPMAAICIAPVLVAKALE--------GTSKITIGSDE--N---------------VAGSIESFGATHVECP---VKEAVVDNKIITTPAFML-------------------- +MSTKKVCVILAGC-GVFD------GAEIYESVFTLLALEKAGAIVTCVAPDVAQM---HVINH--ATGEVAA-GETRNVVESARVANITPIADVKGSDFDAIIMPGGFGVAKTFAIHPEVERVLKEAYSAKKVLGAICIAPAVVARVFG--------DNVKLTIGSDS-AT----------------AEQISRTGANHIEAR---VTDVVVDHRIVTTPAYML-------------------- +---MNCAVLLCGC-GHMD------GSEIREAVLALLALDSYGINVTCCAPNIKQV---DVVDH--LSGSTLE--EERDISESARIANVVDPKDISPNDFDMLILPGGFGVAKDLLVLEEIKKTIVKFNKEKKAIGAICIAPAIVAASLS--------SKVKVTLGEDV-------------------DSIISRCGGEHVFCE---TDDYVADMGVFSTPAYMR-------------------- +SNMKPIAVILSGC-GVLD------GSEIHESVLTILSLSQNNVEMCFFAPDREQL---DVINH--ISEKE-K-QEKRNIVESARISKIAPLASADANKFSAVIIPGGFGVAKNFVIDKDLLTFCRKIHQQGKPMGLMCIAPVMLPKILN--------K-VTLTIGNDK-ET----------------IAQIEQMGGKHIICS---FDDIVVDNRVITTPAYML-------------------- +-MKKKVGVILAGC-GYLD------GAEIRESVFTLLALDKNDAEAIIMAPNIEQH---HTVNH--LTGEEVN--HNRNVEESARIAKIQDITKVNIDELDALVLPGGFGVAKSLAMNPEVQKVIEKVHKANKPIGAICISPAVLCLALG--------KAPEVTIGNDV-GT----------------AQAIEVMGAKHINCE---VDEIHIDLKIVTTPAYMF-------------------- +MPTKRFAVILAGA-GKLD------GNDLHEAVLLLAAVARHGATYQCFAPDVEQH---EVVDH--LTGNPMP--ERRSVRESARIADVKPLSAFRANDFDGLLMPGGYGVAKTYAVNAEVAAAIKEMHAQGKPIGAMCIAPIVLAKVLG--------H-GTITLGQPS--E---------------TSHDAEKMGMTLQSSG---HGQVVVDNHLYTTPCYML-------------------- +MNEKRIAVILSGC-GVYD------GAEINEVILTLLSLEENHMKYECFAPNMEQH---HVINH--LTGKE-M-SEKRNIVESARIVKIKDLMKCDSSHFSALIVPGGFGVAKDFALQKPFFDICKKFKDEEKPVGFMCIAPVLLSKIYG--------EGINLTVGNDQ-KT----------------IEIISSTGGIHKEST---VDNIVVDNKIVTTPAYML-------------------- +SSKPSIAVILAGC-GNKD------GAEIHEATLTLWAIHRHGADYQCYAPDKKQH---HVLNH--ITGEEM--AEERNVIESARIANIKSLAQFDATAHDVLILPGGFGAAKSYAVDESVAAAVRAMHAAKKPIGALCIAPVILARLLP--------NVM-VTVGSDL-QT----------------ADNITRMGARHQKTT---HGEIAVDNRVVTTPCYML-------------------- +--MKKIAVILSGC-GVFD------GSEIHEVVLSLLAIEQNGAEWVCFAPNIYQH---HALEH--STGTE-H-IDSRHVEESSRLSEISDVVTLDANDFDALIVPGGFGAAKNFAINSHVLKACKSFKKATKPTGFMCISPVMLPAIYG--------KGVKCTIGNDT-KV----------------ADFIESQGGKHVNCM---TQDIIWDNKVGTTPAYMT-------------------- +--------------------------------MSLLALDRAAVSYQCFAPDVRQA---HVVNH--LTGEEMG--ESRNVVEAARIANLKPLSEAKVDEFDLVLLPGGFGAAKNFAALPELVEFLKAAHAAGLPIGFACIAPAIAARVFG--------EGLSFTIGDDA--G---------------TASALSKWGARHEARS---VTEVVVDLKIVTTPAYMF-------------------- +ATSKKVAVVLSGC-GFQD------GSEINESVLTLLALDLNDAEYHCFAPDIIQT---KVQDH--YKQQEM--DEQRNVVESARIAEIKPLTEFQASEFDAIILPGGFGAALDFAINADVEQAIRSMHSLHKVIGALCIAPVLLAKLLP--------NAE-LTIGQDE-GV----------------ANAVVTMGATHHKTN---HAEIVIDNNLVTTPCYML-------------------- +GCMSKVAVILSGS-GVFD------GSELHETVITMLHLEKLGVKYQTFAPDTQQL---HTIDH--STGEAS---EGRNVVESNRVSTTQPLTELNHRDFDALIFVGGFGAAKDFAVIPSIGSVITEFNQNNKWILAMCIAPVLLAKVVS--------G--KLTIGSDS--G---------------TIEAMATTGVNHVTCS---VVESCVDNKLITTPAYML-------------------- +KKMPRFAVVLSGC-GRAD------GSEIHEAVTALLAIDCAGCAYRCFAPDIEQA---AVINN--LTSEKME--ERRNVVESARIADIKPLNKLNVGDFDCIVFPGGLGAVTDFAVESSVSRVLEDAYKNKLVIGAMCIAPVTVSKVLG--------KGITVTIGNDK--T---------------VAKTIELTGARHQDTP---VTEACIDHRVVTTPAYML-------------------- +-MTKQVAVILAGC-GVYD------GSEIYETTLTLLRLDQLGIDYRCFAPDIEQH---HVVNH--LTQEVVE-GEQRNVLESARLADISPLNELVADDFDAVIVPGGFGIAKDFAVLEALKEALIGFRQENKPIGLMCIAPVIVPRLFD--------DGIAVTVGNDP-AV----------------SGAISAMGGLHRSCG---VEDIVVDHRVVTTPAYML-------------------- +FMVLNSAIILAGC-GHMD------GSEIREAVLVMLELDRHNVKFKCFAPNNDQK---HVMDH--YNKKTTG--EIRNIVESARIASIYDIEEINHEEFDMLVIPGGYGVAKNLFILPKFKNAVLKFFNSNKPIGAVCISPAVLVASLK--------DKIKVTIGEDS-------------------DNLIDKLGGIHIDCP---TIKSVRDNKIFSCSAYMR-------------------- +QLSPRIGVLLAGC-GYLD------GSEIHEAVLTLLAISKKGAQAICLAPDMVQH---HVVNH--LTGQEVI-GESRNVVEAARIAAIHNLSDIASLHLDAFIVPGGYGAAKSFAIHPDVATAIQLFYKAGKPMGFICISPVLAAKVLG--------SKIEVTIGNDA-ST----------------AASIEAMGARHINCV---VTKAHVSHNIVSTPAYML-------------------- +ASQKRVGVVLSGC-GFLD------GAEIHEAVCTLLSLDRRGVKLVATAPDVEQL---HVVDH--VKGAPAD-GERRRVVEAARIVQITPLSAVSGRDLDALVFPGGFGAAKSFAVLPEVERIVREVRGAGRPMGFICIAPVIAARLLG--------PGVKVTIGNDR-DT----------------AAAIESWGARHVDCK---VEDAVVDLKIASTPAYML-------------------- +---MKTAVLLSGC-GVYD------GAEIHESVCALLALSQNNLDFICTAPDLDQH---HVINH--VNGEEIN--AKRNVIESARIADIVSLVDLDENNISSLVIPGGFGAAKEWAVLKEVKDLILHCIENKKPIVSLCISPTLIAK-----------SIPQLTLGSTQ-SISEYD--------IAEIHEAISSVGAVTNNRC---IDEVCVDLKIISAPCYML-------------------- +--MKKIGVLLHGN-GVFD------GSEIHEAVFTLLAIAEAGAEAICFAPNVLQH---HVLDH--LTGLEMP--ETRNVVESARITTIKDIIDIKVSELDGLVMPGGFGTAKKWAVLESVKTLIVELVRQGKPIVGLCMSPTTIAKALE--------GQAHLSVGTTK-EASPYD--------IAAISAGIESIGHVAEMTS---VREIMVDLKIITAPCYMM-------------------- +TDKPRFAVLLSGC-GVFD------GAEIHESVLTLLAIDRQGGVARCFAPDRPQY---HVIDH--RSGQP-T-GETRNVCESARIAAIDDLADFDPAAFDALILPGGFGAAKSFAVDPTVERALRAARAAGLAIGALCIAPVVLARVFG--------EGV-LTIGSDA-AT----------------AEAITALGAHHQKAT---HAEVVVDLRLVSSPCYML-------------------- +RKIRNLCCCPCWL-RSFR------RAEIHEATLTLLYLAQAGVDYECLAPNRDQY---HVLNH--LNQEK-M-HEKRNIIEGARIANIKAIDQANIGDYDAIIFPGGFGAAKDFAIQEDVLSFAQQAYHATLPLGFICIAPIMISAICG--------P-IQHTLGKDQ--E---------------MINIVHQLGGKHINCQ---ADEIAIDHKIVSTPAYML-------------------- +--MKKIAVVLAGC-GHLD------GAEIHEATLTLLYLAQAGVDYECLAPNRDQY---HVLNH--LNQEE-M-HEKRNIIEAARIANIKAIDHANINDYDAVIFPGGFGAAKDFAIQDDVLSFTQQAYHAALPLGFICIAPIMISAICG--------PNIQHTLGEDE-EM----------------INIVHQLGGKHINCQ---ADEIAIDHKIVSTPAYML-------------------- +-MMKKIAVVLAGC-GHLD------GAEIHEATLTLLYLAQAGVDYECLAPNRDQY---HVLNH--LNQEK-M-HEKRNIIEGARIANIKAIDQANIGDYDAIIFPGGFGAAKDFAIQEDVLSFAQQAYHATLPLGFICIAPIMISAICG--------PNIQHTLGKDQ-EM----------------INIVHQLGGKHINCQ---ADEIAIDHKIVSTPAYML-------------------- +NEAPKFAIVLSGC-GVFD------GSEIHEAVCTMLAVDQSGCTYQCFAPNTWQA---RTIDH--FTGHADE--DNRNVAESARIAEIKDLAEFKAKDYDAVIFPGGFGAALDFAVNVEVRRAIEESYREGIVIGAMCIAPTVIARVLG--------KGITITVGNDK--K---------------VAAGLAKMGARHQDCA---ATEVCVDHKIVTTPCYML-------------------- +--MKKVAVILSGC-GKLD------GSEVHEATLTLLNIDACGAKYQCASIDTPQS---RVMDH--LSSKESH--EKRNMIESARIAEIVDAGGISPKDYDAVIFPGGFGAALDFGVNPVIEKIIRDFHAAKKPIGAICIAPVIVARVLA--------SKAKITIGNDA--G---------------TAAAINKWGAEHVNCS---AEEICFDNLLVTTPAYML-------------------- +---MNFGILLSGC-GVYD------GAEIQEAVLSMLAVSELGDSYTCIGVNADQF---HVINH--LTGEPMN--ESRNMVEAARIANIVPIQDIQPRDIDALIIPGGFGSAKKWAILPEVKLLIVNLVNIGKPIAALCVSPVVVAK-----------AHPSLTLGTTT-ESSPYD--------IEAFSQGLQKTGAETTYKT---IHEIHVDNKIITAPCYMM-------------------- +HAGRRVAVFLSGC-GVYD------GAEIHEASAALVSITRAGAKPTIFAPNKAQM---HVIDH--TTGNEMK--EERNVLESARIADVKPMAEFAADQFDALIVPGGFGAAKDFAVDSEVEAAVRSFHDTKKPMGFCCIAPVIPAKLF----------KGKVTVGLE--EGDDWP--------YAGTAEAIRTMGATHEPHD---LSSVCVDNNIVTSAAFMC-------------------- +SSHRRVAVVLSGC-GVFD------GSEIHEATSMLIHLSKAKAKVDFFAPDMDQD---HVTNH--ATHKQVP--EKRNCVESARISNVSALSKLNPSNYDALFFPGGFGAATNFAVIPDVEKAIKGFHDLKKPMGFCCIAPVLAARCI----------GARVTIGTD--PG---------------TASAIEKMGAQHEDCQ---ITEVCVDNFVVTAPAYMC-------------------- +NNMKNIAVILAGC-GVFD------GSEINEVVLTLLHIEKNNAKYQCFAPDITQY---HTLNH--ITGEE-M-TESRNVVESARITNIKSLAELDITQFDALIIPGGFGVAKDFAVNDEVLSACKAFAKANKATGYMCIAPALLPFIYN--------KP-QLTIGNDS-DT----------------ADALTTLGAEHIECK---VDDIVIDNKLVTTPAYML-------------------- +KKFKNAAVVLSGC-GVFD------GSEINEVVFTLLELERNLINYSVFAPDIYQY---DVINH--ITGEK-M-KEKRNVIESGRITKVKSFSELNPNEFDALVVPGGFGVAKTFAINDEFANIMRAFNELSKPAAYMCIAPALLPKIF---------AGIKLTIGNDQ-FT----------------ADAIKTCGGEHITCS---VDGIVKDYKIITTPAYML-------------------- +MAKPKVAVVLSGC-GVYD------GSEIHEAVLTMYFLDKYGAELVMAAPDIPQY---HVVNH--LTGEEAK-GETRNVVESARIANIKNLKDLNVSEVDAVVFPGGFGAAKTFAIDPEVARVVQETVKAKKPLAAVCISPVLLAKALS--------GDPKLTIGTDT-GV----------------ASAIEKLGGKHISCP---VKEAVVDNKIITTPAYML-------------------- +MAKPKVAVVLSGC-GVYD------GAEIHEAVLTLLAIVRKGGTYQCFAPNIPQN---HVINH--LTGQEEH-GGSRNVIEAARIADIKDLREFRAADYDAIVFPGGFGAAKTFAVNTDVERAIKEVHAAGKPIGALCIAPALIARVLG--------NIT-VTIGNDR-DA----------------ADGIESMGSTHTLTT---HGQVVIDARVATTPCYML-------------------- +MDTKKVAVILSGC-GVYD------GADVHEVVLTLLALESGQASYQCFAPDIAHH---HVINH--ITGEI-S-HQERNVFESARIVEVKAITECHSRDFDAVIVLGGAGVAIDFAINSPTLEVLNSFKDENKPAGYLSIAPVLLPLIYG--------EGVELTIGNDA-DT----------------VAILESMGAVHRGAS---FDETVVDNNLVTSPAYMV-------------------- +PKQAKVAVILSGC-GVFD------GAEIHESVLTLLALARAGAKVICAAPDIAQR---HVINH--ATGEEVE-DEDRNVEEAARISKIEHVGQIKLDQVDAIIFVGGFGVAKSLAIDPIINSLIQDAHQQSKALGFICIAPVLAAAALG--------S-VRLTIGNDA-ET----------------AAILEHKGAQHVNCA---VDEIVVDNRVVTTPAYML-------------------- +MLGTNVAVLLSGC-GHLD------GSDPLEVSLLCLALSRLDIKPIFYAPYMSMS---TGVNH--VNGA--A-ETGRNVIESARLVSVLKLDELDPSDLSALIIPGGHGPLNDFKVIKEILGIIEGFKAAGKPIGCTSHANILVALAIP--------N-IEITLGSRDEEECPV---------ASLVAPGLIEQGTTVTPTS---V---QVDNKIVTAAASLF-------------------- +-MAQKVAVILSGC-GHLD------GSDAAEVSPICVALSRAGMTPVFYAPYVTMT---MGVNH--VNGV--C-DTDRNVIESARLVPVQNLQDLSAEDIIALIMPGGSGVLNNFAVQEDVVRVISEFKSANKPIGCTSYANVLISLVIP--------E-IEITLGGDDEEDYPN---------TPLLIDNLTARGTTITSTE---F---CVDNKIASIASFLY-------------------- +IMQKKVAVILSGC-GVYD------GAEIHESVLTLLRLDQRGAQVQCFAPNIAQH---HVVNH--LTGEDM--PETRNVVESARIAEVKDLREADVNDFDALIVPGGFGSAKDFAVNAELLALAEAFALAGKPVGLICITPALAAKIYG--------PGVICTIGNDPET-----------------AAAITKMGGAHQDCD---VSEIVEDRKLVSTPAYMV-------------------- +---MKIGVLLSGA-GVYD------GAEIQESVLILLALEQAGVSYFCIAPNIEQH---HVINH--LTGNEMN--EKRNVVEAARIANIKDLAEINADDMDGLVMPGGFGVAKKWAINPDVKKIINEMVRNHKPIAAVCMSPTTVAKALE--------GEANLTIGTTK-EKSPYQ--------IADINAEMKKVDANPVLCP---VTEVITDNNIVSSPCYMM-------------------- +---MKVGVLLSGC-GVYD------GSEIHEATLSLLALDHLGVEVQCIAPDIEQH---HVINH--LTGAEIP--EKRNVIESARIAKIQALNTVNSDDLDALLLAGGFGAAKTWAILPDVKHLILTMVHAKKPIAALCIAPTVLAKALQ--------GHPQLTVGTTT-APSPYD--------ITAINAGLNSIGAQTIMTT---VDGIVIDNKIITSPCYMM-------------------- +ENTLPVALVLSGC-GVYD------GSEVSEAVGVIVALSQAGIPYTCYAPDRPQL---HVINH--AKASETD--ETRNIDEAARIANILPLAELDVSRHSAIVFPGGFGAAKNFALADDVRAAVLPFIQAHKPVVALCAAPLVLGLAAR--------EGARITFGNPSEGKA--------------MAEALVSWGQQHVETA---VDAACVDHRFITAPAYMY-------------------- +MSKKNVAVILSGC-GVYD------GSEIHEAVFVMESISRNNANYQCFAPNMEQM---HVVNH--LTGEPS--SEKRNVVESARIANVQDLNNLDVSKYDAIILPGGFGAAKNFGVKEGVSSAVKAFHSAKKPIGACCIAPVILARTLP--------GVK-VTLGQEQ-VSEEYP--------YADACKAATVMGATHVPCG---ATDICVDNRVVTTPAYMR-------------------- +MGKVKVGVLLSGC-GVYD------GAEIHEAVITLLALDRAGAEIVAMAPNVDQL---HVINH--LTGDVVP-GEKRNVVEAARIANIRDLATVDPAELDALILPGGFGAAKDFAVHPEVARVVQGVHQQGKPIGAICIAPALIAKLLG--------Q-PKLTIGTDK-DT----------------AAALEKMGACHEACG---VEGVVVDAKIVTTPAYML-------------------- +STMKKYAVLLAGS-GVYD------GSEIHEATFALLSIKQNGADYQCFAPNKNQH---HVINH--LTGEEMP--ESRNIIESARIAQVKDLKELDASHYDGLVMPGGFGAAKKWAVDPDVKKTILDFLALGKPICALCVAPAILAKALQ--------DQAEVTLGSTA-EPSPYD--------IAGTHTAVSTLGVKTIEKT---LRDIHIDNRIITAPCYMM-------------------- +--MKKVAVLLSGS-GVFD------GTELHESVLTLLEIARAGACYQCFAPDIPQL---HVVNH--LTGEADE-TDSRNVVESARVADIKPVTDVVISEFDALIIPGGFGAAKNFAIDPSVKQFISQFTQASKPVGFICISPVMIPQCYE--------AGVKGTIGSDC-DT----------------AAAFELQGGSHQVTA---VDDIVVDNKVVSTPAYML-------------------- +--MAKVGVLLSGC-GVQD------GSEIHEAVLTMLHLDKNGQEIIPIAPNILQS---QVIDH--LTGDEME-RENRDVVEAARIADIRTIKAEVTDQLDGLILPGGAGAVKNYAINQQTEQLIIEMIETNRPVGAICIAPLVVARALA--------DQPKVTVGAAS--E---------------PAKYIEDLDAVHVEAA---VDEVVVDLKILTTPAYML-------------------- +EKKLKAAVVLSGC-GHLD------GAEVREAVLSLLVLDQQEVNVKCFAPDINIT---QVMNH--KTKEATK--EKRNVVEAARIAEIYDLKEAKAENFDMLVVPGGYGVAKDLAVMPEFERLVSEFFVTKKPIGAICISPAIIVSILN--------SKVKVTIGDDR-------------------EQLIEKLGGEHIKCD---TGLSIEDHNVFSCSAYMR-------------------- +---MKYLVLLAGC-GLGD------GSCIEEVILTYVALDKYGCDYTPVAE-DVSI---QSVNH--LTEEM---AEKRNIIEAARIGRIKDIHEVDFAEYDALIIPGGIGLLNDSN---VIKTCVTHFISEKKPVAAMCAGIDFLRRFYG--------RARE-----------------------------MK-------ELT---A---CFDNNVYYTPAFR--------------------- +---MNCLVLLSGC-GVKD------GSCPEEVALTYTALEKYGCAYQPVAD-DIPV---LTVDH--LTGQP---DQERQIKESARLGMLRKIRDVCWEDYDALVIPGGLGLLTHSQ---AVADCVRYFAAASKPIAAMCAGIDFLRGLLG--------GLEE-----------------------------VP-------PLK---A---CCDKKIFYTPAFK--------------------- +---MKFLVLLAGC-GLGD------GSCIEEVVLTYTALDKYGCDYTPAAA-DMLV---PSMDH--ITEQP---GEKRSVTESARTGRIRNLHDISPDDYDALLIPGGIGLVVESG---LVADWVNRFVQQKKPIGTMCAGIDFLRGILG--------AREE-----------------------------VR-------DLD---A---CRDGAIFYTPAFR--------------------- +--MATIGVLLSGC-GVLD------GSEIHEATLTLLYLHKAGAKVVCLAPEMTVE----AMDH--GAKKPM--GEKRNVVEAARIAPVVDAAEVGVADLDALILPGGFGAAKDFAVLPSVAALIKAMHAAKKPIGAICIAPAVLALALG--------EHPRLTIGNDA-GT----------------AQAVGAAGGVHVACP---VDGIVVDNRLVTTPAYML-------------------- +--MKKIAVVLSGC-GHRD------GSEITESVSLLIGLHQAGAEVHCFAPDI-QI---PITNH--INGEAQN--EKRSLTEAARIADIQSLDKLHAKDFDAVVFPGGYGAAKNWAVNPDVKRVILEFHSASKPIGALCIAPVLVAKVLG--------DKVTVTIGDD--AA---------------TAAEIQKTGAIHEECP---VNDYITDRKVVTTPAYMY-------------------- +--MAKVAVVLSGC-GYLD------GSEIHETVLTILALEKQGVEWQGVALNRDQK---QVINH--LHQSVDSKASPRNIEESARITNVIDIADADSDDYDAIIFPGGFGAAKDFAMDEEVLKFARAFYLADKPAGYICIAPLMIPLVYP--------E-TKATVGTDE--N---------------TTAILAKKGAEAIIMD---ATDICVDVKIVSTPAYMC-------------------- +--MAKIAVVLSGC-GYLD------GSEIQETVLTILALEKQGVEWQGVALNKNQK---HVINH--LHQSVDSKASPRNIEESARITNVIDIADADSDEYDAIIFPGGFGAAKDFAMNQDVLTFARAFYLADKPAGYICIAPLMIPLVYP--------E-TKATIGTDE--N---------------TSAILEKKGAEAILMD---ATDICVDVKVVSTPAYMC-------------------- +--MKKVAVILSGC-GYLD------GSEIRESVLTLLALDTAHIEYQIFAPDEPLF---HVIDH--VSGEINM-TERRNIQEAGRIAKISSLDQLNENEFDGLLLPGGFGVAKTFAVHSTVASILKAFHQSKKPIGAICISPALLALTFG--------DRPTITLGSDV--N---------------TAKEIEKTGSIPHVCQ---TSSCVVDNLFVTTPAYMD-------------------- +MDKKKIGVLLSGC-GVFD------GTEIHESVLTLLFIDQAGAEAVCFAPDIPQA---HVINH--LTQQEE--KETRNVVESARIAEIQNINDVDVAQLDAVILPGGFGAAKEFAVNKDVVALLEKVIEAKKPLGALCIAPATVGMALK--------DSPELTIGSEE-GI----------------IGALESIGVKHALCK---VDEIAVDNLIVTSPAYMI-------------------- +--MKNIGVILSGC-GVFD------GSEIHEAVLTLLYLSQENASVHFFAPDSRQL---HVVNH--NTQQVRE-GETRNIVESARIAEVTPLCNLDIDALDAIIFPGGFGAAKTFALLPDVERVLKEAHAKGKVIGAVCIAPVLVAQAFK--------KHPRLTIGSDA-EV----------------NRVLTNWQAEPVCAG---VDEIVVDNKIVTTPAYML-------------------- +-MSRKASFILSGC-GYLD------GTEINEAVLLSLLCAQHDIEVDFYSVNEDVP---VSCHS--LSGEV-G-TEARNMEESSRIAEVFQVHTLDVDKYDILVLPGGYGAINNFFVYPSIQDIIYGFITAKKPIVSVCIAPLVVAVSLQ--------GGLTLTLGKDENRL-------------------LASVGAINKVCM---A---VYDNLIYSTPAFM--------------------- +-MNRKVAFFLSGS-GHLD------GTEITEAVTLRVALAQHGFDVVCFAPNRSQT---DVINH--QEQEA---PELRNIVESSRIANIAPIDQFDASEYVAVIMPGGFGAVKNFILMSDIGRALNDAIAHHLWIVAICAAPLVAAIAMR--------DAATVSFGAAENAGN-------------FL-PALNDWNINHIDTK---L---HTDHKLITSGAYMF-------------------- +EKKKTAAVILSGC-GFMD------GSDVVESVSVIVELTRKGIVPRFFSPHEEID---ESYNY--ITKQI-S-SEERYMKESARIAKILSIDQLRADQFDMLVIPGGNGVVRNFEVNSHVEKAIVDFFKQKKPIGFMSNSVILGAKALG--------KGIAVALGKTLDRVFVE----------TLM----TKFGNELSQED---A---CTDHRIASVASVSA-------------------- +KIKKKAAIVLSGS-GMMD------GTEIHEASACAVHLSRLDIQPKFFSVPCPQT---DVIDH--YKLSPTN--EMRNAVESARIAKICSINSLTSDEADVLIFPGGFGVAKTFDVNEEVVRVVNEFCACRKPMAFTCIAAILPAR-----------IGVKVTLGKKG-DPKKWP--------HSEAIDTVSDMGAVVEVKN---VDSFTFDFLVFTTPAFMY-------------------- +--MKKFALVLSGC-GQHD------GSETHEVILTLLSMAQEGVSWEAFAPDIIQD---KVINH--LTDQVEA-SEKRSVKESARLVKIQSLSMANAADFDAIVFPGGLGAVSNWKIITEVKRFIDDAVKLKKPMGFICIAPIMIPSIYS--------N--SLTIGNDA--T---------------LANQIKEMGSNHINCP---ATEVVVDNKLVSTPANMV-------------------- +--MPNVAIILSGC-GVYD------GTEINEAVLTLLELERNGISYQTFAPDMLQA---HTINH--AKGEATQ--ETRNVVESNRITETSALEDLDASEFDALVFVGGFGAAKNFAAIPQVSEVIRSFHSQNKWIVALCIAPVLLASTLP--------N--KVTIGNDQ--E---------------IARLLESKGHTHVDCK---TDSFVVDNQLITTPAYMT-------------------- +NNPRRVAVVLCGC-GRGD------GSEIHESSAVIINLSRAGAEISMFAPNMEQY---HVIDH--HAGTVDE-GKARNMIEAARIAEIFPLNDLEPENFDAIIFPGGAGVGKNFAVLPEVEKIIRAFHRAKKPLGFVCITTVIAAK-----------IGCELTIGNDTPQSGRWP--------LASTTKILENLGVVHVNKD---VTEAHVDNKIVTTPAFMC-------------------- +VATKRVAVVLSGC-GHLD------GSEIREAVFVLTELSRANAKYQCFAPDIQQM---HVVDH--SDGSIDS-GSKRNVVEASRIGGTLPLTDLKANDYDALMFPGGFGAAKNFAVHPEVERAIKEFNQAGHPIGLVCIAPVLAAK-----------V--EVTMGS-DEVSEEYP--------NASAAQAVKEIGGKHFNTK---LNEAHVDKKVVTSAAYMN-------------------- +MSTGKIGVVLSGS-GVYD------GSEIHEASATLVALTRAGKTPVVYSLDKDQA---HVIDH--SKGIPIE-GQTRNVVESSRIAAPIDLKSLELGDVDALIFPGGFGAAKDFALDPVVESKIKDFHSNGKPLAFCCIAPILAAK-----------TGVSITLGKRG--AGWP---------HEGSLDAANSLGANVVEKE---VTEVCVDNKVVSSPAFMY-------------------- +LAAPRVALVLSGS-GVYD------GTEVHEASAAMGALSRQGADYKIFAPDKQQH---HVVNH--MTGEEMD--ESRNVVEAARIANIQALDKLQVADFDAVVVPGGFGAAKNFAVDATLTDILKKFHAEQKPMGFCCIAPVIAANLF----------KGEVTMGSDT-ESDKWP--------FAGAAGACKEMGADYVVGD---ESKVHVDNRIVTAPAFMA-------------------- +AMSKRVAVILSGC-GVYD------GTEIHEASAVLVHLSRAGAKVQMFAPNSDQM---HVVNH--CEGKPTE-E-KRNVQESARIADVADLAKLDVSAFDAVIIPGGFGVAKDWAIQPQLEKIIKAFHKAGKPLGMCCIASVLAAKVLP--------G-CELTVGADKECDIVRW-------PYAQTACAMKEMGCKHVNTE----EKAHVDNKLVTTSAFMC-------------------- +--------MLSGC-GVFD------GSEIHEAVIALLNLQKRGVSTEFFAPDTDQF---DVVNH--LDSIAM--QPRRNAVESARIAKIQPLAKFDAGNFDILLFVGGFGAAKTFAVNKHVESAIVAALAKKISIAFMCIAPVIAAKVIG--------GGVKLTIGNDP-ST----------------AAAIEAMGAKHIECQ---ANSFVEDKKVYSTPAYML-------------------- +LQANKVAVVLSGS-GVYD------GSEIHEASACLVHLSRHGAQVSIFAPDKPQL---HVSNH--VKGEVME-GETRNVVESARIAAISSLSELKADSFDAVVFPGGFGAAKSFAVDGEVERVIQDFKKSKKPMGFCCISPVLAAKIIP--------G-VQVTVGQDSEQDGKWP--------YSGTAGAIQVMGGQHINRE----NEIHIDENVVTTPAFMC-------------------- +AMVKRVAVILSGC-GVYD------GSEVHESSAVLVHLSRAGAKVRIRPPRHII----DC-RG----------GRNGLILGSGL--S-------VGSPHVLPVPSYGGFARLDMAVL---SRSARNLDFFH----------SYVASAVA--------NGVTAAVDP-PALLCSAPRW----PYAGTAA-AVKEMGCKHVNRD---V---HVDNKLVTTSAFMC-------------------- +AMAKKVAVILAGC-GVYD------GSEIHESSAVYVHLSRAGAQSVVYSRSIPLL---NSLRH--LYLSS-F-RCNTFLVQTAHSCCVHS--RVATHSHSHPHPPWRQGARR---LH---ERMSRNWDCTSK--------NVFVCGVLA--------QGVRVHVKARRYAQERGFKW----PYAGTAA-AIKELGCKHVNKQ---V---HVDNKLVTTSAFMC-------------------- +CTSTRVAVVLSGC-GVYD------GSEIHEAVSVLSHLTRNDAVPVVFAPDVKQM---HVINH--LKGEVDS-THSRMVPESARIANIQSICELNISCFDAVIFPGGFGVAKDYAVIPEVVKVIQEFHNAKKPQGFLCISPILAAR-----------VTVKITLGKNS--CDKWP--------HRGAIEDAKKMGATVELRN---WDEVSFDNLIFSSPAYMY-------------------- +TDSNKVAVVLSGC-GVYD------GTEIHEAAAVLSHLTRNDAIPCCFAPDVPQL---HVINH--LKGEEDK-THQRNVQESARIASVENLCKLNQSCYDAVIFPGGFGAAKDFAVHPDVVKLLKDFHCAKKPIGLICISPILAAK-----------VNVRITLGRDS--CDKWP--------HRGAIDAARKLGAQIEERD---VNDYVFDNMVFSTPAFMY-------------------- +--------VLSGC-GVFD------GSEIHEASAALVSLSREGVKYSIFAPNIPQM---HTINH--LNGQEES-VNRQVQYKSARIANIAALDTLVANDYDAIVFPGGFGAAKTVAVNDEVQRVIVDFHKLKKPMGFCCIAPTIVAK-----------VTGEVTVGQSKNDDGKWP--------YADTAQAIEKMGAKHPNFM---THEIHVDNRVVTTAAFMC-------------------- +AAPRKIAVVLAGN-GVYD------GSEITESVATLVHVSAAGFAPACFAPDIVQH---HVVDH--TKGEEDS--APRNVVESARIAQIAPLTSLDPTEYAALIVPGGFGAAKNHAVEPSLETAIRAFHAAKKPIGLCCIAPVIAAH-----------L--EVTVG--QAEGEQWP--------YGGTAGAIENYGGVHRPTD---WSGVCVDNNVVSSAAYMY-------------------- +PPSRRVALVLSGA-GVYD------GSEIQEAVSCLIHLSKANADVRVFAPDILQH---HVINH--LTGDVMP-AESRNVVESARIAKVEKLDLLDVAQFDAVVVPGGFGAAKSFAVQPQVAAALTAFHAAKKPIGLICIAPVLGGKLF----------GAELTMGRR--SGAKWS-------SGPDAASAVESWGAKIIEKD---HDEVHVDNKIVSAPAYMY-------------------- +RPAARVALVLSGC-GVYD------GTEIHEASAILVHLSRGGAEVQIFAPDVPQM---HVIDH--TKGQPSE-GESRNVTESARIAKITDLANLSAAHHDAAIFPGGFGAAKTFAVNKEVERVLKEFHQAGKPIGLCCIAPVLTAKVLR--------G-VEVTVGHEQEEGGKWP--------YAGTAEAIKALGAKHCVKE----VEAHVDNKVVTTPAFMC-------------------- +WGNTNVAVVFSGC-GWWD------GTDVHEATYTMYHLSRNGARFQIFAPNQQQM---HVMDH--SKVQP-S-GETRNMVESARFSQLHDLSRLDVNNFDAVIFPGGHGVAKTFNLHNDVERILKDFHRSRKPIGLSSMSPLLACRVLP--------S-LEVTMGYERDENSRWGRW----PNTSMVQ-AVKNMGARHNVRE---AHEACVDNKVVSTPTFMW-------------------- +WGNTKVAVVFSGC-GWWD------GSDVHEGVYTMYHLSRNGARFRTFAPNQQQM---QVMDH--MKKQP-S-GENRNMIESARFIQMQDLSTLDVNSFDAVIFPGGHGIVKTFMLHNDVERVLKEFHRSRKPIGLASMAPVLACRVLP--------S-IEVTMGYERDESTRWGNW----PQTNMVQ-AVKGMGARHVVRE---P---YVDNKVVSTPSFMW-------------------- +CDNPQVAVVLAGC-GVYD------GTEIHEAAAVLSHITRNNATPFIFAPKIPQM---HTINH--ASGEEDK-GSKRCTAESARIAEIKPLSELNYKSFSAVIFPGGFGVAKDFAVHPEVVAILQGCHRSKIAMGFACIAPILAAR-----------VNVTITLGNFS-PAESWP--------HREAIEAAKAMGAVLEFKG---VNEISIDNNIYSTPAYMY-------------------- +---MPVAVILCGC-GYLD------GTEISEAMSAMIHICLKDMKPHFYAPDVNIC---ETVDH--FIKKP-D-SPSRNAVEAARIADIKPLCQCQACKHEALVIPGGFGAAKNFAIHPDLEQIIEDFYYEGKPIASICISSVLVARVLK--------G-VKITLGKESPAEEWPF--------ADAIK-KAKDMGAKIEQKS---V---TKCYNVFSTPAWMY-------------------- +CDPIPVIVVLCGC-GGLD------GTEISESISLAINLSHHNFYPKFFAPDMEIC---GVVDH--LTKEP-C-GEPRNAVEAARLASIKSLSDCQSQCGAALIIPGGFGAARDFALIPDLRRVIEEFNCEKKPIGTMCIASALVPRVLQ--------G-VKVTLGKDGCKDDWPY--------AEAIR-RVKDMGAKVEEQD---V---TYCYNVYSTPAWMY-------------------- +--MQVMGVFLCSS-DFSN------GTEFSDAFLTVCSVKKHTAKALFIVADDSER---AVIKD--LIEKC-A-NEKK----SSYFDEIISLKESVPELLSSLIFSGGFGVINSFEIDEQLFTLVSEIHKQRKPIGFVSQSSLLAPKLFD--------TSIRVTLGNDADRA---------------E--LLDAIGAEPVFCP---A---VVNMRIVSTPGCLS-------------------- +---MKCGVVLTGC-GSED------GTAVDEAIMTFLALDKAGVEVVSLALDKDQY---EVINH--QTGKP-L-EQKRNQVESARLLPVNNIDTFNWEDLDLLVIPGGKGVLKTFEVNKSLERLIVNCFFGKKPLGAIGEGVLILARALE--------NNLTV--TASGNPED-------------RM-TVVEKLAIDHVPCE---V---CVDNKVVTAPLLV--------------------- +---MKAGILLSGC-GLGD------GTQIEEVMLTYLSLDKYGIDYITFAPNEMQH---DVIDH--YTEKP---NEKRNIIESARIGKICDIREVSCKDIDAIIIPGGLGVFKTFIVNKNVDDLLKAMYLSKKSIAGICGAVILIAKSLS--------QDLKV--ATANDAY---------------G-ELLS-------ELN---V---NCSECV---IDRK--------------------- +---------------------------------------------------------------------------------------------------------------------------------EGKVIASICHGAQLLISA-------KTVKGRKVSGYYSIKD-------------------DITNAGAEYVD------APFVVDGNLVSCPHYKYLEHWMKETL----------- +---------------------------------------------------------------------------------------------------------------------------------AKKPIGQICHAGWVLVSA-------GILEGVNVTSTPGIKD-------------------DMTNAGAIWHN------EPVVTDGHIISSRRPPDLPEYLPAFI----------- +------------------------GSEEMEALNLIDILRRAGANVTVASVEDKLQV-----VT--------RR-----HKF--NLIADIMVEEAAKREFDLIVMPGGLPGAQKLSSTKVLVDLLKKQAESNKPYGAICASPAYVLEP------HGLLKGKKATSFPPMAHLL-------------------TDQS---A-----CDSRVVVDGNLITSKAPGSATEFALAIVEKL-------- +-----------------------EGFQLLDVFGPLDMFGNEGVRIVMLGE-RGAVASSA--------GP--------------TVAVECALDSAP--PVDILMVPGGMGT-RREVDNAALVAGIARLAHTAPHVTSICTGAALLARA-------GLLYGRRATTNKRAFA-------------------WVTSQGPKAVK-----RARWVEDGHLFTSSGVSAGTDMALAL------------ +-----------------------DGFQLLDVFGPLDMFGNEGVRIVILGE-RGMVASSA--------GP--------------AVAVDHALDAAP--HIDILMVPGGMGT-RREVGNTAFIASITRLARSAPHVASICTGAALLART-------GLLDGRRATTNKRAFN-------------------WVMTQGPKVVK-----QARWVEDGHVFTSSGVSAGTDMALAL------------ +-----------------------DDYETLDLHGPVEMLGHA-VEIELIGP-GAVARSFQ--------GP--------------KVVVDRPLAQLE--PLDLFLVPGGLGT-RALVQQPELIELIRRQALMSERVLSVCTGAALLAQA-------GLLDGKRVTTNKAAFA-------------------WVASLAPDAQG-----RARWVQDGNLTTSSGVSAGTDAALAL------------ +-----------------------DDYETLDLHGPVEMLGHP-AEIKLVAT-KEIVKSYQ--------GP--------------RMVADCLTNQTY--DCDLLLIPGGLGT-RTLVSDIALRQWLVEQVTRSQNVFTVCTGTALLAMT-------SVLNGRKATTNKMAFE-------------------WVTSLNDNPQP-----KARWVFDGKFLTSSGVSAGTDAALFW------------ +-----------------------DDYETLDLHGPVEMLGHK-VQIKLVGD-KSIIRSYQ--------GP--------------KVVTDISMDSVT--PCDLFIVPGGLGT-RKLVEDEELMAWLRKQVSVSGKVFSICTGSALLAKA-------GILDGVNATTNKMAYQ-------------------WVTGLAGQVQP-----SARWVDDGKFLTSSGVSAGTDAALFY------------ +-----------------------DDYETLDLHGPVEMLGHS-VQILLVGA-KSIIRSYQ--------GP--------------KVVTDISMEQVT--PCDLLIVPGGIGT-RTLVEDSELLSWLQAQEKVSKKVFSICTGSALLAKA-------GILDGVNATTNKMAYQ-------------------WVTSLSQRVQP-----SARWVDEGKFLTSSGVSAGTDAALFY------------ +-----------------------DDYETLDLHGPIEMLGHP-TEIKLVAA-KEIVSSYQ--------GP--------------RVLADCLTEQTY--DCDLLLIPGGLGT-RTLVNDTELRQWLIAQIARSQNVFTICTGTALLAMT-------SVLNDRKATTNKMAYE-------------------WVTSLNDNPQP-----KARWVFDGKFLTSSGVSAGTDAALFW------------ +-----------------------DDYETLDLHGPIEMLGHP-VEIKLVGP-TEFVKSYQ--------GP--------------RVVADVLMDSTY--DCDLLLIPGGLGT-RTLVDNVPMLQWLAAQVECSEKVFSICTGSALLAKT-------TKLSGVTATTNKMAYK-------------------WVTSLAENVQP-----KARWVDDGKFLTSSGVSAGTDAALYW------------ +-----------------------DDYETLDLHGPLEMLGHP-VEITLIGP-QSIVRSYQ--------GP--------------RVVADRQLDEVV--ECDLLLVPGGMGT-RKLVDDTRLLDWLRRQVKVSNKVFSVCTGAALLAKA-------DLLDGVSATTNKMAYT-------------------WVTGLNDKVQP-----SARWVDDGRFLTSSGVSAGIDAALFY------------ +-----------------------EGFELLDVFGPLEMFGMKDVEIVMIAD-KGPVRSGA--------GP--------------QTIADHGFADAP--KLDIVMIPGGLGT-RREVNNPDFLAAVRTLAQDTPQVATICTGSGLLAKT-------GLIDGVKATSNKMAWA-------------------WATAQGAKVIP-----HARWVEDGKYISSSGISAGTDMALGL------------ +-----------------------EGFELLDVFGPLEMFGLAEFEIRLISE-TGVVASRQ--------GP--------------KSVCDDSFQSAP--AIDVLLVPGGIGT-RREVNNPVLLDWLNERSQLAELVASVCTGSALLAKA-------GVLDGLRATSNKLAFA-------------------WASAQSEKVQQ-----QARWVEDGKIFSSSGVSAGIDMALAV------------ +-----------------------DGFQLLDTFGPLEMFGAKDVDILMIGE-RGIVKSSA--------GP--------------AVVVDRTFDEIT--TLDMLLIPGGMGT-RREVNNQPFVDAFRKLAERTPHVASICTGAAILART-------GLIDGLKATTNKRAFK-------------------WATSQRDKVIK-----QARWVEDGKFFTSAGVSAGTDMALAL------------ +-----------------------EGFELLDVFGPLEMFGMNDVDTVLIAE-KGPVASRT--------GP--------------KTVADVSFADAP--KLDIVMVPGGSGT-RREVDNPAFLSAMTQLAEATPQVASICTGSGLLAKA-------GLLNGMRATSNKMAWQ-------------------WATAQGKEVVP-----RARWVEDGRFITSSGVSAGTDMALAL------------ +-----------------------EGFELLDIFGPLEMFGMNDISTVLIAD-KGPVTSRT--------GP--------------ATIADVSFADAP--KLDIVMIPGGSGT-RREVNNPAFLEAVKNLAEATPQVATVCTGSAVLAKT-------GLLDGVKATSNKMAWQ-------------------WATAQGAKVLP-----KARWVEDGKYISSSGISAGIDMALAL------------ +-----------------------EGFELLDVFGPLEMFGMKDVEIVTIAE-KGPVKSGA--------GP--------------AAMADHGFADAP--RLDIVMIPGGIGT-RREVDNPAFMQAIRILAEATPQVATICTGAGVLAKT-------GLLDGHKATTNKMAWK-------------------WATAQGAKVVP-----KARWVDDGKFISSSGVSAGTDMALAL------------ +-----------------------EGVEELDFTAPYEVFCADYVDVRYVSVDDRTVTAAY--------GT--------------RVRVDHRWAP-E--EADVLVVPGGGYA-RP--ADPGVHAEIRRGSRPGLTVSALCTGVMLLSAA-------GLTRGRPCTTHHRARA-------------------DLEQQGGVL-K-----NARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------DGVEEQDFVAPVEVLGLGRLTTTLVTPHRGTVTCTY--------GT--------------KVQVAEGWAP-E--KADVLVVPGGGYT-DK--TGPGVNRLAADQAAADVLRAGICTGTMVLSAA-------GLTKGRNATTHTGAKA-------------------ELAAQGATV-V-----NARVVDDGDLITGGGITSGLDVALWL------------ +-----------------------DGVEEQDFAGPYEVFSAGMTDVSYVRVDGGVVRAAY--------GT--------------KVEVERGWSP-Q--DADIIVVPGGGYA-KR--KGPGIWAEIDRKPRKGLTLASLCTGTLLLGAA-------GLVRGRPCTTHHGAAD-------------------TLVQQGGVL-K-----KARVVDDGDVVTSGGITSGLDLALWL------------ +-----------------------DGAEEQDFIGPYEVFSAGYVRMTYAALGGRTVTAAH--------GT--------------RIVVDSGWSP-E--STDILLVPGGGWN--R--EGPGVTEEIKRGVQTGLTIASVCTGAMLLSAA-------KLTQGRSCTTHHLAQQ-------------------ELVKEGGIV-K-----DARVVDDGDLVTSGGVTSGLDLALWL------------ +-----------------------DGVEELDFTAPYELFSAGYVDVRYVTLDGRTVEAAY--------GT--------------RLRVDHGWAP-R--DADLLVVPGGGYA-RR--EDPGVWAEIRRGTRPGLTVSALCTGVMLLSAA-------GLTKGRPCTTHHRARA-------------------DLEEQGGVL-K-----NARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------DGVEELDFAAPYEVFSARFVEVRYVTTSRGFVRASY--------GT--------------QVGVEYGWAP-Q--EADVVVVPGGGYA-RR--EDPGVWAEVRRGPRPGLTVAALCTGVMLLSAA-------GLTRGRPCTTHHKARP-------------------DLEREGGVL-K-----NARVVDDGDLVTAGGITSGLELALWL------------ +-----------------------EGVEELDLAAPYEVFAADYVEVRYVALDGRTVTAAY--------GT--------------RLRADHAWAP-E--EADLLVVPGGGYA-RR--EAPGVWAEIRRGPRPGLTISALCTGVMLLSAA-------GLTDGRPCTTHHRAKA-------------------DLERQGGVL-K-----NARVVDDGDLVTAGGVTSGLDLALRL------------ +-----------------------DGVEELDLSAPYEVLAADYVDVRYVALGGRTVRAAF--------GT--------------TLRVDHAWAP-E--QADLLVVPGGGYA-RR--DDPGVWAEIRRGPRPGLTISALCTGVMLLSAA-------GLTRGRPCTTHHRARQ-------------------DLEEQGGLL-K-----NARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------DGVEELDFAAPYEVFSARFVEVRYVTTSRGFVRASY--------GT--------------RVGVEHGWAP-Q--EADVVVVPGGGYG-RR--EDPGVWAEIRRGPRPGLTVAALCTGVMLLSAA-------GLTRGRPCTTHHKARP-------------------DLEREGGVL-K-----DARVVDDGDLVTAGGITSGLELALWL------------ +-----------------------DGVEELDLAAPYEVLAADHVDVRYVALDGRTVTAAF--------GT--------------RLRADRAWAP-E--QADVLVVPGGGYA-RR--DQPGVWAEIQRGPRPGLTISALCTGVMLLSAA-------GLTHGRPCTTHHRAKA-------------------DLERQGGVL-K-----NARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------EGVEELDFAAPYEVFCARFVDVRYVTAGAGTVRAAY--------GT--------------RVAVDGAWDP-R--AADILLVPGGGYA-RP--DAPGVGAEIRSGPRPGLTVAGVCTGTMLLAAA-------GLTANRPCTTHHKARP-------------------DLEKQGGLL-K-----NARVVDDGDLVTAGGITSGLDLALWL------------ +-----------------------DGVEELDFAAPYEVFAARFVEVRYVSATRPGITGAY--------GT--------------AVGGIGRWAP-G--EADILVVPGGGYG-RP--DSPGVRAEIERGARPGLTIGAVCTGALLCSAA-------GLTRNRPCTTHHRARA-------------------DLERQGGVL-K-----NARVVDDGDLVTAGGITSGLELGLWL------------ +-----------------------DGVEELDFAAPYEVFSARFVDVRYVTTTGGVVTAAY--------GT--------------RVEVEHAWAP-R--SADILLVPGGGYG-RQ--DGPGVWAEIRGGVRPGLTVSAVCTGAMLLAAA-------GLTGNRPCTTHHKARP-------------------DLEKQGGLL-K-----NARVVDDGDLVTAGGITSGLELALWL------------ +-----------------------DGVEELDFAAPYEVFCARFVDVRYVTTTGGTVHAAY--------GT--------------RVRVEHAWAP-G--SADVLLVPGGGYA-RR--DSPGVWAEIRSGVRPGLTLGAVCTGTMLLSAA-------GLTRNRPCTTHHRARP-------------------DLEQQGGLL-K-----NARVVDDGDLVTAGGITSGLDLALWL------------ +-----------------------DAVEEQDFAGPIEVLGIADIKQSFVTADGRTVRTSS--------GM--------------YIDVRDPWAP-Q--DADVLLVPGGGYG-----KGSGVDDEIKRGERPGLIMGGICTGVMVMSAA-------KITRGRPCTTHFAARD-------------------DLAKQGGKL-T-----YGRVVDDGDLITCGGVTSGLDLALWL------------ +-----------------------EGVAEIDALATYAVFANQRVEPYLVTADGTQVTGCY--------GT--------------TFAELVPWAP-E--SARVLAVSGGW-----------VLEEIERGGGEQLVLAGIDSGSLLLGAA-------GLIAGRPATTHRADLE-------------------RLAE-WAEV-I-----DARVVDDGDLVTCGGWFAGTDLAYWL------------ +-----------------------DGVEEQDFTGTVAAFGVDDVQVSYVSAEGGAVTTAS--------GA--------------EIVVRAPWSP-D--SADLILVPGGGYG-----AGSPVDDQIRLGQRPGLVLASVCTGSLLLSAA-------GLTAGRPCTTHHVAKD-------------------DLAAQGARV-V-----GGRVVDDGDLVTAGGVTSGLDLGVWL------------ +-----------------------DGVEEQDFAGHVEVFGIGEVAQSFVHVEGRRVRTAA--------GM--------------EVVCRDAWSP-R--SADVIIVPGAGYG-----DGSALQREIRRGPRTGLVLGAVCTGTMLLSAA-------GLTAGRRCTTHHIAQE-------------------DLRREGAQV-V-----AGRVVDDGDLVTCGGVTSGIDLGIWL------------ +-----------------------DGVEEQDFAGHVEVLGIGEVKQSFVHAEGRRVTSAA--------GM--------------EIRCRDAWSP-R--SADVIVVPGAGYG-----DGSGLQREIRRGPRKGLVLGAVCTGTMLLSAA-------GLTAGRRCTTHHIARD-------------------ELRRDGGHV-V-----GGRVVDDGDLVTCGGVTSGIDLGIWL------------ +-----------------------EGAEDLDYVGPYDVLSRADIRTTLVSPYRTTITTAK--------GI--------------RVEVPRGWSP-Q--DADVLVVPGGGMH-NQ--PGSGLHRLIADKADAKPVKVGVCTGVMALSAA-------GITRGRPATTHTAAKP-------------------YLAEQGATV-I-----NARVVDDGDLVTCAGVTSGIDGAIWL------------ +-----------------------DGVEEQDFAGHIEVFGIGEIAQTFVTVDGRTVRTSA--------GM--------------EVVCRAPWSP-R--SADLIVVPGAGYG-----EGSGLQREVRRGRRPGLVLGGVCTGTMLLSAA-------GITNGRPCTTHHIATE-------------------DLAAQGGRV-V-----GGRVVDDGDLVTCGGVTSGIDLGIWL------------ +-----------------------EGAEDLDYVGPYDVLSRADIRTTLVSPYRTTITTAK--------GI--------------RVEVPRGWSP-Q--DADILIVPGGGMH-NQ--PGSGLHKLIADKAEAKLVKVGVCTGVMALSAA-------GITRGRPATTHASAKP-------------------YLAEQGATV-I-----NARVVDDGDLVTCAGITSGIDGAIWL------------ +-----------------------DGVEELDFAAPYEVFSAGFVEVRYVSATGRSVTAAY--------GT--------------TVRDLHRWAP-D--EADLLVVPGGGYA-RR--DSPGVWAETDRGSRPGLTLGALCTGVMLLAAA-------GLTRGRPCTTHHRAKA-------------------DLERRGGLV-K-----NARVVDDGDLVTAGGITSGLELALWL------------ +-----------------------DGVEEQDAIGPRDVFGHVQVETTLVRPSAGEVTCFF--------GT--------------RVTVPTAWDP-T--DTDLLIVPGGGDR-LI--HDPDVLRD----QEAGVIVAGVCTGVMVLSAA-------GLTKGRPCTTHHLAKT-------------------ELAAQGGKV-I-----DARVVDDGNLVTAGGVTSGIDLALWM------------ +-----------------------DGVEELDCIAPYEVLSAGRADIRYVTTGEGPVRCGH--------GT--------------EIQVRHRWAP-Q--EADLIVVPGGGYA-RR--DAPGVWAEVRSGPRSGLTISGVCTGTMLLSAA-------GLTRGRPCTTHHRAKA-------------------HLEEQGGDV-K-----NARVVDDGDLVTAGGITSGLELGLWL------------ +-----------------------DGVEELDFAAPYEVLSAGFVDVRYVSATGRTVTAAY--------GT--------------AVRGIRPWAP-D--EADLLVVPGGGYA-RR--DSPGVWAEIDRGPRPGLTVAALCTGVMLLSAA-------DLTKGRPCTTHHKAKP-------------------DLAQQGGLV-K-----DARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------DGVEELDVFGPLQVLGAAAVAYRLVTGGRGTVSARF--------GT--------------RIDVPDAFDP-A--EADVLVVPGGGFR-LR--NGPGIWAELKDGADERLTLYGLCTGVVLLHEA-------GVIRNRPCTTHTGAKQ-------------------YLRDQGADV-R-----DARVLDDGNLVCAGGVSAGIDGALHL------------ +-----------------------DGVEELDLFGPLEVFALAAVVPTLVTTGRGRVRAAF--------GT--------------QIEVPGRWDP-S--SADAVVVLGGGYR-KR--DGAGVWAEIDKG-RPGLTLVGVCTGVFLLHAA-------GLLDGRPCTTHVRAKQ-------------------DLRDLGHDV-R-----DARVVDDGDLVCAGGVSSGIDAALWL------------ +-----------------------DGVEELDFAAPYEVFSAGFVEVRYVSATGRTVTAAY--------GT--------------TVRGLRPWAP-D--EADLLVVPGGGYA-RR--DSPGVWAEIDRGVRSGLTISALCTGVMLLSAV-------GLTKGRPCTTHHKARP-------------------DLQQQGGLL-K-----NARVVDDGDLVTAGGVTSGLDLALWL------------ +-----------------------DGVEELDYIAPYEVFSAAMVEVRYVTTGRRMIRCGY--------GT--------------GIQVKYRWSP-A--EADLIVVPGGGYA-RR--EGPGIWSEIDSGPRKGLTISSLCTGALLLSAA-------GLTKGRPCTTHHGAKA-------------------YLEEQGGVV-K-----NARVVDDGDLVTAGGITSGLELGLWL------------ +-----------------------NGVGLGDMNGPIDVFTKGNYHVYTVALKPGTVTTQA--------GGL-------------KFMPDYTADQMP--QPDILVIPGGSVGLDSMRYNQPVLNFIKQYEKA-QVLMSICTAAYFVGQT-------GAFDGHKVTTHFFQAE-------------------DLQKQFPKSIQ-----DVRFVDDGKLVTASGVTTGIDASLHL------------ +-----------------------PGVGLGDLQGPVDIFTKNGYHVYTVALKAGVVTTQG--------GTL-------------KFTPDYTATDMP--KPDILVIPGGTVGLDSMRHDQQVIGFIQQYDKV-DVLMSICTAAYFVGQT-------GAFDGHKVTTHFFQAD-------------------DLQLQFPKSIR-----DVRFVDEGKLVTASGVTSGIDASLHL------------ +-----------------------DNIVVQDFAGPIEVFSKKKYQVFTVGFDKNPIRTEQ--------DGL-------------EIVPDYAISKMP--EADYLLLPGASMPVNELMQHDDLSAFIKNWAQQNTKTVTICTGAYLLANT-------GALDGKKATTHFFVAN-------------------DFAQLFPAVIK-----DTRFVDEGKYITSSGVTSGIDAALYI------------ +-----------------------DGVEIVDTGGPIDVFVKNNYKIYTVSATNKQIIMDG--------GTV-------------NLVSQYTIYDAP--QSDILIIPGTSPEIRTISKDKNMMDWIVKQEKT-QITMSVCTGGLILANT-------GLLDGHSATTHHWSLD-------------------EMR-LHKKIKQ-----EARFVADGKFLTGAGITSGIDTALEA------------ +-----------------------DGVEIVDTGGPMDVFIKNNYNIYTVSASAKSTLMDG--------GTF-------------NMLSKYSINDAP--QADILIIPGTSPEIHKVSADHKMMNWIVKQEKT-IMTMSVCTGGLILANT-------GLLDGRSATTHHWSLD-------------------ELR-SHPKIQE-----TTRFVVDGKFLTGAGVTSGIDVALQA------------ +-----------------------DDVEELDAVGPWEVLTYARVRVWTVAR-RREVRCAK--------GL--------------TVLADHTPDDAP--PATVLVHPGGAGT-RPLMRDEDWLAWVREQRAHVPLMTSVCTGSLVYAAA-------GLLRDRPATTYWGALD-------------------ELRAADPTVRS-----DDRFVDDGDVITSSGVSAGIDMALHL------------ +-----------------------PGFTLLDLVGPHTVFTGMHTDIQLVWKSKSPVESDT--------G-I-------------TIQSTATFDECPD-DLDILFAPGGSLPTVELMDDAHVTDFLARKGERARWVTSVCTGSLLLGAA-------GLLKGYRATSHWVVRD-------------------VLAEMGARP-V-----EARVVEDRNRITAGGVTAGIDFGLRL------------ +-----------------------PKMILLDLVGPLTVFN-MGARIHLVGRTPAPVASEV--------G-I-------------PVTPTTTYPDCPR-DVDVLFVPGGLGGTVDLMDDPGTIAFLREMGERARFVTAVCTGTLLLGAA-------GLIRSKRATTHWYVRD-------------------LLPLFGGVP-T-----EERVVEDGNLVTGGGATAGVDFGLTL------------ +-----------------------PQMVALDLVGPLSVFKVARFDTMLVGKRSEAVPTAE--------G-L-------------PIAATHTFEDCPR-ELDVLFVPGGIMGTIAAMNDPQVMAFLADRGARARWVTSVCTGSLALAAA-------GLLNGYDATSYWAVAD-------------------LLPLMGARH-V-----DQRVVTDRNRMTGGGVTAGLDFALTL------------ +-----------------------PGMTVMDLIGPQSMFAAMGARIHLVAKTLDPVTSDG--------G-V-------------TITPDATFDTCPR-DLTVLFTPGGTDGTIKAATDPATLAFMADRASRATYVTSVCSGSLILGAA-------GLLKGYRATSHWSCRD-------------------ALAGFGAIP-T-----DARVVRDRNRITGAGVTAGLDFGLSM------------ +-----------------------PGMILLDLTGPLTVFN-MQADVRLIAGSMVPVATDV--------G-I-------------PVSPAHNFETAPA-ELDVLFVPGGLKGTVEGMNDPRTLDFVAARGATARFVTSVCTGSLLLGAA-------GLLKGYKATSHWYVRD-------------------LLPLMGAAM-V-----ADRVVTDRNRITAGGVTAGIDFGLSL------------ +-----------------------PDMTALDLVAPQLVFATGDADTHLVWKDLSPVTTDS--------G-L-------------KILPSTTFADAPA-APDILFVPGGLKGTTALLRDEDTLRFLRERGEVARWVTGVCTGVLLLGAA-------GLLRGHRATAHWYVRD-------------------LLPIFDATP-V-----AQRVVVDRNRVTGGGVTAGMDMALTL------------ +-----------------------DGVTQQDYIGPISALG-PHCKVHLLHTSSEAVRSDLR-------F---------------GILPSSTFADV-Q-RVDILLVPGAPTHYIAALQDDGLMEAIARLGRGARYVTSVCTGAVLLGCA-------GLLDGYRATTHWTALP-------------------VLEAMGIET-V-----RQRVVHDRNRLTGGGVTAGLDFGLTL------------ +-----------------------PGMTALDLVGPHYALASPGANVQLAAAKPGKIVCDR--------G-M-------------SLFAESSLADVPA-DLDMLFLPGGAPGTIAAMQDPAFLAFLADRGKRARFVTSVCTGSLVLAAA-------GLLKGYQATCHWAFRD-------------------ILPMLGATP-V-----AQRVVTDRNRITAGGVTAGIDFGLRL------------ +-----------------------PGMILQDLVGPQTVFS-LQADTRLVWKDKNPVATDV--------G-I-------------ALSANDTFDTCPA-ELDVLFVPGGLGGSIACMKDADVIGFVESRGARARYVTSVCTGSLVLAAA-------GLLRGYQATSHWYVRD-------------------LLPLMGATL-K-----AERVVEDRNRLTAGGVTSGIDFGLTL------------ +-----------------------PGMILLDLTGPLTVFN-MQADIHLIGASMAPVMTDV--------G-I-------------PVTPTHSFETAAT-GLDVLFVPGGLKGTVDGMNDPRTIDFVARRGETARFVTSVCTGALLLGAA-------GLLKGYKATSHWYVRD-------------------LLPLMGATM-I-----ADRVVSDRNRITAGGVTAGIDFGLAL------------ +-----------------------PKMILLDLLGPMTVFN-TRGKIHLVWKDQTPVSTDV--------G-I-------------PVTATTTFKKCPR-NVDVFFIPGGLVGSTELMEDAETLDFVREMAAGAKYVTAVCTGSLVLGAA-------GLLKGKRATTLWNVRD-------------------LLPTFGAIS-V-----NERVVEDGNLITGGGTTAGIDFGLSV------------ +-----------------------PKFTALDLIGPHQILASPGVHVDVVGRTTEPVVTDR--------Q-I-------------CITPAKSFSECEA-DYDIVLVPGGISTH-LMVEDAETLEFLARIGENATYVTSVCTGSVILAAA-------GLLKGYHATSHWAYRE-------------------ILADYGAIP-S-----KARFVVDRNRVTGGGVTAGIDFGLQL------------ +-----------------------PKMILLDLTGPLTVFN-TMGKTHLVWKDKNPVSTDV--------G-I-------------SVAPTTTFAECPR-DVDVLFVPGGLAGTTALLDDSETLAFLSEMGARARFVTSVCTGSLALGAA-------GLLTGRRATSHWYTRE-------------------LLPLFGATR-S-----DERVVEDGNLITGGGVTAGIDFGLTI------------ +-----------------------PGLTALDLVGPQTFLAGAPGSLHLVGAETGPVTSDT--------G-L-------------ALVATHSFATCPA-DLDVLFVPGGDGTP-AQMGHAALLAFLRDRAARAGWVVSVCTGSLILGAA-------GLLRGYRATSHWSVRD-------------------ALPLLGAEP-V-----AERVVFDRNRVTAAGVSAGLDLGLAL------------ +-----------------------PGMTALDLVGPQALLAGAPGSLYCVAQAEGPVASDT--------G-L-------------SLVATHTFATCPP-DLDVLFVPGGDGTP-DQMRDAALLAFLRARAPRTAWVTSVCTGSLILGAA-------GLLRGYRATSHWCVRD-------------------ALPLLGAAP-V-----AERVVFDRNRATGAGISAGLDLALAL------------ +-----------------------DGVTQLDYIGPLTAFA-PHFRTYLLHHTLDAVTTDID-------A-V-------------MALPTATFDQV-D-HVDILLVPGAPNKHNRLLCDARFLAQLRRLGSGAQYITSVCTGSLLLARA-------GLLDGFKATSHWSALE-------------------VLAAMGIET-V-----KQRVVHDRNRITAGGVTAGIDFGLTL------------ +-----------------------PNMTALDLVAPQLVMSKPNSVVHLIAESQSPVMSDS--------D-L-------------AIVPTMTFEQCPD-ELDVFFVPGGPKGTLTALQNDRLLDFVSHRGSRARYITSVCTGSVLLGAA-------GLLKGYKAASYWGTLD-------------------MLPVFGATP-V-----SDRVVKDRNRITGGGITAGLDFGLEL------------ +-----------------------PGMTALDVVGPQGLLAGAPDTLHLVAQATGPVLSDT--------G-L-------------SLVATTSFADCPT-ELDVLFVPGGDGTT-AQMRDAATLAFLRDRASRARWVTSVCTGSLILGAA-------GLLKGYRATSHWCARD-------------------TLPLLGAIP-V-----DDRVVFDGNRVTAAGVSAGLDFALAL------------ +-----------------------PGLTLLDLVGPQTALNS-SCDIHLIWKNKDPMISDT--------G-V-------------VVQADTSLDECPD-DLDVLFIPGGPGQV-AVMRDDAMLRFIADRGERAKYVTSVCSGALVLGAA-------GLLQGYEAATHWAAMP-------------------LLPLFGAKP-V-----DKRVVKDRNRMTGGGVTAGLDFGLTL------------ +-----------------------PEFTALDMVGPHHMLTGMGATVHIVAKTRDPVKSDT--------G-L-------------TFVPSATFEECPA-DLDIICVPGGTQGTLAAMQDEATIRFLRDRGSRARFVTSVCTGSLVLGAA-------GLLDGYRATSHWAAKP-------------------VLPVFGAIP-T-----EGRVVRDRNRITGGGVTAGIDFGLSL------------ +-----------------------PEFTALDMVGPHAMLTGLGATTHIVGKSRDVVKSDT--------G-L-------------AFQPSASFDECPL-DLDIICVPGGATGTLAAMQDDSTLRFLKDRGSRAKFVTSVCTGSLLLGAA-------GLLTGYNATSHWATIP-------------------LLKLFGATP-S-----DDRIVRDRNRITAGGVTSGIDFGLSL------------ +-----------------------PEFTALDMVGAQAMLASFGATTHIVAKTRDIVKSDN--------G-L-------------QFQPSATFDECPR-DLDIISVPGGAAGTLAAMQDDGTLRFLRDRGSRARFVTSVCTGSLLLGAA-------GLLTGYRATSHWATVP-------------------LLPLFGATA-S-----EARIVRDRNRITAGGVTAGIDFGLSL------------ +-----------------------PGFTALDLVGPHYMLTSMGATTHVVARSRDPVVSDT--------G-L-------------TLVPSATFAEVPA-DLDILFVPGGTSGTLAAMRDPATMDFLADRGRSARFVTSVCTGSLLLGAA-------GLLDGYEATSHWMTRS-------------------LLPIFGAKP-V-----DRRVVRDRNRITGAGVTAGVDFGLAM------------ +-----------------------PEFTALDLVGPHYMFTSWGAKVHLVAASKEPVRSDA--------G-L-------------SFIPDLTLAEAPA-DLDILFVPGGSQGTLKVMQDPKQIAWIADRARRAKLIASVCTGAMILGQA-------GLLRGKRATTHWATHA-------------------LLKDFGAVP-V-----DERVVWDGTLVTGAGVSAGLDLGLSV------------ +-----------------------PEFTALDMVGPHYMFTNMGATTHVVAKTRDPVRSDT--------G-L-------------VFTPSASFEDCPK-DLDIICVPGGSNGTLAAMQDEATVSFIKDRGSRARFVTSVCTGSLILGAA-------GLLTGYKATSHWAAKS-------------------LLPIFGAVP-T-----DGRIVQDRNRITGGGVTAGIDFGLKL------------ +-----------------------PDMTALDLVGPQLIFATPPVDVHVVWKDQQPVMTDS--------G-L-------------AVMPTSTLDQAPA-TPDVLFVPGGLKGTTALLSDPQVLSFLRSRGSSARYIAGVCTGGLLLGAA-------GLLRGYQATAHWYVRD-------------------LLPVFDAIA-V-----DRRVVQDRNRITGGGVTAGIDLALTL------------ +-----------------------PGMFLQDLVGPLTVFEAMNKEIHLLWKDLEPVGNESPGP---AAL-I-------------PVKPTTTFAQCPE-QLDVLFVPGGVPGTFTMMEDPEVLAFLKAKGQTARYVTSVCTGSLILGAA-------GLLKGYKATSYWDTRD-------------------VLKELGAIP-T-----RGRIVVDRNRITGGGVTAGIDFGLKL------------ +-----------------------DGLVPLDLIGPLSVLGAGRARLHFVGPDLPI-PGGA--------G--------------------LQWVPLP--RPDVLVVPGPGQP-SILMQDPAILDYI---HRHTRITFGICTGVLLMAAA-------GILRGRAATTYWAFAD-------------------ELPLSGARF-K-----RRRWVVDGRIVTSAGVSAGMDAALVV------------ +-----------------------DGYEPLDVVGPYEVLAYPGASVRFVGAEKGPVKDAL--------GSL-------------PTYVPATYSEVE--RCDVLLIPGGRSVE-AMVADADFLAWVRRIHARTRFTTSVCTGSLVLGAA-------GLLKGLTATTHWSGAE-------------------ALESYGAAY-T-----PQRTVRQGKVITSAGVSSGIDMALTL------------ +-----------------------PNGTLLDFAGPHEILTLPNVKVRFASPAGGLVTLEN--------G-V-------------VFGPTEKLTDVT--DVDVICVPGGLNL--SAMMKPEILAHIKRLSETAKYVTSVCTGSIILAAS-------GALKGKRSACHWAFLN-------------------DLKKYGAIP-D-----PSRIVKDGRFISGGGVTAGIDFGLAI------------ +-----------------------PNGTLLDFAGPNEILSRPNTKVRFASPDGGLVTLEK--------G-V-------------TFGPTEKLSDIE--RVDVICVPGALDL--SAMMKPEILAHIRRLSESARYVTSVCTGSIILAAA-------GVLKGKRSACHWAFLN-------------------VLKKYGAIP-D-----PARIVKDGRFMSGGGVTAGIDFGVAI------------ +-----------------------PNGTLLDFAGPNEILSLPDTKVRFASPAGGLVTLEK--------G-V-------------IFGPTEKLSDVQ--KVDVICVPGALDL--SAMMKPEILRHVRRLSETARYVTSVCTGSIILAAS-------GVLKGKRSACHWAFLN-------------------VLKEYGAIP-D-----PARIVKDGRFMSGGGVTAGIDFGMAI------------ +-----------------------DGLDQIDLTGPFEVLSRPGATHRLYARTAEPVRDVQ--------G-L-------------RLVPDATLHDAP--PLDILHVPGGPGQQ-ALMHDQVVLDWLRAQAAGARKVFSVCTGALLLGAA-------GLLRDRRATTHWNSFH-------------------LLPLFGATP-V-----DERVVVDGDWIFAAGVTSGIDGALRL------------ +-----------------------EGLDQIDLTGPFEVLSRPNATYRVYGVTADPVRDLR--------G-L-------------RLTPDAPIADAP--QLDVLHVPGGFGQQ-ALMEDANVLDWIRRQAAHA-RIFSVCTGALICGAA-------GLLMGRRATTHWASFH-------------------LLPYFGAIP-V-----NERVVVDGDWVFAAGVTAGIDGALRL------------ +-----------------------DDMDQIDFTGPFEVLSRPGGHHRVYGITGQPVRDVR--------G-L-------------TIVPDAAIGDAP--ALDVLHVPGGRGVD-VLMENEEVLAWLRKQSG--NVVLSVCTGALQLGAA-------GLLAGRRATTHWASLH-------------------LLPEFGAEA-V-----DERVVVDGDWIFAAGVTSGIDGALTL------------ +-----------------------EGLDQIDLTGPFEILSRPNSTYRLYGKTTDTVRDIR--------G-L-------------RLAADALLADAP--QLDVLHVPGGYGQE-MLMEDEEVLSWVRRQAAGAKCVLSVCTGALICGAA-------GLLKGRRATTHWSAFE-------------------LLPIFGAIP-V-----NQRVVADGNMVFAAGVTAGIDGGLRV------------ +-----------------------EGIDQIDLTGPFEVLSRPNATYRVYGKTAETVRDVR--------G-L-------------RLTPDAAIEDAP--QLDVLHVPGGFGQE-DLMEDEAVLAWLRRQASGARSVFSVCTGALLCGAA-------GLLKGRRATTHWASFD-------------------LLPYFGAIP-V-----DQRVIVDGTWVFAAGVTAGIDGALRL------------ +-----------------------EELDQIDLTGPFEVLSRPNATYRIYAKTTDTLRDIR--------G-L-------------KLVADAPIADAP--QLDVLHIAGGYGQE-ALMHDEEVLGWIRRQAEGALCVFSVCTGALLCGAA-------GLLKGRRATTHWSAHH-------------------LLPLFGAIP-V-----DERVVVDGNLVCAAGVTAGIDGALRV------------ +-----------------------DGLDQIDLTGPFEVLSRPNTTYRVYAKTTDPVRDVK--------C-L-------------KLTPDATLAEAP--QLDVLHVPGGFGQE-ALMDDEEVLGWLQQQAAGAGSVFSVCTGALLLGAA-------GLLRGRRATTHWASFH-------------------LLPLFGATA-V-----NERVVVDGRWVFAAGVTAGIDGALRL------------ +-----------------------PGLDQIDLTGPFEVLSAPNSTLHVAAKTRSPIKDFH--------G-L-------------SLVADMTYDEVP--ELDVLHVPGGPGQQ-ALMEDEETLDFIRKHASKATYVFSVCTGALLCGAA-------GLLRGKKATTHWASQH-------------------LLPYFGATP-V-----DQRIVIDGNWVFAAGVTSGIDGALHL------------ +-----------------------EGLDQIDLTGPFEVLSRPNSTYKIYARTAEPVRDLK--------G-L-------------RLVPDATLADAP--QLDVLHIPGGFGQE-ALMDNDEVLGWIRQQAAGALSVFSVCTGALLCGAA-------GLLMGRRATTHWASFH-------------------LLPFFGAIP-V-----NERVVVDGNWVFAAGVTAGIDGALRL------------ +-----------------------DDMDQIDFTGPYEVLASSNVTYTTYGLSSQPVRDWR--------G-L-------------GLLPDAVLEDAP--QLDVLHVPGGPGQQ-AHMEDQRLLNWLQRQASGARCVLSVCTGALLLGAA-------GLLHGRRATTHWGSLD-------------------VLPIFGATV-V-----PERVVTDGSFVFAAGVTAGIDAALMV------------ +-----------------------EGLDQIDLTGPFEVLSRPNSTYRLYGKTSDGVRDIR--------G-L-------------RLAPDASLADAP--KLDVLHVPGGYGQE-ALMEDVEVISWVRQQAEGAVCVFSVCTGALICGAA-------GLLKGRRATTHWSAFE-------------------LLPIFGALP-V-----NERVVMDGNMVFAAGVTAGIDGALRV------------ +-----------------------DDLDQIDLTGPFEVLSRPNATYRLYAPTAAPVKDIK--------G-L-------------RITPDATLADAP--QLDVLHVPGGFGQE-RLMENAEVLDWIARQAKGAHAVFSVCTGALLCGAA-------GLLVGRKATTHWASFH-------------------LLPLFGATP-V-----NARVVKDGNYIFAAGVTAGIDGALQL------------ +-----------------------EDVDQIDLTGPFEVLSRPNSTYRIYAKTMEPVRDLK--------G-L-------------RLTPDATLAEAP--PLDVLHVPGGFGQE-ALMEDAEVLGWIRQQAAGACSIFSVCTGALLCGAA-------GLLKGRRATTHWASFH-------------------LLPYFGATP-V-----NERVVVDGSYVFAAGVTAGIDGALRL------------ +-----------------------PHIDQLDFTGPFEVLSRPDSSFHVLWKERTPVRDVR--------G-L-------------VLTPDMTFAEAP--RLDVLVVPGGYGQE-ALMDDDAVLSFIRGSAAEAKFVLSVCTGALTCGAA-------GLLKGVRATTHWASFH-------------------LLQYFGAIP-V-----DARVVVDGRFISTAGVSAGIDGAFRV------------ +-----------------------PGLDQTDFTAPFEVLSRPNSTFHILWKEKMPVKDVK--------G-L-------------ILTPEKTLAESP--PLDLLLIPGGYGQE-ALMEDETVLCFIREQAVNAKYVFSVCTGALICGAA-------GLLKGVRATTHWSAFH-------------------LLEYFGAIP-V-----DERVAIDGKIVSAGGVTAGIDGALRV------------ +-----------------------EGLDQIDLTGPFEVFARPNTTTRLYGLTDAPVTDVG--------G-L-------------RLTPDGSVLDAP--QLDVLHIPGGGGQE-ALMRDEALLHWIRRQAEGAKILFSVCTGALICGAA-------GLLKGRKATTYWTVQH-------------------LLPLFGATP-V-----DARVVVDGNLVCAGGVTSGIDGALRV------------ +-----------------------EGLDQIDLTGPFEVLSRPNSTYRVYAPGPEPVRDVR--------G-L-------------RMLPDATLAEAP--RLDVLHVPGGTGQE-ALMRDPAVLGWIRDQAAGAGHVLSVCTGALILGAA-------GLLVGRRATTYWNAVH-------------------LLPFFGAEP-V-----DARVVIDRTWVFAAGVTAGIDGALQL------------ +-----------------------EGLDQIDLTGPFEVLSRPNSTYRIYGPTLDPVRDVR--------G-L-------------RITPDATLAEAP--RLDVLHIPGGQGQE-ALMRDAAVLGWIRSQAAGASHVFSVCTGALLLGAA-------GLLVGRRATTYWNAVH-------------------LLPWFGAEA-V-----DARVVIDRTWLFAAGVTAGIDGALRL------------ +-----------------------DRITQLDATAPIEVFAKGWTVFTV-APERRLVTSGS--------G-L-------------KIMPDYDYESAP--QADILCVPGGGGVN-PLLTDTATLNFVRETAASAIYVTSVCTGSLILGAA-------GLLRGKHATTHWASHH-------------------FLESFGAIP-V-----KERVVVDGRLITGGGVTAGVDFAFTV------------ +-----------------------DRFTTLDAIGPYELLGRPGVETVFVARRPGPVRGDQ--------GSV-------------ALVADAALAEVT--APDIVLVPGGPGSR-EVMRDEEILDWVRTADAATTWTTSVCTGSHILAAA-------GLLAGRRATSYWPTLD-------------------ELVPFGAEP-T-----GERVVFDGKYVTAAGVSSGIDMALHL------------ +-----------------------DGGTLLDFAGPSEIFHRPNTNVRYASLNGGNVTLEF--------G-V-------------VYGKTERLADID--KTDVLLVPGGSDL--SAPMQPAYQAQIRRLAESAKHVTSVCNGSLVLAAT-------GVLKGKRSACHWAFVN-------------------KLAEYGAIP-V-----PDRFVEDGRFMSGGGVTAGIDFALRV------------ +-----------------------PGGTLLDFAGPSEVFHRPNTIIRFASREGGPVTLEY--------G-V-------------VFGRTDRLAEIE--KTDLLLVPGAPDM--TAAMTPEFLAQIRRLAESAKHVTSVCTGSLALAAA-------GILKGKRSACHWALVN-------------------KLAEYGAIP-V-----ADRFAEDGRFMSGGGVTSGIDFALRV------------ +-----------------------DGGTLLDFAGPSEIFHRPNTNVRYASLKGGNVTLEF--------G-V-------------VYGNTERLADIE--KTDLILVPGGSDL--SAPMHPEYLAQIRRLAEGAKHITSVCNGSLVLAAA-------GVLNGKRSACHWAFVN-------------------KLAEYGAIG-V-----PDRFVEDGRFMSGGGVTAGIDFAIRV------------ +-----------------------PGGTLLDFAGPSEIFHRPNTNVRYASLDGGYVPLEF--------G-V-------------MYGKTERLADIE--KAGLILVPGGSNL--TAPMQPAYQAQIRRLAERADHVTSVCNGSLVLAAT-------GILKGKRSACHWAFVN-------------------KLSEYGAIP-V-----PDRFVEDGRFMSGGGVTAGIDFALRV------------ +-----------------------NGGTLLDFAGPSEVFHRPNTNVRYASLNGGTVTLEF--------G-V-------------KYGHTERLADIR--ETDLIMVPGGSDM--TEAMHPEFLAQIRRLAESAKYITSVCTGSLSLAAA-------GVLKGKRSACHWAFVN-------------------NLAKYGAIP-V-----TDRFVEDGRFMSGGGVTSGIDFALRV------------ +-----------------------DGGTLLDFAGPSEIFHRPNTQVRYASVKGGNVTLEF--------G-V-------------VYGNTERLADIE--KTDLILVPGGSDL--SVPMQPEYQKQIRRLAESAKHVTSVCNGSLVLAAT-------GILNGKKSACHWAFIN-------------------KLGEYGAIA-V-----PDRFVEDGRFMSGGGVTAGIDFALRV------------ +-----------------------PGIDQIDFTGPFEVLVRPGAKIRIIGTQADPVRDYN--------G-L-------------VLTPEMTLAEAP--ELDLLVVPGGPGQQ-ALMQNEQLLQFIRRHHATGKPLFSVCTGALLCGGA-------GILDGRRATTHWSAID-------------------LLPYFGAIA-V-----DQRVVIDEEIVSAAGVTAGIDGALII------------ +------------------------NVQLLDVAGPNDAFAAPGANVHLIWKNRDLVTTTSGM----------------------EIRANTTFSEC--PKLDVLCIPGGGGVN-PLLQDDEVLEFVRRAAASTRYVTSVCTGSLVLGRA-------GLLNGKRATSHWNAVDF-------------------LPQLGAIPV------QERVVKDGTLYTAGGITSGIDFGLE------------- +------------------------GLTPLEAIGPFDILGKPKARVRVVGLESGLVHSRGTL----------------------GLRASAALEDV--HSAEILVVPGGAAA-DNLAHDPTLGAWLRRVVPTARAVLGVSTGSLILAGA-------GLLQGVEATTHWRALDL-------------------L-GFGAKV-------VRRIVTSGTLTTTVGAAAGMDAALA------------- +-------------------------MQLLDFAGPYDVFTTNHITVHLIGETLEPIKTTNHI----------------------RLNPQFDCNTV--PKLDILCIPGGKGV-NALLENETVLKFIQSQAQTTHYISSICTGSLVLGAA-------GVLKGYKATSHWSAVEY-------------------L-YFSAIP-------KDRVVIDKNIITAGGITAGIDFGLF------------- +------------------------RMEELDFVGPYEVFGMEEVCPRVLGADLSPLRAYHGL----------------------RILPETSLEEA--PKLDLLLVPGGDGR-KEASRDPVVLDFLRRTARSGALVASVCTGAFVLAAA-------GLLEGKEATTHHHFYDE-------------------LGTFPGIRL------VRRWVRDGNVATAGGVTCGVDLSLA------------- +------------------------GMTALDVVGPQALLAGAGPSFHLVAEI-GPVASD-GL----------------------EIVATADFETC--ADLDVLIVPGGDGTPD-QMRNERLLAFLRDRAGRAAWVTSVCTGSLILGAA-------GLLTGYRATSHWCVRDG-------------------VPLFGAIP-------VERVVFDRNRVTSAGISAGLDFALA------------- +------------------------GVTQLDFTGPLEFLSKPRARCLLASSRGGDIRADGGV----------------------VFSGIARLADI--ERCDLLCVPGGLGTM-EAMEDAELLGQLRRLAAGADYLSSVCTGSLLLGAA-------GLLKGRRAACHWAWLDS-------------------LVAFGAHPC------PDRVVVDGKLFSGGGVTAGIDMALT------------- +------------------------EITAIDYVAPADLLVRPGAQLHLVWKHTDPVRTELGW----------------------EFRPTASFDTC--GQLDMLVVPGGPGIE-ALLSDGETLAFLARQAQGAQWIVGICTGPLVLGAA-------GLLQGYRATCHWGSHEL-------------------LSLVGATPV------DERVVVDRNRITGAGMTSGIDCALQ------------- +------------------------AITQLDLTAPWEAFRHPDAQVHLLWKETGPVMAEGGM----------------------RIEADTKLSEA--PRLDVICIPGGRGID-ALLEDQEVLTWLVKQAETARFICSVCTGALVLGAA-------GLLRGKKATTYWAAHDF-------------------LTAFGAEPV------QARVVQDGKLLTGGGVTAGLDLALS------------- +------------------------GVTQLDLTGPYEVLVRPGFQCELVAKQAAPVRSDRGL----------------------MLVPTTTIAQA--SPCDLLVVPGGPGTD-AALVDPEWIAFVREQAKQARWVFGICTGSLLLGAA-------GLLHGRRASGHWLARDL-------------------LTQFDAIPM------DDRTTIDGKYFTSGGVTAGIDMALR------------- +------------------------GMTTLDIVGPQTVFSASGIKLHRIWKALEPIEADDGM----------------------VVVPDTTFADC--PSLDVLCIGGG-KQM-MIVDDPEVLEFLKKQGNTAQFITSVCGGSMFLAKA-------GLLQGYRAATHWAMREE-------------------LAKLGVEVG------TERVIVDGNRISGGGVTAGIDFGLT------------- +-------------------------MVMLDLIGPMTIFNVLGTHIDLVWKEKIPISTE-GL----------------------SITPSKTFAEA--DAPDVLFIPGGLMG-TDCMNDPQVMDFLRGRGEKAKWVTAICTGTLTLAAT-------WRLKGYDATSNWVHADL-------------------L-LMGARH-------VKRVVTDRNRMTGAGVTAGLDFGLS------------- +------------------------GVTQLDLTGPAQIFSRPDTELSFAWHRIEPVLTDAGF----------------------AIVPNTTLTAA--PQADVLFVPGGQGAF-ELFEDDVALEFLRRQSTGARYVTSVCTGSFALAAA-------GLLRGKRATSHWASLGL-------------------LERFGVTPT------AQRVVHDGNVVTGAGVTSGMDFALS------------- +------------------------GLTALDMIGPWEVFLRPGWAPVAIGLDDQPIAADGGL----------------------MITPQATIADC--PPLDLLIVPGGGGVD-ALLDLPEVLDFVRGRAEAAQYVASVCTGALVLGAA-------GLLRGRRAATHWASRPL-------------------LAALGAEPS------ADRVVIDGPVATGGGVTAGIDIALA------------- +------------------------GVEILNVAGPAEVFAAEN--VVSIGINTEPVKANKGF----------------------TLVPDYSLEDC--PYLDVLVIPGGAI--EKIQSNNDVLLWLQAMSIKTNLLLSVCTGAFLLAAA-------GLLDGKTYTTHHQFIDK-------------------LSLAPYGKAI-----RLRYTDSGNIIATAGVSAGIEGALH------------- +------------------------GMTMLDAIGPYEVLRYNDAEVFFVGEKRGEIKADGFI----------------------DFNAKYSIDDI--HDADILIIPGS-PVAFKEMKNEKVLSWIRQLDKQTKWTTSVCTGSIILAAT-------GLLSGLKATSHWKIIDL-------------------L-DFDAIP-------TERVVEQGKYITAAGVSSGVDMALY------------- +------------------------GVTQLDFTAPAQALSRPGAVVAGAASSLAPIATDSGF----------------------AIVPTHDFASA--PQADILCVPGGHGVA-EALGDAATIHFIARQAARAAWVTSVCTGAFLLGRA-------GLLAGKRATTHWAYTHL-------------------LPLVGAEHQ------PGRVVEDGQIVTSGGVTSGLDFALT------------- +----------------------------------------PNTKISLVAEAMAPVLAE-GL----------------------AFLPDYPLHDS--PKFDLLFVPGGTGV-NAVMENEEILSWLKNRAKTAKYVTSVCTGSLALASA-------GLLDGYSATTHWLSLDV-------------------L-LFPRIN-V-----KDRIVRDGNRITGGGVTAGIDFALS------------- +------------------------RITQLDFTGPAQFLCRPVAKVHVAAATLDPVMTDAGF----------------------AIVPTISFDDC--PQADLLCVPGGLGVP-AALAATPLIDFVRRQGASAQWVTSVCTGAFILGRA-------GLLQGKRATTHWAYTGQ-------------------LPLVGAVYE------PARTVIDGRVITAGGVTSGIDFALT------------- +------------------------GVTQLDFTGPHQFFSRPDVEVIVASVDGQSIAA-DGL----------------------HFASLADLTQL--THCDILCVPGGSGCV-EAMQSPHYMHAVKTLAQSARYITSVCSGSLILGAA-------GLLVDKRAACHWSWRSL-------------------LSLFGAISD------SRRVVKDGNIITGGGVTAGIDFALT------------- +------------------------QVQQLDLTGPHDVFASPGVTVRLVWKTREPVASSSGL----------------------MLAPNATFDDC--PPLDVICVPGGIGVA-DLMEDADTLAFLRRHAAHARYVSSVCTGALVLGAA-------GLLRGRRATTHWAFHSL-------------------LAPFGATPV------RERVVRDGNLVTGGGVTAGIDFALT------------- +------------------------DMTHLDFTGPHQVLCRPKSETLVASRDGGAVVAEGNL----------------------VIGRTQALSTI--DRCDLLCVPGGVTAT-QWTLDDAFIKQVRRLGLQATYITSVCTGSLILGAA-------GLLQGKRAACHWAWRDL-------------------LAEFGAVID------DSRVVRDGNIITGGGVTAGIDFAFT------------- +------------------------DLTQLDFTGPLQVLNRPGATVHLVARQQGPVRTDCGP----------------------FILADTDFANC--PQLDLICVPGGWGID-QAMEDDATLDFLRRQAAGAQYVTSVCTGAFILGAA-------GLLDGVKATTHWRYHSA-------------------LPRFGAIPV------QARVVRDGSVFTGGGVTAGIDFALT------------- +------------------------GMTQLDINGPLTVLHRPNSQIYILWKNLDPVTSDEGL----------------------KILPNQTFAEC--PPLDVVCVPGGPGHL-EMIKDKEMLEFLQKQSQQAKYVTSVCTGALILGAA-------GLLQGYRATCHWAFLEQ-------------------LGYLGAQVC------RERVVIDRDRITGGGVTAGIDFGLI------------- +------------------------DMTNLDFAAPLEVFARPNTEVHILARDRSAVKTDVGS----------------------FVPPTMAIGEE--PPLNLFFVGGGPGIN-ALLGDEEILRFVAEKGLEADWVTSVCTGALVLGAA-------GLLRGYKAATHWTAMEA-------------------LRPFGAAPT------DKRVVVDRNRVTGGGVTAGIDFALT------------- +------------------------NVTQLDLTGPAQILSRGEAQVDLVWKTRDPVPTDAGF----------------------SILPTAIFAEV--PYADILCVPGGFGLN-DVIADDEAMAWVGAVGAGATWVTSVCTGSLILGAA-------GLLDGYRAGCHWAQRDM-------------------LPLFGAIPV------DARTVVDRNRVTGGGVTAGIDFALT------------- +------------------------NMTQLDLTGPFEVFSSKELQIHLVWKDMAPVRDVNGL----------------------AILPTVSMAQC--PQADILFVPGGAGQL-PLMEDEEVLTFLRGQAQTALYVTSVCTGSLILAAA-------GLLTGYRAACHWLSLNQ-------------------LAFFNVEPV------NQRVVIDGNRVTGAGVTSGIDFALS------------- +------------------------KMDQCDFTGPFEALARPNSTFMTLWKDKQPVRDMAGM----------------------QLLADTTFDEA--PQLDVLLVPGGYGQE-ALMSDEEVLGFIRRQAASARYVYSVCTGALLCGAA-------GLLQGRRATTHWTAMDA-------------------LPFFGATPS------EDRIVIDGKYVSAGGVTSGIDGSLI------------- +------------------------NLDQCDFTGPFEALSRPNSTFYTLWKDKNIVRDMQGM----------------------QLVPDTSFEDA--PQLDVLLIPGGYGQE-EAAADEEVLTFIRKQSSHALYVYSVCTGALICGAA-------GLLHGKKATTHWTAMEV-------------------LPLYGAIPS------ADRVVIDGNYVSAGGVTSGIDGSLI------------- +------------------------GLTMLDLIGPYETLRQ-HTDVHLLGSTTEEFRSD-GA----------------------PFRATEMLSDA--AYYDVVFVPGGSGT-ADAMRDPHIIDFLASRGPRARYVTSVCTGSLVLGAA-------GLLDGYRATTHWSMLDA-------------------L-FFGAIP-------SERVVIDRNRITGGGVTAGIDFGLL------------- +------------------------QLTQLDMTGPAQVLGRPGARLHFIWKRLEPVSDDLGL----------------------VFQPTATFADA--PALDMICVPGG-GCA-AMMRDEEVLSWLRQAAADARFVTSVCTGSLILAAA-------GLLEGRRSACHWSWRDR-------------------LAAFGAEPV------AERVVEDGRFLSGGGVTAGIDFAFR------------- +------------------------DMTMLDAYGPLQFLAFRGLETFTFAESSAPLPCD-GI----------------------QLMPDYSFEDC--PEIDILLVPGAGNP-LEQMQNSRVLEHLRHVGNNAQYVTSVCSGALILAEA-------GLLDGYEAATHWAYRET-------------------L-KLADVT-V-----VKRVSVDRNRITGGGVTAGIDFALS------------- +------------------------GMTQLDVTGPFEVFARPNVRMHLLWKRIEPVVSDVGL----------------------PLLPTTTFADC--PELDVFCIGGGPGQV-ATMDDDEVIAFVRDKGGSARYITSVCAGCLILGAA-------GLIDGYRSACHWLMSDQ-------------------LAAFGAIAV------DERVVVDRNRISGGGVTAGIDFGFQ------------- +------------------------GVIQLDVTGAYQVLAFPNTQVHLIWKTLDPIVSNEGL----------------------TLIPTTTLIDC--PPLDAICVPGGGGQV-EIMRDPEILNFLKQQGTTAQYVTSICTGSMILAAA-------GLLQGYKATCHWAFREQ-------------------LAMLGVEVV------PQRVQIDRNRVTGAGVTSGIDLGLT------------- +------------------------NLTLLNFTAAYEVFSRPSAKVYLLAPTLDPVYTESGF----------------------RLLPNTSFESS--PALDVLFVPGGLGVN-ARLEDAAFLHFLKTQGDRALYVTSVCTGSLLLAAA-------GLLQGYRATTHWFAMDL-------------------LELFGVEAV------TERVVIDRSRITGAGVTAALDFGLV------------- +------------------------GFTQLDLFGPADVLNRQGVEVKLLWKNLDPVIVDRGL----------------------RILPNMTFGQC--ESLDIICVPGGPGQI-ALMDDDETLNFLRRIAPGCKLVTSVCTGSLVLGAA-------GLLKGYKATSHWTSLDH-------------------LSLFGATPV------EERVVIDRNRITGAGVTSGIDFALK------------- +------------------------HLTQLDLTGPAQVLSRPGARLEYVAATLDPVPSDCGI----------------------ALVPTVTIQDA--GAADVLVVPGGDGAF-DAMLDPDVVAFVRRQAEDATWMTSVCTGAFVLGAA-------GLLAGRRATTHWASKPM-------------------LEAFGAQPV------DARIARDGAVVTAAGVSAGIDMALW------------- +------------------------MVTALDALGPAQILSAPGAQMHYIWKEKAPVASDSGY----------------------TINPTHDFDDC--PQLDVICVPGGFGQV-DIMNDEAVLGFLRTQGQDAKYVTAVCTGSLLLGAA-------GLLDGYEASCHWAWHEQ-------------------LALVGATPK------QGRVVRDRNRMTGGGVTAGIDFGLT------------- +------------------------DVTQLDFTGPIEFFENPGIELIVGSVGGRSIKSK--L----------------------TFTDLADLAKI--ERCDVLCIPGGPGF-ISAIENETFLSEIQRLGKTAKYLTSVCVGSLILAAA-------GFLEGRKAACHWAFRDM-------------------L-EFGAIA-------DARVVRDGNIITGGGVTAGIDFAQT------------- +------------------------GFTALDAVGGYEVLANPGVEVEFVSHAPGVVAADRRL----------------------GMLAHRGLDDV--TSTDVLYVPGGPGV-VAGIADARLLGWIARVQATATWTLGVCNGVALLAAA-------GVLDGVSVTTNWGWRDR-------------------V-SYGVEV-------VERVHRDGSIVTGAGVSASIDAGLF------------- +------------------------GFTLQDMVGPVTVWSMPEVEFEFVAAAKGDVMTD-GL----------------------AVRATHDFSDV--AAPDVLLVPGGGLP-VEAMQDDALLDAIAGVGAGAKWVTSVCSGSMLLGAA-------GLLQGYRSASHWSARPY-------------------L-KFGAVA-------DGRVVIDRNRASGGGITAGIDFGLV------------- +------------------------GFTLQDLAGPQTAFGL-HAKTHIIWKTMEPVPTD-GV----------------------TMNPTITIDDV--PNLDVLFVAGGGGT-PEIMKDRELLDFIARAGQTATYVTAVCTGSVLLAMA-------GLLEGYRAATYWPFYEP-------------------L-ALGIEP-------SERVCVDRNRITGGGVTAGIDFALK------------- +------------------------GLTPLDLVGPVTMLGMTWMELTVVGARIEEHET-APL----------------------RITPSHTFDQV--RDPAVLVVPGGAAP-ARAMTDKALLGYLRAASASAEITASVCSGSLLLGAA-------GLLKGKRATTHWTVLDL-------------------L-EFDATP-------VERWVEDGDVITAAGVSAGIDMGLY------------- +------------------------GMTPLDMVGPLTVLEGASTATVVVGETKDPVTT-NPL----------------------KLVATHTYEEV--PSPYALLVPGGAAP-TKALADEKLVGYLRGAAANAELVTSVCTGSLLLGQA-------GLLKGRKAATHWMFREL-------------------L-AFGAEP-------VERWVEDGNVITAAGVSAGIDLALH------------- +------------------------DVTQLDLTGPYEVLARPGASLHLLWKDRTPVRSDMGL----------------------SILPTTTLADC--PVLDLLLVPGGPGVH-ALMVDELVLDFIAGRASSVRWLVGICTGTLVLGAA-------GLLQGRRAGTHWNSRHY-------------------LPRFGAEPS------DRRVEVDGALFTGGGVTAGIDVALR------------- +------------------------GMTQLDFSAPFEVLARPGAQVDVVAESLEPVISDTGL----------------------RLLPTHTFAGG--AQPDLLFVPGGPGQN-AQMTNPAMIGYLAATGRSAAYVTSVCTGSLLLAAA-------GLLQGYKATCHWMSIDQ-------------------LGLFGVVAQ------QQRVVVDRNRITGAGVTSGMDFALT------------- +------------------------GYMPMDINGAQSVFTIGA--IYFIWKRRELVEGYIGW----------------------PTMPTMTFDEC--PDDLDVLVTGMVP--PEVIEDPEVIRFFARAGQKAKYVIGTCYGSLMLGTA-------GLLKGRRATSNSNVVPM-------------------LD-VGA-VAV-----GSDVVIDDTIYTSGPATGSFDASLL------------- +------------------------GMTFLDFIGFYDVIARKSCTTWDICGIHEEVSDEHGM----------------------MVKVTRVKPDL--KDYDMVFVPGGSG--TTLQSDDEFMNWFKG-AAGTKFKVSACTGSLLLGAA-------GFLTDKRATTHPFHYDL-------------------LPYCKE--V------VSRLVRDGHVITGGGVAASIDLGLY------------- +------------------------GMTALDLIGFTEVITRSRIRSWDYCAMTSHITDDRGL----------------------EYVIGRVKPDL--SEYELVFVPGGFT--TKLRQDSEVIAWLQT-AREAKHLVSVCTGSLLLGAA-------GLLEGKRATSNASAYDL-------------------LPYCKE--V------VARIVRDGRLITGGGVSSSIDLGFF------------- +------------------------GMTALDLIGFTEVMTRARIRSWDYCALSTQITDDRGL----------------------AYVVSRVKPDL--SEYDLVFVPGGFT--TELRYDPDVLTWLQT-AREAKHLVSVCTGSLLLGAA-------GLLEGKRATTNASAYEL-------------------LPYCKE--V------VARIVQDGRLFTGSGVSSSIDLGLY------------- +------------------------GMTSMDFTGFYEAITWGILKSWTFCSDREEVTDDRGL----------------------TMKVNEVGPDL--SKFDLVFVPGGMV--TELRNDKAFIDWIRT-AENAPYKVSVCTGALLLGAA-------GFLEGKRATTNSSAYDL-------------------LPYCEE--V------IARVVRDDRVITGGGVTASIDLGLY------------- +------------------------GQTHLDFVGFYDCMLRKAVHEMRFCSRERQVSDSGGL----------------------TIDAGEITTDL--GGFDAVFVPGGMA--TRLKDDAGFISWLAT-ARDAKYKFSVCTGSLLLGAA-------GFLRGRRATTHPLCYDL-------------------LPYCAD--M------VERLVREGEIITAGGVSSSIELGLC------------- +------------------------GMTALDFVGVYDPLTRDTMGSWDVCARTERVTA-AGL----------------------EIVPDVVDEPL--AGYDMLVVPGGFVA-RELAEDDAFVSWLSTA--DSELVVSVCTGSLLLGAA-------GFLSGKRATTHPDAYDL-------------------L-VYCDTV-------VERVVRDGDVVTAGGVTSGIDLGLE------------- +------------------------KVEELDLVGSWELIGLAEMKPKLISLNSMNPSGEHGM----------------------RFNADIHFTEN--IFPDVLIVPGGSG--ALAMEDPDVIQYLKETSSQSHSILSICTGMYLMQRA-------GLFANKKATTHWAFLDE-------------------LQ-DTSVEV------IERYIKDGNIWSSAGVSAGMDMTLA------------- +------------------------GVEPIDLAAL-GVVSMRRL-YLTVAAAPGLQTLANGL----------------------RVAADTGFDDC--PPVDWLIVPGGPG--WAAAEDPALLDFLRARAAT--PMVSLCTGAMILAAA-------GLLDGRVATTKCQPLDL-------------------LERHPRVEA------RALLVDEGQLITGGGVGLCIDTLLY------------- +------------------------GVEPIDLATI-GVLSMRRI-FWTVAAAAGPVRLANGL----------------------TVIADYGFDEL--PPINTLIVTGGPG--WQCCADQAALTFLQKMAGRA-TLASVCTGAMILAAA-------GLLEGQVATTKVEPLEI-------------------MSQYPGIDV------KALLTDNGSIITGGGVSRCIDATLY------------- +------------------------DVEELDFVGPWEMLTMSKLACLIVAEKREPVICAKGL----------------------SINPHVSFADC--PPLDYLLVPGGMG--TREVDNPAMVQFLAAQAPRCKALLSVCTGAFVLHAA-------GLLSGKTATTHWGSLDR-------------------LA-LGDVNVV-----EQRFVQDGDVWTSAGVSAGTDLMLA------------- +------------------------EVEELDFVGPWEMLTMSKLACLIVAEKREPVVCAKGL----------------------SINPHVSFADC--RPLDHLLVPGGMG--TREVGNPAMTRFLADQAPGCQTLMSVCTGAFVLHAA-------GLLSGKTATTHWGSLDR-------------------LA-LGDVKVV-----EQRFVQDGNVWTSAGVSAGTDLMLA------------- +------------------------QVEELDFVGPFEVLSYNKLRVLTVAETINPVQAFNGL----------------------KVIPDIDFANC--PPLDIIVVPGGKGR-MKAMHDPAIRDFILQQAKTARYITSVCTGAFILAEA-------GILDGKRATTYFAALPE-------------------L-GYPAIH-P-----VSKVVQDGSVITAAGVSSGLELGFY------------- +------------------------QVEELDFVGPFEVLSYNK--VILVAETIEPIRAFNGM----------------------RILPDVTLTDC--PSLDIILTPGGKG--RAAMKSVAIKHFIQEQMKTVKYVASVCTGAFLLAEA-------GLLTGKKATTYHTTFRE-------------------LSYSV---QV-----VSKVVQDGNIITSGGVSSGLELGFY------------- +------------------------GVEELDFVGPWEVFTMAQI-VFTVGWPQAAIRCAKGL----------------------YVVADHAFSDA--PMADVVVVPGGKG--TPLSEDTTFIDALRTYLAAAKWQTSVCTGAALLGKA-------GFLDGKHATTNRSAFEF-------------------FAAAPNALLV-----ELRYVRDGTVLTGAGVSAGLDMALW------------- +------------------------HVAELDCVGPHSVFALNIIDVVLISEMTDPITGIGGM----------------------KITPDATFDDH--PDLDVLLLPGTAD--VHALKNKRALPWIKAQAEKVTFLTAVCTGGLILQKA-------GLLKGKKATTHWMETDL-------------------ME-DPDTTVI-----PVRYVRDGNIVTSQGVSAGIDMALW------------- +------------------------GAEELDFTGPWEVFTASMLRVLLIAEHPDPVRCNKGM----------------------RVLPDHTLDDH--PALDVLLVPGGNGT-RREVSNPVLIDWIRNTSAGTAWTTSVCTGALLLHEA-------GPARGRRVATHHLFEDT-------------------L-ARGDVTVV-----RARYVVDGKLVTSQGVSAGIDMALW------------- +------------------------GLNIMDLTGPSEVFGSRIPT---IASSQDTIASSEGI----------------------ILKLLATKSDGSLSRYEILVMPGAPPGNVKAIEDENLLAVLRTSGGRHRWILSVCTGAAFLGTI-------GALSGKTATCHWSYLDT-------------------LEICRAETNV-----VKRWVDTVRIITAGGVSCGIDAALW------------- +------------------------RLDTLDFAGPLEALSEIYPSVF-----EPTVTAGTEL----------------------VTSRHIPLEDAYLADFDVLVIPGGSSNVVEA---SEPLNLIRADEGRVRTLLSVCTGSLFLAQV-------GALKGLVATTHPYYFEK-------------------FTLCGGQTTI-----VERYVVNLRVITSGGVSCGLDACMW------------- +------------------------GGDLLDYTGPLEVFNSYTRPTTTFARTSPIKAAATGT----------------------MTVPDSTLSDLKLEEFDVLVIPGAGPKIIDLIASREIMDLIKHPRDAHRVLLSVCTGALILGAA-------GVLRGKQATTHHMFYDM-------------------LEVSAKVEVL-----KKRWVDAVNIVTTGGVSSGLDGSLY------------- +------------------------DIEVLDFCGPFEVLSVRLDEVKLVAMTKDVIFTKGNM----------------------KIIPDFDFKTC--PKLDILIVPGGMG--TKLMYDERVLDFISKKANEVELLTSVCTGSLILASA-------KLLDGVNATTHWKSLQR-------------------MDEFKNVKVC-----KKHYVEDGNIISSAGISAGIDMALY------------- +------------------------DVEVLDFCGPFEVFSVGK--VYTVAE-HTPISARNSL----------------------SVNPTYTLDTC--PQPDILVVPGGGGRHVKEMHNETLLAWINQRYPQSEHVLSVCTGALILAKA-------SLVENMAATTHHGALDE-------------------LQIAPTAEVK-----AARVVDSGKLIFSGGISAGIDAAFY------------- +------------------------DVEVLDFAGPFEVLSVTYPDVRTVSEHGTMITARNGL----------------------KVIPDFSFSNA--PHFDIVIVPGGLG--ARELHNPHMIKWIQDRMQTVDFMTSVCTGALLLAEA-------GLLEGKRATTHWASYDW-------------------LDKYPAVEVV-----RVKYVADGSIVSSGGISAGIHMAFY------------- +------------------------DVEVLDFCGPFEVFSVRPPGVVTLAATPEVVRARYGL----------------------RVVPDHTLDDH--PPLDLVVIPGGRG--TRERRNGALLRWLKQQHARAELTASVCTGAFLLAEC-------GLLDGRRATTHWGSVQA-------------------MDRYPQVAVA-----EARFVDEGRVLTAAGISAGIDLALY------------- +------------------------GVELLDFTGPYEALSARLDAPQLVAASLEPVACANGP----------------------RFLPDTTFADC--TAPHILLVPGGWG--VKPLDDTALLAWIRKIGAKARTVAGVCTGSMLLGKA-------GLLEGRRATTHWRSLDW-------------------MASYPGVTVV-----DAHVVEDGHVLTSAGISAGIDLGLH------------- +------------------------QVEVLDFAGPFEVFATRLDEIRLIAEHKRPITTTGGM----------------------MVLPHHDFTDC--PELDILVVPGGKG--AREINNPVLMNWIRERSDGLSLLAGVCTGAMLLGKA-------GLLDGLRATTHWRSLDW-------------------MDSFPEVMVV-----EEFVVDAGSVITSAGISAGIDMALQ------------- +------------------------QVEVLDFAGPFEVFSTRLDEIRLIAEHKQVVTTTGGM----------------------MVVPHHDFEDC--PDLDILVVPGGRG--AREISNIRLMEWLRQQSDGLSLLAGVCTGSMLLGQA-------GLLEGLRATTHWRSLDW-------------------MEYFPDVMVV-----EEFVVDAGSVITSAGISAGIDMALQ------------- +------------------------NVQPMDVIGPWEVFATKTILMFLVAESSNEVCCANQI----------------------SLKPHCEFNNS--PQFDYLLVPGGAG--REQVNNPRLISFLKKQAQNTDYLLSVCTGAFLLHAA-------GLLIHHEATTYWRAMPE-------------------LS-FEDVQLV-----EKRIVKSGKVWTTGGISSGIDLAFE------------- +------------------------GLTQLDLTGPWEVLTRPNTVCHLLSNDLAPVRSAGGL----------------------SILPTLTYAEC--GRLDIAVVPGGASN-LDAMENDRLLSFLRDIEPDCQFMTAVCTGTLVLAAA-------GLLEGYECTTHWSALHR-------------------L-AYGARP-------IRRVVFDRERVTGGGVTAGIDFGPE------------- +------------------------DFTTLDLIGAQQTLSMPNARIECVAAEAGPVMTD-GV----------------------ALIADKSFKTA--SSPDIILVPGGRAS-SDVLEDSTMVDFVARQGADATWVCSVCSGALLLGMA-------GLLEGYRAASHWSVIDT-------------------L-AFGAIP-------TQRVVIDRNRATGGGVTAGVDFGLT------------- +------------------------DMTLLDLVGPLQVIKNERFGVVTVGERLDPVPT-VGL----------------------GAQPERTFAQV--PAPFGLVVPGGLAG-PKAIANDGLMAYVRAAGRTAEVLGSVCTGSIILAAA-------GLLEGRSATTHWTFLEH-------------------L-RLGAVP-------VKRWVEDGNVITAAGVSAGIDMALA------------- +------------------------GMTALDAVAPQLVFANLNTRVHLVWKTLEPVVTDTGL----------------------ALLPTATFETC--PALDVLFVGGAKATW-PLLADVETVEFVRSRGSAARWVTSVCTGSLLLGAA-------GLLQGYRATSHWAVRD--------------------CGDFGATPV------DARVVIDGNRMTGGGVTAGMDFGLQ------------- +------------------------GFTTLDLVGPQQVLSAPDTTVHLVAKTADPVTTDSGI----------------------TIAPDRSFADC--EQYDLLFIPGGRGTE-IMVRDDATLAFVRTIATNARYLTSVCTGSLILAAA-------GLLDGYRAASHWAFRE--------------------FAAYGAIPD------DRRVVVDRDRMTGGGVTAGIDFALQ------------- +------------------------GGSLTSITGPIEILTIARLAINIVTQDNQDAVGLGGV----------------------RLKPNKLIGEI--KQTDIILVGS-IGVPYFDFCTQETLDWLQMMEEKNIPIVSVCTGSFVLAKA-------NLLNNRKATTHWLFTNL-------------------FDMFPQVQLH-----SIKVTSDNNIFCTSGTYEYNDVMMH------------- +------------------------NMTALDFVGPFEVLGSPVVT-RFVAASLEPVKS-NGL----------------------VVVPTDTFSAV--KSTDIIVVPGSGHW-RLLKDSGGVVEWLREVHPTTKWTTSVCTGSTLLAEA-------GLVS--KATTHWAARSD-------------------L-DRGVEV-------SDRVVFDGKVVTGAGVSAGIDMALR------------- +------------------------KFTALDGIGPYEVLQRPDIDITFIAAERGVVRSEGML----------------------GIEADGTFDDF--PTPDIVVFPGGHGTR-ALLTDEQVLDWVRSVHPTTTYTTSVCTGSLVLAAA-------GLLEGLTATTHWGARDV-------------------L-QHGSTP-------VDRVVEHRRIITAAGVSSGIDMALR------------- +------------------------GFMPLDVVGPYDVLRFPDHEVVFVASDPGVINGAGGF----------------------GLQAQATPADI--DTCDILLVPGGRGTRD-HAARKDLTDWIARIHQTTTWTTSVCTGSLLLGAA-------GILTDTDATTHWNAIPA-------------------LS-FGAHY-------TERVVRRGKVVTAAGVSSGIDMALT------------- +------------------------GMTALDAIGPYEVLNRPGVTVQRASLNSGPVHA-SGL----------------------TLMAEHALADI--SKTDVLLIPGGGTAT-ALREYPEILEWIRKIHEHTLWTTSVCTGSLILGAA-------GLLSGVKATTHWAVMNR-------------------LH-WGALP-------T-NRFVVGKIVTAAGVSAGIDMAFY------------- +------------------------NMTALDLVGPYEVLSAPSATGHFVAATREPVRADGL-----------------------TVQPTTTFAEL--TRPGIVVVPGGSGWRN-ALEARDLIGWLAAVHPTTSWTTSVCTGSTLLAKA-------GVLAGRTATTHWACRDV-------------------LG-LGVEV-------SDRVVFDGDVVSAAGVSAGIDMALR------------- +------------------------GFTALDVIGPYEVLGRPGTQVVFVAENPGLVTNDGSL----------------------SINVVKHVDEV--PGPDVVLVGGGPGQAD--MTDGALHDWLRMVDRSATWMTSVCTGSLVLAAS-------GVLSGRRATTHWGALDQ-------------------L-QFGVTP-T------ERVVIDGHYATGAGVSAGIDMALT------------- +------------------------RFTALDIVGPFQTLVDPGFDVFFIADEVGPVEDHGRL----------------------TMSATKKFDEI--DELDVVVVPGGMADSS-IGDDDPVVQFVRRIHATTIWTTSVCTGSIFLAHA-------GILDGLEATTHWASYDR-------------------LE-LGAIP-------T-KRVVQGKIMTAAGVSAGIDMGLV------------- +------------------------GMTALDAIGPYEILRGPGAVVQFVARQRGPVTVDTFL----------------------RLQADLSCDEV--TRADILVVPGGNAP-A-QMRNPDTLAWLRCLYPTTRWTLSVCTGSLILAAA-------GILTGGEAATHWSARET-------------------LQ-FGITP-------SARVVRRGNILTAAGVSAGIDAALT------------- +------------------------GVTALDAIGPYEAFAGMKCKIKFVAKEKGLIQLDKMG----------------------YLHAEYCYAEV--PSMDVLIVPGGI--GCELMNDEETLNWIRQLHKTSKWTTSVCSGSMVLGAA-------GLLEGVPATSHWFVCES-------------------L-ALGAIP-------QERVVHHGKIVTAAGVSSGIDMALQ------------- +------------------------GFNALNLVGPHEVLSRDAR-CYLVSEKAGKVLSEKGI----------------------AVEADVGFLDC--PSIDTFVVTGGLGQ-MDMMSHPGLMTFLRNQGSHSRFVAAVCTGALLLAAA-------GLLQGRYATTHWLAREE-------------------L-KYGAIP-------NERVVWDGKFVTGAGVSPGIDLALD------------- +------------------------GFTALDATGPFDVFSRPGGQVTFVSSAGGLVRADSAL----------------------EIGT-RPLSAA--PRPDVVVVPGGTFTNR-HLGDEQLLGWLRTAHASATWTTSVCTGALLLGAA-------GLLDGRRATTHWYELES-------------------LV-FGAEP-------V-ERVVRGDVVTAAGVSAGIDMALW------------- +------------------------GITALDAIGPYEVFAAQQCHVKFVAKDKGMIKLDKMG----------------------YLHADYSFSDI--TSADILVVPGCSPPNYNPMNDEVTLNWIRNIHQTTKWTTSVCNGSLILSAA-------GLLKGMKATSHWGSFDI-------------------L-SLGTIP-------TERVVRQDKMVTAAGVSSGIDMALQ------------- +------------------------GFTALDAIGPYEVLHRPGVRVEFVSETAGLYLADGHL----------------------RVEAPVCFEQV--PSPDVLVVPGGLVKNL-PLTNKAFLDYIVKVHKTSLYTTSVCTGALLLGAA-------GILHGLKGTTHWAAFDN-------------------LS-YGVTP-------VQRYIRQGKIIMSAGVSAGIDSNLE------------- +------------------------GVTPLDVAGPYDVLARPGASVVLVGAEKALYRDESSF----------------------AVEATATFDEI--TKPDVVVVPGGPPEAVGPACQGPIPAWLRAVHPSTRWTTSVCTGALLLGAA-------GLLVGREATTHWAGVGV-------------------LQ-MGATP-------VERIVTHERLMLAAGVSSGIDMALA------------- +------------------------GFTALDAIGPYEVLVSPDTDVYFVADQQGPIYADGQL----------------------ALVATATWDEL--PHPTVVVIPGGAGTMQ-ALAHQPLLNWLQTAAPTVEWMTSVCTGVFVLGAA-------GLLHGLQVTSHWTSREF-------------------IQYCAATY-------TERFIQQGNIITAAGVSAGIDMALF------------- +------------------------GFTALDAIGPYEMVCRPGARTVFVADRPRPVLADGEV----------------------TLGATHAYEDV--AAPDLLLVPGGPGQSA--MTDPALLGWLRAADARTRWTTSVCTGALLLAAA-------GLLTGRRATTHWLFPDV-------------------L-EYGAEP-V------ERVVRDGKYVTAAGVSAGIDMGLA------------- +------------------------GLTLIDLVGPLQAFSFPGFETQIVWQKKGPIRSD-GV----------------------TIEATHDFEDC--WNPDILFVPGNTKA-LAQLEDKKTIDFIADRGQRAQWVTSVCNGSLLLAAA-------GLLRGYKAASYWFTREH-------------------L-LFGATP-------TARWVIDRNRATGGGMTAGVDFGLA------------- +------------------------GFTALDVVGPYQVLAFPGVRVRFVGEQVGPVVDDRSL----------------------TLHTSARLSDV--TDPDAVVVPGGPGTE--QALNGPIPLWLKDVHEQTTWTTSVCSGALLLAAA-------GLLDGQDATSHYSVLDV-------------------LM-FGARP-------TRRVVELQHVITAAGVSSGIDMALR------------- +------------------------GMTALDAIGPYEVLRFPDTEIRFVGHEVGPVVTDGVL----------------------ALGVTHTFAET--PAPQIVVVPGGPAATA-VAADTAVLDWLRAAHRTAEWTTSVCTGALVLAAA-------GLLDGKPATTHWAAQSA-------------------LL-LGAQP-------RQERVVRARIVTAAGVSAGIDMALW------------- +------------------------GLTPLDAIGPFDVLGKPRARVRTVGIERGNVHSRVSL----------------------TLHADNALTEV--NAPDVVVVPGGAGADE-LAHDPMIRAWLRKVVPTSRAVLSVSTGSLILAGA-------GVLEGREATTHWRALDL-------------------LG-FGVRT-------K-ERIVTGTITTAATAAAGLDASFL------------- +------------------------GFTALDAVGPYEALCRPGVRVVTVGRKAGPVRTDGQL----------------------ALGAERAMTDV--PHADVLLIPGGGNRGTATMNDPSVLAWVRRIHQHSTWTTSVCTGALVLGSA-------GLLRGVPATTYWASRPY-------------------LETFGAVV-------T-GRFVEGKIITAAGVSAGIDLGLH------------- +------------------------GYSLLDPTGPAEVLSRPGASVTMIAERRGPVRTDGDV----------------------AVLAERALDEA--GRLDVLLVPGAGNRGTAAMRNRTLLDWIRETNRRTRYTTSVCTGSLILAAA-------GLLDGRRATTYWASAPY-------------------MKTFDITY-------V-ERYVKGKFITSAGVSAGLDMALY------------- +------------------------GFSLLDPTGPAEVLSRPGAEVVMIGERTGPVRCDGQA----------------------ALIADVTVDDM--RDMDVLIVPGGSDEAVAVFDNDRLRDWIVRVHKRTRFTTSVCTGAAILGHL-------GLLKGRRATTYWAGAEF-------------------L-SVGATY-------VERYVRDGKIITSAGVSAGQDMAYY------------- +------------------------GVDLLDVAVPHELFDWAQIEVHLISFDGPSVATRDRL----------------------TLGGD--LPSFRVEQVDLLWVPGGDPVALRLMLDSARMDFLSRQASSADYAASVCEGALLAAAA-------GYLDGCKATTHWAFLPC-------------------L-LFPRIDVA-----PPRYIVDGTRITGGGISSGLDEALM------------- +------------------------GTTMLDWIGPYELLHRPGIELVLAAKTRDLYKSDGMV----------------------SYQANVLLQEI--DKADVLLIPGGGMG-VAVSNDAQVMDWIKRIDKTSRITASVCTGALILGRA-------GLLRGRRATTHWALQNM-------------------L-DQGATY-------MERWVVSDKYWTSAGVSAGLDMTLA------------- +------------------------GVDMLDVAGPFEMFDWDFDVEIVAAKPGMKRFRNRGF----------------------PFEVAKSFAEC--TQYDAVWIPGGDPDALEIINDHTYVQFLTRQAAGAKYMCSVCEGAMLFAAS-------GLLDDHWATTHWAFLEC-------------------FTLFPKVKVA-----DPRFVLDRNRLTGGGISAGLDEALM------------- +------------------------GIDLLDVMGPYEMFSWDKS-TLILSACGDMVTSGNGV----------------------RFHAHASFRET--PKLDIVWVPGGVETALEMLQDSHYFTYLRKVSAHAKWVCSVCEGAMLLART-------GLLDRHRATTRWAFVRC-------------------L-EFRKIEVD-----TQRFVVSGNRLTGGGISAGLDEALK------------- +------------------------GVDLLDVTVPYEVFNWQTRDVYLVGQSGAAVKTRDGF----------------------TIIPECSFEQFEGITCNLIWVPGGDPANLAQMKNACYTNFIIGLSKNADYVTSVCEGALLLANA-------GLLTHYKATTHWAFIPC-------------------L-SYPGIYVQ-----EVRFVVDGNRVTGGGVSSGLDECFE------------- +------------------------DVDLFDVTGAHEVFKWSDPA-LIAASVEQPIVTRDGF----------------------RFLATHNFQQV--AALDVLWVPGGDLRALEMMSGHEYMSFLATIGARAKWVCSVCEGALLSAAA-------GLLDGYEATTHWKFIPC-------------------L-QFEKVTVV-----DPRYHLDRNRLTGGGISSAIDESLH------------- +------------------------GADLLDIAGPHEVFAFDGAVVATVGQTKAPTRTAGVL----------------------KIVPQYDFTDC--PPIDLLFVPGGGD-GLDAIGDQALLDFLVTRAAHASYVTSVCTGGLILASA-------GLLDGYLATTHWAFVEG-------------------L-RFPKVTIA-----NPRWIKDRDRITGGGISSTIDESLF------------- +------------------------GVNELDLMGPRYILGQMG--IDLIALKKGNIRTVMGT----------------------EIVPNTTIDSV--SQLDILVIPGGFK--GLATYDTKLHDWIRKIDKNTTYTAAVCTGGWILGAT-------GLLKDKKATSNWYQAEQ-------------------MTKYG--AKF-----EKRFVNDGKYWTSAGVTAGMDMSLA------------- +------------------------GVNSLDVFGPRYVLCQMG--MKLIALKSGNVKTVTGI----------------------EFVPDTTIDKV--DSLDVLVIPGGFR--GEASYNKDVQEWIRKIDLTSTYTTSVCTGGWILGSS-------GLLRGKKATTNWFNAEE-------------------MTKYG--AEF-----TERFSKDGKYWTSAGVTAGMDMSLA------------- +-------------------------FEDIELVVPVMELLYRGAEVIIGHFEAEPGLLGETITGNF--GVTIPFQEIPD-----SFYTYKPLNDVRMSDFDVLVITGAFN-PWNMVMTGQ-ADWLQEANTAGKILSAICHGPIPLAEA-------GLVSGRHLTGWEASRD-------------------SVEIMGGSFDCN----EAAALVDGRIVTGRTPAEIPEFIDAI------------ +MASKRALVILAK------------GAEEMETVIPVDVMRRAGIKVTIAGLAGKDVQCSRDVV----------------------ICPDTSLEDAKEGPYDVVILPGGNLGAQNLSESAAVKEILKEQEKRKGLIAAICAGPTALLAH-------EIGFGSKVTTHPLAKDKM--------------------MNGSHYSYS----ESRVERDGLILTSRGPGTSFEFALAIVEA--------- +--MPKIIIPIS------------NGFEEIEAISIIDICRRANIEVIIASVENIKTIGAHNI----------------------KIEADCKIEDVKADGFDMIVLPGGLPNAFTLAEDINVQNLLKEFKEKEKKLQPYVLHLMLYIKL------------------------------------------------------------------------------------------------ +--MVKVAVMLA------------QGFEEIEALTVVDVLRRANITCDMVGFEE-QVTGSHAI----------------------QVRADRVFDG-DLSDYDMLVLPGGMPGSAHLRDNQALVQELQSFEQEGKN-------------------------------------------------------------------------------------------------------------- +--MPKVLVPFA------------EGMEEMEAVIIVDVLRRAGVEVTSASLQKGPVRASRGV----------------------CLLADTTLDSIDLKNFDMIVLPGGSGGTKVLEADPKIAAFLQEAKKETNGSAPS--APRLVF-------------------------------------------------------------------------------------------------- +--MVRTAVIFA------------NGCEEIEGLSIVDILRRLNIECDMIGLDSLDITGGHNI----------------------RFKCDKLISN-DLLNYDMVALPGGMGGTQLLASNIDLQNIMKKKICK----------------------------------------------------------------------------------------------------------------- +--MPKVLVPFA------------EGMEEMEAVIIVDVLRRAGIEVLSASLKEGPVKASRGI----------------------RILADTTLDEINFEDFDMIVLPGGGGGTKVLNAEPKVSELLKNAKEKTNGSPRS--AQLLVF-------------------------------------------------------------------------------------------------- +--MPKVLVPFA------------EGMEEMEAVIIVDVLRRAEIEVVSASLIEGPVKASRGV----------------------RILADTTLDEVNFENFDMIVLPGGGGGTKVLGSEPKILELLKNAKEKTNGSRQF--VPLLVF-------------------------------------------------------------------------------------------------- +--MKKALVLLF------------DKFEEIEAIAPIDIMRRAGVDVLTASLESLCVVGRSGI----------------------TVEADAFFKDVCRRNFDIVVLPGGPGVHNLKGCEPVL-EVLKKQAESGGLLKPKAAGCWRLFAP------------------------------------------------------------------------------------------------ +--MKNVLLPIA------------RGFEEIELVSVADILRRAGVRVVVASLDSKRVLGAHHI----------------------VIEADSALPELEMEHFNAIVLAGGYNGMQNLANNELIKLWLTTFKQEQKLIAAICASPIVLDKA------------------------------------------------------------------------------------------------ +--MPAVLIPLA------------EGCEELEAVTLIDLLRRADFTVVTASLTKQQVTASRGV----------------------RLVADVWLEDVMHDDFDMIVLPGGLPGATYLNDDHRIHAILKRLNKSGKAIAAICAAPLVLAHA------------------------------------------------------------------------------------------------ +------------------------GFEKSELFQPLETLKNEGATVHIISNKDGAIKDDT-------------N-------WGKTINVDKTLNHANESDYNALVLPGGQINPDVLRIEDSALNFVKAFFKSGKPVAAICHAPC----------------------------------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------------------------------------------------------------------AKDWTYQGYRMTIFSDPEEAVFES--LEGARIRYYPAPAMATAGGDMQY-AKAWQPHVVVDRELITGQNPFSDKALAEALLTL--------- +-------------------------------------------------------------------------------------------------------------------------------------------------------AAGWPYAGYRMTVFSTGEEQQLEPS-GLGGNVQFYPVNALAEAGAHVDT-VANWHSNVVVDRELITGQQPMSAPEFGDVLVAK--------- +-------------------------------------------------------------------------------------------------------------------------------------------------------TGEWIYKNYRMTVISNQEEEQAKL--LKGEEMKFYPQTALQSLGAKYQN-TTAWTPNVVVDRELITGQNPASAVLVGKTLLEK--------- +------------------------GSEEMEVLVTVDVLRRAKADVVVASAEEVVVA-----RHG----------------T--RIVADALLQDAAGQQFDLIVVPGGMGVKTTLADKVELMALLKEHAAAGRAYGAIGAATAQVLEP------HGLIGGSKATTCASRADR-------------------------PSEC-----GSRVVVDGNLATSGSTGTAMEFALAVVEK--------- +------------------------GSEEMEIIILVDILRRAKINVVLASVEKSILG-----SQR----------------M--KIVADKSITSASDSIYDLIVLPGGPGAER-LHRSRILKKLLNLQMQAGRMYGGVCSAL-KVLQQ------QGLLEDKTVTAHHAVATC-------------------------QVID-----QPKVVIDGNLITGKGLGTVVDFALAIIRK--------- +------------------------GSEEMEALNLIDVLRRAGANVTIASVEDKIVR-----RHK----------------F--NLIADMLLDEATKMRFDLIVMPGGLGAQK-FSSTKKLVDLLKKQADLNKPYGAICASPAHVLEP------HGLLKGKKATAFPPMSTD-------------------------QSAC-----EHRVVVDGNIITSRAPGTATEFALAIVEK--------- +------------------------GSEEIEALNLIDVLRRAGANVTVASVEDTIVR-----RHK----------------F--NLIADMMLDEAAKMEFDLIVMPGGLGAQK-FACTDKLVDLLKKQAGSGKPYGAICASPAHVLEP------HGLLKGKKATAFPPMATD-------------------------QSLC-----ENRVVIDGNLITSRAPGTATEFALAIVEK--------- +------------------------GIEEMEAIIIVDALRRANADVVVASAEDGVTA-----RHG----------------T--RIVADVMLDEAARAPFDLII--GGMGAKT-LGGCEQLVALLKKQAEANRPYGAIGAATAHVLEP------HGLLKGKKATTCASMAAD-------------------------DSEC-----ENRVVVDGNVITSRSPGTAMEYAVAVVE---------- +------------------------GSEEMEAITIIDALHRANASVVVASVEDGIAA-----LHG----------------M--RIVADVMLDDAAQTQFDLIIVPGGMGAET-LGGSAKLVTLLKKQAEAKRPYGAIGAATAHVLQP------HGLLTGRKATTCTSMTAD-------------------------ASEC-----ENRVVVDGNVITSRGAGTAME----------------- +----PVLMVVADQS----------DFYYQEYGDTRMSIEAAGLDVQVAATTTNPTV-PHVNTGE---GAD-----------GGLLTPDLALADVNASDYSAIVFVGGWGSMYQYAFKGVVNELINDFVEQDKYVTAICHGTTVLAWAR--VDGVSLLAGRTVAI-PYIGSPTFYQGQYY-GYFELSQQAQMDFNGAITQGSSDTAADDVWVDGKIITAENYDSAAMFGQVIAS---------- +--------------------------------------------------------------------------------------------------------------MTDLFYDKHLPLLLSSFQYRGKTIGLICHAPALLTTLPSGPKGGFLFQGYRVNSVTKTEEWFIETF-VMKGSPVRNISALLKERGMVYESSFLPGSGYATRDRNLITSQNPFSGKEFTKLYLDA--------- +----------------------GPGAEEMEFVIAADVLRRGGIQVTVAGLPDAVVKCSRDVN----------------------IKPDIGVSEA-KGPYDVLVLPGGLGGSKAMAESEAVGELLKEQEKAGRWIAAICAAPTALKAH-------HVAEGKTITCYPAMRAQ--------------------MEEGGKYKYK----EDKVIVDGNVITSRGPGTAFDFALVI------------ +-------------------------------------------------------------------------------------------------------------------------ALVGKFAAEGKVVASIDQGHLVLAAS-------GLLKGKRCASGVPMRVI-------------------SNLAGAAAVVP-----EGAVADGKLVTAASWPDLAEF---------------- +-------------------------------------------------------------------------------------------------------------------------------MEAKKPVASICHGQQILAAA-------GVLKGKKCTAYPAAKLD-------------------VVLASATWLEP-----DRCFTDGNLVTGAAWPGHPEF---------------- +-------------------------------------------------------------------------------------------------------------------------------MDKGKPVASICHGQQILSAA-------GVLKGKKCTAYPAVKLN-------------------VVLGGATWLEP-----NRCFTDGNLVTGAAWPGHPEF---------------- +-------------------------------------------------------------------------------------------------------------------------SIVKQFEEKKKLIASICHGQQILAAA-------DVLKGKRCTAYPAVKLN-------------------VLLSGGGWLEP-----ETCFRDGNLVTAAAWPAHPQF---------------- +MASKRALVILAK------------GAEEMETVIPVDVMRRAGIKVIVAGLAGKDVQCSRDVV----------------------ICPDTSLEEAKQGPYDVVVLPGGNLGAQNLSESPAVREILKEQESRKGLIAAICAGPTALLAH-------EIGFGSKVTTHPLAKDKM------M--------------TGSHYSYS----ESRVERDGQVLTSRGPGTSFEFALAIVEA--------- +---------------------------DYEFNVPFRALQALGCKVDAVTPSKKKGETCVTAIHD--DEGAQAFSEKRGHN----LVITANWSDVSVYDYDCLVVPGGRSP-ELLVMNDKAVTLVKEFAERNRVIAGVGQGQWLLAAA-------GVLKGKRCASGDGMK--------V-----------MVKMGGGELEE-----SKGCVSDGKLVTAVGWPALPY----------------- +----RILMILIPD-RDVSPSEHGAELRLERFVIPYYVFVDAGIDLVLASPGGGAPWIRSQANAAS-PLPQLQRY-QADRAVHDAVNDTLALDDVHAEDFGGAFCIGLPGPLWLEDSADPAARMIARFLDAGKPVAVIPS-------------------------------------------------------------------------------------------------------- +----RIAVM-------LSRSSEAGNVGLEQFLGVYYALQDAGAEVLVASMCGGYPWPTRTRLGAE-ADELARRF-QADRRARDDLANTLRFGELFEEDFHGGFCVGEPGALWRDADRNSAAALIAQFLQAGKPIALLPS-------------------------------------------------------------------------------------------------------- +----RILMVLVPD-RDLP-----GHLRLERFIAPYYTFLEAGAEVIVASPEGGFVFDRLSSLEDV-PVALGERF-KADARLHEVITDTLAIGQVFPEDFDAAFCVGVVGRLWEAAAAAAAAPLLARFLSAGKAVATIPS-------------------------------------------------------------------------------------------------------- +----RFLIILAAD-G------DNSEVRIARLAPAYYLFKDAPAEVVLATPSGGFADLTSLRQTVH-KEPTVGRF-LTDRAARDDLADTLRLDQIVTEDFDAAFCIGLSGPLWSAE---GVAATIRAFLTSGKPVAVIPG-------------------------------------------------------------------------------------------------------- +----RFLIIIAVE-DS--DGISNSGVWIPKIAPPYYLFKEVPAEVALATPSGGFAALL--GQTSD-REPFVRRF-LSDREARDDLADTLSLGQIVADDFDAAFCVGFSGSVWGTHS-RGPGPLIKTFLEDGKPVAIIPG-------------------------------------------------------------------------------------------------------- +----RLLVILSAD-MV--RESPNDEIRIERIAHVYYMFKDLEADVVLATPTGGYAALASLRQCPS-EEPCVQRF-LSDREARDDLADTLSLDQIVIDDFDAAFCFGFSGSIWEADE-LGVAPVIRAFLADQKPVAIIPG-------------------------------------------------------------------------------------------------------- +----RFLVILSTD-ES--GDVSASAVTLGRIAPPYYLFKDHGAEVVLATLTGGYPRLPD-RETEP-HEKSLRRF-FLDRAARDDLADTLAADQIVAEDFDAALCLGFSGALWGNHN-NSVATILTTLLETGKPVAVIPG-------------------------------------------------------------------------------------------------------- +----RFLILIV-E-GD--EGAGNPEVDLARIAIPYYAFRTFGSEVVMATSEGGPPMLVDMRSADV-SDEAIRRF-KGDRNARDELADSLGLDQIVVEDFAAAFCIGLSGRIWTDDD-RGVAALVRGFLGVGKPVALVPG-------------------------------------------------------------------------------------------------------- +----RFLILIV-E-GE--DGAANPEVDLARIATPYYAFKNFGSEVVMATLLGGPPLVVDMRDAEM-VEESVRRF-KGDRDAREELADTLALDQIVVDDFAAAFCIGLSGRIWTDAN-DGVAALVRTFLGTGRPVALVPG-------------------------------------------------------------------------------------------------------- +----------------------------------------------------------------------QTYTEKPGHRF--TL--NASFDDIDPGGYDALAIAGERA-PEYLRLNDRVLELVRHFAQAKKPVAAICHAAQLLAAA-------GVIEGRRISAYPVCTP------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------------------------------------RDTTAAGQTTALVCHGPIALLSTLPDAAPKWIYTGYRMTVISNAEEEQAKAL-LGGGAMKFYPQTALQRAGGIYSSNEVPFTAHMVTDRELITGENPASALDVADEML----------- +------------------------GMCEVTAVMALHALKTA-VEAELV----V-----IGT-DGT------------------VYRA-LP----HWAETDALLVSG--G-IHD-G-------TLPRRVGTKLVVGGVSAGAVIVGAA-------GLLNGRPATSHHP-AF-------------------EPLAK------YAEVDARIVDVG--ITAGGGPLAAFDLPL-------------- +------------------------GVEELDGVEKLQVFGPF-ARAHPVTVKPV-----ETY-SFG------------------TRVA-AA----AWRDAALIVVPG--G-FGR-G-------VWAEF------------------------------ERLPSAPRHLARS-------------------HLAER------GARVDQRVVDDG--VTAGGVVSSGIDGAL-------------- +------------------------GFGELVALAPFEVLKRGGFQVELVASEP-KSE-VITS-YGI------------------QLAVHDHLRIGN--KPDVLIVPGGGDQGRKEAERGELPRLIRELHAAGTVVAGVCTGGMLLAEA-------GVLKQKQAAMHYLAKD-------------------ELKRYDADVLD-----YRIVD-HGDVITARGVTSGVDLAL-------------- +------------------------GFDALDVVAPWEMFARAGLEVGVVRVDG-PAL-VTAA-DGL------------------QLQVDDELGT-----PDALFVPGGSNNGRREIRQGTLPRIIAELSTEVRWVASVCTGALLLGEA-------GILRDRNATTNPAALE-------------------ELSRYDAIVRQ-----NRVVD-DGNVVSAGAVTSGLDLAL-------------- +------------------------GFDELDALVPWGWLNRH-AE--LAAPAPR-----ISM-HGL------------------TVDAQQP----LANAADAVLFGG--G-TTR-G-------VLLDR--VRQRIAGVGAGTLLLARL-------GLLGDAAVATDAASKP-------------------WVVAA------GVRADTAFEAHG--ATACGGLAAERVAA--------------- +------------------------GVDEMDVMGPFEVWGNARLELTLVGLDG-PVE-VTGM-NGL------------------QFRATDGLGKT---HPDAVCVPGGGEKGWAEVQRGVLPARLAELAPDLSWIGSVCTGSMLLAAA-------GLTKDRAATTHHTAWA-------------------DLQETGANLKA-----HRVVD-DGDLITAGGITSGIDLAF-------------- +------------------------GVEEQDFIAPVEVLGLAALTTTLVSTAK-PGT-VTCM-HGT------------------RVEVPNGWSPP---DADVLIVPGGGGPGHRLIADKGFLARLAAS---KALPVGICTGVMVLSAA-------GLTRGRPATTHAGAKA-------------------DLAAQGATLVN-----ARVVD-DGTLITGGGITSGLEVAL-------------- +------------------------GVEEQDFVAPVEVLGLA-VVTSLVSAGRP-----VKC-T-Y------------------DTVVEV-PRTW-S-P-DILVVPGGGG-GVH-NADQ---GFLRRL--SRALPVGICTGTMVLSAA-------GLTKGRNATTHNGAKA-------------------DLAAQ------GAKIDARVV-DD-GLITGGGITAGLEVSL-------------- +------------------------GFGELVSFASFEVLKRAPFTVELVSSVQ-KQE-VTTS-FGV------------------TVKLHDFLRMDN--RPDLLIVPGGGEHGRKEAELGTLTKIIREMHNEGTIVAGVCTGGMLLATS-------GILNDKKATMHHLAQS-------------------EMSEYGAEFLP-----YRIVD-QGNVITARGVTSGLDLAL-------------- +------------------------GFDELDAVGPYEVFDYAPGRVRYVTLDE-RDR-VTAS-HGT------------------RVGVDGVLPEPDGEAPDLLVVPGGGEASWAEAQKGDVPRALGEYHAAGVRTAAVCTGAMLLAAA-------GVTGGRRAVTHASAID-------------------ELRESGATVVD-----ARVVD-DGDLLTAGGVTSGIDLAL-------------- +-------------------------MLSSGLSLPIEMWKAAKSPFRLCRPENI-----LGI-NSE------------------PILTHSGFSITADRHYDVIYLPA--L-RNP-------RAVVRQQAARGTRIAAVGTGCCFLAES-------GLLNGKPATTHWHYFK-------------------QFSRD------YPSQTKHFLTQA--IFCAASVKALSDLTI-------------- +------------------------EVSELDAFGPFGVLAAAAMNLYTVARSRM-----LTA-GGL------------------VVTPHWAFMSA-P-A-DVLLVPG--G-AVD-KRDRAVMGYLGEH--NVRFLLGIGSGAFLLGEL-------GLVRDQRATAWAGALE-------------------RLRDY------EAGASGVAK-NA-GRWFVGGGASALAGGL-------------- +------------------------GVEELDAVGPYEVFGTAVCNVYL-GETMD-----TCI-LNM------------------KLPPHYTFEDA-P-KPDILIIPG--G-GTR-QHNEKLIEWVNKTAEGCEMVASVCSGARITLTS-------GIAKGKRITTHWGVV---------------------LRER------GEAEDVRFVRD--GYISSQGISAGIDMSL-------------- +------------------------GVAELDFVGPKDVFFASEDTLYT-APSKD-----TCF-GGL------------------KVLPDHDFETA-P-APDILVVPG--T-DTS-VENRALLEWVERASRHCIWTTGVCTGTAILIAA-------GPAKGKTVTSHWSAI---------------------LRAL------NEAEGMRYVAD--GVVTSAGVSAGIDMAL-------------- +------------------------NAEELDFVGPWEVFTASADTAVL-AENAG-----RCA-KGM------------------RVLPDHPLDDH-P-PLDVLLVPG--G-GAR-PHNPVVTEWIAKTSARAAWTVAVCTGTFLLHAA-------GPARGRRVTTHRSFV---------------------LAAL------GGTPDARYVVD--GLVTSQGVSAGIDSAL-------------- +------------------------GVDELDAIAPYEILRSA-EVV-LCALDAP-----IEG-A-H------------------GLRIEVRDAIP-S-T-DWVIVPGGGQ-GVR-IAQTKLARELQRL--TGASVASVCTGAMLLSAA-------GFLRGRPCTTHQVARD-------------------ALEKN------GGVVDARVV-DD-GVITAGGVTSGIDLAL-------------- +------------------------DVEPIDIGATFGVLSMA--DMILVANKAG-----RLS-NGL------------------EIIAPYSVTNC-P-A-DVLMILG--G-AWP-SKDEQTLDFIRTF--KG-IVASVCTGALILAGA-------GLLDGKGATTRRFAPT-------------------GMKKL------YPGTEARFV-DS-GVVTGGGVVLAVDTTL-------------- +------------------------GFDPLDVIAPYEVLSAGAVSVELVSAEGPREV-VSGT-GGL------------------ALRATAALDPG---RPGLIVIPGAAPAGAPRTLTTELPALLRAMENPDVTVSAVCGGSLVLAMA-------GLLEGRCATTHHMGLD-------------------MLDATGAHAVS-----ARVVD-DGDLVTGAGVTSGLDLGL-------------- +------------------------GFDPLDVIAPYEVLFAGALSVELVSAEGPREV-PSGS-GLL------------------ALRATARLDPQ---RADLVLIPGAVPLPAPRSITTGLPALLKALDRPDSIVATVCGGSMVLAMA-------GLIEGRHATTNRLGLD-------------------LLDATGVVAID-----ARIVD-DGDLVSGAGVTSGLDLGL-------------- +------------------------GHDVLDYAGPYEVFANIVFDITLIADDSV-----ISS-RNL------------------CVNRHLSIEDAYTVDYDILIIPG--G-VRT-RNGPE-VKFLRAYQRRERVILSVCTGALLLGCT-------QLLRGRRATTHHKALD-------------------VLRHVCYNEE-ATGIKARYVDGGGTIVTSGGISSGIDASL-------------- +------------------------LVEVLDFAGPYEVFACALFRVHT-AA-AG-----ACR-GGL------------------KVRPDYSLEKA-P-GLDLIIVPG--G-GAR-RKQKPVIDFLRERAQSPAHIASACTGSFLLAAA-------GLLDGLEATTHGARL---------------------LAKA------FPRKAQKIV-DQ-GVITAGGVSSGIDLAL-------------- +------------------------QVEALDLNGPIDVFAKARFELYS-SPNEN-----YEG-NIL------------------QIKATYNFSNA-P-Q-DIIVIPG--A-PSLGDSNIEIAEWIKSQHKAAALIFSVCTGSVILAAT-------GILDNKKATTHFGAMQ-------------------YLKMH------ESIENVRYV-LD-DVLTTAGITSGLDGTL-------------- +------------------------QVEVLDLNGPLDVFVKASYHCYT-GKTKE-----YEA-NTM------------------AIIPTYDLQTC-P-K-DMIVVPG--A-PEHQDFQETVLKWVKNQHDSGTVVFTVCTGCMLLSKT-------GILNGHNITTHSMLLD-------------------ALEQH------NPERGVRYV-DE-GLITTAGITAGIDAAL-------------- +------------------------SVVQFDVMGAYQVLTFP--LW----KTRA-----TSN-EGL------------------ILTPTTTLTDC-R-P-DVICLPGG-G-GQL-MKDDETLDFLKQQ--NAKYITSICTGSMILAAG-------GLIQGYKSACHWAFRE-------------------QLAMF------GVEVPQPVV-ID-RRITVAGVTSSIDFGL-------------- +------------------------QFDGDELLGLLEALKST------LSKSGR-----EGM-KKE------------------RFTPHGTIIDW-NGKYPAIVLTG--G-GAA------IVPQI---HRAGSTIAALGTSIVVVAKA-------GLLPGRAACPADAA-A-------------------QSEL--EN---LGICEEIPVLAD--IVTAQGCSSIQPMVE-------------- +------------------------YYCEEELEIPYEILKEE------ASGKMK-----DGM-KTG------------------RRMPDRLIVDTMEGIFHGVVVVG--G-GAR------ITRLL---YKSGFVVTAIGQGIGCLAEA-------SLVENLEVAVDESKAK-------------------KPFLILEK---GKALSNEEVIVH--IVTGRDAASAEPFAR-------------- +------------------------GTFNTELTAPFDIFQHTPMNTFT-AQSKN-----TTF-EGL------------------RLQPDYDFNDA-P-R-DILVIPS--A-HHL-LENTEVINWIKQTGSAATYITSHCDGAFMLAQA-------GLLDHVVSTTFPSDVH-------------------KMRER------FPNENVWFV-HD-GVITSAGGARSFEAAM-------------- +------------------------GFNEMDSMIAFTMLNRLGLVAEIVSTHS---N-VVSM-NGL------------------RIQANPTLERLE--EYDGVIFGSSK-----YAENSTFISSF-QLDPDRQYIGAQCSGALLLIAK-------GIIGSDVSISTDKTES-------------------LASATGLSFSS-----SSFSS-KGNIATAGGCLAAEYLAS-------------- +------------------------NFTDIDVFLPWDLLNRVDWNVQLLGTEK---T-HISM-SGL------------------RIPMTGSISDIP--TADAVIFASGK-----LYKNQEYINSI-HVDPQRQLIGSMCSGSLLLGAK-------KLLTGKKATTYPSVVE-------------------QLKEFDVDVIE-----QSFVN-EGSISTAAGCFAAQDLSA-------------- +------------------------RFTDIDVFLPWDLLNRVEWQVQIAATTS---H-ITSV-AGL------------------TIPTHADLTALS--DADAVLIASGA-----LLKESELLEAVRNLNPDTQLLASMCSGSLLLASA-------GHLTGKRATSYYTREK-------------------QLRSYGVEFVS-----EPFVLAGPQIATAAGCMASLDLCH-------------- +------------------------GFTDVDLFLPWDLFNRVPWSVRICADTP---Q-VTSN-TGI------------------AITPHGGLGELA--QADAVFIVSGP-----KLRDPDFMRQL-ELDPRRQVIGAIDSGVLFLARL-------GLLDGLSATTYPGVFA-------------------ELEAMGVKTEH-----RPLVV-HGQIATAGGCLATQDLAG-------------- +------------------------RFTDIDLFLAWDLFARIPCSVQIAAKTP---R-ITSS-TGL------------------TIDCHAGLAAAS--EADAVYFCSGP-----LVDDAEACDIL-RLDPSRQVLAAVDSGAIVLGKL-------GHLRGLRATTYPDLHD-------------------RLHAYGATLVR-----SSLVV-EGNVATAAQCLAGVELVR-------------- +------------------------DFTDIDFFLIKDILGRTDWVVKVLGTKP---S-HHSV-LGN------------------TVTTDDHLMAAN--DADAVTFCSGQ-----VLADPQFMSSF-KLDPAKQLIGSICAGSFILAKL-------GLLDGKQATTHPDAKP-------------------ALLTLGVDVQD-----KPLVV-EGNIATAGGCLSSIYLTG-------------- +------------------------EFTDIDLFLMWDLFNRVDWEVRIIGEKS---H-HISA-TGL------------------ITATHGLIEEAN--QSDVVLFVSGR-----KMQDKPWLSRF-NLNSERQMIGSVCSGALLLAAL-------GLLAGKTATTYPTTKQ-------------------LLEGFGIEVEE-----KPFIE-HGNIATSGGCLAAQYVVG-------------- +------------------------GLFDTGLTVMPDALGAADFEVSI------------GM-RKR------------------V-QSSHGLLIPVQPRPDWVIVPA--L-TTS------RADLREAKHEAGAKIGASCIGTFLLAET-------GLPDGRQVTTNWPLAP-------------------LFRQR------YPDDESRMPIPS--GVTAGSAMGHLDLAP-------------- +------------------------DAEIVDFTAPHGVFSVA-LEVFLIADAQR-----QAQ-AGF------------------TVLPNYSFADR-P-AMDAFLIPG--G-GTR-TWNGRLHEFINAL-PARCLLTSVCTGSWIYGRM-------GLLDGIPATNRKEPDR-------------------VLAEI------APASHARVVDA--GIVTAGGIASGMELGF-------------- +------------------------DAEIVDFAAPYGVFSVA-LDAFFISDSSR-----QAQ-GGF------------------TILPNYSFSDN-P-SIDAFLIPG--G-GTR-IYNTRLHDYINSL-PESTILTSVCTGSWIYGHM-------GLLDGIAATNRKEPDK-------------------LLAKI------APSSRSRVVDS--GIVTGGGIAAGMEVGF-------------- +------------------------GVEPVDL-ATYGVLSMA--EICTIAPKRG-----LFS-NGL------------------VVQADFGIEDA-P-E-DVLIVTG--G-GWV-AKNQTTLLYLKHA--TS-LIASVCTGAMILAAS-------GVLDGKTATTKRAVVE-------------------PMQKN------YDSVEGSVI-DN-GVITGGGVTLCIDTTL-------------- +------------------------QIEPIELAV-IGTLSMAELQYVT-SEHGG-----VLN-NGL------------------RVDTDYSFADA-P-AADVLIVTG--G-GWQ-ANNPNMLDFLVRRHASGECLASVCTGAMLLASA-------GLLAGKRATTKVPVAG-------------------KMAEN------YDDIAALVVDE--GIITGGGVTLGIDLTL-------------- +------------------------GFELLDVFGPAEIFSKV-LQVEFASADGE-----ASS-QGV------------------KILPDTTFD---SLVCDTVIVPG--G-GTR-VKDADFLARIHKMASCTSLVCSICTGSAVLAAA-------GLLEGYAATSNKLAFD-------------------WATSF------GKDSSARWVHD--RRWTSSGVAAGIDMAV-------------- +------------------------DVELLDFAGPYEVFTTAPFVTHTLAQQ-P-----R-ARAGL------------------TIRADTDLSQA---PLDLLIVPGGV----DAQKNADLMHWLAQAARQTRCVASVCTGVFLLAQA-------GVLDHRPVTTHWEDFE-------------------ALHQQ------FPARDVRFID--HGLATSAGISAGIDLAL-------------- +------------------------YAEPIDFTGPYEVFATAQFLPYLISESGD-----T-ARHGY------------------QVVPHRSIHNH-P-ELDVLIVSGGV----AEMKNMRAINWIQEQASKVKIVASVCNGVFLLAQA-------KLLSDRRVTAHEQHLD-------------------DLAQQ------FPDKNTRWVE--DGIITSAGMSAGIDMSL-------------- +------------------------GAECLDFCGPFEVFNTAPINVSFVAPSHV-----T-SRGGM------------------SVNPHYSIYSH-P-KFDLLIVVGGL----HICGDHNVLNWLAETANHTSQCASVCTGVFLYAEA-------GLIDGKRVTTHWQDID-------------------DLREQ------YPSEDVRFVM--DQFTSSAGISAGIDMSL-------------- +------------------------NVEVLDFCGPFDVFCTAHINVSLVAPTHS-----KTR-GGL------------------SVNPNYSIHGH-P-KFDLLIVAG--G-YTE-INNPTVLRWLAETARHTPKCASVCTGVFIFAQA-------GIIDGKQVTTHWASIQ-------------------DLQDQ------FPQKEQRFTID-N-FISSAGITSGIDMSL-------------- +------------------------DAEVLDFAGPFEVFSVTLFNVFTISSSKE-----KAV-NGL------------------SVNPDYDFTHH-P-QIDILIISG--G-GTRLIKNREILNWIFPIIENAEYTLSICSGARILGEL-------GLLDNKPYCTHHEVYD-------------------HMKEI------APTPELRYIQT-E-IFTSGGISAGIDLSF-------------- +------------------------NAEVLDFAGPFEVFSVALFNVFTVARDSN-----SAV-NGL------------------SVNPKYNFQDC-P-PVDILIISG--G-GSRAMVDQETLTWVEQIHHNTLYTVSICSGSRILGTL-------GLLDNKKYCTHQDVYE-------------------HMEEI------VPSKEKRFVQE-G-IFTSGGISAGIDLSF-------------- +------------------------GVEVMDFAGPYEVFTATYFDVFTVNEQRR-----RTS-NGL------------------IVKADYDFSNC-P-PADVLVIPG--G-VRPLISNGTVLKWIESQNQNTEITFSVCNGAMLLAKA-------GLLKGLSATTHHYFYD-------------------KLSEI------DSTQKIRYVDT-G-IVTSAGISAGIDAAL-------------- +------------------------NAEVLNFSGPFEVFASARIHVFLIGETNL-----E-ARGGF------------------CVTPKYDIHTH-P-ELDLLVVVGGV----TEMQKTHIIQLIQEQGHNVPIMASVCTGAFLLAQA-------GLLNSYQATTHWNDIE-------------------EFRQT------YPDENVRWVD--NQVITSGGIPAGIDMSL-------------- +------------------------GMEILDFAGPVEVFTNA-WEVFI-AWDKS-----TSQ-GIV------------------KILPQYDITDC-P-PADILATFG--G-SEE-VQQAEVIRWIQETAPACQVLFSVCTGVFYYATA-------GLLNGHRVTTFHGEI---------------------LKQE------APQTGVKYV-DS-GIVTAAGVSSGIDGAL-------------- +------------------------DVEALDLAGPYEVFTTALFDVRCVARTTA-----R-ARAGL------------------RIVPDGDFSDA-V-LPDVLIVPGGV----DAMRCPDTLAWIARAAASARVTASVCTGAFLLAAA-------GVVRDGAVTTHWEDVD-------------------DLRRQ------FPRTGVRWVQHGAGLFTSAGISAGIDLSL-------------- +------------------------NVEILDFAGPMEVFTIAGAPYRALLSQTQ-----RTS-HGR------------------GCVIEFSQEGQ-D-DWDVVVIPG--G-GTR-MENLHLLDWISRFRGKRKTILSVCTGTLLLAKA-------AILDGMKVTTHYSARE-------------------T----------GGGVEDRVV-AEGVVVTSGGVSSGIDGAL-------------- +-------------------------MEVLDYAGPYEVFNVAPFSVFS-GLTTS-----VGR-GGF------------------TVQPTYSLDDA-P-PADLLVVPG--G-GTR-LRDERLLAWLRERAGEVELLLSVCTGALLLGAA-------GLLEHRSATTHHDAF---------------------LAAL------SPTRGQRFVRSS-EVVTSAGVSAGVDASL-------------- +------------------------GADELDVVGPYAVLRSW-PEVVTVSADGR-----VLA-RGL------------------KVVPDRSAADV-T-D-HVVIQPG--G-GVR-LRDRDHVAWLRET--RTAVLAGVGSGTLVLAAA-------GALAGRPVAASRAWSD-------------------DLVRI------EPSTEGRLV-DD-GVLTAAGGASSTAAGL-------------- +------------------------QVEELDAVGPWEVLAYWGWSITT-SADGG-----TGA-KGL------------------TLGSHHSYADL-S-DLDVLIHPG--G-GTS-LEDQDHLTWVRTQAANVPLMTSVCTGSLVYAAA-------GLLINRPATTHWASL---------------------LSEL------DPTVNARYVDD--GMITSAGVSAGIDMAL-------------- +------------------------GAEELDVVGPWEVLGFWPVRLVT-AREEG-----RCA-KGL------------------RLGVDHSPADA-P-ALDVLIHPG--G-GTR-KDDGAHLEWLRELHRREVLLASVCTGSLVLAAA-------GLLRDRPATTHRDFT---------------------LAAL------DGTAAERYVDD--GIVTSAGVSAGIDMAF-------------- +------------------------SFDPMDLIGPYEIFSWGAFENFITSGEPN-----IAH-SKL------------------SINIDLTLEEAYEAEFDILLIPG--G-SQN-----EPISLIKTFDGGVRTLMSVCTGSLFLAES-------GVLAGKSATTHPLYTE-------------------KLKTILEPQG-GKVHEERFVANPGLIVTGGGISAGMDAAL-------------- +------------------------GVTQLDFTGPYEVFSRI--KIFL-AQSKD-----QSE-SGM------------------KLIPDFDFSDC-P-DLDILLVPG--G-GIT-MEEFTVLDFLKRKTVNSKFITSVCTGSLLLASA-------GLLDGYKATTHWLSL---------------------LKLF------PVQSGERFVKD--RRITGGGVTAGIDFAL-------------- +-------------------------MEVLDFAGPFEVFSVALLTLQV-VTDER-----RAK-NGL------------------TIVADTSLAAV-F-ETDMLIIPG--G-GSK-LENTEAMQDISRLNGHAKLTWSVCSGARILAAL-------GVLDRQPFTTHHLVI---------------------VQKL------TKNVDKRFVKT--GYATAAGVSAGIDLAL-------------- +------------------------GIELLDFSGPFEVFSACLFSINT-ADSKL-----KTA-NGL------------------KVMADFDFLDC-P-QPDILVVPG--G-GAR-MQHSATLDFVASTTEKAEFCLSICTGALILACA-------GLLENQKATTFHGAF---------------------LASV------APRPGVRFVDN--GIITSAGIAAGMDATL-------------- +------------------------DVEVLDFAGPFEVFSVTPFQVTTISESGH-----TAR-NGL------------------KVIPDYSIHTA-P-TYDLLVIPG--G-GTREIHNKVLLDWIRKHSEEVQWMTSVCTGALLLAEA-------GLLDGKRATTHWASLD-------------------SMRS-------YPKEGVKFVDED--IVTSGGISAGIHMAF-------------- +------------------------GMTALDLIGFYDPITRMELEWDFC-SYTK-----VDD-KGL------------------PFFPEKVAESL-N-S-DLIFVPG--G-GSR-QFDSGFISWLRTA--PVKLKVSVCTGALLLGSA-------GFLRGKKATTHPSAFE-------------------ELETY------CCEIDKRVV-DE-GIITGRGVSSSIDLGL-------------- +------------------------GVVLLEFAGPLQVFDVAPFQPVV-SRSGA-----RTR-EGV------------------GIQAQASLQDH-P-PLDLVIVAG--G--LQ-LAAPEVAAWLRQVAGSSEVTGSVCVGSFLLGRA-------GLLDQREATTHFEDT---------------------LRAI------APAADRLWI-DE-GIVTSGGFAAGIDMAL-------------- +------------------------YVDALDFAGPYEVFTMSPFQVFTVSKEGE-----TAH-NGL------------------KVIPDYSFKNC-P-AFDVLLVPG--GIKAMVMEDQQIIGWIGAQPH--ALIASVCTGSFFLGKA-------GLLDGKDATTNQSALS-------------------LFGRT------FEKTGRRYIDT-G-VVTSAGITAGISMTL-------------- +------------------------KVDLLDIAGAFDVFAVSDFKVYTVGDNQR-----NTV-SGL------------------TIQPKYSLENC-P-LPDILIVPG--G-GSREMNNATTTHWINQTAARAEIVLSVCTGALLLAKA-------NLLDGLRVTTNRNAFD-------------------LLREI------APPEDVRYVDN-G-IVMSAGVTAGFDAAL-------------- +------------------------KMFASTVMQAKDFFHLAAFETRL-SPDGQ-----NSF-SDV------------------TLPVDG---AL-C-Q-DIIVIPA--F-DDF-QRYPQVLPWLREQHANGAVICGEATGVYWLAEA-------GLLDGKEATTYWRFFS-------------------AFAER------YPNQDKHLT-DA-DVYCAGGTTSACDLYI-------------- +------------------------GVDAFDFVGPAEIFSLVPFDIKYVSENGA-----TAS-NNL------------------IIQPDFSMDDA-P-SFDILIVPG--GIKPIVMGSKKTIQWIINHSHEAQLVASVCTGALLLASA-------GILNGKKATTNRAALD-------------------FMEQK------FPERDSKFVDQ-G-VITAQGPAAGLNLAF-------------- +------------------------GVQLLDVAGPVDALTSADYQVVI-SADGK-----TTS-AGV------------------RIAADTTFDEV-P-AIGTMIVPG--R-DWQ-VSDRALVDAVRTLAQRSKRVAGVCAGAFPLAES-------GLLDGRRAATHWQLA---------------------LERR------YPKPDPLFVRD--GIVTSAGITAGIDLTV-------------- +----------------------------------MDMFSEARYQTVL-AADRN-----RAS-NGI------------------QMLADLFEEAM-G-G-DIILVAG--T-APP-ELDPRLLQWIRELSWRSSLYGSICTGAFVLGSA-------GLLDDRRVTTHWQDAQ-------------------ALAAR------FPRPDLIYV-RD-GLITAADVTAGIDLGL-------------- +------------------------GFETLDYFGPMEMLGGA-IEIITVAQGRE-----PSV-HGQ------------------RIVVDKTIA---ENDYDLLFIPG--G-SAL-AKDQALMQWIREASANAERVMAVCTGTVLLGMT-------GVLDGRKATTNKIDFN-------------------DTVPL------APNKEARWVED--GFFTSSGVSAGMDMSL-------------- +------------------------GFETLDIFGPVEMLGAS-FQVKFYSTDGG----VRSY-QSV------------------PVLTEPLDT---AA-PEVLIVPG--G-GVY-LEDEAFIARLAQLADQAQYVLSVCNGAFLYAQA-------GVLDGHRATTFKARMD-------------------KAEDL------FPNRTARWTVD--GLYVSSGVSAGTDMAL-------------- +------------------------EFEPLDVFGPFEVFFNT-VRNRLFCLDGP----VCGA-GHV------------------PVSAVGPNE---IH-RGILLIPG--G-GTR-SKDRRWLDRLGELASEASQVLTVCTGSALLAAT-------GLLDGRRATSNDLAFD-------------------WVTSV------SDRRDARWTVD--GFRTSSGISAGIDMAL-------------- +------------------------EFEPLDVFGPFEVFFNT-VRTRLFCLDGP----VSGA-GHV------------------PVFAVGPNE---IH-RGVLLIPG--G-GTR-SKDRRWLDRLGELASEASQVLTVCTGSALLAAT-------GLLDGHRATSNDLAFD-------------------WVTSV------SDRRDARWTVD--GFRTSSGISAGIDMAL-------------- +------------------------GFELLDFYGPLEMFGLA-FVVYQVAEKMG-----RSS-AGV------------------CGYAEYALA---DRRYDLILVPG--G-GTR-ASNPALLEWLRRQAHSARILASVCTGAGVLAAA-------GLLDGYRATTNKQSFA-------------------WPMSQ------GLEKQARWVED--RRYTSAGISAGMDMAL-------------- +------------------------GFATLDIAGPLQFFEQL-IETILIAREAGT--------GGC------------------SIVASYSFA---SPALDVLLVPG--G-GCR-FHDAAYQDFIKHHSSRAQYVLSVCTGSGFLAAC-------GLLDGKSATTNKVAFR-------------------EIQLG------DGRKHARWVVD--GVWTSSGVTAGMDMVC-------------- +------------------------GVVQQDFVGVTSYLEQLQVKFLTIALAAG-----RS-RFGM------------------PLYATHGFED--VEHIDVLVVPG--G-PRF-QKNEPFIKFLKGAAETATHVLTVCTGSAILATT-------GLLDGKRATTNKMAYQ-------------------GVTEA------HPTHKARWVQD--GIWTSSGVTAGMDMAH-------------- +------------------------DFETLDIMGPVELFGLL--QVQFYSLNGG------SK-HGV------------------CIQTK-SFSEM-HNDQSILLVPG--G-VTF-IKNQQFLDQLKTLAAQSRHVLTICTGSSLLAAT-------DLLNGIKATSNKMAFE-------------------FVQKL------NDQAQARWVIDG--FYTSSGVSAGMDMTL-------------- +------------------------GVDPLDLIGPMQPLGFLGEQLIA-ETDG----------GPL------------------RLTPSHTFAEV-P-APDVLVVPG--A-TPL-MSDRVLTDYVRSAAEHAQIVASVCSGSLLLAAA-------GLLDGRKATTHWTAF---------------------LAEL------GVHVRARWVED--GFVTAAGQSAGIDMGL-------------- +------------------------GFEMLDAYGPMELWGNLAVEVVTIAARQG-----ASA-QGP------------------KTVADYGFD---NPALDYLLVPG--G-AVF-LKDRATLDWLKAQAMQTPLVMSVCNGASFLAAA-------GILDNRPATTNKMFWK-------------------MSTDP------GPKKKARWVDD--GVVTASGVSAGMDMSL-------------- +------------------------NVEELDFVAPFEVLSYISTKVIL-APSLE-----QAF-NGL------------------KILPDASFESA-P-ALDILLFPG--G-GRI-MKKPSMKDFIQAHQSEATYLTSVCTGAFFLAEA-------GLLLGKEATTYHSAF---------------------LAAY------GVNVSSKVVHD--GIITAAGVSSGLELGF-------------- +------------------------NVEELDFVAPFEVLSYISTNVLL-APNLE-----QAF-NGL------------------KILPDASFESA-P-ALDILLFPG--G-GRI-MKKPSMRTFIEAHQSKTTYLTSVCTGAFFLAEA-------GLLLGKEVTTYHSAF---------------------LAAY------GVNVSSKVVHD--GIITAAGVSSGLELGF-------------- +------------------------GMELQDFAGPTDVFVKAVYEIFT-SFTQE-----RER-NAV------------------AITADYDFNNL-P-E-DLIIVPG--A-MDVTK----IQAFLNTKKEVGITIASICTGAFFLAEA-------GLLENIKYTTHFLRAD-------------------LLQSE------LNNKDVRFV-DS-GILTGSGITSGIDLAL-------------- +------------------------GAEEQDVVGPYEMFFWMDFAVDFIAPTIN-----VMS-SGM------------------QWTPDFSYDNA-P-A-NMIVAPG--G-GAH-RHKDGTIDYIKRVAPGSKYVMSVCTGAFLLGAA-------GLLDGRHCQVSSHNYD-------------------RFERE------VPKPSLSFV-QE-GLFTSNGPCSGHATAL-------------- +------------------------RFQLLDAFGPLQMFSLL-YTLQTISQTGI-----TSQ-QQI------------------QIEPQFSFN---DFQSDILIIPG--G-GLQ-IHDPLTLFWLKRFAPKQTLICSVCTGAALLATA-------GLLNYRRATTNKKQFH-------------------WVQKL------GHNSSARWVRD--SIFTASGGSSGIDMAL-------------- +------------------------GFDLLQVSAAISLFHSL-FEILLISENGE-----ASQ-QQV------------------VLNADLSYQ---AMAYDILYVPG--G-GIE-TGSEPVVSWLAKQCRHDTLVCSSCLGAALLAQA-------GLLENHTATTNKQHFN-------------------WVTQF------GKQPVARWTQD--KIFTSSGNTACLDMFI-------------- +------------------------QFDLLQVSSVLSVFSLY-FTIQLISEHGQ-----TSQ-QGY------------------TLSVDQSCY---TSELSVLYIPG--G-GVE-AMNPRLCEWIEKQHQPEHYLCASCTGTALLANA-------GVLTSKSATTNKRLYR-------------------WVTGF------GDEPVARWVQD--GIFTASGGIACLDMSL-------------- +------------------------GVTALDYQGPIELLKFVSIDVTYLSHNLE-----EP-AAGP------------------LILPDASYDTTGSTQYDIILVPGG---HAAQNVADPIVLFLKGQAPGAKYIMSVCTGSWFLAKA-------GILNGKKATTNKAAFT-------------------LIME-------TSDKKARWTVDDNNLWTSSGVTAGQDMAN-------------- +----------------------------MISTGPMEILEAAKFECEFVAESRD-----RG-SSGP------------------FIVATKTFDEVEGKQFDIILVPAG---SFDESIPKGVAKFIRAQVPGTKYVLSR---------------------------------------------------------------TSPAKARWVVDG--FWTSSGVTAGQDMAY-------------- +------------------------NNALLDIQGTMELLETAKFESEYIAETRE-----RG-VAGP------------------PIVATKTLDEVASKQFDIILIPGG----VKEEMPQSVVEFVRAQVPGAQYVLTVCTGSWLLASL-------GLLDGKRATSNKFFFN-------------------EIKK-------TSPARSRWVVDG--IWTASGVSAGQDMAY-------------- +------------------------GVMQLDFIGPTAYLEVLPVTFHTISHVQG-----NERS-FM------------------PLFASKGYRD--ATRFDILLIPG--A-HCY-AKDPGFKEYIRTVAERSTHVLTVCTGSGVLAQT-------GLLDGKNATTNKVEFD-------------------VIARS------YPNRKARWAVD--GIWTSSGVAAGMDMAH-------------- +------------------------EMTVLDYQGPIEILGGFAIDVEYLSHSDE-----TP-FVGP------------------RVLPTGTYEGAMKKQFDILLIPGG---SASTHVHPSLLEFVKQQAPGAKHILTVCTGSWILAGT-------GLLEGKRATTNKMLYR-------------------LVTE-------TKDPKARYVIGDDHIWTASGVTAGMDLAN-------------- +------------------------GVQLLDFSGPLDLLGFLLFSLTQLSTEDT-----SA-SCGL------------------VIKPGSTYARE-LTQYDVLLVPGG---GSSGKTPEVLIKFLQAQAPRVRYLLSVCSGSWILQQA-------GLLKGKRATTNKSLFN-------------------IITA-------SKDHKARWVEDG--VWTASGVAAGMDMTI-------------- +------------------------ETTLTDFIPPCEILASARFRFEFIAPSMR-----TAFRFGP------------------TINPTKTYQQAMKIQYDVIWVPAG---LPNPRTPQDELEFIRFQAPGAKYIVSVCTGAAILAEA-------GLLSGKRATTNKMFFR-------------------VVEA-------MSPPVARWIVDG--IWTSSGVIAGTDMTL-------------- +------------------------GFHALDVFGPLDILNLLPLNLYLLSSSLEATM-KPSSTFGE------------------AIVPSHTFSA--PPELDVLLVPG--G-GTR-ANTAPAMDFIKEVFPRLKYLITVCTGSALVART-------GLLDGKRATTNKRAWG-------------------WATSQ------GPAPKARWVVD--GVWTSSGISAGIDAAY-------------- +------------------------DVTSLDYQGPIALFGCIMLEIVYLAESLD-----KS-SPGP------------------LVVPSRRYDEIGDEQFDILLIPGG---VARENVPRSLLEFVQRQALGACTFQPF------ARVP-------GFLQERV----------------------------SSVD-------TRGAKARWVVNEGRIWTSSGVTAGK------------------ +------------------------GGMLFESAGIADILMQACYQVKL-TTQPH-----IGQ-SGL------------------NLLADHRLHEIDPEP-DTIMITG--R-QNP--EGMAVVDWLRLAAPHARRIVSICGGAMLLAQT-------GLLDGRRATTHWKLLE-------------------TMQAE------FPQGGPLYI-QD-EIWTSGGVSSGFDLTL-------------- +------------------------GALLLNAAGPLEVFAAAPYRIVL-SPLGG-----ETI-SGI------------------AVTTRSAQVEA-L-E-DTLIVIG--G-GVA-ETDHDVKAWLQRRAPAARRLCSIGTGAFALAAA-------GLLDGQRVVTHWKFAE-------------------ELQGR------YPTREALYL-HD-GLWTSGGASAGIDLGL-------------- +------------------------GIQALDVVGPFEVFAGAGYDVTL-SPDGQ-----TTA-TGL------------------ALMTQPL-PDP-S-AVDTVLLPG--G-GVD-RGNIELMDWIKAVAGTARRLVTVCTGAFLAAQA-------GLLDGRRATTHWAFA---------------------LARE------FPARDPIFIRS--SLWTAAGVTAGIDLAL-------------- +------------------------GIQALDVVGPFEVFAGAGYDVTL-SPDGQ-----TTA-TGL------------------ALMTQ-LPDPS-A-P-DTVLLPG--G-RCR-ARQHRAHGLDQSGRGHRAPPGHVCHGRIPAAQA-------GLLDGRRATTHWAFAD-------------------RLAAS------FPPATPS-S-SAAPRWTAAGVTAGIDLAL-------------- +-------------------------------MGPFEVFAAAGYQPVLACIDG----------QPV------------------ATPMGLTFATARLPDPHQ---PS--T----PRGAGEPAAHRLDPARRQRLH------WRLPGRA-------GRAARRLHRHHPLGLR-------------------RPAPARVP---V---DHRRPRADLGGVDRRRVTAGIDLAL-------------- +------------------------GVLLMDVAGPAQVFASTAYDIAI-SEDGG-----ATD-TGL------------------TLCADVSFATV-A-RADVFIVPG--G-GID-LDDPLLQRFLKRVAPHMERFVSICSGSLLTASA-------GLLNGRKATTHWERV---------------------ARER------FPSLDEIFTHD--GFHCSAGVTTGIDLAL-------------- +------------------------GVIPFELGIPSRIFGAALYEVLT-TVDGN-----RTE-ADF------------------GVSVDHGPELL-A-T-DTVVIPA--T-ELG-GTLPSSVAAALSHVRSGTRHVSICIASYVLAAA-------GLLDGRRATTHWKHAD-------------------HFQRT------FPQPNVLYV-DE-GVLTSAGVAAGLDLCL-------------- +------------------------GVQLLDVSAPLDVFAQAFYTLRI-ASESG-----RSS-SGA------------------QLLPDWIVPDI-P-EIDTLLVAG--A-SAG-SLRTDVLAWLRTTAVQSKRYGSICTGAFILAAT-------GLLKGRHLTTHWAAA---------------------LAEA------YPSADALYVRD--GLRTGAGVTAGLDLAL-------------- +------------------------NFSVFEFATACEVFGIDAFDFRV-TPEPG-----RMK-SGL------------------SLNVSLGLEAT-A-D-DLVIMTP--F-RD--DVPEPVLEALRAAHARGAWVMSICSGAFALARA-------GLLNGRRCTTHWHYSH-------------------ELANR------YPEENVLYV-QD-GLITSAGTAAGIDACL-------------- +------------------------GVSLFHLSVPGIVFGVTPHEVRY-APTPG-----RCD-QGV------------------EIEVPGGLEAM-T-S-DLVIVPA--W-HPE---PAVLTEALKQAHARGAQVVGLCLGAFVLGDA-------GLLDERRATTHWACRD-------------------LFVQR------FPKPDVLYV-DD-GVVTSAGTVAAIDCCL-------------- +------------------------EFNTLDVNGPLEVLRNTNFSITVAAADEH-----TAG-EDI------------------IIKRHISLPEALSSSYSILIVPG--A-PSADPHFAALLDVCEAF-GTERTLLSICTGALMLGYH-------GLFDGLRATTHFMVFD-------------------KLRELCADYA-ERNEPVRWVDAGGVVVSAGGVSCGMDATL-------------- +------------------------HFDNLDLNGPLEVLAG-EWDIVVAAADEF-----TVG-HGY------------------SLRRSITYAEALADSFAALLIPG--A-PDAETHFDGLLDVAEAF-GTERVMLTVCTGSLVPAYR-------GLFDGLRATTHFMAYD-------------------LLTEVSEGYR-KRNPRGRWVDAGGVVISAGGVSCGIDATL-------------- +------------------------GFNTMDMNGPYEVFRMA-FTVTITAEMEV-----TSF-EGV------------------QVKRDIALDHNLLGDFDVLVVPG--G-THLA-KMGDFMKLIAAF-TVPKTLLSICTGALFLGYM-------GIFNGRKCTTHRGAYR-------------------SLQKVNMDAA-AGQIQARYVDAGGTIISSGGVSCGLDASL-------------- +------------------------GFNTLDVNGPLEVLKNS-FEVWVASATEL-----TAC-EGV------------------QIQRNISFQDILDSDIDALIIPG--A-RWGDDGGEGLLKLIREYETKPRWLISICTGSEFLGIN-------GLLQGKPATTHWAAIP-------------------KLEALSEKYV-KTHQRKRFIYSGGVIATSGGISCGIDCVL-------------- +------------------------NFDTLDLYAPIEVLGKGEITFDIAAIAQP-----TSA-EKV------------------PVSPNLSISQAMQDQYEIVVQPG--A-IPEPSSVKEHLQLLLTF-GCKRVFLSICTGALVAGLA-------GVFSNMIVTTHYAGLK-------------------KLRDYCSMAG-VGTQSWRWVTVDGAVISSGGISCGLDASL-------------- +------------------------SANLMDTAGPWEVFQDASFRLHT-AATGS-----TSG-GFV------------------TATHFAITDPH-P-T-HIVVVPA--Q-M-----ALSCQDWLITQAKNGAVILSVCTGAFHLARA-------GLLDRLKAATHHQFWQ-------------------QFSDE------FPHRDQRFI-DN-GILCAGGLTSGIDAAL-------------- +------------------------QADLLDFSGPAEMYSHSPFDVTSFAHSNP-----VAS-PAL------------------VYQPNKTFAEIADTDYDILVIPG--S-DKI-EPGKQLLTLIQNFETGKRFLQSVCTGSLLLAAS-------GVLADRTATTHHLSYD-------------------LLKSIADEAA-GGEVRQRYVDAGGVIVTAGGVSSGIDATI-------------- +------------------------RVLLLDVAGPLEVLRKARFDVHY-GPAPT-----ISS-IGL------------------SVAGVELPQAL-P-G-ALVIVSG--A-DVPAALEKDIVVWLRQAVRPGVRLVTICSGALLAARA-------GLLDGYSCTTHHLTIG-------------------ELERL------APAENRLFV-ED-GRLTSAGITAGIDLML-------------- +------------------------GQVPLDLIGPLQVLQCADVQVRY-GPKAA-----QWL-GPL------------------TLSGIDLPEQL-P-P-DLLLIPG--Q-RNS-LAQQECVGWLKANARYADTLMTVCSGTLLLADA-------GLLEGRRCTTHHALIE-------------------QLRLK------APRSDCIFI-ED-GYLTSAGISTGIDTML-------------- +------------------------MFNILDVSGPVSVLFNTDFSVSYAAKDEL-----TSQ-ENT------------------TIKRDISLAEAKLSDYDILIVPG--S-PNNQGPLSELVEFITCFSMRQRTILAVCMGSYFLAFA-------GVLDGLTATTHRLAVP-------------------GLRDVTQRYV-DRTDLVSYLDAGGVIITTGAMANGIDATL-------------- +------------------------GVDVLDFAGPLEVFSHAAFDVEFIAQSEV-----ITT-TKL------------------RVLRDLSIEEATADSYDILLVPG--G-PDV-SDSPE-LDFIRLFEKKRKTIFSVCTGSLLLGSA-------GLLADLQATSHHMFLD-------------------ELREACKLGG-TPDVCARYIDSGGLIICAGGVSSGLDAAC-------------- +------------------------GVEVLDFAGPMEVFSYA-FKVITVAKTKS-----LSQ-GIL------------------KIIPDYSIKDA-P-QADIFAVFG--G-DE-AADDPEVISWIKSRDSSTKSYFSVCTGAFILGKA-------GLLDQLTVTTFHKSIA-------------------NLQKA------VPKQNVRYVDN-G-VITTAGISAGIDGAL-------------- +------------------------TFNTLDINGPLDVLGNV-FKLTIAAQHDI-----TSA-EGA------------------KIQRHISFITAFEENYDILIQPG--G-SDDDSHFSDMLNIIEEFLHGPRIIMSICTGALFLGSA-------GIFSGLNATTHFLTLP-------------------KLKIICDAYT-ARSLNFRYVKEQKVVISSGGISCGIDATL-------------- +------------------------SLDTLDFTGPLEILSHAVFHNTITAASEH-----TSN-QNC------------------IFKRHISVPEAYATDYDVLIIPGGGV-----TGKTEPLGLIKAFNGRVRTLMSVCTGSLFLGET-------GVLNGLSATTHKNYYG-------------------RLREVCESKG-KTNLQERFVVNKGLVITSGGVSCGLDASL-------------- +------------------------NMNLLDFAGPLEVLTHAAFDITFAGPQEE-----LTA-QGV------------------TLTAHISFKEAHKREFDVLVVPGGKM-----KAEAEPLPLIRAFPARERTLLAIDTASLFLAHQ-------GLLQGLAATTHPDFYI-------------------KLEKECQAAA-ARDMEERYVVNNGMVITSAGAVSGLDASL-------------- +------------------------SVNTLDTNGPIGVLFQ-GYSTVIAARDEF-----TSQ-ENV------------------TFRRDLSIAEAKDTEFDVLIVPG--A-PNHDGHLHELLELISAFPLGERVLFSVCSGSYLLAAA-------GVLDGLTATSHRLGLG-------------------PLRNLCDEYK-SRTGTVHYVDAGQVIVTSGTITNGIDAAL-------------- +------------------------GVDILDFTAPMEVFTHTVFQINTIARSRT-----VAK-KAL------------------TVQTDLLLEDAMQADFDIMVVPG--G-PSL-SNPPE-VDLIRSF-DEPRVLFSICTGAFLVGAA-------GLMTGVSVTTHHRAIE-------------------KLREFCIRVN-GEGSHKRYIDAGSALLTAAGVSSCLDASL-------------- +------------------------QIDLIDFAGPYETIYQALFRIEIAGPGLT-----MTY-QGL------------------TFKQHISYSQVLDADIDLLVVSG--A-WAT-EEFPV-RRIIKEFGRPPRVLLSICSASFFLAVA-------GVLANRRVTTHHLIIK-------------------ELEDLCAKLY-GAGVRKKFVDVGGIVVASGGLTSGFDASL-------------- +------------------------GFDLLDFAGPLEVLSHTAFDVTIASVTDS-----RSA-QGA------------------MIKAHINLKEARESEFEILIVPGGGDRPNDNLSDPGQVPIIKAFPKRERTLLSVCTGSLFLAKA-------GVLRGLYATTHPEYDT-------------------QLEMICQHAA-SHVLSCRYVVNNGLVITAGGVMSGIDAAL-------------- +--------------------------------------------------------------------------------------------------------------QWELASDSHTIKMIEDFYNAGKQIAMVCHAPAILRDAKKL-NGESLVKGLTVTGFMNSEDDELDLS----RHLLFSLKDMLKDNGASYL-------------------------------------------- +-------------------------------------LASAAFNLQVATPGGKTMDVDVSESN---ARWVQ-DFR------LKAYASPAKLESIDGARYHALLIPSCPGALADLASSGSLARILQHFHSESKPICAVGHGVAALCCATN-EDRSWLFRGYSVTGVS----------------------------------------------------------------------------- +------------------------GTEEMEAVILIHVLRRAGAHVTVASVEPQLQVEA---ASG------------------TKLVADASISECSDQIFDLIALPGGMPGSARLRDCDALRIITCKQAEENRLFGAINAAPAVTLLP------WGLLKRKKITCHPAFFHKL----------PT------------FWA-----VKSNIQVSNGLTTSRGPGTAYMFALTLVEQL-------- +------------------------GTEEMEAVILVDVLRRAGAEVTVASVEPQLEVQA---SGG------------------TKLVADTRISTCSDRVFDLVALPGGMPGSAQLRDCEILKKITSKQAEEKRLYGGISTAPAVTLLP------WGLLKRKRTTCHPAFFDRL----------PT------------FWA-----VKSNIQVSGELTTSQGPGTSFLFALALVEQL-------- +------------------------GSEPIESVITIDVLRRSGADVTVASVEKQLRVDA---CHG------------------VKIVADALVSDCRDAVFDLIALPGGMPGATNLKESEVLESIVKKQASAGRLYAAVCASPAVALGS------WGLLKDLKATCYPSFMEQL----------AP------------ACT-----VESRIQQDGKVVTSCGPGTTMEFAVALVEQL-------- +----------------------------MEAVITIDVLRRSGADVVVASVEKQLRVDA---CHG------------------VKIVADALVSNCRDA--------CGMPGATNLKESEVLESIVKKQASDGRLYAAICVFLAVALGS------WGLLKGLK--------------------------------------------------DGKVVTTRGPGTPMEFVVALVEQL-------- +------------------------GTEPVEAAVPIDVLRRAGADVTVASADDELVVEV---MYG------------------VRIVADALVGDCAAAHFDLIVLPGGVPGAANLGGCAALEAMVRRHAAAGGLYAAICAAPPLALAS------WGMLNGLKATAHPLFVDKF----------PP------------EVA-----VDASVVVDASAVTSRGPATSTEFALALVEQL-------- +------------------------GAEPLEAVVTIDVLRRAGAEVTVASAEEQLRVDA---CHG------------------VKIVADALISDCADAAFDLVSFPGGMPGASSLRDCKVLEDLVKKQGADGRLYAASCTFPE--LGS------WGLLKGLKAAIMEQLF---------------------------YFA-----VESRVQVEGKTVTSRGPGTTMEYAVTLVEQL-------- +------------------------GTEPLEAVAMITVLRRGGADVTVASVETQVGVDA---CHG------------------IKMVADTLLSDITDSVFDLIVLPGGLPGGETLKNCKPLENMVKKQDSDGRLNAAICCAPALALGT------WGLLEGKKATGYPVFMEKL----------AA------------TCA-----VESRVQIDGRIVTSRGPGTTIEFSITLIEQL-------- +------------------------GSEEIEVMTIFDVLVRASLGPAIVSLSPQLSP-SQSLPYITLSRGAR-ML--ADTKF-------ETLKQEHKDDFDAIIIPGGAKGADRLSSSREVQTLIRSFYDQGKLVGMICAGSLAAKTS-------GIAGGQRITSHPSVKG-------------------DLEKH-YDYV------EDRVVVSGNLVTSRGPGTALEWALTIVN---------- +------------------------GTEEIEVFTAYDVFVRASLNPVLVSVSPQFSP-SNSLPHITLSRGAR-IL--ADTQF-------ETLKEEHWDLFDAVVVPGGAKGAERLSKEKRVQELLWRFWSEQKLVGCICAGSLAALSS-------QIGLGGALTSHPSVRS-------------------QLEKH-YDYS------DDRVVVAGNLVTSRGPGTALEWALQLVE---------- +---------------------FSTGNHPIETLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHK-DEKVMPFFEQH----KSLFRNPKKLADVNDSEYAAIFVPGGHGALIGLPESRT---------------------------------------------------------------------------------------------------------------------------- +---------------------XXXGAEEMEAVITIDTLRRGGIDVTVAGLAGKTVKCSRMVSPD------------------------TSLEEAHTSPYDAVILPGGLKGSELLSESPLVGQILKQHENGGQIIAAICAAPIAFKS-------HSIALGKQITSYPIMKERLV------------------E--NYKYV------DERVMVDGNVTTSQGPGTAFEFALSLV----------- +MSEKKILEIV----GDFVE--------DYEVMVPYQALEMVGHEVHAACPEKDEGDVVKTAVHDFR--GDQTYLETRGHDFG----VDVALEEIDPADYDALVVPGGRP-------------------------------------------------------------------------------------------------------------------------------------- +------------------------GSEEMEAVAIIDILRRAKANVVVAAL-GNTLE----VVAS---R-------------KVKLVADVLLDEAENSSYDLIVLPGGLGGAEAFASSEKLVNMLKKQAESNKPYGAICASPALVLEP------NGFLKGKKATAFPAMCGKL-------------------ADQ-SH-------IEHRVLVDGNLITSRGPGTSLEFALAIVEK--------- +MAKPQCLLLLSSSS--------EGGIQAQSFIHAFTL-AHSAFNVQLASIEGRLGDDDNSK----------RWI----SDFSKPYSMPLRLDVVEPSRYAALLIPDCTGALYDLTKDRILCDLIRHFVAEKKLICAIGSGVAALCSTKKT-EGKWLFASYCLTAPSVYELARSS----SFASLPIILEDFIKDNAGKYTASE-AGAIHVVVDRCLITGQNEASTIMAVQ-------------- +----------------------SKGYEETEALLVVTYLRRAGIDVDTISTMDTL----ETL---------------GDHDIM--IRADKKWDEINLDDYAGIITPGGVTGSETLAADQRVTKAIKAFHDAGKLVASICASPIVLHAA-------GIAKDIEGVCYPGMEEAV----------------------G--FKKAH---EEIVFFDQNVLTSRGPLTAPFFALKLIE---------- +---HKILVIAADE-RYLPTDGFSTGNHPIKTLLPLYHLHAAGFEFEVATISGLMTKFEYWAMPHK-DEKVMPFFEQH----KSLFRNPKKLADVVDSEYAAIFVPGGHGALGDA--------------------------------------------------------------------------------------------------------------------------------- +---------------------------TLDVFGPVEIFKVPDWKMQFYSRDSGLISNRDGV----------------------QIAT-ESFNTMPQSEIDTLFIPGGTGA-RALILEADYINQLKQLAQKSRYVLTVCTGSALLAKS-------GLLDGKRTTSNK----------------------------------------------------------------------------- +---------------------------ELDLVGSWELILLAEKGLKLISLNSMTPSGEHGM----------------------RFSADYPFTD--PVQPDVLFVPGGSGA-RIAMEDLDVINYLKKTAENCHSVLSICTGMYLMQKA-------GLFKH------------------------------------------------------------------------------------ +-------------------------------MGPVEVFRLEHCQIEFISPSGKAMTRSQGV----------------------TVNT-RPI---LTPFYQYILIPGGQGT-RSLSQNDDYIQWLKKQVEYAETVISVCTGSALLAQT-------SLLNGFKATTNK----------------------------------------------------------------------------- +---------------------------------MASVFYANLLSQQIYS-QGGLIHASYGI------------------------TVDSAPLL-PTSDYDTLIISGDYRA-GFG--SDTLISILKDISVNTRRMASVCSGAFLLAKA-------GLLKNKRVTTH------------------------------------------------------------------------------ +---------------------------QLDFTGPHEVFRLPGAQCVVASAAGGEIHADGGL----------------------TISNVQRLAD--IPHADLICVPGGFGV-IEAMEDAEFVRQVRRLADGARYVTSVCSGSLVLGAA-------GLLQGKRAACH------------------------------------------------------------------------------ +---------------------------QLDLTGPFEVLRVPGVQVELVGKSLEPVRSDRGL----------------------TLVPTTTIAN--APPCDLLVVPGGPGT-DDAILDAEWVGFTRRQAKSAKYIFGICTGSLLLGAA-------GLLRGRRSTCH------------------------------------------------------------------------------ +---------------------------HLDFTGPHQILRLPGAQVVIASEAGGEIEAEG-L----------------------VFARVARLAD--LEHCDLLCVPGGFGV-TQAMADQAYLDQLRRLAAGARYVTSVCTGSLLLGAA-------GLLRGRRAAC------------------------------------------------------------------------------- +---------------------------LLDVAGPTDVFTANEILKHYLSLKSETVTSNSGI----------------------KLQCDASIFN-ITTPIDTLIIAGTHPN-LFENLDETAYTWLKQIYPQVNRLASICVGTFLMAKS-------GLLKNKTVTTH------------------------------------------------------------------------------ +MASKRALVILAK------------GAEEMETVIPVDIMRRAGIKVTVVGLAGKDPVQ---GSRDVV------------------ICPDASLKDAKEGPYDVVVLPGGNLGAQNLSESAAMKEILKEQEKQKGLIAAICAGSTALLAH-------EIGFGSKVTTHPLAKDKT--------------------MNGSHYTYP----ENRVEKDGLILTSRRPGISFEFALAIVE---------- +-----------------------AGTEPVEAAATADVLNRAGARVTVATVASAPAGDEGLLVEA--------AY-------GVKLVADARVADLEGEDFDLIALPGGMPGSTNLRECKVLERMVKMHAEKGELYGAICAAPAVTLAH------WGMLKGLKATCYPSFMEKFT----------------------AEVI----PVNSRVVVDRNVVTSQGPGTAIEFALALVEQ--------- +-----------------------PGFTALDLVGPHYFFAMMGVHLVTNQASLAPVASDLGLA----------------------IAPTTTLADC-PADLTLLFCPGGNGT-IAAASDPATLAFLADRAVRAQCVTSVCTGSVILGAA-------GLLKGRRATSHWVARE-QL------------------SRFGA-TPV-----DERVVRDGKIITGAGVSAGLDLGL-------------- +-----------------------PGMTALDLVGPHHFLAMSGVDLVTIGADLSPVPSDLGLA----------------------IQPTATFGTC-PEDLALLFVPGGMGT-LAAARDPATIEFLRDRGSRARYVTSVCTGSLVLGAA-------GLLRGRKATSHWIVRD-LL------------------SQFEA-IPT-----HGRVVRDGNVVTGAGVSAGLDLGA-------------- +-----------------------DAFETLDVFGPVQMWGLP-HRLMFVSQDGGAVTSAQGTV----------------------VNADASFASA--PQFDILMVPGGMGT-RPLVRDGALLDFVRRQDRATRWTASVCTGAAILARA-------GLLDGREATTNKLAFDWVA------------------GQSDKVWQR-----KARWVFDGKYATSSGVSAGTDMAL-------------- +-----------------------QDFETLDVFGPVQMWGLA-HALGFVTADGQPVRSSQGSV----------------------IVPDWSFASA--PQFDVLMVPGGQGT-RPLVEDAALLGFVRQQDGSTSWTTSVCTGAAILARA-------GVLDGRNATSNKRAFDWVK------------------RQSDKVWHG-----RARWVVDGKYVTSSGVSAGTDMAL-------------- +-----------------------DGFETLDVFGPVEMWGLP-YEMVMVSQHGGPVKSAQGIE----------------------TIAPLSFANA--PQFDILMVPGGAGT-RTEVNNPELLAFLRKQDHGTEWTTSVCTGSALLAKA-------GILDGRKATSNKLAFRWAA------------------SQSDKVWQT-----HARWVIDGKYISSSGVSAGTDMAL-------------- +-----------------------DGVEELDFAGPWEVFGWSQYRPVSISLDSRQVRCAQGLE----------------------VVAQHTYHEA--PPLDVLLVPGGKGW-RRLVNEPASIAKIQKLTEHVNLVASVCTGSLLLAKA-------GYLRNRRATTHWSELDTLT------------------TLDPTIVDR-----DSRYVDGGEYVTSSGVSAGVDMAL-------------- +-----------------------DGVEELDFAGPWEVFGWAQYKPVSISLASRQVRCAQGLD----------------------VVAQHTYEAA--PPIDVLLVPGGKGW-RTLVDQPESIAKIQKLTERVELVASVCTGALLLAKA-------GFLKNRRATTHWSALDTLT------------------QLDSTIVDR-----NSRYVDGGNYVTSSGVSAGVDMAL-------------- +-----------------------DGVNDLDFMGPRYVLGT-GTRLI--GLKPGPIKTVTGVQ----------------------VVPDAVID-E-VTRLDILIIPGGTGT-IEAAYDDRVLDWIRTIDKGTIYTGAICTGVWILGAT-------GLLEGRQAVSHWYREEEFL------------------RKYKA-IPA-----NKRYTHDGKYWTSAGVTAGMDMSL-------------- +------------------------------------------------------------------------------------YASPAKLESIDGARYHALLIPSCPGALADLASSGSLARILQHFRSESKPICAVGHGVAALCCATN-EDRSWVFQGYSVTGPSVYELIRAPG----FARLPLIVEDFVKDAGAIFS-------------------------------------------- +------------------------------------------------------------------------------------FYDQLILSSFLGARYHALLIPNCPGAVTDLANSGYLARILQHFCTESKPICAVGHGVAALCCATN-EDKSWVFQGYSLTGPSVYELVRQPN----FASLSIIVEDFVKDSGATFS-------------------------------------------- +-MLKHVLMIVSKFA--NGITATSEGISAAELIHPYDVFRMANCKVTIASSRGGAVVDPSDLSGSNLDPLSARYI--AQPRFIKRLMNTPAISELNISDYDAIFVCGGEGTLYT---------------------------------------------------------------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------FSFDNFDVLFLPGGIPGTPNLRACEPLCNALRAHNEQGKRIAAICAAPSILAEL-------GILSGKRATSNPAFQH-------------------VLSENGATVE------QEYVVRDGNLFTSQGLGTAMDLGLALV----------- +--MSSILFVFTSADKTL--TGAQTGYYLPEAAHPYYVLAP-HFKIDFASPKGANPLDESSVK-MFADNESVQWL--NDETVKAKLASTKKLTEVNPDDYDVTVQPS----------------------------------------------------------------------------------------------------------------------------------------- +-----------------------SSVTQLDFTGPYEVFRIPNAKIFLFAQSKGPVVAESGMK----------------------LIPDYDFSN--CPDFDILLVPGGAG-TTLLMEEFEVLNFLKTKAENSKFITSVCTGSLVLAAA-------GLLDGYKATTHWLSLD-------------------VLKLFPVQIS------GERFVKDRNRITGGGVTAGIDFALF------------- +-----------------------SGVTQLDFTGPYEIFRIPNVRIFLFARSKEPIVAESGMT----------------------WIPDYDFSN--CPDFDILLVPGGAG-TTLLMEEFEVLNFLKTKTENSKFITSVCTGSLILAAA-------GLLDGYKATTHWLSLD-------------------VLKLFPVQIS------GERFVKDRNRITGGGVTAGIDFALF------------- +-----------------------PNLNLLSFTASYEVFYLPDARVYLLAPTLDPIHSESGIR----------------------LFPNTTFAK--SPNLDVLFVPGGLG-INARLEDTAFLNFLETQGKHARYVTSVCTGSLLLAGA-------GLLQGYRATTSWSALE-------------------LLAMFGVETV------AERVVIDRNRITGGGVTAAIDLGLA------------- +-----------------------PDLTQLDLTGPYEVFRMPDSEILLLAETKEAVRSEKGLS----------------------ILPDRTWEE--VSDLDLLFVPGGIG-VNPMMENKNLLSWIRARSESCKYVTSVCTGSLVLAAA-------GVLDGYKATTHWLSIP-------------------VLELFPIGIS------TDRVVIDRNRITGGGITAGIDFALR------------- +-----------------------PGLTHLDLTGPHEVFRMPNTKISLVAEEAIPILAERGLA----------------------ILPDLSIQD--SPKFDLVFVPGGTG-VNAVMENEKILFWLKDQAKTAKFVTSVCTGSLALASA-------GLLEGYSATTHWLSLD-------------------ILRLFPVNVK------EDRIVRDGNRITGGGVTAGIDFALS------------- +-----------------------PQLTQLDLTGPYEVFRLPDTQVLLLAHTLAPIATEKGLS----------------------ILPNCSFAD--SPQLDVICVPGGPG-INACLTDEVMLDFLRQQSIKAEYVTSVCTGALILAAA-------GLLEGYQATTHWLSLD-------------------LLRMFRVDVR------TERVVQDRNRITGGGVTAGIDFGLT------------- +-----------------------PDLTPLDFVGPYEVFRMKNSKVHVIAETKDPVPSERGLF----------------------ILPDRSLYE--NIDLDLVLVPGGLG-VNRLMENERILNWLREKSKTSKYISSVCTGSLVLAAA-------GLLNGYKATTHWLSLD-------------------VLRLFPIDVQ------EDRVVIDRDRITGGGVTAGIDFALQ------------- +-----------------------PDLTPLDFVGPYEVFRMKNSKIYVIAETKEPIPSEKGLF----------------------ILPDRTMDE--NIDLDLVLVPGGLG-VNRLMENEKVLSWLREKSKTSRYISSVCTGSLVLAAA-------GLLNGYKATTHWLSLD-------------------VLRFFPIDVK------EDRVVIDRDRITGGGVTAGIDFALR------------- +-----------------------PGVTQLDFTGPYEVFRIPNVKIFLFAQSKDPVQSESGMK----------------------LIPDFDFAD--CPDLDILLVPGGPG-TTLLMEEFTVLDFLKRKTVNSRFITSVCTGSLVLASA-------GLLDGYKATTHWMSLD-------------------VLKLFPVQIS------SERFVKDRNRITGGGVTAGIDFALF------------- +-----------------------PGVTQLDFTGPYEVFRIPNVKVFLFAQTKSPITAESGMK----------------------LIPDYDFSD--CPDLDILLVPGGSG-TTPLMEEFEVLNFLKTKAENSKFITSVCTGSLVLAAA-------GLLDGYKATTHWLSLD-------------------VLKLFPVRIS------GERFVRDRNRITGGGVTAGIDFALF------------- +-----------------------PDLTHLDLTGPHEVFRIPNTKLSLVAEAVVPILAERGLA----------------------ILPDLPLQD--SPKFDLVFVPGGTG-INAVMENEKILSWLTNQAKSAKYITSVCTGSLALAAA-------GLLDGFSATTHWLSLD-------------------ILRLFPINVK------EDRIVRDGNRITGGGVTAGIDFALS------------- +-----------------------PGVTQLDFTGPFEVFRIPNAKVFLFAQTKGPITTESGMK----------------------FLPDYDFAT--CPDLDILLVPGGSG-TTLLMEEFEVLDFLKSKAENSKFITSVCTGSLVLAAA-------GLLDGYKATTHWLSLD-------------------VLKLFPVQIS------GERFVRDRNRITGGGVTAGIDFALF------------- +-----------------------SGVTQLDFTGPYEVFKIPNVKIFLFAQSKEPVVAESGMK----------------------WIPDYDFSD--CPDLDVLLIPGGVG-TTLLMEEFEVLNFLKTKAENSKFITSVCTGSLVLAAA-------GLLNGYKATTHWLSLD-------------------VLKLFPVQIS------GERFVRDRNRITGGGVTAGIDFALF------------- +-----------------------PQVQQLDLTGPHDVFSLPGVTVRLVWKTREPVASSSGLV----------------------LAPNATFDD--CPPLDVICVPGGIG-VADLMEDADTLAFLRRHAAHARYVSSVCTGALVLGAA-------GLLRGRRATTHWAFHS-------------------LLAPFGATPV------RERVVRDGNLVTGGGVTAGIDFALT------------- +----------------------APGCEEIEALTPVDALRRLGVKVDMVGLESTDVM----GAHGI------------------KLTCDK-VMDESLLDYDIVIFPGGSKGADNLRDSDQLMDLIQQRHAAGKWNAAMCSGPVAFARY-------GLLDNCTYTCFPGVEKQ---------------FENDIKN--ATHS------DEIVVVDGKIITSRGPATAMAYAFKI------------ +--MKKFLGIITNVSKYP-SAEKPTSLWLGEAVHFAHEVEKAGYAVDYASHKGTYT-------------------------------------PIDPNDY-----AGGHGAVWDFPDNAALTQVAH--LQPWRCGVLVCHGSARLLNIEQ---------------------KALQ----LDKLVPYLTEDALVARGLSMK-------------------------------------------- +------------------------------MTGPYEVLANPGFTVDFVAKTRDPVRCDRGLQ----------------------FVPTQTLASAP--PCDLLVVPGGPG-TDDAIVDADWVAFTRTQGLAAQTIFGICTGSLLLGAA-------GLLRGKRASSHWRARE-------------------LLSRFGAIPS------DERLCVDGNIYTAGGVTSGIDMGLKVV----------- +------------------------------VAGPFHFLAATGATVEFVSPSDEPVPSGNGVT----------------------LMPTSTISDTFT-APEVLLVPGGD--TGILLRDNQAMTELKRLGKEATYVTSVCSGSIALAAA-------GLLHGHRATSHWSVRH-------------------LLTGYGAIEV------NERIVEDGNRLTAAGVTAGMDLGIRLV----------- +------------------------------LTGPFEVLARPGFKIDLVSPTMDPVRSDRGLT----------------------LAPTATFDNAG--PCDILVVPGGPG-TDDALVDPAWVDFTARQAADAKFILGVCTGSLLLGAA-------GLLRGKRAACHWQARA-------------------FLVSFGAIPD------ESRTCIDGNIITSGGVTSGIDMALRAV----------- +------------------------------ITGPFEVLARPGWTVDLVAATMDPVRTDRGLR----------------------LVPNVTRETAK--KSDIIVIPGGTG-IDTVMLDPQWVAYVKQEAKRSQYIFGICTGSLLLGAA-------GLLQGRRAGGHWQARD-------------------LLTNFGAIVS------NDRMTQDGNIYTSGGVTSGIDVALRVI----------- +---------------------------------------------------------------------------------------DYDFSEVD--SADILVVPGCSPPYKTPMNDQVTLNWIRQIHKTTKWTTSVCNGSLILSAA-------DILNGTIATCHWGSFD-------------------LLRSLGTIPT------DERVVRQGKIVTAAGVSSGIDMALHI------------ +----------------------------------------------------------------------------------------------------MLLVPGG--PAADLLADQPTLDWLRGVDAAATWTASVCSGSLLLAAA-------GLLTGRRATSHWICLD-------------------HLTTFGAIAT------AERVVIDGKYATAAGVSAGIDLALHL------------ +---------------------------------------------------------------------------------------DAAFDELT--RPDVVIFPGG--ITRTLIHDQTVLDWVREAHRHTLLTTSVCTGGLVLAAA-------GLLNGLTATTHWRVQD-------------------LFNSLGARYV------PQRVVEPERVITAAGVSSGIDMGLRL------------ +--------------------------------------------------------------------------------------------------MDVLCIPGG--AINALLLDDEIVNWVRQQASAARWITSVCTGALLLGTA-------GLLAGRRATTHWRYHD-------------------LLSTFNAIPV------RERVVQDGNLITGGGVTAGIDFALAV------------ +---------------------------------------------------------------------------------------DADIASVR--AADLLIVPGGHRRIAATIPDRDVQDWLSAIDAGSRWTTSVCTGSLILAAS-------GVLAGRSASTHWRAKS-------------------ALARYGVDYS------AKCVTIDGKYVTSAGVSAGLDMGLYL------------ +---------------------------------------------------------------------------------------TERLADIE--QTDVILVPGGSD-LTAPMR-PAYQAQIRRLAESAKHVTSVCNGSLVLAAT-------GVLNGKRSACHWAFVN-------------------KLSQYGAIPV------PERFVENGRFMSGGGVTAGIDFALRV------------ +---RGVLIILP-----------REGFDELQYTIAWARLRANGIPFSLASSPGGVARGQL----------------------GMEVALDLPVSRVNPEDYRGLLLLSGPG-VQSLIEDASVQGLVEQWGEEGRPVAALEGAPAVLAQA-------GLLTGRQAVCWPTWRG-------------------QVRQFGAEIMP------GITARAGFILTGLGGSDEN------------------ +---QRILVLLP-----------DAGLDDLQFTIAETRLSLAGNTLTYASLSGGSAVTVH----------------------NRTIYNCRKLNTLDPSQYDALLLINGAQ-RSTFASDPDFIRICTHLIHRDKPIAASGYAT--AALA-------PFLNGMKASAFPSEKP-------------------TLERSGAVYTR------ALVTADRNFLTGFGGSDEN------------------ +------------------------------------------------------------------------------------------IEDVKPRGYDAVIFTGGSGLYRR-VKSGHVAGIAESASRSGKIIGAICAAPAIPAMA-------GILRGQNATIYPGLEG-------------------VLSENGARYVK------GDVVVSGRIVTASTPESAGKLRDT------------- +-MAKKALVLVAD------------GTEEMEFTITYDTLVRAGVECTSANVQGGSPYGTVGTSPALVV--CS-----RGIKI--LPDTTLQPLEAGPDKYDALVIPGGLKGSETLSQSTEVQTLVREYFNAGKIVAMICAGTLAAKTA--------GLPHQPVTSHPVVQD-------------------VLTQA-FKYEEGSVVVSDKVEGKGTLVTSRGPGTAFPFAFKLVE---------- +-----------------------AGTEPVEATVPIDVLRRAGAHVTVASADFGGLVVEAMYGGRI--------V----------AAALVAPDDSAAARFDLIVLPGGVPGAANLGGCAALEAVVRRHAATGGLYSAICAAPPLALAS------WGLLDGRKATAHPLFVDK----------FPP------------EVAA----VDASVVVDGSAVTSRGPATSSEFALALVEQL-------- +-----------------------AGTEPVEAAVPIDVLRRAGADVTVASADDGELVVEVMYGVRI--------V----------ADALVAGGDCAAAHFDLIVLPGGVPGAANLGGCAALEAMVRRHAATGGLYAAICAAPPLALAS------WGMLNGLKATAHPLFVDK----------FPP------------EVAA----VDASVVVDASAVTSRGPATSTEFALALVEQL-------- +-----------------------AGSEPVEAFVPIAVLRRAGADVTVAAAGGAGLRVHAMYGVTV--------V----------ADANVA--DCADASYDLVALPGGVPGADNLGGCAALESIVRRQALGGGLYAAICAAPPLALAR------WGLLDGVKATAHPAFVDK----------FPA------------EVAA----VDANVVVDGRVVTGRGPAPAMEFALALVEQL-------- +-----------------------AGSEPAEAFVPIAVLRRAGADVTVAAAGGTGLRVHAMYGVTV--------V----------ADASVA--DCADASYDLVVLPGGVPGADNLGGCAALEGIVRRHALGGGLCAAICAAPPLALAR------WGLLDGVKATAHPEFVDK----------FPA------------EVAG----VDANVVVDGRVVTGRGPAAAMEFALALVDQL-------- +-----------------------AGTEPVEATVPIDVLRRAGAHVTVASAADGQLVVEVMYGVRI--------V----------ADALVAD--QADDHFDLVALPGGVPGAANLGGSAALEAVVRRHAGRGGLCAAICAAPPLALAS------WGMLNGLKATAHPLFVDM----------FPP------------EVIA----VDASVVVDGNAVTSRGPATSTEFALALVEQL-------- +---------------------------------------------------------------------------------------DKTVGEISLKDIEGLIIPGGSDR--ILK--PELELLIKKLHEEKKLVAAICAGPEFLAKS-------GILNGRKYTTTVPP--------------------------------------------------------------------------- +---------------------------------------------------------------------------------------HIELSEVRVDEYEGIIIPGGDAV--HMK--DALFSVIRQFSEKEKLVAAICAGPYALARA-------GLFKGISYTATIDY--------------------------------------------------------------------------- +---------------------------------------------------------------------------------------HIELGEVRVEEYEGIIIPGGDAI--HME--DALFSVIRQFHEQEKLVAAICAGPYALAKA-------GLFKEVSYTVTMDY--------------------------------------------------------------------------- +---------------------------------------------------------------------------------------TKTLEQISIDDYSCLILPGMIDF--KPAL-RDLLTFLAGLNEESILIAAISSAPILLAKA-------GLLKDKTFTGGIDY--------------------------------------------------------------------------- +MASKRALVILAK------------GAEEMETVIPVDIMRRAGIKVTVAGLAGKDVQCSRDVV----------------------ICPDTSLEEAKQGPYDVVVLPGGNLGAQNLSESALVKEILKEQENRKGLIAAICAGPTALLAH-------EVGFGCKVTSHPLAKDKMM---------------------------------------------------------------------- +------------------------GSEEMEALNLIDVLRRAGARVTVASVEDTP----RILTR---------HYKL-------NLIADVMLEQAAEMEFDLIVMPGGLPGALKFTSSEKLVGMLKKQAESGRPYGAICASPAYVLEP------HGLLKGKKATSFPPMAHL-------------------LTDQACEY---------RVVVDGNLITSRAPGTATEFALAIVEK--------- +----------------------ADGTEPVEAAATADVLNRAGARVTVATADPAG--DDRGLLV----E----------AAFGVKLVADGRVADLEGEAFDLIALPGGMPGSANLRDCKVLEKMVKKQAEQGGLYAAICATPAVTLAH------WGLLKGLKATCYPSFMEKF----------------------TAEII----PVNSRVVVDRNAVTSQGPATAIEYALALV----------- +----------------------ASGTEPMEAVITVDVLRRAGADVAVASVDPGS--AQ----V----G----------GAWGVKLAADALLADLADAEFDLISLPGGMPGSSNLRDCKLLENMVKRHAGKGKLYAAICAAPAVALGS------WGLLNGLKATCYPSFMDKL----------------------PSEVN----AVESRVQIDGNCVTSRGPGTAMEYSVVLV----------- +------------------------------------------------------------------------------------------------ENLSFVHLPGGHAPMVDFLDNPELGEVLNQLSEQKVITSLICHAPIALTSARLRIKDKSLYEGAHITTVPKIGELFMLISGYKKTRLHYYVDKKLISYNFNVKT-TKNFTSLVVYDRKLLTGNGPQAID------------------ +-----------------------NGSEEMEALNLIDILRRAGANVTVASVEDKLQI-----V----T---------RRHKF--NLIADIMVEEAAKREFDLIVMPGGLPGAQKFSSTKVLVDLLKKQAESNKPYGAICASPAYVLEP------HGLLKGKKATSFPPMAHL-------------------LTDQSA--------CDSRVVVDGNLITSKAPGSATEFALAIVEK--------- +-----------------------NGSEEIEALNLIDVLRRAGANVTVASVEDTLQ-----IV----T---------RRHKF--NLIADMMLDEAAKMEFDLIVMPGGLSGAQKFASTNKLVDLLKKQAGSGKPYGAICASPAHVLEP------HGLLKGKKVTAFPPMAHLL-------------------TDQ---SL-----CENRVVIDGNLITSRAPGTATEFALAIVEK--------- +------------------------------------------------------------------------------------YASPAKLESIDGARYHALLIPSCPGALTDLASSGSLARILQHFHSESKPICAVGHGVAALCCATN-EDRSWVFDSYSLTGPSVCELVRAPG----FARLPLVVEDFVKDSGACFSG------------------------------------------- +-----------------------PNMTPLDIVGPVTMLQNHGFNVEYVYHDKNPVPTEISL----------------------SLMPTATFSELN--SADILCVTGTHNP-FNAIADKKMLDWINTVGKRAEYVTSVCTGGIIIAAA-------GLLDGYKASTHWSFQD-------------------TLAALGATPS------DERVTVDRNRITGGGVTAGIDFGL-------------- +-----------------------PGMTPLDIVGPVTLLQNQGFTIEYVWHNKQPISTEICL----------------------PLTPTITFDELD--AVDILCITGSHNP-FPALKDIKMLKWIHKVGQRAKYITSVCNGSLFLAAV-------NLLDNYESSTHWSCNE-------------------FLAKLGATVS------NERITIDRNRITGGGVTAGIDFGL-------------- +-----------------------PELTPLDLVGPATVLEDRGFNVEYVWHNREKINTEISF----------------------KFYPSITFDELE--YVDILCVPGALDP-FSIMRDEKAMRWLNKVGKNAEYVTSVCTGSIILAAA-------GLMNGYKAATHWLMGE-------------------YLTEFGAIPV------HERVVIDRNRITGGGITAGIEFGL-------------- +-----------------------PGLTLMDLLGPQTALS--SCNVHLVWKSRDFIESDTGI----------------------GLRPTATLADCP--KLDAIFVGG-PGQ-FGIMNDSKVIGFLADRGSRAKYVTSVCSGSLLLGAA-------GLMRGYKATSHWACRE-------------------YLPLFGATPV------DARVVVDRNRVTGGGVTAGLDFGL-------------- +-----------------------EGMTVLDLIGPAEVLG-PQFRVDYVSRSMAPVYAESRL----------------------GFMPTATFANVA--SADIVCVPGTSDP-YLQIQQQDMVEWLAAVGQKAQWVTSVCTGSFLLGAA-------GLLQGYKATSHWTLVD-------------------ELAWFGALPV------QERVVRDRNRVTGAGVTSGIDFGL-------------- +-----------------------DGITAQDMIGPATVLGSGQFTMDYVWRDRNPVRAESEL----------------------HIVPTATFKEVR--NADILCVPGTSNV-FAQLRQPDILDWVARVGAKAAWVTSVCTGSFILGAA-------GLLNGYKATSHWTLVD-------------------ELAAFGAIPT------RERVVADRNRLTGAGVTSGLDFGL-------------- +-----------------------PGMTVLDLIGPQSMFAMMGARIHLVAKTLDPVTSDAGV----------------------TITPDATFETCP--RLTVLFAPGTDGT-IKAATDHATLAFMADRGSRATYVTSVCSGSLILGAA-------GLLKGFRATSHWSCRD-------------------ALAGFGAIPT------DARVVRDRNRITGAGVTAGLDFGL-------------- +-----------------------PGMTVMDLVGPHCMFGLMGVKIHIVAKSLEPVTSDAGL----------------------TVVPTVTFDTCP--QLTVLFTPGTDGT-LAAASDPETLAFMADRGARAKYVTSVCSGSLILGAA-------GLLKGYKATSHWSCRE-------------------ALAGFGAIPT------EARVVRDRNRITGAGVTAGLDFGL-------------- +-----------------------PGMTVMDLVGPHCMFGLMGAKIYIVAKSLDPVTSDAGL----------------------AIVPTATFGTCP--RLTVLFAPGTDGT-LAAASDAETLAFMADRGARAKYITSVCSGSLILGAA-------GLLKGYKATSHWSCRD-------------------ALAGFGAIPT------EARVVRDRNRITGAGVTAGLDFGL-------------- +-----------------------PGMTVMDLIGPQCMFGMMGAKIHLVAKSLDPVTSDAGV----------------------TIVPTATFESCP--RLTVLFAPGTDGT-LAAAADPATLAFMSDRGARAKYITSVCSGSLILGAA-------GLLKGYKATSHWSVRD-------------------VLAGFGAIPT------EARVVRDRNRVTGAGVTAGLDFGL-------------- +-----------------------PGMTPLDMIGPATVLAGEWLNIEYVWRDLLPVRTELHI----------------------SFSPSITFEQLD--KVDILCIPGTGNP-YALLTELDMLDWIHKVGSKASWVTSVCTGAILLGAA-------GLLKGYKAATHWSMMD-------------------DLGKFGAMPI------NKRVVIDRNRVTGGGVTAGIDFGL-------------- +-----------------------PGMTPLDIIGPATMLGGENFDIHFVWRDRNPVHGEMHV----------------------QFLPSTTFRELK--KVDVLCITGTGNP-YALLKEHEMIDWLHEVGGKAEWITSVCTGSILLGAA-------GLLQGYQATTHWSMID-------------------DLKPFGAIPV------NDRVVIDRNRITGGGVTAGIDFGL-------------- +-----------------------PGMTPLDMIGPATVLEGGWLNIEYVWRDLLPVRTELYI----------------------SFSPSTTFEQLD--KVDILCVPGTGNP-YALLAELDMLDWMHKVGNKASWVTSVCTGSVLLGAA-------GLLKGYQAATHWSMID-------------------DLNEFGAIPV------NKRVVIDRNRVTGGGVTAGIDFGL-------------- +-----------------------PGMTPLDLVGPATVLRNPHLNVEFVAHDLQPLSTELFL----------------------QFLPTTTFDRLK--QVDILCVTGTGNP-YAHLQDTKMLDWMHKVGSKAEWVTSVCTGSILLAAA-------GLMKGYKATTHWSMID-------------------DLKPFGAIPL------DERVVIDRNRISGGGVTAGIDFGL-------------- +-----------------------PGITPLDMIGPATILTGEWLNIEYVWRDLLPVRTELHI----------------------SFSPSITFEQLD--KVDILCVPGTGNP-YALLNELDMLDWIHKVGSKASWVTSVCTGSILLGAA-------GLLKGYKAATHWSMMD-------------------NLSKFGAIPV------NKRVVIDRNRITGGGVTAGIDFGL-------------- +-----------------------SGVEILDLAGPMEVFAYAGYEVVTISKTKEPIYAQGIL----------------------TVIPDYDLSDAP--EVDILVFFG-GNA-MLPSKDQELIDWIKSL-KETKYHFSVCSGALILAAS-------GVLDGKQATTFRYTLD-------------------ILEKEVEVIR------GARYVDNGKVVTTAGVSAGIDGAL-------------- +------------------------------------------------------------------------------------------------PQIDLLIVVGGVHR--NEMNKSNVLHWVASVDKHAKHIASVCTGAFILANA-------GLLKGLAVTTHWEDIP-------------------ELKQRFPDLVVVE---DKRWITASKYTTSGGISAGIDM---------------- +------------------------------------------------------------------------------------------------PPLDVLHVPGGRGARETQLHNPVVTDWIGKTAEQAAWVHGVCTGTFLLHAA-------GTARGRRVATHWSQED-------------------TLEAR-GDVTVVR---DARYVVDGDLVTSQGVSAGIDS---------------- +------------------------------------------------------------------------------------------------PAIDCLIVPGGVVT--AELEKPDVIHWISDQSEPGRVVAAVCTGAFLLART-------GKLAGKQVTTHWEDID-------------------DLKEMFPSVDVLS---TLRWVDEGSFVTSAGISAGIDM---------------- +------------------------------------------------------------------------------------------------PGADVVIEPGGDGSLE-RLRNESHRGWLQEAAQRGAIVASVCTVARLLAAA-------GLLHQRPFTTYHDTFD-------------------SVAALDPKAQPCP---GQRWIDDGQVITDAGVSAGIDM---------------- +--------------------------------------------------------------------------------------------------LDVLFVPGGMGTRAPAPELDAHIAYIRETYPSLQYIVSVCTGSWLLARA-------GVLDGKNATSNKRAWA-------------------GTAELGNGTNWIT---HARWVQDGNIWTSSGVSAGIDG---------------- +------------------------------------------------------------------------------------------------------MLPGGRTATKLLCLEPKKLETIKAAAQEADICMMIANASSILAQT-------GLLYHRQIADYPGDQN-------------------WKRMFTAEIRRAE---DVRWISDGKYYSSSSTMAGFDM---------------- +----------------------------------------------------------------------------------------------------MLIVPGGGWNHRKQAELGTLTKMISEMHNAGTIVAGVCTGGMLLAAS-------GILNGRKATMHCFAQD-------------------EMSEYGAE---LL---HYRIADQGDIITARGVTSGVDL---------------- +------------------------------------------------------------------------------------------------NRPDLLIVPGGGWNHRKQAERGTLTKMIREMHNEGTIVAGVCTGGMLLAAS-------DILNDKKATMHRLAQN-------------------EIRTYGAE---IL---PYRIVDQGDIITARGVTSGTDL---------------- +-------------------------------------------------------------------------------------------------------------AMYDLHYDLSSLDLIRAF-------SAVGHVPTVFIKKPSPKSGLPLLS-NAVTGFSNIEEDQAGMT----SIMPYMLEDELNRVGGGYVKADQPWGEKVVVDGSLITGQKPASAAGVRR-------------- +----------------------------------------------------------------------------------------KTCSEFCKDDYDCLILSGCSD-LRQPIRNKKIKEFLENFVNDSFVIGAICSSPIFLAQA-------GLLKGKKYTDSLFV-E--------MRESFA----------FIEENNF---LPQSVVEDGNIITAVGNA--------------------- +----------------------------------------------------------------------------------------KVCSEFCKEDYDCLILPGCSN-LTQPIRNKKIKEFLELFANDTFIIGAICAGPVFLAQA-------GLLKNKKYTASLYA-E--------MMELFN----------FVEEENF---LPQSVVEDENIITAVGSA--------------------- +----------------------------------------------------------------------------------------ITYEEFCVEEYDCLILPGCSD-IRQSIRDEKFMEFLRGLEGNTFPIGAICAGPIYLAKA-------GLLKDKKFTNSMYL-E--------MNERLP----------FIDMENI---RYQPVVEDGNVITAQGDA--------------------- +----------------------------------------------------------------------------------------KTCDEFSPEDYDCLLLSGCSD-IRMALRNQKLNTFLKSFKDNDFIIAAICSAPLFLAHA-------GLLRGKKYTDSLFM-E--------MRSLFY----------FIEEENF---LPLPVVEDGNIITANGAA--------------------- +----------------------------------------------------------------------------------------KTCSEFHAEDYKCLILPGCSD-IRDAIHNQKLKMFLESFRDNDFLIGAICSGPVFLAQA-------GLLQGKRYTDSLFV-E--------MREQFP----------FIEEQNF---IAAPVVESENIITAGGSA--------------------- +----------------------------------------------------------------------------------------KTFEEFHKEEYCCFIIPGGAE-LAYAFADEKLFQFLRSFKGEDFPIGAICAGPLFLSMS-------GLLKGKKFINSMGD-D--------FNARFH----------GVEYENI---VYAPVVCDGNIITALGEA--------------------- +------------------------GVDLADVASAWRVLSEAAVDVVFATPRGAVPVDEALLSAAP---RD-VQFEAAQLMEASTFCEPLDVCDAHPDAYAGLYLPSGLSVEYAMLESREVALAVAQFWAAGLPIATVGGAVLVLSKVTVPGSTSSLLDGRAVTTLPGSAQRKTRLISQYSDAGTF--AAQLERVGVSLMKPVPDAAGYVVSDGQLVSGRWWGDAYAAAAALV----------- +-----------------------DGTEEIELTCITDILRRAEIQVTVASVMESQNL---ILSRG---------L---------KITTDSLLKDESAAAYDGVFLPGGLPGADHLGKNAHLKKILEEMRSQGKWYGAICASPVLALAPM------GMLEGKTVTCYPAMKEKI-------P-------------SHVHWS------TDPVVRYGKCLTSKGPGTAIAFGLAIVA---------- +------------------------------------------------------------------------------------------------------------------------------MKKSDKYIGAICAAPYALDAA-------GVLSD-NFTCYPSIET-------------------KIRLD-GYDKN------TGTIIDGKIITSQAVGTAVCFALEIVKI--------- +------------------------------------------------------------------------------------------IDKIDITDAEALILPGGMPGSSNLNSCEQLKEMLLDQYRRGKIVAAICAAPMVLGSL-------GLLKGRKATCYPGFEL------------------------------------------------------------------------- +TGTHRVAILV------Y------DGVKLLDVAGPAEVLGEADYRIALVSTTGADVVSSIGMR----------------------VAVDGSAAT--APDPDTFLVPGGDV-HPRTPVPRDLADAARDLAARAGRVASVCSGAFVLAAT-------GLLDGKRATTHWKIAGEL----------------------------------------------------------------------- +SGPRRIGFLL------F------DGVKALDYIGPAEVFVEEAYDVVLLSPSGAPVQTSVGGG----------------------VAVAMAAAD--APALDTLVVPGSEV-SPDEFVRPDLVAAARLLAARSRRVVSICSGAFVLAEL-------GLLDGRAATTHWKFADEL----------------------------------------------------------------------- +--MTIVGILV------G------PGRRAFDIEVAREVYDDPQPEVRIAARAITDLDPLHS------------------------MRRTHALSS--ADQLDILVVPGCVD-PLAAPR-AEELSAVARAAAAGALVASLCTGAFTLAAA-------GLLDGRAATTHWRFAEEL----------------------------------------------------------------------- +AARRRIGFLL------F------DGVKALDVIGPAEVFAEDTYDLVFLSASGRDVMTSMGLA----------------------FGVHAAASD--SGPLDTIVVPGSEW-APDVFDDADLRGAIVLLSRRARRVASICSGAFGLAAV-------GLLDGGPATTHWKFADEL----------------------------------------------------------------------- +PTPRRIAFLL------F------DGVKSLDYVGPAEVFVEHGYDVVMLSPDGRDVSTSLGGT----------------------VSVQGAASD--AGEFDTVIVPGSEL-PPCDFARTPLTDAAADLVSRSRRVVSVCSGAFVLAEI-------GVLDGRRATTHWKFAPEL----------------------------------------------------------------------- +GQRRRIGILL------F------DGVKALDFVGPAEVFSEDAYELRFYSPTGADVTAFMGLR----------------------IGVDGAASE--SGPLDTVIIPGSEL-APGVFDDADLQRAITTLARQARRIASICSGAFGLAAT-------GLLDGHPATTHWKFADAL----------------------------------------------------------------------- +PAPRRIAFLL------F------DGVKTLDYVGPAEVFVERGYDVVLLSPDGHDVMTSLGTT----------------------VSVHGAADD--AGDFDTVIVPGSEM-PPHEFARGPLTDAAAALATRARRVVSICSGAFVLAEI-------GALDGKRATTHWKFAPEL----------------------------------------------------------------------- +HARRRIAFLL------F------DGVKMLDYVGPAEVFVEDAYDIVLLSPDGNDVVTSLGSR----------------------VSVHGAVHD--AGEFDTVILPGSER-PPHEFVRSPLTEAAASLASRARRVVSICSGAFVLAEI-------GMLDGRRATTHWKFAPEL----------------------------------------------------------------------- +NAPQRVLFVL------F------DGFQPLDLAGPWQAFSSALYQLNTIAAERVVSTWEQGLR----------------------MQVDGTFEEDGDAPVDMLLVPGGPG-VDRASAHAETRAWLRRRDAGAARTCSVCTGAFVLAAA-------DLLNGLAVTTHWRSADRL----------------------------------------------------------------------- +-----MLFVL------Y------DGFQPLDLAGPWQAFSSKLYQLHTIAATPVVATWEQGLR----------------------MQMDGTFADDADAPVDTILVPGGPG-ADLASAHRETQAWLRRRDPDTRRTCSVCTGAFVLAAT-------GLLDGLAVTTHWRSATRL----------------------------------------------------------------------- +---MRVQFVL------Y------DGFQPLDLAGPWQAFSSKLYRLGTIAATPLVSTWEQGLR----------------------MQVDGTFADDGDERLDMMFVPGGPG-ADFAGAHGETRAWLRRRDATAGRTCSVCTGAFVLAAA-------GLLDGRAVTTHWRSADRL----------------------------------------------------------------------- +-----MVLLG------Y------PGVQALDLVGPFEVFSTDGYEIIIASPDGSPASTWNGLQ----------------------IVAQPLP--HH--PVDTVLVPGGAG-IEDLRRNPDVIDWLRRAAKTARRVVSVCTGAFLVAEA-------GLLDGCRATTHWAFADRL----------------------------------------------------------------------- +-MARKVVTVG------F------PGVQPLDVVGPFEVFAGGGYDVALASIDERPVATGIGLE----------------------FMTTRLPDPSA--PVDTVVLPGGGG-VDAARDNVALMDWVKAAAGTARRVVTVCTGTFLAAEA-------GLLDGCRATTHWAFADRL----------------------------------------------------------------------- +-MARTVVIAG------F------PGVQALDLVGPYEVFTGGGYDVIVAANGGQPIATAGGLA----------------------LGAVPLPDPRG--EVDTVVLPGGFG-VEAARADAQLLEWIRAVARRARRVVTVCTGAFLAAEA-------GLLDGHRATTHWAFAEQL----------------------------------------------------------------------- +-MVRKVVIVG------F------PGVQALDVVGPYDVFTGGGYDVVLASVQGRPITTPSGLA----------------------FVGAPLPDPDD--QIDTVVLPGGGG-VDAARQDADLVAWIKAAAGHARRVVTVCTGAFLAAEA-------GLLDGCRATTHWAFAERL----------------------------------------------------------------------- +-MSQVVGFFI------Y------DEFQTVDLAGPLDAFATEAYKLMTLSADALPVRSESGLQ----------------------TLADDTIAE--CDALDMLVIIGGRG-CQKVIHNPSVMAHLQRVAASSKRIVSICTGAFIVAAL-------FPERTLTLSTHWNFTEQL----------------------------------------------------------------------- +-MSQVVGFFI------Y------DEFQTVDLAGPLDAFSTEAYKLVTIAKDMTPIRAESGLK----------------------TLADDTIIN--CQALDVLVIIGGRG-CQKVINNQAVMTQLRRLAHSAKRIVSICTGAFIVAAL-------WPERVLTLATHWDFSQRL----------------------------------------------------------------------- +LPRRTVLILA------F------DGVQIIDIAGPAQVLSTPPYEVRIVALQAGLIENASGFC----------------------ILAGE--IPK-EGAVDTLVVPGGPG-VHNLRENPLASIALNDLSQRAARVCSVCTGAFLLAEA-------GILDGRRAVTHWRSSERL----------------------------------------------------------------------- +EQHRHIDALV------Y------HGINLLDLAGPMQAFWTPNYKLRILSADGQPIETQPGIK----------------------IAVDGTFAD--WNPDADLLIPGGR--IDKELGSGPLRPLLKEARTNGERIISICSGALILADS-------GILEGKQASTHWSRASTA----------------------------------------------------------------------- +MPAHRIVVPL------F------DGIQPLDVTGPYEVFMGPGYRVVLVGADGAPVRAESGMR----------------------LLADEQLP-A-PGRVDTLLVPGGRG-ARTTPADDALVTWIRAAAPRAERVLSVCTGAFLLARA-------GLLAGHTVTTHWRYARAL----------------------------------------------------------------------- +-----MLVAL------T------PGYQPLDVVGPHEVFSVSGYSTRLAAAEVGPVRADSGLG----------------------LVATECLP-E-RGPIGTLLVPGGFG-VRRAARDPEFVAWLQRAAPRAERVVSVCTGAFPLAAA-------GLLDGLAATTHWRWAGQL----------------------------------------------------------------------- +-MTRSVVILG------F------PGVQALDLVGPYEVFSTPGYDVSLVSSNGTPIATGSGME----------------------LVTRPLPDPGA--GCDTLVLPGGVG-VPAVQRDPAVMEWIRASARCARRVVSVCNGAFLAAEA-------GLLDGCRATTHWAIAETL----------------------------------------------------------------------- +----MVVIVV------F------DEVTMLDVAGAAEVFVEADYLVKIASVDGRDVTTSIGAR----------------------LGVTDSIAA--IGSADTVLVAGGDQ-LPRRPIDPALVEAVRSVAGRTRRLASICTGSFILAQA-------GMLSGRRATTHWHDARLF----------------------------------------------------------------------- +----MVVIVV------F------DGVTLLDVAGPAEVFVEANYRIEIASVDGRDVTTSIGTD----------------------LAVTQRISS--IESADTIMVAGGDN-LVGQPIEPALVEAVRSVPKRTRRLASICTGSFILAQA-------GLLSGRRATTHWRDARLF----------------------------------------------------------------------- +ARSKVVVIVV------F------DGVTLLDVAGAGEVFVEADYQLKIASLDGNDVTSSIGTR----------------------LGVTDSLSA--IGSADTVMVAGSDN-LPRQAIDPALVGAVRSLGARTRRLASICTGSFILAQA-------GLLSGRRATTHWHETRRL----------------------------------------------------------------------- +VGPRVVVIVV------F------DDVTMLDVAGAAEVFVEADYRVRFASVDGRDVATSIGAR----------------------LGVTDRIAA--VDSADTVMVAGSDL-LPRRAIDPQLVDAVRSVASRTRRLASICTGSFILAQA-------GMLSGRRATTHWHDAPLL----------------------------------------------------------------------- +KHSRVVVIVV------F------DGVTLLDVAGAGEVFVEADYRLKIASVDGRDVTSSIGTR----------------------LGVTDCLSA--IDSADIVLVAGSDH-LPGRPIDPALVEAVRSVAARTGRMASICTGSFILAQA-------GLLDGRRATTHWHDARLL----------------------------------------------------------------------- +PASPVVALLV------Y------PGFQAIDLAGPVQAFVTPAYDVRIVSTMGGPVKGTGPLA----------------------VLTEP--WSELSLPVDTLMVPGGPG-VDTACDEPALRHALTALAASARRVCSVCTGAFLLASS-------GLLEGRAACTHWRAADRL----------------------------------------------------------------------- +AHSRVVVIIV------F------DDVTLLDVAGAAEVFAEGDYHIKIASVDGRDVTTSIGTR----------------------LGVTDSISS--IESADTVLVAGSDH-LPARAIDPTLVAAVKSVADRTRRLGSICTGSFILAQA-------GLLSGRRATTHWRGTRSL----------------------------------------------------------------------- +--MRVVVIVV------F------DDVTMMDVAGAGEVFAEGEYSIKIASVDGSDVMTSIGVR----------------------LGVTDSIAS--VESADTVLVAGSDN-IPARPIDPALVEAVRSLAGRTRRLGSICTGSFILAQA-------GLLGGRRATTHWRNIRSL----------------------------------------------------------------------- +AGPRVIVFIV------F------DGVTLLDVAGAGEVFAEADYRIKIASVDGRDVTTSIGIP----------------------LGVTDIAAS--IESADTVLVAGSDN-LPTRAIDPALVEAVKAVAGRTRRLGSICTGSFILAQA-------GLLSGRRATTHWRNVRAF----------------------------------------------------------------------- +KEEKHIVILV------P------SNSALMDMAGPMEVFSRLQYIVHTSGEATRQIVTSSFLP----------------------ILCESTFEEINY-PIDTLILSGIPA-DDDQPLHPNLLPWIGAQANRVRRIGSVCSGSFMLAQA-------GVLNGKRATTHWRLCQKM----------------------------------------------------------------------- +PMTRSVVVLG------F------AGVQPLDITGPLDVFTASGYEISLVSVGGRPVSSGVGLD----------------------FVAHPLPAPDT--PIDTLVLPGGMG-VFEARYCSEMMTWIRATARRARRVVTVCSGAFLAAEI-------GLLDGHRATTHWASAQLL----------------------------------------------------------------------- +MEARTVLIVL------F------DGVLSLDFTGPLEVFAGGAYDIRTGSLDGSPVRTSSGLS----------------------VTPDLALPD--APAPHTLIVPGGEG-TRAM--DPGVVAWLRENAPAARRLVSVCTGAYALAAA-------GLLDGRRVTTHWALSEGL----------------------------------------------------------------------- +QTPRAIACTI------Y------PDVQVLDVTGPLQVFASAGYSLHLLADAVGPVACSAGFS----------------------LLAEAAREDEDPARFDTVLVPGGWG-AEDQLNNEALLAWLQRAEPRVRRLGSVCSGALILAQA-------GLLDGRLATTHWDSVEAL----------------------------------------------------------------------- +--------MV------F------ENVNLLDISGPVQAFHSPLYTHRFLSLDGKSITTSCGMV----------------------VLPHGKITD--LTPHSDLLIPGGIG-VDQLLENETLLKLLREFGNKDRRLISICSGALILAAS-------GVLDGREATTHWSREQMA----------------------------------------------------------------------- +LVPRQVVIAG------F------PGVQALDVVGPHDVFSGGGYQVVLASVDGQPVTTPAGLG----------------------FVATALPDPGR--PIDTVVLPGGAG-VDAARGDAELIAWIKAVAGRARRMVTVCTGAFLAAEA-------GLLDGHRVTTHWAFADRL----------------------------------------------------------------------- +-MARKVLIVG------F------SGVQALDVVGPFEVFAGGGYDVTLVSPGGHPVTTATGLA----------------------LITEPLPDPRA--AVHTVVLPGGAG-IDAARDNPELMAWIKAVAPLTRRLVTVCTGAFLAAQA-------GLLDGRRATTHWAFADRL----------------------------------------------------------------------- +FMPRKVVIAG------Y------PGVQALDVIGPHDVFTTGSYDVTVASVDGQPVSTATGLA----------------------FVAAPFPDPGD--SIDTVVLPGGGG-IDAARADAELVAWVKAVAGHARRMVTVCTGAFLAAQA-------GLLDGQRVTTHWAFAERL----------------------------------------------------------------------- +LVPRQVVIVG------F------PGVQALDVVGPHDVFSGGGYQVVLASVDGQPVTTPAGLG----------------------FVATALPNPGR--PIDTVVLPGGAG-VDAARGDAELIAWIKAVAGRARRMVTVCTGAFLAAEA-------GLLDGHRVTTHWAFADRL----------------------------------------------------------------------- +PMVRTVVIVG------F------AGVQALDVVGPFDVFTGDGYDVRVVAVDGAPVSTGTGLT----------------------LAADPLPGPDE--AVDTVVLPGGWG-ADTARRDQVLIDWITAAAARARRVVSVCNGAVLAAQA-------GLLDGCVATTHWAYAPQL----------------------------------------------------------------------- +-MTRSVVILG------F------DGVQALDIAGPFDVFTGDRYDVRLVSLDGSPVRTMTGLE----------------------FGAAALPETA---AIDTLIVPGGFG-TETVRKDAATVQWIRAVAETARRVVTVCSGAFLAAEA-------GLLDGCRATTHWAAAGHL----------------------------------------------------------------------- +-MVRTVLIVG------F------AGVQALDIVGPFEVFTGDGYTVRVVSVDGTPVSTGTGLT----------------------LVADPLPDPGE--PVDTVVLPGGMG-TEAARTNAGLVEWITAVASRARRVVSVCTGSSLAAQA-------GLLDGCIATTHWAFAPQM----------------------------------------------------------------------- +DMARQVLILG------F------EGVQALDMVGPFEVFTGDGYDVRVVSAHGVPVSTGTGLT----------------------LVADPLPDPAG--PVDTVVLPGGYG-TETARKDPDLIDWISAVAPHARRVVSVCTGAVLAAQA-------GLLDGCVATTHWAFAPQL----------------------------------------------------------------------- +-MTKAVIVLA------Y------PGVQPLDVVGPFDALAAADYDIRLVASTTPPVRSNTGLC----------------------FATEPLPDPTA--RIDTVVIPGGPG-AETARGSTEIVDWIRAVHQHARRVVSVCTGAFLLAQA-------GLLDGCRATTHWGSAARL----------------------------------------------------------------------- +RKTRTVAVVG------F------DGVQSLDVVGPMEVFAVAPYEVVLASTDGHEIATHAGFR----------------------LAGAIALADLPA-ELDTIIIAGGSEDLRSAACEDGVLPWLRERSTQTRRIASVCTGAFVLAAA-------GFLDNRRATTHWNACELL----------------------------------------------------------------------- +-------MIG------F------DGVQSLDIVGPMEVFAVMPYRITLASHTGGEITTHAGLR----------------------LAGAVALDDLPD-ELDTIVIAGGSEALRHAASEDGVLPWLRARVPRTPRIASVCTGAFVLAAG-------GFLDGRRATTHWNACALL----------------------------------------------------------------------- +TRPRKIAIVG------Y------RGAQSLDINGPFEVFAMTVYEPILASPHGGAIVCNSGLG----------------------IAGSVAFADLPT-DLDTILVAGGDEELLG-MRDANVLEWLTERARSTRRVGSVCSGAFVLAAA-------GMLDGRRATTHWEVCDEM----------------------------------------------------------------------- +SSVREIVVIG------F------DGVQTLDVVGPMEVFAVPPYRITLASQTGGEIATHAGLQ----------------------LAGAVALDAVAQ-RVDTILVGGGSERLREAASEAGVLPWLRSRARGTRRIASICTGAFVLAAA-------GFLDGRRATTHWNACDLL----------------------------------------------------------------------- +-----MVLIG------F------DGFQALDLVGPMEVFSKFRYGLAIASASGDTIVSNSGLQ----------------------ISGAVPLGKLAD-DLDTIMVSGGSVELGDSPEGRSLLLWLKTHARNARRVASVCTGAFVLGAA-------GLLEGRRATTHWANCGRL----------------------------------------------------------------------- +PACTEVVFIA------F------DGVQMLDVAGPMEVFAVAPYRLTLCSPTGQPLATHAGLQ----------------------LGPVVALQDAPP-GIDTLVVTGGSEQLLAAASHPALRDWMQARAPAARRVVGVCTGALVLAAA-------GLLDGRRATTHWNRCELL----------------------------------------------------------------------- +LPPLTFACLI------Y------PGFMSLDVVGPWQVMASPHYALRLLAEQPGMVTCSAGLG----------------------LVAQAAYGDEPIAGIHTLIVPGGQG-VSGQLGNATLLRWLQQAEPLVARMGSVCSGALLLAEA-------GLLHGRPATTHWERVAEF----------------------------------------------------------------------- +SAVRIVASLL------Y------PDVMSLDVTGPLQVFASPAYQISLLANQPGPIMTSSGIQ----------------------IVADQSWRDMPAEQLDTLLIPGGIG-VEQQCRHTELLDWLQQSQPRLRRLGSVCSGALILAEA-------GLLKGRRATTHWADLEAL----------------------------------------------------------------------- +DDMKAVAVVG------F------SGVQALDVVGPFETFTCEGYEVMLASVDGQPVPASTGLG----------------------LMACPLPDPEQ---VDTVVIPGGVG-VRQAAADPALMTWFREAAEHARRIVSVCTGAFLVAEA-------GLLNGCQATTHWAFADEL----------------------------------------------------------------------- +--MKAVTVVG------F------RGVQALDIVGPFETFTSTGYEVALASVGGEPVAASTGLV----------------------LSARPLPEPDQ---VDTVVIPGGVG-ISR-NSDPALIEWVKETARHARRIVSVCTGAFLLAEA-------GLLDGRQATTHWAFAERL----------------------------------------------------------------------- +SQPRRIVLAV------F------DGVESLDVTGPAQVFSARGYTVELVGAGPAPVHCAGGVR----------------------LLADSAFADSDGEGVDTLVVPGGLRIGVEAVVDPEVLTWVARVAPRVRRVVSVCAGAHTLAAA-------GLLAGRRATTHWATAEAL----------------------------------------------------------------------- +VSMKVIACLV------Y------PGVMSLDVTGPMQVFASPFYDLQLLGETPGPVATSAGLK----------------------LHADASWQSVDCATLDTVLLPGGSS-DAEQCANTALLAWLRAAAPQVRRLGSVCSGALMLASA-------GLLDGLIATTHWDDVEAL----------------------------------------------------------------------- +DVMRSVVILG------Y------AGVQALDLAGPFDVFSTEGYALTLTAVDGQPVSTLTGLE----------------------FVAAPLPDPGE--PIDTIVIPGGIG-ADAARGNAAVVGWISTAAKHARRVVSVCTGAFLAAQA-------GLLDGCPATTHWSSARRM----------------------------------------------------------------------- +-----MVILG------Y------SGVQALDLAGPFDVFTADGYVVTLTSADSEPVTTLTGLE----------------------FVAQPLPDPAD--AIDTLLIPGGIG-ADTARAKPEVIDWIKTAS--ARRVVTVCTGAFLAAQA-------GLLDGCPATTHWASAGRL----------------------------------------------------------------------- +-----MVLLG------F------RGVQALDVVGPFDVFTLEGYAPVLTSADGGPVSTLTGLE----------------------FVAKPPPDPSQ--PIDTVVLPGGMG-VDQARGNPAVMDWIRTAAPHARRIVSVCNGAFLAAEA-------GLLDGCSATTHWASADQL----------------------------------------------------------------------- +-----MVILG------Y------PGVQALDVAGPFDVLSGEGYAITLVSADGGPVAAGDGLQ----------------------FVAQPLPDVGE--PIDTIVIPGGYG-TDDVRGSAEVIEWLQRASVDARRVVTVCTGAFIAAQA-------GLLDGCSATTHWAWAGRL----------------------------------------------------------------------- +VVTRSVVILG------Y------SGVQALDLVGPFDVFTGQAYTVTLASADGAPVTTLTGLE----------------------FVAAPPPDPCG--DIDTVVIPGGIG-ADEARRNREVVNWIKTAADHARRVVTVCTGAFLAAEA-------GLLDGCPATTHWASARRL----------------------------------------------------------------------- +GFMRAVVVVG------Y------PGVQALDLVGPFEVFTGEGYKVSVVSRGGEPVTTLTGLA----------------------LFAEPLPDPRE--PIDTLVLPGGIG-VDDARQNPDTLGWIKIAAEHSRRVVSVCTGAFLAAQA-------GLIDGCIATTHWAFAAQM----------------------------------------------------------------------- +--MHRVVVVA------F------PGVQSLDVAGPAEVFAGAGYHVTIASLDGGVVTTESAVR----------------------LDTESFAS-I-LEPIDTLVVAGGFA-VWRHRSDPRFVAALDDLIARSTRLVTVCTGATLAAVT-------GALDGHRVTTHWARANRL----------------------------------------------------------------------- +LMTRTVLVLG------F------PWVQSLDVTGPADVFTTVTYDLRLVSQHGQPIDTGVGLQ----------------------FGAHPLPDPAE--PVDTLLLPGGTG-VHRAVDDADLIEWIRVAATRARRVISVCNGAFLAAEA-------GLLDGRRAATHWAMAEHL----------------------------------------------------------------------- +FMSRSVVILG------F------PGVQALDVTGPADVFTTVTYDLRLVSKSGLSVGTGVGLE----------------------FVAHTLPDPAD--PLDILILPGGTG-VHDAARDPELIDWIRRAAHRARRVVSVCNGAFLAAEA-------GLLDGKRATTHWAVAGLL----------------------------------------------------------------------- +VEQHRIVFVI------F------EGFQPLDLFGPYEVFQHGRYSCQVTAPYPGPVRSGSGLP----------------------VHVPHAVADLDPAGIDTLVVAGGGG-VDQARHDPVLTGWIADAGAGARRVASVCSGVFLLAAA-------GLLHGRRATTHWAREQQL----------------------------------------------------------------------- +--MRRVVFVI------F------DGFELLDLAGPSSVMAHDGYTSEVVASAAGPVRSSSGIA----------------------VDAVFGIGGLACDGIDTLVVVGGGG-VDAACHDTELVAWIAAAGASARRVTSVCSGVLLLAAA-------GLLTGRRVTTHWGREQQV----------------------------------------------------------------------- +-MTRHVVFVI------Y------EGFQSLDLAGPLEVFQHGGHSCRIVAPRPGPVRSSSGLP----------------------VHAAHGVADLDPGGIDTLVVAGGQG-VDRARHDPELIGWIAAAAAGARRITSVCSGVFLLAAA-------GLVDGLRVTTHWGRAEQL----------------------------------------------------------------------- +MSERRIVFVI------F------DGFQPLDLVGPHEVFQYGDYTCEVVAPRAGGVRSNSGLL----------------------VHAGHSVADLDPGGVDTLVVAGGQG-VDHAREDTALVGWIAGAAAGARRVASVCSGVFLLAAA-------GLLKGRRVTTHWSREAQL----------------------------------------------------------------------- +MEQRRIVFVI------F------EGFQSLDLFGPYEVFQHGGYSCRITAPRPGTVRSGSGLS----------------------VHVPHGVADVDPTGIDTVVVAGGVG-VDQARQDPALTRWIADAGAGARRITSVCSGVFLLAAA-------GLLQGRRVTTHWAREQQL----------------------------------------------------------------------- +MQQRRIVFVI------F------DGFQSLDLVGPHEVFQYGGYDCQVLAPTAGLVHSTSGLP----------------------VHAEHGVADLDPHGIDTLVAVGGNS-VDHAVHDSALTGWIAAAGASARRVTSVCSGVFLLAAA-------GLVEGRRVTTHWSREEQL----------------------------------------------------------------------- +MQRRRVGFVI------F------EGFQSLDLVGPYEVFQQHGYDVVVLATRAGPVQSRSGLS----------------------VHASHGVADVPPHEVDTIVVAGGRG-VDQAIGDTALTGWLTAAAAHARRVASVCSGAFLLAEI-------GLLDGRRATTHWGRAREL----------------------------------------------------------------------- +--MRRVVFVV------F------EGFQAVDLVGPHAVFHYGGYDCRVVAPQAGPVRSSSGLP----------------------MLAEHGIGDLAPEGLDTLVVVGGAG-VAEARRDPGLVAWIAAAAAGARRVASVCSGALLLAAT-------GALAGRRVTTHWARARQL----------------------------------------------------------------------- +MQQRRVVFVI------F------EGFQSLDLSGPFEVFQQPGYDCRIVAPVAGPVRSNSGLR----------------------VHADHGIADLAPAGIDTLVVAGGDG-VDHAAKDPALVGWVAEAAATARRVTSVCSGVFLLAAT-------GLLAGRRVTSHWSRDGQL----------------------------------------------------------------------- +VTDRRIVFVV------F------DGFQPLDLTGPHEVFHS-GYACEVVGPRAGPVRSASGLV----------------------MEAAHGVDARDPAGTDTLVVVGGHG-VDRARRDAELVAWIAAAAAGARRVASVCSGVFLLAAA-------GLLDARRVTTHWAREEQL----------------------------------------------------------------------- +PLPHHVVIAV------F------PGVDLLDVTGPAEVFALGCYRVRLAGPVAGPVRTSAGVR----------------------LVTDVAFDQVDG-PIDTLLVPGAAVMVPTVLVDPDVVAWVRAVAPRARRVASLCVGAHLLAAA-------GLLDGKTATTHWATAAQL----------------------------------------------------------------------- +PHSHRVVIAV------F------PEVDLLDVTGPAEVFALAGYEVRLAAPAAGPVTTSAGVR----------------------VLPDLTFDEVGG-RVDTLLVPGAVEMGPLARIDSDVVAWLQATAPHAARVASVCVGAHLLAAA-------GLLDGKTATTHWSTAAQL----------------------------------------------------------------------- +-----------------------YGSEEIEFVTPYDVLTRAGFEVKSAGVSLKKAFAHMSRNIRIV----------PDYTE---L--PSVPAQTAHEYFNILVLPGGGPGSKAFCESDEVLELIKNFQDAGKWFATICAATTALVASTK----KFKGEKKRVTSHPSVSE-------------------EIKVAGWQYS------EDRLVVDGKVITSRGPGTAMLFALTIVEV--------- +------------------------GAEEMEAVITADVLRRGGVDVTVAGLAGSPVKCSRKTV----------------------IAPDCALDDVLSKKFDIVILPGGQPGSNTLAASSVVGQVLKAHHDAGKYVAAICAAPIALKSHG--------IPTTLITSHPSV-------------------RKQLEEGGYKYSE------DRVVVADRIVTSRGPGTAFEFALKLVEL--------- +--TRKVCVLVSSEVHFCSTKFAEAGVSLSSLLDMHRACRSCGYTLEFVTPSGAPPPVGGSLEEVLLE----KQREADAELLLQQLQHPQQLRKASAVDYCCLLLPHHLGAAIDLYSSANTGALIKEFGALKKPVGVLGYGAFALCAKPLSGSEALPLAGRLISTVPLAEEARHP----YFGLLPLHLELHFAAEGAQTAAG-LPGTEGLVIDGQLVSASSETSTELLLRV------------- +--TKKVCVLLSSEAQFFSTKFADAGVSLFSLLAMHRAAQSSGYTLEFVTFSGSPPPVAGTLEDLFLS----KEKEECADLLLQQLQRPQQLRKATAADYCCLLLPHHLGAAIDLYSSSNTGTLIKEFGALNKPVGAVGYGAFALCAKPLTESESFPLAGRLVSTVPLAEEARYP----YFGLLPFHLELHFAAEGARIAAG-PTGAPALVVDGQLVSTGNEASTEFLLKT------------- +--CRKVCVLASSEVHFCSTKFAEAGVSLASLLAMHRACRSCGYTLEFVTPSGSPPPVAGSLEEVLLS----KQREADAEMLLQQLQQTQQLRKATAADYCCLLLPHHLGAAIDLYNSTNTGALIKEFGALKKPVGVLGYGAFALCAKPLSGSEGFPLAGRLISTVPLAEEARHP----YFGLLPLHLELHFAAEGARTAAA-PGGSEGLVIDGQLVSASSETATELLLRV------------- +--ARKVCVLVSSEMHFCSTEFAEAGVSLASILAMHRASRSCGYTLEFVTPSGSPPPVAGHLEEVLLE----KHKEEDAELLMQQLQHPQQLRKAAAADYCCLLLPHHLGAAIDLYSSASTGALIKDFGALKKPVGVLGYGGFALCAKPLAGSEAFPLAGRLISTVPLAEEARHP----YFGLLPLHLELHFASEGARTAAG-LSETGGLVVDGNLVSASSETSTELLFRV------------- +--AGKVCVLVSSEVQFCSITFAEAGVSLGSLLAMHRACRSCGYTLEFVTPSGAPPPVAGSLEEVVLA----KQREADAELLLQQLQQPQQLRKAAAADYCCLLLPHHLGAAIDLYSSNNTGALIKDFGALKKPVGVLGYGAFALCAKPLSGSECFPLAGRLISTVPLAEEARHP----YFGLLPLHLELHFAAEGARAAAA-A--AGGLVIDGQLVSASSEASTELLLRV------------- +-----------------------NGSEEIEALNLIDVLRRAGANVTVASVEDTLQ-----IV----T---------RRHKF--NLIADMMLDEAAKMEFDLIVMPGGLSGAQKFASTDKLVDLLKKQAGSGKAYGAICASPAHVLEP------HGLLKGKKATAFPPMAHLL-------------------TDQ--SLC------ENRVVIDGNLITSRAPGTATEFALAIVEK--------- +--MKRIGVVLSGC-GVN------DGSEIQEAVLTLLAIDRTGLDAVCFATDKPQL---QVVNH--LSGEQRNVLVE---AARIARGQIQPLAAASAEDLDALIVPGGFGVAKNLSNDAELAQLVQALHLQRKPLGFICIAPALLPK------------------------------------------------------------------------------------------------- +--GKKVAVVLSGC-GVY------DGTEVHEASACLVHLSRAGAEVKMFAPDVEQM---HSINH--VSGEVRNVLVE---SARIGRGMVEPLALLNEADFDALVFPGGFGAAKNLSSNNEVEKTIKDFHSNKKPIRLTCIAPCAGC-------------------------------------------------------------------------------------------------- +--SKKFAVVLSGS-GVF------DGAEIHEATLTLYAIVKNGGTYEIFAPDIPQH---HVVNH--ITGEERNVLIE---AARIARGKIKPLSEFNEKDFDAIIFPGGFGAAKNLSSNKDVENSIKQMADAKKPIGALCISPVIL--------------------------------------------------------------------------------------------------- +--GKRVAVVLAGC-GVY------DGSEIHESSAVLVHLSREGAQAEVYAPDVDQM---HVVDH--VKGQPRNVLVE---SARIARGNIKDLAKLDVQGLDALIIPGGFGVAKNLSTSKEVEDVLKAFHAAKKPIGLCCISPVLAAK------------------------------------------------------------------------------------------------- +--MKKIAVILSGS-GVF------DGAEIHESVLALHAVEKAGATWHCFAPNVEQL---HVVNH--LTGEARNVLVE---AARIARGNIEDVAKLNVDGFDALLVPGGFGAAKNLTDNADVAAACRAFKDANKPAGYLCIAPVIIPM------------------------------------------------------------------------------------------------- +--AKRVAVILSGC-GVY------DGTEIHEASAVLVHLSRAGAEVQMFAPDGDQM---HVVNH--CVGKPRNILQE---SARIARGDVTDLAKLDVSAFDAAIIPGGFGVAKNLSDQPHLEKIIKDFHKAGKPLGMCCISPVLAAK------------------------------------------------------------------------------------------------- +--AKKVAVILAGC-GVY------DGSEIHESSAVYVHLSRAGAQTEFFAPNTDQM---HVVSH--TKGQPRNVLEE---SARIARGNIKDLKDLDVSEYDAVIIPGGFGVAKNLSTAKEVEAVIKGFHGAKKPIGLCCISPVLAAK------------------------------------------------------------------------------------------------- +--MKTVGVVLSGC-GVL------DGAEIHESVLTMLALDRAGAEVLFFAPDKPQL---HVINH--ITGEIRNVLVE---SARIARGLITPLSAADPEVLDALIVPGGFGAAKNLCDEPDLYKLIQLMHKSGKPIGLMCISPVMLPK------------------------------------------------------------------------------------------------- +-----------------------AGTEPVEAAATADVLNRAGARVTVATADGGRGL---LVEA----------------AFGVKLVADGRVADLEGEAFDLIALPGGMPGSANLRDCKVLEKMVKKQAEQGALYAAICAAPAVTLAH------WGLLKGLKATCYPSFMEKFT----------------------AEII----PVDSRVVVDRNAVTSQGPATAIEYALALVE---------- +-----------------------------------------------------------------------------------WTKPNETFSTCP-D-VDVLAVPMLPP---EIQNDPEVVNFVADKAKDAKYVIGICNGVVLLGAA-------GLLKGKRVTSS-------------------YNSLSIVESLGASEVVR---EGGGTVVDGNLYTAGP----------------------- +-----------------------------------------------------------------------------------PTVPTATFDTCP-E-LDVFAVGMNPP---EVQNDPAVIAFTRQAAGQARYVIGVCNGVALLGAA-------GLIEGRTVASN-------------------FAAEELLLKLGAGKILS---SGSGAAVDGSLYTAGP----------------------- +-----------------------------------------------------------------------------------PTVPTTTFATCP-D-LDVFAVGMNPP---EVQNDPEVIAFTRKAAEGARYVIGVCSGVALLGAA-------GLIEGKTVASN-------------------FAAEDLLRDLGAETVLA---SGTGPAVDGNLYTAGP----------------------- +-----------------------------------------------------------------------------------WTKPSTTFSDCP-ESLDVLAVGMHPP---EVQNDLEVIDFIRDLARRSRYVVGVCNGVALLGAA-------GLIHGKTVASN-------------------FAAEALLHDLGASAVLP---SGGGVAVDGNLFTAGP----------------------- +-----------------------------------------------------------------------------------ALTAYRSFADID-S-TDILYVPGGPG---VAMSDQDVLDTIRRLAVSAKWTVGICNGVELLGAA-------GLLYGKQVTTN-------------------WAVRDRVADYGANVS------TNRFIRDGQLITGAG----------------------- +-----------------------------------------------------------------------------------PTMPTMTFDECP-EDLDVLVVGMVPP---EIVEDEETLTFFANMGNKARYVIGTCYGSLVLGAA-------GLLKGKKATSN-------------------SNVVPMLPDMGAIAV-----EGSDVVIDGNIYTSGP----------------------- +-----------------------------------------------------------------------------------TTRATTTFAECP-KALDVLHVPAIPP---RVMEDKESLAFLAEYGGRAAWLSGVCAGALMLGAA-------GLLKGYRATTN-------------------FHLHDQLPYYGAIPT-----Q-GNVVEDRNRLTSGP----------------------- +-----------------------------------------------------------------------------------PMHATTTFAECP-SDLDVLCIGASTG---I--LSDEALEFLVDRGNKAKYLIGICGGSLMLAAV-------GLLKGYRATAT-------------------FSLVEELRHFGAIPV-----TGGEVVADRNRITASP----------------------- +-----------------------------------------------------------------------------------PTRATTTFEDCP-ADLDVLFAGAVPS---EIFEDEEVLAFLADRGSRAGWIAGVCVGSLLMGAA-------GLLRGYRATTN-------------------FQVHEHLAAFGAIPE-----R-GNVVEDRNRITSGP----------------------- +-----------------------------------------------------------------------------------PVHATTTFSESP-RDFDVLCVGACPD---EILRDEETLAFLKDRGSRAGYLVGVCSGSLILGAA-------GLLEGYRATSN-------------------FHVMDLLPHFGAIPT-----R-QNVVIDRNRYTSGP----------------------- +-----------------------------------------------------------------------------------PIAATTTFADCP-DDLDAFVVGAVPA---DVIADDDVIAFVRRQAGRARYVIGICGGVLLLGAA-------GLLNGRRATTN-------------------FHVLDALADLGARPV-----GGGEVVIDGNLYTAGP----------------------- +-----------------------------------------------------------------------------------PLAATTTFDECP-P-LDVLVMGAVPA---DMNRNPDILAFIARQSQHDPYLMAICGGALLLGAV-------GLLKGRKATTN-------------------FHLLESLPLFGAEAV-----PGGAVVQDGKLLTAGP----------------------- +-----------------------------------------------------------------------------------PIAATTTFADCP-DELDAFVVGAVPA---DVIADDEVIAFVRRQASRARYVIGICGGVLLLGAA-------GLLNGRRATTN-------------------FHVLDALAELGARPV-----GGGEVVIDGNLYTAGP----------------------- +-----------------------------------------------------------------------------------PCHASTTFDECP-PDLDVLVIGAVGT---AAIEDPQLIQFLREQCPRTRFVISICAGALLLGAA-------GFLEGRRATTN-------------------LHLTHTLEAFGATAV-----SGGEVVIDGPLYSAGP----------------------- +-------------------------------------LASAAFNLQVATPGGKTMDVDVSESN---ARWVQ-DFR------LKAYASPAKLESIDGARYHALLIPSCPGALADLASSGSLARILRHFHSESKPICAVGHGVAALCCATN-EDRSWVFRGYSVTGVSAARPVA----------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------------------QAFADSTALLALIDAFSQQGKLVAAICATPALVFAK------QQKFVGARMTCHPNFFDHIPS--------------------ERLSR------QRCYYATQHLLTSQGPGTALEFALAMIAL--------- +---------------------------------------------------------------------------------------------------------------TTLKESATLRSMVEKQAADGRLHAAICAAPAVALGS------WGLLKGLKATCYPSFMEQLSS--------------------SATVV------ESRVQQDGKVVTSRGAGTTMEYSVTLVEQ--------- +-MSKKVLVPLA------------NGFEEIEFVSIVDTLRRAQIEVLIAGVGDEEGADEGSADGALKTGECKDSANGRSYAHGIAISADATLDSLDLAGFDGVALAGGWQGMLNLKASQKLREILREFKAEGKLVSAICASPIVLDAA-------GVLEGK-FACYPSCEK------------------------------------------------------------------------- +------------------------GSEETEAVTTFDLLVRAGMQVRAASVNGDGGL---TIVGS---RGV-------------RLLADAPLAPLAEQPFDAIVLPSDMQGAECFQRSPLLLECVRRMHLDGKLVAAICAAPALVLQH------HQLFSQAYMTGFPALKDRI-----------P----------ADRWV------DQRVVHDYRLLTSQGPGTAMDFALNII----------- +------------------------GVTQLDLTGPWEVFSRPGAQVHLIWKTREIVQSDK------------------GM----GIQPTATFTDC--PQLDLICVPGGPG-QIPLMDDTETLQFLRERAQQARFITAVCTGALVLGAA-------GLLHGYQATTHWASLD-------------------QLALLGAIPL------AQRVVRDGNRITGAGVTSGIDFALSV------------ +------------------------DMQLLDLAGPYEIFSAPDCDIHLFWKTREPLACSA------------------GM----LFQPTTTLDDG--PLVDVLCIPGGVG-INPLLLDKEVQAWVQRQASAARFVSSVCTGALLLGAA-------GLLAGQRATTHWRYHD-------------------LLAEFGAIPV------RQRVVRDGNLITGGGVTAGMDFGLVL------------ +--TKTALVVLAN------------GAEDVEFVAAVDVLRRAGMKVLVASVGDSLVKTSHGL----------------------KIEGDILLKEVSQNNYDVIVIPGGLKGAENCRDSSHLAALLRAQHSSSKWIAAICASPALVLQQ------QGFLENVRAVAYPSFQQQ-------L----P------LK--G----------EGRVCVDKHFITSVGPGSAMEFALEIVKHL-------- +-----------------------PGAEEMEFTISADVLRRGKILVTVAGLHDEPVKCSRSVVIVP----------------------DTSLEEVTRGDYDVVVLPGGLAGNKALMNSSAVGEVLRCQESKGGLIAAICAAPTALAKH-------GIGKGKSITSHPDMKP------------------------------------------------------------------------- +-----------------------PGAEEMEFTISADVLRRAKINVTVAGLHGEPVKCSRSVVIVP----------------------DTSLEHVTRGDYDVLVLPGGLAGNKALMNSSAVGEVLRCQDSKGGLIAAICASPTALAKH-------GIGRGKSVTSHPDMRP------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------------VSECDIVIVPSILLAAGWRDRYPKLVTWAVRMHGRGARICSACSGLFLLAET-------GLFDGRDATVHFSYADAF-------------------SELEVAVHP-----ERVLVIREELVSSGASNTWHDLVLYL------------ +-----------------------------------------------------------------------------------------------EASPDAVVVCDMYTSIDVPGRYPREIAWLRKVHDKGALVTSVCSGSLLLAEG-------GMLDGREATAHWAYRDMF-------------------QRHQVSFRN-----ESILCLADGIVTAGGVSAWHDLTVYL------------ +-----------------------------------------------------------------------------------------------VDDTDIVITASMLFENEWVGQHPETVDWLQRMHGNGADLCSACAGALLLAET-------GLLDGLETTTHWAFAPTF-------------------RRNNIRLRV-----DELLIVNREFVMSGAASSWQDLILFL------------ +-----------------------------------------------------------------------------------------------IEETDYVLVPNVLVDTETIALDRRLLNWIAEMHRRGARLLAACGGSIVLAEA-------GLLEGQSATTHWMYAPLF-------------------RSQNVELKE-----ERILVQGHSIVCAGGASSWQDLTLFL------------ +-----------------------------------------------------------------------------------------------IDKSNYVILAPLGRIN--LKFEPSLIAWLKEHYERGSRLISLCTGAFLLAET-------GLLDGKTATTHWQYDDVF-------------------IKKNVLLQS-----NEVICQQGRLSSSGGANAYQDLILNM------------ +-----------------------------------------------------------------------------------------------W-RGDLLVCAP-----RTLASERDAIAWLAERP--SARVASVCTGAFFLAEA-------GLLARRRATTNPLYARAF-------------------AARDVELEL-----SRVIVDEGEIVTAGTVSAALSLALYV------------ +------------------------------------------------------------------------------------------------AGADLVVVPSMWTQG--IEHNPRLVEAL-RDLPEHVLVVAMCSGAYMLAAT-------GRLAGKRATTHWLLAEGL-------------------QAREIQIDA-----ADNLVQEGGLCSGGS-LAGVD-ACLY------------ +-----------------------------------------------------------------------------------------------DVVYDIVYVPVIFGDLPL-LADEEIIGWLARQGEKGACLCSVCAGAFLIAQT-------GRLKGRKATTHWNLADSF-------------------AECDILLKR-----EKMLIDEGDCITAGGVSAYLDLSLYL------------ +-----------------------------------------------------------------------------------------------QEQFDLVFIPSAHYASQLLARQSAACDWLVSQWNAGAYLAANCTGTFVLANT-------GLLDGRPATTTWWLADQF-------------------RRRRVDLQL-----EPVVTEADRLICAGASASYLLQTIHV------------ +-----------------------------------------------------------------------------------------------IEKTDFILVPGFLPPIFIGNAPRDLTDWLRKHHEKHVMIGSTCTGTFLLAEA-------GILDGRVATTNLKFSRYF-------------------KRLKVKLRP-----ERILTEDGGVLCSGATTSFWDLCIYL------------ +-----------------------------------------------------------------------------------------------ASDADIVVVPGLTLSPERLPEQHLCLAWLAERDLAKTRIVSACTGAVYLAEI-------GILDGIEATTHWAWEGLF-------------------QRFNVRLRI-----DRGLCFSRGPVTSGGTTGWQELATFL------------ +-----------------------------------------------------------------------------------------------VTECDLLLVPTIGDSIKVLTQNSELLPHLVRLANTKADIASNCSGAFFLAKA-------GLLDHKIATTHWGYANKF-------------------KVDLVDLQE-----NQFVTHSGNIFCAAGGSAFYDLGLLL------------ +-----------------------------------------------------------------------------------------------AAGADVILFAPIMPSTARMDTLRALIPWLRQQSAAGSCIATSCTGSFLLAEA-------GLLDGKVATTHWRAAQAF-------------------RERQVVLRE-----SELITEDGNLVCGGGAVSYIDLAIHL------------ +-----------------------------------------------------------------------------------------------RKRADAVLLTAPFFSNGRREQLNELSSALRRQRKAGAVLAAYCTANYLLAEA-------GLLDGRAATTHWARAADF-------------------GRRRVEVRA-----HELLIAQDGIISGGSVTSYLNLAVRL------------ +-----------------------------------------------------------------------------------------------PSSLAIAFVPSGPPANQTLAGQQPLIDWLRAVHEAGGLLASCCTGSFLLAAT-------GLLDGRLATTHWRGEEAF-------------------RALRVELRI-----DSLLVEGERLLCGGGAQSFSSTVLRL------------ +-----------------------------------------------------------------------------------------------VHDADVILIPAFAQVIPSVRNIAPILNWLQDCHRRRITIAAMCTGAFVLAAT-------GLLDDRQATTHWQFSKQF-------------------QRRKVRFQL-----NTMLTEQDGLICTGAVTAIFNLGLHL------------ +-----------------------------------------------------------------------------------------------VDAADVVILPGWRDA--GETVTPDIVGVLRAAGARGAIVAGLCLGAFGLAEA-------GLLQGRRATTHWAMAGAF-------------------AAREVRVDP-----GAIFVDEGPVLTSAGIASGLDCCLHL------------ +-----------------------------------------------------------------------------------------------AERADLLILPATGSAIRTLEGNAGLLPWLARR-Q--QQVASLCSSAFLLAAA-------GLLDGRQATTHWALAETF-------------------TRHRVNLRS-----DLLLTEDGPLFCSGGAQAGLDLCLHL------------ +-----------------------------------------------------------------------------------------------AESADLLLIPATGSALRTLQHNAALLAWLAQRPL-QQQLASLCSSACLLAAA-------GQLDGRRATTHWALAEQF-------------------RQRGVRLQI-----DELFTEDANRFCSGGAQAGLDLCLQL------------ +-----------------------------------------------------------------------------------------------IPRTDLVLIPGFLFTLDALPAFCAYGPWLREQHAQGAVVASMCTAAFMLGEA-------GLLNGTRATTHWAFAELF-------------------RRRHALLDE-----GQIICEDNRVVTSGGASAAMDLLLHL------------ +-----------------------------------------------------------------------------------------------KEVYDLIIIPAMR--FLVVAREQLLIKWLQRQYLQGAELASICVGAFLLAAT-------GLLSGKKATTNWLFADKF-------------------RSHEIEVQD-----DKVIVDQGRLYSCGGAFSFTSFMIYL------------ +-----------------------------------------------------------------------------------------------SERFDVVLVPA-AVGNAEH----AAATWLRGQHERGAKLAAVCAGVFLLAET-------GLLEGREATTHWGLAQRF-------------------AARRVSLKP-----ELLLVDLGDVLTAGGVTAYLDLSLHL------------ +-----------------------------------------------------------------------------------------------CEKVDLVIIPAIGPNV---RRCRLEIEWIKEMASRETRIASVCSGAFVLAST-------GLLDGRRATTHWLFAPLF-------------------RRMSVHLDV-----DRLVIDQGNFLTSGGSNAFYDLGLHV------------ +-------------------------------------------------------------------------------------------------PYDLIYVAPFAIGRARLEPLHAVSEWLAAAHDEGARLAASGSGVAVLARA-------GVLAGVVVPLPWWLERSM-------------------ARLHLTFDV-----DRKVQVHDGLL-AGAHVGEPALAVRI------------ +-----------------------------------------------------------------------------------------------IDETDLVILHSVWGD-PLLTQQAALYPKLRQWHSRGIPIMAAATGAFFLAQA-------GLLNDRMGTTHWHKQARF-------------------ARAKVNLMA-----DRFITATGELYCSAGLNAALEIIVFL------------ +-----------------------------------------------------------------------------------------------IEPSDILVIPSIAGDIKTLAQNPQLIDVLKNMNSQGTVIAGNCTGAFFMAEA-------GILDNRTATTHWAFVDMF-------------------RQRKVDLRP-----EQMLTASENVFCSGGGIAWLDLCLYL------------ +-----------------------------------------------------------------------------------------------AKIADIVLVTSLFAASNYLTAQQEAAAWLKGMSDAGALVASACSGTFLLAEA-------GIMDGREATTHWLLEAVF-------------------RRRRVRYHG-----ERMLLEYGNVICGGAFFAFTDILLKL------------ +-----------------------------------------------------------------------------------------------LEAGSIIVVPAMA--YKKLESLRELIHWLVKQYENNCIICSHCTGSFILAET-------GLLNGHSATTSWWLAEQF-------------------RQRDINLKA-----DQLVVDGGRLLTGGANGAEMLAALIM------------ +-----------------------------------------------------------------------------------------------PEQPDIWIIPGIYQSATAMRQSEVMIPVLQQHVADNKMIVCMCTGAFLLAQA-------DLLGKNPALMHWRNEHHF-------------------RRAHLSIDS-----QNTIAEYGNLCSIGGSMAYEYLVLRL------------ +-----------------------------------------------------------------------------------------------VVAPYAVVVPTIGADIQTLNNNHPMLAFLKWAKQNCQIISANCTGNFFLAEA-------GLLNGKQATTHWGFEDVF-------------------KRHNVDLRI-----DQLITQDDNIYCAGGGLAWFDMGLLM------------ +-----------------------------------------------------------------------------------------------LDHTDLVLVPGFLFSLEALPAFGRYSDWLRRQHRQGAVIASMCTATFMLAEA-------GLLDGVQATSHWAFADLM-------------------RRRAVRLDE-----RRILCEDGRLISSAGASAAMDLLLHL------------ +------------------------------------------------------------------------------------------------DSIDILLIPGFYAYNCVSQQLKPYTTELQAMLAQGKWLGAFCNGTFALAGT-------GLLNGLQATSVWFFKDYF-------------------RQMQVKLDL-----QQLVVQQQSILTGGATTSYLNLCLRF------------ +-----------------------------------------------------------------------------------------------L-KPDLIVVGSALEAVHSLDQARPLFGWLQSAAARGVTLASVCTGSFVLAEA-------GLLDGLAATTHWRAAALF-------------------RQRAVRLEV-----DQLLVDNGQVICAGGATAFSDLCLYL------------ +------------------------------------------------------------------------------------------------VDVDVLVLPSLAIPF--ARQPPGLSDWIAGQHRRGCLVLALTTGSWLLAET-------GLLDGHTATTHWACLERC-------------------RRQRVNWTS-----EQRLAVTGRLTARDM-SASATALCHA------------ +-----------------------------------------------------------------------------------------------VEKTDLIVIAS-ASYIEILGASPGLVPWLRRQYQGGAHLASICTGSFLLAET-------GLLDGKSATVHWGFADTF-------------------NARQVELRP-----DKMFIDHGRLYCSAGVNAGLDLSLYL------------ +-----------------------------------------------------------------------------------------------TGVPDLVLVGSSGIAGDA-DTDAAISGWLRAAYDGGAVIAGVCSGVFQLGRA-------GLLDGRRATTHWAFADEL-------------------RRMAADVRP-----ARMVLDEDRIVTAGGVNAASDLALHL------------ +------------------------------------------------------------------------------------------------S--DIIVIPAFWDDF--CQRYPQILPWLREQHANGAVLCAEATGVYWLAEA-------GLLDGKEATTYWRFFSAF-------------------AERKVLLNQ-----EKHLTDADNVYCAGGTTSACDLYIYL------------ +-----------------------------------------------------------------------------------------------PNAPTHVVFPPSLVPP-GMDSAHALRDWALERRGDGAVLCGLCAGVFVLAQT-------GLLDHRRATTHWAFAEEF-------------------AERAVRLDA-----RRMVVDEGEVITAAGIMAWLDFGLSL------------ +-----------------------------------------------------------------------------------------------APQIDTLIVAGG----AALEADEQACEWLRARSAQIRRLCSIGTGAFALAAA-------GLLDGRQVVTHWKFAAEL-------------------QVRAVHCQT-----EALYLHDGNLWTCGGATAGIDLALGL------------ +-----------------------------------------------------------------------------------------------PAVAHTVIIPGT----LSLDTASELKLWLAREGHRAERIGALCVGTLLLAEA-------GLLNGRPAVTHWSFAKSL-------------------QSTHIQVEE-----GRLFNRHGNAWTCAGVTAGIDLALAF------------ +-----------------------------------------------------------------------------------------------VERPDLVFVPAGGLPLSVIESNAGVVPWLRRWAAEGTKIAGVCSGVALLAEA-------GLLDGKRATTHWGLADVY-------------------RQRAVDWQP-----DYLITDAGDVFCGGGINSAADLSLYL------------ +-----------------------------------------------------------------------------------------------NPDADLLIPGGR----GSGTL--RPLLKEAAARTNGERIISICSGALILADS-------GILEGKQASTHWSRASTA-------------------QSEDVDWQL-----NQLFVNSGNIYTSAGVTAGIDLTLHL------------ +------------------------------------------------------------------------------------------------SQISFVIIPPSFEEPVSQQDAQIYVLWLKELYQRGVILCSICSGIFILLET-------GVLQGRTVTTHWSNITTL-------------------KTRHLKVDC-----NKMVVDENDIITTAGPMSWIDMGFTL------------ +-----------------------------------------------------------------------------------------------TDSADAIILPPNLTGV-G-DTDRHLHNWIQKQHLAGTIVCSACAGSFWLGHA-------GILDGRQATTHWALETEF-------------------RSAKVQLRA-----EHILLDDHDIVTAGGVMAWIDLGVHL------------ +-----------------------------------------------------------------------------------------------SCSINFIIVPPSFEAP-SQEGAQNYSQWIEQHYKNGAVLCSICSGIFTLLET-------KLFSGRTVTTHWLNNEIV-------------------NARDVVVDS-----NKIIVDDPDLITTAGIMSWMDLGLKL------------ +-----------------------------------------------------------------------------------------------ESIARVVIIPPRETAILGTELAPKWSDWLIGQHAGGATLTSICGGTFLLAQT-------GLLDGRRATTHACSVPNL-------------------TALAIEFDV-----DAVRTEDDDIITVGGIMAWTDLALVI------------ +-----------------------------------------------------------------------------------------------QAAPDVLIVPPCFDAL-VDWRQPALTTGLQALHEHGAIMASACAGSFALAGA-------GLLDGRKATTHWRLAKDF-------------------QAMLVELVE-----DELLVDQGDVVTAGGVSAWMDLGLRM------------ +-------------------------------------------------------------------------------------------------KYDVLIVPGFGLSRLKLGSRAKEIEFIRHAFAKGTRVASACVGAFLLAEA-------GLLDGRKAVTSWLFAGEL-------------------ARRAIVVQP-----EALLVEDSAVITTGAVSAANDLAIFL------------ +------------------------------------------------------------------------------------------------TTPSICILPPALGGPRD-DANPAVTRWLQERHADGAVLTSICSGAFVLGAT-------GLFDSRTVTTHWTYEDRF-------------------RAQRARIDT-----DRIVIDDGDIITAGGVMAWTDLCLTI------------ +------------------------------------------------------------------------------------------------HRADYVIVPPSIAMPEKMQSVPEAAKWLTHQHGRGSRICSVCAGAFVLAES-------GLIDGRQVTTHWAFAQEL-------------------ASKEVSVAD-----QHMVLDDGDIITAGGILAWTDLGLTL------------ +------------------------------------------------------------------------------------------------GEPSIIIVPPLRTVVESMEEDLAASAWLRDRHNAGVTVAATCGGVFLLAQS-------GLLDGRQATTHWACARQL-------------------AHSSIDVDA-----DQLIIDDGDLITGGGMLAWADLALIV------------ +------------------------------------------------------------------------------------------------NAPAFVISPPSVAMPERMSAMPREAQWLKELHAGGAIMCSVCAGAFVLAQT-------GLLARRRVTTHWAFAGLL-------------------ASADVQVTT-----ENVVIDDGDVITSGAILAWNDLGLLI------------ +------------------------------------------------------------------------------------------------VRLRVLIIPPSLHAIPDDACLARHRSALCRLHQQGTVLACVCIGVFFIAAC-------GLLNGRAACAHRTHVQIL-------------------AARYTRAEA-----QQALLDDGDIVSSAGLMAWTSLGLCL------------ +------------------------------------------------------------------------------------------------CTDSVVIIPPCLGH--TPKEFASWPHLLSPWHQKGTLICSICAGALYLAQT-------GLLDDRPATTHWSLEEEF-------------------LKREVKLNI-----DKLLIDDGDIITAGGLMAWVDLGLRL------------ +-----------------------------------------------------------------------------------------------SKRYDAVILPPSAGRV-L-EDVPVLPGFLQHLHGNGSVVCSACTGLTFVAAA-------GLGAGRKVTTHWGLEQRL-------------------SAADLRLDT-----DRLLIEYSDLITAGGLMAWVDLALAL------------ +------------------------------------------------------------------------------------------------RALVAVLIPPSITGFSEDKAPQGLIHWLRQQHASGATLGGVCVGSILLAES-------GLLDGRSATTHWTSAKAF-------------------AERAIRLKA-----DTPIVDDGDLITTAGLMAWSELGLRL------------ +-----------------------------------------------------------------------------------------------ADIPAVIAVPGQISQGVCLRADEVLLDWLRAHYDGGSLLAAASDGVSMLARA-------GLLAGRTVSGPDLGRHPG-------------------LQGASWVPS-----ERALVDDGDLLTVAGSQAWRFLALRL------------ +-----------------------------------------------------------------------------------------------ADIPAVIAVPGQISQGVCLRADEVLLDWLRAHYDGGSLLAAASDGVSMLARA-------GLLAGRTVSGPDLGQHPG-------------------LQGASWVPS-----ERALVDDGDLLTVAGPQAWRFLGLRL------------ +-----------------------------------------------------------------------------------------------EQVFDAIILPPSLGSDSESPSFNQLNLWLIDQHKQGAILSSACAGAFLLANT-------RLLDNRPVTTHWQLSQKL-------------------QAHKARIEG-----DKILINDKDIITAGGLMAWLDLGLEL------------ +------------------------------------------------------------------------------------------------RQADLLVLPSFYGDV----ASPALLRWVVRHYDAGGCILASASGVRILAET-------GLLDGRDATCNLADRRAI-------------------AATAVRLSP-----QSPLVVDGRL-TAASITPTIDACAHL------------ +-----------------------------------------------------------------------------------------------DHRPDVIIVCDIELPLGGPGRWRGEILWVREQVKRGAVVCSTCSGSVLLAEA-------GLLDGQNATSHWSASELF-------------------RDRAVKFRP-----ERILCDDGRLITTGGASSWQDLALYL------------ +-----------------------------------------------------------------------------------------------ADDAEIICLPNFRIGMTPPEVLRPEIDWIVERHSAGARLATACSGSALLADA-------GLLDGQEATAHWSMAEVF-------------------EKRRVAFCP-----DRTLTFGDCIVMSGGMASWQDLALYL------------ +--------------------------------------------------------------------------------------------------ADVVIVPDIAVGAFDPGSWPEECAWLRECFDQGAIICSVCTGSLVLAEA-------GLINGQQATCHWASVEQF-------------------KKFSVNLAP-----ERILSTADRIVTSGGASSWEDLALYL------------ +-----------------------------------------------------------------------------------------------NSKADILIIPEIWLGPETLGRYPQLMDFLRRKYDEGSYLYSACSGALLLAES-------GLLDGCCATSHWGYQDLF-------------------RRQNIKFQP-----APNLCFQGRIVTAGGTTSWHDLMIHI------------ +-----------------------------------------------------------------------------------------------VSSPEIIIIPPLILDLAPLESYGAIADWIKAAYEKGSVVASVCSGALLLART-------GLLDGEEATTHWGYCDAM-------------------ARRGIRIRK-----ERILVPGHRIITAGGGSSWYDLLLYL------------ +-----------------------------------------------------------------------------------------------SYTPEIVILPELWLGPEDMGRYPDLMKWICQQHAKGAFIYSACSGAIMLAST-------GLLDGCDATSHWGYQDLF-------------------RKRTIRFKP-----APNLTFSGQIVTAGGTTSWHDLAIFI------------ +-----------------------------------------------------------------------------------------------CPQPDIVCISDMLEAPADMTLYGPEIEWLRKAWQGGATLGSACSGALLLAQT-------GLLDGLEATSHWAFCDYL-------------------AKARTRWSP-----ERTLVVDQRLMMAGSGTSWYMLGLAL------------ +-----------------------------------------------------------------------------------------------ADAHEVVIVPAQFMPDQIGALERVFIDWLERRYAAGALVVGLNA-APLLAKA-------GLLDGRGATGLPSERTLF-------------------ARHAVRYTP-----SKPLVVDGRLITVSGINPAVDACAYV------------ +------------------------------------------------------------------------------------------------FDYDVLIIPGFWAWS--VAAN---KNLQEFLDPKKKSLYSYCTGSVFHAST-------QRLSKKSATASWWLAQEL-------------------VGAKVQWQF-----NQISAGDVSDMTAAGANGFYPLYSHL------------ +------------------------------------------------------------------------------------------------YQYDGILLPGFWGST--PITY---GRLINELKPTETKVWSYCTGVALHAES-------ERLNNTKATITWWLNEQA-------------------AVRKVKWNN-----HLACIYHAGDTTTSGANGYLHIFHNL------------ +------------------------------------------------------------------------------------------------RELDALLIPGFWAES--LSGN---AALIRALAGKRVQLWSYCTGVGLLAAS-------GRLNGQAATVTWWLADAM-------------------RDRRVRWQS-----ESSCVFDLGVATASGVNGYLPIAQGV------------ +------------------------------------------------------------------------------------------------FPCDVCLLPGFWAEK--LGRQ---AELIEALRPTGQALWSYCVGVALAAAA-------GALDGKAATGTWWFQHLL-------------------QRRRVRWRF-----PEPLVADRGAVTASGAQGYLPLMTQQ------------ +--------------------------------------------------------------------------------------------------VDAFVVPGLPSRQDLDRESGFVRPNLTQAAENGAIIAAHCSASWFLADA-------GMLDARSATTSWWLKHDV-------------------NMRRVRWDV-----SRLLVRDGLIYTCGGGFSGIELGKAL------------ +------------------------------------------------------------------------------------------------TSVDALLIPGFWTNH--IDAY---QPLISALKPAKTQVWGYCTAVCIMAAA-------GRLEHQQATATWWLADFV-------------------QNNTVDWSF-----SQTYTFESQNRTASGLNGYLPISQAL------------ +------------------------------------------------------------------------------------------------YQYDAILLPGFWGST--PITY---GRLINELKPSETQVWSYCTGVALHAES-------GRLNQTKATITWWLTDQA-------------------ASRKVKWNN-----HLACIYHPGDATTSGANGYLQIFHNL------------ +------------------------------------------------------------------------------------------------QPIDVLIIIGSQYQGQACQQLNSYAPLLSEKLSTPPTLVAGCCGVAYAAAL-------GLLDKQRITASWWLEAFF-------------------NRYQLELDT-----SPIYLCDQKLYTAGAAHSYIYVMLAL------------ +------------------------------------------------------------------------------------------------SEFDVVIWPGSQYRSQLCKSLKPFHPHIVKLAENAELVMSGCTAVPLLAHT-------GLLADKKITASWWLDSFF-------------------QRHGCKLDT-----SEMLRLDGKFLTCGATSSFLLLTWYL------------ +-----------------------------------------------------------------------------------------------EEQFDLVILPPMWGN-SAIHNTPGLTEWLIKQYQNGSQLMATGTSVVWLAET-------GLLNDQVATTHWYFYDKF-------------------SQRKIKLNR-----QASITAANGLYCTGSINSQTEMILYI------------ +-----------------------------------------------------------------------------------------------PVDFDLVFLPPMWGN-PSMAGREDILEWLRRQKENQAIIVATGTGVYWLAKA-------GLLEEKTVTTHWSFYGKF-------------------ELRTVGVNR-----KASITYCDNIYCVRSINSQTELLVYL------------ +-----------------------------------------------------------------------------------------------LPLYDYIIVPSIWRN-PIVRQNQALSESLADAWGAGSTLIGVGTGVCFLASS-------GLLDGHSATTHWHFAKQF-------------------SQLNVELKP-----DYFITQSERIYTVASLNALADVIVHI------------ +-----------------------------------------------------------------------------------------------APYSDLIIVPGIWRN-PVVSKHPRLVNWLADSWLQGSHIVGVGTGNCLVAEA-------GLLNGHPATTHWHYAEQF-------------------KRDNVQLKP-----DFFITQSERMYTVASLNALADVIVHI------------ +-----------------------------------------------------------------------------------------------TGICDLIFVPALWGN-AAVMQHSASVAWLTQQYAAGATVCSVGSGSYFPGAA-------GLLDGKPATTHWRYFDDF-------------------ESRRIKLQR-----KRFITHQDRLYCTGSVNAVRDVMLHF------------ +-----------------------------------------------------------------------------------------------DQHYDIVIISSRWRH-LGSPTDPKVKAWLKSLADAGSDICAVGNGSYFLGEA-------GLLDGRAATTHWHYFDDF-------------------AKRKAQLKR-----DYLITQAENIYCTGSVNAAADLIIHL------------ +-----------------------------------------------------------------------------------------------APTSHIVFIPGFWGN-AMLLKNAGVVAWLASQQ--PAIVCAITTGSYFIAEA-------GLLDDCDATTHWRFFDAF-------------------AKRRVNLQR-----NRFITRSANRYCTGSVDAVRDVMLHL------------ +-----------------------------------------------------------------------------------------------TGPGDLIIVPGLWRN-PVARQSKALVQWLKYQHQQGATFCVAATGVTFMAET-------GLLDHQPAATHWYFLERL-------------------KRNDVDFKP-----HHLITRSGRIFCAGSVNSVADLMVHL------------ +-----------------------------------------------------------------------------------------------LKFCDLLILPAIWRH-RVLRRAADWLPRVQELHARGSSICSVGTASALLAET-------GLLDGRPATTHWHDFDRF-------------------ERSLVDLKR-----RHLITQSERLYCVGSVNSIGDFMVHY------------ +-----------------------------------------------------------------------------------------------LGDIDLLYLPTLWRN-SVLHRQRRIIPLLQRLASHQALICAVGTGSCFLAEA-------GLLDGKPATTHWYFMDAF-------------------SRRGVELKR-----QHLITRAGNLYCAGSVNSVADLTCYF------------ +-----------------------------------------------------------------------------------------------CDHPDFIFIPPLWGN-PTIRTQQGLAQWIREMHQAGATVIATGTGVCLLAEC-------GLLNGKPATTHWFFFDRF-------------------RKLEVELNV-----HKFITYQDGIYCAGSINALTDLVIFL------------ +-----------------------------------------------------------------------------------------------PLDVDFVFCPPMWGS-QSFTRQRQAQNWLRAQYQQGSRLVATGSGVGMVAEA-------GLLDGRVATTHWYYLERF-------------------RQRSVNFQT-----EHFITHEDGIYCAGSINAQTDLVLYF------------ +-----------------------------------------------------------------------------------------------IADTDVIIIPALWRQ-KYLTDAKPLLDWLITRFQQGATIVAIGSGVWLPAKA-------GLLNGLPATAHWHSLAAF-------------------TAMKVKWQH-----DHLLTQAGRIFCAASINSGADLIIHL------------ +-----------------------------------------------------------------------------------------------DADYDIIYLPAIWRN-PIVRQNTAITRWLTMQAAKGTRIAAVGTGCCFLAEA-------RLLDAQPATTHWHYFEQF-------------------AHDEVNLKT-----KYFITQSENIFCAASVKALSDLTIHF------------ +-----------------------------------------------------------------------------------------------DFSSDLIHIPALWRN-PAVKKHQAYIPWLQQQHHHNCAITAVGTGVCFLAEA-------GLLDGKPATTHWHYFDQL-------------------QKHAVHLDR-----QHFTTQSGNIYCAASINAMAELIMYH------------ +-----------------------------------------------------------------------------------------------RFTSDLIHIPALWRN-PAVANNQAYIPWLQEQHQLNSSFTAVGTGVCFLAEA-------GLLDDKPATTHWHYFDQL-------------------QRSKVKLAR-----QHFTTQSGNVYCAASINAMAELIMHQ------------ +-----------------------------------------------------------------------------------------------KFKTDVVIIPPMNTDPILLKQNNVLIHWIKERYLEKVQLISLCTGAYFLAES-------GLLHHIPATSHWGAIEDL-------------------QKRKIDFKP-----DHVVTQSNAIITGGGGFSSLNAMLYF------------ +-----------------------------------------------------------------------------------------------VSLTNLVIIPGFKGEITILHKYRDVIHWIGEMHRCGAEIASMCVGSFFLAEA-------GLLNGKVATSHWAAAGEM-------------------QWRLVRVQS-----DRIITDQEGVYTSGGAFSALKLVLYI------------ +-----------------------------------------------------------------------------------------------VKAGDVLLVPGLSAASQLLADAARGITLLARVAAKGAMVAASCSATFVLAAS-------GLLAGRSATTTWWLVPSF-------------------VRREVALQP-----DRMVVESDGVLTAGSAFAHADLVLAI------------ +-----------------------------------------------------------------------------------------------FGTDDIVIVPGLGATTTRLVPVRRAMELLKAARQAGATLAASCASTFVLAEA-------GLLAGRRATTTWWLAPIF-------------------RRRDVTLLT-----EQIVVADWPVATAGAAMAQMDLMLAV------------ +-----------------------------------------------------------------------------------------------TPAPGLVVLPGLGLASAAMPAFATLSAALRHLAQPGTRIAGACTGVFALAAA-------GLLDGRRATTTWWLAPLL-------------------RAWKVRVEM-----GEVLYSDGALVTAGASFAQIDLMLHL------------ +-----------------------------------------------------------------------------------------------EGRGSVVVVCGPGMADEYVTANRELLDVVVVARGRGALISASCSSTFMLAEA-------GILDGLRATTSWWLGPAF-------------------RARAVTLVE-----DEMLIDVGTVLTAGAALAHTDLMIHV------------ +-----------------------------------------------------------------------------------------------ASDADIIIIPGFNHRNHFVNMPDGYLTWLKARHQAGKVLCGICSGTFVLAEA-------QLLDGRVATTSWWLTKAF-------------------RRRAVVLHP-----RDVVTEADNLICGGSATSWMHVGLRL------------ +-----------------------------------------------------------------------------------------------GPARPWVVVPGIGNASRRLADVQAAVEWLAKAID--SRVAASCTGTFVAAEA-------GALGGRTVTTTWWLAGLF-------------------AARDCHLDA-----DQMVVKDGPVLTAGAAMAHLDLLFAI------------ +------------------------------------------------------------------------------------------------VEPDMMIVPAVQVLDELVARSKPVLERIRQVYEHGSHVAGACSGTFFLAEA-------GVLDGSSATTSWWLGPTF-------------------RRRQIALDE-----SRILCRGPRVSTAGAALSHMYLALGL------------ +-----------------------------------------------------------------------------------------------DAVPEWIIVPGLGLTSARFRDARAAMDLLQAEAGRKVKIAASCSAVFLFGQA-------GVLNGHQVTMTWWLASLF-------------------RSRDVKLDE-----SKMLVRDRNCLTAGSAFAQLDLALAI------------ +-------------------------------------------------------------------------------------------------EFDVVVVPALGTLTDALRDARSVIASLGRLDEATTRIAAACTGVFAVAET-------GRMHHRRATTSWFLGPEF-------------------LKRTVALDL-----DTMVVADGNLVTAGAAFAHIDLVLSL------------ +-------------------------------------------------------------------------------------------------EFDVVVVPALGTLTDALRDARSVIASLGRLDDATTRIAAACTGVFAVAET-------GRMHHRRATTSWFLGPEF-------------------LKRTVALDL-----DTMVVVDGNLVTAGAAFAHIDLALSL------------ +-----------------------------------------------------------------------------------------------LAAADTVVLPPTHAM-HGGPLPPEVAAAI-AGIRPGTRLVSICTGSYVLAAA-------GLLDGRPATTHWNLAPEF-------------------RRARVKVDE-----DVLFVDDGDVLTSAGVAAGVDLCLHM------------ +-----------------------------------------------------------------------------------------------LAAADTVIVPPTHAM-RGGPLPAEVAAAI-AGIRPDTRLVSICTGSYVLAAA-------GLLDGRPATTHWNLAPEF-------------------RRVEVKLDE-----EVLFVDDGDVLTSAGVAAGVDLCLHM------------ +-----------------------------------------------------------------------------------------------LPAPDLVLLPGANRATDWLRDVLKAMERVGGWLEGGAAVGASCVSTFALAQV-------GLLDGRMATTSWWLAPWF-------------------RERRVDLDM-----ARMVVSDGPVSTAGAALAQADLMLAL------------ +-------------------------------------------------------------------------------------------------PPDLVIVPALGAKTAALKDVAEARRLLRAFAGQGVEIAAACTATFLLAGA-------GLLDGLPATTSWWLAPLF-------------------RARQVDLDE-----SRMIVETRRRMTAGAALGHLDLALRV------------ +-----------------------------------------------------------------------------------------------AISSDLIIVPGMMLSDIMPSEYKAVLKWLQNENIKKTIICGVCAGTFVLGDA-------GLLNRKNYATTWWLYHTF-------------------QKRHGKLSW-----GKTFEKDKNIITTGGPLSWIELVLYI------------ +-----------------------------------------------------------------------------------------------IEHCDAVLVPGFIPNGPKTTTDKLTCSWLATQYKKGALMCGSCSGVFALGEA-------GLLNNRKCTTTWWLHDEL-------------------KQRKANAVW-----ASELIDDNGIITAGGPLSWVTIALHI------------ +-----------------------------------------------------------------------------------------------LTHCDVALVTGMALGPPVSASISHAATWLQERHQAGALVGAACAGTFVLGEA-------GLLNGRRCTTTWWLHHAF-------------------RQRKACAVW-----GTAVEEQDRIVTTGGPLSWVDLALHV------------ +-----------------------------------------------------------------------------------------------TDAADTLVLPPISYRHTRLMAEQTAGALATRQHAAGRRVMSFCTGVPLLAEH-------GLLDGRQATVSWWLHHWF-------------------RQRKVLLQD-----YATCSESDGIWCGGATTSYIDLALRL------------ +--------------------------------------------------------------------------------------------------GGTWIVPGLGLDHTRLDDAQRAARALAAQVAAGGQVAASCSAVFLLQAG-------GLLHGRCVTTSWWLAPTL-------------------QQWACTVDA-----DRMVCADGPIATAGAAFAQTDLMLHL------------ +-----------------------------------------------------------------------------------------------GPARPWVVVPGIGSASRRLPDVQSAVEWLAKAID--SRIAASCTGTFVAAEA-------GALGGRAVTTTWWLAGLF-------------------AARDCRLDA-----DRMLVKDGPVFTAGASMGHIDLVLAI------------ +--------------------------------------------------------------------------------------------------SSVIVFPGIGLDHHRMPDAEAFARLAQRHHARGGKVAASCSGVLLPAMA-------GLLQGGAATTHWRLSGFF-------------------HKHQIRLDT-----KRMVVESHGIVSAGAAMAQMDLMLYL------------ +------------------------GAEEMEAVITADILRRGGVEVTYAGLNGNPVKCSRKTV----------------------ITPDSALKDVMSKTFDVVILPGGQPGSNTLAGSDVVSQVLKAHHTAGKYVAAICAAPIALKSH--------SIPAALVTSHPCVRK-------------------QLEDGGYKYS------EERVVVADRVVTSRGPGTAFEFGLKLVE---------- +-----------------------DGVQIIDFAGPYEVFGTAGFGVTTVSVDGKPVKTAMTVTPD------------------------TSFAD--APAFDVLLVPGGD--VDAAQKNAAVLDFIRARSAPSRYVLSVCTGAFILGAT-------GLLDGLKATTFRPAIEGL----------------------------------------------------------------------- +-----------------------EGAQAIDFVGPIEVFGQAGFRLTTVSKTGKEITTAMKVTPA------------------------QSFAN--GTLFDAVLIPGGN--INGALINEQVQNWIKAQSREADYVMSVCNGAFILANT-------GLLNGLYATTIEKAFDSF----------------------------------------------------------------------- +-----------------------DGAQAIDFVGPVEVFGQAGFRLTTVSKDGAEITTAMKVTPD------------------------QRLEP--AMKFDAVLIPGGS--INGRLIEPVIQNWIMAQSQSAHYVMSVCNGAFILANT-------GLLDGLYATTIEKAFDSF----------------------------------------------------------------------- +-----------------------NGVEIIDYTGPYEMFGGASYDVFTVAETLAPVTTAMTVVPK------------------------HAFAD--APQADIVVVPGGG--VTEAQHSKPTLTWVKQQSTRVQQLMSVCNGAFILANA-------GLLDGLNATTTYINLEKL----------------------------------------------------------------------- +-----------------------DGVQIIDYTGPYEIFGQAGYDVYTVSKTGQMVSTAFKVQPN------------------------YSFAN--VPQPDILVVPGGQ--VNAARKDKATLAWLNSVYPQTQNLMSVCTGAFILAEA-------HLLDGKTATTFHRSLAKL----------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DVMIFPGGMPGSTELAGFGKLMNIMQEHYAEGGTVAAICAAPSVVLGQL------PNLEGKKMTCYDGFEQ-------------------ALIDKGVEYSK------EGVVVDGNIITGRGAGWAIDFGLAIL----------- +--MKKALIILTEAY--A----------DWEVSYVTAELMSHGFDIDTVSL-GESTV--TSIG---------------------QLKTTYTIDNI-KDSYDALIIIGGNN--WSQIENEQLAQLIKTSLDNNIVVGAICAAVDFFARN-------GLLTGYKHTGNDLN---------------QWTTEENYKA----YTNALDFMNEDSVVDKNLVTANGS-SAVDFA--------------- +----------------------APGSEETEAVTTIDLLVRGGIKVTTVSVDGNLAICSRGV----------------------KLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIVAAICAAPATVLVPH------DIFPIGNMTGFPTLKDK-------I----P----------AEQWQD------KRVVWDVKLLTSQGLGTAIDFGLKIIDL--------- +---------------------------QTEAVTTIDLLVRAGIKVTTASVDGDLKICSRGV----------------------KLLADAPLVEVADGDFDIVVLPGGLKGAECFRDSPLLIETVRQFHLSGRIVAAICAAAGTVLVPH------ELFPIGNMTGFPDLKDT-------I----P----------EGQWQD------KRVVWDVNLLTSQGPGTAIDFALKIIDL--------- +---SSVLLVLSSERRLYSQTPSDAGVPLASLLAIHSILTSSGLAYQIATPAGAPPSCSDSLS-D-LDKSCR-----LPTALLEKLKTPLPVRSVALENFGGVLFPHALGAAVDLFNSSALGALVHSLS-ADKVVCSIGYGGFALAA-KRPSGSSFPFVNYTLTGISPFDECRYP----FFGHLPCMLQELLESLGATFASFECTDTPGMLVDRNLVSGANDASTPLCVQTF------------ +---SSVLLVLSSEKRLHLQKPSDAGMPLASLLAIHSILTSSGLSYQIATPAGAPPSCSDSLS-D-LDASC------LPSALLEKLKTPLPVRSVALEHFGGVLFPHSLGAAVDLFNSSALGALVHSLS-ADKVVCSIGYGGFALAA-KRPSGSSFPFVNYTLTGISPFDECRYP----FFGHLPCMLQELLESLGATFASFECIDTPGMVVDRNLVSGANDASTPLCVQTF------------ +---SSVLVVLSSEKRLYAQTPSEAGISVTSLLSIHSVLTSSGLGYQIATPAGAQPACNDSVA-D-LESDSR-----LPRELLAKLKSPVALRAVKLENVAGLLLPHHLGAAIDLFNSSALGSLLAALSTQDKFVCSIGYGGFALAA-KRPSGSSFPFANYTLTGISPFDECRYP----FFGHLPCMLQELLESQGAAFASFECTDTPGMLVDRNLVSGANEASTTLCVQTF------------ +-----------------------------------------------------------------------------------------------GGCXDVLFVPGGAGTRDANIEVTQIIDYVRDVYPSLQHILSICTGAGILARA-------GVLDGRNATTNKRAWAQT-------------------TALGTNWIA-----KARWVVDGNVYTSSGVSAGI------------------ +-----------------------------------------------------------------------------------------------SKQYDIILVPGGPGARPNV-ISPSVYEFVRKQAPQAKYVLSVCTGSWILADA-------GVLDGKRATSNKAAFRDL-------------------VASSIQWVP-----KARWVVDGKIWTASGVTAGA------------------ +-----------------------------------------------------------------------------------------------APHLDVLLIPGGYGTRGSPPGLDEAIDFIRARFPELKYMITVCTGSRLAARS-------GVLDGLRATTNKRAWLDT-------------------REMAVKWVA-----HARWVVDGKCWTSAGVSAGI------------------ +-----------------------------------------------------------------------------------------------QEYYDLLERPPSKGGRISK-ASSCTRDLIRQHINAGKSVFTTCTGSTVLAST-------GLLDGKNATINHAGYKWA-------------------KEN-----Y-----PAKWVVDGNIWTGACAVAGM------------------ +-----------------------------------------------------------------------------------------------PGDYDLILIPGGDVAPLDP-ANAALNDWIVGRSAAAECGMAVCTGTIQLATT-------GLLDGCRATTNKKDYTAT-------------------IPYGVDWVP-----EARWVKDEKFFTSSGVSAGI------------------ +-----------------------------------------------------------------------------------------------APPLDLLFVPGGLGTRGSNPVIEEVISYIRNTYPQLGYLITVCTGAGLAARA-------GVLDGKRATTNKMAWTET-------------------TGLGVDWVP-----RARWVVDGNVWSSSGVSAGI------------------ +-----------------------------------------------------------------------------------------------APPLDVLLVPGGQGTRAQSPAISESVEFIRQRFPSLQYLITVCTGSGLAARS-------GVLDGRRATTNKLAWEST-------------------TALRVKWVH-----RARWVNDGNIWTSSGISAGI------------------ +-----------------------------------------------------------------------------------------------APSLDLLIVPGGQGTRD--PKISKAVSFVTRVYPSLQQLIAVCTGVGIAAQA-------GVLDGKRATTNKLSWDST-------------------VALRVDWVY-----QSRWICDGNIWTSSGISAGI------------------ +-----------------------------------------------------------------------------------RFVATHTFTDA-P-PLDILFVPGGGGNRAHENNDTVIEDFIASRFDELQYVLSVCTGAATLAKS-------GVLAGRRATTNKATWNWTTQF-------G---------DGKVEWVP-----TARWTEDGKVWTSSGVAA-------------------- +-----------------------------------------------------------------------------------SIEATHTYIDA-P-AIDVLFVPGGLGTIPDQTNDTWVEDFINSRIDRLDYIASVCTGAQFLAKS-------GILKGKKATTNKASWERIVVH-------G---------E-DIEWVP-----TARWVEDGKIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------SFNPTHTFDNP-PDDIEILLVPGGLGMRR----SEPVVDFVRKT-PKVKYLLTTCTGAGVAARA-------GVLDGKRATTNKAAWNEIV-M-------G---------P-NVKWVS-----PARWTVDGNIWTSSGVTS-------------------- +-----------------------------------------------------------------------------------TVMATHTFRNA-P-ALDVLLIPGGIGNVAAQANDTSVEDFVRLRFDQVDYLLSVCTGAMSLAKA-------GVLDGRRATTNKSAWASVVGS-------G---------T-NVTWVP-----SARWVQDGKIWTSSGVSS-------------------- +-----------------------------------------------------------------------------------SVVATHTPENA-P-PLDLLMVPGAPV-ANNSGNDTWREDFIKARFNSTDYVASVCTGAMSLAKA-------GVLENKRATTNKLDWSEVVKY-------G---------K-NVIWVP-----SARWTHDGKIWTSSGVAA-------------------- +-----------------------------------------------------------------------------------KLVATHSFSDA-P-ALDVLLVPGGFGPVTEQNNDTSIETFLRRRFDQLEYLLSVCTGSAILASS-------GLLNGHRATSNKALWSWVTTH-------G---------E-NVTWVP-----SARWTEDGKIWTSSGVAA-------------------- +-----------------------------------------------------------------------------------TINPTHTFATA-PDDIEVLIVPGGPGVRA----VSPMTDFIRDRYPKLRYLLTVCTGAGLAAKS-------GVLDGRKATTNKSAWATITSY-------G---------P-NTTWVS-----PARWVVDGNIWSSSGATA-------------------- +-----------------------------------------------------------------------------------EVLPSYSFVDA-PKDIDVLLVPGGQGVRA---SSQAAVDFVKARYPTLKYLLTVCTGAVLAARA-------GVLDGKRATSNKRSFTWVVSQ-------S---------D-KVTWIR-----EARWVIDGNIYTSSGVSA-------------------- +-----------------------------------------------------------------------------------SINPTHTFASP-P-PLDVLLVPGGIGAMD---KIQSAIDFVAKV-PSLQYLITVCNGAGIAARG-------GVLDGKKATTNKMRWWPET-Q-------R---------E-QVKWVG-----HARWVVDGNIWSSSGVSA-------------------- +-----------------------------------------------------------------------------------VPVSAVGPNEI-D-HRGILLIPGGDGTRP--SKDRQWLDRLRDLSCEASHVLTVCTGSALLAAT-------GLLNGRRATSNDLAFDWVTSV-------S---------D-RVTWIR-----DARWTVDGNFRTSSGISA-------------------- +-----------------------------------------------------------------------------------SIVPTDTLATA-ADDLHALFVPDGVGTLA--PDLQPRIDYITTTYPSLTHLISTCTGA-------------GVLDGRNATTNKAMWNETVSH-------G---------P-RTNWIG-----HARWVRDGNVYLRSGVS--------------------- +-----------------------------------------------------------------------------------AKIWTRKLSEI-A-KFDVLLVPGGFAARE--AHDGEFIAALGELSRRHEYVIAVCTGSVLLAKT-------GLLDGVEATSNKLSWQWATSE-------A---------P-SVRWVR-----AARWCVSGKFYTSSGVSA-------------------- +-----------------------------------------------------------------------------------EVIAELEYGEL-N-DPDIILVPGGMGTRT--ARDKSFLSWLTDIGTRSEIVASVCTESALLAAA-------SLLESHRATSNKLAFEWASSF-------G---------N-DVSWEY-----QARWIHDGCRWTSSGVAA-------------------- +-----------------------------------------------------------------------------------RVECGRSFRELSE-PIDILLVPGGPGTRT--VDDAPFLAWLTEAGARARLLASVCTGSALLAAA-------GLLEGYRATSNKAAFEWARTF-------G---------Q-TVAWQR-----EARWVEDRDRWTSSGVAA-------------------- +-----------------------------------------------------------------------------------QVIATRCATDL-E-TVDILLVPGGAGSRT--VDDAEFLDWLNNLGSRARLVASVCTGSALLAAA-------GLLEGKRATSNKLAFDWATSF-------G---------N-EVTWVK-----AARWVEDGDRWSSSGVAA-------------------- +-----------------------------------------------------------------------------------QVIATRCAADL-E-TVDILLVPGGAGSRT--VEDAEFLDWLNNLGSRARLVASVCTGSALLAAA-------GLLEGKRATSNKLAFDWATSF-------G---------N-EVTWVK-----AARWVEDGDRWSSSGVAA-------------------- +-----------------------------------------------------------------------------------SVVPTHTYETA-PDDIEVLLVPGGFGARN---NVKRVREFVKER-PKLKYLLTVCTGSAIVAQT-------GILDSREATSNKRSFDWVL-Q-------G---------P-DVKWAR-----NARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------HILPTHDLHSS-PEDIEVLLVPGGRGTRD---STQPQVDFIKSR-PKLQYLLTVCTGAALAARA-------GVLDGKKATSNKAAFEWVK-Q-------G---------E-KVDWVP-----GARWVKDGTTWTSSGISA-------------------- +-----------------------------------------------------------------------------------PLYASVGYQDAPQ-SFDIFLIPGGRGRIN--VKDQGILDYIRTAAEQSTHVLTVCTGSGILART-------GFLDGKNATTNKLTYDEIVGA-------S---------P-SVNWIR-----KARWVVDGKIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------SLSPTHTFSSP-PSPIDVLFVPGGFGCRA-----TEAEEFLRAR-ETCQYLLTVCTGSALSART-------GILDGKKATSNKKSFEWVK-Q-------G---------P-KVEWIR-----KARWVADGRCWTSSGVAA-------------------- +-----------------------------------------------------------------------------------VPVQTLPVSGD-D-KPDVLLVPGGGGTRP--SKDASFIAMLDSLASRSEHCLTVCTGSALLAAT-------GQLDGRRATSNKRALNWVKSV-------R---------T-QVNWQN-----QARWESDGKYVTSSGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFDNA-PDDIEVLLVPGGFGTRQ---LVESAVDFVKSA-PKLRYLLTVCTGSALVAMT-------GLLDGKRATSNKRAFSWAM-Q-------G---------P-NVQWVR-----EAR--------------A-------------------- +-----------------------------------------------------------------------------------RIVPTMRFKSF---SGDTLLVPGGRGTRS--VQDPEFLRQLAALASSADIITSVCTGSALLAAA-------GLLENHSATTNKSAFDWARTH-------G---------Q-KIEWKK-----QARWVRDGNLWTSSGVAA-------------------- +-----------------------------------------------------------------------------------AIVPTHNFTNP-PPKLDVLFVPGGIGTRA-APELDAHIAFIRKT-PSLQYIVSVCTGSWLLARA-------GVLDGKNATSNKRAWAGTA-L-------G---------N-GTNWIT-----HARWVQDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SVLPTHSFANA-PPEIEVLLVPGALGTRD---ATQPVVDLVRKI-PKLRFLLTVCTGAALAART-------GVLSSKRATSNKLALEWVV-P-------G---------N-DVRWVR-----RARWVQDGNVWTASGVSA-------------------- +--------------------------------------------------------------------------------------------------FSPLCCPRTPTTTR---STSTSSSFIAKAYPRLDYLVAICTGVGLAAKA-------GVLDGKRATTNKASWERIVPS-------G---------P-RVKWER-----RARWTVDGKLWTSSGVTA-------------------- +-----------------------------------------------------------------------------------EVTSDVSYSDLRG-GTDIVLVPGGPGSRT--ISDAGFLSDVATICRRASVVTSVCTGSAVLAAA-------GVLDGRRATSNKKSWSWATSQ-------G---------R-GVTWVP-----QARWVVDDSIWTSSGVAA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFDDA-PDDIEVLLVPGGIGARD---HSQKVVDFIRGR-PKLKYLLTVCTGSALAARA-------GVLDGREATSNKKSFKWVV-Q-------R---------S-EVKWVQ-----EARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SVVPTHSLDNA-PEDLEVLLVPGGGGTRQ---STEPLVAFLRAT-PKLRYLLTVCTGSSLAARA-------GLLEGKKATTNKLAYKWVV-L-------D---------D-KVDWVA-----KARWVTDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SIVPTHTYEDA-PSDIDVLLVPGGLGTRD---CIAVVVAYIQKT-SRLDYLLTVCTGSALVAKS-------GVLDGRRATSNKRAWKWAI-Q-------G---------P-KVDWVL-----KARWVTDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SIVPTHTYEDA-PSDIDVLLVPGGLGTRD---RIAAVVAYIQKT-PRLDYLLTVCTGSALVAKS-------GVLDGRRATSNKRAWKWAI-Q-------G---------P-KVDWVL-----KARWVTDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SVMPTHTFADD-P-ELDVLLIPGGWGGFE------ATRDYIRQV-PKLGSLITVCNGSALVAQT-------GILDGKTATTNKAYWKECT-S-------G---------P-KTSWVA-----KARWVRDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------SIVPTCTLEDA-RTDYDLLIVPGGFGTTK----VDPYVDYIKRA-PTTGSVLSVCTGTRLFARA-------GILDGRRATTNKNAFNDVT-L-------G---------P-KTHWVA-----KARWVKDGNVWTAAGITA-------------------- +-----------------------------------------------------------------------------------SIVPTHTFGTA-P-PLDVLLIPGGLGTMG---ILQEIIIFIQRV-PRLKHLITVCTGSGLAAQA-------GVLDGKRATSNKKVFKEII-L-------R---------P-QVHWVY-----HARWVTDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------TIVPTHTFSSA-P-PLDVLLIPGGYGTRG---GLEEAIDFIRSR-PELKYMITVCTGSRLAARA-------GVLDGLRATTNKRAWLDTR-M-------A---------P-GVKWVA-----HARWVVDGKCWTSAGVSA-------------------- +-----------------------------------------------------------------------------------SIVPTHTFATA-PRDIQVLIVPGGRGTRD---GTHPVVDYIRET-PRLRYILTVCTGSVLLARA-------GLLDGKRATSNKSRFDTVV-S-------A---------P-QVDWIR-----RARWVTDGNFWTSSGISA-------------------- +-----------------------------------------------------------------------------------RLCVDAALSDG-T-DFDVLLVPGGDSALT--AIDEETLGWIRNVSARAEVVLAVCTGTIVLGMS-------GVLDGKRATTNKLDFNATIGL-------A---------P-AVDWVK-----SARWVEDGKYFTSSGVSA-------------------- +-----------------------------------------------------------------------------------SVLPTHTFDDA-PRDLEVLIVPGGRGSRD---STARLVDYLRHT-PRLRYLLTVCTGSAFAARA-------GVLDGKRATTNKICFGWVT-F-------G---------D-KTEWVP-----KARWIADGNVWTSSGISA-------------------- +-----------------------------------------------------------------------------------SVVPSHTYKNA-PEDIEVLLVPGGRGTRN---RTQHVADFIKER-PKLRYLLTICTGASIAARS-------GVLDGKNATTNKMAFDWVI-Q-------G---------P-NVKWAR-----RARWVCEGNVWTSSGLTA-------------------- +-----------------------------------------------------------------------------------EVLPTGTFADFLAKKIDVLVVPGGAGTRF---LIDPVIEIVRAI-PSVKYIMSVCNGAGVLARA-------GVLDGRRATTNKMLWKPTT-L-------R---------G-DVRWVR-----EARWVADGKVWTSSGVSA-------------------- +-----------------------------------------------------------------------------------EVLPTGTFADFLVKKIDVLIVPGGAGTRF---AINPVIEFVRGI-PSVKYIMSVCNGAGVLARA-------GVLDGRRATTNKMLWGQTT-L-------R---------G-EVRWVR-----EARWVADGNAWTSSGVSA-------------------- +-----------------------------------------------------------------------------------RMVADFSLDNA-P-DVDVIVVPGGTASEE---LDGRVTDFLKTRYPTLKYLIGICTGGAIIAAS-------GLLDNKRAAGSKSFWSWVSSQ-------G---------T-NVSWIP-----KARFMNDGNIWTSSGLTA-------------------- +-----------------------------------------------------------------------------------RMVADYSLDNA-P-DLDVIAIPGGTT-EE---SSGRVAKFLKARYPTLKHLIGICTGGAIIAAS-------GLLDNKRAAGTKSVWSWVSTL-------G---------T-NVTWIP-----KARFMNDGNIWTSSGLTA-------------------- +-----------------------------------------------------------------------------------KVVPTMTYSEALK-QFDIIIVPAGS-MSG--EIEQEAVMFLAKQSPGAKYVLTVCGGSAILAAT-------GFLNGKRATTNKAGFKMIQAA-------F---------D-KVNWVP-----KARWVVDGNIWTASGITA-------------------- +-----------------------------------------------------------------------------------RVSPTSTYGAALK-QYDIIVIPAGSSWIG--AQEQEAVDFITKQGAKAKYVLSVCLGSGILAAS-------GLLDGKRATSNKMFFKEVAGV-------F---------P-KVNWVP-----KARWVVDGKFWTGSGVTA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFDSP-PEKIEVLLIPGGGGTRS---SAEPVVEFIKKI-SSIRYLLTVCTGSGLAARA-------GVLDGKRATSNKRAWKEVT-L-------R---------T-EPIWVQ-----RARWVAEGNIWSSSGISA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFATA-P-SLDLLFVPGGLGTRV---AIEEAIVYIRNV-PQLSYLITVCTGAGLAARA-------GVLDGRRATTNKMAWAEIT-L-------G---------V-NVDWVP-----RARWVVDGNVWSSSGVSA-------------------- +-----------------------------------------------------------------------------------LIQPTHTFSSP-PTDLDVLLVPGGLGTRD---ATAPAVSFIRDV-PRLQYLVTVCTGATLAARA-------GVLDGRRATTNKMAFREIS-A-------Y---------P-AVQWVA-----RARWVVDGNVWSSSGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHTYANP-PENIDVLIIPGGTGNRD---VLEPVSKLTRDL-PGLQYLFTICTGSKIPAHA-------GILEGRKATSNKIAFGEVA-A-------Y---------P-KVNWVE-----RARWVVDGNIWTTSGISA-------------------- +-----------------------------------------------------------------------------------TLVPTHTFATA-PLDLDVLIVPGGVANFNTLELMRPMLDFIKERYPRLKHLITICTGSGIVSQT-------GLLDGKKATMFKGAWPIISKW-------R---------E-EVNWIS-----KARWTRDGNIWTSSGVTS-------------------- +-----------------------------------------------------------------------------------SIVPTHTFENV-P-EIDVLIVPGGMGNRP---TMDSVINYIRQV-PRLQHLITVCTGSWLVAQA-------GILDGRKATTNKASFKRIA-L-------C---------P-SVEWVG-----RARWVVDGNIWTSSGVTA-------------------- +-----------------------------------------------------------------------------------PIVASYAFASA-P-ALDVLLVPGGKGCRS--FHDAAYQDFIKYHSSRVQYVLSVCTGSGFLAAC-------GLLDGKRATTNKVAFREIQML-------G---------DGRVQWIK-----HARWVVDGNIWTSSGVTA-------------------- +-----------------------------------------------------------------------------------PMVASHSFESA-P-RIDILLLPGGLGTDV--AKDPAYLAFVRARAESATFILSVCTGSSFLAAS-------GLLDGKRATTNKLAFQHIQSF-------G---------SSAIQWVK-----QARWVVDGNIWTSSGVTA-------------------- +-----------------------------------------------------------------------------------SIVPNHTFETG-P-PLDVSIVPGGIGNRI---NVETAIDYVRKV-PTLRYLITVCTGSRLVAEA-------GILDGRRATTNKRAWATTI-Y-------R---------P-EVEWVP-----HARWVVDGNIWSSSGVSA-------------------- +-----------------------------------------------------------------------------------SILPTHTFETA-P-AVDVLIVPGGIGNRV---NISKAIDYIARV-STLKFLITVCTGSAIAAQA-------GVLDGKRATTNKRAWSRTI-L-------R---------P-QVEWVA-----HARWVVDGKIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------TLQPTHDFKTA-P-ELDVLIVPGGMGSFDGPAVVDPIVEFVRDRYPKLKYLLTVCTGSGIVSQT-------GLLDGKRATLFKGAWEVIPKW-------R---------P-QVQWQP-----RARWTEEGNIWTSSGVSS-------------------- +-----------------------------------------------------------------------------------SIVPTHTFDSP-PSDIEVLLLPGGMGTRS-DI-MKGPIKFVKDI-PSLKFLITVCTGSTIASRA-------GVLDNKRATSNKRSWEWVI-Q-------G---------P-RVEWVP-----HARWVQDGNIYTSSGVSA-------------------- +-----------------------------------------------------------------------------------PSVAEHRFADA-P-SYDLLLIPGGFGTRA--VSKSSFLDQLGAASQRAATTATVCTGSALLART-------GLLDHRPATSNKLAWDWVVQQ-------G---------P-QVQWIR-----QARWVDDGDIITSSGVSA-------------------- +-----------------------------------------------------------------------------------CIVPTHTFAQA-REGLDVLVLPGGLGTRT---NVREVVEFVKSLGPEG-----------------------------------VRW-MLT-K-------H---------P-AVQWVP-----KARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------RVQPDAQFDDE-L-PCDVLIVPGGVIDQP--VNDPQTLAWVRRMASSTGLLTSVCSGALILAKA-------GLLQGHSVTTHWADIQELREG-------Y---------P-DLDVQE-----NVPYVDAGSLVTSAGISA-------------------- +-----------------------------------------------------------------------------------SLVPTHTFDSA-PDDLDVLLIPGGMGSRG-DEHMGPLVEYLKKLDGRLKWVLTVCTGSEILART-------GALDGRRATSNKRAFNNVK-L-------H---------P-NVDWVA-----KARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SLVPTHTFDSA-PDDLDVLLIPGGMGSRG-EERMGPLIDYLKKLDGKLKWVLTVCTGSEILART-------GALDGRRATSNKRAFNNVK-L-------H---------P-NVNWVA-----KARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------RISPTQTYQGALT-QYDILWVPAGPMSDPEDLTPKSEVDFLAAQAPGAKYVMSVCAGSAILAKA-------GVLDGKRATTNKWLYRVIEKE-------S---------P-KVNWVA-----DARWVIDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------TVLTGYSYANP-P-PLDVLLVPGGVGTRN--AGVAPVIAFVKEVYPSLQYIISVCTGASILARA-------GLLDGKRATTNKRAWAFVTQF-------G---------Q-RVRWNP-----KARYIRDRNVWTTSGVSA-------------------- +-----------------------------------------------------------------------------------VILTDATFANP-P-PLDVVIIGGGGGTRN--TTMAPVIEFAKNIYPSLQYIISVCTGATVLARA-------GLLDGKRATTNKKAWAWATTF-------G---------N-RVRWQP-----HSRYVRDQNVWTTSGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHTLANA-PSDIEVLLIPG-PGPRA---DLRDEIAFIRDT-PRLKYLIAVCTGAWLAADS-------GVLDGHNATTNKAAWAER--V-------N---------N-TVNWIA-----HARWVVDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------SLQPTHTLSSP-PPDLEVLIVPGGIGTRA--G---AEVDFIRTIFPSLRYLISICTGNVLVARA-------GLLDGKKATGNKKSWSWLTQQ-------G---------N-KTHWVA-----KARWVVSSKIWSTSGVSA-------------------- +-----------------------------------------------------------------------------------KVLPTHTFATA-PAALDVVLIPGGQGTRT---TIQPAVDFIRRRFPDVRLVLTICTGVVVVARA-------GLLNGERATTNKSKFGWVVAG-------S---------P-DAVWVE-----RARWVEGDKIWSASGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHSYDDL-PTDIDVLIVPGGLGTSH---NIEPTVKLARKL-PEVKYLFSICTGSKVLAEA-------GLLDGKKATTNKRRYEETT-P-------Y---------P-QVQWQR-----SARWVIDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------TIIPTHTFDNP-PEDLDVLLIPGGVGTWS-TAEFEQTVGFVANT-PHLQYLITVCTGASIAARA-------GVLDGRNATTNKASFAWVA-W-------G---------P-KVNWIT-----HARWVVDGNIYSTSGVSA-------------------- +-----------------------------------------------------------------------------------TIVLTHTFDAP-PKDVDVLIVPGGFGAGPGPAGVERVVQFLRDQYPTLKHLLTVCNGAGLAARA-------GILDGQKATTNKQLWPAITAL-------G---------P-KTHWVA-----RARWVVADKLWTSSGVSA-------------------- +-----------------------------------------------------------------------------------GVIPTLSLAEALEDQFDTLFIPGGFGMMP----DPILLQRIGQLVDRAPNVFSVCTGSILLAAT-------GRLDGRKATTNKRLYDELTPK-------H---------P-GVQWQK-----RARWVQDGKFLTSSGVTA-------------------- +-----------------------------------------------------------------------------------SITPTHTFETA-PD-LDVLVIPGGPGWRN---TLNATMEYVRKTTPKVQQVLTICTGSALAARS-------GILNGKRATSNKSSWLSTVQN-------N---------P-NTTWVP-----HARWVEDNPIWSSSGVTA-------------------- +-----------------------------------------------------------------------------------AIVPTHTFDTA-PQDIEVLMIPGGGGTRD---ATQPLVDYAARV-PKLRYFLTVCTGAALAART-------GILDGKKATTNKLAFDWVM-K-------G---------P-KVHWVR-----HARWVSDGNIWTSSGISA-------------------- +-----------------------------------------------------------------------------------VYLPTHTFDTA-P-PLDVLILGGGLGSLP---QVQPEMDFLKTVFPSLRYLFTVCTGSGIAARA-------GLLDRLRATSNKAVWEQVV-C-------G---------P-KTHWVA-----RARWVAAG-VWTTSGVSA-------------------- +-----------------------------------------------------------------------------------ANYINYNFENC-P-DFDILFIPGGVGTRD--LENSVFLDFIKQRVPKVKYVLTVCTGSGLLAKT-------GLLDGKKATTNKLVWNWMTSF-------G---------P-NVEWVR-----KARWVVDGKFYTSSGVSA-------------------- +-----------------------------------------------------------------------------------TILPTHTFNTA-P-PLDVLIVPGGQGTRY---GIRASIDFIKER-PELQYLITVCTGAGVAARA-------GVLDGKRATTNKLSWEQTI-L-------R---------P-EVNWVH-----KARWVEDGNVWTSSGISA-------------------- +-----------------------------------------------------------------------------------VILPTHTYETA-PEDIEVLIIPGGLWTRS---NIGPAISYIKTT-PRLRYLISVCTGASVVARA-------GVLDGRRATTNKASWASTI-H-------G---------P-RTEWVA-----KARWVVDGNVWSSSGVSA-------------------- +-----------------------------------------------------------------------------------RIAPTHTFANA-PSDLEVLIIPGGLGTRS----ATELVQFVKDTYPRLRHLITVCTGATFAAKA-------GLLDGRRATTNKNLWAETTPW-------A---------G-TVRWVP-----RARWVEDGNVWTSSGISA-------------------- +-----------------------------------------------------------------------------------SINPTHTFADP-PPDIDVLFVPGGGGERF----NSAAVDFVRRTYPKVRYLITVCTGAGVAAQA-------GVLDGKRATTNKWAWKDVVSN-------G---------N-NVQWTS-----PARWVVDGNIWTASGVVS-------------------- +-----------------------------------------------------------------------------------EVLPTHTYDTA-PD-LDVLILPGGPSVRA----LNSTYDFIAQRYPTLKYLITICTGAGLAAKA-------GVLDGKRATTNKSAWATILAM-------G---------L-NVKWVS-----PARWVVDGNV------TA-------------------- +-----------------------------------------------------------------------------------SVVPTHDFNNA-P-PLDVLIIPGGYGVRA-D--LDPLFDFVRRT-PSLKYLLTVCSGSWIAAQA-------GILDGKRATSNKNAWASTK-V-------G---------P-NVKWVS-----HARWVVDGNIWTASGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHHFNNA-P-PLDVLIIPGGYGVQA-D--LDPLFDFVRRT-PSLKYLLTVCTGSWIAAQA-------GILDGKRATSNKNGWAYTK-V-------G---------P-NVKWVS-----HARWVVDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------SIIPTHTFDTA-P-DLDVLLIPGGVGTRS-DPFFDDHLAFIRSR-PKLRYLITVCTGAHLAAKA-------GILDGRNATTNKRAWDLAP-Y-------G---------P-KVRWIA-----HARWVADGKVWTSSGVNA-------------------- +-----------------------------------------------------------------------------------SILPTHTFDTA-P-PLDVLLIPGGIGTRS-DPFFDEHLAFIREQ-PKVRYLITVCTGAFIAARS-------GVLDDRNATTNKHAWADAP-Y-------G---------P-KVKWIA-----HARWVVDGKVWSSAGVSA-------------------- +-----------------------------------------------------------------------------------VILPTHTFAAA-PE-LDVLLVPGGAGVRA----VKNITDFIADRYESLEYLITVCTGAGLAAKA-------GVLDGRRATTNKSAWSTVTAW-------G---------P-NVNWIR-----QARWVVDGNIWTGAGVTA-------------------- +-----------------------------------------------------------------------------------SIMPTHTFKNA-P-PIDVLLIPGGYGTDS----IGPAVEFIKKIYPSLQYVLTVCTGSQLLAQA-------GILDGRHATTNKQAYNRVTKH-------G---------P-NVKWVP-----EARWVADGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------SIMPTHTFKNA-P-PIDVLLIPGGYGTDS----IGPAIEFIKKIYPNLQYVLTVCTGSQLLAQA-------GILDGRHATTNKQAYKRVTKH-------G---------P-KVKWVP-----EARWVADGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------YLRPTHTIYDN-I-PLDVLLVPGGGPESAVQFNNTRLINYVKRTYPSLQHILSTCTGAQFLAKA-------GILDGKKATTSKFSWKDIIKT-------G---------P-R---VP-----CARWVRDGNIWTSSGVTS-------------------- +-----------------------------------------------------------------------------------WVKPTYTIDQD-P-ELDVLLIPG-GQGSRVAYNNTRIINYIKRTYPKLKYITSVCSGAQLLAKA-------GILNGKRATTNKFSWAELTAS-------G---------P-GVNWVP-----CARWVVDGNIWTSSGIAA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFANP-PKDLEVLFVPGGLGTRA-EPALLDVIAYIKET-PSLRYIVSVCTGATLLARA-------GILDGKRATTNKKAWGEVT-L-------G---------P-NVKWVP-----VARWVEDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------EIVPTHTFTNP-PE-VEVLIIPGGYGTRN---KMAPVESYIRSVFFDLKYAITICTGSAVLAGM-------GLLDHRRATTNKCTWSLVTPL-------G---------P-KVNWVR-----KARWVVDDPVWSSSGVSA-------------------- +-----------------------------------------------------------------------------------KYLPTHTFETA-P-QLDVLLIPGGVGAAPGLSHMQEYLEFIRSTYKPLKYILSICNGAGLLAAA-------GILDGKKATTNKELWKFVTKL-------G---------P-KTHWVS-----HARWVCDGNVWTTSGVSA-------------------- +-----------------------------------------------------------------------------------QYLPSHTFAEK-P-EIDVLIVPGGMGMVG---DLPELQDYIRKAYKKLHSIISVCTGSVLMARS-------GILDGQRATGNKDAWDVVTSS-------G---------P-KTHWIA-----QARWTNSENIWSTSGVSA-------------------- +-----------------------------------------------------------------------------------SVNPTHTLADP-PKDLDVLFVPGGAGTRD--AEVTQIIDYVRDVYPSLQHILSICTGAGILARA-------GVLDGRNATTNKRAWAQTTAL-------G---------P-ATNWIA-----KARWVVDGNVYTSSGVSA-------------------- +-----------------------------------------------------------------------------------LYVPTCTVHDA-P-SIDLLIVPGGPGSVK---VMKPFVEYIRKLHKPPKYFFSICSGSLLFAQA-------GILDEQSATTNKAFWTNITAQ-------G---------P-RTKWIA-----KARWVVSGNIWTTSGVTA-------------------- +-----------------------------------------------------------------------------------SVVPTHTFANP-PEDLDVLFVPGGAGTRA-DLRLTELIAYIRDV-PSLQYIISVCTGAQLLAQA-------GVLDGRNATTNKAAWASMT-Y-------G---------P-RTYWRA-----QARWVKDHNVYTTSGVSA-------------------- +-----------------------------------------------------------------------------------SILPTATLTSS-P-PLDVLLIPGGWGTRA--P---EHIEYIRSVYPSLKYLLTVCTGGKLAARA-------GVLDGKRATTNKNDWESVVRD-------A---------P-RVEWVR-----EARWVVDKEVWSSAGVSA-------------------- +-----------------------------------------------------------------------------------SILPTATLSSS-P-PLDVLIIPGGWGTRA--P---EYTEYIRTVYPTLKYLLTVCTGGKLAARA-------GVLDGKRATTNKNDWEGVVRD-------A---------P-GVQWVK-----EARWVVDREVWSSAGVSA-------------------- +-----------------------------------------------------------------------------------SVVPTHTLADA-P-PLDVLLVPGGLGTRA-D--LNATIGFVADV-PSLQYLITICTGAGLAARA-------GVLDGRNATTNKKSWAATT-L-------R---------K-QVNWIP-----EARWVVDEKVWSSSGVSA-------------------- +------------------------QVQLLDLAGPVQVFDTAAYTLLFCATS-EEIRSAQHLS----------------------LARLQRLPD--IDGRSLVIVPGTGASPSRNLLNEETKPWLQENYHAGAQVASICSGTAALGEA-------ELLHRRRCTTHWKFLSEL-------------------QSCTAQVVD-----GVLYVHDHGIITSAGVASGIDMALWLLE---------- +------------------------RVHILDLAGPLQVFQEARLTIEFCSVQ-HEISSSIELI----------------------INNLNHFSKIRFSPGDYLFVAGAEVAYSAR-QQSSLMQWIRDAHAAGAVVCSVCTGAFLLAEA-------GILNGLKCTTHWKRTAEL-------------------QQRAVKVVD-----DILFTEDNRILTSAGVTAGVDLALGIVS---------- +------------------------QVTLLDLSGVLQVFQEAIYKLQFISSQ-SSVICSSGLE----------------------LASLTHFSKTKPQKEDIIFISGFSTHQL--HEDPSFFEWLQEINANQITICSICSGAFLLAKA-------GLLDHKQSTTHWKLVDKL-------------------QKDLTQTQN-----NTLFSQSGNIYTSAGITTGIDLALHIIE---------- +------------------------QVHILDLAGPLQVFYEAKFDLQQVALA-PEVSMAQGLT----------------------LSHLAPYTTLSLQKGDYIIIAGIHTSGSYQQASPAFFAWLNAQHVQGVKICSVCTGAFVLAQA-------GLLDGKKCTTHWKASQEL-------------------HDKAAKVQS-----DCLYIKDQQVYTSAGVASGIDLALSILE---------- +------------------------------------------------------------------------------------------------------MIPAIEGVR-GFSPDARLVAWLAAQHRAGARVLALTTGVCFVAAA-------GLAEGLLMATHWAYVRQL-------------------KKRGGQFVA-----HQSCLQASAIWSTGSLNGAYDALLEMLA---------- +------------------------------------------------------------------------------------------MPA-----TRIVCIPDFFVNP----QYDAEAAWLKRAHDDGAMLASACSGAVLLGEA-------GLLDNREATIHWGYVETL-------------------TNNGVKVKP-----GQSLVLSGRIVMAGGGSSWQDLALYLIA---------- +------------------------------------------------------------------------------------MIAHYDFSTM----PDTLIIPGGQ----Q---NSNTIDWLTQAAG-TRRLASTCTGAFILAKA-------GLLDNREATTHWQYAHTL-------------------RKNSVKVND-----DAIFIKD-NIYSSAGVTSGIDLALSLVE---------- +------------------------------------------RTASNLE----------IAS----------------------HCAINEITE-----TDLVILPSIQLDT----QDPEITQWLKEMHENGALLCSICSGVFLLAET-------GLLDGHEATLHWAHEEHF-------------------RCVDININM-----ERLLVTSGRFVMGGGSSSWQDLLIYLIS---------- +------------------------EVHLLDLAGPCQAFHEAMLNLHFIGDQ-SSFSSYQGLT----------------------IGGVQPLPAT-LPDHAIVIVCASKYHK-QNPASQTCIEWLRQMPKDNTRILGICTGAFLLGLA-------GWLDNRACTTHHKLTQAL-------------------ADQTAKVIP-----ERIFVRDEQIYTTAGVTAGIDLALQLIE---------- +------------------------GMHLLDIAGPCQALHEANFKIYFVGFS-RTVHSHQGLD----------------------LTNILEPPIE-LPERSVIFVCASKYEP-SDQESARSIEWLRQAIREDTLVVGICTGAFMLAKA-------GLVDGKEVTTHHSLTTEL-------------------AQQETHVLT-----DRIFVRSDNIYTSAGVTAGIDTTLYLIS---------- +------------------------RVHLLDAAGPIQAFASANYEISTVADT-ATVTSHQGIA----------------------LGASTTWPE--LSTRDLVMVVGGKLAA-VAPLADHLVLRVAEHHRASGSVASVCAGALTLAQA-------GVLDGLCATTHHELLDRL-------------------A-RGVEVAH-----GVLYTCTPRVHTSAGIASGIDLSLHLIA---------- +------------------------HVNLLDLSGPVQAFSAA-YDLAFVSSD-PLVSSAQGLD----------------------LSGLGALAP--VHDGDLVLIPGADLTM--LEIDPGVIRWIREAADAGAQIASVCTGAFLLGEA-------GLLDGHRCTAHWSVIDHM-------------------RERRARVVD-----DVLFVMDGLILTSAGIASGIDLALAIIE---------- +------------------------GTHILDLGGPLQIMASLEVNVRCIAAR-QQVTSFQGVT----------------------LSGLHQLPER-LAPQDLLFVVGNKLSA-ETAILTATALWLAKVIRQDIKLCSICTGAFLLGEA-------GLLDGRQCTTHHRYVDLL-------------------RTRAAKVLE-----NRLFVEDDGVFTSAGVSSGTDLALHIVS---------- +------------------------TVHLLDFAGPAQVFGDAAFSLHFVADAE-RPVSAQGLA----------------------LLPEAQWPE--LNTDDVILVPGGRALS-AAHLGVASTQRLIEHHQSGGRVASVCSGALSLGLA-------GLLDGRRCTTHHQLQTEL-------------------AKSRAKVIS-----DVLYTEDDGVLSSAGIASGIDLSLHLVA---------- +------------------------RLHLLDLAGPAQVFSTADYGITYVSER--EDVTAQGIT----------------------LRAGTEWPE--LTPDDLVVVPGWRTKG-RVDVPRALLDRLVEHHDAGGTVASICAGADALGRA-------GLLDGRRCTTHHDVQDEL-------------------ARRKAHVVR-----DVLYVTDGRVITSAGIASGIDLALHLVA---------- +------------------------DSVLLDVAGPAEVFQYAQFNLKFIGPV-KQVRNSIGLD----------------------V-RVDPLPSH-IEPNSWLLCTGTVGKN-TSESITRIGHWFDRLAGQFSKFISICSGAVVFASL-------GIFSHRLCTTHHAHLDEL-------------------RETTSKVLD-----NRLFVVDGNVYSSAGISAGIDLALHLVQ---------- +------------------------QMHILDLGGPMQIFASLTIKIQCVGPE-SHIKSYQGIF----------------------LSAIAPLPKR-LTAGDVVVVVGSKIQA-ATPAQQQVTQWLRDIGGKGIVIAS-STGAVLLAQA-------GLLDGRLCTTHHNHLKTL-------------------QQLQARVIS-----KRILVQDGPIYTSAGVSAGIDLALHLIT---------- +------------------------DTQRASLAPLRDLARLSELRLDLLRLGEA-PLESRPIA----------------------FRP-G------GE-YDLVYVAAGEDPA---WGDARLSEWLRWHHDRGAWVVGLGSGVLALAAA-------GLLDGGPASIPPRHARLA-------------------RQRDIRLAH-----VGAIAEHDRVLTAAEPSSVFALVVAMTR---------- +------------------------GVRLGSLGTVSDAMALSDLRVRVLTPTGD-GVAAAGIR----------------------LPA-DGRVGG-DA-AKAVFLPAFDDLA-RPPGWAAVLPWLRQQHAGGALLAAAGASVLALAEA-------GLLDGHETVACGRIAQDI-------------------ETRAVSLLP-----GLPMLATGTLITAATLDGEQELARELVR---------- +---------------------------MLDLASFVEALRSARLTTCAY--GQD-SLAEEWIR----------------------VQAAHDITSA-PL-IDTLILPNSSVSD----QDLECSVFLARRGKSIRRIVALGNGVLLAAAA-------GMTRGQTVAADSAVEERL-------------------ATLQTIVDA-----NYDLHKSGKIWSARGPAVGLSLALALIE---------- +------------------------GTLIMDVAGPAEVFRLANFALQFISPE-HTITSSVGLS----------------------FHDIAPLPDLRKSGPVWLVLSGRSGPT-HDPVWLKARAWLTRYVELGCALLTICAGALLLADA-------GLASGRTLTTHHDFLDEL-------------------ARLQAQVMR-----NRLYVDDGNLLSSAGITAGIDLALHCVS---------- +------------------------NMMALDIVGAAETLNFADFNIIYVGQS-EEVKCSTGLV----------------------IGELSPLPEV-IPSGSLVVLPGVSDSL-DNKAAEATIKWVKKLKPQELSIVCICSGALLAAKA-------GLLDNRKCTTHHEILDRL-------------------RDLLAKVKE-----NLLFIEDKGVFTCAGIMAGIDLALSLVR---------- +------------------------FVELLDLAGPLQVFTEARVRLEFYSYQ-PESVSSAGLP----------------------MGKVSDYREAALGEGDFLFLPGMEFEYSFR-GEADFFSWVRQTADRQVTVCSVCNAAYVLGEA-------GLLDQRECTTHWRRVKDL-------------------QDRRAKVIG-----DVLFVKQDNIYTSAGISAGIDLALSVLE---------- +------------------------RVHILDLAAPAQIFAH-PLELHYISPC-PEVSSKQGLH----------------------LAQLEPLPHN-IEPDDWLLLIGTSRLD-HEAAYQQSINWLSTVGADFALLAGICSGTILAGKA-------GLLDGRRCTTHHDLTHSL-------------------GQIRAQVQE-----DCIFVADENIWTSAGITTGLDLCLQLVA---------- +------------------------DTLPLDFAGPLQAFLEARFDIKYVSAS-DQLICDGGLQ----------------------LQNLTPLPEK-LEADDIIVIPGCHHAF-STEASLQTIQWLKNTI--HQAILTICSGAVLAAKA-------GLLSHRTYTTHFHLIEKM-------------------RQAECVALE-----NRIFVEDNNIISSAGISSGIDMAIYFIA---------- +------------------------DTLPLDLAGPLQVLLEAQIDIHYVSAE-DTQIMDGGLR----------------------LHQLKPLPAK-LNATDVVILPGCNDAF-NNPAGLRTQQWLKAQAR-DPYILSICSGAVLAAKA-------GLMENKACTTHFALIERF-------------------RSTACKVAD-----NRIFVQDGKLFSSAGISSGIDMTLHFVS---------- +------------------------GFLPLDLAGPLQVLLTANYNIHYLGVE-PSPAMKGGLL----------------------LQNLQSLPEQ-FPASSRLIIPGLSGTD-QSTLGIKTTDWLRQQRQVGLEVATVCSGALLAASA-------GWLSNRHCTTHHDLLSRL-------------------QSLSAEIAS-----NRLFVQDSKLWTSAGISSGIDMFLAMLQ---------- +------------------------DTHLLDLSGPAQALRTLSVEMIFFSPS-PSVVSYQGVT----------------------LSGLASLPAE-DIVFDLLIVNGSKYKE-SDKESQQGLMWLQNYAQRQAAIASVCTGAFYLARA-------GLLRNRHCTTHHGHVDSL-------------------KLASATVLE-----NRLYVRDGPIITSAGVTTGADMILAWMA---------- +------------------------NVLMLDLAGPAEVLRLASFELQYVSPL-ADLQTSIGLP----------------------LAGLAPLPET-LLPGTLVVLVGSISAQ-FEASSAVLTQWLRQVLAPGERLLCVCAGALSAARA-------GLLDGRQCTTHHSLCAKL-------------------QELKARVLE-----NRLYVTDGRISTSAGITAGIDLMLQVLA---------- +------------------------GVLMLDYAGPAEALRMAALLLHHCAPV-PRLATSLTVE----------------------IGGLRPLPPE-LPPHSLLIVTGNACEA-ARPEAHAVIDWLRHAPRA-TAIASICSGALLLAAA-------GLLEHRQCTTHHSLIDDL-------------------RALTARVQE-----NRVFVEDGPLLTSAGITTGIDLALYLIE---------- +------------------------GQVPLDLVGPLQVLQCADVEVCYVGPK-TAMPWLGPLT----------------------LSGIDPLPEQ-LPPQQLLLIPGQY--R-EPLAQQECVSWLKANACYADTLMTVCSGTLLLADA-------GLLEGRRCTTHHTLIEQL-------------------QTKKARVQS-----DCIFIEDGRYLTSAGISTGIDTMLYWLT---------- +------------------------RALLLDIAGPMEVLRRANFVPTYIGPA-AEVRSSTGLD----------------------LARISPHPAR-LPDDALLVVSGAVDEPEDAALEAEIVEWLRGIVRPGIRLATICSGALLAARA-------GLLEGHECTTHHSMLQDL-------------------VRLTARVRE-----NRLYVEDGERLTSAGVTAGIDLMLAVVA---------- +------------------------HSLVLDWAGPAEALRITNFVLHFASPT-PQSVTSVGAV----------------------LSGLEPLPTA-WPAAAWVVLIGLPGAA-ATEEARALLHWLRGLR--RLELLTICAGSVLAAHA-------GLLAGRRATTHHQHLAEL-------------------QQVHCDVVA-----NRVFVPDAPLYSSAGVTTGIDLVLHRIA---------- +------------------------NSLALDWAGPAEALRTANFQLEFIGPV-SDPISSVGLG----------------------LRDVKPLPDLGA-PPVWVVLLGQPGTT-RSAHSRATLHWLRRLR--RLELVCICAGSVLAAHA-------GLLAGAEATTHHHHLAEL-------------------QAADCHVLS-----NRVFISSGAICSSAGVTTGIDLMLHRIA---------- +------------------------QVTLMDVTGPWEVFCRAEYDVAVVA-E--ARVTKFGLD----------------------IRCEH-SVHEGA--LDTVLVAGSQ----A--ADPAFLAWLQD-AR-TRRMGSVCTGVFYLAQA-------GLLAGRRVTSHWRYINQL-------------------KTQDLTVDP-----EPIFVAD-DIYTSAGIAAGIDLALALVE---------- +------------------------QTVCSSLSVACDAFALANFNLQRCSLDAR-PVLG-FAR----------------------IQV-DGGLEL-AS-ADLLIIPATGSAI---CANAALITWLAQRPA-SQQIASLCSSAFLIAAA-------GLLDGHRATTHWALARQF-------------------RQRQVNLEI-----AELLCHDGNLLSSGGAQAGLDLCLYLIT---------- +------------------------GIPSTVISGLLEFFELARVGLKTVSLQSG-PILNAGLS----------------------IEA-DVIGRI-AQ-LDLLLIPAIGMNT---ERFGMEVELLRELSSKGTRLASICSGAFLLAET-------GLLSGKAATTHWRLASKF-------------------RRRDVDLQI-----DRMVVDAGSVLTSGGSNAFYDLALYLIE---------- +------------------------PFKLLDLVGPLQVFSDANYETIVLS-E--A-KTDTV------------------------LSPDTQALSEP---FDTTLVIGNE----I--EDRKTVTS---AAN-SKRVGSVCIGAFALARV-------NMLNGLRAVTHWKYCDLL-------------------AQSEIRVEK-----DPIYIRE-AIWTSGGVTSAIDMALAMVA---------- +------------------------DCQILDVTGPLQVFASANYEILILGPK--P-VTNSGMR----------------------LLPDYGYDEA----LDTLLIAGGR----K---NDVLLAWLKAQEN-VRRLGSVCSGAFLLAEA-------GLLKGKKVATHWRCSQLL-------------------AKEGLEVDD-----DAIWIKQ-HLFTSAGVTSGIDLALALVE---------- +------------------------GVQLLDVAGPFDAFAEANYQPVLMSLE-GKHLSSSGVA----------------------LNANARLTD--FSPNVSFLIAGAPDID---ALTERQIAAVTALCRQSVRYGSVCTGALLLAQT-------GLLHQRQVATHWSVAEQL-------------------ARRDIAVDA-----DALYVADGPVRTAAGVTSGMDLALRFIE---------- +------------------------GVQLMDIAGPADVFAEANYRPVI-A-R---NICSSGFS----------------------LRAGLLLSDVT---VDTLLVAGAP----A--SDPVLTSWLRLEAR-ARRFGSICGGVFPLAET-------GLLDGHTIAAHWADVDCV-------------------CQRAVTVDA-----DAIVREE-ALRTAAGVSSGLDLALSLVR---------- +------------------------GGMLFESAGIADILMQANYQVKLATTQ--QVIGQSGLN----------------------LLADHRLHEIP---LDTIMITGRG----Q--EGMAVVDWLRLAAH-ARRIVSICGGAMLLAQT-------GLLDGRRATTHWKLLETM-------------------QAEQIRVEG-----GPLYIQD-HIWTSGGVSSGFDLTLALVE---------- +------------------------GAQLIGIIGFIEAFDAVNYEVLVCG-D--Q-TSVTGLG----------------------LATR---PAARR--VDTLVVGGAL----D--REPELRRQVAR-LR-ADRVVAICGGAFVLGEL-------GWLEGRRCTCHWMDLDNL-------------------RARTAEVQT-----DALFTED-GVFTSAGASAGIDLALHLIR---------- +------------------------GFKLMEAVGPVSVLSYANYRIDLVA-T--A-ISDTLIS----------------------LDVSAGLPERD---LSTVLIAGAL----A--RETALVDWVRRRSA-ARRFAALCSGSFFLATA-------GVLSGRRAATHWSVATLL-------------------QQRSVEVDA-----DAIFIQE-NIWTSAGVTAAIDLTLAFVE---------- +------------------------TAQHLDIAGPADVFAMAGYRVVVLS-A---PILSNGLT----------------------LHTEA-AASVAS--VDTLIIAGGE----G--ADQALRAWLDQ-AR-VRRLASVCTGAFLLAHW-------GMLAGRRVATHWRSAQLL-------------------AGHDLDVDP-----DALYVQD-RLWTSGGVTAGIDMCLAMVE---------- +------------------------DSQVLDISGPVTVFEGANYDVSLISPGGG-PVTNGCIA----------------------IQAHGSVESEDLE-VDTLLIPGGSKGT-QAMRDPALRRLVRRANDKQIRLMSICTGAFVLAEA-------GILDNRQCTTHWAEIGNF-------------------RRLGVTVLT-----DVIYHTEDNIWTSAGVATGIDMALAIVA---------- +------------------------NATLLDITGPYEAFSLATTYKLHTL-I--N-KVRTSSG----------------------LCLLCENSIKL---IDTLFIPGIP----M--VDAKTLSWIKRQSK-VRRICSVCTGAFILAEA-------SILENRNVATHWKLCNQL-------------------AESTLKVDN-----ESIFIKD-HVYTSAGVSSGIDLALALIE---------- +------------------------DCQMLDVSGPWQVFASANYRLRLIG-S--E-LTNGGLR----------------------LLPDLDWEGWDAGGLTTLLIAGGH----Q---QQRWRERLTRVAH-LGRLGAVCTGAFLLADA-------GLLDGRSATTHWRHCRRL-------------------ADDQVRVQA-----DALYVHD-GRYTSAGVTAGIDLALSLVE---------- +------------------------QFELLDLSGPSSVFNAAKYEIHVLSAAGG-LISRTGIE----------------------VNSQ-SLATFDVR-SDTILVVGGSQKA-QVSVDDVVQNWLAKNAEKAERVGSICTGAMVLAAN-------GLLDEKRATTHWADLSLM-------------------ADKCVDVAK-----DALYCVDGNIWTSAGVTTGIDMAMAMVG---------- +------------------------QFELLDLSGPSSVFNAAQYSIHTLSAAGG-LVSRSGIE----------------------VNSQ-TFEGFSVC-SDTILVVGGAKQA-KVSLDLNLQTWLMINTPKAERVGSICSGALILAAN-------SLLDDKKATTHWADLEQL-------------------ARDSVNVEP-----DALYCVDGNIWTSAGVTTGIDMALAIVG---------- +------------------------RTKLLDVAGPLQVFSDA-YQVSLVS-G--S-VTDTGFA----------------------LASDP-CETCR---PDTLIVSGGD----H---DTRLLSFLAEMAR-CRRFGSVCLGAFILAQG-------GHLNGRRATTHWENCAQL-------------------RQRQIDVRD-----DSIFETD-GVWTSAGVTAGIDMALAMVE---------- +------------------------DVLLLDVTGPMDAFAIANYRLITLADG---VVGSCGLR----------------------VIADLRLEAL----VDLLLVPGGP----A--L-PGLEHWLTQAVG-AKRFGAICTGVFLLGRA-------GLLGGYRCTTHWNYVERL-------------------ARAEAKVET-----EQIYVID-CLITSGGITAGIDLALAVVA---------- +------------------------GFKALEAIGPMSVFDYANYVVRVVA-Q--L-VSDTLMG----------------------LQASHTLAQVA---GCTVLLVGAR----A--ASPELVDWVARVAG-VGRMIALCSGSFFLAAA-------GLLNDRRAATHWSVAGAL-------------------AQRRVQVDA-----DAIYVCD-QLWTSAGVTAGIDLALAVVE---------- +------------------------PIDLFNVVGPMEAFRLANYQIELVSTRADLAISETGIN----------------------LQAHYSLSD--ERWIDTLIITSN-ILL---GNPPDAIKWINTQTKNARRICSLCGGIFALAQT-------GMLNGKRVTTHWRVVEQF-------------------AQQQIKVDD-----QPVWVKDGNIYTSAGMSASIDMALSLIA---------- +------------------------ECQVSAIHGLRDIFRVASIRVSTWAVSA----DDGPVM----------------------VCTSDTHPEL-AH-LSHVVIPPSLVVP----SAGEFTDWLVGLRSEGTTLCAVCAGVFVLAET-------HLLDCRDATTHWAFAEEL-------------------ARRKVRVDA-----SRMVIDDVDIMTAAGILAWVDLGLTVVD---------- +------------------------DMQALDLVGPLDVFGAANYRLCVIGLS--S-VAENGLL----------------------VVPEHTLEDA----LDTLLIPGGM----S--GDARLLGWLSERAL-TRRVVSVCTGLYILAAT-------GLLDGRAVTTHWRYADDA-------------------ARRDLRIQP-----DRLFLRD-RFATAGGLTAGIDLALALVE---------- +------------------------GVVLADVIGAADVFGVGDYAISLLSLNGG-VISSTCVQ----------------------IMTLPLPPHDNH--FDTLLIASGT--G-DAYRDPGLIGWLQDVRNNVRRIGAVCTGVFVMAAA-------GLLDNRRATTHWALQDKL-------------------IREQIKIER-----DATSTEDDGIYTASDVGMATDLALTFLE---------- +------------------------EVMPSAVQGVKDLFQIANVRELAYQSS-------------------------------------ESVDG-----DALIFIPPCLSAD----QTEAVITLIREWHRAGAVIVSSCASVFWLANA-------GLLDGKYATTHWRLCDQL-------------------ERDSISVCA-----HEMLVDEGDIVTAAGLYAFQDLALHVMA---------- +------------------------GALPAAIAGTEDLFRLANLQVVDPSGA-------------------------------------SSLPH-----AQVVILPPFIDDR----ADAQVIARLQALQGTGTLIAACCASVFWLAEA-------GLLTGRTVTTHWALFDRL--------------------RQGIKVDQ-----RNLVVDQGDIVTGGGLFAFQDLVLHLVS---------- +------------------------GALASAVLGLVDILTHAGMTAAD----------------------------------------WANMPG-----ASAILLPPAATAP----AHPDLPRWIADQAQQGALICSACVGVIWVAAA-------GLDAGRPVTTHWGAGHNL-------------------QRHDLQINT-----DRLVIEYDDLVTAGGLMAWVDLARIVIE---------- +------------------------TASQSAVHGFAETMMLANFDVGINTLEQL-D--------------------------------------I-ER-AKVVVLPPCIND----QHNTALNQYLLKMQQQGAVLASACVGAFILARG-------GFLDNKFCTTHWRLGESF-------------------RSARAKLND-----NAIIVNEGNIITAGGRMAWLDLVFEIIS---------- +------------------------GSLQSAVFGVKEFLQMANFQVEIKPCGDL-SV--------------------------------LSANSNEES-ADIILLPPNLDG----ERDDRLTDYLIESHQKGSILCSACAGVFILAQT-------GLLEGRTVTTHWQAQQLF-------------------SELGIDVDI-----DKILIDDDDIITAGGLMSWMDLALFILT---------- +------------------------NSLRSAVYGLEELFAMANFKAEIIAFDTE-SSEKA--------------------------KLDNSLPDERDA-YAVVILPPSQLG----TPPQALIEWLGKQHQQGSILASACAGAFILART-------GLLTGKPVTTHWGLAQAL-------------------HQQELQMAT-----DKILVNQGDVITAGGMMSWLDLGLEVVS---------- +------------------------GTALSAVYGLIDLFQSANFSVSRWQLDE--------QV----------------------I----SMDPG-AV-PALVIVPPILDGQ----PQPIIGAQLATWHRQGVVISSACAGAFFLAQA-------GLLEGRRATTHWQLESAF-------------------RCATIELDT-----DALLITDPDLVTAGGVMSWMDLGLHLIG---------- +------------------------HVLASSIIGIIDIFSITNFEVTVIDIDQT-AKFNTTIT-----------------------FP-SIQPDK-SQ-YDLIIVPPIINLE----VSENLISWIRAMYQKGSYVCSVCIGAYILAGA-------GLLTGKKATTHWAVESKL-------------------RSEEIDLQI-----DKIIIEDDNIITSGGVSTYVDLCLYIIR---------- +------------------------GVQWAAVYGLTDLVLTANICVSHWSIEG----GA--LP----------------------IRTYQSFDHD-AG-VAALVVPPTLEAP----LAAPYLDWLRQKHSAGTVLSSVCAGTFLLAQT-------GLLDGRAATTHWMHAKAF-------------------RNRKVRLDV-----EQLLLDEGDVLTAGGVMAWTDLGLRLVE---------- +------------------------DVQMLDVAGPSEVFAMAAYAISVLS-R---EISSSGMR----------------------LMTTA-LAAADM--FDVVLVAGGQ----G--ADRELLAWLQS-AH-ARRIGSVCTGAFVIGAA-------GLLDGYRAVTHWKSQEAL-------------------ARRRAQIVD-----NVLFVVD-QRVSSAGVTAGMDLALHLVE---------- +------------------------DVNLLDVSGPVQAFDTARYDIRYVSLNGR-PVAGCGLR----------------------MVPDAALSS--ESTNDDLLIPGGAGIN---IPNSTVCEIVALERKPNGRVISICSGALLLAAA-------GVLDGRLATTHWSRLAD--------------------IKTRVLWDL-----DQISTAQDRVFTSAGVTTGIDLALSIIR---------- +------------------------NFQALDLAGPLDVFAEANYEIVVIG-T---ILASNGMQ----------------------LVPDICVGAAG---YETILVVGGP----Q--PDKRLVSYLCEQAH-VRRYGSICTGAFYLGAA-------GLLNGKKATTHWQAAPLL-------------------AKKSVSIDP-----DPLFIYD-PLITSAGVTAGIDLALALVQ---------- +------------------------GVQALDVSGPMDVFAEANYEIEVIGIG--ALVCSNGLL----------------------LKVHRAYAD--VDPFDLMLAAGGP----V--WEAGAYDWLRRVCA-SRRYGSICNGAFALARA-------GLLDDRTVTTHWNDAEAL-------------------RHLTTRVEA-----DRIFVRD-ELYTSAGVTAGIDLSLYLLA---------- +------------------------GVQALDIAGALDVFSEANYQVSLVGERAG-HICSNSMQ----------------------LSVPFDYTAFQT--VDVLLVTGRP--H-NSRPKREFLDWLRDRAFQSKRIGSICNGAFLLGHA-------GVLNGREVTASWADASSL-------------------ARELARIRP-----DKVLIRDGNLVSSAGATAGWHLCLSQVA---------- +------------------------GFQLLDIAGPKDAFAEVKYEMMMVG-T--T-VSSSGLT----------------------TVPDRTIFDPS---FDTIIVPGGL----F--DDPALSDWLRAQHQ-CRHVSAICNGLFALGSA-------GLLDNKLVTTHWMDVPRL-------------------ASTKARIEL-----DHIFVRD-SIYTTAGVTAGIDLSLAMIE---------- +------------------------QFQSLALS-TLTVFEFANYSCTVYSES---KVSSYGLS----------------------IIS-RKL--TDE--ADTWLVGGVL----PA-T-DGIISFLQNQAH-ARRVAGICTGAFVLAQA-------GLLSERRATTHWAYAQSM-------------------KILAVRTED-----DLIYIID-RIWTSAGMTAGLDMVLAMVE---------- +------------------------GFQVMGLA-TQTVFEYANYALRNFSVA---DVSSLGMS----------------------IAT-LPV--EQA--IDSWMVCGVG----PS-S-QEERSFLQTTGR-ARRIAAICTGGFVLAES-------GLLSKRRATTHWFFARDM-------------------QARDIQVED-----DRIYIVD-AIWTSAGMTAGLDMALAMVG---------- +------------------------DFNLLDFAGPLTAFDTVSYQCRALSVE---LISTPGIE----------------------VMT-QPIV-AGL--FDTLIIAGGR----M--NNPSLLDFLRDQHQ-GRRVTSVCSGAFILAAT-------GLLDQQRVTTHWSQARRL-------------------QQCAIKVDQ-----DRIFIQQ-RLWTSAGITAGIDLALAMIE---------- +------------------------DFNLLDLSGPLCVFETANYTLDICS-C---EISSCGAV----------------------MRTTS-FKEK----FDTLIVVGGR----S--NDQAIHAVLNS-G--ASRYVSVCTGAFILAAA-------GILSGKRATTHWARAPEL-------------------KRMDIQLMP-----DEIVVED-NVWTSAGATAGMDIALALTE---------- +------------------------GFVLLDLSGPLEAFSNANYRFTVASLEGG-LIASSGLQ----------------------VATEALQVVDQLE---RLRIESAR---------PLVEDGLQTFEEI-----ARCFGF-------------------------GDADHM-------------------LRSRVVGRT-----PQELRRSARQAKGNGSGKNADPSPA------------- +------------------------QFQVMSLL-ALSVFDIANYEVSVISED---PVASFGMS----------------------AST-EPA--RL---LHTVFVGASL----PPRVTDSMRELLLELSK-VERLASICLGAFLLADT-------GLLDGRRATTHWAFLDRF-------------------QNGAVTVER-----DCIFVRD-NVWSSAGMSTAIDMALAMLE---------- +------------------------GANTIDFMGPIDAFNEAGYKVDLIG-A---LIGSSGVR----------------------IVPDK-VIGSDT--YDTILVAGSQ----D--NNQPLIDWLTR-AS-ARRICATCAGTFVLASA-------GLLDGRRVATHRNYTRQF-------------------AARQVHMEP-----DRLFAHD-LYYTAVGGMAGIDLCLYLIE---------- +------------------------SVTMIDVAGPADVFHHANNDTVLVS-D--A-KASNGHY----------------------LTAE--AAAGGA--LDTVIVPGAY----P--FEEGLVEAVSH-LD-AGRIASVCTGAFLLAHG-------GLLNYRNATTHWTQVERF-------------------RRSLVHVVP-----DALFVQD-SIITSAGISSGVDLALFMVE---------- +------------------------SVHLLDLAGAVTVFYES-YDMRYVSPY-HHPETSSGLG----------------------FTNVEPLSSVTVHQNDIVIVAGMEIDK--RADDQLWIPWLQAAAKSAAIVASVCTAAFALAAA-------GLLNGQNCTTHWAWTTTL-------------------QKRLIKVIE-----NKLFVQSGRIFTSAGIATGIDLALYLIE---------- +------------------------HVHLMDLAGAVTVFYEA-YELRYVSPY-PSIGSSAGLG----------------------FTKVEPLEAVVVQPEDIVIVAGIDLSK--HTADDQWLHWLQHAAAIGATVCSVCTAAFVLAVA-------GLLNGRDCTTHWGYTKAL-------------------AQRRTNVIE-----NKLFVKSDNIYTSAGISTGIDLALYLVE---------- +------------------------GMELLDMVGSQTAFFEGNYRLTVVGFS-DRPVSEAGTQ----------------------IVPDCGLDS--LDECHTLVIPGGKGAR---AFPEVALQKLKKLIVRSERIVSICTGAFLLAKT-------GLPEGTKMATHWAFVKDL-------------------KKQKLVVDG-----DSLYIQDGKYWSSAGVTSCIDLTLRLIE---------- +------------------------GMELLDFAGPQSAFYEAQYQLKVVGFD-ENAVCEAGLL----------------------ITPAISLSE--ITACHTLIVPGGKGAR---TVTSTQLEGLKQLMSRSERVASICTGAYLLARA-------GLPQNTKVATHWAFVNHL-------------------QQELLNIER-----EKLFVDDDKYWSSAGVTSGIDLTLRLIE---------- +------------------------GFHILDLS-VLTILGIANYAVDIVSMR---NITRSGVP----------------------IGT-QAI--DD---YDTLLVASTP----CP----GLLDRLRQAED-SRRIAGICTAAFLLAEA-------GLLDGRAVTTHWSFADTL-------------------ATRQLRVQP-----DQIYVRD-KFWSSAGMTAGIDMVLGLVE---------- +------------------------GCMHSAISGVADVLSLANFTWKTLSLDGK-AVAGGGQT----------------------VAV-DGAIGK-RA-FDAILVPGNLVDH-R-PQYVRAGAWLRQQHANGRLIGAFCSGVFLLAGA-------GLLDNRRATITWWLQSEL-------------------RQRAIDLAP-----DAVITSADRVVCAAGPMSWVDLLLRLIE---------- +------------------------NCMVTGVAGPLEIFSIANAGLNIVAIGGG-DAGFAGIA----------------------VAV-SQDLS--CV-PDILIIPPVFGDL---D-DEILIAQLSRLVSQGTIIATTCAGSFLLAQT-------GALSGKTATTHWNLVAEF-------------------AERDIDLQA-----RQMLIDGGNYICAGGAMAWQDLALHIVA---------- +------------------------NFLGLAAFGSADMYETANFAVKTYSLDGQ-PVSSNGIL----------------------VTP-DGSLKD-IT-PDVVFLPGIGTAT-NTSWFQGVAETLQRLSQGGAIVAASCTGTFLLAEA-------GLLDGKKATTTWWKQKEF-------------------SSADVELDG-----DEILIDAGNVITSAAGTSALDLALYLIK---------- +------------------------HFTLSPFALFVDTLRLAGFDWQVVGERGL-PIASCGIE----------------------VMPTRELQH--PE-YDDIVVVGGLLNT---TLGSQKEAFLLKAASRGVRLTALCTASFVLARY-------GLLDGYNVSVSWLHVKDF-------------------RTMQVLAHA-----DSLFSVDRSRATCAGGVGAADLAGHFVA---------- +------------------------SFTLSAFSLFVDALRLGSCDWEVLGSTRN-FVSSCGIQ----------------------VAPTAPLRP--PS-FSYIAVVGGRLNV---PLDRETIDYLHRAARAGVPIIGVCTGSFVLAEA-------GVLDGHAACVSWLHHNEF-------------------RARAIEVTS-----NRIFVEDAKIITCAGGSSVADLATYLIR---------- +------------------------RFQVLDLAGPMQVFLSASYRVSVVS-G---RVGSLSLA----------------------IDAEP-LPSAP---GTTVMVVGGR----S--QDLVLIDWLRR-HE-AERICSVCNGAIVLARA-------GLLAGKRATTHWVDCDKL-------------------QRNDVTVDR-----DAIYVRD-KIWSSAGVSAGIDLALALLA---------- +------------------------GISLLDLAGPLDVFIAANYSLSIFSLS--S-EF-ADFS----------------------LNA-APLESET---PHTLIVPGGP----C--AQPKFLTHFVKHTK-AKRLVSVCTGVFALANA-------GKLDGRNVTTHWSAYERL-------------------EHETAKVRR-----GPIFIND-DLWTSAGVTSGIDLALAIVE---------- +------------------------QANLIDLAGPLEVFSTANYHLSMVSLD--A-AL-PDTY----------------------IHT-ALLDESS---PHTLIVPGGL----C--KHPQFSAVFKAHVK-VTRLVSVCTGVFGLGAA-------GALSGCKVTTHWSAYDEL-------------------EKTDVLLRR-----GPIFVND-RIWTSAGVTSGIDLALALVE---------- +------------------------GCFGAEIFGITDLLRIANFEVSVVARRGA-LVVAGGIS----------------------VGARQWHPGL-----DTL-VVPGFELA----LTGSLARWLSLVAARGVPVASVCVGAFLLGEA-------GLLDGRTVTTSWLFAREL-------------------AARRATVDA-----DAMMVADGNVTTTAAFSTVHDLAMHLVT---------- +------------------------GFELLDVSGPASVFNGANYKVGLVS-K---GISSSGIV----------------------VDTMP-IADLGDNQDQTILVAGAE----L--ADPALRSALPA-CT-AGRFGSVCSGGFLLATL-------GLLDGHRVASHWDACKPL-------------------AESAVTVDP-----DALYVVD-RLWTSAGVTTGIDMALAMIA---------- +------------------------GVTMLDLSGPAEVLHAAEYELMYVS-A--D-VTSANMV----------------------IARTI-ADHVTG--LDTVIICGAD----Q--INQEVIEAARY-LC-SGRVVSICTGAFILAEL-------GILDHRRATTHWRHASTL-------------------ARRNVAVER-----DVIFVHD-KVFTSAGVSAGMDLALHLVE---------- +------------------------GVRALDLAGPTEVFEIARYTTGLYSTANSPTVCASGMT----------------------VHATAAS-A--LTNADTLLVPGGDDPA---AAP-WLSKVLRAQLNDVRRIAALGTGCFALAAA-------GILDGRRTTTHWRHLDAF-------------------AARTAVLDR-----ESAFTRDGPVWTSAGASAGVDLALALVG---------- +------------------------GMPIFEAAVPCQVFGVDRYDFSVVP-G--P-VLTMGFS----------------------VATA--GTGWDA--IDTLVVPACT----E--QPAELVEVVRQ-AR-GIRILSICSGAFILAAA-------GVLDGRRATTHWLYAEQL-------------------ASRAVRVDP-----SVLYVED-NVITSAGTVAGIDACLHVVR---------- +------------------------GMSPFELGCVVEIFGIPRYELRVCAET-PADLIVGGFT----------------------MRAEHGLGV--VAEADTVIVPGVPDVS--GTVSPELVATLRAAHARGARMVSICSGAFALAQA-------GLLDGREATTHWKYAELL-------------------RHRRVRVNP-----DVLYVDGDDVLTSAGSAAGLDLLIHLVR---------- +------------------------DMLILDLAGPMDAFRLAKYDVVIAS-M--LYLNFNGLN----------------------FSCDK-KVVDEP--IDTLIISGFS-------DYLIFQEWLQK-NK-IRRVCSVCIGAFLLAGS-------GLLNGKHATTHWMYCDLL-------------------KKKLIQVES-----KPIYIQQ-SIYTAAGASTGIDLCLALIE---------- +------------------------DVASLDISGPADVFHLARYEVVIAS-T--H-ICSNGMT----------------------I-DTVDLRGIA---IDTLIVPGGG----P--VPLDAVAWLAHHGD-ARRVCSVCTGAFLLAEA-------GLADGRRLATHWQAGEEL-------------------AARRIEVER-----DLLFVAD-DIWSSAGFTAGIDLSLALIE---------- +------------------------DVDLLDVTGPPEVFSLARYDVVLAAET--P-VTGAGVR----------------------VLPDVTFDELS---IDTLIVPGAVEVD-R--TDPAVVDRVRQLAR-TRRVTSVCVGAHILAAA-------GLLDGKRATTHWSTAQQL-------------------AADAVEVDA-----DPIFIRE-DVWTGAGISACLDLSLALIA---------- +------------------------AAELVDIACVTSALVMANYDVTVAT-G--P-ICGSGLT----------------------LQAQATLERLN---LDTVLVSGGI--------DHRLVAHVRRLAE-SRRVASVCTGAGVLAAA-------GLLDGRRAATHWFQADDL-------------------AATAVCFDS-----EPIYVRD-NVVTSAGVTSALDLTLAFIE---------- +------------------------GVQSLDVTGPMEVFTGASYRVRTASLD--P-VTSSGLT----------------------LVPDTSLAELAGFAPHTLLVPGGAGT--A--ED-ELVAWLRAHAR-ARRLVSVCTGAVLLARA-------GLLDGRRATTHWAYCDTL-------------------ARDEIDVDP-----DPIYVRD-HVATSAGVTAGIDLALALVE---------- +------------------------QFQLLDVSGPLQVFATANYETGVYG-E--A-TSSSGVE----------------------V-LARPLPKRS--RVQTLVVPGGP----P--AAAALARWIRLASR-IERLASVCTGAFVLAHT-------GVLDGAGAVTHWAACEHL-------------------SSRAVAVQP-----DAIYFRQ-RVWTSAGVTAGIDMALGMVE---------- +------------------------GFELLDLTGPYAVLSSAAWSLCIAA-E---LVSGHGVA----------------------VLAEH-ALQEAT--LHSLICVGGD----L--SDQDFLDRLRR-TA-AERCISICSGAYLLAEA-------GLARHHRLTTHWRAVRHL-------------------SERDIKVEP-----DAIYIQD-AIWSSAGVTAGMDLALALVE---------- +-------------------------MKTLDFVGPAEVFTEANYDVRFFSHDGRDVVTSMGLR----------------------VGVDAAAAD--SGPLDLVIVPGSESAP---YRPDEVQAAVRLLASRADRVASICSGAFALAVT-------GLLDGKSATTHWKFTGAL-------------------AAASIDVRP-----DSIFVRDGDTYSSAGVAAGIDLALAIVE---------- +------------------------GLKPSCLFNAIEVFEKANFEIRLTGTNLQ-QRANGLFS----------------------LQV-AP-LAA-ID-AGIIILPSFT-EQ----KNRAALDWVISQFNGGAEVASLCTGTFLLAAT-------GLLNGKPCATHWKAAAYF-------------------QRLELELHT-----NKILTDQQGVYTAGGALSSVNLALYIVE---------- +------------------------QVNLAGLDNARQGLLEANFEVEVVGVQSS-VTNKGLFS----------------------INS-QKQISH-LV-TDLIIIPPVQ-SP----KNMAFIPWIRSQRQKGAEIVSLCMGAFILART-------GLLDDRDCVTHWKAGDAF-------------------KSLKVNLVS-----EKILTDHDGLYTGGGAFSSVNLILYLIE---------- +------------------------GTSLSSMEATYKMFSKINFDIQIVGLSDE-AVSGRIFS----------------------IRS-DTTIHQ-LK-TDLIVIPAIH-GN----VNREFVPWIQKQYQLGAEIASLCVGAFLLAST-------GLLNGRSCTTHWLSANEF-------------------SSMHVKLMP-----YKVITDERGIYTSGGAYSSLNLILYLVE---------- +------------------------NVLASSVMGTMDTFGQTGFDINIVTQDGK-PVTRHQAA----------------------IYP-NGSIQ--DI-STDLIMISSFSDY----TSGKAIEWLREQNKKGTTIAGICAGAYILAET-------GLLNGKTATTHWGFANDF-------------------RKRQINLQS-----EKIITDEGNLLCSGGCNSYIDLSIYLIE---------- +------------------------GVFASTLMQAKDFFHMASLETWLVSPDGN-PVTFNGSR----------------------IEV-EGSLG--ET-AV--ILPAFWGDF---QQYPQVEPWLQERHAAGTAICGEASGVFWMAAA-------GLLDEREATTHWRFAKEF-------------------SERRVLLTL-----EKHLTDSDNLYCAGGTTSSCDLYMHLVE---------- +------------------------GAWASTVYGSMELFHSVNFHCDLVSADSQ-PVLYGGQS----------------------IQG-DAVIG--DE-YDLIMLAHYWGDF---EQYPSIPPWLAKQHAKGARIAGVNSGIFWAAEA-------GLLDGGRATTYWRHLREF-------------------ELRKVQWQA-----NQASVEHARIYSSNGQNASMDLSLHLVE---------- +------------------------GAWASTVFSSLELFHSANFHCDLLSSDNQ-PVLYGGHS----------------------ING-DTMIG--EQ-YDLIILAHYWGDF---QQHPEIPPWLAQQYAQGARIAGINSGIFWAAEA-------GILNGGRATTYWRHLREF-------------------EQRDIQWQA-----NQASVEHAGIYSSNGQNASMDLSLHLLE---------- +------------------------GANIASLETARQGFQAANFSVRLLAAEPT-MSDEGRIT----------------------VRA-DATLAQ-PG-VDICLVPPLM-AP-AVAANTALIQWLCAHYREGGELANLCLGAALPAAG-------GLLDGRRAVVHWVVRNQY-------------------AALKVSWIC-----DRVVLAERGLYTSGGAFSAAHLVLHLIE---------- +------------------------NGVIEAITPAVRIFQTANFKVELTGLKKT-ITSEGPYT----------------------ITV-DRLLKD-VS-ADLFIVPALLHPS----ANSAAFPQLTALHAKGTEMASLCLGAFLLAAT-------GVLDGKKCSTHWAYYNEF-------------------MQLQVTIAS-----GSVITDEAGVYSSGGANSIWNLLLYLVE---------- +------------------------GFQPIDLAGPWQAFTTANYRLTTMAQK--DAVSDGALK----------------------IHVDHGLGAAA---IDALVVPGGG----C--ADLQLVDWLRERDA-TRRTCSVCTGAFLLAAA-------GLLNGREVTTHWRSAGRL-------------------QRDDLRVND-----DKIYCES-KYWTTAGVTAGIDLALALIE---------- +------------------------GFQALDLVGPMEVFSLAVYECHLLS-Q----LTSSGMT----------------------LTTKK---LIEG--FDSLILIGGQ----G--QQQYLIQYIQE-QR-VKRIVSICTGAFLLARA-------GLLAHKKITTHWSCIEEL-------------------QALSAEVIE-----DAIYIKS-NIYTSAGISAGMDLALSLIE---------- +------------------------GFQPLDLAGPWQAFSGANYQLSTVAAT--PVVTDQGLR----------------------MQVNATFASDD---IDMLFVPGGP----A--AHGETLAWLRRRSQ-ARRTCSVCTGAFLLAAA-------GLLDGRRVTTHWRSADRL-------------------RQRGLKVED-----DRIYIES-AIWTSAGVTAGIDLALALIE---------- +------------------------DVMSLDVTGPLQVFASANYRIQVLGERSE-AVSSAGIR----------------------ICADLAWRDCPPE-LDTLLVPGGLGVE---TRNADLLAWLKAAEPRIRRLGSVCSGALILAAA-------GVLDGHPATTHWADVATL-------------------RQGGVHVQG-----DRLHTYDPHIFTSAGVTAGIDLVLRRPV---------- +------------------------GSELLDIACVTSALAIANYRTVLAT-G--P-VCDSGLR----------------------LDAGAELERIN---LDTLLVTGGN--------SPIVVGHVRRLAL-ARRIASVCTGSTVLAAA-------GLLTGRRATTHWRYAAEL-------------------AARDVLVDA-----EPVWIRD-RVATSGGVTSALDLTLAFIE---------- +------------------------GFQALDLFGPLDAFMETNYDCKLLSIE-AGAVTVYGQQ----------------------VQADFGLDD--EFAVDDLIICGGNGMR---SLSAAQLSALSALAAGARRVFSICTGAFVLAQL-------FPQQALTLTTHWRHCESL-------------------ARQHCTVSP-----DPLYIQDEHIWSSAGVLSGVDLALAIVR---------- +------------------------DFQIQDLTGPLAAFEVAGYRYQVISLA---PVSSAGLE----------------------VTT-QRA--GF---YDTVIVAGAG----DAALPETCDYLNHVVAG-ARRIASVCTGAFILAAS-------GLLDGLCATTHWKYAARL-------------------QRERVKVDG-----DRIFTRE-GIWTSAGVTTGIDMALAMIE---------- +------------------------QVGLLDLTGAQTVFWAATYERLTGTLS---PVTAEGLT----------------------VET-QPLSGFA---IDTLIVPGSP----D--ESGELIQWIADHSL-ARRIASVCSGTFLLAEA-------GLLEGKRAATHWAMCDRL-------------------GARSIEVDN-----DAIFVQQ-SVWTSAGVSAGIDLALALVE---------- +------------------------GFVLLDATGPAQVFATANYRIRLTA-G---LVSSAGVG----------------------VMTAP-LPRAAL--GATLIVAGGRGLG-A--PDPAIVRWVQR-AGMLRRCCAVCTGAFVLARA-------GLLRGRSVVTHWMDAAAL-------------------QAQELRVLD-----DAIYVKD-AYYTSAGIAAGMDLALSLVE---------- +------------------------GANPLDIAGPSSAFDMANYDICHAS-G--E-CTESGLR----------------------LASLSPLGGIE---IDTLMIAGGD----R---DQQFLDEVRRLAG-ARRAGSVCTGAFLLGAA-------GLLENRRAVTHWASCDRL-------------------GAMGVTVCP-----DAVFVRD-KIFTSAGMSASLDLSLGLIE---------- +------------------------NCVLLDLVGPLQVFTHA-YQTHVAS-S--M-ITNTVLD----------------------IDSSP-LEEWR---IHTLIIVGGD----K---DVPFVRQIKALAQ-AQRICSVCSGAILLAAA-------GLLDNRRAVTHWEDCDQL-------------------AKGDVRVEV-----DPIYIRD-AVWTSAGITAGIDMALAIIE---------- +------------------------GVSSVDASGPLEPFGLANYKPVTVS-D---PVVAGGFN----------------------IVPSC-ACEDAR--IDLMLVAGGP----A--EDETLLSWLRR-LR-CARLGSVCTGSTILVAS-------GIADGHRVATHWLEAIRL-------------------KQCAVEIEE-----DAIFVNS-KLWTSAGMLAGIDLTLALIE---------- +------------------------GAEAVDIAAPASVFTKAEYRLCFAS-K---DVTNSGLW----------------------IRATHSFEAVP---LDTLIVAGGD----L--RDGSVAEWLARVAG-TRRIASVCSGAFALAAA-------GLLDGREATTHWSALDLL-------------------QSVAVRVLR-----DRIYVRD-QVWTSAGVTTSLELALALVE---------- +------------------------GVEAIDIAAPASAFSKATYRVHMAS-R---AVTSAGFA----------------------VADTVPMQAMG---IDTLIVAGGE----I--YEDGAGAWLAQAAR-SRRVASVCTGAFALAAA-------GLLEGCKATTHINACDLL-------------------AQLGTQVQR-----DRIFVRD-ALWTSAGVTTGLDMALALIE---------- +------------------------GYQPLDLVGPMQVFALANYVLTTIT-R--R-VASAGPD----------------------ILVDEGLERL----ADTVIVPGGP----A---DIAITDAISLSQT-VRRLCSVCTGAFLLAAA-------GVLDGRRATTHWGRCDAL-------------------QAARIAVEM-----TPIFVND-NVWTSAGVTAGIDLALALIE---------- +------------------------GIHMLDLAGPLQILSTVALAVRCVGPH-SSVQAFQGIE----------------------LGRVGPLPAR-LLPGDLVLAIGSKMTD-RSPAWRDTADWLRGVAADRPTIAAVCTGAYLLGEA-------GLLDGRLCTTHYAHVGRL-------------------RAKGATVVD-----NRIFVSDGNIWTSAGVASGIDMALQLVA---------- +------------------------GAMGSSVAITLDVLRTANITWKIIG-SSE-SVMRNGMR----------------------LDA-QPLDKVQAI-GSMLVIPGLGLEN-GHADIRKLSQLVHDHHRRGQQTAASCSAVFVLGEA-------GVLEGHTVTTHWQLYETF-------------------KEREAILDT-----KRMLIHDGNMITAGAGMSQMDLMLYILR---------- +------------------------GFELFDVAAAIRVFEAANYDIHIFAPAAT-PVGAGSTI----------------------LNM-SALPTDFGE-VHTAMVIGGTASH-SSTHTSHARDWILQHRSKIDRIASVGTVGFTVADA-------AH---------------R-------------------RAGDAR----------------RLWDAVAASAGMKLALKLVA---------- +------------------------GFQLVDLG-AMTVFDLANYDLRIVSAH---PVSAAGAT----------------------LQT-QAW--RDA--FDTVLVFGAA--------DADTVALLRRAAG-ARRVGTVCNGTALLAPT-------GLLDGRLVAVRAMHAAGL-------------------QARAIRVDP-----DRVWIRD-KIWSSAGMTASIDLALALVE---------- +------------------------GRMLMDFVGPADVFTTANYDVRIAS-T--KKVTGAGAD----------------------ILCQV-SAIDSR--IDTLIISNYD----E--LFEPFYRWLSKRTN-TRRIASVCAGAFALAQA-------GLINNHKVTTHWGLNEKL-------------------QKTQLSVDT-----NPFFVKD-HIYTSGGVSSGIDLALAMVE---------- +------------------------QVQLLDFAGPSDVFNTANYQIHLISGTVDKSVTSAGIS----------------------VQCDYTIYDQHIP-LDTLLIAGSK--A-THEYDRAVLHWIKGIQPTVKRIGSICIGAFLLAKT-------GLLTNKKVTTHWQYAKVL-------------------QETSIRLTY-----DHFYIKDDNIYTSGGITSGIDLALALIE---------- +------------------------TMWAFDVISIIQIFDDDS--IDFI-ANAS-SKLDHGMS----------------------IAT--TALRDYHE-PDLIIIPGFANPH-DPADALAIRDWLVASHREGVEIAAMCTGMFALAWT-------GLLDGVECTTHLPFLDDL-------------------AAQKALVQK-----DRLLTHNARIWTSAGGSICLDLCIALLA---------- +------------------------YYKLLSIAAILEVFETANFEIMVFQSAEQ-I-EKILFG----------------------YEV-NSIEDS-DK-LDLILIPAFTTD-----KNKNFIPWLQKQHQAGAELASFCTGAFLFAAS-------GLLNEKLATTHVDACSAF-------------------TKALVKLKS-----EETLTADGSLYTSGGSTSSFHLLILLVQ---------- +------------------------NHRLLSLAAIVDVFDTVNFDLHLIGINEG-L-QTPFKH----------------------LPY-STFEQS-EI-EGIIIVPAFRDH-----KNAVFIPWLIKAYQNGIRVASCCTGTFLLAAA-------GILNGKKATTHVEACDAL-------------------QSIEVELLP-----HAIFTVEHHLYTSGGATSTFHMLIFLIQ---------- +-------------------------MWCYDFSTVLQVFDGDI---SIL-SPFE-HVLNHNVV----------------------VTP--EALGD-PE-YDLVITPGFFHPT-QPA-CEMARQWLIRAHAAGADVASLGTGTFFLGWA-------GLIDGVEVTTHWMFSDIL-------------------QRRHAIVRP-----ESLFVHDERIWTCGGGTSSLDLCLTIMR---------- +-------------------------MRGFDLCAALEVFGGDRNDVAAVSPSP---EELEGGL----------------------RIRA--LPLQEAD-SDLLVIPGFADPL--GAVDPDVVRAVLRLHSSGTHIASLCTGAFLLAAT-------GLLDGADATTHWRFCDEL-------------------QRRRVRVDP-----KVLYTHDARLWTSAGVAAGIDACLAILA---------- +---------------------------ETEIQAFSQFFPKHGYEIVYISRLWNNPV-----------------LEFTGNEHLDPLRVRCDVDQVNPSDFKGFILVGGYA-MDRLRYNPQALNLIRKISQKGLKLGTICHSLWLLTPD------KTLLRGKKVTCAHNIID-------------------DVKNSGAEYQNSG--GTVNTYVDGDLITAKHPGVVEEFMKVYL----------- +--------------------------------------------------------------------------------------------------------------------------------------AAICISPVVLAQA-------RLLKDRKATVWNGDGKQE----------------EILTAQGAEYVD------QDVVVDSRIVTANGPPAAKKFGKTIAEM--------- +MRPQEVHLFVFDN---L--SDWEASYAIAGINNPQFQKKSGIYRIRSVAITRAPVVSTIRIQPD------------------------LALDELSQRDSAMLILPGGIA--WDEGKNREAIEVARVFLDSRVPVAAICGATAGLAHG------------------------------------------------------------------------------------------------ +--MFTIYVYVLDT---L--ADWELGHVISELNSERFFKGAQHVSLKMVSYSREPIHTMLTIVPD------------------------CLINDIVVSKTSMLLLPGADT--WNDPKHVAVIEKASEFLTLGAAVCAICGATAALANF------------------------------------------------------------------------------------------------ +-MKKIIYLYILES---M--AEWEVGYILQAISMESMLKQNREFVIKTVSTSKNPIKTILTITSD------------------------CLLDEMDEDNMVALLLPGAES--WNSEENNQILEKALSYIDRGILVGAICGATLALADL------------------------------------------------------------------------------------------------ +--MKTAYLLVFDG---L--SDWEPGLAIAEINK------SKKYQVKTIGLNQNTVTTVVSIVPD------------------------YTLDEINYGDAALFLLPGGEL--LEKSPLPPLVPVVRRFRKLEIPVAAICGPTVFLAPP------------------------------------------------------------------------------------------------ +-MKQKVLFVLLNG---Y--ADWGAFLST--ALHVAVIPGEIKYEVHTVAPTLDTVRPIFRTLPD------------------------YSFENMPKD-YAALVLIGGNR--WDSPEAELVAPLVKEALDKDKIVGAICNGASFLCSH------------------------------------------------------------------------------------------------ +--GKKIAILVNSQ--YI----------AQEIKGYQEKFTAYGAKVDLMSRLWGQTE------QTFVSE-----VEQEG-KTPETLTVWIDFTQVNLNDYAAVIMAANYPSVSSGRLSPA-VQFIYQAMMNPKIKGFPCHALWLLTPIP------EVLAGRKVTCNRVMLG-------------------DVSNAGAIISET----ASGVVVDSDIVTSDSDSHREAFIEAICQQ--------- +--NKKVAILVESQ--YI----------PEELRAYREKFEAYGATCHFVSRLWGQSS------QTFISE-----LEDPQ-GTPETFRVDIDVESVRPEDYAAVIMAANYTSVHTMRDTPA-VKFFADAMRNPRVKGALCHGLWILTPTP------ELLTGRKVICHEVVAS-------------------DIVNAGAVITPS----TSGIVVDRDLVTGHSKNEAGAMVDAIKEL--------- +--GKKIAVIVESQ--YI----------PAEIRIYRERFAGYGATVEFVSRLWGQPS------QRFYST-----VEPGVTDEIEWLEVDKDFGSVSPDEYAAVIVSANYTSVEVARNVPA-AHFFRRAMQNPAIKAAACHGLWLLTPSP------DLLAGRKVICNKVVLA-------------------DVVNAGGIYTPC----APGVVVDRDLVTNNSWHATEALVDAVKDL--------- +--GKKIAVLVESE--YI----------PEEIRVYQERFASYGATVELLSRLWNQPQ------QQFFSD-----QEDPD-KTPETLVVTGDIEKARPQDYAAVIMAANYTSVDMVRDAPA-VGFFARAMRNPDVKGAPCHALWLLTPCP------ELLAGRRVTCNPVVLA-------------------DVVNAGAVYVPA----PAGVVVDGDLVTNPSYRSSALLVDAIREA--------- +--MKKFLGIITNVSKYP-SAEKPTSLWLGEAVYFAHEVEKAGYAVDYASHKGTYT-------------------------------------PIDPNDY-----AGGHGAVWDFPDNAALTQV------------------------------------------------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------------------APQPDVIVVPAQR-----S--TEESRAWLKAASAKAEVTMSVCTGAFQLARV-------GLLDGLPATTHHDFWDAF-------------------EKEKVRLQR-----GPRFVDNGRVATAGGLTSGIDLA--------------- +-----------------------------------------------------------------------------------------------CPQPGILLIPGGVVEAELA--KPQVVDWVAHASKSAAVTASVCTGAFILAKA-------GLLAGRTATTHWEDLADL-------------------RLADVQVIA-----GKRWVDEGAVVSSAGIAAGIDMS--------------- +-------------------------------------------------------------------------------------------------RADIVVVPGALG---SLPLGTPLSSLLEALARPEVLVATVCGGSLLLAMA-------GLIKGRNATTHHLGLEAL-------------------GAN---TVV-----DARVVDDGDLVTASSVTSGIDLG--------------- +-------------------------------------------------------------------------------------------------RADLVVVPGATG---PAELDTGLPALLESLARPGVTTAAVCGGSVLLALA-------GLITGRPATTHHLGLDTL-------------------ARA---TPV-----RARVVDDGDLVTAAGVTSGLDLG--------------- +------------------------------------------------------------------------------------------------EAADIVVIPWWGT---TAHL----LDALNCARQNGAQIVGLCLGAFVLGYA-------GLLDGKRAATHWEFEQDF-------------------QARAARLDI-----NALYVDDDGIITSAGTAAALDCC--------------- +------------------------------------------------------------------------------------------------DNADIVIVPSWPN---TLPL----LTKLRAAHQKGATIVGLCLGAYALAKA-------GLLDGKRATTHWGFQDAF-------------------QAENVIVDC-----DPLFIDEHQIITSAGTAASLDCC--------------- +------------------------------------------------------------------------------------------------EIADIIIVPTWND---FDEL----QMALQQANARGATLVGLCLGTYALAYS-------GLLDGKRAATHWMGEADF-------------------HQRQVRLDL-----NALYVQQGNLMTSAGTAAGLDCC--------------- +------------------------------------------------------------------------------------------------EQADIVVVPYWGEVNQRPPL----IASLIRARDNGAEIVVMGIDTVALEGK-------GFKR------LVEEGAQV-------------------KAGILEMD-------LAFLNAN------------------------------ +------------------------------------------------------------------------------------------------AWADIVFVPGYRF---PDRV----VDALIAAHDRGARLAAISTGAFALAAT-------GLLDGRRATTHWHYTRAL-------------------VARLVQVDE-----NVLFVDEGSVLTSAGAASGIDLC--------------- +------------------------------------------------------------------------------------------------ASADLVIALPWAD---FRTV----LDALSAAHARGSLVAAHCVGAFALAAA-------GLLDGRRATTHWRFARLL-------------------ADREVTVEP-----DALYIDEGRVITGAGAAAGFDLC--------------- +------------------------------------------------------------------------------------------------AACDLVVVPGVER---PDEV----HAALRAAHGRGVTIASLCAGAFVLAEA-------GLLDGRTATTHWALADRL-------------------AERAVDVRP-----EVLFTGEGRLWTSAGVAAGIDLC--------------- +------------------------------------------------------------------------------------------------AVPDTAIAVGARDIERALRL----VGWCRDVSARIGRMVGLCSGCFFLAEA-------GMLDGRRATTHWSVAPLL-------------------RARAVKVEP-----DAIFVREGNVWTSAGVTAGLDLA--------------- +-------------------------------------------------------------------------------------------------LADTWMITGTLTP--LTPV----LASVRGFVDGARRTAGLCTGCFVLAQA-------GVLDNRRATTHWAYAKKL-------------------RELKIEVEE-----DRIFIVDGQIWTSAGMTAALDMA--------------- +-----------------------------------------------------------------------------------------------DEPINTLIVPGSAFISQALRL----VDWLRVTSATANRTTSVCSGAFFLAQA-------GLLDGLRVATHWLMADMF-------------------ERLRVELDR-----EAIFVHQASVWTCAGVSAGIDLA--------------- +------------------------------------------------------------------------------------------------ETADTLIVPNRPDVEVPRRV----LDAIARAHARGARLIGFCSGAFTLAEA-------GVLDGRRATAHWQWADSF-------------------RSRAVRLES-----DVLFVDDGDILTAAGSAAALDLG--------------- +------------------------------------------------------------------------------------------------ATADTVVVPASYELGPVHEE----LAAALAHIRPGTRLVSICTGGYVLAAA-------GYLDGRRATTHWASAEHF-------------------QRLAVRVDA-----DVLYTDDGDVLTSAGVAAGIDLC--------------- +------------------------------------------------------------------------------------------------VHADTVIVPACAD---PDAL----VDAVRAAHDAGARVASLCTGAFVLAAA-------GLLDGRRATTHWLHAAAL-------------------AEREVVVDP-----DVLYVDHGTVLTSAGKAAAMDLC--------------- +------------------------------------------------------------------------------------------------ARADVLIVPSWRD---TQEM----VNAVRDAYERGATVVGLCLGAFVLAEA-------GVLDGHEATTHWSAADAF-------------------SQRRVKLVP-----DVLYLDAGRLVTSAGTAAGLDCC--------------- +------------------------------------------------------------------------------------------------GPGDILLIPGGMGSRQLVL-QDDFLAALRKAALASTLVMTVCTGSALAAAA-------GLLDGLHATGNKKAFDWT-------------------MSMKVLWQR-----DARWTRDGKFYTAAGVSAGIDMA--------------- +-----------------------------------------------------------------------------------------------H-QTDILLMVGGMGTRQQIN-HRSFLQTLTILVDHADWVLSVCTGSALLAKA-------GVLDDKRATSNKLSWQWV-------------------IAQKVHWAE-----QARWVVDGKFYTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------QDSDILIVSGGMGTRTLVT-DDWFLSGLGDLASKTKWVLTVCTGSALLAAA-------GILDGRHATTNKNAFDWV-------------------RNQSILWER-----EPRWVRDGNIYTAAGVSAGTDMA--------------- +-----------------------------------------------------------------------------------------------N-PTDILLIVGGFGTRQLIE-DSQFLDTLANLANDAKWVLSVCTGSALLAKA-------GLLDNRQATSNKIAWEWA-------------------TSQKVNWIK-----KARWVVDGKYYTSAGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------EKTALMLVPGGQGTRRLVS-DEGMLTALRTAAQHAQWCLSVCTGSALLAAA-------GVLDGRQATSNKRAWQWA-------------------TSLQVNWVK-----KARWCADGRFYTSSGVSAGTDMA--------------- +------------------------------------------------------------------------------------------------EKTALMLVPGGQGTRRLVS-DEGMLATLRTAAQHAQWCLSVCTGSALLAAA-------GVLDGRQATSNKRAWQWV-------------------TSLQVNWVK-----KARWCADGRFYTSSGVSAGTDMA--------------- +------------------------------------------------------------------------------------------------DGGGILVVPGGRGTRRLAV-FPPFLHFLRGMADDAEYCLSVCTGAALLAGC-------GALDGRRATSNKKSFAWV-------------------KSVAVGWEE-----RARWVADGKFYTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------KPNGIFMIPGGQGTRGLIH-DDTFMKQIKEIAEQSNFCITVCTGSALLAKT-------GLLKNRRATSNKLAFDWV-------------------KSIEVNWIP-----NARWVVDGKFYTSSGVSAGMDMS--------------- +-----------------------------------------------------------------------------------------------EEIDGILIIPGGKGARRLLWE--RALNIIKKAAENSDYCLMIGNGSAILAQT-------GLLYRRRIADFPMDTNWN-------------------RMFGIERIE-----GAKVAIDGKFYSCGNTILGMDTA--------------- +------------------------------------------------------------------------------------------------EPMDIALLPGGKSTLSLQH-NPVFLHHLTRLANAAEWMLTVCTGSVLLAQT-------GLLDGRQATSNKSAWQAV-------------------IDSKVNWQH-----KARWCVDGKYYTSSGVSAGMDMS--------------- +------------------------------------------------------------------------------------------------AKFDILLVPGGFAARELAH-EGEFIAILGELAHRHDRVITVCTGSVLLAKT-------GLLDGMEATSNKLSWQWV-------------------TSESVRWIR-----AARWCVSGKFYTSSGVSAGIDAA--------------- +------------------------------------------------------------------------------------------------NIEKILLVPGGIGTREKVD-DNNFINFIENISNQSKYIISICTGSALLAKT-------GILNGKKATTNKLAFKWV-------------------TEQDVLWVK-----ESRWVKDGSIYTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------HAAGVFLLPGGPGTRKLVN-EPLFLDKIKEIAEQATSVLTVCTGSALLAKT-------GLLDHKQATSNKRAFKWA-------------------TAQQVLWIK-----KARWVKDGNLYSSSGVSAGIDMV--------------- +------------------------------------------------------------------------------------------------KYKEIVFIPGGAGTRKGVE-DYDLLKYIKDISLYSKYILTVCTGSALLAKS-------GLLDGREATSNKRSFNWV-------------------KEQKVLWIK-----EARWVKDGNIYTSSGVSAGIDMS--------------- +------------------------------------------------------------------------------------------------DILKILFVPGGSGTREKVN-DDDFINFIENMSKESEYIISVCTGSALIAKA-------GILNGRRATSNKRAFKWV-------------------TEQDVLWVK-----EARWIKDGNIYTSSGVSAGIDMA--------------- +-----------------------------------------------------------------------------------------------QSEIDTLFIPGGTGARTLIL-EADYINQLKQLAQKSRYVLTVCTGSALLAKS-------GLLDGKRATSNKLSFEWV-------------------KTSRTQWIE-----KARWVTDGKYYTSSGISAGMDMA--------------- +------------------------------------------------------------------------------------------------NSTGILLIPGGQGTRRLVD-DSIFIDTLSSFAKKAEFCLGICTGSVLLAKT-------GLLNNREATSNKKAFDWA-------------------VQMDVCWKR-----KARWVVDGKFYTSSGVSAGIDMA--------------- +------------------------------------------------------------------------------------------------DESGILVIPGGMGTRELVN-NTCFLDKLKLIAEKSTYCLSICTGSAVLAKC-------GVLKNRKATSNKQALEWV-------------------KSVQVNWIE-----KARWVADGKYYTSSGISAGIDMT--------------- +------------------------------------------------------------------------------------------------DESGILVIPGGMGTRELIN-NTLFLNKLKSIAEKSTYCLSICTGSAVLARC-------GVLKNKKATSNKQALKWV-------------------KSVQVNWVK-----KARWVADGKYYTSSGISAGIDMT--------------- +------------------------------------------------------------------------------------------------PYNSVLFIPGGMGTRLLVD-DTVFICWLDKMIAQALYCLTVCTGSALLAKT-------KRLNGKYVTSNKNAWSWV-------------------TSLQVNWQE-----KARWCVDGHLYTSSGVSAGIDMA--------------- +-----------------------------------------------------------------------------------------------S-TRYVLLIPGGTGARDLVN-DETFISSLGSLAEHAEFILTVCTGSILLSRT-------GILNGRRATSNKRVFAWT-------------------KT-GVTWEE-----KARWVRDGTIYTSSGVSAGMDMA--------------- +-----------------------------------------------------------------------------------------------PEETDILLIPGGTGTRKEID-NPVFIEKISTLAGSSQYTLTVCTGSALLAKT-------GLLDGRSATSNKRAFGWV-------------------ESAKVNWIK-----QARWVKDGKYYTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------SKEYVLFVPGGIATRQLIN-DKNLITKLTKLAIDAKYIFTVCTGSSLFSKT-------NLLNGKKATSNKKALNWT-------------------KSIDVIWVD-----KAKWVKDGNIYTSSGVSAGIDMS--------------- +-----------------------------------------------------------------------------------------------HQQLHWLLVPGGIGTRREAA-NPALLEYIRAWAAPSQLCMSVCTGAALLAAA-------GALDGRRATSNKRAFDWV-------------------KSVRVDWVR-----SARWVRDGNFVTSSGVSAGADMA--------------- +------------------------------------------------------------------------------------------------SETGILLVPGGIGTRLLVH-DHGFLTQLGEAAQRADYCLTVCTGSALLAKT-------GLLDGRRATSNKRAMDWV-------------------VSVAVDWVH-----RARWVVDGKFYTSSGVSAGIDMA--------------- +-----------------------------------------------------------------------------------------------HAEGDILLIPGGAGTRTLVQ-NQVFLAELAKLCQSHRFVLSVCTGSALLAAS-------GVLNGKTATTNLNAFDWG-------------------QSLQVRFVR-----Q-RVCQDGQFFTSAGVSAGIEMA--------------- +-----------------------------------------------------------------------------------------------HAEGDILLIPGGAGTRTLVQ-NQVFLAELAKLCQSHRFVLSVCTGSALLAAS-------GVLNGKTATTNLNAFDWG-------------------QSL-----P-----QVRFVRQRCQDGQFFTSAGIEMA--------------- +-----------------------------------------------------------------------------------------------EMENGILLIPGGRGARRVIHR--ETIELLQKLVSNADTCLMVADGSGFLAQT-------GVLYRRNIAEYKMNENWK-------------------RMFAVYWIP-----NVSWVADGKFYSSSSSLYGIDMA--------------- +-----------------------------------------------------------------------------------------------VEIEDIFLIPGGTGVKSFLHE--NGQQLLKQAVEEASFCMMVQNASALLART-------GLLFHRQVADYAYDENWK-------------------RMFGIDYID-----GEKWISDGKYYSCSTTVAAMDMT--------------- +-----------------------------------------------------------------------------------------------VEIEDVFLIPGGKGVKSFLHD--KGQQMLKQAVEEASFCVMVQNASAMLART-------GLLFHRQVADYAYDENWK-------------------RMFGINYIS-----RENWISDGKYYSSSTTMAAMDMA--------------- +------------------------------------------------------------------------------------------------EIGNAILIPGGSGARRLLE-DFDSLEILKEAIEKSSYCLTISTGSALLAKT-------GKAFRRRMAQYEKNIFWA-------------------LHTGVHWIE-----GAKWAADGKYYSSSGSMAGMDMT--------------- +------------------------------------------------------------------------------------------------PPGSILLIPGGIGTRSLVM-NNLFLQNLAKLVQQSQTCLTVCTGAALLAAT-------GVLDGKPATTNKRAFEWV-------------------RGTQVGWRQ-----KARWVSTEKFYTSSGVSAGMDMT--------------- +------------------------------------------------------------------------------------------------KPGSVLLIPGGAGTRTLVH-DTDFAEALTRWVQQSEYCLSVCTGSALLAAT-------GLLNELEATTNKRAFDWV-------------------RGTHVLWQG-----TARWTHSGKFYTSSGVSAGMDMT--------------- +------------------------------------------------------------------------------------------------EPNSVLLIPGGFATRTLVK-DQAFLDKLLILSKSAKYVLTVCTGSALVGMT-------GQLDGKEATSNKRALDWV-------------------RETKVKWKK-----KARWVKDGKFYTASGISAGMDMA--------------- +------------------------------------------------------------------------------------------------QDGVTMLIPGGPGTRVLVK-DQEFLRTLRQQLPRFSQLLTVCTGSAVLAAT-------GAIDGRRATSNKRSFTWV-------------------TSVEVHWIG-----HARWVIDGDLVSSSGVSAGIDMA--------------- +-----------------------------------------------------------------------------------------------THTESILLIPGGIITFELMK-NQEFLDQLKALADQSRYVLTVCTGSSLLAAT-------GILNGVKATSNKMALEIV-------------------QSLQVLWQT-----QARWVTDRKFYTSSGVSAGMDMT--------------- +------------------------------------------------------------------------------------------------DPSGILVVPGGLGTRKLVL-DMQWLAHLKELSVQAAYVLTICTGSALLAKT-------GLIDGKQATSNKRAFDWV-------------------MSTAVKWQR-----KARWVVADKYYTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------EDGGILLIPGGWGSCDQVD-NKAFLEAIQAAAEKSEFVLTVCTGAALLAKT-------GMLDGKTATTNKRAFDWV-------------------KSCEVEWNR-----MARWVHTDNIYTSAGVSAGIDMA--------------- +------------------------------------------------------------------------------------------------NTSGALVIPGGAGTRTLVK-EEPFLKNLRRLSEEAAFVLSVCTGSALLARC-------GILEGKRATSNKRAFDWV-------------------VSTKVHWIR-----KARWVHDGKFYTSSGISAGMDMT--------------- +-----------------------------------------------------------------------------------------------LVEPDIVLVPGGGGTRRLVD-DVRFLGRLAEIGRRARLVVSVCTGSALLAAA-------GLLDGRRATSNKRSFAWA-------------------SGFSVTWEP-----RARWVHDGDRWTSSGVAAGMDMT--------------- +------------------------------------------------------------------------------------------------PGGEALLIPGGQGTRTRVD-DEEYLHWLYGLANASNVCMTVCTGSALLAKT-------GLLDGVRATTNKRAYNWV-------------------TSLQVRWQP-----RARWVHDGKFWTSSGVSAGMDMA--------------- +------------------------------------------------------------------------------------------------PEKSILLIPGGQGTRQLVK-DMPFLTWLTQLVDEAEFCLSVCTGSALLAAM-------KQLDGKWATSNKLAFEWV-------------------RQIDVKWKA-----VARWVRDGKFYSSSGVTAGMDMT--------------- +------------------------------------------------------------------------------------------------PAGSVLLVPGGMGTRTLVS-DNTFLQMLAARVREAKWCLSVCTGSALLAAA-------GCLDERSATSNKKAFGWA-------------------SSFGVDWKK-----SARWVADGKFYTSSGVAAGMDMA--------------- +------------------------------------------------------------------------------------------------PPNSLLLLPGGQGVRKMVE-DKIFLSSLEKAVQQAELVLSICTGAALLAQI-------GQLKGRKATSNKLALSWV-------------------ASHEVLWQD-----QARWVVDGKFYTSSGVSAGMDMS--------------- +------------------------------------------------------------------------------------------------IPCQLFMTVGGLGTRTEVN-NPKVINWIKSQTAVSEKVFSVCTGSALLAKA-------GVLDGVSATTNKLAYQWV-------------------TSLQVLWQA-----KARWVNDARFLTSSGVSAGIDAS--------------- +------------------------------------------------------------------------------------------------DPVRILLVPGAAPQ-VLPK-EKAFFEAGKAAAQKAEYVLTVCTGSFLVAQT-------GLLKGRKATSNKKALPMV-------------------MKRDVNWQK-----KARRVADGKFYTSSGITAGMDMV--------------- +-------------------------------------------------------------------------------------------------APEILLIPGAAPQ-WLKL-EPAFFDAIRRAAEKAQYVLTVCTGSFLLART-------GFLNGRKATSSKNAIPMV-------------------LENKVLWQK-----KARWVEDGNVWTSSGITAGMDMA--------------- +-----------------------------------------------------------------------------------------------CPPLDVLVISGGIGTRILMH-NTRVVDWLRSQIHDVRHVLSVCTGAALLAAT-------GLLDGKPATTNKELFTYI-------------------RQLAVQWQG-----TARWISQGKVVTASGVTAGMDAA--------------- +-----------------------------------------------------------------------------------------------HPPLDLLMIPGGVVDAPLA--DARTLAWVADQATQVETVASVCTGVFVLAAA-------GVLPGCSCTTHWEDIDDL-------------------QRATLKIHS-----SMRWVNAQPLYTSAGISAGIDLA--------------- +------------------------------------------------------------------------------------------------PKESVLLLPGGQGTRTLVN-DSEFISKLKECVLASQICLSVCTGSALIART-------GELDGLKATSNKRSLEWV-------------------KSCAVKWQE-----RARWVRAGKFYTASGVAAGMDMA--------------- +------------------------------------------------------------------------------------------------PENSILLVPGGQGTRPLVQ-DMVFLRDLGVWLDQAACCLSVCTGAALLAAS-------GRLDGLPATSNKQAFDWV-------------------RSVLVDWQP-----AARWVAAGRLYTSSGVSAGMDMT--------------- +-----------------------------------------------------------------------------------------------E-KLDIFLIPGGQGTRKEVN-HTTLIEKIQMLSASSVYTLTVCTGSALLAKS-------GQLDGITATSNKRAYDWA-------------------TSQKVKWIK-----KARWTVDGKFYTSAGISAGMDMA--------------- +-----------------------------------------------------------------------------------------------N-NPEIILVPGGMGTRKEIN-NSRLLHKIKELAQESEYVLSVCTGSALLAKT-------GLLDGKEATSNKRAFSWV-------------------SSQKVDWDK-----KARWKIDGKYYTSSGVSAGMDMA--------------- +-----------------------------------------------------------------------------------------------PGPLDVLLVPGGQGTRREVD-NAALLESLRRLAETTPLVASVCTGSALLARA-------GLLDGHRATSNKRAFPWA-------------------VSQGVHWVP-----EARWVEDGKFFTSSGVAAGIDLA--------------- +------------------------------------------------------------------------------------------------QQKDILLIPGGKGTRQLVD-NENFIKKLKTLAEESKYVLCVCTGSGLLSKT-------GLLDGRKATSNKKAWEWV-------------------TAQNVHWIK-----KARWVVDGKYYTSSGITAGIDMC--------------- +-----------------------------------------------------------------------------------------------SQKWDLLLVPGGQGTRALVG-DEPFLATLALLCDASAAVASVCTGSALLAAA-------GVLDGRKATTNKRGWAWV-------------------TESTVEWTP-----RARWVADRCATS-SGVAAGLDMA--------------- +-----------------------------------------------------------------------------------------------AAPADIVLVPGGRGTRRLVA-DGRFLSWLRGWAGSASLVTSVCTGSALLAAA-------GLLDGYDATSNKRAFDWV-------------------RTHDVRWIR-----RARWVEDRDRWTSSGVAAGMDMA--------------- +-----------------------------------------------------------------------------------------------APVADIVLVPGGRGTRELVD-DHDFLAWLRTWASAATLVSSVCTGSALLGAA-------GLLDGYRATSNKRALAWV-------------------MEQQVRWEA-----QARWVEDRDRWTSSGIAAGLDMT--------------- +-----------------------------------------------------------------------------------------------AAPTDIVLVPGGPGTRRLVR-DQQFLQMLTHLAAPAAIIVSVCTGSAVLAAA-------GLLNGYRATSNKRAFDWA-------------------SGHGVTWVR-----RARWVHDRNRWTSSGVAAGMDMT--------------- +------------------------------------------------------------------------------------------------FSGDTLLVPGGRGTRSLVQ-DPEFLRQLTALASSADIIASVCTGSALLAAA-------GLLENHTATTNKNAFDWV-------------------RTHKIEWKK-----QARWVHDGNLWTSSGVAAGIDMA--------------- +-----------------------------------------------------------------------------------------------CGDIDILLVPGGPGTRALVD-DESFISWLSATGAKAQLVTSVCTGSALLARA-------GLLEGYRATGNKVAFEWA-------------------RTFTVAWQP-----EARWVEDRDRWTSSGVAAGMDMT--------------- +-----------------------------------------------------------------------------------------------AAASDILLLPGGAGTRPLVS-DEKFLDILREHASRAGIVASVCTGSLVLAAA-------GLLDGYRATSNKSLFSFV-------------------SQHNVTWEP-----RARWVEDRDRWTSSGVAAGMDMT--------------- +-----------------------------------------------------------------------------------------------QEPLDLLMVPGGRGVNSLLEGLAALLDWLRSADGRVPVIASVCTGAALLAKA-------GLLDGMPAATNHQAFGWV-------------------AGFNVLWDN-----TSRWVDAGKRVTSAGVSAGTDMA--------------- +-----------------------------------------------------------------------------------------------APDFDILLVPGPNPYGFELD--PRFKELIHRQV-SGRLLFTNCTGACIAAQA-------GVLDGKKATVNHAFLKWA-------------------AKENVNWTA-----EAQWVVDGNVWTAAGAVAGMDMA--------------- +-----------------------------------------------------------------------------------------------CPKLDYLLIGGPSPD-YTKNIPPAIASFVRERV-EVKIVFTTCTGGLFASML-------GLLDGLKATTNHEAIAIA-------------------REFNVKWTA-----EKNWIVDGKFWTAGGACAGMDMM--------------- +-----------------------------------------------------------------------------------------------CPKLDAILLGGPGPD-FWNNIPDSYREFLHRKV-EVDYFFTTCTGGIVAAKA-------GLLRGKRATTNWEFLDYV-------------------KKDETTWET------ARWVIDGKFWTGGPAFAGIDMF--------------- +-----------------------------------------------------------------------------------------------CPKLDAILLGGPGPE-FWNNIPDSYREFLHRKV-EVQYFFTTCTGGIVAAKA-------GLLRGKRATTNSEFLDYI-------------------KKEDTTWET------ARWVIDGKFWTAGGAFAGIDMF--------------- +-----------------------------------------------------------------------------------------------CPKLDYLLIGGPHPE-FFLNVPDVFANFIRERV-GLQGLFTTCTGGMVAATV-------GILDGRTATMNHQYLAKA-------------------KELDVNWSS------KQWVVDGKFWTAGGAVAGMDMF--------------- +-----------------------------------------------------------------------------------------------CPELDYLLVGGPSLE-YAENLPKDMRNFIAEQS-TVKSLFTTCTGGLVVAAT-------GVLDGVSATANHTVLDHG-------------------REVRVKWNG-----QKNWVVDGKFWTAAGAVAGMDMM--------------- +-----------------------------------------------------------------------------------------------CPKLDYLLVGGPDPA-WTQDSFPAYAKFVQERL-ELKIVFATCTGAIILGAM-------GVLDGLNATVNHQLIGPA-------------------RQMKVKWTD-----EKQWIVDGKFWTAGGAVAGMDMM--------------- +-----------------------------------------------------------------------------------------------CPPLDYLLIGGPSPG-YRLS--ECYESFIRRRS-EVKAIFTTCTGALLLAQT-------GLLDGRDATVNHVLLPQA-------------------RLLKVHWNE-----SQQWVTDGCFWTASGACAGMDMF--------------- +-----------------------------------------------------------------------------------------------CPKLDYLLIGGPETS-YIQNLPSEVSRFLQERV-EVTTIFTTCTGAMVLAAA-------GVLDGIEATTNHGAVPLA-------------------QQLKVKWTR-----EKQWVVGGKFWTAGGACAGMDMF--------------- +-----------------------------------------------------------------------------------------------APDLDYLLIGGPDPATYTL--SERFAEYVKEHV-KGKGVFTTCTGGLIIAPT-------GVLDGVKATTNHVCLEMA-------------------RALQVEWV------GEQWVVDGQFWTAGGACAGMDMF--------------- +-----------------------------------------------------------------------------------------------CPDLDYLLVGGPDTLTFKL--SEAFANFLRKHV-AGRGLFTTCTGALAISPS-------GVLDGKIATTNHGVMNRA-------------------RRLDVKWTV-----EKRFITDGNVWTAGGACAGMDMM--------------- +-----------------------------------------------------------------------------------------------APEIDILLLGGPNPATFELH--PKYAEYIRQHV-AGKVLFTNCTGAFVAATA-------GVLDGREATANHAELGWI-------------------KKRKVRWTD-----ETKWVVDGNIWTAAGAVAGMDMT--------------- +-----------------------------------------------------------------------------------------------CPELDALLIGGPDIAHFELS--PKYADFIRRHV-AGKLIFSTCTGSGVLAST-------GVLDGKAATINNFEYAYT-------------------VRAKVNWTK-----DKKWVVDGNIWTGSGAVAGMDMF--------------- +-----------------------------------------------------------------------------------------------CPPLDFLLVGGPDPS-WVL--AAPLAEMVRDHV-AGKVLYTTCSGAICVAQT-------GVLDGKNATTNHGLVELA-------------------KSLKVKWTK-----DLRWVVDRNIWTAGGAVAGMDML--------------- +-----------------------------------------------------------------------------------------------CPELDILLVPGPYLGNFDLH--PKHADFIRKHV-AGKLLFTSCTGASLVAST-------GVLNGKTATVNNIEFDWV-------------------RNRQVNWTR-----EKKWIIDGNIWTGSGAVAAMDMV--------------- +-----------------------------------------------------------------------------------------------CPELDILLVAGPYLGNFELH--PKHADLIQRHV-AGKILFTNCTGASLVAST-------GVLDGKKATVNNVEYEWV-------------------RKRKVNWTR-----EKKWIIDGNIWTGSGAISGTDMV--------------- +-----------------------------------------------------------------------------------------------CPQIDYLLIGGPLPT-FKLS--EEMSTFIRDRVGEIKTIFTTCTGAAVLAQT-------GLLDGKRATVNMGMIDIA-------------------RQMAVNWAQKT--DKDNWVIDGNIWTANGACTGMDMF--------------- +-----------------------------------------------------------------------------------------------CPPLDYLIIGGPIPS-YRL--PESFKSFIRAHV-AGKGLFITCTGAITVAQT-------GILDGKRATMNHCFFDYA-------------------KKHNVNWTI-----DAQWIVDGKIWTAGGACAGMDMM--------------- +-----------------------------------------------------------------------------------------------LPELDYLVVGGPNPAAFTPD--PAHVDFIRKHV-AGKTLFTTCTGIYVVACT-------GVLDGREATINNQEFYWV-------------------KERNVKWRK-----DKKWVVGKTIWTGSGAVAGIDMI--------------- +-PKPKVLIVMSAADTILLDEKHPTGVFANELMHPVIALENTGIELVFATPGAKRALDPESLKDKYWNKEEKEAFLNSNT----SFLNPISLEVKDQNKFVAILIPGGLSV------------------------------------------------------------------------------------------------------------------------------------- +---------------------AANGAEDVEFTAPVDILRRAGVKVVVASLGDS-------LIVK---TAQ--GL---------RIEGEMPLKDVSEDHYDVIVIPGGLKGAENCRDCPHLTSLLKAQHAAGRWIAAICASPALVLAH------HGLLEDVKAVAYPSFMS------------------------------------------------------------------------- +------------------------GVRLLDVTGPAEVFTTAGYDVRIVSPDGADVTTSSGL----------------------RIGVDAGPPDL-PARLHTLVVPGRSD-WRRAVTNRPLIALVDEPLKRSRRVTSVCAGAFVLAET-------GALDGRRAATHWRLAAQLA------------------TAYRVRVET-----DPVRAGRRRRHVRPGPAATRAV---------------- +------------------------SVTMLDVSGPAEVFSRRGYELVMLSPSGADAATGTGT----------------------GLTITGALPVTRAATLDTVIIPGSDT-LPERPWDPDLLDAAAVLADGPGRVARVRTGAFILAEL-------GLLDGRRATTHWRNARDSGFGSG----------ESLRRAFRH-LQT-----TPSESGI-RPWNPLGTTH-------------------- +------------------------NAQLLDVTGPLQVFTSRPYDAITVATSP-QTGTTSGL----------------------SLATAP-LPDD-DIEIDTLIVAGGRG-VNKACEDVALIDWIRRRSARARRTASVCSGAFLLAEA-------GLLEGKLAVTHWHRCTEFS------------------KRFNVKLEP-----DPIFIQDGEIWTSAGVTAGID----------------- +------------------------------------VLSSAPYDIRVVARGGRSVRTSTGI----------------------SLSTQP-LAPI-DAPADTVIVAGGAG-VDAAARCADTLAWLRAHARQARRVVSICNGAFLLAAC-------GLLDGRRAVTHWQCCDALA------------------RRHRVRVEH-----APIFVQDGPIWTSAGVTAGIDL---------------- +------------------------DAELLDIACVTTTLDSLGYDLVLATPGGRPITCSSGL----------------------VLNGQAALERL-RGPIGTLVVSGGLG-HEGAAHDERLVGHVRRLARESERVASLCTGASVLAAA-------GLLDGKRATTHWHFAKRLA------------------EQYGVEVDP-----RPIWIRDGNVYT-------------------------- +------------------------GFSPFHFSVPCIIFGQDLFCVEICAEKSGVVLSDIGL----------------------SINVEHDLKLL-ET-ADIVIVPYWNH-PEERP-SQALLDALIGAWQRGAEVVGLCLGAYVLAYS-------GLLDQHRAATHWEFEQDFI------------------ERFAVRLDS-----NSLYTSDERLINLSFV---------------------- +------------------------RISAFHLSVPCIVFGDPRYRLLICGENTGSVATGSGF----------------------RIEVTHDLSHL-GE-ADTVIVPAWRD-PDERP-PEALLRSVRAAHARGARLVGLCLGTFVLAEA-------GVLDGRPASTHWAWAEEFQ------------------RSYRVALDQ-----DALYIDDGDILTS------------------------- +------------------------GVLLLDLGIPVQTFGPPHYRVTVCADPSAGPVFADGV----------------------GLATSAGLEAL-RD-ADTVVVPGYED-PEASL-PGTALAALRSAHARGARLVSICTGAFTLAAT-------GLLDGRPATTHWRDAAALQ---------------------------------------------------------------------- +------------------------VQSTFELGIAAEVFGTRYYEFDVCTEKPGPVPTTAGY----------------------AMSVTRGLSAL-AD-ADTVLIPGWSP-VDAPL-SPAVRRALLRAHARGARLVTICSGVFALART-------GLLDGRSATTHWARAAQLQ------------------EEF------------------------------------------------- +------------------------GISPFHLAVPSLVLGSPAYDVVVCAPTPGRLATSAGF----------------------ALHVDHGLEAI-ED-AATVVLPSWHP-DV-EP-PPALLAAVRAAHARGARVVGLCLGAFLVAAS-------GVADGREVATHWRAAERLA------------------QDH------------------------------------------------- +------------------------GSSLMSLAATVEPWRALRADWRLVSLDGGPVLLSSGM----------------------PFAVQGPLGPD-LS-GDLLAIIGGI---DALEHARPALGMLRGLVRRFARVAGIESGAWVLGGL-------GLLEGRRATAHWEDHEEFL------------------LRHGVDVRP-----DR-WVADGPVLTAGGLRGGQRL---------------- +----------------------NRMTELTDYVVPLGVLRRSGAQVLALATEPGPVQMPLRLQPQ------A--------T-------LEEFAQRFPQGADYLIVPAVHD-----SQDPVLLAFIQAQAAQGATIVGVCDGVLVLGNA-------GLLHGRHATGHWYSRKQR------------------LEDYDAHWEE-----NRRYVADGKVITTSGVTAA------------------- +----------------------NRMTELVDFLVPFGLLSRANAEVLALSTGDGPVQMPLKVRAQ------A--------T-------TAEFERRYPQGADYLIVPAVHH-----SDDPLLTAFVARQAAKGATLVGICDGVLVLGHA-------GLLHGRRATGHWYSQARR------------------EADFDTRWQV-----DRRYVADGKLVTSSGVSAA------------------- +----------------------NGMTELVDLLVPFSVLSRAQGEVIALSTQPGPVQMPLRMRAQ------A--------T-------VDAFEQRYPDGADYLIVPAVHH-----SDDPRLTRFVAEQAARGATVVGICDGVLVLGQA-------GLLDGRRATGHWYSRDER------------------QADYRTQWQE-----DRRYLADGNLVTTSGVSAA------------------- +----------------------NRMTELVDYVLPYGLLKRSGAEVVALSTRPGPMQMPLHLLAE------A--------D-------IDGFDRRHPEGADYIVVPAVHH-----SDDPQLLRWVRQQAAKGATVVGICDGALVLGEA-------GLLEGRRATGHWYSRGQR------------------EDDFGTRWVS-----DRRYLADGKVITTAGVSAA------------------- +----------------------NANTELVDFVVPYAVLKRAGADVWALGLEPGPVRFPLRARPD------A--------D-------IAAFDQRYPDGADYVIVPAVHD-----DDDPRLLAWVAGQARKGAVVIGICDGVWVLARA-------GLLEGREAVSHWYSRAAL------------------ADGFGVRWRQ-----DRRYVADGNVVTTTGVSAS------------------- +----------------------ARGTVATDLMAPYAILAESGVDVQVVSATRGPVRTPYAVRPQ------A--------S-------LADLARR---PPDVIIVPALEV-----EDDPARAAWLRDQLARGARIMSICNGARTLAAA-------GLLDGRQATVHWYSRNEM------------------RKRHKVRWRE-----DRRWVTDGPITTTAGISAG------------------- +----------------------PRGTETTDLIAPYAVLAESGIDVRIVAAGMTPIRMPQAVRPQ------A--------T-------YADL--R----PDVIVVPFMMP-----AADPAREAWLKAQAARGARIVSICAGAETLAHA-------GLLDGRDATTHWFELGRL------------------AKAYQVRWRR-----DRRWIVDGNVTTTAGVTAS------------------- +----------------------QRGVETTDLIAPYAVLAESGVDVRVVAPTLAPVRMPQAVRPQ------T--------T-------YAALTRR----PDVVIVPFLMP-----AYDPSRDAWLRAQAQAGARIVSICAGAETLARA-------GLLDGREATTHWYELNRL------------------AKAFKVRWRR-----DQRWIVDGPVTTTAGVTAS------------------- +----------------------PSGVETTDLTAPYAIFSASGVDVKVVSPTMEPAPMPVAVKPQ------E--------T-------QAGFDRRYRQGADMIIVPFLMN-----PKDPARAAWLRTQAGRGARIASICDGALVLAEA-------GLLDGRQATAHWASQGAR------------------ERRFAVVWRR-----DARWVTDGQITTTAGVSAS------------------- +----------------------NSGTELTDFVIPYGVLARSGVQLLSVATKAGPLSRPLTLQAD------A--------T-------TAEFDQRYPQGADYVIVPAVSR-----PTDTPLVAWVAAQGAKGATVVSICDGALVVANA-------GLFKGRRATGHWATESYR------------------KEHYDTQWIS-----NTRYVADGNVISSAGVSAS------------------- +----------------------SVSTEITDFMLPYGVLQRADAQVLAVATEGASITNTLRVQPD------L--------D-------TTAFDQRYPDGADYVIVPAMRR-----AQLAPMLAWLQAQAAKGATVASICDGALVVANS-------GLLKGRRGTAHWATHAYR------------------LEKYDTEWLR-----NVRYVADGKVISSAGISAA------------------- +----------------------SVSTEITDFMLPYGVLQRAGAQVLAVADDGAAITNTLRVQPD------L--------D-------AAGFDQRFPEGADYIIVPAMRR-----VQFAPLLAWLRAQAAKGATVVSICDGALVVANS-------GLLKGRRGTAHWATHDHR------------------VEKYETEWLQ-----NVRYVADGNVISSAGISAA------------------- +----------------------NGGTETTDLIVPYGVLKGADADVAIVSPHAGPVSMPLKIQPD------T--------T-------IHAFDVAHPEGADIIIVPAMHD-----SRNEAVIGWVRDQSGKGAVVVSICEGAWIAARA-------GILDGRAATTHWYAFDKI------------------ARNFRARWVR-----DQRYVFDDNVMTTTGVTAS------------------- +----------------------NKGTETTDFIVPYGVLKASGVDVVTVSTEPGVVEMPLRVVAD------M--------S-------TEGFDSAQPQGADVVIVPAMHD-----DENPAVVTWIRAQASKGALIVSICEGAAVVANT-------GLLDARTATSHWYALRKL------------------ERQHRTRWIK-----DRRYVQDGNVVTTSGVTAS------------------- +----------------------NAGTETTDFIVPYAILKRSGVDVVAVSADEGTVEMPLRMLAD------T--------T-------FDRFDATVPAGADVVIVPALHR-----ADRPAVLAWLRKQAAAGATMVAICDGAEVLANT-------GLLRQRTATSHWYSREGL------------------RRRFETKWVD-----DRRYVMDGNVMTTTGVSAS------------------- +----------------------NAGTETTDFIVPYSILKASGVDVVAVSVDAGPVEMPLRMLAD------T--------T-------FDRFDAAIPAGADVVIVPAMHR-----ADRPAVSAWLQKQAAAGATMVAICDGAKVLAHA-------GLLRHRTATSHWYSRDGL------------------RRQFDTTWVD-----DRRYVMDGSVMTTSGVSAS------------------- +----------------------NTGTEITDFLVPYALLSQAPTKVFAVSGEPGPISWPLKAEPD------M--------D-------LAKFDKAWPDGADLIVVPAVHD-----PADKRLTAWLRQQAAKGAFIASICDGSLLLAES-------GVLDGHEATGHFYTEDNR------------------RTDYHVTWLA-----NRRYVEDGRFLTSSGVSAS------------------- +----------------------NAGTETTDFIVPYSILKASGVDVVAVSADAGAVEMPLRMLAD------T--------T-------FERFDAATPAGADAVVVPALHR-----ADSPAVLAWLRKQAAGGATMVAICDGAEVLANA-------GLLRHRVATSHWYSRDGL------------------RRRFDTTWID-----DRRYVMDGNVMTTSGVSAS------------------- +----------------------NAGTETTDFIVPYAMLKASGVDVVTVSADEGEVEMPLRMLAD------T--------T-------FDRFDAATAAGADVVIVPALHR-----ADGPAVLAWLRKQAAAGATMVAICEGAEVLANA-------GLLRHRTATSHWYARDGL------------------RRRFDTTWVD-----DRRYVMDGNVMTTTGVSAS------------------- +----------------------NAGTETTDFIVPYAILKASGADVVAVSADEGAVEMPLRMLAD------T--------T-------FDRFDATVPSGADVVIVPALHR-----ADRPAVLAWLRKQATAGATMVAICDGAEVLANA-------GLLRRRTATSHWYSRDRL------------------RRRFDTTWVD-----DRRYVMDGNVMTTTGVSAS------------------- +----------------------NAGTETTDFIVPYAILKTSGADVVAVSADAGAVEMPLRILAD------T--------T-------FDRFDADVPLGADVVIVPALHR-----ADRPAVLAWLRKQAAAGATMVAICDGAAVLANA-------GLLRDRIATAHWYSRDGL------------------RRRFDTAWVD-----DRRYVMDGNVMTTSGVSAS------------------- +----------------------NAGTEVTDFLVPYGILNQA-VDVFAVAPTMDPVAWPSSVRPD------A--------D-------FAGFDAQFPDGADIVIVPAMHD-----PEDPAMLAWLRAQEAKGALMVSICEGASVLAAA-------GLLDGRRATGHFYEHESR------------------VERYAVDWQR-----NIRYVEDGKRISSAGVSAS------------------- +----------------------NSGTELSDFVVPFGILSRSKAKVIAVSLLPGTVPRPLRLEMQ------Q--------T-------TAQFDAGYREGADYVIVPAMMN-----ETDPSLLAWIKAQAAKGSTIVSICNGAIVVANT-------GLMNGHRATAHWGTESLR------------------LANYDVRWEK-----NIRYVADGKIVSSSGISAS------------------- +----------------------NEGTVISDFVIPFGVMARSNADVVSVSVMPGPVKQPLTFELQ------S--------T-------IADFDKAHPEGADYLFVPAVEN-----FSDPNLIKWVKAQGAKGCTVISICYGALVVAKT-------GLFDGHRATSHYSNEEMR------------------AKLFKVNWQK-----NIRYVADGKVASSAGVSAS------------------- +----------------------NEGTIISDFCIPFGVMARSGADVMSVSVKPGPVKQPLTFQLQ------A--------T-------VAEFDRRHPEGADYIFVPAVEN-----DSDPNLLAWIKAQAGKGCTVISICYGAMAVANT-------GLFDGHRATSHYSNEGFR------------------AKRFKVIWQK-----NIRYVADGKVVSSAGVSAS------------------- +----------------------NEGTIISDFVIPYGVMARSGADVVSVSVKPGPVKQPLTFELQ------S--------T-------IDAFDKRYPEGADYLFVPAVEN-----FSDPDLLKWVKSQGDKGGTVISICFGALVVAST-------GLFDGHRATSHYGNEEMR------------------AVRFKVKWEK-----NIRYVADGKRVSSAGVSAS------------------- +----------------------NAGTELTDFVIPYAVLQRSGVDTFAVSTSPGPMQRPMRLQPD------L--------D-------VVGFDRRFPEGADYVVVPAIVQ-----SKDAALLAWIRAQHAKGATIVSICDGALVVANT-------GLLKGHRATAHWATEGHR------------------RDAYDTDWVA-----NTRYVIDGTMASSAGISAS------------------- +----------------------NSGVEVSDFLVPFAILSRAGLDVSAVTLEAGPLSFTFRIETD------T--------T-------VAQFDAVHPDGADYVIVPAQ-------AATPRLIAWLKQQSRQEATIVTICNGALVAAKM-------GTFDGRRATAHWSSGATR------------------KKQYAIHWTP-----NQRYVADGNWVSTAGVSAA------------------- +----------------------NAGVEVSDFLVPFAILSRAGMDVIAVTLDEGPLAFTFKITTD------T--------T-------VAQFDATQPEGADYVIVAAQ-------ASEPRLLAWLKQQSAHGATIVTICNGALIAAQM-------GVFDGRRATAHWWTGASR------------------VEKFAIRWTP-----NRRYVADGTWISTAGVSAA------------------- +----------------------NQYTELTDFVIPYAVFQRSNAQVYMLAPTKGKLNFPLSIEIE------T--------S-------LSDFDLLHPEGSDIVIVPALHN-----SENKTIIQWIQNQSKKGATIVGVCDGVWTMGYA-------GLLKNQRATGHWYSQDGL------------------TKTFDTIWQK-----NKRYIQDRNTITTTGVTAS------------------- +----------------------NQYTELTDFLIPFGVLKRAEGEVSLIAPNKGRMDFPLSIEIT------T--------S-------IADFDRLYPEGADIVIVPAIHN-----SNNKIIIHWIQNQNKLGATIVGICDGVWTLAHA-------GLLKDKHATGHWYSLPDL------------------SKSFDTIWTK-----NKRYLQDKDVITTAGVTAS------------------- +----------------------NKYTELTDFIVPYGVLKRANAEVYAVAPNKGKMEFPLSIEIT------T--------S-------IEDFDTLHPEGADLVIVPAIHN-----MENKTIIQWIQKQNKLSASIAGICDGVWTLAHA-------GLLKDKKATGHWYSIPEL------------------TKSFDTDWIK-----NKRYLQDKNIITTSGVTAS------------------- +----------------------NQYTELTDFLIPFGILKRSGVKIHALAPNRGIMNFPLSLEIE------T--------S-------LDDFDSLHPEGADLVIVPAIHN-----AKNKTIIQWIQNQSKRGATIVGICDGVWTLGHA-------GLLKDKNATGHWYSMDGL------------------KNQFDTKWTQ-----NRRYVQDQNIITTTGVTAS------------------- +----------------------NQYTELTDFIVPYGILKRSDAEMYAIAENKGKLDFPLSIEIN------M--------S-------LDDFDNLHPEGSDLVIVPAIHN-----AENKTIIRWIQNQFDRGATIVGICDGVWTLGYA-------GLLKNKHATGHWYSKEKL------------------SKTFDTVWIK-----NKRYVQDKNIITTTGVTAS------------------- +----------------------NYMTELTDYVVPYGVLTRSKAEVFAVGISLTPISYPLKIFPQ------E--------S-------ISSFDKKFSTGADYVIVPAIHH-----SENPILLEWLNLQASKGATIIGVCDGVWVLANA-------GLLKGKRATGFWYSLDDL------------------EKKFDTTWVR-----NRRYVVDQGIVTTTAVTAS------------------- +----------------------NYMTELTDYIIPYGVLTRSKADVYALGISATPMDYPLKMIPQ------E--------S-------ISSFDEKFPMGADYVVVPAVHH-----SENPILLKWLNGQALKGATVIGVCDGVWVVANA-------GLLKGKQATGFWYSLNDL------------------EKKFDTKWIR-----NRRYVVDQKIVTTTAVTAS------------------- +----------------------NANTELTDFVVPYGVLKRADADVVAVGTQAGPIQFPFRVEPD------T--------T-------VAAFDARFPGGADYVVVPAVHE-----DDDPHLLTWVRQQWAKGATVIGVCDGVWVLARA-------GLLAGRRATSHWYARDAL------------------ARQFQTQWVS-----DRRYVVDDRVVTTTGVTAS------------------- +----------------------NTFTELTDFVIPYALLKEANADVFTVAIRPGPIQFPFKVEAD------M--------T-------ASNFDRLYPLGADYILVPAVHE-----TDNPELLRWIQEQQAKGSTIVGICDGVWVLGHA-------GLLDGHYATGHWYSREDL------------------EEQYKASWVQ-----DRRYVADGKIVTTTGVTAS------------------- +----------------------NQMTELTDFVVPLGVLRRAGTKVLAVATDPGTVQMPLSLRAE------A--------S-------IDEFQRQFPQGADYLIVPAVHD-----SQKPRLLDFIRQQAALGANVIGICDGVLPLAYA-------GLLDGRRATGHWYSREQR------------------LSDFTTLWQE-----NRRYVVDGRLMTTAGVSAA------------------- +----------------------NRMTELADYVVPLGVLRRAGTQVLALATEAEPIEMPLSLQPD------A--------S-------IAEFRQRFPQGADYLIVPAVHD-----SRDPLLLDFIQQQAALGATLVGICDGVLPLAHA-------GLLQGRRATGHWYSRRQR------------------LKDFDTLWQE-----DRRYVVDGALMTTSGVSAA------------------- +----------------------NANTELTDFVVPYAVLKRSGAEVWALGLDPGPIRFPLRAQPD------A--------D-------IAAFDAHYPDGADYVIVPAVHE-----DADPRLSAWVRAQAGKGAVVIGICDGVWVLARA-------GLLDGRQAVSHWYSRSTL------------------ARDFAVRWRQ-----DRRYIADGGVVTTTGVSAS------------------- +----------------------NANTELVDFVVPYAVLKRSGAEVWALGIESGPIRFPLSARPD------A--------D-------VAAFDQRHPQGADYVIVPAVHD-----DADPRLLSWVRSQSQKGAVVIGICDGAWVLARA-------GLLDGRQAVSHWYSRGAL------------------ARGFSVQWRQ-----DRRYVANRNVVTTTGVSAS------------------- +----------------------NANTELTDFVVPYGVLKRADADVIALGTQPGPMQFPFRLEPD------S--------T-------IDAFDARFPDGADYVVVPAVHE-----DDDPRLLAWVRQQWAKGATVIGVCDGAWVLARA-------GLLAGRRATSHWYARDAL------------------AKQFQTQWVS-----GRRYVADGRVVTTTGVTAS------------------- +----------------------NFMTELTDFVIPYGVLTRSQADVFALGTEIGTMNFPMKIEVQ------E--------S-------LSSFDQKFPEGADYVIVPAVHR-----SENAVLLKWLNIQSSKGATVIGVCDGVWVVANA-------GLLNGKKATGFWYSLNDL------------------EKKFNTTWIR-----NRRYVADGKIVTTTAVTAS------------------- +----------------------NSSTELTDYVIPYGVLAESGAQVLAIATQAGPMQLPLKLQPQ------A--------T-------IAEFDSQFPEGADYVIVPAVIR-----RKDPTLLAWVNAQAKKGTTIVGVCDGVWVLANA-------GLLTGRKSVCHWFSYDSL------------------KKKFQTEWLQ-----NTRYVSDGSIITTTGVTAS------------------- +----------------------NGGTELTDFAIPYGVLARSGAEVIAVATQSGPMTRPLRIQPR------D--------T-------ITSFDARYPEGADYVIVPAVVK-----PNDVTLVSWVAAQGAKGATIVSICDGALVAANA-------GVFKGRRATAHWATGDYR------------------RQHYDTAWQD-----NVRYVADGRVISSAGVSAA------------------- +----------------------NYYTELTDYVVPYGIVAESGADLVALATKPGPIRFPMNLIPD------E--------T-------TAQFDQRVPEGADYVIVPAVHR-----DSDPALIAWVAGQAKKGATVIGVCDGVWVVARA-------GLLDGRRATGHWYSMDDL------------------RKKFDTRWVD-----GKRYVSDGKVVTTTGVTAT------------------- +----------------------NRMTELTDFMIPYGVLTSSKAKVIAVFPRTGPVQFPLKIEAE------I--------S-------FDLFESEYPDGADYVIVPAVHY-----SDDPVLLSFVQKQSAKGSTILGICDGVWVLAKA-------GVLKEHKATGHWFSFSKL------------------EKEFETRWIK-----DTRYIADRKIVTTTGITAS------------------- +----------------------NEYTELTDFLVPYGILKQAEADVHALSTNPGPIRFPLVLETG------E--------T-------LSYFDSKYPEGADYVVVPAMHN-----SENPVVSSWLKSQASKGATVIGICDGVWILAHS-------GLLQEKAATGHWYSFPDL------------------EKKFSTKWIR-----NRRYVIDGKIITTTGVTAS------------------- +----------------------NRMTELTDFMIPYGILTSAKAKVISVFPKIGPVQFPLKIEAE------K--------S-------FDQFDSEYPEGADYVIVPAVHY-----SEDTTLLSFVRKQSAKGSTIVGVCDGVWVLANA-------GILKDHKATGHWFSFSKL------------------EKEFETKWTK-----DRRYVSDRKIITTTGITAS------------------- +----------------------GAGAETTDFLIPYGVLKEAGADVIGLSTADAPLQMMVKIQPD------Q--------T-------TARFDAAQPAGADIVIVPAQHH-----PKSPALIAWIRKQAAQGAVIVSICEGARVVAAA-------GLLDGKRATTHFAALEQL------------------EKAYKTTWVR-----DRRWVQDGRIISTTGVSAS------------------- +----------------------NAGTETTDFVIPYGVLKESRADVLAVSTEPGTIKMPLQVRAD------T--------T-------TAEFDASTPDGADILIVPAMHR-----TDRPSLLAWVRAQSAKGALVVSICDGAWILANA-------GLLRDRMATSHWYSLSEL------------------KKQNNTTWVR-----NRRYVIDRNVMTTTGVSAS------------------- +----------------------NAGTETTDFLVPYGVLKESGMEVIAVSTRPGRVKMPLEIQAQ------M--------T-------TAEFDLATPEGADILVVPAMHR-----ADDPALLAWVRKQASAGARIVSICDGAWVLANA-------GLLRDRVATSHWYSLASL------------------KRQYDTTWVQ-----GRRYVADRNVMTTTGVSAS------------------- +----------------------NAGTETTDFIVPYSILKTSGADVVAVSPDATEVEMPLRMRAD------T--------T-------FERFDAATPAGADVVIVPAMHR-----ADRPAMLAWLKKQAAAGASMVAICDGAEVLANA-------GLLRHRTATSHWYSRDGL------------------RRRFDTDWID-----DRRYVIDGDVMTTSGVSAS------------------- +----------------------AEGTNIADTLAPYEVFARSGVNVFLVAERAEPVMGGLTVLPQ------R--------T-------FAQIDEMTGGGPDVIVVSQMHG-----DRS-GEMRWVRDSHDPGTVVMSVCVGAADVADA-------GILDGRRATTHWLKLVGL------------------RRDPDTEWVD-----SVRFVEDGPTISSAGVLSG------------------- +----------------------NEGTETTDFLVPHAVLQLAQGVVEAVASRAGAVTMPLQVEVP------R--------S-------FAAFDSVYPQGADIVVVPALHT-----EDDPAVLAWLQAQAAKGAVVVGICSGARVLGRA-------GLLEGRRFAGHWYDRSTL------------------LRRHGAVHVP-----GQRYVADGPVVTTTGVSAS------------------- +----------------------NDGTETTDFLVPFGILSRANVEVVTVSLRSGPVTMPLTIRAQ------S--------T-------IDEFDRAHGRGADYVIVPAMHV-----EDDPGIVQWILSQRAKGATILGVCSGARVLGHA-------GLLDGRKATGHWDDVDRL------------------RSKYSMQWVP-----NRRYVADRGVVTTTGVTAS------------------- +----------------------NIGTETTDLMIPHAILTRSGADVVVVSPLAGSITMPLSMTSQ------Q--------T-------LDAFDAMHPEGADYVIVPAFHG-----EGDARIIAWIKKQFAGDAFIAGICEGAKVLGKA-------GLLDGRDATTHWYAIDDL------------------RSAHTLRWIR-----DRRYVVDRSVMTTTGVTAS------------------- +----------------------NRMTELVDFLVPYGVLNRAGAEVMALSTDEGPLNMPLRVRAQ------M--------T-------TAEFARRYPQGADYLIVPAVHD-----SGDSGLVQFVATQAAKGAVIVGICDGAKVLAQA-------GLLDGRQATAHWYSRRQR------------------ERDFAVRWQN-----GRRYVVDGKRVTSSGVSAA------------------- +----------------------NEGTETTDFLVPYGVLRQARGQVEAVAVQAGDVTMPLRIVPD------T--------T-------LAAFDARHPRGADIVIVPAMHD-----ERDPRVLQWLQRQAAQGALIVGICSGARVLSQA-------GLLKGRRFTGHWFDRDDL------------------RSANTGRYVA-----NVRFLHDDGIVTTTGVSAS------------------- +----------------------NDGTETTDFLVPYGVLKRAGGQVEAVAVEAGDVTMPLRIVPD------T--------T-------LTAFDARYPRGADVVIVPAMHV-----DNDPRVLQWLQRQAANGALIVGICSGAKVLSQA-------GLLREKRFAGHWYDRDDL------------------RKDNTARYVS-----DVRYLYDDGIVTTTGVSAS------------------- +----------------------NEGTETTDFLVPYAVLRRAGAQVEAVAVESGEVTMPLRIAPD------T--------S-------LADFDARHPNGADIVIVPAMHV-----DDDARVLAWLRRQASQGALIVGICSGAKVLSHA-------GLLQRKRFTGHWYDRDDL------------------RKANEGRYVP-----DVRYLYDDGVVTTTGVSAS------------------- +----------------------NESTETTDFLLSHAVLQRSGAQVEAVAPRKGPVAYPLQIEVA------Q--------D-------LGSFDRAHPGGADYVIVPALDD-----ADDPAISRWLQQQTAKGARIVSVCAGALIVGRA-------GLLDGRRFVTHWHFRKDV------------------LRRHTATYVP-----HQRYTVDGNIATTTGITAS------------------- +----------------------NEGTETTDLLLPHAVLQRAGADVQVVAPRRGPVGYPLEIEAT------Q--------D-------LAGFDRTYPSGADYVIVPAMHT-----DDDPTVTTWLRRQAEQGARVIGICSGARVVGRA-------GLLDGRRFTGHWYDRGKL------------------RRRHGATYVP-----HRRYVIDHGVATTTGITAS------------------- +----------------------NEGTELTDLLLPHAVLQRADAEVRIVAPRAGRVTFPLQVEGA------Q--------D-------FATFDRAHPAGADYVIVPAMEP-----ADAPAVRAWLQQQASRGARVIGVCSGALVLAQA-------GLLDGRRFAGHWYDRGTL------------------R-QRGATHVP-----DRRYLVDRDVATTTGITAS------------------- +----------------------NEGTEMTDLLLPHAVLKRADADVQIVAPRSGRVNYPLQVEGA------H--------D-------FASFDRANPLGADYVIVPAMIV-----EDDPAVAAWLKQQAARGARVIGVCSGALVVGHA-------GLLDGRRFAGHWFDRKTL------------------KKRHGATYVP-----HQRYVMDRDVATTTGITAS------------------- +----------------------NEGTEMTDLLLPHAVLRRADAEVRIVAPRAGRVSYPLEVDGA------Q--------D-------FAAFDRLHPAGPDYVIVPAMIA-----DDNPEVAAWLQQQAARGARVIGVCSGARVVGRA-------GLLDGRRFAGHWYDRSTL------------------LERHGASYVP-----HQRYVVDRGVATTTGITAS------------------- +----------------------NDATEVTDYLVPAGILRRAGADVMLLATGPGPVRYPLRVRPD------A--------T-------IADFDRARPQGPDYVIVPAMSR-----E-DPQLLDWLRRQADSGATVVAVCAGARVAAAA-------GLLDGKRAVTHWYYLPGM------------------LKRHDIRHVP-----DRRMVADRGVATTTGITAS------------------- +----------------------NAGTEITDFLVPHAVLARSGARVQAVALRRGPVALPLRVEVP------C--------G-------LDDFDRQHPQGADCVVVPAMQV-----DDDPALLDWVRRQSAQGAAIVGVCSGARVLGRA-------GLLDGRGFTGHWADRRTL------------------QARHTARHVP-----GQRYLADRGVVTTTGVSAS------------------- +----------------------NDATETNDYIATTGILRRADADVVMLATGPGAVRYPLRVQPD------A--------T-------IAAFDADHPQGADYVIVPAMSR-----DDDPVVMAWLQDQFRKGARIIAVCAGAKVVAAA-------GLLDGRRATTHWYYRAEM------------------LERNGIDYAA-----NRRMVFDGKVVTTTGITAV------------------- +----------------------NDATETNDYITTTGILRRANADVVMLATGPGPVQYPLRVEPD------A--------T-------IAEFDAEHPEGADYVIVPAMSR-----DDEPVVLAWLQDQSRKGAKILGVCAGAKVVGAA-------GLLDGKRATTHWYYRGEL------------------LKRSTIDYVA-----DRRMVADGNVVTTTGITAA------------------- +----------------------NDATETTDYLLPTSILRRADADVEMLATAAGPVQFPLAVEPD------A--------T-------IAEFDALNPEGADYVIVPAMSR-----DDDPKVMAWLQAQKNKGAIIIGVCAGAKVVAAA-------GLLDGRRATTHWYYLKDM------------------LRAHTITHVP-----DRRMVIDEGIVTTTGISAS------------------- +----------------------NPGTEVSDFLSAYGVLARSGAEVTVVAEKDERVRYPLSIDPQ------E--------T-------MAAFDARYPEGADYVVVPAMDP-----GADPFIAEWIVAQHEKGAKIISICNGSRMIGTA-------GLLDGRRATGHWSAAKEL------------------RDKYTMEWVP-----DRRYVIDDGVATSTGITAN------------------- +----------------------KEGSETTDTIVPHAVLSLSGADVHVVAASSYPVEFPLTIVPQ------M--------T-------FEDFDDRYREGADYVIVPASHR-----IDSPKLVPWIAQQAGKNATVIGICAGARTVAAA-------GLLRGRRGTTHWYEVEDL------------------LKEEGLIPVT-----DRRYVVDDGIVTTTGVTAS------------------- +----------------------NQATELSDFFSAYGVLKRADAEVTVVAERAEPVQYPPKITPE------A--------T-------IADFDAQHPEGADYVVVPAMDP-----GTDQVIADWLVAQHKKGAKIISICNGSRMIGFA-------GLLDGRRATGHWSAVAEL------------------RQKHTMTFVP-----DRRYVVDDGVATSTGITAN------------------- +----------------------NDMTETTDYLMPYGILARADADVLTLATQQGPVTYPLKVQPH------A--------T-------IADFDAAHPDGADYVIVPAMSR-----DDDATVLQWIRSQAGKGAIVIGVCVGATVVANT-------GLLDGKRATTHWYSVRDL------------------RK-HTIRYAP-----DRRLVVDQGVATTTGITAS------------------- +----------------------NDMSETTDYLMPYGILARADADVLTLGTEPGPVAYPLKVQPH------A--------T-------IAEFDAAHPDGADYVVVPAMSR-----EDDAVALQWIKSQASKGAIVIGVCVGAKVVANT-------GLLDGRKATTHWYSVPDL------------------QK-HDIRYVA-----DRRLVVDRGVATTTGITAS------------------- +----------------------NDATETTDYLLPYGILKRADAEVVSLATAPGPVRFPLTVQPD------A--------T-------IAAFDAAHPQGADYVIVPAMSR-----DNDPAVIAWLRSQAGKGAVIIGICAGAKVVAAA-------GLLNGKRAVTHWYYLDEM------------------RKIDTISHVP-----DRRMVADGGVVTTTGITAS------------------- +----------------------NDATETTDYLMPYGILRRADADVVALATESGPVTYPFKIVPD------M--------T-------VADFDAEHPDGADYVIVPAMSR-----DDDPAVLQWLKRQADKGAMIVGICAGAKIVGEA-------GLLDGKKATTHWYYVDEL------------------RRAHAIHYVA-----DRRMVVDKGVATTTGISAS------------------- +----------------------NDGTETTDYLMPYGILRRADADVVALATQPGPMRHPLQIEPD------A--------T-------TAAFDAEHPDGADYVIVPAMMR-----DDDAEVLKWIKSQAAKGAMVIGICAGAKVVGAS-------GLLDGKRATTHWYSVGEL------------------REKHAIHYVA-----DRRFVVDQGVATTTGITAS------------------- +----------------------NDATEVTDYLMTYGILRRADADVLALATGAGPVSYPLKVEPD------A--------T-------IAEFDAQNPDGADYVVVPAMTP-----DDDPAALEWIKSQSAKGATIVSVCAGAKVIAEA-------GLLDGKRGTTHWYYLKEL------------------REKHKLDYVA-----DRRLVVDQTVATTTGISAS------------------- +----------------------NDGTEITDYLMPYGILRRADADVVALATQPGPMVYPLKVEPQ------A--------T-------IADFDAQHPEGADYVIVPAMVR-----EDDPAALRWIRSQAEKGAVIVGVCVGAKVVAAT-------GLLDGRKATTHWYSLEAM------------------LREHSIRHVA-----DRRFLVDGRVATTTGISAS------------------- +----------------------NDATETTDYLMPYGILRRADADVVALATGPGPVKFPLQVEPD------A--------T-------VAEFDAQHPEGADYVIVPAMMR-----DDDADVLKWIKSQAAKGATIIGICAGAKVVGAS-------GLLDGKRATTHWYSLNEL------------------REKHTIRYVA-----DRRFVVDQDVATTTGITAS------------------- +----------------------NDATETTDYVMPYGILRRADADVVALATGPGPVKYPLTVEPD------A--------T-------IADFDARHPQGADYVIVPAMSR-----DDDPAALAWIRAQAAKGAMVIGVCAGAKVVGEA-------GLLDGKRATTHWYYLKEL------------------RKEHSIRYVA-----DRRLVADQGVATTTGISAS------------------- +----------------------NDGTETTDYLMPYGILRRADADVVALATRPGPVQHPLRVEPD------A--------T-------IAAFDAQHPEGADYVIVPAMMR-----DDDPDVLRWIRAQSAKGAMVIGVCVGATVVGAS-------GLLDGKRATTHWYSLNEL------------------RQKHTIRYVA-----DRRYVVDRNVATTTGITAS------------------- +----------------------NDATETTDYLMPYGILKRADADVVTLATKPGPVTFPLKVEPQ------A--------T-------TAEFDAQHSDGADYVIVPAMSR-----DDDPDALQWIRSQSAKGAIVIGVCAGAKVVGDA-------GLLHDRQATTHWYSVKEL------------------RGKHTMRYVR-----DRRLVVDKGVATTTGITAS------------------- +----------------------NDATETTDYLMPTGILRRADADVVMLSTEPGPVKYPLTVEAD------A--------T-------IEAFDARHPKGADYVIVPAMSR-----DDNPAIMAWLRKQAEHGAVIIAICAGAKVAAAA-------GLLDDRRATTHWYYLGDL------------------LKHHSIRYVA-----NRRIVVDRGVATTTGITAS------------------- +----------------------NDATETTDYLVPYGVLRNADADVVTLSTGDGPVRYPLTVRAQ------A--------T-------VAQFDQRNPQGADYVIVPAMSR-----DDDPTVLAWLRSQREKGAIIIGICAGAKVLAGA-------GLLENRRATTHWYYLKTL------------------LRDYNIRYVP-----DRRWVVDDGVATTTGITAS------------------- +----------------------NDATETTDYLMPYGILRRAEGDVVALATGPGPVTYPLKIEPD------A--------T-------VAEFDTLHPEGADYVVVPAMSR-----DDDPAVLRWVRSQADKGAVVIGICAGAKIVGEA-------GLLDGRRATTHWYYLEEM------------------SEKHALRYVA-----DRRVVVDEGVATTTGITAS------------------- +----------------------NDGTETTDYLMPYGILRRADAEVIALATAAGPVTYPLKVEAQ------A--------T-------IADFDARYPEGADYVIVPAMYR-----DDDPTALQWIRSQAAKKAIIISVCAGAKVVAAA-------GLLDGKRATTHWYYLDEL------------------RKEHAVRYIA-----DRRLVVDRGIATTTGITAS------------------- +----------------------NDATETTDYLLPYGILRRADADVVTLATAPGPVTFPLKVEPH------A--------T-------TAEFDAQHPDGADYVIVPAMSR-----DDDPAALQWIRNQAAKKAIVIGVCAGAKVVGDA-------GLLHGKRATTHWYSIKEL------------------RGKHTMRYVE-----DRRLVVDDGVATTTGITAS------------------- +----------------------NNATETTDYLMPTGILRRADADVVTLSTEPGPVKYPLTVEAD------A--------T-------LAAFDARHPEGPDFVIVPAMSR-----DDDPAIMAWLHKQAEHGAVIIAVCAGAKVAAAA-------GLLDGRRATTHWYYLKAL------------------LGSRTIRYAA-----DRRMVVDRGVATTTGITAS------------------- +----------------------NDMTETTDYLMPYGILKRADADVVTLATGPGPVAFPLKVEPD------A--------T-------IAAFDAAHPDGADYVIVPAMSR-----DDDPAVMQWVRQQAEKGAVIVAVCAGAKVLAST-------GLLDGRRATTHWFYLKNW------------------RSKHEIRYVA-----DRRIVVDHGVATTTGISAS------------------- +----------------------NDATETTDYLMPYGILRRADADVSLLATAAGPVKYPLTVEPD------A--------T-------IADFDRRHPDGADYVVVPAMSR-----DDDPAVLQWLRSQADKGAIILGICVGAKVVAAA-------GLLDGRRGTTHWYSVGEL------------------RQRHAMRYVA-----DRRLVVDGKVATTTGITAS------------------- +----------------------NEATETTDYLVPAGILRRADADVVMLATGPGTVTYPLKVVPD------A--------T-------LAQFDAAHPEGADYVIVPAMSR-----DDDPAVLDWLKSQAAKKARIIGICAGAKIVAAA-------GLLDGRRATTHWYYLREM------------------LGRSTTTHVA-----DRRMVSDEAVTTTTGISAS------------------- +----------------------NDATETTDYLMSYGTLKRADADVRALATQPGPVTFPLKIQPE------A--------T-------VAQFDERYPDGADYVIVPAMSR-----DDDPQALQWIRQQAAKGSIIISVCAGAKVVAAA-------GMLDGKAATTHWYYLDEL------------------REQHEVRYVK-----DRRIVIDQGVASTTGITAS------------------- +----------------------NDATETTDYLMPYGILRRSGADVVALATGPGPVKYPLTVEAD------A--------T-------TAQFDARHADGADYVIVPAMSR-----DDDPAVLQWLREQAAKGAVVIGVCAGAKVVGAA-------GLLDGQRATTHWYFLDEL------------------RERTSIRYVA-----DRRFVVNPGVATTTGISAS------------------- +----------------------NDATETTDYLMPYGILKRADADVMTLATHDGPVSYPLTVQPD------T--------T-------VAQFDRRYPDGADYVIVPAMSR-----DDDPAVMAWLQQQKAKGAIIIGVCAGAKVVAEA-------GLLNGKRATTHWYYLKEL------------------LQKHDINYVA-----NRRWVIDNGVVTTTGITAS------------------- +----------------------NDATETTDYLLPYGILKRAGADVMALSIKDGPVRYPLTVRAD------A--------T-------AAQFDRRYPTGADYVIVPAMSH-----DNDPAVIAWLRHQKAKGAIIIGVCAGAKVVAEA-------GLLDGRRATTHWYYLNTL------------------LENHAIDYVA-----NRRWVVDNGIVTTTGITAS------------------- +----------------------NDATETTDYLMPYGILRRADGEVTALATQPGPVKYPLQVEPD------A--------T-------IAQFDAQHPQGADYVLVPAMSR-----DDDPAVLQWIRSQAAKGATVIGICAGAKVVAAA-------GLLDGKRATTHWYYLEDL------------------LDKHTVRYVA-----DRRIVVDGRVATTTGISAS------------------- +--GKRIAILATN------------GFERAELEVSQDRLKKAGATVDVVSLAAGEIK-----------GWDKK-------DWGRPVKVDKALEEASAPDYDAIVLPGGQINP-DLLRVEPKALFIKDIFDAKKVVAGI---------------------------------------------------------------------------------------------------------- +--GDRVLMFVAYN-----------DVWWSEYKVMYETLDALGYDVDVRSSAGGSASTYLGLTLDEWSGGTVDAFEETGEAWNSTWNDPIPIQDVSLDAYEAFVLVGGTGAIDYLYDAIAIDELVNDAIERGVPVIAQCHGAALVSYARIDGLGTSVLEGRSATGYHLGDG------------------------------------------------------------------------- +--SRKVLFFVSYG-----------NTYYSEYKVAYEGLRAAGFEVDVRSAATGSAESYASGDIEATAGSSTAQFQNFGSAWQSGYNTPIPIQDVDMSGYVALVSAGGTGSLDYRVDAEKLNSLALNALENGKPIYFQCHAASLPVFFRIPGLGISLLKNQEAAGYPEAQT------------------------------------------------------------------------- +----TLIFTLTNAHPYVRVVVLATGFDEIETVTVVHVLRAAGAHVTLASLSPGKLLGAHML----------------------RVKPDVDLLTGPTDPYDAVILPGGEAAVELMSASEELGRLLIEYEKYNKYIGAMGVSALALQQ-------HRIAYGALLTADPRVENKL-------------------SDFG--FIA-----SDDVVVDKTLVTCTGPGSAMQFALEMVEL--------- +--TKTALVVLAN------------GAEDVEFVASVDVLRRAGMKVLVASL-GDCVKTSHGL----------------------KIEGDILLKEVSQNNYDVIVFPGGLKGAENCRDSSHLAALLRAQHSSSKWIAAICAAPALVLQQ------QNFLENVRAVAYPSFQQ------------------------------------------------------------------------- +---------------------------EIETVITVDVLRRAGIAVTIAGLSDNYVKCSS----DI------------------KICVDAKFADANNQKYDAVILPGGPIGCKTFASSAEIGKLLQEQEKENRLIAAICAAPTALKAH-------GICKGKQITSYPDVKNEL----------------------------------------------------------------------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASVDESTNI-----V-----GSQRM-----------KIVADKCILDASDSKYDLIIIPGGPAGAERLHRCTTLKKLLKEQRQASRMYGGICYSPLILQK-------QGLLQDKTVTAHPSIVNQ----------------------LTCQVID-----RSKVVIDGNLITGKGLGTVMDFSLAI------------ +-----------------------------------------------------------------------------------------------PEAPTVLFAPGGISSTLNAMEDAETVDFLASRGARADYVTAVCTGALLLGQA-------GLLDGYKAATHWLARHT-------------------LDAFGTEAV------NARIVRDRNRITGGGVTAGI------------------ +-----------------------------------------------------------------------------------------------PKDLTVLFAPGGASGTLAAMRDDATRAFIADRGARAQYVTSVCTGALILGAA-------GLLQGYRATTHWAALET-------------------LADCGATPV------SERVVRDRNRITGAGVTAGL------------------ +------------------------------------------------------------------------------------------------PPLDVLLVPGGMGTRAPEAALAPHIKFVKDTYPSLKYIISVCTGASILGRA-------GILDGKQATTNKAAWDF-------------------ATQWGKNQP------SARYVHDGNVWSTSGVSAGT------------------ +------------------------------------------------------------------------------------------------PDLEVLLVPGGLGTRDTAA-SQHVVDFVKLQYPKLKYLLTVCTGSALAARA-------GVLDGRNATTNKQSFDE-------------------VVPLGPKIN------EARWVVDGNIYTSSGISAGM------------------ +--MSNLLVICAK---R---------YNGHELWTTLGVFQERGHSFEVVSQETL-IRDEMTLRPNTI---ERTV---------------YDVECHETADFDAVVVISGNMATEAYWTDDFVEGLLLEFKAADKVCAAICCSVPTLA---------PIAKGIKVSYFPLLRAK-----------------HRLRHYGVLPQN------VSLTVDGRFVTAENQMITQMWAEEICNV--------- +--MSKLLVICAK---R---------YNGHELWTLLDVVVHRGHSFEVVSQELL-IRDELTLRPNTT---ERTV---------------YTLDDHNVRNFDAICIVSGNMATEAYWDDAHVAGLLGAFKGADKVIAAICCSVPTLG---------PIVKGIKVSYYPLIRSR-----------------HRLQYYGAILQT------TSLTVDGRFVTAENQMMTEMWAEEICNV--------- +------------------------GTEEMEAVILAGVLRRAGADVTLASVEDGLE-----IEASYG---------T-------RIIADKPIAACADQVFDLVAVPGGMPGSVRLRDNEILQRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKGRKITCHPSFIG-------DLPT----------------FRA----VESNVQVSGELTTSRGPGTAFQFALSF------------ +----------------------------------------------------------------------------------------------------------------GLRDCKALEKMVKTHAEDGGLYGAICAAPAVTLAY------WGMLKGLKATCYPSFMEKF----------------------TAEVIP----VDSRVVVDRNAITSQGPGTAVEFALALVEK--------- +----------------------------------------------------------------------------------------------------------------SFA-C-----IKEQLQFSMKPYANRCKNPNIHNPY------DQITNSHHATGHPWFVEKF----------------------PPKVTA----VDANVVVDGNAVTGTGPATSMEFAMALVEQ--------- +----------------------------------------------------------------------------------------------------------------RLRDCDVLRKITCRQAEENSLYGAICAAPAVSLLP------WGLLKKKKFV----MQDNL----------------------P-RFWA----IKSNLQVSRGLTTSRGPGTSYQFALSLAEQ--------- +----------------------------------------------------------------------------------------------------------------RLRDNEILKRIMVRQAEEKRLYGAICAAPAVVLMP------WGLHKGRKITCHPSFIGDL----------------------P-TFRA----VESNVQVSGELTTSRGPGTAFQFALSFVEQ--------- +----------------------------------------------------------------------------------------KKIGNADPKDYDAVVIIGGHSG-DIMSTEEKVMDFIKAAYNNSAVIGGIGGGIIPIIAA-------GIIKGKECTGSVQV---------------SF----ILNKI-AKYKD------SQCVIDDRIITARDTLDTPLFMYTLCK---------- +-----------------------------------------------------------------------------------------------SNNYDALVVLGGHSA-DVMMTEVEVIDFIKAVYDKGAIVGAIDGGSIPLISA-------GIMSGKMATGNEVV---------------SF----MLKKI-GTFKN------VPIVKDGQVITARNTVDTPDFVRELCK---------- +-IVKTVLFALLDK---W-A--------DWEAAYALQMLGQNQFSNRVLSLTKDPVE---SIG-GFR------V--VPD----------CDLQSV-PADYDALILIGGMS--WRDTSAQQLKSLIESCLIDGKVLGAICDASAYLGTI-------GVLNSVRHTS--NDLN-------------------DLKAAGDAYTGEDNYVREQAVRDCNVITANGTA-ALEFAQEVLLA--------- +--MKTILLVLLDR---W-A--------DWEGAYALGMLAPGKYAVKTVSLTGEPVS---SIG-GVR------A--LPD----------FSVDGA-PEEYEALFLIGGLS--WREESARRVTPLVKDCLAKGRVLGGICNAAGFLGTV-------GALNQVRHTA--NDLG-------------------DLKRAGEAYTGEDRYLTRQAVRDQNIVTANGTA-ALEFAKEALLA--------- +-MKKVVLFVILDK---Y-A--------DWEAAYLILSLGQDEYSVKTVSLTKDIIQ---SIG-GFT------V--LPD----------YDIQSA-PTDFEGLILIGGMS--WRNESAQQVKLLVQNALNNRKVLGGICDASAFLGTI-------GVLNNVSHTS--NDLN-------------------DLKQAGNSYTGEEKYIMQQAVRDNNIITANGTA-SLEFAKEVMLA--------- +-MKKYVLFVILEP---Y-A--------DWEAAYALYMLGRGRFEVKTVSLTREPVA---SIG-GFR------V--LPD----------YDINSV-PSTYEALVLIGGLA--WRNEEARRIRPLVDQCRENGKVLGGICDAAAFLGAV-------GALNDAYHTG--NDLN-------------------DLKQAGEAYTGEQRYVMKQAVRDGKIITANGTA-PLEFAKEVLFA--------- +-MKKCILFVILEP---Y-A--------DWEAAYALQMLGQGMYEVKTVSLTKEPVC---SIG-GFC------V--LPD----------YDINSI-PADYEALILVGGMA--WRNEEARRIQPLVEKCLEKGKVLGGICDASGFLGTA-------GVLNNVNHTS--NDLN-------------------DLKQAGKAYTGEQKYVMRQAVRDGNIVTANGTA-PLEFAKEVLFA--------- +-MKKQILFVILEQ---F-A--------DWEAAYAVYMLGMGEYDVKTVSLSTDMVT---SIG-GFH------V--VPD----------HSIESV-PSDYEALILIGGMA--WRNENAGKIRPLVDSCLAEGKVLGGICDASAFLGTT-------GALNNVKHTS--NDLD-------------------DLKQAGGMYTGEERYVTRQAVRDKNVITANGTA-PLEFAKEVLLA--------- +-MRKTILFVILQQ---Y-A--------DWEAAYAITMLGQGQYEIKTVSLSKDAVQ---SIG-GFR------V--LPD----------YDIASI-PNDYEAVVLIGGMT--WRNENAQQVKTLVEDCYQNGKVLGGICDASAFLGTV-------GVLNDVTHTS--NDLN-------------------DLKQAGSIYTGETKYIAKQAVRDKNVITANGTA-TMEFAKEILLA--------- +-MKKTILFVILQQ---Y-A--------DWEAAYGINMLGDGSYEIKTVSLTNESIA---SIG-GFH------T--VPD----------YDIKSI-PSHYEALILIGGMT--WRDEKAKQVKPLVEECFKKGKVIGGICDASAFLGTV-------GILNNVNHTS--NDLN-------------------DLKKAGKSYTGEEKYIMQQAVSDKNVITANGTA-ALEFAKEVMLS--------- +-MKKMILFVLLDQ---F-A--------DWEAAYALKMLGEDQFSMKTVSLTRDKVE---SIG-GFH------I--LPD----------YDIPSV-PKDYEALILVGGMT--WRNEAALQVKHLVDECLKSGKILGGICDASGFLGVS-------GALNSVRHTS--NDVN-------------------DLKQAGDAYTGEKNYLQEPAVSDGGIITANGTA-ALEFAREVLLT--------- +-MKKTILFVILQQ---Y-A--------DWEAAYAINMLCQGQYDIKTVSLSKDFVQ---SIG-GFK------V--LPD----------YDISSV-PNDYEALILIGGMT--WRNENSKQVKTLVNDCLQKQKILGGICDASAFLATT-------GALNNVNHTS--NDLN-------------------DLKQAGSIYTAENKYISKQAVRDKNIITANGTA-TMEFAKEILFA--------- +---------------------------------------------------------------------------------------AKPFSKANPRKYDALVIIGGHSADV-MMTEDKVIDFIKAVSDRRGIVGAIGGGSIPLITA-------GIMNGKKSTGNRVV---------------SFML----EKIG-SFM------DVPIVRDGRVITARNTVDTPLFVRELCK---------- +---------------------------AHSFIHSYT-LASSLFAVTIATPGGGPLHFPETDA------NSRRWL----DDFAKPAAVPVAVESLDLTLFAALLIPGGAGTITDLPHNAAVAHLAMAFDRDKKLICAVGLGVSVLCASALLGGADWQFAGRCMTAVSQT--------------------------------------------------------------------------- +------------------------GTEPVEAAVPIDVLRRAGADVTVASADDGELVVEVMYGVRIV----------A-----DAL---VAGGDCAAAHFDLIVLPGGVPGAANLGGCAALEAMVRRHAAARGLYAAICAAPPLALAS------WGMLNGLKATAHPLFVDK----------FPP-----EV----AA-V------DASVVVDASAVTSRGPATSTEFALALVEQ--------- +---------------------------LLDVNGSLRMLLKANFNIITITQTGEHV---TSFTP--------------------QIANYYNFEN--CPDFDILFIPGGVG-TRDELENSVFLDFIKQRVPKVKYVLTVCTGSGLLAKT-------GLLDGKKATT------------------------------------------------------------------------------- +---------------------------AIDVVGPVDLLANAGFLEVHVGITKDPI---HLFTS--------------------AITLTTTVDE--CPELDIILLGGP-N-PVGFVLHPKYLDIIRRHINAGKLLFTTCTGSAVLAST-------GLLDGKNATI------------------------------------------------------------------------------- +------------------------GVHPFELGVVCEVFSLPVYDFAVASAEGSTLRTP----SGF------------------TVSTPYGLD--RLEEADLVVVPAGDSYVHRD-YPPELLDALRRAADRGARVLSVCSGVFVLGAA-------GLLDGRPCAVHWKHAEEL-------------------ARQPRAVVEP----DVLYVDADPVITSAGTAAGIDACL-------------- +------------------------PQSTFELGCAAEVFTQVRYAFGVCTERPGPVATL----AGY------------------AMVVPDGLD--ALDRADTVVVPGWLPP----EPTPAVVRALRRAHDRGARLVSICSGAFALGHA-------GLLDGRRATTHWARADQL-------------------AALPAVQVDP----DVLYVDHGDVATSAGAGAGIDLCL-------------- +---------------------------------MRGVGLPTRYGFGVCTEYPGPVATR----AGY------------------DMLVTKGLE--ALDGADTVVVPGWPRI----EPSPAVVRALRRAHKRGARVISICSGAFALAYA-------GLLDGRSATTHWALAGEF-------------------AARPAVHLDP----DVLYVDHGDVATSAGAGAGIDLCL-------------- +------------------------VQSTFELGCAVEVFAPTHYELTMCTETPGRVTTA----AGY------------------SIDVPTGLD--ALETADTIIVPGWLPV-D--VPTPRVIAALRRAHHRGARLVTICSGVFALAHT-------GLLDGRSATTHESRIGLL-------------------QKMPAVRVV-----ETLFVDHGDVATSAGAGAGIELCL-------------- +------------------------VQSTFELACATEAFDPRYYDFQVCAEQPGSVPTT----AGY------------------DIVVNEGLS--AVDDADTVIIPGWRPI----DLSSAVLRSLKRAHKRGCRLVTICTGAFALAQT-------GLLDDRRVTTHWACADRL-------------------GTLPRVQVDP----DVLYVDHGDVATSGGAGAGIDLCL-------------- +------------------------VQSTFELACATEVFDPRYYEFRVCTERPGAVPTT----AGY------------------DMLVTEGLA--AVDEADTVIIPGWRPY----DLSPAVLRALKRAHKRGCRLVTICTGAFALAQT-------GLLDGRRATTHWSRTGQL-------------------QALPRVEVDP----DVLYVDHGDVATSGGAGAGIDLCL-------------- +------------------------PQGLFELGCVVEVFPPARYDLTICAEEPGEVATS----AGI------------------GLTAAAGLS--AIDTADTVIVPGWRSP----D-PQAVSDALRRAHSRGCRLVTLCAGAFVLAHA-------GLLDSRRATTHWARTAEL-------------------QSRPEVLVEP----DVLYVDNGDIATSAGAGAAIDLCL-------------- +------------------------PQSTFELSCAAEVFGATRYTFDVCAERPGPVATY----AGY------------------DMVVTAGLD--ELERADTVLVPGWLPT----EPSPRVVQALRDAHSRGARLVSICSGAFALAAT-------GLLDGRRATTHWARVDEL-------------------AARPSIEVDR----DVLYVDHGDVATSAGAGAGIDLCL-------------- +------------------------PQSTFELACAAEVFRATRYSFGVCTENPGPVATR----AGY------------------DMLVTESLD--ALDRADTVIVPGWLPT----DPSPAVVRALRRAHGRGARVVSICSGAFALAHA-------GLLDGRSATTHWALADEF-------------------AARPAVRLDP----DVLYVDHGDVATSAGAGAAIDLCL-------------- +------------------------PQSTFELGCAAQVFLPTRYGFDVCTEHPGPVATH----AGY------------------DMLVTKGLD--TLDGADTVVIPGWPRI----DPSPAVVRALRRAHGRGARVVSICSGAFVLAHA-------GLLDGRSATTHWALAGEF-------------------AARPAVRLDP----DVLYVDHGDVATSAGAGAGFDLCL-------------- +------------------------PQSTFELACAAEVFPPTRYEFAVCTEHPGAVPTL----AGY------------------DMAVSRGLP--DLGTADTVVIPGWQHG----EAPPAVIDAVRQAHRRGARIAAICSGAFLLAQA-------GLLDHRRATTHWRMVAEL-------------------AARPDIQVEP----DTLYIDLGDIATSAGTAAGIDLCL-------------- +------------------------PQSTFELACAAEVFPPSRYAFTVCAERPGAVPTL----AGY------------------DMVVSEDLT--ALDAADTVVIPGMHQR----EAPPAVIEALQRAHRRGARTVAICSGAFLLAQA-------GLLAGRRATTHWRLAGEL-------------------AARPEVRVEA----EALYIDLGDIATSAGTAAGIDLCL-------------- +------------------------PQSTFELACAAEVFPPARYDFEVCAERRGSVPTL----AGY------------------HMAVDQGLS--ALAAADTVVIPGWQHS----GAPPAVIDALRQAHRRGARVVAICSGAFLLAQA-------GLLDHRRATTHWRMAAEL-------------------ADRPGVQVEP----DTLYIDLGDVATSAGSAAGIDLCL-------------- +------------------------GVHPFELGVVCEVFSLPRYDFAVVSAEGPALGTHV---GGL------------------TVTTPYGLD--RLEEADLIAVPAGDDFTTRV-YPPALLDALRRAVDRGARVLSVCSGVFVLGAA-------GLLEGRRCAVHWHHVDEL-------------------RRQPHAVVEP----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------GVNPFELGVVCEVFSLPVYDFAVVSAEGASVRAS----AGF------------------TLQTEHGLD--RLDAADLITVPAGASYTSRE-FPPEMLDALRRAVDRGARVLSVCSGAFVLAAA-------GLLEGRRAAVHWKHAEEL-------------------SRRPHLTVEP----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------GVNPFELAVVCEVFSLPVYDFAVASAEGRTLRSN----AGF------------------SLHVEHGLE--RLDSADLIAVPAGSHYASRP-FPPELLDALRRGVDRGARVLSVCSGVFVLAAA-------GLLDGRRCAVHWHHADEL-------------------ARQPRLTVEP----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------GVHPFELGVVCEVFSLPVYDFAVVSAEGPELGTHC----GF------------------TLSTPHGLE--RLEEADLIAVPAGESYVDRD-YPPELLAALRRAVERGSRVLSVCSGVFVLAAA-------GLLDGRRCAVHWHHAGQL-------------------ARRPRLAVEQ----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------GVHLFEMGVVCEVFSLPTYDFAVVSAEGPTLGTHV---GGL------------------TVSTPYGLE--RLDEADLITVPAGSEYVTRD-YPPELLDALVRAVDRGARVLSVCSGAFVLGAA-------GLLDGRRCSVHWRHAEEL-------------------ALRPRAVVEP----DVLYVDEGPVITSAGTAAGIDACL-------------- +------------------------EVAVFELGVLCELFTLPGYDFAVCGVDGGPVPSH----SGF------------------TITPSHDLA--PAWTADLVAVVPNDVR----QAPAEVLDVLRHAHDRGAWVMSVCTGAFTLGEA-------GLLDDRRCTTHWRYTDSL-------------------AARPRAKVDP----GVLYVVDGTVLTSAGTAAAIDCGL-------------- +------------------------GVAPFELGVLCELFSLPAYDFAVCSVDAKPVRSR----PGF------------------TIAPTHDLA--PAETADLVAVAPNDLR----PVPAEILDVLRRAHARGAWVMSVCTSAFTLGEA-------GLLDGRRCTTHWLHTAAL-------------------AARPRAEVDP----DVLYVADGTILTSAGTAAAIDSGL-------------- +------------------------EVAVFELGVLCELFTLPGYEFSVCSVGRAPVRTH----AGF------------------SMTPDHDLT--PAETADLIAIAPNDIQ----DPPAEVVEVLQRAHARGAWIMSVCTGAFTLGAA-------GLLDDRRCTTHWRHTDAL-------------------AERPRAKVDP----GVLYVVDDNILTSAGTAAGIDAGL-------------- +------------------------EVAVFELGVLCELFTLPGYTFSVCSVDGAPVRTH----AGF------------------SITPDHDLA--PAAEADLVAIVPNDTD----RPPEAVLDVLRAAHARGAWVMSVCTGAFVLGAA-------GLLDDRRCTTHWRHTEAL-------------------AARPSAKVDP----NVLYVADGNILTSAGTSAAVDCGL-------------- +------------------------QVAAFELGVLAEVFTFPSYRFDVCTADGGPVRSR----SGF------------------LLAPTADLK--VVEDADLVAVPAHADG----AVPEPVLAALRRAADRGAWLLSVCAGAFVLGEA-------GVLDERACTTHWRYTDEL-------------------QRRPAAQVQC----DSLYVQDGRLLTSAGTAAGIDACL-------------- +------------------------QVAPFELGVLAEVFTFPAYRFDVCGPNGAPVRTS----AGF------------------HLTPNADLG--PLEDADLVAVPAHAQG----TVPGPVLDALRRADARGAHLFSVCSGAFLLGEA-------GLLDDRECTTHWRYVDEL-------------------QDRPRARVRC----NSLYVQDGRLLTSAGTAAGIDACL-------------- +------------------------RVAPFELGVFAEVFTFPGYRFHVCTSDGGPVRTS----SGF------------------LVTPHTDLA--PVEDADLVAVPGHSDG----AVPPAVLAALRRAHARGAYVLSVCSGAFVLGEA-------GLLDDRECTTHWRYVDEL-------------------QRRPRARVRC----NSLYVADGRLLTGAGTAAGIDACL-------------- +------------------------RVAPFELGVLAEVFTFPGYRFTVCTVDGGPVRTS----SGF------------------HLTPHGDLT--AVDEADLVAVPAHPRD----SVPPAALAALRQAAERDAYVFSVCSGAFVLGAA-------GLLDGRECTAHWAHVDEL-------------------RQRPAARVRC----NSLYVADGRLITSAGTAAGIDACL-------------- +------------------------PTAVFELGVLCELFTLPAYEFSVCSVGGRPVRTQ----AGF------------------TISPGSDLA--PAEEADLVAIVPNNIA----GVPAEALGVLRRAAARGAWVMGVCTGAFALAQA-------GLLDGRRCTTHWRHADRL-------------------IAEPAAVVDP----DVLYVVDGTILTSAGTSAAVDCGL-------------- +------------------------NFSIFEFGTAFEVFSVPAFDFRVCTPEPGDVRLK----SGL------------------TMHVDLGLE--AAADADLVIMAPYGHD----QVPETVLDALRAAHSRGAWVMSICSGAFALARA-------GLLDGRRCTTHWHFSREL-------------------ASRPAALVDE----NVLYVQDGRIISSAGTAAGIDACL-------------- +------------------------NVSMFEFGTACEVFSVPAFDFRVCTPVPGSVTLE----SGL------------------SMNVELGLD--ATLDADLVIMTPYGGD----ALPEPVLAALRAADKRGAWVMSICSAVFALARA-------GLLADRRSTTHWRHSQEL-------------------ATSPGVEVDE----NVLYVQDGNIISSAGTAAGIDACL-------------- +------------------------NFSMFEFGTACEVFSVPGFEFRVCTPSPGEVPLK----SGL------------------SMNVSLGLE--ATKDADLVIMAPFGRD----QLPESLLDALRAADARGAWVMSICSGAFALARA-------GLLDGRRCTTHWHYSGQL-------------------AASPHALVDE----NVLYVQDGNIISSAGTAAGIDACL-------------- +------------------------NFSLFEFGTAFEVFSVPAFDFRVCAPEPGDVRMK----SGL------------------SLHVNLGLE--AAADADLVIMSPFGAD----RVPESVHEALRAAQARGAWVMSICSGAFALAKA-------GLLEGRRCTTHWRYSQEL-------------------AAKPGAKVDE----NVLYVQDGNIITSAGTAAGIDACL-------------- +------------------------HFSIFEFGTAFEVFSVPQFDFRVCTPVPGDIPLK----SGL------------------TMNVSLGLE--AAADADLVIMTPYGRE----EVPEEVLDALRSAHERGAWVMSICSGAFALARA-------GLLDGRRCTTHWHYSGEL-------------------AAQPKALVDE----NVLYVQDERIITSAGTAAGIDACL-------------- +------------------------GAAPFEFAIACEVFSVPAFNFKVCSVRPGGVDTK----TGF------------------SIEVPYGLE--AADSADLVVVAPYQNE----DVPEEVQHVLQRAHARGAWVLSLCSGAFVLAEA-------GLLDGRRATTHWHYSQQL-------------------ASQPLVKVDE----NVLYVEDDRIITSAGTAAGIDACL-------------- +------------------------GVTPFEFGVACEVFSIPAFDFSICTPSPGLVPTG----LGF------------------SISVEQDLA--ALETADLVIMPPFGID----AGQQEVHRALQSAHRRGAWVLSVCSGAFALAEA-------GLLNGRRATTHWLHAQRL-------------------AEQPEIHVDE----NVLYVQDGTIITSAGTAAGIDACL-------------- +------------------------GFSAFEFSVACEVFTVPPFRFAVCTEQAGPVGSR----QGF------------------SLTAEHRLD--RLDDADLVIVTPTELHRGA--AGERLRERLHAAVERGATVASFCSAAFTLAHA-------GLLDGRRATTHYRHAAEL-------------------ARRPLVEVVP----DVLYVEDGPVATSAGTSAGIDLSL-------------- +------------------------GLEPFGLGVLAEVWHNPVFDFRVCTERPGAVATE----YGF------------------EIVVRHDLA--SVADADVVAVAAKRDR----REEPAVSQVLREAHDRGAVIIASCSAVFTLGDA-------GLLDGRRSTTHWRYGAEL-------------------QEAPRTTVDT----DVLYIDDGDVVTGAGSAAGIDANL-------------- +------------------------GVEAFGLGSICEVWHNPVFEFSVCTPEPGRVRGS-----SY------------------DLFVEESLD--AAADADLVCIAPKRGY----RHHPAAIEAVRAAAGRGAYVSAHCTGAWLLGEA-------GLLDGRECTTHWRYGAEL-------------------QEAPEAVVRP----EVLYVLDDGVLTGAGSAAGIDASL-------------- +------------------------GAEPFGLGAICEVWHNPVFDVTVCTPEPGRVRGA----SGF------------------DLHVEHGLE--ALERADLVCIAPKREY----RHHPAAVEAVGAAGRRGAWVSAHCTGSWLLGEA-------GLLDGRRCTTHWRYGAEL-------------------QAAPEATVDA----DVLYVLDQNILTGAGSTAGLDASL-------------- +------------------------GAEPFGLGSICEVWHNPVFDFRVCTPRPGRVRGR----AGF------------------DLHVEHGLD--AIEDADLVCFSPKHEY----LFDPLVLDAARETYERGALVYAHCSAAFMLAEA-------GLLDGRECTTHWRYTDRM-------------------ARMPKAIVRP----DVLYVQEDNIMTGAGSAAGIDASL-------------- +------------------------EIHPFELGVACEVFSLPVYEFGLVGDRPGPMRTH----AGF------------------DVQVPYGPE--RLAEADLVIATAT--GIRDR-YPEALCEALRAAHDRGAHLLSICSGSFLLGAA-------GLLDGRRSTTHWQYADLM-------------------AERPLTTVEP----DVLYVDDEPVITSAGTAAGIDACL-------------- +------------------------EVHPFELGLACEVFSLPVYDFAVASDRPGKLRTH----AGY------------------SIDVEHGAE--RLARADLVIAAAT--TIRDE-YPAPLIEALRAAAERGARVLSICSGAFLLGAA-------GLLDGRRSTTHWRHTDRL-------------------AARPLTRVEP----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------EVHPFELGVACEVFTLPGYDFALAGARPGPHATH----SGF------------------AVDVPYGPE--RLAGADLAVVTAS--AIRPH-YPEPLLEALCAVVADGGRVLSICSGAFVLGAA-------GLLDGRRSTTHWRHSDEL-------------------AERPRTVVEP----DVLYVDDDPVITSAGTAAGIDACL-------------- +------------------------EVHPFELGVACEVFTLPGYDFAIAGARPGPHRTH----AGF------------------TIDVPHGPE--RLAAADLVVVTAT--TVSRE-YPEPLLEALRAAHARGARVLSICSGAFVLGAA-------GLLDGRRSTTHWRYSAEL-------------------AARPRTTVEP----DVLYVDEDPVITSAGTAAGIDACL-------------- +------------------------PVHPFELGVASEVFSLPVYDFALAADRSGRLATH----AGF------------------GLDVPYGPE--RLAEADLVVVTAV--GRRAE-YPPALTEALRAAVERGARALSICSGSFLLGAA-------GLLDGRRATTHWKHTDEM-------------------ARRPLSTIDP----DVLYVDDDPVITSAGTAAGIDACL-------------- +------------------------RTEAFELGVACEVFSLPVYDFSLVAGSPRPVTTR----FGY------------------TIDVPYDLD--RLDDADLIVIPAGGTGIADLDDLQPLFAKLRAAVDRGTRVASLCTGAFVLGAA-------GLLDDRRCTTHWRHAPRL-------------------AERPAAKVDP----DVLYVDDDPVFTSAGTAAGIDLCL-------------- +------------------------YVETFELGVACEVFSLPTYDFHLVAATSDPVRTR----FGY------------------TIEVPHRLD--LLDDADLILLPAVNSD----GRLEPLFAKLRAAVDRGARVASMCTGAFVLGAA-------GLLDRRRCTTHWMHADRL-------------------ARTPTAQVDR----DVLYVDDHPVLTAAGTAAGIDLCL-------------- +------------------------GVIPFELGIPARILTEDLYSVRTCAPRPGPVHTD----ADF------------------TIDVRYGLE--SLALADTVVVPSAHEAGPV-YLTRELRDALAA-IRPGTRMVSICTGSYVLAAA-------GLLDGRPATTHWKRTDHF-------------------QRLPRVRVDP----DVLFVDDGDVLTSAGVAAGVDLCL-------------- +------------------------DFATLDLGVPGQVFAGPLYEVVTCTPDGGPVRTR----AGY------------------SVVPDHDLG--VLATADTVVVPGIHG-GPP-ILDPRVRDALRE-AAGRSRLISICTGAFVLAAA-------GLLDGRPAATHWRNADRF-------------------RSLPRVRLDP----EVLFIDDGDLLTSAGVAAGIDLCL-------------- +------------------------RVEAFELGVACEVFRLPAYDFSVVTAIPGAVTTR----YGY------------------TVDAPHDLD--RIDDADLVIVPAGSDRVDAEFGLEPLYAKLRDAHARGAMIASVCSGAFVLGDA-------GLLDGRRCTTHWMHTAEL-------------------VERPAALVDP----DVLYVDDDRVLTSAGTAAGIDLCL-------------- +------------------------SFQPVCFG-AVAAFKETLYDVRVLSEEGGLVASG----AGM------------------QVMTDPFDD----AAYDTLIVAAGLE--I--PSSPGLVRLLRVAARDARRVAAICLGSFILGDA-------GLLNGRRATTHWRYAQTL-------------------QERPSCQVDM----DKIYVADGPIWTSAGMTAGTDLVV-------------- +------------------------DFDFMALA-VTSPFKATLYDVRVLAEQGGRVRAG----LGP------------------DIATEPLGAP---DAFDTILVAAGIG--L--PTTPGLAGYLRVAARATRRVAGLCLGAFVLADA-------GLLDGRRATTHWHFAAQF-------------------RERPAARLDI----DKIYIADDNIWTSAGMSAAIDLAV-------------- +------------------------DFDFMGLA-VTSPFREAAYDVHVLSERGGPIRAG----LGV------------------EVTSEPLADS---PPFDTLLVAAGIT--I--PTSPDFAARLRAAAGAARRVAGLCLGAFTLADA-------GLLDGRRATTHWHFAPQF-------------------RARPACHLDI----DKIYVVDGPFWTSAGMSAAIDLAV-------------- +------------------------NFDFMGLA-VTSPFRDTTYDIHVLSEAGGLLRSG----CGP------------------AVETEPLSEP---SAFDTIIVAAGIS--L--PPSPDLVAYLREAARSTRRLAGLCLGAFALADA-------GLLSGRRATTHWRYAPQF-------------------RARPDCQLDI----AKIFVADGNLWTSAGMSAGIDLAV-------------- +------------------------GFQVMNLA-PLTAFLRDFYEVTFLSEGGGPVRTS----IGM------------------VIETEPFSG----RRFDTLIVVGSVR--V--DSAPGLVERVRETAAGARRVAATCTGAFLLAEA-------GLLDGRKAATHWAHARDL-------------------QRRPSIKVDD----DRIFVADGNVWTSAGMTAGIDLTL-------------- +------------------------GFQILDMI-AVSIFQEPAYDVTVISEHGGMVRSS----SGV------------------EVATQPLGD----PAYDTVIVTGAME--I--ASSPGLLAFLNDALAASRRTASICTGAFVLAEA-------GILDGRHATTHWAHARDL-------------------QRRPRARVDE----DRIFIVDGSVWTSAGMTACIDLCL-------------- +------------------------GFQMMSLA-AVTAFADAAYTVNFLSETGGPVASS----IGA------------------AVETQPFGE----AHHDTVVVVGELS--A--GAPAGFIAGVQAASRRTRRIAGICTGAFPLAQA-------GLLDGRRATTHWAYARAL-------------------QRLPAVKVEE----DRIFIADGPVWTSAGMTAAIDLAL-------------- +------------------------DFDFMGLA-VTSPFWERLYDVRLLSEQGGRLRAG----LGA------------------DVATEPLAEP---DAFDTVLVAAGVG--I--PTAPGLAAYIRAAAQSTRRLAGLCLGAFILADA-------GLLDGRRATTHWYFAPQF-------------------RARPACKLDV----DKIYIADDNIWTSAGMSAALDLAI-------------- +------------------------GFQLADLAGPMTVFRPGAYALATREEGGGTVAAS----SGL------------------AVVAAPLGDPACDPACDTIIVVGGEGTTT--AASPAVLAFVRAAAATARRTTSVCSGSFVLAAA-------GLLDGRRATTHWRRAAAL-------------------ARHPKVTVEP----DRIFVRDGAIWTSAGITAGIDLAL-------------- +------------------------GYDVLDLGGPLSAFTHTPYDLHVVSQSGGPVLGN----TGL------------------SIETKP---I-GRRTFDTVIFVGGEI--E--PQTSENIAAARKLAAKASRVASVCTGAFLLAET-------GLLDGLRAATHWRYAALL-------------------QSRPRTRVDG----DSIYIVDGRVWTSAGIASGIDLAL-------------- +------------------------QFLLLDLAGPLAAFLRPLYSITVTSSDGGAVLSS----SGM------------------AMDTVP---S-NVITAETVMFIGGRL--E--PLEQSQISAATALSLGATRVTSVCTGTFLLAET-------GLLHGRRATTHWKAVPIF-------------------QARPSVKMQP----DLIYVSDGEAWTSGGVTAGIDLAL-------------- +------------------------GHQILDFAGPFGAFRRPLYALEVLSRAGGKVRGS----GGA------------------MVESRA---P-KGVALDTLIVVGGDI--A--PRAPGEVAAVRALAAKAARVASVCTGAFLLAEA-------GLLAGRRATTHWRVAHLL-------------------QREPAVRVEA----DRIFIADRDVWTSAGITAGIDLAL-------------- +------------------------GYDALDLGGPLSAFTHTPYALHVISPTGGPIPGN----TGL------------------SIDTKP---I-GRRAFDTVVFVGGDI--A--PQTSDNIAAAKKLAAKASRVASVCTGAFLLAET-------GSLDGLRAATHWRYAAQL-------------------QSCPRTRVDG----DSIYVVDGRVWTSAGIASGIDLAL-------------- +------------------------GHDALDLAGPLSAFTHKPYELRVVSHSGGSVIGN----SGL------------------PVETTP---V-CQHTFDTVIFVGGEV--E--PLTAENLAAARQLIVNASRVASVCTGAFLLAEI-------GLLNDRRATTHWNHTALL-------------------QSRPRIKVEG----DNIFIEDGHIWTSAGIASGVDLAL-------------- +------------------------GFQILDMA-ALTVFEHRHYDIAVVSAEGGMVSGS----SSV------------------KVEARAVGR----RHYDTLLIAGTTT--G--AREPELIAQLRRAAPRVRRLASICTGAFILAET-------GLLDGRHVTTHWALAHEL-------------------QQRPAVHVDE----DKIFVNDGPVWTSAGMTACIDLAL-------------- +------------------------GFQMISLA-AMSVFFTPLYEVLTVSVEGGLVKDS----AGI------------------SVATETIGR----RHYDTMLVAGATY--V--VTEPDLVDALKRFAPNVRRIGSICSGAFVLADA-------GLLEGRRATTHWGQASAL-------------------RQQPDVVVEE----DRIYVNDGSIWTSAGMTAGIDLAL-------------- +------------------------GFHILDLS-ILSVFHPGSYAVDIVSMSGGMVSSM----SGV------------------GVQTAAFGE----QRYDTVLVGSSPA--I--PPCPGLVERLQAAARSSRRIASICTGAFILGEA-------GVFDGRSVTTHWGFAEAL-------------------ARRPAANVVP----DKIFIRDGHIWSSAGMTACIDLVL-------------- +------------------------GFQALDLA-ALTVFGDVVYEFAALSVSGGLIESS----TGV------------------VVGTEAIGW----GSYDTLLIAGATS--I--PATPDLIDKIRHAAGATRRVASICTGAFILAQT-------GLLNGKRATTHWYFGRLL-------------------QEQPEIKVDE----DKIFVKDGDMWSSAGVTACIDLSL-------------- +------------------------DFQILDLA-ALTVFSKIQYQFASLSLDGGPVRSS----TGV------------------VIETQAIGF----GSYDTLIIAGALL--I--PAMPALEAKLKEAASDTKRIASICSGAFVLANS-------GLLDGKRATTHWAWGRDL-------------------QQQPAVLVDE----DKIYVKDGQVWTSAGATACIDLAL-------------- +------------------------GFQMLDLA-ALSVFLQPFYQFDIVSSQGGLIASS----AGV------------------KIDSQPIEQ----LEFDTLMVGGSTD--I--PVGPLLISQIQQAALATRRVSSICSGAFVLADA-------GLLDGHSATTHWGQAAAL-------------------QQRPKVRVDQ----DKIYINEGQIWTSAGMTACIDLAL-------------- +-----------------------------------------------------------------------------------------CLKDAKVADYDVLIIPGGHSA-DVMVTEPDVINFVEQAHATDVILATIGAGSMPLIRA-------GAMHGKRCTGDRAV---------------KFMLQ----K-IARFEE------VPVVVDGDLLTARSTADTPALLRALCAL--------- +------------------------GHPMLSVSAAIDVLALALYSWCTISQQD-MVQ--SMNGL--------------------NVQADYSLKDA-P-YLSTAIVCCGIDG-HQ-QATSEVLAWLRRVK--GTSVGAVSTGSWVLARA-------GLLEGRRCTIHWEDRAPFRE---TFP--------------DLNVT------EAIFETDGPVFTCSGGTAVVDLTLTFV----------- +------------------------SFSAFDLVSVIEPLKDARYTWHVLSEDG-ACR--ASNGM--------------------EVQVEGGLDAL-Q-KRDTLIVLGGDNF-QS-TATLRVMAWLRRQA--GLHLGAISGAVFALAKA-------GVLHGSEVSTHWTYRNMLRE---TFN--------------DLDVQ------RTIYQLGPNQFTCAGGLATLDLMLQLI----------- +------------------------QFSLFALACVSEPLRVALFEFSFISEDG-PVK--ASNNI--------------------AFNTQYSTANC-PDDYQTFIVVSG-FD-PL-VYSKSLLAELRRLA--GVSLGGVDTGAQILIKA-------RVMTGLRATMHWEAATSFQE---NNP--------------NADIL------QERFLIEDNRVSSAGGISGLDMMLSII----------- +------------------------HFSLMAFTAAMDALITALFQIQTFGIDSRKVL--SDIGI--------------------DIATDATVESLKRGSLDWLFVCGGYRC-ST-QASQPLTECLTSAN-QKINLGSIWNGTVALAHA-------NAIENTASAVHPNSHQFIHT---TFP--------------ALELS------SHTYEV-ANRASCAGPNSAMEMMLSII----------- +------------------------AFDMYTLANALEPLRLAVCQWQMLSLEGQQLN--ASNGI--------------------ATATT-RLD-QQ--TFDVLILCGGDNL-QL-DPDL--RQQLSHWA-QPISLGALGEAGWLLAQV-------GALEGVRCSLPEPGAALEFA---AFS--------------KLTPV------AAPFCV-RQRLTCVGPQAVQGLMHELL----------- +------------------------NFTLISLASAVEPLRMALYRWTTLSVDGGQVW--ASDGL--------------------QITPDAAMQK--APALDTVIVCGGVGI-QR-TVTREHVSWLQSQARQSRRLGAVCTGSWALACA-------GLLDGFDCSVHWECLASMQE---AFP--------------RVAMS------TRLFTLDRNRFTSSGGTAPLDMMLHLI----------- +------------------------GFSQLSLSSFLDPLRLAFFEWSVSTSNG-PVE--CACGL--------------------SVSADHAFSNISSARPHMVVLCAGE-RVEA-HASAPLINLLRLCR--RVPMAALGTATWLLAQG-------GMLNDAPCTIHWEKMPALTE---TFS--------------RLNVM------NNLFVRNDDLITCAGEFASFHLAMELV----------- +------------------------GFLLPDVAGPISAFEFAGYRIEAV---A--VR--S---I--------------------TINAA-DYR-D-L---DIVLLPG----R-DPA----ILPFIR-ES--RRRIIALSSGTYVLADA-------GVLEGRRVVTHWGLAAEFME---RFP--------------DVALV------ANLFLR-GHIWTCAGINAAIDVALAVI----------- +------------------------RFAMVALFSAIEPLRIALFRWTLISVDG-PVE--ASNGM--------------------PLAVNTSI--GSPLDVSSLMVCASFAP-LD-VVDERLLEWLHHQQ--NTALGAIDTGAFVLAEA-------GLLNQATTTLHWESLPEFRQ---RYP--------------HIEAV------ESLFEVTEAGFFGAGASASLDLALDTI----------- +------------------------GFSNLVFSCLLEPLRMVDVSWKVISADDAPVE--SSSHL--------------------LLTPTARRE-DE--ASDLLVIVSSNGY-RQ-HPTPENQRLVMTLA-QSRYVIGADAGAWMLAST-------GLLDDLTATLHWSVINEFAE---TFP--------------QVHVS------QQTYVK-GRLWSCGGASTALELILAFI----------- +------------------------GFSNMILACAMEPLRAALFSWQIATMDG-PVV--SSSRV--------------------SLSADLPADR--IG-TDALVVVTGYGA-RD-HMSRSVTQFIRKTS--LPLTVGLDTGAWLVAGA-------GLLTGRRATIHWMEVEAFAE---TFL--------------DVETR------TAPWEQDGNFVTCGGAGGVLDWALALI----------- +------------------------GFSNLVLASALEPLRAAEISWDICTIDGSPAT--SSSDL--------------------VITPKAALNAIT--HIDYLVVISGYDM-RH-HLSSRTRARLQNAA-HARTVIGVDTAAWLLASC-------NMLAGKSATIHWQELDQFRE---QFP--------------DVTVL------TDRFVE-GKMITSGGAATVMEMMLHIL----------- +------------------------DAQILDIAGPLEVFARTAYTIELV---A--VK--T---L--------------------AMQAGQSFA-S-F---DTLLVTG----S-NAM----ILRWLQ-AQ--CERLGSICTGALVLAAA-------GILDGHAATTHWEYLQLLAA---NTK--------------NCEVN------NVLFVQ-DNIFTSAGVTAGIDMALALV----------- +------------------------HSSILEVASTLDPMRNALFRWHVVSIDG-AVP--LTCGI--------------------ELPSQGPLPI--ALSADVLIVIAGFRQ-AE-VATRPLIQELRRIA--FLAIGGIDAGPWVLARA-------GLLNGYRATVHWEDLEDLAN---AHP--------------KIEVL------PDRFVIDKNRFTAGGAAPACDMMLHLI----------- +------------------------GFSMLTATLFLEALRFAAFDWKIKGVQSGSPR--ASNGF--------------------TLEAQSQIDGLA--PAEIVFLNVSYFP-EE-ARSDKLFNWLRSAR-HGAWILAVDTAPLLLAEA-------GLLMGKRATIHWDDLESARE---LFP--------------DVDFR------GSGIER-GRIFTCCGGMAVLDMTLEFL----------- +------------------------GCSLLTLASTVEPLRAAVFDWRFVSVDG-SPI--TSSGI--------------------AWPVSGKHDP--SSRCDVLAIIAGFGA-PQ-MTDRKLIAHIYRAA--ARLVIGIESGAWLLARA-------GLLDEHRAATHWEDFEEFAA---AFP--------------NVDLR------PDRYVIDRRFVTTSGASPTLDMMVDLV----------- +------------------------GVLLLDVAGPAEVLAEA-YALHYV---S--RQ--T---L--------------------PLQADPVR-----DA-DTLILPG----A-AAL----FMAWLR-KA--ARRTASVCSGAFFSGAL-------GLLDGREATTHWAAVEELRE---RHP--------------DTHVE------DALYVE-GKHWSSAGVLSGVDMSLAIV----------- +------------------------DSSIMSLASVLDPMRAAVFRWRLLSGDG-AVT--LTCDI--------------------PISVDGRFSL--PLAGDLLLVIGGFNL-ER-HVGKRFLAALQECA--FDIVAGIESGCWLLGRS-------GLLNGRKATAHWEELEDFSQ---TFP--------------ALTVI------GDRFVMDGKYWTSGGASPTFDMMLHLI----------- +------------------------ESNTLSFAAAVDPMRAAAFDWDYVTATS-PAM--LTSGL--------------------SVPGI-PLAR--LQSCELLIVIAGFQL-AR-HATPSLLAGLRRLA--GATIAGIDGGPWLMAEA-------GLLDGHPATTHWEDLDNFAS---RFP--------------GVQCR------NDRFTLSEGRMTSGGATPAIEMMLHII----------- +------------------------GFTMQAFSSAVEVVRLLGYRYNALSLSG-PVA--ASNGF--------------------RLIPDLAA--EAVPPRAVIVVVAGVRAGHS-AEPA-LAARLRGWA--GHPVWGISSGVVRLAQA-------GLLEGRRVAAHWEDVAYLRD---SHP--------------RVQVT------ASLFVSDGEVMTCAGGGAASDMMLTVL----------- +------------------------SFSNMVLACLLEPLRVVGICWKIATEADTEVS--SSSGI--------------------KVSPDTRLA-DG--PADLVFLISGDKF-RE-GNALIALRRYLSSL-QDCTIIAADTGAWKLAML-------GCLDGRSATLHWQLLDEFAE---TFP--------------KVRVL------SDRFVK-GRFWTCGSASAALDLILNYI----------- +------------------------AFSNMVLACLVEPLRVV-ITWNILTDNVP-VR--SSSGI--------------------ALTPDGP---VQANACDLLIVIGGDRF-RQDA---KYTTRKAMIA-KAKAVIAADTGAWLLASV-------GYL-NKQATLHWQLLDEFTN---TFP--------------KVNSA------TPF-TSDGKWMTCGSAAGAMELVLQEI----------- +------------------------RFSNNCLANAIEPFRAALYNWQFVTLDG-PIE--SSSSL--------------------KIVPDAPLSR--VG-GYAVVVLSSYGF-QN-HGTPACLAALRAAA--HEVMIAMDAGSWLLASA-------GLLNNRLATIHWEEYDRFAE---QFP--------------DISTL------RERYVIDGDRITCTGAMAAYDLASHLV----------- +------------------------RFSNHCMANCLEPFRAAVYEWNFVTLDGLSVQ--SSSEL--------------------RLMPDQKFG-EK--RADFLFIIASYDF-RR-HDSVASRRALRAAM-RYKNIIGLDSGPWMMAGA-------GIIDNHRATAHWDIIDEFSE---EFV--------------EVNVE------RQKYIF-GNIGTCGGGMAAFDLSLSII----------- +------------------------GFSNLCLANAVEPLRAAHYRWRFVAMED-PLQ--SSSGL--------------------PVQPEPF-DR--DA-GDMMLVMPSYNH-VA-LATPDTLRRLRGAA--FGLVAGLDSGSWMLARA-------GVLNGYRATSHWDILNSLSE---EFP--------------EVDVV------ADRFVIDRNRASCGGATATLDLMLELI----------- +------------------------GCHPAILMPALAVLRSALYLIDCFTLDD-PIL--SPEGW--------------------QLPARRWEG-AE--ALSHLWLVADERL-PV-SMSPTMVLQLRSLAREGVHLGGLEEGVFPLAMA-------GLLDGHRCAVHWRMLEEFRE---RFP--------------AVQAG------TRLFEQDEGRLSS-SGCAITDLFLTLV----------- +------------------------PISFGALGAIVDPYTEAYYRIRLASVDGEPVT--LASGA--------------------SLAVSAALPS--ITGCNALVVAS-DAH-RP-G-EDGILASLRRLSLSGIAFCSNRGGTGWLASA-------GLLENRRVAVHWEEMGVYRD---RHP--------------GLLHC------ATLYEVDADRLTASSNLAMLEMMLFVI----------- +------------------------EAEALSWSALVQPLRLAGLQLDVCSLAE---------------------------------AAQPLPEQ--HPGW-LALLVG-EEG-AR-D-DPGLCRAAIER-CQAAYWGAVGAGVLWLAEA-------GVVGGVRIALPWALYADTED---VPS--------------RAVLI------PQLYVIDGRHLSCCGGAASLDFSLTLI----------- +------------------------PCSLLTLGAITESLACIKYTLFYIAT-DQPVT--MAAGL--------------------TLHAEQAISDAD---CQLLIVLASHAP-QAALSDDVKRALAVYAA-GDSHLLALDNGGLWLLES-------GIGLDATWAWHGHTLDAAAQ---RYP--------------QLALS------HELYVI-ERLSSGCGQSAALDCLLAYL----------- +------------------------PVSMSGVGPVVDALNLALYRWQVCSWDGRPVP--LSGGA--------------------QWPADTAFGD--AISCDWLILVS-ERF-QQ-F-YRMFLASLSRVGQRTPLVTGIHHGVWWLAMA-------GQLSGYRVSVNWETYQQFTE---QFE--------------RSIVT------QQIFEIDHDRATCAGGQATVDFMLAMI----------- +------------------------HFSLTALSTAMDALATGVYKVSTYSLQGGLIE--SDIGI--------------------PLPSERLNVE--KINHEVVVVVGGQRV-RL-STNPAIRRVLKKTA-GKGIVAGVWNAAFYLVDA-------GLLDDQHCACHADSCALINE---YYP--------------QVKTV------AAQYTFSQRRATCAGASSALDMILAIM----------- +------------------------GFSALELGSGIDSLSAAFFHWKTVSETG-SIV--SSSGL--------------------NVAVDGPL--PDIQRGDCIVVCCAFNSQNY-RKSGKTVAWLRRAA--GIRLCALGGGSLFLARI-------GIVTEGRISTHWRMKPAFDE---GYL--------------DLEPS------CTIFEENANIVSCGGGAATLDLFSALI----------- +------------------------GTASLDTSLTIQALKTAAFHWRIATMDG-AID--LEDGF--------------------ILQPDMAVGDDA----IDLALVFGEWGVRT-GKSNYFVNWLKRLD--SVYVGAVGGACYELASA-------GLLNGYQCAVPWAYHDSFKE---LYP--------------TVEIQ------DALFSWDRKRITCTGKAACLDLILNII----------- +------------------------GFVATELAIAFDSFRIALFRLQIVSVDANTLT--SLGGM--------------------EITVTPMDS-T-TNLPDLLIVTGGSEM-AR-AL-RRFLPRLQRVR-AGGLAVVLSDAAQALLTA-------GA--AETAAVHWEGRPMLEE---AGI--------------AERGT------NTLFNR-GNLVTSAGMAATADVVLALI----------- +------------------------THSPADVSLAIETLSEAPYTWQILSEDG-PLR--SQSGL--------------------SLAVEGGVEEID--LTATIFLCGGNRM-EA-PASQKLLNLLRKAT--GATLGALGSGCAILAQA-------GLLPDKKVAAHWAISTSIQE---TFP--------------DLDVR------QQVYDTSSKSLTCAGGLATADMFLNVI----------- +------------------------GFSLLSLTSLTDVLDAVSAKVSLLTPDGAPVR--SRSKV--------------------LVAPDTALPDRPLSKPDVYVICSGARL-AD-RDAASVLELVRQCR-NATPVCVMGGAIRLIAKS-------GH--ITRGTDHWSRIPAGRE---ALP--------------HIEFE------DSIFVR-GNLYSCSGELGAMDFALNWV----------- +------------------------EPSVHSTFVAVEPFRAAAFTIDFIAADPKSPP--ESMNF--------------------AIPLTAAFE-SR--KYDLVMLLATYGI-DE-QAKPRLFKWLRRQS-AGAHLSGIDTGPLLLAEA-------GLLKGYAATCHWTAMASLRE---LCP--------------EGTV-------EQIYVV-RNRSTCAGQAATLDFSMTLL----------- +------------------------TFSVLALSAFVDTLRHARQGWQICGDRSP-IR--ASAGI--------------------DVTPDTTFT-EM-QDPDYLIAIGALMP-TID--PQETLDYMRAFH-RGGTVIGLCTGSFILGQA-------GLL-GRKAVVHHRHRRDFLS---RYP--------------DVQIS------RDIHVRDGRVITCPGGTASIDLAISLL----------- +------------------------KLTMLAFSAAVEPLRIALYRWFLISQDG-PVP--CSNGI--------------------GINTDMTLED--LPRGSFAFVCSGIEP-SD-SASPKALSWIRRQN--GSRFGGICTGAFALAQA-------GILQEQRFTLHWENQPSFSE---YFP--------------GLEPT------ANLYEIDNGLMTCGGGNAATDMMLEMI----------- +------------------------QFTMLAFTSALEPLRVALFRWNVYSATG-AVP--SSNGV--------------------AVMPDAALPPE-P-PEGYILVCGGVEP-DR-NTGPEIASWLRLAW--GRTVGGLCTGAYALARA-------GILSGRKFTLHWENIPGFAE---TFP--------------DLAPV------RQLYCIDGRIVTCAGGVAAADLALKII----------- +------------------------GFTLLAFSSAVEPLRIALYQWRLLSEEG-AVA--SSSGI--------------------SVCSEGALAPL-P-RDTRLFVCSGNPA-SA-AAAPPVVAMVNRHA--GGTVGGICTGAVALAQA-------GLLQGVPFTLHWENQPAFCE---AFP--------------DLTPS------PAMFEIAPRVMTCGGGAASTDMMIALI----------- +------------------------HFSLLAFTQALDALVTAAFSHSTCSLDSAALT--SDLAI--------------------LIGPSASLSE------DLLVICGGLRT-PL-TLPEDLATSLQELA-RKVALAGLWNGAWFLGRA-------GLLDGYRCAVHPEHRAALAE---LAR--------------HGQVS------SEAYCIDRDRLSAASPAGALSMMLEWI----------- +------------------------HFSMMAFTGAVDALVTAVFEVLVVGGESNLVV--SDLGI--------------------AISADCSLAEME-RHLDILVVCGGYRV-RL-QGDPQLRAKLRQAD-SGAVLGGLWNGAYFLAEA-------GLLDGHECAFHPDGRAMMAE---LFP--------------KVRVT------THSHVLDRKRLSCAGANSSLGMMLEVV----------- +------------------------HFSMSSFSVVLDTLVTLIYECKTYGVNSNKAL--SDVSI--------------------EITTDGNIRDIK---ESILVICGGFRN-SL-RPEPLLNKILVKAA-SHTTIIGIWNGSFYIADS-------QIKTGGTLSIHQDNKAIMEE---RFP--------------TLNLS------TSSFTEDGLLFTCCGPNTALDMMLHFI----------- +------------------------DYSMIAFANAVETLRMALYRWSVVSPDQ-VAL--ASNGL--------------------AVAAIGDLGS--LSECQQLFVCGGVDI-RH-NTSDTVRRLLRQCA--GVPMGGLCTGAYALASA-------GLLDGYRCAIHWENLAAIRE---EFP--------------KVRFS------SEVFVIDRDRITCSGGTAPLHLMLHLV----------- +------------------------EFSLLGAVCASETLRVAPFRSVFVHDTQ-QVA--SSSGI--------------------PLQAEMHVRDLK--EFDALVVLSSFRH-DS-YENAETLSLIRRFD--GKMIGSIESGVYHIAKA-------GVLNGHMATAHFNNLPMFAA---LFP--------------KVSFV------KKVYTWSEKRMTCAGGAAATDMMLHLV----------- +------------------------EFSLTTLTIATEALRIALFDWQIVSEDGGNVR--ASSGL--------------------WFAADCDLA-SE--IADVTLLFEGNLP-TQ-HLSKHLLGYLRRAA-FGSVVGGLDSAAYALSQT-------GLVGTETSVLHWEAVPSFRE---WFP--------------DARPL------NRIFQL-QNRAQCAGGIATLDLMLELI----------- +------------------------LFPMYVVVLATEALRLAVFDWQILSEDG-AVE--ASNGI--------------------AVDCDAAL--RDAPELAYGFIVAGDDQART-ATPQ-MRRWLVRAG--GTVLGAIDSGVFLLAEA-------RLIRERNVTVHPVAAAAFRE---QFP--------------EVNVQ------ERPIVVDGSLITCAGGMATVELLLMLI----------- +------------------------QFGLLGLGAVMEVLYQFQLTWEIVTADK-AVT--ASSGA--------------------AIQPGCTI-DA-DVNYHSIIVFGAQGA-WE-YSDNRVFNWLRFHA--GTRFGTVMSGAWVLAKA-------GLLNGFRCSVHWQDIEAFKE---VYP--------------LVKIS------SDIYSIDDQRFSCSGGHVASDMTLHLL----------- +------------------------DFSMLSVVTAIEPLRVARYLWRVLYETG-APM--ASNGL--------------------SLNDC-----RAT-DPDYTFVCAGMHT-KV-RDPGRLSATLNRRF--GGVVGAVSLAPTLLARA-------GLLDGRRSVIHWEGLAAFTE---EFP--------------EIEIS------NGLFEIDGKIMTSCGGLATLDLFLEIL----------- +------------------------EYSMMSLLSITEPLRIAVFRWQCLSENG-PVI--ASNDM--------------------ALEQSIHVDF--CPSPKNVFVNASFRP-EK-YISETCIKWLRNLD--KSVIGAIDTGCYALAKA-------KLLDGYKVTLHWEAKPAFQE---RYP--------------YLNVS------DELFKIDGNRITCAGGIAASDMVLYFI----------- +------------------------DFSLFGLTSMLGPLRHALYEWELVSEFG-LIR--SSDGI--------------------DIMTNVSIKEV-E-QCETLILCSGCHD-PQ-TVSPAVLGFIRQSY--GADIGCQDMGAYLAAAA-------GILDGHRATVHWENHESTQE---LFP--------------NVEFV------QELLVIDRKVFSCPGGLSGLDMMLYLI----------- +------------------------GVHLLDISGPAEAKEYD----FFVSNKNR-TS--SSAGL--------------------NFYDLLP---NELTNEDFIFIPGSLLD-TN-FDCKPFFEWLNVQN-KGVNICSICNATFLLAES-------GIL-NKSCTTHWKRIAKFKE---RYP--------------KIEID------NRLFVIDGNIFTSAGITSGIDLALYIL----------- +------------------------NFTLLALSCIVDTLRLAAYRWTVYGLHE-VA---ASSHV--------------------SILPDETLAGADG-EVDIAIVCGGIGG-HL-YNR-PLRAWLRDLD--GAIIGAISTGIWQLARA-------GLLDSYRCAVHWDDLPSFSA---TFP--------------LVEVR------SEIFVHDRRRLTCSGGVAVVDMILYLV----------- +------------------------GYSSISYVSAVEALLVCYYRIENACLTGNSSV--SSLGN--------------------KVTCEHCLDT--LGPMAYFIA--GTSP-GT-Y-EEILHTWLAEL--PDSVLAGIATGSYDLARA-------GLLNGYRAVIHWWKYEEIMS---SFK--------------SVVLS------TDVYAVDRNRYTCRGGTASLDMMLFLL----------- +------------------------GYSSMTYVSAMEPLLMCVFQTFTVALAGRKTV--SSLGN--------------------AIDTNYSLDD--APKAVWIIA--GTTP-AR-H-APELDAFLLAR--GTAALGGLASGSYTLAHL-------GLLNGYRGVVHWLSYDELLQ---KHK--------------SILLA------SEQFCIDRDRLTCRGGSSSLDLMLMWI----------- +------------------------DFSMISLAAVVDPLRMALYSWDFYCHQN-TVF--ASNGL--------------------PVAPTRQQDD--VTDLDTLFVVAGIGA-QE-ANDAALFSWLRGLK--KVNLGSTSTGSLLLAQA-------GILKQQKCTIHWENKESLSE---QFP--------------DLQVT------GELYEIDRDVMTCSGGLAGLDLMLQLI----------- +------------------------SGVAYAAEACIDVLRSAAYGWTHLR-----------DDH--------------------ACDAAPI---CPD---QTLVLIGGTEH-PWRPK--SHLTALRACI-NAARVCVVGSAVFVPLAA-------GVL-TKRLAVHPNFRPGVEE---TGR--------------GLDLQ------GAT-CHHNALSSAISPAAAMRMIVELV----------- +------------------------GFSMLSTITVLETMRIAVFAWSTASEDG-PVR--SSLDM--------------------AFPVDGPLGNP-R-SGSIILVCGGTDV-QA-TASRQTMAWLRKCI--GVFVGGLCTGSYVLAKA-------GLLQGRRVTIHWEQSDSFAE---NFP--------------DVDLS------TAPYEIDGGTLSTAGGTAGIDLFLEVL----------- +------------------------NFPLMAFSAIIEPLRAACYSWVTVSPGQDRIH--ASNGI--------------------CIEPDFAACD--APTVDRIVVCSGGNA-DH-LVAGDETAWIRRNL-AGARLGAVADAAFFLARR-------GLLDGHACTLHWTSQPAFRE---TFP--------------GLDMR------PDLYVIDQNRFTSAGGVGSLDMMIEII----------- +------------------------QFSMMALAGASEPLRVALYEWTLLTESG-PVC--SSSGI--------------------EIH-TVAIDQ--APAVDRVFVLASLDI-ER-QKPPKMLRYLQRAA--GVTVGALSTGTFILARA-------GLLDGKRCTLHWETIGQFCE---EFP--------------TLEVT------KELYVNHDNRWTCAGGTAAIDLMLAQI----------- +------------------------QYSMMAFFAAVEPLRIALFDWTLISADG-PVT--ASNGM--------------------TLMVDHATADV--HHLPSLAVCSGFTP-EA-HLTRPLMAWLHQLD--GCCLGGIDTGAFLLAAT-------GLLKHERVALHWESLPAFRE---RFP--------------GIDTT------DELYELGERRFSCAGGAAAMDMALEVI----------- +------------------------NFSMIAFSNMVEVLRMALYQWNVTGLDGHHSC--ASNGL--------------------QIQHTCVWSH--LLNMDIVFICGGFQL-YK-NMTVRLKNFLYRLD-QKIALGGLCTGAYVLAKA-------NLLNGFRASLHWENTLAAQE---EFP--------------LVQFT------PHIFTIDANRFTCSGGLAAIDLGLALV----------- +------------------------GFSHLSLVSALETLQAALYDWKTCSLSG-PVR--SSVGL--------------------ALPVDFDV--RDIAHPQDIVIVSGEGA-FE-IDIGRLKVWLARVG--QTRVTAIGTGSIIMARI-------GLLDGKSAAVH----PWYRT---GFT--------------ELYPS------VTLSRQKGLRCSASGGVSGIDLFLDLV----------- +------------------------GFSVLGLAALIEPLRLALFAWRTLSPDG-PVV--ASSGF--------------------AVGVDGTG--DPDAAFDGLVLCAGGEVE---APDGPYTELIAASA--GALVAGIDGGAEGLAAA-------GHLADRPVPVHWRRREHFAL---CRP--------------DLAAS------DGLFDLSDTRASSAGGMAVVDLALALI----------- +------------------------GLSMLSLASATEPLRAAVFRWDLCSIDG-PVM--PSSGI--------------------PFPAIHVDQA--IERNHALFICGGARV-DP-QDERPYLAALRRAA--GRAIGALSTASYLLARA-------GLLDGYRCTIHWENRAAFEE---DFP--------------HLPIT------GTLYEIDRNRLTCSGGTASMDLMLHII----------- +------------------------GFSHLSLALMLETLKQALYSYVLVFDDSHLLY--QDETVK------------------PLSVLALSLA-QE--GFDLIVVLGGNQH-QQQMSQGP-DAFIRHHY-KGAWLVALQTGVHRLASL-------DLLNNKPVSCHANYLKDLSE---QYP--------------RLSFN------THIFSF-QGIYTCAGGLATADMMLDLI----------- +------------------------GFSLMAFTSLTTPLRIAAYSWNIVSHDG-PVR--SSCGV--------------------SLSAECDLDCAAIDHARFLALLPGDKH--E-VFPARLISWVREAV--GVSVAGVGRGALVLAEH-------GLLDGRRCAVHWSVFAPSIE---NFP--------------QVVFS------RAYYEIDGLIHTCAGEAAAFDLVLEII----------- +------------------------GFSLLAFTSLTAPLRIAAYSWDIVGQLG-SVR--TSCGL--------------------CLPVDCDIEAAPYDRTRFLVLLPGDRR--G-PFPARLISWAREAL--GVSVAGIGRGALMLAEH-------GFLDGRRCAVHWSVFGLSVE---NFP--------------DVVFS------RAFYEIDGLLHTCAGEAASFDLMLEII----------- +------------------------GFSMLCFSSALEPLRAAIYEWKLYSIHG-TVR--ASNGM--------------------DINVDAEIAL--DDNIPVLIICASYDV-EE-SNTKQLAAILRRLR--GTEFGGMDAGSEILAKA-------GLLDGYKATVHWENFESFTE---TYP--------------NIQAE------LDLYIVDRNRFTSGGGTTSLDMMLQLI----------- +------------------------RFSMIAFTSVVEPLRLAFYRWRTYSLDG-AVT--ASNGC--------------------EISVNHSIRE--LEDADITLLCSGIDV-ER-LPLDKELGTLRKLN--GRTFGAICTGAYLLARY-------GLLEGRRCTLHWENLRSFRE---EFP--------------GVDVS------SDIFAIDRNCITCGGGMASLDMMLRLI----------- +------------------------DFPLMTFAAALDSLRQGAFEWLILSADG-HVK--SSSGL--------------------GFDADAAIGRA-P-RCDIVILCAGINY-AD-AYDANVFAWLRRIH--GCVLGAVSTAVFFLAKA-------RLLEGRRCAVHWESLASFRS---EFP--------------NCLAT------DDIFAIDGRFLTSSGGTVTLDMMLYLI----------- +------------------------GFPIEEYALFAAALHDA-LKIDVLSNGGF-VR--GSCSA--------------------AVQTRPL---TLLDGLDYLVVFGGHKA-APGSQ--RFRAALQTLR-NGCQIAAVGGAALTLAKA-------GIF-SYSCAVHWQNRELFSG---LMS--------------VVDPD------QVC-SVTEGDWSSCGKTGTLDLALHVV----------- +------------------------RHSLLASGAAAEALVAARYAPLMLSLDGQPVT--AACGT--------------------RVMVQGSLAM--APPLRAALVVS-ETL-PG-ADALLLARWLREQAAAGALLGGLGTGAAWLAAA-------GLLQGYRATVHHAQVAQVSE---LHP--------------QAVFS------SNVYEIDRDRLSCGHGTASLDLLIAWL----------- +------------------------GFALLSYASVIEPFRAALYRWAHISVDG-PVS--ASNGA--------------------MVVADAKVGAA--TACDMLLVFAGGDP-SL-FRDAATFGWLRRLA--GVAIAGVSGGPYLLARA-------GLLDGYRATIHWEHAAAFRD---AFP--------------DVALD------TGLYVVDRKRMTCAGGTAGLDLALDLI----------- +------------------------KASMLAFTSAVEPLRIIIARWRLVTPDG-PLT--FSSGL--------------------SMMAESPPRDLH----TRLIVCSGT-EPET-SLSDAVTAMVRRAW--GHIVGGICTGAYTLAEA-------GLLLGRRFTLHWENTDSFEL---RYP--------------KLLST------RQLFAIDNNVMTCAGGTAATDMMLSVL----------- +------------------------GFSLLSLTSLIDVLDAVCVDVTILTLDGTPVR--ARSKV--------------------QIASDGSLLDNLLPRPDVYAVCSGPQM-SA-AETALTLELVRKCR-SSTPVCAMGAAVRVIAQS-------GL--ITKGTDHWSRIPANRE---TLP--------------HIDFE------DSIFVK-GNLISCSGELGAMDFALNWV----------- +------------------------GFSILAFSLVVGALHAAIYRWSVSSVEG-PVV--SDSGI--------------------CLPTDDMGVMDPETGQNLVLICDGGFA--Q-ETRRRIANWSRRVA--GGRVVAIGDASQLLAEA-------GLLAGRRCAAHWRDYAVMAE---KYP--------------SVQIT------RHYFEVDGPFYTSPGEMATFDLMLRMV----------- +------------------------EFTMLAFSSALESLRLAAYDWRLVSSDG-PVK--ASCGI--------------------SIATDISLTQANGAPPRMAMVCAGRNV-QN-HCDRELLGWLRECR--RVAIGAICTGAHLLART-------GLLNNKRCTIHWENYSSFAE---EFP--------------TAELS------SHIFEIDDGIYTCAGGTTPLEMMLELI----------- +------------------------NFSHLSLTTALEALRQAQFSWALCGEGG-SKQ--SSLGF--------------------SAALDMGLEDL-R-PGDTLVVVGGVEV-DA-GSTDAVLAYLRRMA--GLPVGGLCTAAHTLAKA-------GLMDDRRATIHWENSESFAE---IFD--------------TVPLC------DEFYVLEDGYFTTAGGTTAIDLMLALF----------- +------------------------QFTSIALFSVVEALRVAPYGWTLTSLDG-PVP--DINGI--------------------PVAVNSRFGEM-DLREGTVLIAGGDAP-ED-HCTPELCSRMRWLA--GVKLGGIDTGQQILAEA-------NLLTGRHVTIHWENAPSFCE---HYP--------------MLEIS------QNLYEFDGDRVTCAGGTAGIDMVLHAV----------- +------------------------QFSNLGLALVIEPMAIALYEWTVLSIDG-PVQ--ATNGM--------------------IAPARPVS--GETGEFSTIFVIASFEP-KK-HANRKVKAWLRRES--GAQIGGIETGTEMLAAA-------SLLDGRPAAVHWDNLEGFQE---AYP--------------NVKAT------TQLYTIEPRLITCAGGSGIIDMMLEWI----------- +------------------------NFSLLSFASAIEPLRIASFNYRCCTVDG-DAI--ASNGS--------------------VMRADCALEEI-A-RADLVAVCSSDDV-ER-VETARQKALIRQLA--VNRVAGICTGAYVLADL-------GLLDGRACTIHWEYADLFRE---MFP--------------RTDLV------DNLIQADGRFLTCAGGTAAIDLMVGFI----------- +------------------------ETNLILVASVIEPMRAALYSWTLYSPDGEPIE--TKSGI--------------------PIPVAGAFRP--QRETAPLFILSSYNW-QR-SATSQLKMMLSQTA-HRELMAGIESGSWLLAET-------SLLDNSKATTHWEDFEDFTA---TYP--------------QVTMV------RERFVIDGKRITTGGSLPTLDLMLELI----------- +------------------------QFSLLTLSAAWEGFRLATYVCQTVGVTG-EVR--SSNDI--------------------IVKTDKEVADD-P-SFDITFVISSLNS-AE-FRQ-RLEVWLQAQA--GKLLAPIGSAAVLLARI-------GLLNGYRCVTHWKHHEQFLE---RFP--------------RVRLS------RGLYCVDRERLTAAGGLSALDLGLSII----------- +------------------------GFSLISFGAVVDPLRLALYQCVTLTLNG-SVR--SSAGV--------------------CITPDCAADDA-M-ELDAILVLGPNPL-PT-TGE-PIVRWLRAQA--GVALGGVDTGSYFLACA-------GLLDGYRSTIHWEDMDSLLD---RFP--------------RLVVS------SKLYEVDRNRCSCSGGIAPVEMMIHLI----------- +------------------------DYALMSAASAVEPLRAALYDLQFVSIEG-FMP--SSVAG--------------------GFETIALAEAD--ENLDILFVVAGGDP-LA-QRDPRVLAFVRRLA--GVALGGISGGAAILAAA-------GVMAARRFTIHWQHLDAMRE---TWP--------------DALIE------RRLFVIDRDRFTCAGGMAPLDMMHALI----------- +------------------------AFSLYAFSSAIEVLTLAAYSCQVVSGDG-PVT--SSCGI--------------------TISPAVGLRSERSTPAPIAIVCGGRSL-PR--NDSKLEAWLRECR--RARLVGIGGGTFVLARA-------GVAEGRRCAVHWEQFPLFQE---QFL--------------SVIAT------QAAFERDGDLYTCSGGDASFDTFLDLV----------- +------------------------NFNLGATMAFLDPFRAARFRWVLASPAG-SCL--ASNGI--------------------TVQTERLD-AVQEDVFEIVVVSASWTP-ET-ASTPHLLALLRKWA--GSIVGGLDTGAFILADA-------GLLDDRRATVHYEHIDSLKE---LHP--------------EVEVS------EDIFVHDGKRFTCSGGIASADIALHLI----------- +------------------------NFSLISFTSVIDSLVTANFSFFTCGINKSSVM--SDVGI--------------------SITVDVTLRPDL-KQAEMIIVCGGYRS-PL-NEIPLLSRALRAVN-KKQRLGGLWNGALALCHA-------GILSSQTFALHPDNHAYARE---HFP--------------HINLT------SQTYVIDGHFFSSSGPTSSLEMMLNLI----------- +------------------------RFNITTLITMIETMRIALFSWDIVSFDG-EIV--ASNGM--------------------TTRVSTQH-DT-LPTADHIFVLGSWGT-EH-YDNRLLTAWLRKRA--GSGICGVELGCYVVARA-------GLLERKPATIHWSWLSGFRE---SFG--------------RVDVQ------ECLFTIDGKIMTCSGGLAGVDLMLRLI----------- +------------------------GFSMLSLAAIIEPFNQAHFRWRLVGVLR-SAV--ASCGI--------------------EVELSDDLTSFSALQEHLVVVCSGN-DVDR-HVSSKTRSFLRGMA--GATLVGVGTGAWMIADA-------DLLEEKECTIHWSKMPSFSE---RFR--------------DITVN------GQRLHSDENIYTCAGEMASFDFSLDII----------- +------------------------GFSHLALHAYIEPLRIALFRWQVVGIDS-AVV--GANGL--------------------SISVGATIEALERAGPNQLVIVAGE-PVER-QSTPGLNGFLRTIA--GVAISAIGTATWLLAQA-------GLLAECRCTIHWSRLAAFSE---VFC--------------KPRIR------DSLFVKDGQYSTCAGELAAFDLAVDLV----------- +------------------------GFALTSFSLAIEALSVAVYQYQICHVNN-SVS--SSNHV--------------------PIETSGDLN---CQNSDLIFVCGYLNT-AD-YDNPALFSLLRRVA-KKGRIAALSCASFILAKA-------GLLQGKSCTLVPEYKTTFTE---LYP--------------DIPIQ------ENLYTVTDNLLTSAGGTATLDMLLYLI----------- +------------------------GFDLLALAVALEPLRQASFGWTLLSVDG-SIR--AGNGL--------------------CVNAEAPL--LARPPADLLVLCGPDGCRAN-ATEG-------------------------------------------------------------P--------------D----------------------------SASALLQLI----------- +------------------------QFTFLSFAAAIEPLRIALYRWTLMTE-GGGVR--CSNGS--------------------RLVADRALD-D-VARDDVVMICGGLDV-RA-NTTPGLLNWLRRTS-RGSVIGGLCTGAHVLAKA-------GLLDGRRATIHWENRDGFLE---EFA--------------EVDLT------KTVFTIDGNRLTAAGGTASIDLVLTLI----------- +------------------------KVNLYHYAIISSLLSTKLFSL-LR---F--VT--T---V--------------------QITALTDWK-E-I---DAIVVPS----D--VP----LQELIR-SF--NKWLIGACFGAYALAYS-------GVLNGKNCCTHWSAEEDFSK---EFP--------------YCSLK------NVIYVQ-DNILTSAGASATVDCILHFI----------- +------------------------HFPILGFVLIREVLDMALFSCRIRTVTGQTVA--ASDGT--------------------NIAAEADWE-GQ--GFDLVVLCAGPHP-LD-HLPMGLRGFLARAE-AGATLAGLDQGALILARL-------GLLDGREAVL----PPDPDR---TYP--------------EVAQS------ERRHTF-RQRLTSTGGLATAEAMLDWI----------- +------------------------GYVPTELALVLDVLRIARFAHQVCTDDAL-VE--GMGGS--------------------LVRATPF---QDGALPDHLLVLGGAGI-RPAF---RLKPRLCWLE-LGVSITLLSDAAAEW-KR-------LHP-TDDMTTHWEIQQLDQD---AGY--------------SLDQL------PLF-AQKVRIMTGGGMASTADLVLSQI----------- +------------------------EFPSNSLVLIQEALRITIFKSKLISNKKK-VR--SSNGQ--------------------WWKVDGG---LDIHNPDFIIVIGGNLP-VQIKK--KLFSILRTAH-NLSKIIAVDTGAFLIAES-------GLINETVVCTHWETKSNFID---RYP--------------HVRID------NIYTINPNGLMFAAGGVSTLDLILECV----------- +------------------------EFPSNSLVLIQEALRITIFKNKLITDGKK-IR--SSNGQ--------------------WWKADGG---LTIKNPDFIIVIGGNLP-LQKKQ--KLFSTLRIAH-NLSKIIAVDTAAFLIAES-------GLINETIVCTHWETKSNFIE---RYP--------------NIKIE------NIYTINANGLMFAAGGISTLDLILECI----------- +------------------------SLRTFEFGCAVEIFGLEWYQFKVC---G--VQ--A---V--------------------SVTFEYGSE-I-LDQ-DTIILPG----N-E-A----LVNALR-RA--GARICSICTGAFVLAAA-------GLLNGRAVTTHWHHSNLLSQ---RYP--------------SLRVS------SSLYIE-DNIVTSAGSAAGLDMMLYIV----------- +------------------------IQPTFELDCAFEIFGLPRYDFTIC---T--IP--T---Y--------------------TIHVERGLE-A-LDS-DTVIIPG----T-A-P----IKTSLI-DA--GARIASICSGVFALAQT-------GLLDGRTATTHPSRIDELHR---AFP--------------SIDV-------ETRYVD-SDVATSAGATTGIDLCLCLV----------- +------------------------GLNILDVAGPVQVFSSARYRLRFV---S--VT--S---L--------------------RLQADVVA----ST--RDLLIPG----D-HAM----ILDFLAWPS--DRRVISICSGALVLANA-------GLLNGRKATTHWRRARQVQQ---QFP--------------QVRWT------DELYHI-GKVMTSAGVASGIDLALEII----------- +------------------------GVNILDVAGPIQAFKTALYSLSFV---S--RE--A---L--------------------RLETDHIC----ED--DDLIVPG----D-AAM----IQHLVKWIA--GRRVISVCSGALILANA-------GVLNGKSATTHWRRSELVVR---KFP--------------DVNWV------NEIYRI-GDIYTSAGVTSGIDLALEII----------- +------------------------GFSNMVLSHAMEPLRAAAFDWWTCTLDG-VAT--SSSGL--------------------RVAVDGALAD--LPRTDLLAIVAGYDF-DA-LAGPDLLAQLRQVS--VARIMGCDTGAWVLAEA-------GMLSGRRATIHWHETDRFAE---TFP--------------DIDVL------TRDFVVEGDHITTGSAEGTLAVMLELV----------- +------------------------GAKPLDVGIPAQVFSTRPYEVRVC---G-------GDGL--------------------SYGVAHGLE-A-LEW-ETVFLPG---DR-ED-----VVDALR-AA--GARLAAISTGAFALAAT-------GLLEGRRATTHWHYTRALAE---RHP--------------GVRVE------NVLFVD-GTVLTSAGAASGIDLCLHIL----------- +------------------------GVPAHQLSTPGLLFGAAPYELRVC---A--RA--G---M--------------------TVTADHGLD-G-L---ATVIVTG----P--AP----VLDALR-AA--GSRLAAIGTGTFALAAA-------GLLDGRRATTAWSHAPELAR---RHP--------------RIEVL------GDWPVA-GPFLTSSGVLGGKDLCVRII----------- +------------------------R------------SAFGIF--NYVL---A-ET--YRI-L--------------------KNGIFQIE--LSKDKYDYVIVSPSQGM-HEDMLWHKEGELIKSLH-NNVVIASACLGVLFLASI-------GIL-GKQATTHWASESFVKK---NFP--------------KVQWM------QKMLCETPSVITAGGYLAVVDLTLNII----------- +------------------------GMNMLDIAGPSEVFTEAEYGITYV---T--VR--A---L--------------------NMSADGGA--F-DD--DTVFIPG----P-KGP----LVRATR-FL--AGRLASVCTGAFLLGSA-------GLLDGRKVTTHWRHASELAR---RFP--------------MAHVP------DRIFVH-RDLYTSAGVSTGIDLALSLV----------- +------------------------V------------NVAGFL--TYLNQGKP-SM--FAVSI--------------------NNDLYTIQAQLEVHKTDIIIIPPIQDD-FLKAQNQPFISWIKAQY-NGAQIISLCIGAFILAST-------GLL-GRKCVTHWRAAQPFKD---LFP--------------KVNLT------DKLLTDEQGIYTGGGAFSSANLLLYFI----------- +------------------------NQELYPVTSASAVFGYHHYSFSLC---A--LP--T---V--------------------PIQVDSGLE-A-LDD-DTVVIAG----P-S-P----VLHAVS-QA--GARIVAVCAGIFIPAAL-------GLLDGRRASVHWELFSELAA---RHP--------------RVIPG------TVIYVD-GDVATAGASAATLDLCLHQV----------- +------------------------DSVALEVAVAQQIFGPPPYEVVLC---G---L--L---L--------------------EVGHLASLD-A-MNT-DTVIVPG----L-T-R----VLASLD-CA--GARMVSFCGGAFLLAQA-------GILDSRRATTHWILTKEFRD---AFP--------------RVRLT------DHLYID-GPVHTSGGIFSATDLSLHLI----------- +------------------------GVPGHQLTTPGLVFSAADYDLRIC---A--NG--G---F--------------------RVETPWGLE-G-L---DTVLLPG----R--AE----VTAALH-AA--GCRIGAIGTGTFVLAAT-------GLLDGRAAATSRRHTEELAR---LHP--------------AIDVP------DGAVVS-GPFHSAAGVLGGVDLCLHLV----------- +------------------------GVRAFDVSVITEVWGTDAFDLRRV---A--VA--M---L--------------------TLLPDRTLG-W-LSR-DLIVIPG----L-T-P----VLDALR-RA--GTTIAALCGGAFTLAQA-------GLLDGRRAITHWNLIDLFRA---HHP--------------HVTVP------DALFIE-DNIWTAAGTAAGIDLCLHLV----------- +------------------------DCWGGLALLAREAFAIALFRVRLA---A--VR--S---P--------------------RLQPEAMLA-E-L---DAVIVPP----L-RQP----LQEWLL-QA--GAMLVGMAGGVRILAET-------GLLNGREVTGNLSDQRVFAL---HYP--------------EVRFP------DVPLVI-GSIISAGSVNPCLDACSYLV----------- +------------------------GVATFHLSIPQMVFGTVDWRVSLF---TPPVR--T---Y--------------------VLSGLGGPE-L-AGK-DVVVVPA----G-R-A----LCSLLK-AA--GANIVGLCLGAIPLAEA-------GLIGERRAVTHWRAFEPLAR---EHP--------------EIALE------SVLYVD-GDVLTSAGAASGLDACLHLV----------- +------------------------RTRPFDMASALEVFSLA-----IV---P--I-------T--------------------GSQPTCAFD-E-A---SVLVIPG----E-VPQ----EITFLQ-HA--GTTLVSLCTGAFWLASC-------GMLDGRIATTHWQYCEQLGE---QYP--------------AINVH------NVLYVQ-DNIWTSAGASAGTDACLSIT----------- +------------------------GCQSLDVIGPAEVFASAEYEVIIF---S--VK--T---L--------------------TLFAEESWQ-A-I---DTLVVPG----R-SYL----IFDWLR-NI--CRRVTSVCTGAFWLAEA-------GILNNRIATTHWRHCDTLQQ---RYP--------------EIKVS------DAIYIH-GNISTSAGITAGIDLCLSLV----------- +------------------------KVQLLDIAGPMDVFSEA-YKTILI---T--LQ--T---L--------------------RLLPDYAIH-N-DL--DTFLIAG----V-DVQ----LIRHLT-EI--SRRFGSICTGTFLLAKT-------NLLEGREVTTHWAFIEQLKD---AYP--------------YLNVN------QAFCVQ-KNMFTSAGVTSGLDLALTLI----------- +------------------------QFWSSTITSFAE-VFHGFQNSTFLRTDEP-VN--GFSGL--------------------NVGTERF---DPGTHFDVIIVPSVWDL-SVKKEVHDALLWLRQQH-AGCRVIGLVTGVFFLAEA-------GIL-GKQASVHWASKNTFKQ---RFP--------------KVQID------KSDITQSGHIITTSTTPAIFDVILLII----------- +------------------------GCMGMEVFALTDLVLMAALRVKLV---T--VA--I---F--------------------KVAAQRL---------DLIVVPG----RGRFA----ELKAIR-RF--GTELASVCIGSFVLAEA-------GVLQGRRAATAWPFVSEFQD---RYP--------------DVQIK------DAVILS-GGVTTTGAVSSVMDLGLHLI----------- +------------------------DVAFFELGCAVELFALPWYQCDLV---S--LT--T---F--------------------QICAR-QVD-N-LDA-STLVIPS----L-T-D----IAAAVT-RF--GKRVLSLCSGAFLLAEL-------GLLEGRQATTHWRYGEKFKS---RYP--------------GVDYD------DVLYVY-GQIGCSAGSSAAIDLCLEVI----------- +------------------------RFQLMDVAGPIAAFDFAAYVLTLC---A--VR--S---V--------------------SLEAE-AFG---S---DTVIVSG----G-DMD----VAQWLA-RE--AKRVASVCVGSYALAEA-------GLLDGIRATTHWGWIDDFAR---RYP--------------KVVVR------NAVFLR-DKYWTSAGISAGIEMAIALI----------- +------------------------DALASSVTLPMELSMAAIPNVLLVSNGGQ-VT--TSGGL--------------------KVETQAI---ETVGRLDLLVISAIWRD-PKRVKHPSLVPFIRRVA-SGTAIAAVGTGSFLLAET-------GLL-RKAATTHWFWFDEFAK---RYP--------------EVDLR------DQLIVQSNNLYCAGSVNSISDLLVFLM----------- +------------------------GSNPFEMSVATELFGL-WYDLTVC---A------V--MF--------------------TLGGLAGLE-A-VAK-DTVIVPN---PE-VPP----VVEAVR-AA--GARLVSFCSGAFTLAAA-------GVLDGRRAATHWRFEELFAR---TYP--------------RVRLR------DVLFVD-GRVLTAAGSAAALDLGLHLI----------- +------------------------SFSPFHVSVPYMIFGS-LFELFLI---A--AN--A---M--------------------FVQPDGGLE-L-LAT-DVVIVPG----D-E-K----VLYSLR-EA--GAYLVGLCYGTYALAYA-------GILDGKKACTHWLAEQDFKT---RFP--------------QIQLT------NALYSE-QRLITSAGTGASLDCCLYIV----------- +------------------------GCNDFVFNLPFSLFQMALFDMKVF---G--VQ--T---A--------------------KVQLDGHLE-Q-MDW-DIIVIAG----M--------FMQKLQ-VH--NKKIIALCYGTYALAYA-------GIATDKTLVTHWAGEAELKA---RFP--------------HIRLS------NRLYID-GNILTSAGALAGMDCCLYFI----------- +------------------------HATAISVAAPRDILNHATFRTDFV---G--VR--C---V--------------------WLTPHQVIG-N-D---DVILVPA-----DGLD----FIPWLR-QC--GAVLATWCGGAFMLAAA-------GILDGKTATTHWAMAEQLAS---QFP--------------QVNVP------DRMVVD-GDVITCGGATSFLNLGIYLI----------- +------------------------NISLFHLSIPCSIFGEDPYNVEVC---T--VD--T---F--------------------PITINKNLS-I-IAD-DTVIVPA----D-T-V----LLNAIN-NA--GARIVGLCLGAFVLAEA-------GILEGKTASTHWVWADEFAK---KYP--------------NVNFN------DVLYIN-DNVFTSAGSAAAIDCCLHIL----------- +------------------------GASLFEMSVPISVFGMDKFSLLPI---A--VI--S---V--------------------KIRAEYGLR-D-LDT-GIVIVPT----D-H-E-LERTVEAIR-NA--GAIVVGLCMGTFALAAA-------GLLHGRRAVTHWRHTAELAA---RYP--------------TVRVP------AVLYVD-GDVVTSAGGTAGLDACLHIV----------- +------------------------GVRPFQLSVPCEIFGEKETELWVC---A--LR--T---F--------------------IIDTAHGLE-D-IPS-NVVFIPS----Y-K-P----LVDALM-AA--GAIIVGLCLGAYVLAEL-------GLLDGKRATTHWAFSDDFRR---RFP--------------AVELE------KVLYVD-GTVLTSAGVTAGVDCCLHLA----------- +------------------------GVQLLDVTGPADVFATAAYVVEIA---A--IR--T---V--------------------RLVADVALA-D-VA--DTVLVPG----R-GPV----IVDWLR-AV--PHRIASVCAGAHMLAAA-------GLLDGRPATTHWFTAGRLAA---EFP--------------AVAVP------DPIFIR-GRVWTCAGVSSGMDLALAMV----------- +------------------------GVQLLDVTGPADVFTTAAYVVEIA---A--VR--T---V--------------------RLVADVALA-D-VA--DTVLVPG----R-GPV----IVDWLR-EV--PRRIASVCAGAHMLAAA-------GLLDGRPATTHWFTAGRLAA---EYP--------------AVAVP------DPIFIR-GRVWTCAGVSAGMDLALAMV----------- +------------------------GFWQVELASILSALNTARFPWQITSHPGI-VH--SNGDM--------------------MVRAGPS---IEQYLRQVLVVIGGTGS-HGG----GWMARLRAMQ-IKRRVVLLSGAATEYIKA-------TNP-SHPVTTNWSDVNVLSE---GGD--------------YPTLT------HLA-EDAGGIMTCAGGGHTLELMVAIL----------- +------------------------KFCDLELASVIHTLQTARFVWRIVSNPGF-VQ--GTGAC--------------------IVRAEPV---IDHCLADYLIVIASKTA-DTS----TWMARIRSMR-LGNAVILLADAATRFIAR-------TQI-TGAVTTHWADAVVLRE---TQD--------------LPRLE------SLS-ELSNGIITAAGRAATAELVIGLL----------- +------------------------RFCDLELASVIHTLQTAHFGWRVISRPGL-VQ--GGGVC--------------------LVRAEPV---INHCLADFLIVIASNTA-NPA----VWMARIRSMR-LGHSVILLADAATAFIAR-------TQV-TGAVTTHWADAVALRE---TQD--------------QPRLE------NLS-EFSNGIITAAGRAATAELVIGLL----------- +------------------------GFSALEVASVTHTLAEARFSWRFVSTPGR-VR--GAGGL--------------------TVRAEPA---IDYGFSDVMIVVGGPHG-DKP----AWLRRARAMQ-LGRPVVLLSDAATTYIKS-------TTS-AGAVTTHWRDISALQE---SGY--------------HPNLT------RFS-EVSDGIITAAGAGATAELLIGLI----------- +------------------------GFVLTEFSAVIEPLRLAPFQWTLRSAGGK-VG--CRAGA--------------------VVETDPFVP-RD---ADCVFVLGNSDP-DCP-A--SLGPEIATYR-RGAKVYLLAEAASRYIRD-------HAS-GRLHTTHWENATLLRE---RSG--------------LFDAN------FALASEDGQVVTCAGMGATVDVVLTLI----------- +------------------------NFTLLALSCMTEVLRHARQSWDLLSSTNP-IM--SSSGI--------------------AVTPNKTEC-DL-TGYDYIVIIGGKLP-KDC--PDAYIQFIKRCR-QGNKMIGMCTGTFALARA-------GIM-NVRTALHWYHYQEFKR---HFP--------------SSIAT------DELFIEDRGIITCAGGAASSDLALYLV----------- +------------------------EFTLLPYAAFIDKLRFSQQVWETRSTTEE-VF--SSAQS--------------------QHHASL----TDIQESDFIVFFGGRNV-QK-MESSDLRKIISLSY-ARTHIVAVDNAIFALGDG-------KLA-GNGVTVHWRHRQQFES---IFP--------------QIPVV------DKAFYIGQTFSSCVGGVAVMDLAIELL----------- +------------------------NFPILSLTLVTEPLRVALWRWRFLSVEG-SLT--SSSGI--------------------EIPTEALD----RSTADVVLLLSSYHP-ES-AVAGPLLSWLKRRA--GAVMGCVDTGALIFAEA-------GLLRSRPAAVHFEALRGYRE---KFG--------------DEMFA------DRLFDVTGNRCSSAGGVATFDMTLGLI----------- +------------------------GFSLLSVGGFLDKLRFSRQTWKLTADNQP-VT--ASCGA--------------------VLVPDEAVS-RHAGKCDYFVIFGGNMP-EK-ISTAPYLPLLRHLR-HHIPLVSVDNAAFLLAET-------GF--GKRILVHWRHFSEFKA---LFP--------------SIAPT------DKNVMEEGHVYSCPGGSATIELAAFLL----------- +------------------------EFSMLPFGGFLDKLRFSQQAWQIVGEPCH-LL--SSSGV--------------------SVEIKTT---EELADYDYLVVFGGRSA-RS-CQPKQYQDLLRLAA-KGVTLVSIDNACFLFAAA-------GLL-NHSVAVHWRHVQEFRT---AFP--------------RIDIT------EQLFCIDGKRISCAGGSAAIDLAVELL----------- +------------------------EFTLLPYAGFVDKLRFSQQEWDSFSDDEY-IQ--SSSGT--------------------VHKTKI----TTIKNTDFLVIFGGRNI-DA-MESGDLKPFIRACL-NQVHIVGIDNSIFPLALL-------GVF-NENVVVHWRHHDQFCD---MFP--------------KLSLP------DLLFYSKNKLSSCVGGTAAIDMAVSLL----------- +------------------------SFSLLALGGFIDKLRFTEQSWAVVGEHRQ--L--ASCGI--------------------HIEVDHL---DELQHVDYLVLFGSRTA-RQ-AQASLYASWLRKAA-HNMPLVAIDNATFTLAEL-------GLL-GYEATIHWRHEQEFRD---LYP--------------KIQVS------DRLFSFDRKRITCSGGSASVDLAAEIL----------- +------------------------AFTILPLAGFIDAVRHSRQHWDVLSDKEP-VC--SSSGL--------------------SIAPWKTYD-EA-GEYDYIVVVGGLID-QLD-GHADTFEFLQKQH-LGTKLVGLCTGSFAIAKA-------GLL-GKRAAIHAHHRPEFMA---MFP--------------ESIPE------NELYVSDDGILTCPGGTAAIDLAVEIL----------- +------------------------DFTLMSLSCFVEFLRLSRQSWDLLSEIAP-IR--ASCGF--------------------TMLPTRIFG-DP-TEYDYVVVHGGQLH-SST-PPDELYRFVQSCV-AGVPVVGLCTGQFVLAEL-------GYL-GKRCAVHFSLAQAMAV---HFP--------------DIEAT------DASVVADGGFITCPGGLAAINLAMHLV----------- +------------------------------MASFVDALRLARQAWDFISGPSP-VR--ASCGL--------------------EMTPTGNLD-DP-EAYDCIAVCGGLIR-DLG-GHQATFEYLRAAN-RGIPLVGLCTGSFVLAQA-------GLL-HRECALHFDTLGEFLS---RFP--------------NSNPT------SQNYIIDGNIITCPGSIVAIDIAVFLI----------- +------------------------EFTLLPFTCLVESLRHAHQRWSLVADLRP-IR--SSCGL--------------------EMLPNEIFP-AC-EGFDYIIVIGGRMP-FAL-EDEASREYLRQAI-ADVPVVGVDNGAMLLAQM-------GML-GRECAIHFFHRVQLQT---DFP--------------LVVPT------DRPFVDLGDIITCPGGAMALDLAVYLV----------- +------------------------KFTLHCVSELIEPIRFARQQWEWMSDNQP-VT--SSCGL--------------------QITPTAPFN---DDQWDYVVFAGGLLD-E--TDPAWLLETMRSLQ-RRIPIITLCSATFMAAQA-------GLL-GKKCAIHFTTRDEFRQ---RFP--------------SVTPI------DQTYLSDGGIISCPVGTA-RDLAMDII----------- +------------------------KFTLAPVSGFVESLRFALQKWDWMTNNLP-VN--ASCGL--------------------SVNPSKDMD-QLKQNYDYIVIAGGLLS-E--TKPEYLLEALKEIH-AKIPIIALCSGCFVLGNA-------GLL-GRKCAIHFTTRDEFAG---LFP--------------KAITI------EQTYIEDHGIFTCPGGTA-IDLAADLI----------- +------------------------EFPLLALAGLTDALRHAQKSWRLMSTPQP-VL--SSSGM--------------------AMMPDSAFV-AP-EQFDYIVVIGGLLR-SMA-KDPAARRYLHLAR-RNIPLVGVCTGSFVLAQE-------GFL-GLTAAVHPWHLNDFKA---QFP--------------LLTAT------GVDFHEEKGILTCPGGISTIGLATELI----------- +------------------------SFPMMSLAGIVESLRHAHPRWDVLGPGSR-AM--SSCGI--------------------PVEATTPYG-QP-EAFDYIFVIGGLLR-DLP-NPDGHRNFLRAAG-AGSVIIGVCTGIFVLARE-------GLL-GKTVCVHPYHQTDFET---AFP--------------HLRPF------DKDYVSAGNIITVLGGVSILALTARII----------- +------------------------RFPLLSLAGLCDALRHARPAWTVAGEGET-IE--ASCGI--------------------PVPVQEAFP-DP-ARFDYLVVIGGLLP-QLE--DPRYWAYLRRAA-AGVPLVGLCTGSFVLAQA-------GLM-DRVACIHSFHVDDYRE---RFP--------------ALRLT------HADYLIDGERITCAGGISIVELATRLI----------- +------------------------RFSLLALSGLMEALRNAKTDITLISHPIP-LC--SNVGV--------------------SIRPDAAHA-PP-EHFNYVAVIGGGLK-YLA-QYPGDREYLAHAH-MNVPLIGIGTGSFVLAQE-------GLL-ERRASIHPFHLEIFQH---AFP--------------QVYAQ------GYDFINEGDVLTCPGGISTITLATELI----------- +------------------------GFTLSALSLFLDPFRLARQAWKICTSGDP-VT--SSSGM--------------------VIEPTAPIG-E-LDDCDYVAVVGGLLA-QYRP-QQALVDLIKRAD-RGKTVVGLCTAAFLLAEA-------DLL-DRNCCVSWFHRDDFLE---LFD--------------GYTAT------TSLFHRSGRHFTCAGGLGTASLALSII----------- +------------------------SFTLSPFALFIDTLRLAGRDWHVLGTRHL-IT--SSCGV--------------------QIAPTSDFI-DP-SNFDYIVVVGGLLR-VPE--DHATMTFLKSAA-KGVRMIGVCTGSFILAEA-------GLL-GHEVCVSWLHYQAFQE---RFP--------------HLVVP------DRLFHLEGRRGSCAGGSSSADLANVIV----------- +------------------------RFTLGAFANFVDVLRLARPQWRVLSD-SP-IL--SSCGV--------------------AISPHERIG-DL-RRFDYLVVVGGVLE-EES-LDARFDDHLRHAA-AGIPLVGLCTGSFVLHRA-------GLM-GYKCCVSWFHGSDFLR---LFD--------------GLQAS------DQIFVVDRDRLTCSGGASAAHLAAFLV----------- +------------------------RFTLCAFANFVDVLRLARPNWTVLSR-DP-IT--SSSGI--------------------TVQPKERLG-DP-RRFNYIVVVGGLMD-EAP--SPAYQKFLHEAA-AGVPLVGVCTGAFLLHEA-------GLL-GYRCCISWFHHSEVVD---QFE--------------GLDPT------EQIFVVDRDRLTCSGGVSSAHLAAYLV----------- +------------------------NFTLTALSGFLDVLRLSRPTWQVIGT-SP-IR--ASSGV--------------------HVSPSARFD-DA-GQFEYIVVVGGLLH-SSP--SPATLEFIRAAG-SEATLVGVCTGAFALMRA-------GVL-DARICVSWFHYWDFLE---QFP--------------HVTPA------DRLYVFDHRRITCSGGRASIDVAAAIL----------- +------------------------QFTLAAFAGLVDVLRLARQHWRVMSDGLP-RE--SSAGV--------------------AVNVDGALP-DP-AAFDYIAMCGGNDY-PNT--PPPLRDWLQLAS-KHVRMLGICTGTFTLAQA-------GLI-SRTVCVHWNVLDAFRS---RFA--------------QTKAV------DHLFVDEGDLITCAGSTAAIDLGLYLV----------- +------------------------GFPMACLTSAIEPLRAAEFRWILLAETARPVR--ASAEL--------------------RFEPDMPLA-ER--GVDQLYLLSPPTG-RF-ADPRHSPARLRWLD-TGVVLGAFSGGIFPLARA-------GLMEGRGCSVHWCYEAAFRA---EFP--------------DVRAS------EQVIVK-GRRITASGAGAVFDLMLRLV----------- +------------------------GLCTFEFGVAVEIFGL-WYQFAVA---A---C-----GI--------------------RLMTDGGPE-L-LAQ-DTIVVPG----D-APV----LCAALV-AA--GCRIISICSGVFVLAAA-------GLLNGRQATTHWRYTAALQS---RFP--------------QIQVE------DVLYVG-ALLMTSAGSAAGIDLCLHLV----------- +------------------------------------------------------------------------------------------------HHYDAVMMPGGPKGTDSLTANPQVIAFLRRHIAQDKYICALCSSGAKVLAAH------HLLAGRTYSTGDKLAD---------------------KFADGAYL------DQDVVVDGKFITAKGLGVSFEFAFTV------------ +---------------------------DYGINIPFRALQALGCKGDTVTPNKKKGEVCATVVYDLEDE--------S----LDNFFVTASWDGVCVDDYKCVVLPRGR--------------------------------------------------------------------------------------------------------------------------------------- +----------------------FPAFEMLDVFGPLEVLSWAARLHYLLAETLD----PVTTQPQ------SAAMNTFNSSFFPTVNPTHTFDDN-P-ELDVLIVPGGLGTRNPNM-DRT-LQFISSTYPRVQYLITVCTGSALVAQT-------GILDGRRATTNKASWDSV-------------------IVNGTTWVP-----EARWVVDGNIWTSSGISAGI------------------ +----------------------SRAFEMLDVFGPLDALGMLARIHYLIAETMD----PVTVEPV------SAAMNAKNSSFFPKILPTHTFATA-PTDIEVLMIPGGLWTRSPNL-NST-IAYVRATYPKLRYLVSICTGASIAARA-------GVLDGRRATTNKASWAST-------------------IAYGVTWVP-----KARWVVDGNVWTSSGISAGI------------------ +----------------------FQAFETLDVFGPLDALQILSRNHSLSSNTLD----PVTTRPR------APGMNPRNSSFSQSVLPTHTIKDA-P-DLDVLIIPGGLGTRAPDL-NAM-IDYIRTTYPKLQYLITVCTGTGLVAQA-------GILNGRRATTNKSSWAST-------------------VALGVKWQG-----HARWTVDGNIWTSSGISAGI------------------ +----------------------ARAFEMLDVFGPLDALGMLARSYYLIADTMD----PVTVQPV------AAAMNAKNSSFFPSILPTHTFATA-PKDIEVLMVPGGLWTRSPNL-NAT-ISYIRATYPSLRYLVSICTGASVVARA-------GVLDGRRATTNKASWAST-------------------VVHGVTWVP-----KARWVVDGNVWTSSGISAGI------------------ +----------------------PRAFDIIDIFGPFEVFQALSRKTDMLARTLE----PVKTEPV------AA--NQFNSSFYPTFNPTHTFADN--PPLDVLVVPGGAAARSPL--GPE-IEYIKKVFSSLKYFITICTGAGIAAQS-------GVLDGHRATTNKAAWNTM-------------------TPMGVKWVS-----PARWVEDGKVWSSSGVTAGI------------------ +----------------------YPGFQALDAFGPLDILNIVALEKSLIAPTMD----PVSTKSP------IPNTNSNNSTSYQSVVPTHTYDAP-PENIDVILIPGGIGSRHETI-KPT-VKFLAERFPHVRYLLTICTGSYVAAQS-------GVLDGKKATTNKLRYDAV-------------------VAMTVNWVR-----QARWVVDGKIWTSSGVSAGM------------------ +----------------------YPGFQALDAFGPLDILNIVALEKSLIGPTMD----PVSTKSP------IPNTYSTGSTSYQSVVPTHTYDAP-PEDIDVIIVPGGVGSRHETI-KPT-VQFLAESYPRVRYLLTVCTGSYVAAQS-------GILDGKKATTNKIRYDAV-------------------VAKAVNWVR-----QARWVVDGNIWTSSGVSAGM------------------ +----------------------FPGFQALDAFGPLDILNVISLDKSIIGPTLD----PVSTKSP------VLNTNPQNSTSHQSIVPTHTYDAP-PENIEVLLVPGGFGTRCKTS-AAT-IKFIADTYSHVRYLLTVCTGAYLAAQS-------GVLDGKNATTNKVMFNFV-------------------AKKNVKWVR-----KARWVVDGNIWTSSGISAGI------------------ +----------------------FPGFQALDVFGPLDVFNSLAMLYT-LAKTSD----PVETSHQ------RA--------TMFSHP--------E--AIDVLIVPGGVGTRGD---STE-IDFVKRIYPNLKAVLCVCTGATILARA-------GILDGRRATTNKRAFAWA-------------------TSTGVKWVP-----EARWVVDGNIVTGSGISAGI------------------ +----------------------FPGFQALDVFGPVDVFNSLSMLYT-LAKTSG----SVETSHQ------RA--------MMYSHP--------DSLAIDVLIVPGGVGTRGD---SAE-IDFVRAIYPRLKAILCVCTGATILARA-------GVLDGRRATTNKRAFAWA-------------------TSTGVKWVS-----EARWVVDGNIVTGSGISAGI------------------ +----------------------FDHFQALDVFGPMDIFNNLAMFYYLLSKTMA----PPTTGMK------MA--------MEQKIVPTVTFQEYLPGEIEVLIIPGGGGTRNN---TEE-IAFVKAMYPKLKYILTICTGATIASRA-------GILDGRNATTNKRSWTWA-------------------VAQGVTWAP-----TARWVEDGNIFTSSGVSAGI------------------ +----------------------FRSFEILDAYGPIEILQFVSHFHLIRS---A----PVLTSPT------LPSMNPQNSSFYPTFNPTHAIPTSELESVDVLLVPGGMGVYNPLERGGE-LEFLRRMRRKDKYLVTVCNGAAVAARA-------GVLDGRRATTNKMVWGEV-------------------TPLGVKWVS-----PARWVVDDNIWTSSGVTSGL------------------ +----------------------PRGFSALDVFGPLEVFQALSRTGRLLARSLE----PVTTEPP------FQTFPLPPRGFHARLLPTHTYSVP-PQSIDVLLVPGGAAARSPL--GTE-IEFIRAVFPKLQYLITICTGAGIAAQA-------GVLDGRRATTNKAAWGVI-------------------TAMGVRWVS-----PARWVDDGKV------TAGI------------------ +----------------------FPTFEILDAYGPIEILQFVGHFHLILQSGLA----PVLTTPS------LAINNPLNSSFYPTFNPTHPIPTTDLESVDVLMVPGGEGVYSPLEGGRE-LDFLRRMVGKDKYLVTVCIGAAVAARA-------GVLDGRRATTNKMVWGEV-------------------TALGVKWVS-----PARWVVDGNIWTSSGVTAGL------------------ +----------------------------LDFIGPYEPLNLPNVNVVLVSHSKGIIRAEKSLI---------------------GFEATATFDEV--QEPDIVIVPGGYG-VNALIRDKPILDWIRKTHEKTLYTTSVCTGSLLLAAA-------GILNGLEATCHWRVLP-------------------ELSKFGAKPT------SSRIVESGKIITAAGVSAGIDMG--------------- +------------------------------------------------------------------------------------IAATTTFADCP--DELDAFVVGA-V-PADVIADDEVIAFVRRQASRARYVIGICGGVLLLGAA-------GLLNGRRATTNFH-------------------VLDALAELGARPV------GGEVVIDGNLYTAGPATGGFEAA--------------- +-------------------------FRDEEFFETKRALDAAGVQTVIASTRIGIIR--GMLGIA---------------------EANILVGQLRVEDYNAIIFIGGPGAV-EYAVNPAALNLAREAVRQRKILAAIDTAPTILANA-------GVLTGVRATSFLSERN------------------------------------------------------------------------- +------------------------------------------------------------------------------------------VKDSVKDNVDGLIIPGGWNG--ELR--LELIELIKNVNSQGKLLGAICGGPYFLAKS-------NILQNRKYTTSMIEWTEMHK--QQYEEIDPFPR--------ENFVN------KRVVVDENLITSQGVA--------------------- +------------------------------------------------------------------------------------------VKDVLAEIADGLIIPGGWNG--ELK--SELVELIENINSQGKLLGAICGGPYFLAKA-------NILQSRKYTTSMIEWTENYK--QQYEEFDPFPR--------ENFVN------ERVVVNENLITAQGVA--------------------- +-----------------------------------------------------------------------------------------------RPSQTALFVPGVQMKVPDLDQCTEELNCIARYHSQGRVVAASFNGPVMLARA-------GVLDGRRATV-------------------TWMIANWFASSAVQLAM-----EGPVVVDGLVFTAGAPAAVCDLMVELIRH--------- +-----------------------------------------------------------------------------------------------AAARCALLVPGLDMDVPQLDRADKALRLIALRHAAGDVIATNYNGAALLARA-------GILDGRNATI-------------------TWLIAGWFSSSKVNLLM-----DRPVTQDGGVFCSGAPAAATELVLELVRH--------- +-----------------------------------------------------------------------------------------------QAALSALLVPGLDMDVPQLDQSGKAQQMIARRHAAGDVIATNYNGAALLARA-------GILDGRNATI-------------------SWMIAGWFSSSRVHLLM-----DRPVTQDHGIYCSGAPASSTELLLELVRH--------- +-----------------------------------------------------------------------------------------------PPSRNALLVPGLMMRVPDLDQAEAECACIARYHAQGRVIAAAVNGTALLARA-------GVLDGRKATT-------------------SWIIVNWFAGRGVKLTM-----DGPVVEDGTLFTVGAPSAHYDLAVALVRH--------- +-----------------------------------------------------------------------------------------------QLGDA-LIVPPLHFDIGTLALLEAERATVRRYLDAGRLVASPFTGVAMLAD--------VLPPGQRLTV-------------------TWLIAGWVQGNSLKVVP-----AQAIVSSGNVITARAMEHGVALMHRVVAR--------- +-----------------------------------------------------------------------------------------------AGRDAMVVIAPPLFDIAGLSLLDRERTAIAAVARRGALVVAPFTAVALLVAM-------DLPAQRKLAV-------------------PWLIANWMRQCARRLQA-----DQPVVKSGNLLSSRALDRMHALLRQAVAH--------- +-----------------------------------------------------------------------------------------------ADKNAMVVIAPPIFDIAGLSLLDRERAAIASAAAKGALLVAPFTAVALLVNL-------GLPAQRRLAV-------------------PWVFGTWMRQVARRLQA-----DQAVVKSGNVFSSRALDHVHALLQQAVAR--------- +-----------------------------------------------------------------------------------------------PEALDVVVIPGWLVPGPQSQRYSQHGAMLRGHLQRGGLVAALFNGSSLLAHC-------GLLAGRKAAL-------------------PWVFAPSIVLQESGAQR-----ERTWQRDGALWTTASLQDTPAAMLDLLAQ--------- +-----------------------------------------------------------------------------------------------QGPLHVVVVPGWLVPGPQCDRHAAHGPLLRSHVAGGGLVAALFNGSALLADC-------GLQAGRKVAV-------------------PWVFAPSIFMQDTGQQR-----HQGWQRDGALWTTASLQETIAAMLDLLAC--------- +------------------------------------------------------------------------------------------------REVDVLVVPGFELTGQDIANLAPEIEAIRSHAAAGDVVVSLCVGAFLLAAA-------GLLDRRRATT-------------------SWLFADELARREAEVRP-----ERLVVTDRGVTTTAAFSAMYDFALELIRE--------- +------------------------------------------------------------------------------------------------REVDVLVVPGFELVGLDLASLAPEVAAIHSHAAAGHVVVSICVGAFLLAEA-------GLLKGRRATT-------------------SWLFADELARRDADVRP-----ERLVVTDKGVTTTAAFSAMYDFALELIRR--------- +------------------------------------------------------------------------------------------------REVDVLVVPGFEHMGQDLARLAGEVEAIRSHAAAGNVVVSICVGAFLLAEA-------GLLDHRRVTT-------------------SWLFADELARREALVQP-----EHLVVTDRGVTTTAAFSAMYDFALGLIRE--------- +-----------------------------------------------------------------------------------------------GDGIDVLVIPGFEFIGENLADLAPEIEVIGRHVRDGRPVASVCVGAFLVGAA-------GVLDGRTVTT-------------------AWLFADALRQACAVVDD-----EKLVVTDGGVTTTAAFSAMYDFVIDLIES--------- +------------------------------------------------------------------------------------------------REVDVLVVPGFELRNADLARLAPEIAAIRAQAAAGTAVVSLCVGAFLLAEA-------GLLDRRRATT-------------------SWLHAGELARREADVRP-----EHLVVTDTGVTTTAAFSAMYDFAMDLIRR--------- +------------------------------------------------------------------------------------------------REVDVLVVPGFELRDTDLARLAPEIAAIRAQAAAGTAVVSLCVGAFLLAEA-------GLLDRRRATT-------------------SWLHAGELARRDAEVRP-----EHLVVTDTGVTTTAAFSAMYDFALDLIRR--------- +-----------------------------------------------------------------------------------------------GEAHSLLVIPGVMARAPHFEQQRPVLKLVERHAQAGGWIAASFNGIAYAAEL-------GLLDGARIGA-------------------PWLYQSWMARRLCDFTH-----DEPMGVHGRVFHSVAPALQTEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------EDGNALVVVPGVLARAPHLGGSGQALRLLERHAQAGGWIAAGASGIAFPAEL-------GLLDGARMGA-------------------PWTFQSWMAKRRCDFSA-----SEPMGLHQRVFGCVAPALQTEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------ADRRTLLVIPALLASALQVKRDAAALRLVERHAQAGGWIAACSSGMVFPLQL-------GLLDGARTGA-------------------PWMYQSWMMRQHCDLGS-----DQAMSVHQRVFSCVAPALQVEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------RHGRTLMIVPGLMAHAPHVTNDTVTQRTIARHVDAGGWLAAIYSGVVYPLAL-------GLLDGARCGA-------------------PWMFQSSLAQRGCDLSS-----DEPIGLHERVFHCVAPALLTEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------EDGNALVVVPGVLARAPHLGGAGQALRLLERHAQAGGWIAAGASGIAFPAEL-------GLLDGARMGA-------------------PWTFQSWMSQRRCDFSA-----SEPMGLHQRVFGCVAPALQTEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------RGSRTLLVIPALLASAPQALRDTAALRLVERHARAGGWIAACASGMVLPLQL-------GLLDGASVGA-------------------PWMYQSWMARQHCDLTS-----DAAMSVHGHVFSCVAPALQVEFMLRVLGH--------- +-----------------------------------------------------------------------------------------------PQGTQLVLVPGLGLAVGEMVQPEALITALR-QIPNETPIAAACSATFALGAA-------GLLDGQHTTG-------------------PWWLMPHLAHLRAKLRQ-----GDLIVEDGRITTAGAAFGQIDLMLHLITR--------- +-----------------------------------------------------------------------------------------------APPADLLVVPGLGFAPDALARPQAAGVRLAAAVAGGAEVAAACSSVFLLAAA-------GLLDGRRATT-------------------SWWLAPLFARMQVRLDP-----DALVVRDGPVTTAGAAMAQMDLMLQVVAR--------- +-----------------------------------------------------------------------------------------------TDQVDLVVVPGLGMRTQELAAPRAGAHYLNAAAAAGSEIAASCAGVFLLAEA-------GILDQRRATT-------------------TWWPAPLFARRAVRLTP-----ADLVVTDGPVTTAGAALAHLDLMLTLVGR--------- +------------------------------------------------------------------------------------------------TAFDLLVVPAFDFNGEDLAGLEEEKTLIRRA-AEQRKVASICGGSLLLAET-------GILDGRQATT-------------------AWALAGEMARRQVDVVP-----DAVLVRDGEIVTCGAFTAYGDLALQLIRD--------- +-----------------------------------------------------------------------------------------------VRGADVVVVPWWGEPRAA---PDELSSALREAHDEGAELVGLCLGAFPLADS-------GVLEGRTATT-------------------HWKWADVFRHRRVALEP-----DELYIDQGQIVTGAGATAGIDACLHLLAR--------- +-----------------------------------------------------------------------------------------------ADTAGTIVIPSWER-RPL---PEPIREALHRAHARGARIVGLCLGAWAVAAS-------GLADGREITT-------------------HWSAAAELGRAAVRVRA-----DTLWSDDGDIITSAGVAAALDCCLHVVRS--------- +-----------------------------------------------------------------------------------------------LLDADIVIVPSWRDEETP---PDELLDAVRAAAARGAQLVGLCLGAYVLAAA-------GLLDGRPATT-------------------HWAWADDFARRRVKLDP-----DVLYVDDGNLMTSAGTAAGLDCCLHVVRR--------- +-----------------------------------------------------------------------------------------------RQVPDLFFMPGWLAQGPHITSNTPLRTRLQQVHDHGGLIIAVGNSSPALGYA-------GLIADGEAVC-------------------PWAFIPTFRRLDITLRA-----DLMWTQHQRTWTCNSPVLATELVLDALKS--------- +-----------------------------------------------------------------------------------------------VGTYDLLIVPGLETQHPDLAPLSAECQFIQNSFARGTTVAAVCIGAFLLGEA-------GLLDGRKVTT-------------------AWLFSADLATRAAKLEA-----DAILMQDGAVITTAAVSSAFDLAIHLVKL--------- +-----------------------------------------------------------------------------------------------HHDIDHLVVPGFDLVSEDLSLWDREIEFIRACEARGVRVSSVCVGAYLLGEA-------GLLDGRRCTT-------------------SWLYGADLASRGATVRT-----DSLIVQDDGVTTTAAFTAALDLATALVRE--------- +-----------------------------------------------------------------------------------------------YHRFDRLIVPGFELVSEDLGSLHREATFLRAAAERGTRIASVCVGAFLLGEA-------GLLDGRRATT-------------------SWLFAPRLARRRATVCP-----EALIVTDGTITTTAAFSAALDLATALVRE--------- +-----------------------------------------------------------------------------------------------HHRFDLLVVPGFELTDTDLGDRSREIAFLRAAGRRRIRIASVCVGAFLLGEA-------GLLDERRCTT-------------------SWLFASKLARRRSTVCA-----ESLIVTDEQITTTAAFSASLDLATAIVRE--------- +-----------------------------------------------------------------------------------------------DHTIDLLVVPGFDLSEQDLPKLSAEVALLRRSAARGIPTASICGGAFLLGAA-------GLLDGRRATT-------------------AWLFADELARRSSSIDP-----RALLVEDGPITTTGAFSASLDLAMHLVRV--------- +-----------------------------------------------------------------------------------------------RRDHDLLVVPGFDLSTEDLGDRHREIALIREAGRRGVRVASVCVGAFLLGEA-------GLLDGRRSTT-------------------SWLFASQLAGRLSTVCA-----QSLVVTDEHVTTTAAFSASLDLATTIVRD--------- +-----------------------------------------------------------------------------------------------HHRFDLIVVPGFDVSTDDLADRSREVAFLREAASRRIRIASVCVGAFLLGEA-------GLLDGRRSTT-------------------SWLFASQLTRRRSTVCA-----ESLIVSDGLVTTSAAFSASLDLTTAIVRD--------- +------------------------------------------------------------------------------------------------RPVDVLIVPGFELSTLDLADLGPEAASIRSQAASGTAVVSICVGAFLIAEA-------GLLDGREATT-------------------SWLFADRFARRDVRLRP-----DSLVVTDRGVTTTAAFSAMYDFALQFIRA--------- +------------------------------------------------------------------------------------------------GEVDVLVVPGFELRGTDLGGLTPETAAIRAQAAAGTAVVSLCVGAFLLAEA-------GLLDRRRATT-------------------SWLHAGELARREAEVQP-----QHLVVTDRGVTTTAAFSAMYDFTLDLIRR--------- +------------------------------------------------------------------------------------------------RPVDVLVVPGFELHGLDLASLRPEIETIRSASQSGVALVSICVGAFLLADA-------GLLDGRESTT-------------------SWLFADRLADRGTAVRP-----EKLVVTDSGVTTTGAFSAMYDFALGLIRE--------- +------------------------------------------------------------------------------------------------RPVDVLIVPGFELSTIDLARLGPEVASIRSQAASGAAVVSICVGAFLVAEA-------GLLAGREATT-------------------SWLFADRFARRDVCLRP-----ESLVVTDGGVTTTAAFSAMYDFALRLIRE--------- +------------------------------------------------------------------------------------------------RPVDVLVVPGFELSALDLADLRPEVAAIHSQAVSGAAVVSICVGAFLTAEA-------GLLDGREATT-------------------SWLFADRLARRDVKVRP-----ERLVVTDRGVTTTAAFSAMYDYALQLIRE--------- +-----------------------------------------------------------------------------------------------AAIPAVIAVPGQVSSTASLRTDEILLDWLRAHYDGGSLLAAAADGVSVLARA-------GLLAGRTVSG-------------------PDL------SRGLVAPS-----ERALVDDGDLLTVAGVQAWRFLGLRLLHR--------- +------------------------------------------------------------------------------------------------LQSDAVILASAMVTKSELHDFDPLFEPLRLFAGSGKPLAAYCSGTLILAAS-------GLLDGREATT-------------------VWWLNEMFQRHKVNLRM-----DKLVVSDGHVHTAGATTSNMSLALHLVHI--------- +------------------------------------------------------------------------------------------------LEADAVIVASSLVTKAEAQDFLPLLGPLSAYAKTGKPIAAYCSGTLMLAAS-------GLLDNRRATT-------------------VWWLSQMFERNRVNLCM-----DSLVVSDGQFHTAGATTSNLSLALHLVGL--------- +------------------------------------------------------------------------------------------------LQADAVILASAFVTRTELTDFEPLIAPLSRFSAAEKPVAAYCSATLLLAAS-------GLLNQRRATT-------------------VWWLSEMFERNDVQLCM-----DSLVVSDGHIHTAGATTSNLSLALHLISI--------- +------------------------------------------------------------------------------------------------LQADAVILASAFVTREDLNEFEPLFEPLRVFAASGKPVAAYCSGTLMLAAS-------GVLNGRRATT-------------------VWWLKEMFQRNDVNLCM-----DKLVISDEHIHTAGATTSNLSLALHLIGI--------- +------------------------------------------------------------------------------------------------LNADAVILASAFVTREELEDFTPLFKPLTLFAASEKPLAAYCSGTMMLAAS-------GLLNGRRATT-------------------VWWLSEMFERNKVSLCL-----EHLVVSDGHLHTAGATTSNLSLALHIIGL--------- +-----------------------------------------------------------------------------------------------LARYAAVILPGFFADVASLQTLQPAMARLR-TVRPGTPVAASCYGTFVLAES-------GLLDGRHATT-------------------TWWLQAVFRQRAIHLDA-----DRVLVDDGNAITAGAMTAHTDLSLHMLRR--------- +-----------------------------------------------------------------------------------------------APEADLILLPGIHHASRSVKALDKIGRWVNSRIEQGEAVAANCSGVLLLAEQ-------GVLDNQEATT-------------------AWWLADLFRKRQVRHIS-----DKLLVKSDRICTTGSMSANLGVMLQFAEE--------- +-----------------------------------------------------------------------------------------------DRALDLLLVPGFMHDVGDIAGYGPEIELLRAVSLRGVPLAANCCGSLLLAEA-------GLLDGRGATT-------------------SWWLDGAFRERRVRLDV-----QRMVCDEGDIATTGASTAVMGYVLQVLAR--------- +-----------------------------------------------------------------------------------------------PEDIDVLLIPGVMHSVHDIQRMQPEMELIRAMHLRGVAIAGTCSGSLLLAES-------GLLDGHRATC-------------------SWWLAPAFRHRAVTLEA-----DAMVVEDGGVMTAGGSSALQAFMLRLIGK--------- +-----------------------------------------------------------------------------------------------PAGLDLLLVPGYMHAAEDLADYGPEIARVRAEAERGVPIAASCCGAFLLAEA-------GLLDGRSATT-------------------SWWLASAFRRRKVRLEI-----DRMVVEDGPFTTTGASTAVLGFVLQWLAR--------- +-----------------------------------------------------------------------------------------------EVALDLLLVPGYMHSAGDLAGFGPEIALLRAMHLRGVPIAANCCGTFLLAEA-------GLLDGRHATT-------------------SWWLDAAFRQRRVKLDI-----ERMVVEDGGVTTTGASTAVLSYILQLLAQ--------- +-----------------------------------------------------------------------------------------------DHALDVLVVPGYMHSAHDLGQYGPEIELLRALSLRGVPLAASCCGAFLLAEA-------GLLDGHEATT-------------------SWWLDGAFRRRRVKLSV-----DRMVVEDDGVTTTGASTAVMGYMLQLLAR--------- +-----------------------------------------------------------------------------------------------LSHADAVVVAASTITRKELRAFSPHMPTLHQFAETGKPIAAYCAGTLVLAAS-------GLLDGRTATC-------------------VWWLAELFKRRKVNLCM-----EHLVMSDGPMYTAGATTANLSLALQLVKV--------- +------------------------------------------------------------------------------------------------KEMDAVIVASMIIREECLRNFAPFTHALLEFKKLKRPISAYCTGSLALAST-------GLLNEHQATC-------------------AWWLSTMFTNRKVILTM-----NKIVVADKGMFTAGAASANLSLALVLVRE--------- +-----------------------------------------------------------------------------------------------FSHADALVVASATITRKQLDDFQPHIATLKKFAQTNKPIAAYCSGTLMLAAS-------GLLDDKKATC-------------------VWWLAELFRRSRVDLCS-----EHVVMNDGQYYTAGATSANLSLALQLVQK--------- +-----------------------------------------------------------------------------------------------LTQVDALVISAPLILGRDLASFKAFEDHIKALADNGVPVAACCAGAFLLAAT-------GLLDGRKATT-------------------AWWLAPLFEQHEVRLSM-----VSLVERDGLFFTAGASTASYSLGLALLEQ--------- +-----------------------------------------------------------------------------------------------WLQADAVVVAPAYAYRAQAEPSKAYFSGLRQAVANGKLIAANCTGTFILAAS-------GLLAHKNATS-------------------SWFFKDVFQNLEVHLQL-----NKLLVQDGNILTAGATTSFVNLCLALTEL--------- +-----------------------------------------------------------------------------------------------WQEADAIILPPAYAYRAQAEPSRPYLAGLLDVAQSGKLIAANCTGTFILAAS-------GLLAHKRATT-------------------SWFFKDAFQSLDVHLQL-----NKLLVQDDNLLTAGATTSNINLCLAITER--------- +-----------------------------------------------------------------------------------------------FNQIDILLIPGFYAYSKDSQELLPYKTELQQMLQQGKWLGAFCNGTFALAGT-------GLLNGLQATS-------------------VWFFKDYFRQMLVKLDL-----QQLVVQQQTILTGGATTSYLNLCLRFVEM--------- +-----------------------------------------------------------------------------------------------DEAFDLVFIPGLYYARAALDASAPQREWLRAQWQGGAMLAANCTGTFVLAET-------GLLQGKTATT-------------------TWWLERLFRARSIDLQL-----RAMVTEADRLCCAGASASYLLQAVRMVEH--------- +-----------------------------------------------------------------------------------------------EEKLDIIFIPGLYYSHDGLEAAEPQREWLKAQWREGAALAANCTGTFLLAET-------GLLRGRQATT-------------------TWWLERLFRERGVNLQL-----RSMVTEEDRLWCAGASASYLLQAVRMVEH--------- +-----------------------------------------------------------------------------------------------RAMERAILVPPLETVVPQVASNEAVLREIRGAVADGRYVCAIGTGVWLVAAA-------GVLDKMQAPV-------------------QWAYQSGFARADLAIAN-----DPIVWANERILLAGTPSLAYDCVLELMER--------- +-----------------------------------------------------------------------------------------------PDELDALIVPGIAHPKPGLVDLVAEQHCIARFAAAGRLVLGTCSGVFLIGAS-------GALDQRKATT-------------------SWWLGAEFARLDVRMSA-----ESALIHDGNCVSAGGVAAYYDLALWLVQH--------- +-----------------------------------------------------------------------------------------------TAKPDALMLPGIDHGLHDLKQLKAESDAVQAFTPSGQLLVASCSSACLLAHA-------GLLDGRRATT-------------------SWWLAAYFRQQLVTLDA-----EELIVQDGQFVTSGGVTSSLDLALWLVGH--------- +-----------------------------------------------------------------------------------------------APATALAVVPPLMMVIPGVAQNAALCAQLASRHAAGDWIGACGTGLWLAARA-------GLLAHQPVPL-------------------SWLYQSGFAHDDTPIHS-----ETPLTLGPHMVLAATPDLMHAMVLKLLDG--------- +-----------------------------------------------------------------------------------------------RAPAQALFIPSFHAPIPAAGRYGALSRQLGIAVDAGCKLVTVGNGAWLAAHS-------GRLNGCQASL-------------------PWFYIAGFERDGIGLSL-----GQDVSDDGPWLSGALPHSVNLLAIALVRH--------- +-----------------------------------------------------------------------------------------------PGSAQAVFIPSFLAAIPAVARHPALVRQVGIAVDAGQKLLTMGDGAWLAAAS-------GRLQGRTASL-------------------PWFYMAGFARDGIALVP-----GRDWTDDGPWLSGALPHNLVDLAIALVRH--------- +-----------------------------------------------------------------------------------------------DGPALAWFIPSFHAAIPAAARHRALSRQIGIALDAGHKVLTVGNGAWLAAQS-------GRLQGRRGCL-------------------PWFYLAGFERDEVVLDA-----GHDLSDDGSWLSCALPHSLGEMAVALVRH--------- +-----------------------------------------------------------------------------------------------LAPTRALFIPSFHAPIPAAARHQALSRQLGIALDAGQKLLTMGNGAWLAAQS-------GRLNGRQACL-------------------PWFYIAGFERDSIGHSL-----GQDLSDDGPWMSCALPSNVNLLAIALVHQ--------- +-----------------------------------------------------------------------------------------------TAPAHALFIASIHAAIPSAGRHGALSRQLGIALDAGQKLLTVGNGAWLAAQS-------GRLNGRKASL-------------------PWFYIAGFERDEVGLSL-----GQDLSDDGPWISCALPQSVNLLAVALVRH--------- +-----------------------------------------------------------------------------------------------EGPAQAVFVSALHCPIPSVAAHPALVRRITTAFDQGLAVCTLGSAAWFAAAG-------GRCQGRLVAL-------------------PWYFMGGFGLDGIELAE-----GQPFVDDRPWLSASHPEALAPMAVALTRH--------- +-----------------------------------------------------------------------------------------------EGPVHAVFASALHCPIPSVAAHPDFTQRIATAFDQGLTVCTLGSGAWFAAAS-------GRCEGRRVAL-------------------PWYFMGGFGLDGIELAE-----GQPFVDDRPWLSASHAEALVPLALALTRH--------- +--------------------------------------------------------------------------------------ATHTFADC-PRNGNVLFVPGGLAGTTQMMEDSDMLSFLREIAGKVDYTTSVCTGGLILGAA-------GLLKARRATTH-------------------WYVHDILPLLGAIPI------EARVVEDGNLITGGA----------------------- +------------------------------------------------------------------------------------------------------------------------MVAQDLVAENARFVVSVCTGSLLLAAT-------GLLVGKKASTHWSLRVT-----------------NVLDLLE-VKVQ-----NKRITLDGKYLTCAGVTSGIDLGLTIVS---------- +---------------------------------------------------------------------------------------------------------------TQIALDEAFVAEVRRLGRGARYVTSVCTGSLILGAA-------GLLQGKRAACHWAWRE-------------------LLSEFGASVD------EGRVVRDGNIFTGGGVTAGIDFALTMVA---------- +--------------------------------------------------------------------------------------------------------------------MTRRSNF-LRIAARARYVTSVCTGSLLLGAA-------GLLNGYKATGYWMVRD-------------------MLPLFGAEFV------HQRVVVDRTRVTGAGVTAGIDFALALTA---------- +---------------------------------------------------------------------------------------------------------------NALLEDQPVLDFVRQRAGQARYVTSVCSGALVLGAA-------GLLKGKRATTHWYAHD-------------------FLEEFGAVSV------DARIVEDGNLITAGGVTSGIDFGLALVA---------- +----------------------STGLEPKEVHSPWQYLTNHGFFIEFATWDGKPAKADSTLEHTLWGKWKISLDEWLKPHAWAPLSNTQPLKPFEFENYDLILIPGGWASREHLEHDTILHEKLSRYCLNCKALAVIGDGISPLLHVKDPLTQEPILKNLTSTGP------------------------------------------------------------------------------ +-----------------------NGSEEMEIIMLVDILRRANLNVVLASVDESTNI-----V-----GSQ-------------RLNADKCILGASDSKYDIIIIPGGPAGAERLHRSTTLQRLLKEQKQESRMYGGIGYSPLILQK-------QGLLQDKTATAHPSIVNQ----------------------LTCQVID-----RSKVVIDGNLITGKGLGTTMDFSLAI------------ +-----------------------------------------------------------------------------------------------IDECDYVAVVGGLLAQ-YRHSQQALIDLIKRADKRGKAVVGLCTAAFLLAEA-------GVLEDRNCCVSWFHRDDFLEL---F----D----------GYTADT-----TSLFHLSGRHYTCAGGLGAAALALSIIQ---------- +------------------------------------------------------------------------------------------------------------------------------MAEASATLVGICTGAFALMRA-------GTMNGHRICVSWFHYWDFVER---F----P----------GADIVA-----DRLFVIDRRRITCSGGRASIDVAAAILL---------- +---------------------------------------------------------------------------------------------------------------D---R----ALAALARVRPGTRLVSICTGAFLLAAA-------GLLDGRRATTHWALTDHFREL---F----P----------RVELDA-----DVLFVDHGDVLTSAGAASGVDVCLHLVR---------- +---------------------------------------------------------------------------------------------------------------------------------------AISTGAFALAAT-------GLLDGRRATTHWHYTRALAAR---H----P----------LVQVDE-----NVLFVDEGTVLTSAGAASGIDLCLHILR---------- +--------------------------------------------------------------------------------------------------------------------------------------MGLCLGTYVLAYA-------GLLEGRRASTHWEFEQDFMGR---F----P----------AVRLDT-----NALYVDDEGLITSAGTAAGLDYCLYLVR---------- +-------------------------------------------------------------------------------------------------------------------------------------MVGLCLGAFVLAEA-------GILDGKTASTHWVWANDFAKK---Y----P----------KVNFDN-----DVLYIDEGNVFTSAGAAAAIDCCLHLLR---------- +-----------------------------------------------------------------------------------------------------------------------------KKKKKKKKKKKKKKKKKKKKAT-------GLLDGRRATTHWHYTRTLAAR---H----P----------RVRVDE-----NVLFVDEGTVLTSAGAASGIDLCLHILR---------- +-----------------------------------------------------------------------------------------------------------------------VLDAVRRAHARGARLLGFCSGAFTLAEA-------GVLDGRRATAHWQWADEFRTR---F----P----------SVRLEP-----DVLFVDDGDILTAAGSAAALDLGLHVVR---------- +---------------------------------------------------------------------------------------------------------------------PEALRAVRAAADAGSIILTVCSGAFLAGAA-------GLLDGRPCTTHWMHADDLARR---Y----P----------TARVDR-----NVLFVDDGNLITSAGTAAGIDACLHLVR---------- +-----------------------------------------------------------------------------------------------------------------------VLDALAAAHDRGALVAAHCVGTFALAAA-------GLLDGRRATTHWRFAGLLARS---H----P----------EVTVEP-----EALYLDDGRITTGAGAAAGFDLCLHLIR---------- +----------------------------------------------------------------------------------------------------LDTA-------SSRPSRRRFGPQVRAAARRADSLIGLDMGAWVMAAA-------GLLHGRRATVHWYELDAFAEA---F----L----------EVDVVA------DSYVVDRDRQSAGSATSAMSLALDLIR---------- +-------------------------------------------------------------------------------------------------------MCGTDYDA----SIEPLLAKLRAAVDRGALVASLCTGAFVLGKA-------GLLDGRPCTTHWRHSASLAAK---Y----P----------LAQVDP-----NVLYVDAGNVLTSAGTAAGIDLCLHIVR---------- +-----------------------------------------------------------------------------------------------------MIVPGWRGVES---VPQRLIEQLQAAHARGARICSICTGAFVLAAA-------GLLDGHKVTTHWRYTDLLATM---Y----P----------GLTIQP-----NELYVDQGTIVTAAGSAAGLDMMLHLVR---------- +----------------------------------------------------------------------------------------------------MIVVPSWPEDLP---LDASLRQILIDGHDRGAVIVGLCLGAIPVADA-------GLLSGRSAVTHWAAMDALRKR---H----N----------DIPLDS-----LVLYVDHGDVLTSAGTASAIDACLHLVR---------- +---------------------------------------------------------------------------------------------------------------------MSARRRRCYGEARGAEVVGLCLGAYVLAYS-------GLLNNRRASTHWEVEHDFAAR---F----P----------TVKLDR-----NALYTRDERLITSAGTAAGIDCCLNIVR---------- +-----------------------------------------------------------------------------------------------LEHADIVIVPGWHDIAT---PSPELMNAVYHAYRRGALVVGLCYGTYVLAYT-------GILEGKQASTHWMAESDFKQR---F----P----------KIILDN-----NALYVEDGNIITSAGSAASLDCCLYIVR---------- +------------------------------------------------------------------------------------------------EADLVVVPAGDSYVHR---YPPELLDALRRATDRGARVLSVCSGVFVLGAA-------GLLDGRPCAVHWKHAEELARQ---Y----P----------RAVVEP-----DVLYVDADPVITSAGTAAGIDACLHIVR---------- +------------------------------------------------------------------------------------------------------------------------MDALRAAHTRGAWVMSICSGAYALARA-------GLLDGRRCTTHWHYSQDLASR---Y----P----------QIHVDE-----NVLYVQDGTIITSAGTAAGIDACLHLVR---------- +-----------------------------------------------------------------------------------------------------MIVPGWLPVDE---PSRAVVRALRRAHARGVRVAGICSGAFALAYA-------GLLDGRRATTHWALTGELAAR---F----P----------RVHVDR-----YVLYVDHGDVATSAGAGAGLDLCFHLVR---------- +-----------------------------------------------------------------------------------------------LQDAQTIVVPGWRGIDA---IPAALGDALAAAHARGCRIISICSGVFVLAAA-------GLLNGRKATTHWRYTENLRQR---Y----P----------LIDVVA-----DVLYVGSDGIMTSAGSAAGIDLCLHLVR---------- +-----------------------------------------------------------------------------------------------LDQADTIVVPGWRGVDT---VPEGLLLALRRAHARGARLVSICSGVFVLAAT-------GLLDGRRATTHWHHTEHLARK---Y----P----------NILVQP-----DVLYTEDEGLLTSAGSAAGLDLCLYVVR---------- +-------------------------------------------------------------------------------------------------------------------------------------MASACAGAFVLAAS-------GVIEERRVTTHWALASLFEKK---Y----P----------NIKVDS-----EQILISHGDIVTSAGVMAWLDLGLEMVS---------- +-------------------------------------------------------------------------------------------------------------------------------------MASACAGAFVLAAS-------GVIEERRVTTHWALASLFEKK---Y----P----------SIKVDS-----EQILISHGDVVTSAGVMAWLDLGLEMVS---------- +-----------------------------------------------------------------------------------------------------------------------MAAWLRRVVGLDTTVISICSGALLAGEA-------GLFDGRSCTTHSDCIETLRRV---A----P----------LSQVAE-----NRLFVEDGNRFSSAGISTGIDLMLHVVS---------- +------------------------------------------------------------------------------------------------------------------------------HHAAGGTVASVCSGAGALGEA-------GLLDGRRCTTHHELQDELAAR---H----P----------RATVVR-----DVLYTTDDRVVTSAGIASGIDLALHLLA---------- +-----------------------------------------------------------------------------------------------PGTVDLPLGPAGDSAAA-ARQEAEIVAWLARQVRPEHRLVSICSGALLAARA-------GLLDGHDCTTHHSAIPALARL---A----P----------AARVLE-----NRLFVESGTRLTTAGITAGMDLMLHLVA---------- +-----------------------------------------------------------------------------------------------------MIISGGMGIDT-VCCDCQILDWLTHIHFSTRRTASVCSGASLLASA-------KLLDGKQATSHWHRLKEFKEK---Y----P----------KVDWKD-----DAIFVRSDKIWTSAGITSGIDMALAMIE---------- +-------------------------------------------------------------------------------------------------------------------------MWSPSAPGPSCSPRPACWPDVA--------------------PRRTGHIALARR---F----P----------DIQVDA-----EPIYVRDGNIAASAGVTAGIDLALALVE---------- +------------------------------------------------------------------------------------------------------------------------------MAATTRRLASICTGSFVLAQA-------GLLSGRRATTHWHETRRLARA---F----R----------DVTVEP-----DAIFVRDVDVYTSAGVSSGIDLALALVE---------- +------------------------------------------------------------------------------------------------------------------------MDWVRKHAAKCRRVASVCTGAFLLAAS-------GWLDGRRVVTHWTRCEQLAQQ---H----P----------KLQVEA-----NPIFINDGPVWTSAGVTAGIDLALAMVE---------- +---------------------------------------------------------------------------------------------------------EPAVRQA--IVEHRIGAWLEAAAPNIRRVASVCSGAFALAAA-------GLLDGREATTHWRWCDQLQAL---R----P----------QTRVQR-----ERIYVRDGPVWTSAGVTTGIELALALVE---------- +------------------------------------------------------------------------------------------------------------GVYA-AAREPHLVQWVAQQAGRSRRVASVCTGAFLLAAS-------GWLDGRRVVTHWTRCEQLARE---Y----P----------QLQVEA-----NPIFINDGAVWTSAGVTAGIDLALALVE---------- +-----------------------------------------------------------------------------------------------AESYDLLLVVGGPGAYS--GSHPNLCTWLRDMEGRVGRLVSVCTGAFLLGEA-------GLLDGHRVTTHWNYTEQLAQA---Y----P----------KAKVEQ-----NQIFINDKSVISCGGITAGIDLALSLIE---------- +-------------------------------------------------------------------------------------------------------------LAA-GPVDDELLSAAGALAERATRVASVCTGAFVLAAL-------GLLDGRRATTHWRHVRTLARL---H----P----------RVRVEP-----DALHVRDGRYLTSAGISAGIDLTLALVE---------- +-----------------------------------------------------------------------------------------------GDPVDTVILPGGAGVDA-ARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEA-------GLLGRTPSDDALGLCRTFRPR---I----S----------GLRVDA-----DPIFMRSSQVWTAAGVTAGIDLALALVE---------- +-----------------------------------------------------------------------------------------------GDPVDTVILPGGAGVDA-ARSEPALIDWVKAVSGTARRVVTVCTGAFLAAEA-------GLLGRTPSDDALGLCRTFRPR---I----S----------GRSGRC-----RPDFAEGVDGWSHRRHRPRAGTGRRRRD---------- +---------------------------------------------------------------------------------------------------------------MVTHYDGDTLQALKMWHTNGTTLAANCASVFWLAHA-------GLLDQRAVTTHWKLCEQLAQE---F----P----------LIEVKR-----HEMVVDEGSIITGSGLFAFQDLTLHVIA---------- +--------------------------------------------------------------------------------------------------MNHSR-----QFKS-MGPDPRLVAWLAENGPRSRRVCSVCVGAFLLAEA-------GLLAGRSATTHWGFIETLKRK---C----D----------GATILD-----GPIFVHDGNIWSSAGVSAGIDLALHLVE---------- +-----------------------------------------------------------------------------------------------------------------------------------RACGGVEAGTWLVARA-------GLLEGRSATTHWEDMEDFSSA---F----P----------GVDVRP------DRYVIDGPVFTTGGASPTFDLMLHLIR---------- +-------------------------------------------------------------------------------------------------------------ARN-FHAPPALVNWIVRRAPRVRRICSVCTGAFLLAAA-------GQLQGKRAATHWEWVDRLREL---H----P----------QVDVDA-----DKIFINDGAIWTSAGVSAGIDLTLALIE---------- +-------------------------------------------------------------------------------------------------------MSGGSGAFD-IDADGAPAQWLRDVAAGGTRILSVCTGAFLAARI-------SLLDGCTATTHWAYADRLATE---F----P----------LVTVDA-----DWIFVQSTSVWTSAGVSAGIDLSLAAIE---------- +-----------------------------------------------------------------------------------------------ADPGNPARLAGVLSPVD-EPASPGVIHFLQATARQTRRIAGICTGAFVLAQA-------GLLEQKRATTHWAHSHSLASR---H----P----------TIQLED-----DRIFIIDDTIWTSAGMTAGLDMALGMVE---------- +--------------------------------------------------------------------------------------------------------------------MASTIDFVRRAAAQARRIAGAGMGAFLLAEA-------GLLDGRRATTHWLRARELAER---F----P----------MIKVEE-----DRIFIADGPVWTSAGMSAGIDLSLALIE---------- +--------------------------------------------------------------------------------------------------MDVLILIAMPGVEILDEESEHSKPLIALAQQQDAIIAAHCGACYLLANS-------GLLDGKRATISWWLKAEASRR---F----P----------QVRWDA-----SRLLIRQDRLYTCGGGFSGLELARALLI---------- +-----------------------------------------------------------------------------------------------LREVDVLVVPGFELRPG--ARLAPEIAAIRARAAAGTALVSLCVGAFLLAEA-------GLLDGRRATTSWLHAGELARR---H----P----------EADVRP-----EHLVVTDRGVTTTAAFSAMYDFALDLVR---------- +----------------------------------------------------------------------------------------------------MVIVPGLAWMDEQRRDAETARKALRAAFRSGAEIASSCSAVFLVASA-------GLLDGRRATTTWWLGPLFRQL---F----P----------RVTLDT-----DAMVLTDRRMATAGAAMAQLDLMLSIIA---------- +-----------------------------------------------------------------------------------------------FRSADIMLVFGPA--AD-HPVSKQLGGDLRAAWRRGARIGAVGTAVQLLANA-------GILAEREFTLHWQSRASFLES---H----W----------HLC-PS-----DHRFCIDQRILTCGGGISASDLILQVIE---------- +-----------------------------------------------------------------------------------------------LADTDTDIVSGGRGHRA-ATGNTALIRHLRRLAQQTTRIGSVCTGATVLAET-------GLLHGRRTTTHWRYADELAVR---Y----P----------AVTVDA-----APIFIRDGPIATSGGVTASLDLTLAYIE---------- +-----------------------------------------------------------------------------------------------LLNMDIVFICGGFQLYK--NMTVRLKNFLYRLDQQKIALGGLCTGAYVLAKA-------NLLNGFRASLHWENSLAAQEE---F----P----------LVQ-FT-----PHIFTIDANRFTCSGGLAAIDLGLALVE---------- +-----------------------------------------------------------------------------------------------LFEMDIVFICGGFQLFK--LNNPLHKIFLKRLDQANIALGGICTGAYVLASA-------DLLNGYQASLHWENSLAAQEE---F----P----------QVN-FN-----PHIFSLDRNRFTCSGGLASIDMCSQLVE---------- +------------------------------------------------------------------------------------------------KELDLLVVCGGYRTELIDP---SLTALLRTASECDVILAGLWNGAWFLGAA-------GLLDGYRCAIHPEHRSALAEI---S----R----------ITHVTS------EAYVLDRNRMTASSPVGAFQMVLEWIK---------- +-----------------------------------------------------------------------------------------------------MLYAAAFELPACLV---GYRHYLKKISKLPIALGGLWNGAWYLGAA-------GLLDGYRCAIHAEQRTALAER---A----P----------YALVSQ------EPLELDRNRMTSATPSGAFDMMIRWLG---------- +-----------------------------------------------------------------------------------------------LASFDYLVVFGGRNALA-AALAPRYRALLRQAGKAGVKLVAVDNGAFLLAAC-------GLLQGHKVVVHWRHEAEFRAA---F----P----------HLQVLS-----EQLYCIDGSRITCAGGTAAIDLAVALLS---------- +-----------------------------------------------------------------------------------------------------MVFFGSRTASE-QQQAAYYRSFVRNVVANGIPIVSIDNACFTLAEL-------GLLNRHQTVVHWRHHSEFKAT---Y----P----------KVIVRD-----EQLYHFDKKLISCTGGSATIDLAVAILQ---------- +-----------------------------------------------------------------------------------------------LADYDYLVLFGSRNAEA-ASLAPHYNSLLKRATRAGVKLVGIDNAAFLMAAC-------GLLDGHKVVVHWRHEAEFRAS---F----P----------HLNVLR-----EQLYCIDRGRITCAGGTAAIDLAVELLS---------- +-----------------------------------------------------------------------------------------------LTRVDYVVLFGSRTAKE-QQQANLYRSFLKKSMAMGVPIVSVDNACFTLAEL-------GLLNGHQVVVHWRHHNEFRTD---Y----P----------QVTVRE-----EQLYHFDGKVISCTGGSATVDLAVAILQ---------- +-----------------------------------------------------------------------------------------------WREFDYLVLFGGRNATA-AVLAPAYRALLRCAVKAGVKLVCVDNAAFLLAAC-------GLLDGFKVVVHWRHEAEFRAS---F----P----------GVQVLT-----EQLYCFDGPRITCAGGTAAIDLAVELIA---------- +-----------------------------------------------------------------------------------------------LADFDYLVLFGGRNAQA-AALAPAYQSLLRRAARAGVKLVAIDNASFLLAAC-------GLLDGHRVAVHWRHEVEFRAS---F----P----------HLRLAR-----ERLYCLDGARISCAGGTAAIDLAVELLA---------- +-----------------------------------------------------------------------------------------------WSAYQYLVIFGARETGA-AALATHYRAILRQANQHGLSLVSIDNACFLLAQA-------GFLKNHRVAVHWRHAREFAIL---F----P----------NISMST-----EQLYLLDGKRISCAGGSAAIDLATELLS---------- +-----------------------------------------------------------------------------------------------SRRHALQVTCAEDPAELTAPVEQLVRPQAALI----NQLKQSPGQAWLCAEA-------GVATDTPLCAHWQLIDSLRIR---Y----P----------AQRFCT------HLYNCESRWMSAAGGLATVDALLHWFS---------- +----------------------FPAFQALDVFGPLDALLSRSYDMYTIADTLDPV----STKPDTA--R---QPATTNSDFGQRIVPTHTFKTA--PPLDVLIVPGGQGTR-YPGIST-VVEFVGERFDSLQYLLTVCTGSGVAARA-------GVLDGRRATTNKLSWKETIAL-----------------RPEVDWVH-----KARWVQDGHVWTSSGISA-------------------- +----------------------FPAFQALDVFGPLDALLSRSYHMYTIADTLDPV----STKQDTT--H---QPSTTDSDFGQRIVPTHTFKTA--PPLDVLIVPGGQGTR-YPSVST-AIDFVRQRSDSLQYLLTVCTGSGVAARA-------GVLDGRRATTNKLSWKETIAL-----------------RPEVEWVH-----KARWVRDGHIWTSSGISA-------------------- +----------------------YNGTALLDYVGIGMYLLSMHVSVDMIAETSGVI----YSAPG--------------------VYASTSFRAT--SPVDILVVPGGPGRT-SVIQNQAFMDYVSAAAKSAKYVLVVCTGAEIVART-------GFLDGKNATTNKLAFDAIAAT-----------------RPAVNWIR-----KARWVVDGKTWTSSGVSA-------------------- +----------------------FPAFQALDVFGPLDALISMNYSIHIISSTLDPV----STKPR--S-A---MI--GNSNFSEAIVPTHNFTHP--PKLDVLFVPGGIGTR-APELDA-HIAFIRETYPSLQYIVSVCTGSWLLARA-------GVLDGKNATSNKRAWAGTAGL-----------------GNGTNWIT-----HARWVQDGNIWTSSGISA-------------------- +----------------------FPGFQALDVFGPLDALLSRSYPLSLISSTLDPV----STQPPASVIV---GPPAAVSNFSQSLVPTHTIDAP--PSLDVLLVPGGLGTR-APGLEP-LIDYIGRTAKETKYVLTVCTGSWLAARA-------GALDGKNATSNKRAWAGREGL-----------------GNNVNWIK-----HARWVQDGDTWTSSGVSA-------------------- +----------------------FPSFQALDVFGPLDALLSMQYPLYLISSTLDPV----STKAR--S-A---GMNTHNSNFSEAIAPTHTIQDA--PALDVLMIPGGLGTR-ADDLDP-LIAYIADAAQETDYVLTICTGSWLAARA-------GVLDGKNATSNKRSWAGREGL-----------------GNGTNWIA-----HARWVEDGNVWTSSGISA-------------------- +----------------------FPAFEALDVFGPLDALLASDYPMHIISSTLDPV----STKPR--S-P---AMNTHNSNFSQAIVPTHNFTHP--PKLDVLFVPGGMGTR-APELDA-HIAFIRETYPSLQYIVSVCTGSWLLARA-------GVLDGKNATSNKRAWAGTAGL-----------------GNGTNWIT-----HARWVQDGNIWTSSGVSA-------------------- +----------------------YPGYQALDAWGPLDFLLSFRTQLTIISPLPVPI----RTS----N-P---AFTRSNSTVDEVVLATHSFANA--PPLDVLFVPGGVGNR-DVAIQS-SIDFVRATYPSLQYLITVCTGAGIAARA-------GVLDGRNATTNKRAFYEMANH-----------------GPRTWWHS-----KARWVVDGNVWSSSGVSA-------------------- +----------------------SRAYEVLDIFGPLSALLARMHQMYMIAESMDPV----TVEPV--S-P---AMNTKNSSFFPLVLPTHTYATA--PDLEVLIVPGGLWTR-SPNLNS-TIAYIRTVYPSLRYLVSICTGAGVVARA-------GVLDGRRATTNKASWASTIVH-----------------GPRTEWVA-----RARWVVDGNVWTSSGVSA-------------------- +----------------------FPGFQPLDVIAPADVMLSGSVNMSFIWKEAGPV----WARSPPRLAP---PNPGVFPIQAPSFVATHSFADA--PPLDVVLVPGGAGSR-VLHNDTSVEDFVKERYPTLRYLLSVCTGSGFLAKS-------GLLDGRRATTNKAAWSWPTQF-----------------GTNVTWVP-----TARWVEDGNIWSSSGVSA-------------------- +----------------------YPGFQPLDVIGPSDIMLSASVNMSFIWKEAGPV----WARSPD----------TQLPIQAPSFMATHSFADA--PPLDILLIPGGGGSR-YLINDTAIEDFARERYPSLKYLLSVCTGSAFLAKA-------GLLDGRKATTNKAAWSFPTEF-----------------GNNVTWVP-----TARWVVDGNVWSSSGVSA-------------------- +----------------------FPGFEPLDVFGPLEMIMSYYMNMATIAETVGPV----SARPPLHYAP---NEPDLSYMINPQVVATHTFETA--PELDILLVPGGTGNV-ALKNDTKVEDFVRERYPELEYLLSVCTGAITLARS-------GVLEGRRATSNKGAWAQTATH-----------------GKNVTWVP-----SARWVVDGNVWTSSGVAA-------------------- +----------------------------------------------------------------------------------------------DAQVYDALLVPGGSGAAEAIKN----LRLMNWFGRAAKVVAAIGTGTLILAAS-------GILGDRRVA-YTSELDET------Y----------------HQVRSS--P-GEEVIRDGNIITTGSSEFGVELGKAII----------- +-----------------------NGSEEMEIIMLVDILRRANMNVVLASVDESTNI-----V-----GSQ-------------RLNADKCILGASDSKYDLIIIPGGPAGAERLHRSTTLQRLLKEQKQESRMYGGIGYSPLILQK-------QGLLQDKTATAHPSIVNQ----------------------LTCQVID-----RSKVVIDGNLITGKGLGTTMDFSLA------------- +------------------------------------------------------------------------------------------------ERYAALILPGGRGALAVAHRYPSLLRLIQAFHERGRIIAAISTAPVLLSAAGLTVTGE---LGVSLTAHPLVKDDIYPPSAYL-QRID-WEPDELEQQGAARNE---PPASVAVADANVVTAACWQG-------------------- +---------------------LANGFEEIEGLAPVDILRRGGVDIKTVSVTGTE-----WVETS--------------HG--VTIKADLKFEDISFEDADMLMIPGGMPGSTNLNEHEGVRQALIAQHKAGKRIGAICAAPMVLAS------------------------------------------------------------------------------------------------- +--SKNILVVLP-----------RRGLWYGDFGPLADQLRKEGYTVTVASTAAGQAE---LLEGSE--GS--------------AVDIDLVLKDVDTTNYGAIVVAGFNASMCDGADAKLVKGLLEKMNRESKPLVGICGGQRVLAYH-------GWLEGRTVAHSPIAAQD--------PKY---------NACGANFDH-----DLAVKVDGSILTARDDKAAAELGKRLAGY--------- +------------------------------------------------------------------------------------------------PHVDCVLVTGIDP-LSSLLGCTKF--VKKGWADPKVLFLTVCTGSLFLAQT-------GVQNGHQVASNTMALK-------------------MVVDRAVHWVG-----DARWVKDGRVWSAAGITAGIDLA--------------- +------------------------------------------------------------------------------------------------AGHDIVLIPGGMG-TRSLVDDRSFLTRLRGWATPASIISSVCTGSALLAAA-------GLLEGYRATSNKMAYA-------------------WASSRDVRWEP-----RARWVHDRDRWTSSGVAAGMDMT--------------- +------------------------------------------------------------------------------------------------EHIDILVISGGSP-GRLMKEHEAFMTFLKGVAETATYVLTRRG------------------------------------------------------SDDQWVH-----KARWVQDGTIWTSSGVTAGMDMA--------------- +------------------------------------------------------------------------------------------------EHIDILVIPGGSP-GRLVMQHDAFMKFLKRVTEGATYVLTAH-------------------------------------------------------PTVNWVH-----KARWVRDGYIWTSSGVTAGMDMA--------------- +--------------------------------------------------------------------------------------------------------PGGRG-TRPLAGDGEFLAALRELADASTYCLSVCTGSALLAGC-------GALNGREATSNKRALD-------------------WVTSEKVLWRG-----QARWVADGKFYTSSGVSAGMDMA--------------- +--------------------------------------------------------------------------------------------------------NLGDN-SRPGEPSKALTEFVEGQAPGARYVLSVCTGSWILAAL-------GLLDGRRATTNKLLFN-------------------EIKRPAIQWVA-----KARWVVDGKFWTSSGVTAGQDMG--------------- +-------------------------------------------------------------------------------------------------------------------MPQSVVEFVRAQVPRAQYVLTVCTGGWLLAAL-------GLLDGKRATSNKFFFN-------------------EIKKPTVQWIA-----KARWVVDGKFWTASGVSAAQDMA--------------- +------------------------------------------------------------------------------------------------------------------------E-FLRTQAPSARYVLSVCTGAWILAQA-------GLLDGKRATTNKSLYD-------------------VVVSTSIRWVH-----KARWVVDGKLWTASGVTAGLDMA--------------- +-----------------------------------------------------------------------------------------------------MLIPGGQG-TRQLVKDMPFLTWLTQLVDEAEFCLSVCTGSALLAAT-------KQLDGKWATSNKLAFE-------------------WVRQPDVKWKA-----VARWVRDGKFYSSSGVTAGMDMT--------------- +------------------------------------------------------------------------------------------------DPKGVLLIHGGSG-TRALVGNDCWIGQLASLATRSPQVMTVCTGSALLAAT-------GVLDGRRATSNDLAFD-------------------WVVSERVDWIR-----DARWVVDGRFRTSSGISADIDMA--------------- +------------------------------------------------------------------------------------------------ANEGILIIPGGKG-TRKLVKDSEWIKKLKHLSLSAPNVLTICTGDALLAKI-------ELLNDKKATSNKRAFD-------------------WVKSKSVFWQE-----KARWVVSGKYYTSSGVSAGIDIA--------------- +------------------------------------------------------------------------------------------------PDSSVLFIPWGMG-TRLLVNDKVFIRLLTQTIPQASYCLTVCTGSALIAKT-------GLLDGKKATSNKKAWS-------------------WVTSSEVDWQH-----CARWCVEDGLYTSSGVSAGIDMA--------------- +------------------------------------------------------------------------------------------------HSFDTLFIPGGFG-MMPLVWDLMLLQQIGQLVDRAPNVFTVCTGSILLSAT-------GRLDGRQATTNKRLYD-------------------EVTPPGVKWQK-----RARWVHDGKFLTSSGVTAGIDAG--------------- +------------------------------------------------------------------------------------------------DVTGILLIPGGQG-TRPLVNNDDFIRKLGDAANLSTYCLTVCTGSALLART-------SLLNGRKATSNKLAFE-------------------WVKSPSVQWME-----HARWVNDGKYYTSSGVSAGIDMT--------------- +------------------------------------------------------------------------------------------------DCSGVLLVPGGEG-TRYLINDNMFIEKLSDIALQSQYCLTVCTGSALLAKA-------NMLNGFKATSNKRAFD-------------------WVQSSEVEWIS-----HARWVVDGKFYTSSGVSAGIDMA--------------- +------------------------------------------------------------------------------------------------DYSGILLLPGGQG-TRCLVDDAAFIRTLTGISQQAMYCLAVCTGSALLAKT-------GLLDNRKATSNKKAFA-------------------WVKSGNVTWIE-----KARWVVDEKYYTSSGISAGIDMT--------------- +----------------------FTGFQALDVFGPLDIFNILRINLHIIAPTLEPVHYPPWNPG------V-------GSRWSESVNPTHTLSDP-PKDLDVLFVPGGAGTDANIAEVTQIIDYVRDVYPSLQHILSICTGAGILARA-------GVLDGRNATTNKRA--------------------------------------------------------------------------- +--PPRILILCPDKA--LA---------PYSASEPWYIFKQAGCVIEFATENGDVPKDQRMLERDFIGEHIERFYAMAGS---DEYLSPRKWSDPSLLVYDAVYLTTGFDTMRQFVESESLHKLMASYFPLSK--------------------------------------------------------------------------------------------------------------- +--PPRILILCPDKA--LD---------PYTASESWFTFKEAGCVIEFATENGDIPKDQRLLERDLMNDAVEKFFAMAGS---DEYLNPRAWSAPDLLQYDAVYMTTGFDTLRQFVESESLHRLLAAYFPLTK--------------------------------------------------------------------------------------------------------------- +--PPRVLILCPDKT--LA---------PMAAAEPWYIFKEAGCVIEFATENGDVPKDQRMLERDIMGDDIEKFYMMAGS---DEYLNPRAWSNASLLPYDAIYITTGFDAMRQFVESESLHKLLASYFPLTK--------------------------------------------------------------------------------------------------------------- +----------------------------------------------------------------------------------------ISLDECTLESQDLIILPGGNT--WGEDIHQPILKKVGDALKLGTTIAAICGATLGLANE-------GYLNSRKHTS--NDLEYMK---MVCP-----------NYKGETLYE-----KGPAVSDENLVTASGIA--------------------- +-------------------------------------------------------------------------------------------------------MPGGTT--WSEEIHQPMLEKIGQALKLGTIVAAICGATDALANM-------GYLDNRKHTS--NNLEYTK---MVCP-----------NYKGEKFYE-----LGSAVSDANLVTASGIA--------------------- +--------------------------------------------------------------------------------------------------MYLILCQIGNT--WSENIHEPILKKVGEALKLGTIIAAICGATEGLANF-------GCLDSRKHTS--NSLEYIK---MVCP-----------NYKGEKFYE-----MGPVASGENLITALGVA--------------------- +----------------------------------------------------------------------------------------LSVDECILQSTDVLVLPGGNT--WTEAIHEPILKKASTSLKEGAVVAAICGATMGLAKM-------GLLDSRRHTS--NNLEYMK---MICP-----------HYIGESYYE-----MEPAVTDGNLVTASGIA--------------------- +----------------------------------------------------------------------------------------LSIEAIELDDVDLLIVCGGTA--WQSGQAPDITALVAEAHRKNIVVAGICDGTRVLAQS-------GVLDNLRHTS--NSAENLS-----QL-----------NYAGAAYYQ-----DVPAVADQRVVTAPGTA--------------------- +---------------------------------------------------------------------------------------------------------------------------IRQAMEPNVKIGVICHGLWLLCAA-------DVLDNRRVTCAHNILV-------------------DVENAGADIIYE-NDIAADIVIDENLVTGRHPDLVNKFMETLVR---------- +------------------------------------------------------------------------------------LTPTRAFADCP--PADILFVPGGPGQL-ALMQDTDTLAFLRAQAQGARWITSVCTGSLVLAAA-------GLLTGYRATCHWMSIDQ-------------------LAMFGCTPV------SERVVLDGNRLTGAGVTSGIDFALTLG----------- +----------------------------QDLVGPQTIFKILGAEIHLVGMTMTPVSTDVGIP----------------------VPPTNTPATC-PQELDVLFVPGGLGT-IACMNDPDVLAFLTSRAPHSRYITSVCTGSLILAAA-------GLLEGYKATSHWGVVN-----------L--------LPLMGAIES------HERVVQDRNRITGGGVTAGIDFGL-------------- +----------------------------LDLVAPQSVLQMLNSEIHLVGETREPVATDLGLP----------------------VTPTCTINEC-PRDLDVLFVPGGLGS-VACMKNPAILDFLADRGAHARYVTSVCTGGLVLGAA-------GLLRGYEATAHWAVTH-----------L--------LPLMGATKV------DARVVHDRNRLTGAGVTAGLDFGL-------------- +------------------------GTEEMEAVILADVLRRAGAEVTVASVEQQLEV------EAY-GG-------------T-RLVADTFISTCSTEIFDLVALPGGMPGSARLRDCEVLQKITSRQAEEKRLYGAICAAPAVTLLP------WGLLKRKQTTCHPAFIDKISS---------------------FRVVK------TNTRVSGELTTSRGPGTSFEFAIC------------- +---------------------------------------------------------------------------------------------------------GGMPGSVNLRECKVLERMVKMHAEKGELYGAICAAPAVTLAH------WGMLKGLKATCYPSFMEKFT----------------------AEVI----PVNSRVVVDRNVVTSQGPGTAIEFALALVEQ--------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASVDESTNV-----V-----GSQRM-----------KIVADKCILGASDSKHDLIIIPGGPAGAERLHRSTTLKKLLKEQKQAGRMYGGISYSPLILQK-------QGLLEDKTVTAHPSIVDQL----------------------TCQVID-----GSKVVIDGNLITGKGLGTVMDFSLA------------- +------------------------------------------------------------------------------------------------------VTVGGNT--WNN-DYKKLLHLIKTAFQNNIPVGAICGAVDYLAKN-------GFLNHYNHTGNSV--D-------------AW------KG-YENYHAKSSFFQQQAVTDKNLVTANGTA--------------------- +------------------------------------------------------------------------------------------------------VMIGGDS--WSN-DNKKLLHFVKTAFQKNIPIAAICGAVDFLAKN-------GLLNNHSHTGNFV--Y-------------LW------KD-YKQYKPISSFVEKQAVRDKNLVTANGTA--------------------- +---------------------------------------------------------------------------------------------------------------------MSSLILQSAFLKTGVPVAAICGAVDYLAQS-------GLLQGYKHTGNMQ--F-------------PW------LE-SENYQNKEDFIEQQAVKDHNLITANGTA--------------------- +-------------------------------------------------------------------------------------------------------MIGGNS--WDI-KNHHLYQIIDKLLKTDVPVAAICVAVDYLAQS-------GLLQGYKHTGNAQ--F-------------PW------LE-SENYQNKEDFIEQQAVKDRNLITANGTA--------------------- +------------------------------------------------------------------------------------------------------VLIGGNS--WAV-NNEPLKQLITSRLHTDQPVAAICGTVDYLARN-------GLLNQYQHTGNAQ--Y-------------LW------RD-YRAYQNQNGFLAQQTVWDRNLVTANGTA--------------------- +------------------------------------------------------------------------------------------------------VLIGGNA--WST-ENENLRALVASRLKHNQPVAAICGAVDYLARN-------GLLTGYRHTGNAQ--Y-------------LW------RQ-DKEYVNGQDFVATQVVTDCNLVTANGTA--------------------- +------------------------------------------------------------------------------------------------------ILIGGNS--WQI-KNSVLKQLLQDRLKNNKFVGAICGAVDYLAKN-------GLLTNFKHTGNAQ--Y-------------LW------KD-FDQYQNKSDFLEEQTVRDHNLVTANGTA--------------------- +------------------------------------------------------------------------------------------------------VLIGGNF--WSI-KNEYLRELITKQLRSKRPVAAICGAVDFLAQN-------RLLTRYKHTGNAQ--Y-------------LW------QS-YSNYTNHDDFVETQAVKDLNLVTANGTA--------------------- +---------------------------------------------------------------------------------------------------------------MDS-CHALILGKAKDCLDKGIPVAAICGATMALASA-------GILDTYRHTSNFA--Y-------------LK------KE-CPNYHGEENFQFQSAVTDGDLITASGTA--------------------- +------------------------------------------------------------------------------------------------EAIDVLIVPGGVGTRNDRS--T-EIDFVKEMYPSLKAVLSVCTGATILARA-------GVLDGRRATTNKRAFAWA-------------------TSTGVKWVA-----EARWVVDGNIVTGSGIS--------------------- +------------------------------------------------------------------------------STFWPSFVPTHTYADD-P-DIQVLLVPGGGVA--RSPDLGPEIEYIRKVFPRLEYLITICTGSGIAAQA-------GVLDGHRATTNKRAWAET-------------------VQKGVKWVSP-----ARWVDDGKVWSSSGVTAGIDLA--------------- +------------------------------------------------------------------------------SSFFPTIVPTHTYDDD-P-PLDVLIVPGGAAA--RSPDLGPELVYIRRVFPKLQYLITICTGAGIAAQS-------GVLDGHRATTNKAAWSTI-------------------TPMGVKWVSP-----ARWVEDGKVWTSSGVTAGLDLT--------------- +------------------------------------------------------------------------------SSFWPRIVPTHTFADS-P-ALDVLFVPGGAAA--RSPDLGPEIAYVRDVFPSLRYLITICTGAGIAAQA-------GVLDGHRATTNKAAWDEI-------------------TAMGVKWVSP-----ARWVEDGKVWSSSGVASGIDLT--------------- +------------------------------------------------------------------------------STFWPTISPTHTLTSP-PSNLQVLIIPGGPGA--RSPDLGPEIAFIRSVFPKLQYLITICTGSGIAAQS-------GVLDGRRATTNKAAWNSM-------------------TAMGVKWVAP-----ARWVEDGKVWSSSGVTAGIDLI--------------- +------------------------------------------------------------------------------SNFWPSIQPTATFADD-L-DLDVLIVPGGPGV--RAAGLEPIVEYIKEMYPKVKYLITICTGASLAARA-------GVLDGKRATTNKRAWAQM-------------------TAFGVNWVAP-----ARYVIDGNIWSSSGVTSSLDLT--------------- +------------------------------------------------------------------------------SVFKPEIVGAATFGDD-L-DLDVLLVPGGAAA--RDSTLTYVDDYVAEMFPKVKYLLTICTGAIFAARG-------GVFDGRRATTNKNAWDLV-------------------TQHGVTWVAP-----ARFVQDGKVLSSSGVSAGLDLM--------------- +------------------------------------------------------------------------------SSFWPTIQPTATFYDD-L-DLDVLIVPGGPGI--RAPGLEPIVEYVKRYYPRVKHLITICTGTSFAARA-------GVLDGKSATTNKAAWKLI-------------------TDMGVKWVSP-----ARYVNDGNVWTSSGITSGLDLI--------------- +------------------------------------------------------------------------------SSFWPTIQPTATFDDD-L-DLDVLLIPGGPGI--RAPGLEPIVDYVKRYYPRVKYLISICTGASFAARS-------GVLDGKRATTNKASWKLI-------------------TDMGVKWVSP-----ARYVNDGNVWTSSGVSSGLDLI--------------- +------------------------------------------------------------------------------SSFYPTIAPTATFADD-V-NLDVLIVPGGPGA--RAAGGEDVVEYVKRTYPKVKYLITICTGTAFAARA-------GILDGKRATTNKRAWDVI-------------------RAYGVKWVAP-----ARYVVDGNIWSSSGVTASLDLM--------------- +------------------------------------------------------------------------------SSWWPTFQPTNTFDDD-L-DLDVLIVPGGPGV--RAPGLEPIVEYVRKHAPRVKYLVTICTGASLAARA-------GALDGRRVTTNKAAWGLI-------------------TAQAAKWVSP-----ARYVVDGNVWTSSGVTSGLDLT--------------- +------------------------------------------------------------------------------STVYPTLPPTHTLTTV-PEDLDVLIIPGGLGA--RSPLINATANYIAATYPKLPYLLTVCTGSVLAARA-------GILDGKHATTNKASWDAN-------------------VVYGVEWVPR-----ARWVVDGKVWSSSGISAGIDAT--------------- +------------------------------------------------------------------------------SSFFPKILPTHTYATA-PKDIEVLMVPGGLWT--RSPNLNATISYIKTTYPSLRYLISICTGASVVARA-------GVLDGRRATTNKASWAST-------------------VVHGTEWVAK-----ARWVVDGNVWTSSGVSAGIDAT--------------- +------------------------------------------------------------------------------SNFTASFNPTHTFDNP-PDDIEILLVPGGLGM--RRGNSSPVVDFVRKTYPKVKYLLTTCTGAGVAARA-------GVLDGKRATTNKAAWNEI-------------------VKMGVKWVSP-----ARWTVDGNIWTSSGVSLVASLF--------------- +------------------------------------------------------------------------------SNFTASFNPTHTFDNP-PDDIEILLVPGGLGM--RRGNSSPVVDFVRKTYPKVRYLLTTCTGAGVAARA-------GVLDGKRATTNKAAWNEI-------------------VKMGVKWVSP-----ARWTVDGNIWTSSGVTSGFDLI--------------- +------------------------------------------------------------------------------SRFTVSINPTHTYHKP-PRDIDVLLVPGGMGV--RSGNSSPAVRFIRKAYPAVKYLLTVCTGAGVAAKA-------GVLDGKRATTNKAAWNET-------------------VKMGVRWVSP-----ARWTIDGNVWTSSGVASGLDLI--------------- +------------------------------------------------------------------------------SRFELSINPTHTFANA-PSDIDVLFVPGGGGE--RLGNITAAINFIRATYPKVRYLITVCTGAGVAAQA-------GVLDGKRATTNKWAWGSV-------------------ADEFVKWTSP-----ARWVVDGNVWTASGVLSGVDLI--------------- +------------------------------------------------------------------------------SRFAASINPTHTFEKP-PRDIDVLLVPGGPGM--RHANMSPAINFIRKTYPRVKYLLTVCTGAGLAASA-------GVLDGKRATTNKASWKDI-------------------VAMGVKWVSP-----AKWTIDGNIWTSSGVTSGIDLI--------------- +------------------------------------------------------------------------------SSMWFSLNPTHTYDNP-PKDIDVLLIPGGAGA--TFGNVSRVIDFVREAFPSVKYLLSTCTGAGIAARA-------GVLDGKRATTNKKAWSTI-------------------TGMGVNWVSP-----ARWAVDGNVWTSSGVTSSLDMM--------------- +------------------------------------------------------------------------------STFRFSLNPTHTFASA-PKDLEVLLVPGGPAL--LFGNETETVNFVRKTYPKLKYLLTTCTGAGIAAQA-------GVMNDKRATTNKSAWARI-------------------TSLGVKWVSP-----ARWAVDGNVWSASGVTSALDMI--------------- +------------------------------------------------------------------------------SSFWPTIPPTKTFADD-L-DLDLLIVPGGPGA--RNPNLGAVTDYIAKMAPKVKILMTICTGSGIAARA-------GVLDGHLAATNKNAWATM-------------------KAMGVNWVSP-----ARFVIDGKIWSSSGVTSGLDLI--------------- +------------------------------------------------------------------------------SSFFPTIPPTNTFNDD-L-DLDLLIVPGGPGA--RNPNLQAVTDYIAKMYPKVKMLMTICTGAGVAARS-------GVLDEHLATTNKNAWATM-------------------KEMGVNWVSP-----ARYVIDGKVWSSSGVTSGLDLM--------------- +------------------------------------------------------------------------------SSFFPIVPPTNTFDDD-L-DLDLLIVPGGAGA--RNPSLQAVTSYIAKMYPKVKILMTICTGAGVAARS-------GVLDGHMATTNKNAWATM-------------------KEMGVNWVSP-----ARYVIDGKLWSSSGVTSGLDLI--------------- +------------------------------------------------------------------------------SSFWPTVQPTNTFDDD-L-NLDVLIVPGGPGT--RSTSLQAEIAYIQKMFPKVDILMTVCTGAGIAARA-------GVLDGRMATTNKKAWDTI-------------------KAMGVNWVTP-----ARFVIDGKIWSSSGVTSALDLV--------------- +------------------------------------------------------------------------------SSFFPTVPPTNTFDDE-L-DLDLLIVPGGSGA--RNPNLQAVTSYIAKMFPKVKILMTICTGAGVAARS-------GVLDGHMATTNKNAWATM-------------------KEMGVNWVSP-----ARYVIDGKIWSSSGVTSGLDLI--------------- +------------------------------------------------------------------------------STFWPVFPVTDTFEDE-L-DLDVLIVPGGPGV--RNPSLQAAEEFIKRTYPRVKLMLTVCTGAGLAARA-------GVLDGRLATTNKKAWDTM-------------------TEFGVQWVSP-----ARYVMDGNIWSSSGVTSALDLV--------------- +----------------------ESGYVEAEMAYLERRFAEEGARVDFLTRLWGQ----RSLTFT--GQETRLPF---------TVDDVEAVDDERIAGYDALIVPSGLVARLRYTENVDAVALLRRAFGMRVLKGISCHGMWLAAPI--P----EVVRGRRVTCHNNLVG-------------------DVRNMGAQYTD------QDVVVDDDLVTSRTAEHCHLFARMMID---------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDKVMIDFVKKIDKEATFITSHCDGAFVLAKA-------GLLNNVTSTTFPSDIDK-------MREMFP----------KLDIKK-----EVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PPIDILVIPSAEGHLNTDLKDTTMLSFVKKVATSARLITSHCDGAFVLAEA-------GLLDGVVSTTFPSDIET-------YKKRYP----------QLTVMD-----SVLFVHDDKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDKIMLDFVKQVDKEAQFITSHCDGAFVLAKA-------GLLNNVVSTTFPSDIDK-------MRAMFP----------ILDIRK-----EVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PNIDILVIPSAEHHIDTDLDDVVMLSFVKKVDEKALFMTSHCDGAFVLAKT-------GLLDTVASTTFPGDLLK-------YQEKFP----------QLNVKK-----NSLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDTAMLYFIKKVDEEALYITSHCDGAFVLAKA-------GLLNEAVSTTFPSDIDK-------MRTLFP----------LLDIRK-----DVLFVHDDKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PQIDILVVPSAEHHLDTDLDDKAMIDFVKQVDKSALFMTSHCDGAFVLAKA-------GVLDNAVSTTFPSDIDQ-------MRSTFP----------NLDIRK-----EVLFVHDKKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PDIDILVVPSAEHHLNTDLKDTIMLNFVKKVSKDALFVTSHCDGAFVLAKA-------GLLDEVVSTTFPSDIDT-------YKTMFP----------HLRVKD-----SVLFVHDGKFITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PHIDILVVPSAEHHLDSDLKDNQMLNFIKKVDENALYMTSHCDGAFVLAQA-------GVLDDVTSTTFPSDIAL-------YRKTFP----------QLSVED-----NVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PPIDILVIPSAEHHLDMDLKDTVMLDFVQKTDRSALFMTSHCDGAFVLAKA-------GVLKGKTSTTFPSDIKA-------YKKMFP----------DLKVAD-----SVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PQIDILVVPSAEHHLDSDLKNKELIKWVQQTGTNATYVTSHCDGAFILAQA-------GLLDDVVSTTFPSDIGK-------MRNQFP----------HLDVRE-----NVWFVHDGKVITSAGGARSFEAAM-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDEVMLDFVRNVDKEAQFITSHCDGAFVLAKA-------GLLDNVVSTTFPSDIDA-------MRDMFP----------ELDIRK-----EVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDKPMIDFVKKVAKDALYVTSHCDGAFVLAKA-------GLLENTVSTTFPSDIDK-------MRAMFP----------NLDIRK-----KVLFVHDKKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PQIDILVVPSAEHSMDKDLKDLIMLDFIKKTDKNALYMTSHCDGAFLLAKS-------GILDSVASTTFPSDVEN-------YRKMFP----------NLDIKD-----NVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDKAMINFVKQVDKEATYVTSHCDGAFVLAKA-------GVLKDKVSTTFPSDIDK-------MRETFP----------DLDIRK-----DVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDIFVVPSAEHHLNSDLEDIAMIDFVKQVDKEATYVTSHCDGAFVLAKA-------ELLKGKVSTTFPSDINT-------MRKMFP----------ELDIRK-----DVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PRIDILVIPSAEHHLDSDLENTEVINWIKQTGSAATYITSHCDGAFMLAQA-------GLLDHVVSTTFPSDVHK-------MRERFP----------NLDIRE-----NVWFVHDGKVITSAGGARSFEAAM-------------- +------------------------------------------------------------------------------------------------PHIDILVVPSAEHHLDSDLENEELIKWVKKTGNKATYVTSHCDGAFILAQA-------GLLNQVVSTTFPSDINK-------MRDRFP----------SLDIRE-----NVWFVHDGKMITSAGGARSFEAAM-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLNDTVMLNFVKRVDKEALFVTSHCDGAFVLAKA-------GLLDKVFSTTFPSDIGR-------YRVMFP----------HLKIKD-----SVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDEALINFVKKVDKEATYVTSHCDGAFVLAKA-------GLLDNSVSTTFPSDIDK-------MRETFP----------NLDIRK-----DVLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVIPSAEHHLDTDLDDEAMISFVQKVDKEALFMTSHCDGAFVLAQA-------GLLDDKVSTTFPSDIDK-------MRAKFP----------ALDIRK-----ETLFVHDGKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDSDLKDTTMLNFVKKVNKDALFITSHCDGAFVLAKA-------GVLNTVTSTTFPSDIDL-------YKKTFP----------NLKVAD-----NVLFVHDKKYITSAGGAKSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDVLVVPSAEHHLDTDLKDTTMINFVKKVDKEARYVTSHCDGAFVLAQA-------GLLDNVASTTFPGDVEK-------YRQRFP----------KLNILD-----KVWFVHDGKYITSAGGARSFEAAL-------------- +------------------------------------------------------------------------------------------------PKIDILVVPSAEHHLDTDLEDEKMIAFVQKVAKDAEFVTSHCDGAFVLAKA-------GLLDDVASTTFPSDIAK-------MREMFP----------QLDIRE-----NTLFVHDGKYITSAGGAKSFEAAL-------------- +--MKKVLCII------YPN------FSLYEITTLTSTLALFDITIDYVASENSIVVSED----G----------------L--SCQPTKTLNQIRIEDYSCVILPGMVN-IGPALQDEKLISFLRSLNEQDILIAAISSSGKFQSKS------------------------------------------------------------------------------------------------ +--KKRIALLV------YPD------FSLQEVANLMYIFRWFDTFTDVIYPELNPVRSEE----G----------------I--LINPVKTCSDFCKDDYDCLILSGCSD-LRQPIRNKKIKEFLGSFVNDNFVIGAICSSPIFLAQA------------------------------------------------------------------------------------------------ +--KQRIALLV------YPE------FSLQEVGNLMALFRWYDSPTDIISTDLSPVRSEE----G----------------V--LVVPDKTTSGFKVEDYDCLILPGISD-IRLSLDNHKLIQFLSELKNHDFLIGAICSGPIFYQWL------------------------------------------------------------------------------------------------ +------------------------------------------------------------------------------------IMATKTFDEVSSRQFDIILIPGGWIEPAKIP--KPLAEFVRAQVLGAKYVLTVCTGSWLLAAL-------GLLDGKRATS------------------------------------------------------------------------------- +------------------------------------------------------------------------------------IVATKTFDEVSSKQFDIILVPAGPLHAESIP--KAVAKFIRDQVPGAKYVLTVCGGSWTLATL-------GLLDGKRATS------------------------------------------------------------------------------- +------------------------------------------------------------------------------------IKPTRTYADEKGEKYDIIRVPAGKFRSM-IM--CQEIEFLKGAAPDAKYVMSVCAGSSILAFA-------GLLDGKRATT------------------------------------------------------------------------------- +------------------------------------------------------------------------------------LLPTHTYATAPK-DLEVLIVPGGLWTR--SPNLNSTIAYIRAVYPSLRYLVSVCTGAGVVARA-------GVLDGRRATTNKAAWAST-------------------IVHRTEWVA-----RARWVVDGNVWTSSGVSAGID----------------- +------------------------------------------------------------------------------------VLPTHTFADAP--DLDVLIVPGGFGWG--EPDLQEHIDYIAQVYPSLEYLITICVGSILAARA-------GVLDGRNATTNKRVWSTT-------------------REYTTNWIG-----RARWVVDGNIWSSSGVSAGID----------------- +------------------------------------------------------------------------------------VLPTHTFDDAPD-NIEVLIIPGGQGTRKPET-TQPIVDFLHARFSKLRFVITICTGTVILSRA-------GLLNGVRATTNKCAFDWVVE---------------ASKEGKVEWVR-----RARWVDTGKIWTASGVTAGMD----------------- +------------------------------------------------------------------------------------VLPTHTFATAP--QLDVLLIPGGIGEVLVDEPLQPAVDYVASIFPSLQYFLTVCSGSGLAARA-------GVLDGKYATTNKQVWDLT-------------------VAKKTKWVG-----KARWVIDGKIWTSSGVQAGMD----------------- +------------------------------------------------------------------------------------ISVTNTFDDEDL-DLDVLIVPGGLGVR--APGLDAIEEYIRKVYPKVKLLITICTGARLAARS-------GVMDGRLATTNKNSWDST-------------------TANDVKWVS-----PARYIRDGDIWSSSGVTSGLD----------------- +------------------------------------------------------------------------------------ILPTHTFADAPD-DIQVLIVPGGPGVRDLQT-SASAEAYIRATHPKLEHLITICTGSILAGRA-------GALDGKLATTNKSAWKSL-------------------TPSGVKWVA-----PARWIRDGNVWSSSGVLSGID----------------- +------------------------------------------------------------------------------------IMPTTTFSENKG-DIDVLIVPGGGGTR---RNMSEEISFVKQTYPSLKYIISICTGATLLSRA-------GVLDNHRATTNKRSWSWATDP-------------STGSLGNITWVP-----TARWVEDGNVFSSSGVSAGTD----------------- +------------------------------------------------------------------------------------ILPTTTFADSKG-DIDVLVVPGGGGTR---RDMSAEIDFVKLTYPKLKYIISICTGATILSRA-------GVIDNKRATTNKRSWAWAT-----------------S--TNVTWVP-----TARWVEHGNVFTSSGVSAGTD----------------- +------------------------------------------------------------------------------------IMPTNTFKQGKP-NIDVLIVPGGGGTR---NDMSEEIAFIAATFPRLKYIISICTGASLLSRA-------GVLQGRRATTNKRSWAWAT-----------------S--HNITWIP-----TARWVQDGNVWSSSGVSAGID----------------- +------------------------------------------------------------------------------------IVPTTTFSQAST-DIDVLVVPGGGGTR---RDMSAEIAFIAATYPRLKYIISICTGASLLSRA-------GVLSGRRATTNKRSWAWAT-----------------S--HNITWVA-----TARWVADGNVFSSSGVSAGTD----------------- +------------------------------------------------------------------------------------VLPTDTLDAVLS-PIQVLLVPGGGTFQ---HDRSVEVAFVKQIYPRLHSIFSVCTGATVLAQS-------GILDGRRATSNKQGWERVI-----------------K--TNVLWDY-----KARWVQDGNIWTSAEPAAGID----------------- +-----------------------------------------------------------------------------------PISATKTFDEVSSKQFDVILIPGGSVTPTT--MSKPLAEFIRAQVPGAKYVLTVCTGSWLVASL-------GLLDGKRATSNKFLF-------------------NEVRKTTVQWVA-----KARWVVDGNIWTSSGVTAGQDM---------------- +---------------------------ALDLAGPMDVFAQDGYRFLLVSAQPGPVRLNSHVLPD------------------------LCCEEA-IGNYDVVLVASSPTY----TYDPTLCAWLREVCGRANIYGSICTGAFALGDA-------GLLDGHTVTTHWESAQ------------------------------------------------------------------------- +---------------------------LLDMAGPLEVFSADHYRIVTLGIDAGQVVANVKVQPD------------------------LLLDQA-GGAYDLLLVPGGPGAY--NECHPALLPWLKAAAPRAGRYGSICTGAFVLGHA-------GLLDGRRVTTHWHYTE------------------------------------------------------------------------- +---------------------------LISLASAVEPLRRELYRWTTLSLDGGQVWADLQITPD------------------------AAMNKA-P-ALDTVIVCGGVGIQ--RAVTREHVSWLQSQARQSRRLGAVCTGSWALACA-------GLLDGFDCSVHWECLA------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RFLPNVTYDDCPRD-LDIILIGGPLPTH---R-PEAADRFMKEAWGKTRVWMTTCIGSLWLAST-------GLLEGKKVTTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KYAPNMTYDDCPRD-LDIVLIGGPWPTH---R-PTAADKFMKEAWEKTPVWLTTCTGSLWLASS-------GVIKGYKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KFVPNMTYDDCPRD-LDIVIVGGTFFSH---R-PAAADRFMKEAWLRTRVWMTTCTGSVWLAST-------GLLDGRKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------MIKPNVTYDDCPRD-LDIVLTGGSLPST---R-TPEATKFIQEAYPKVPVWFTTCIGAMWIAEA-------GVLKGSKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIMPTVTYDDCPRD-LDIVLIGGPSLTH---R-PPQADKFIKEAWTKTRVWWTTCVGSMWLASS-------GVLEGKKCATNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RWLPNVTYDDCPRD-LDIVITGGPYPSH---R-PAAANRFMKEAFPKTRIWMTTCTGSMWLASS-------GALDGKKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------MYLPNVTYDTCPRD-LDIIIIGGPLPSH---R-PPPADRFMKEAWLQTRVWMTTCIGSMWLAST-------GLLDGKKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KVQPTHTYDDAPRE-LDILLIGGPMLTH---R-PEAADRFMKETYPKTKIVMTTCVGAMWLASS-------GVMNGTKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KFVPNITYDDCPRD-LDLVLIGGPLPSH---R-PPQADRFMKEAFVKTRVWMTTCIGSPWLASA-------GVLKGKKATVNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KIVPTHTYDTAPRD-LDMIVVGGPLPSH---R-PEASLKFFREAVEKTKIIFSVCTGSMWLASS-------GILDGNKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIIPTHTYETAPRD-LDILLIAGPSPSH---R-PAGSTEFLREAFDKTKVIFTVCTGSLWLASS-------GVLNGRKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TCVPNTTYAEAPVD-VDMVFVGGSLTHN------EDSLQYMRAVYADPKVIMTVCTGGAWVADS-------GILDGLNATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KILPTHTYASCPVDDVDIMLIGGPLPHV---R-PAESLKLIRRFCERSATLMTTCVGSLWAAAS-------GVLEGRRATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RISPTHTYETAPVD-LDILLVGGPPYSV---R-PPASLEYLRKLKAAGGTIVSTCVGGMWLADA-------GILDGRKATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KYLPNVTYDDCPRD-LDLVLIGGNGFES---Q-SEASKKFIREAWPKTRVWMTTCVGTLWLASA-------VDLTGLKVTTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RYMPNVTYDDCPRD-LDLVLVGGNTPNV---R-PEAATVFMREAWPRTRVWMTTCTGALWLADA-------VDLTGKRVTTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RYAPNVTYDDCPRD-LDLVLVGGNTPGV---R-PEAASRFMREAWRRTPVWMTTCTGALWLADA-------VGLDGRRATTNR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------GVCLTHTIDDKDPGNLDILVIPGPEPTTI--P--DKTQEFVRAHN--KTTFLVICSGAFVTARS-------GIYGGRHVTGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SLQLTNSLTDSAPGKLDILLIPGPPPKSM--P-PAEYLDFVRAHF--DTPILSICTGAFVIGYA-------GIVAGREVTAPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SLQLTHSPTDPAPGALDIILIPGPEPSTV--P--DDYLDFVRAHN--GTHILSICTGILVVAHA-------GIAKGKHATGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------FLRISKTTTDSEPGMLDVMMVPGPDPRIV--S--DDTQSFLKSHA-GRVDILSVCTGIFLVAQS-------GILEGLSASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KVAVTDSIETSPA--LDVLMIPGPPPNFV--A-SEAVGAFIRAQVEHATAVLSVCTGIIPLAQS-------GVLKGKTATGPP----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------VIKTPKTITDKDPGMLDVLLVPGPAPDAQ--F--GEVLGFVRRHA--GCDVLSVCTGCRVLAAA-------GVLEGKRASAPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------FIRVSKTIDDPGAGSFHIILVPGPDPATI--F--DKVRAFLKSHA-GTTDIVSVCSGCILLGQA-------GVLKGKRACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIQPTSSLTSPAPGTLDLVLIPGPSPKTM--P-PAEYLDFVRAHF--GVLVLAVCTAAFVVGYA-------GVADGRRVTAPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIRVNSSMKDSVPGNLDILFLPGPSPRVM--P-PAEYLDFIRRHD--GTTIMTICTGSLVAAHA-------GITKGKISTSPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SINLTDTVSSPSPGNLDILMIPGPDPNQV--P--SDLKTFVRQHH--GTTILSICTGCIVAAHA-------GILNGKRATGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TLPVTDGLDSPAPGNLDTLLIPGPDPNLV--P--DAVLDFIRAHR--ATDFLVICTGSFPAGYA-------GLLDGKRVTGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KTPITHHLSDPEPGKLDIVLVPGPAPDG---K-WSDVLEWLRAQM--TTDCLSVCTGIYLFGEA-------GLLKGKKACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIAITHSLATAPP--LDILFIPGPPPVFV--N-RPAVDAYIQSAVARGTTILSICTGAFPVAAA-------GVLDGRTATAPL----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KLSITHSLSNAPP--LDILIIPGSAPIIT--A-RPAIDAFIQSAAAHGTTILCICTGIFPTAAS-------GVLEGRAATAPL----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KMLATHDISHPDPGKLDIVLVPGPDPSTT--D-WDNVLGFLKDHA--TTDVLSVCTGVFLCGAA-------GVMEGRMVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TMVPTHDILHPDPGKLDVVVIPGPAPD-L--V-LADDREFLRRHA--ATDILSICTGIYVCGQA-------GILAGKKACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TVRATHDITHPDPGKLDIVLVPGPDPE-A--K-WDPVLDFLLGHS--NTDVLSVCTGIYLCGSA-------GLLDGRTVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIAPTHDISHPDPGELDVLLIPGPDPS-G--S-WDDVLGFVRGHA--TTDVLSVCTGIFVCGAA-------GLLHGKTVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------VLKASHTHRDADPGKLDIVVVPGPDPSS---T-YEEGLEWLRKQA--GVDILSVCTGILVCASA-------GILDGKLASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------VIKATHDYTEAEPGKLDIVVVPGPDLPV---E-LDGGLRWLREQS--GVDVLCICTGIFVCGAA-------GIVDGKQASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TIKATHSYEDPAPGQLDIVIVPGPDPTQT--A-FDGGLEWLKAQF--GVDILSVCTGIYVCGAA-------GILEGRRASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KLHATHHIADPDPGKLDILLIPGPDPR-V--S-FEPVLEFVRGHF--STDILSVCTGIMLCGAA-------GILDGRTACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RILATHHYADAEPGTLDVVLVPGPDPFV---E-PEEPLEWLRKQG--GTDILSVCSGVFLLGGA-------GLLKGRRACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KVLATNHFSDDEPGKLDIIIVPGPDPST---K-FDPSLEWLRQQG--NTDILSVCTGIFVCGYA-------GLLKGRTVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TLKATHDYTDPEPGNLDIVVIPGPELTV---K-FEGTLDWLRRQF--GVDILSICSAMFMCGEA-------GIADGKTVAGTR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------VLKATHVYTDEEPGKLDMVVVPGPDPTE---K-FAEGLKWLRGHA--GVDVLSICTGLFICASA-------GIADGKRASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SVHASRTYEDDDPGKLDIIVVPGTDPAD---E-FEASTKWLRDHF--GVDVLCVCTGVYLCGAA-------GILDGRRVSGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------AVVATNHYSDAEPGRLDIVYVPGPDPNA---H-FPGAVDWLARQG--GVDILSVCTGIVVCGAA-------GLLRGKEICGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------QVVCTHHLSDPAPGQLDIVLVPGADPST---K-WDAVTDWLAAHA--ETDILCVCTGIYLCGAA-------GLLKGRKACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIACTHHLSDPAPGRLDIVLVPGPDPTT---D-FSEATDWLAAHG--ETDILCVCTGIYLCGAA-------GLLNGKRASGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SILCTHHYSDPQPGKLDIVLVPGPDPKI---N-LQAALSWLAGHA--KTDILSVCSGIYLCGAA-------GILKGKKACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KLLCSHHVSDPAPGTLDVVFVPGVDPTA---S-FSETTDWLAAHG--RTDILSVCTGIYLCGQA-------GLLKGRKVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KLHCDHHFSEPSPGELDILLVPGNDPDRQ--A--DNLSAWLAAHG--TTDILSVCTGLYLCGWA-------RLLKGRKVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RIELSNHFSDAEPGKLDVVLVPGPDPRD---T-WDDALSWLRQQG--GTDILSVCTGIYLCAAA-------GLADGRRVCGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RLLVDRHLSSPDPGTLDVVLVPGPDPAA---A-HDVALEWLAAHHETGTDVLCVCTGIFLCGEA-------GILKGRRACGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------PQHPTHTYADC-P-EIDYLIVPGPDPALP--L-PEGCPAFLQSLMDTFKALLTVCTGSLPVAQS-------GILDGLHVCSNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------PQLPTHTYDDC-P-DLDYIIVPGPDPTVP--L-PKGCATFLQKRFTKLKAILTVCTGSMAIAQA-------GILDGYHVCSNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KQLPTHTYASC-P-PVDCVLVPGIDPLSS--L-SEGCTEFVKKKWPKV-VFLTVCTGSLVLAQT-------GVLDGYHVASNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------AQIPTHTFKNPPP-HLDYIVVPGASTKVP--L-SPDCAHFLKTYFPKIRALLTVCTGSICIAPT-------GLLDGHCVCSNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KQTPTHTFATC-P-RVDYVFMPGNSLKPV--V-PPEFTKFVQTRFPKV-RFLTICTGSIVLAPT-------GILNHLRVASNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------ETAVTHTFADA-P-ALDVILVPGGTGVIN--A-TLEIEEFLVRRADQAEYILGLSFGVTHLARS-------GLLNSKRATTNK----------------------------------------------------------------------------- +------------------------------------------------------------------------------------TSMQDVIDRD-L-QLNVVLIPGAAPMYI--E-NVDYFQFIKESLQRSEHILSICSGARIVAAT-------GILDGKAATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SLTATHTFATA-P-PLDILLIPGGMGNMV--L-VESIESFINSRYKSLSYLLSVCTGSVSLARS-------GVLKNKKATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------QIVATHTFETA-P-PLDVLIVPGGIGDLT--L-TEAIEEFIAARFDSTKYVLSVCTGAGFLARA-------GVLDGRRATATK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SMLATHTFSNA-P-DLDIIIVPGGTGVLN--A-TLIIEDFLNARFDCAEYLLGVSFGVTHLARS-------GLLNGKKATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIEATHSFDNA-P-PIDILYVPGGLGVVT--L-DQSIEDFINLRYPRAEYLVGVSFGVAPLARS-------GVLNGKRATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SLVATHSFSDA-P-PLDIILVPGGTGNRV--L-EEAIEDFVRERYPSLKYLLTVCTGAASVAKS-------GLLDGRRATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIEATNTYLDA-P-AIDVLFVPGGLGTIP--L-DQWIEDFINSRIDQLDYIASVCTGAQFLAKS-------GVLKGKRATTSK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------TITATHTFKNA-P-ALDILFVPGGEGNVV--L-AQWIEDFVASRYDRLDYLLSVCTGSASLAKS-------GVLNGKRATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------QVVATHTFETA-P-KLDILLVPGGTGNVA--L-EQKVEDFVRERYPELEYLLSVCTGAITLARS-------GVLEGRRATSNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KILPTHTFTSPPTHPIHILIIPGGIGTRS--T-LKPVVDYLSHFFKCLKGVFTVCTGSIVLARK-------GILEGIKATTNK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------YLQPDSTFDDYLTREIDVLLIPGGVGSRL--T-RVSLYDFLPKIA--GTAIITVCTGSDILAKS-------GLLDGRRATTNM----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------QVVVDATFAEVETAKYDVLFIPGGIGSRV--R-RRPLINFTQAIA--GLGIMTVCTGSDILGYT-------GLLDRRRATTNM----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------RFAVDLTFADALSQSWDLIFIPGGIGSRV--F-YEPLLDFIRRVT--SLGFMTVCTGSDILART-------GLLDGRRATTNM----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------KVVPDVTFQDYLLKPIDVLLIPGGPGTRL--D-RIEAQDFIKAVA--RHSVITICTGSHVLAQT-------GLLNNLDATTNS----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------QMLPQCTFADMIFKPIDVLIIPGGPGTRL--N-RIELQDFLTAVA--RHSIITICTGSHVLSQT-------GLLDGRQVTTNS----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------YLTPDTTFDEYLLKPVDVLFIPGGFGSRV--Q-RVALVDFIPKIA--QEAIITVCTGSDILART-------GLLDGRRATVNM----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIALTHPLSSPLPGSLDILFVPGPNPKTV--P--SAHNAFLRGHA--RTHILVVCTGIFAVGHS-------GILDGRECTGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------GIRLNASIHDTSTDSLDILVIPGPDPKYV--P--DSVLAFVKAHH--GNDILSICTGSYVAGYA-------GILDHKNVTGPR----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------GIRLTASVHDASAGNLDILVIPGPDLKYI--P--DSVSAYVRAHN--GNVILAICTGCYIAGYA-------GILDQKNVTGPK----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------------------------------------------MYAEKGELYGAICAAPAVTLAH------WGMLKGLKATCYPSFMEKFTS----------------------EV----IPVNSRVVVDRNVVTSQGPRTTVEFALALVEQ--------- +---NSVAVILSGCG-VFD------GSEVTETISILIQLQKMNVKVHMFAPNQDQH---HVINH--TNGEVMN--EKRNVLEQSKLFEVRDIKTLNAEEFQALLIPGGFGVASNFAENEDVSKAIQDFNNQAKPIGAVCISPILIAKVLG-EKKPMITLGKRQTEKDN---------------------------------------------------------------------------- +---KKVAIILSGCG-VYD------GSEVTEVVSLMVHLNKSHVSFQCFAPNQDQL---HVVNH--ITGETTT--ETRNVLVEARIAEVKDITQLKGEDYQAVLLPGGFGAASDYAVNSEVERVLRVILHINSLYISYNISSFIISKDLN-QIKLHLLKNRNTKNLKS---------------------------------------------------------------------------- +---KKVAIILSGCG-VYD------GSEVTEVVSLMVHLNKSHVSFQCFAPNQDQL---HVVNH--ITGETTT--ETRNVLVEARIAEVKDITQLKGEDYQAVLLPGGFGAASDYAVNSEVERVLREFHSQKKPIGAMCISPLILAKVLQ---KPKITMGRVQDTPNK---------------------------------------------------------------------------- +------------------------------VSSLLQSGQERAWRLRVFSLEEQSVTAELHVMAD------------------------ATMQDTSPLDLQLLIIPGGHYPP-QTWSDIRLHRFLRQYDGQRRWIAASTEGVVCIAAA-------GLLGGTSYSAPIHVAH----------TY-----AHVLR--HAIHQ------QSPVTVDGNVISSDG----------------------- +------------------------------VALVLEGLRRLNRRARVITLDGRPCQAELVIQAD------------------------GGVEEPVPPDAGLCVIPGGLYEA-DSWGDLRLHRYLRRFSTTGGYFAASGQGLLCLASA-------GILGGLRFTAPVSVVQ----------AH-----EPLFR--HAIFE------PGPVVMDGNVISSDG----------------------- +------------------------------VATLQRLLTERGWSMRTLTIGGQTVCDGVRLVPD------------------------GDVYNTFPGDFGLLVVAGGTITE-QDTRDPSLMRFLRQYDVSGGAIACIGSGAAIVGAA-------GLLGGLHTAVDSDVVQ----------AF-----PDAFN--HAILT------DELVALDGSVTTAHR----------------------- +---------------------------ALDAVGPYEVLLLPNVEVLFVSHQPGLY-----AA-----G-----------MGMLTLQATASFDQVT--RPQILVVPGGMG-TRRLLQDRVILDWIRKVHEHTLYTASVCTGSLLLGAA-------GLLKGIEATTHWNSHEL------------------------------------------------------------------------ +-------------------------------------------------------------------------------------------------------MPGGFGVAKNLSVDENILALVKDFHRTGKPIGAICIAPALMALS---------LGDPTLTIGSDE-----------------ATAAEIEKLGALHKN--CPAN-ECVVDKKIVTTP------------------------ +-------------------------------------------------------------------------------------------------------LPGGFGVAKNLRVHGTVASILKAFHQSKKPIGAICISPAILALT---------FGDPTITLGSDL-----------------NIAKEIEKTGSIHHV--CQTK-ECIVDNLFATTP------------------------ +-------------------------------------------------------------------------------------------------------MPGGSGVLNNLAVQEDVVRVISEFKSANKPIGCTSYANVLISLV---------IPEIEITLGGDDEEDY----------PNTPLIDNLTARGTTITS--TEFG-DICVDNKIASIA------------------------ +-----------------------------------------------------------------------------------------------------------WGGQEPIQSDHGCGAGLKDFHQAGKPIGLCCIAPVLVARV---------LPGVTVGQEEEEGGKW----------PYPGTAEAIRCMGGKHFP--GDVH-QAHVDNKIVTTP------------------------ +-------------------------------------------------------------------------------------------------------MPGGFGAAKNLTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKI---------FDFLRLTIGTDI-----------------DTAEVLEEMGAEHVP--CPVD-DIVVDNKIVTTP------------------------ +------------------------------------------------------------------------------------------------------------------NVIPEVVKVIQEFHNAKKPQGFLCISPILAARV---------LCTVKITLGKNSCDKW----------PHRGAIEDAKKMGATVEL--RNWD-EVSFDNLIFSSP------------------------ +----------------------ANGSEEMEATIIIDVLRRAGVHVTVASCEDDLV-CEMSRKVC-IR-ADC-------------LIQEVVVDDNSRSSFDAIVVPGGMPGAERLAENASLDALLKRQKEEKKLIAAMCAAPAVVLLG------KNLLEASEATAHPAFD-----------------LGEAFAKKRVCYSKAS---N-----GQVVITSQGPGTAIEFALALVKE--------- +-----------------------DRLNAEDLMRATRPLERAGYGVAVVSGGEAM------LTAKSERSDDV--------Q----LLAASTIGDMDFDRYCALILPGGVGEIS-----ESARLVADRFLEAGKPIIAMSDGVKLLADAA----------------------------------------------------------------------------------------------- +-----------------------DGFDAGDLTDIAGSAERAGYRTIMISPKKGL------ITGRPQGGDEM--------N----FVVDAQPGEKAASAFTGLVLPAGAASIERLRNDQDARLLIADFLRAGAPMCALGEAVALVAEIA----------------------------------------------------------------------------------------------- +-----------------------PGFSVPDLNAAASAAERGGYKLKVASGARAL------VSGRTETGEEM--------N----FVVDAGLDEVTADEGAGLVLPGGRRAVDALNDSNDALRLVQDMFASGRPIFAAGEALTMLAEVS----------------------------------------------------------------------------------------------- +--------------------------------------------------------------------------------------PTHTFSSA--PPLDVLLIPGGYGTRGSLPGLEDAIVFIRARFPELKYMITVCTGARLAARA-------GVLEGRRATT--NKRAWLD-----------------TKEMGVKWVA-----HARWVVDGKCWTSAGVSAGID----------------- +--------------------------------------------------------------------------------------PTHTFSEP--PPLEVLFVPGGLGTRAPADQLEPVVSFIRTAYPSLKYLITVCTGAGLAARA-------GVLDGKRATT--NKKAWVE-----------------TVALKTYWVA-----KARWVADGNIYTTSGITAGID----------------- +--------------------------------------------------------------------------------------PTHTFDNP--PKIDVLIVPGGFGAGPKPAGVERVVQFLKDQYPSLKHLLTVCNGAGLAARA-------GILDGHRATT--NKQLWQA-----------------ITTTKTHWVA-----NARWVVDGKLWTSSGVSSGTD----------------- +--------------------------------------------------------------------------------------PTHTHSPP--QP--------------PAADIQPHIDFLAATYPKLQYLVTVCTGAGLAARA-------GVLDGRRATT--SKREWNA-----------------TTSLQVNWVS-----HARWLRDGNVFSGSGVTAAID----------------- +----------------------------------------------------------------------------------------------------------------------------------------MCVGSLAVART-------GILKGKKATTYSASKRH--------------DNLKILQDCGAIPVK------ERIVVTGRIITNRGPDTALDVAFKLLE---------- +------------------------GAVVSDALAPFEVLAAGAFNVYTVAPEARP----VTLTGGL-D-----L--IPD----------LSFADLDSSAPDVVVVPALPD--LGEPTTRPVTDWLNRQASRGSLLMSVCNGSGVLASA-------GLLDGRKATAHWIRIGGFE------------------DEFAVDWIR-----GTRYVDDGNILTTAGILSG------------------- +------------------------GAVVSDTLAPYEILAAGGFNVYTVASGEHP----VPLTGGL-D-----L--VPD----------LTFAGLDGGSADLVVVPAMPD--VGRPTTKPVIDWLEAQADGGALILSVCNGSAVVASA-------GLLDGHRATAHWLRLDEWD------------------DTYAVDWVR-----GTRYVDDGDVISTAGILSG------------------- +------------------------GAVVSDALAPYEILAAGRFNVYTVAPHREP----KPLTGGL-D-----L--VPD----------LDFAGLAGSRPDLVVVPAFPD--VGEPSTEPVTTWLRDQAARGSKLLSVCNGGAVLASA-------GLLDGRPATAHWLKVDDWA------------------AEYAVRWVR-----GERFVDDGAVVTTAGILSG------------------- +------------------------GAVVSDTLAPYEILATGAFNVYTVASDADP----VPLTGGL-D-----L--VPD----------LTFAELDGGPADLVVVPAMPD--VGRPTTKPVTDWLERQANGGTLILSICNGAAVVASA-------GLLDGHRATAHWLRLDEWA------------------DTYAVEWDR-----GTRYVDDGDIVSTAGILSG------------------- +------------------------GAVVSDTLAPYEILAAGAFNVYTVAPEARP----VTLTGGL-D-----L--IPD----------LAFADLDSSAPDVVVVPALPD--LGEPTTRPVTDWLKRQSAKGSLLMSVCNGSGVLASA-------GLLDGRKATAHWIRIGGFD------------------DEFAVDWVR-----GTRYVDDGNIVTTAGILSG------------------- +------------------------GAVVSDTLAPYEILATGEFNVYTVASDSHP----VPLTGGL-D-----L--VPD----------LTFAGLEGGSADVVVVPAMPD--VGQPTTKPVTDWLATQANGGALLLSVCNGAGVLASA-------GLLDGRQATAHWLRIDEFE------------------RRYPVDWVR-----GTRYVDDGDVISTAGILSG------------------- +------------------------GAVVSDALAPYEVLAAGAFNVYTVAPEVRP----VTLTGGL-D-----L--IPD----------LGFADLDSSAPDVVVVPALPD--LGEPTTRPVTDWLKRQSARGSLLMSVCNGSGVLATA-------GLLDGRKATAHWIRIDGFD------------------DEFAVDWIR-----GTRYVDDGNILTTAGILSG------------------- +------------------------GAVVSDALAPYEVLAAGAFNVYTVAPQARP----VPLTGGL-D-----L--SPD----------LGFADLDSSKPDVVVIPALPD--LGEPTTRPVTEWLKRQSSRGSLIMSVCNGSGVLASA-------GLLDGRQATAHWIRIGGFD------------------DEFAVNWIR-----GTRYVDDGNIVTTAGILSG------------------- +------------------------VSEITDVLAPYALLAKGLYNVYTVAETSSV----RSLSGGL-D-----L--LPD----------YSFAGLAKQPPALVIVPAITE--IQASQNQPVLAWLRQQSQAASTVMSWCTGAEVLAES-------GLLDGLPATAHWADLSSLQ------------------KRYKVKWQN-----NQRYVDINQIITTAGLTSG------------------- +------------------------GANVADTLAPYEVFARGGFNTYLVAPSARP----VTLGGGL-T-----V--VPQ----------HSFASLAPDGPAIIVVPQLHG------HRGPVTAWLTAQYRTHATFMSVCVGAEYLAET-------HILDGKSATSHWLKLIGLR------------------RGYGITWVA-----GKRFVEDGRVISTAGVLSG------------------- +------------------------GTNVADSLAPYEVFARGAVNVFLVADEPEP----ITLGGGL-T-----V--LPQ----------HTFAEIDGGGPDVVVVPQLHG------NIDDEMRWVTEIFEPKSLVMSVCVGAEYLAAA-------GMLDGRRATTHWLKLIGVR------------------RDHQVDWVD-----GVRFVEDGRIMTTAGVLSG------------------- +------------------------GGNVADSLAPYEVFARGTFNVLLVAPTDQP----VPLTGGL-D-----V--VPD----------RTFDALDGRPADVIVVPQIHG------STDRVVSWLSEQDEGAPLIMSVCVGAGTLADA-------GLLDGRTATSNWLGLIGLR------------------RSYDVNWVA-----GQRFVDTGDVITTGAVLSG------------------- +------------------------GTVATDAMGPYGVFAADRFDVRTVAASRAP----VALSGGL-T-----T--VPD----------ATFDDYALPRPDLVVVPAIAD--PSGAGEAELRTFIETAHDAGARVMGVCAGARVLVET-------PVLHGKRATSFWSDIDGMT------------------SAHETTWVR-----GQRWVEDGDVLTTAGVSSG------------------- +------------------------GSVAADVLAPYSVFAGPRFGVRVVAQELSP----VTLSGGL-H-----V--VPD----------NTFAQ--VDAPDVVVVPAVVD--WAGPGEAALREWVARQADRGALVLGVCSGAKVLAEA-------GVLDGRSATTFWSAVDGMR------------------DDHAVEWVA-----GKRYVEDGDVITTAGVSSG------------------- +------------------------GTIGSDALAPYEVFASPKFAVYTVAATHTA----QPTQGGP-Y-----I--VPT----------YTFADTTTPRPDVVVVPAVAT--ADGPAEAPLRAWVTDQAGAGARILSVCNGAEILAAA-------GLLEGRTATAHWSRLHTYA------------------KKYAVNWVA-----GKRFVQDGPITSTAGVTSG------------------- +------------------------STVASDILAPYDIFASPAFTTYIVANVATP----AALEGGP-S-----V--LPT----------YTFADVDTLKPDLVVVPGLGD--PTGAKEAPLREWVSHQHDSGAKVLGVCSGSLVLSAT-------GMLDGLEATSHWSRISALE------------------KSRAVHWLR-----GRRWVQDGSITTTAAVSSG------------------- +------------------------VTEVFDFLVPYEMFAMEAYNVYGVAPDRGI----KSLTGGL-D-----V--VPH----------YSFEEMDNGSPDIIVIPFMPM--LDENKYAPVREWIKKHASQ-TILLSICNGAENLADT-------GLLSGKSATTHWGDIGRLI------------------KTYDIDWKK-----DQRYVPVDHIVSSAGLTSG------------------- +------------------------PTEDFDFLIPYTLLSMDAYNVYAVAPDKNV----KSLSGGI-D-----V--LPH----------YTYKELDNKSPDIIVVPYMPI--VDEQKYQPTREWIRQHSGKTTTFLSICGGSQNLADA-------GLLKGKSATSHWQVLPILM------------------KQYDTHWKE-----DVRYVHDGNTLTSAGQSAG------------------- +------------------------VTEVFDFLVPYEMFSMGSYNVVAAAPDKNI----KSLTGGL-D-----V--APH----------YTFDELDGKGPDIIVIPFMPN--LDEAKYKPVRDWIRKHSSE-TTLLSICNGAENLADT-------GLLNGKSAATHWGDISRLE------------------KKYEITWKR-----DQRYVSDGNIVSSAGLTSG------------------- +------------------------VTEIFDFLVPYEMFSMESYNVFAAAPDKNI----KSLTGGL-D-----V--VPH----------YTFDELDGKGPDIIVIPFMPI--LDEAKYKPVREWIRKHSSE-TTLLSICNGAENLADT-------GLLNGKSAATHWGDIDRLE------------------KQYEVRWIR-----DQRYVPDGNLVSSAGLTSG------------------- +------------------------TTEVFDFMVPYEMFAMGAFNVFAVAPDNKV----KSITGGL-D-----L--IPH----------YSFKEMDGKSPDIIVIPYMPM--VDKKKYQPVREWIQQHKD--ATLLSICGGSANLADT-------GLLKGKSATIHWQYFDKTK------------------NKYDTHWKR-----DQRYVHDGNIVASAGLTSG------------------- +------------------------PTEDFDFLIPYTLFSMDAYNVYAVAPEKNI----KSLSGGL-D-----V--IPH----------YSYKELDNKSPDIIVVPYMKM--TDEKKYKPTREWIQKHSNKTTTFLSICGGSENLADA-------GLLKGKSATSHWQALPLLI------------------KKYETQWKE-----DVRFVHDGNTLTTAGQSAG------------------- +------------------------TTEDFDFLIPYTLLSMEAYNVYAVAPDKDL----KALSGGL-D-----V--VPH----------YTYAELDGKDPDVIVVPFMPI--IDEATYAPTREWIQKHAND-TTFLSICGGSGNLADA-------GLLKGKSAASHWQAIPSLR------------------VFYDTTWVE-----DVRYVHEGNTLTSSGQTAG------------------- +------------------------TTEIFDFLMPYELFSMEKYNVVSVASDTKL----RTLSGGV-D-----L--FPN----------YSFAQLDGKSPDIIVIPYMPS--VNQAGYQPVREWIQKHGE--TTLLSICGGSGNLADT-------GLLKGKSATSHWQAIDLEQ------------------KKYDTEWLK-----DHRYVAQGNIVTSGGQTGG------------------- +------------------------TTEGSDFMIPYELFSREAFNVFAVASDNQV----KSLTGGL-D-----L--VPH----------YSFTELVGKSPDIITIPFMVT--NDAEKFAPIRKWIQQHAN--TTFVSICGGSGNLAAT-------GLLKGKSAATHWQNLVVFP------------------KQFETNWLA-----DQRYFH-NNVISSAGVSSG------------------- +------------------------ATEGLDFMIPYEIFARGAYNVYAVAADTGI----KTLSGGL-D-----V--VPH----------YSFQEMDGKSPDIIAIPFLT---DQEETFEPAKEWILKHQE--TTLVSICGGAGNLAST-------GLLNGKSSTSHWQTIWSRK------------------INYQVDWKR-----DLRYVLADNIVSSAGITSG------------------- +------------------------VTEVMDFMESYELFARQAFNVYAVAPDHGV----KTLSGGL-H-----I--LPH----------YTYEELDGGSPAMIVVPAIPF--MDETKYRPTRQWLQRHAGE-TTLISICTGAENLADA-------GLLKGRSAATFWADIDRLE------------------REYDTHWIR-----NQRYVVSGNIVTSAGITSG------------------- +------------------------STEVFDFLVPYEMFAMEAYNVYGVAPDREI----KSLTGGL-D-----V--VPH----------YSFDEMDGKSPDIIVIPFMPI--LDEKKYTPVREWIQKHASK-TLLLSICNGAENLADT-------GLLNGKSAATHWGDIDRLI------------------KQYKVQWVK-----DLRYVPQGNIISSAGLTSG------------------- +------------------------TTEVFDFMVPYEMFAMRAYNVYAVAPDKNV----KTLSGGL-D-----L--MPH----------YSFDELDGKSPDLIVIPAMPR--VDEAKYKPVREWIQKHAD--TKLLSICAGGVNLADT-------GLLKGKEATTDWKSFDYHI------------------NKYETKWRR-----DLRYVADGNIVSSAALTSG------------------- +------------------------VTEVFDFLVPYEMFAMEAYNVYGVAPDRKI----KSLTGGL-D-----V--VPH----------YSFDEMDGKSPDIIVIPFMPI--LDEKKYAPIREWIRKHSGK-TTLISICNGAENLADT-------GLLNGKSAATHWGDIDRLI------------------KNYEIQWVK-----DRRYVPQGNLVSSAGLTSG------------------- +------------------------TTEVFDFVVPYQMLAMEAYNVYAVAPTKNM----TSLTGGL-D-----L--VPH----------YSFEEMDGASPDLIVIPYMPL--GDQEKYKPVREWIQKHSE--TFLLSICGGAINLADT-------GLLQGKSSTIHWQFFDQTR------------------RSFETNWIR-----DQRFVVGGNMVSSAGLTSG------------------- +------------------------------------------------------------------------------------------------PPLDVLLIPGGYGVRAD--DTESLIDFIRRTYPSLKYVITVCTGSWLAARA-------GILDGKRATSNKASWAG-----------------T--KVAGVKWVS-----HARWVVDGNIWTSSGVSA-------------------- +-----------------------------------------------------------------------------------------------APPLDVLILTSSYD-MDPLINNRSLIEYVASTAKQAEWMASNCSGAYLLAEA-------GVLDGKQATTWAGGERDFQS---DYP--------------QVNVLS-----DKNYVIDDKVLTSNGSLVS------------------- +-----------------------------------------------------------------------------------------------PLTLDVVIVASAYN-MSPVLNNETLIKFVEDQHGQASWMASNCSGAMILAEA-------GVLDGKNATTWAGGEEDFAD---DYP--------------KVKVQF-----DKNFVIDDGVLTSNGGPVS------------------- +-----------------------------------------------------------------------------------------------SPKLDALILTSSYD-MDPLVNNKALIRYISSTAKTAEWMASNCSGAYLLAEA-------GVLNGKQATTWAGGERDFQR---DYP--------------KVEVLT-----DKNYVVDGNVLTSNGSLVS------------------- +-----------------------------------------------------------------------------------------------SPEVDALIVTSSYD-MDPLIENKVLIDYIASTSKKAEWMASNCSGAYLLAEA-------GLLNGKQATTWAGGERDFQR---DYP--------------KVKVLS-----DTNYVVDGNVLTSNGSLVS------------------- +-----------------------------------------------------------------------------------------------LPELDVLILTSSYD-MDPLIENNQLIEFIQATSKEADWMASNCSGAYLLAEA-------GLLNGKKATTWAGGESDLQK---DYP--------------AVKVQV-----NQNFVVDDKVITSNGSLVS------------------- +-----------------------------------------------------------------------------------------------TPELDAIITTSAYD-MDAPNASQALMTLIQKTAAKGGYLASNCSGAFLLAQA-------GVLDGKKATTWAGGEKDLQK---QFP--------------KVNVQV-----DTNVVVDGNIVTSNGSLVS------------------- +-----------------------------------------------------------------------------------------------LPELDVLVLTSSYD-MDALIENKDLIHFIKTTSKAADWMASNCSGAYLLAEA-------GLLNGKKATTWAGGENGFQR---DYP--------------AVKVQV-----DQNFVIDDGVITSNGSLVS------------------- +-----------------------------------------------------------------------------------------------SPKLDALIVTSSYV-MDSLFKNADLTTFLTEQAKTASWLASNCSGAFLYAHA-------GLLDGYTATTWAGGEPQLQR---EFP--------------RINVIE-----DRNVVVDRNRISSNGGVPS------------------- +-----------------------------------------------------------------------------------------------ELDLDILIVNSSYD-MDWLFENDDLTKFMRDQAEKVEWLASNCSGAFLYANA-------GLLDGYRATTWAGGEAELQR---KFP--------------KIDVVV-----DQNVVVDRNRISSNGGVPS------------------- +-----------------------------------------------------------------------------------------------NPNLDALIVTSSYV-MDSLFENKDLTAFLKKQAENVSWLASNCSGAFLYAHA-------GLLDGYTATTWAGGEKQLQR---EFP--------------KINVIE-----DRNVVVDRNRISSNGGVPS------------------- +-----------------------------------------------------------------------------------------------APELDVLLVGSAYD-MDPVLDDTAFMDFIRARGEVADWLASNCSGAYVLAAA-------GFLNGVRATTYPGGEIWLKL---NHP--------------RVRIDM-----NETVVVDKNVITSNGSMVS------------------- +-----------------------------------------------------------------------------------------------CPELNVLVVSSSYD-MEAVVASAEIVEFVKSKGNATDFTMSNCAGAHLIGAS-------GVADGRKIVTYIGGGELLQE---TYP--------------ELVVQD-----DSSFVRDGKMISSNGNLAS------------------- +-----------------------------------------------------------------------------------------------CPKLTALFVPSAYD-MYAQVHNEKIVNFIKEKNKETEYVVSNCAGAQLIGKS-------GIADGFKIVTWIGGGEQLQK---DYP--------------NLKVQD-----ENTFVEDGKFSSSNGNLAS------------------- +-----------------------------------------------------------------------------------------------PPDLDVLVVPSSND-PDQQVKDSVLINFIREQNKTTDYIASHCAGAFMLGES-------GIADEKEVVTYCSGSEALQE---AYP--------------SLIVMD-----DRSVVQDGKFISSNGNLVS------------------- +-----------------------------------------------------------------------------------------------EDEYDALVFACGDAV-PVFPYNVTMLEIIKTFGEKGKIMIGHCAAAMMFDFT-------GITKGKKVAVHPLAKPA-------------------IR--NGEAT------DNSSEIDGNFYTAQDENNIQTM---------------- +-----------------------------------------------------------------------------------------------EDEYDALVFACGDAI-PVFPHNIMLMEVLKTFGEKGKIMIGHCAAALMFEKA-------GITKGRKLAVHLLAKPA-------------------IV--NGTAT------DNATETDGNFYTAQNENKIAAL---------------- +-----------------------------------------------------------------------------------------------EHEYDALVFACGDAM-PKFPYNVDMLSVIKNFAAQGKTIAGHCAAALLFDNL-------GIAQGRRVALHPFLKPV-------------------VK--SCIGT------DEKAVIDGIFYTAQNENTISCL---------------- +-----------------------------------------------------------------------------------------------ENEYDALVFACGDAI-PEFQFNQDMLAVMKNFSEQDKILIGHCAAALLFDNL-------GIVNGKKVALHPFVKSV-------------------VK--GCIGT------DEKSVIDGNIYTAQTEDAIPSL---------------- +-----------------------------------------------------------------------------------------------SGDYEALVFSCGDAM-PTFNYNQDMLAVIKEFGEAGKLIAGHCVGGLLFDIA-------GITKGRTVAAHPFVQSA-------------------IK--GGKAT------NEPYAIDGKLYTAQTENTLSSL---------------- +-----------------------------------------------------------------------------------------------SDEFDALVFSCGDAI-PVFPYNVDLLKVIQEFATKKKIMAGHCAAGLIFEIA-------GITEGKRLAIHPLAKAA-------------------IQ--KGIAT------DEPAVIDDNFYTAQCEHTLPVL---------------- +-----------------------------------------------------------------------------------------------EDEFDALVFGCGDAV-PVFQYNQDMLAVIKAFGDKGKMMIGHCAAALMFEIA-------GVAKGKKVAVHPLAKPA-------------------IQ--SGLAT------DEKSEIDGNFYTAQCENAIWTM---------------- +-----------------------------------------------------------------------------------------------ADEFDALLFSCGDAV-PVFDYNIDLLSVVREFSDKNKLMIGHCAASLIFEIA-------GITEGKRLAVHPLAKPA-------------------IQ--KGIAT------NDAVTIDGNFYTAQDEHAIPQL---------------- +-----------------------------------------------------------------------------------------------EEEYDALVFACGDAV-PVFPWNRDLMEVLKTFGETGKPMIGHCAAGMMFGFA-------GVAAGRRVAVHPMAKAA-------------------VT--GPVAT------DAPFEIDGNFFTAQEEHAIPAM---------------- +-----------------------------------------------------------------------------------------------SDHYDALVFSCGDAV-PVFSFNLDLLTVIQEFAGKHKIMAGHCAAGLIFEMA-------GITEGKKLAVHPLAKPA-------------------IQ--KGIAT------DEVVMIDDHFYTAQCEHTLPNL---------------- +-----------------------------------------------------------------------------------------------SDHYDALVFSCGDAV-PVFSFNLDLLTVIQEFAGKHKIMAGHCAAGLIFEMA-------GITEGKKLAVHPLAKPA-------------------IQ--KGIAT------DEAVMIDDHFYTAQCEHTLPNL---------------- +-----------------------------------------------------------------------------------------------ESEYDALVFACGDAM-PKFPENQDMLAVIKVFGDKGKVIVGHCAGALLFDSA-------GIATGKRVALHPYIKAA-------------------VK--SAIGT------DEPSVVDGNIYTAQTENTLCAL---------------- +-----------------------------------------------------------------------------------------------ADEYDALVFACGDAI-PVFPFNIDMLAVIKEFAEHKKLMIGHCAAALLFEIA-------GITEGRKLAVHPLAKPA-------------------IQ--KGIPT------DEAFTIDGNFYTAQCEHSISSF---------------- +-----------------------------------------------------------------------------------------------EDEYDAMVFACGDAV-PVFQYNIDLMDVIKNFGEKGKIMIGHCAAAMLFDFT-------GITEGKKLAVHPLAKPA-------------------IS--KGQAT------DEDSVVDGNFFTAKEEHYICTM---------------- +-----------------------------------------------------------------------------------------------EDEFDAVVFSCGDAV-PVFPYNIDLMSVLKAFGEKGKILIGHCAAGMLFDFA-------GVTEGKKLAVHPLAKPA-------------------IT--KGQAT------DDKSVVDGNLFTAQDEKFVWTM---------------- +-----------------------------------------------------------------------------------------------SDDFDALVFSCGDAV-PVFEYNVVLLDVIREFAQADKLMIGHCAAALMFEIA-------GITKGKRLAVHPLAKPA-------------------IQ--HGVAT------DEPYEIDGKFYTAQCEHTLPAL---------------- +-----------------------------------------------------------------------------------------------AADYDALVFSCGDAV-PVFPYNQLLIQVIKEFGAADKLLIGHCGAGVFFDIA-------GVDSGKQIACHPYVKDT-------------------IK--NGSYT------AAPCIVDGNIYTAAEEKELHLL---------------- +-----------------------------------------------------------------------------------------------EDDFDALVFACGDAV-PVFPYNVDLMSVLKAFAGKGKILIGHCAAGLLFDFA-------GITEGKRLAVHPLAKPA-------------------VS--KGMAT------DEKSVVDGNFYTAQSENFVWTM---------------- +-----------------------------------------------------------------------------------------------ADEYDALVFSCGDAI-PVFAPYVAMMQVIKEFAEKGKLMAGHCAAALMFEIA-------GVTEGKRLALHPMVKSA-------------------IS--KGIAT------DAAYEIDGNFFTAQCEHTLPSM---------------- +-----------------------------------------------------------------------------------------------AHEYDALVFSCGDAV-PVFAHNVALMQVIKEFAEEGKLIIGHCAAALIFEIA-------GITEGVRLAVHPLAKPA-------------------IC--KGIAT------DSAYEIDRNFFTAQNEHTLPSL---------------- +-----------------------------------------------------------------------------------------------EDEFDALVFSCGDAV-PVFPYNVDLMQVIKTFGDKGKMMIGHCASAMMFDFT-------GITKGKKVAVHPLAKSA-------------------IQ--NGTAT------DEKSEIDGNFFTAQNENTIWTM---------------- +-----------------------------------------------------------------------------------------------EDQFDALVFACGDAV-PVFPYNVDLMEVIKTFGEKGKMMIGHCAGAMMFDFV-------GITAGRKLAVHPLAKAA-------------------IR--NGVVT------DEKSEIDGNFYTAQDENSVWTM---------------- +-----------------------------------------------------------------------------------------------EDEYDALVFACGDAI-PVFAYNVNLLEVIKTFGERGKLMIGHCAGAMMFDLT-------GITQGKKVAVHPLGKAA-------------------IR--NGIAT------DNKSEVDGNFFTAQEENTIWTM---------------- +-----------------------------------------------------------------------------------------------EAEYDGAVFACGDAI-KEFAEYKDMFEVIAKFNELNKKLAGHCAAGLVFEIA-------GVIKDKKVALHPYAKAA-------------------VN--SGIAT------DNSSMISQNVFTAKTEESAMEM---------------- +-----------------------------------------------------------------------------------------------EDEYDALVFACGDAI-PVFQYNLDLMEVIKTFGNKGKLMIGHCAAAMMFDFT-------GITNGKKIAVHPLAKPA-------------------IQ--NGTAT------DEKSEIDGNFYTAQDENTIWTM---------------- +-----------------------------------------------------------------------------------------------EDEFDALVFACGDAV-PVFAYNVDLMEVIKAFGEKGKLMIGHCAAAMMFNFT-------GITAGKRLAVHPLAKPA-------------------IQ--TGQAT------DGKSEIDGNFYTAQDENTLWTM---------------- +-----------------------------------------------------------------------------------------------EDDFDAMVFSCGDAI-PQFSYNQDLMAVIAAFGQKEKIMIGHCAGAMLFDMA-------GAINGKMVAVHPLAKPA-------------------IQ--GGKAT------DNKSEIDGNIYTAQDENSIWTM---------------- +----------------------------LDAIGPYEALRLPGVSVTFVSDKLGLVVDEG----------------------RFKIEASASFEDL--PNPDILLVPGGTPKLLPL-DHKPLLDYIRKAHECTTFTTSVCTGALILGAA-------GLLKGVKATTHWAAYP-------------------QLKEYGAKVTS------QRYIKQGKIVTAAGVSSGIDMA--------------- +-----------------------PGFQALDAFGPLDILLEQEIQLSIIGPTMDPVSTKSPIP-NFYTT---------TSTSHQSVVPTHTYDA-PPENIDVMIVPGGFGT-RHETIKPT-VQFLIERYPRIRYLLTVCTGSYVAAQA-------GILDGKKATTNKIRFD---------------LVA---AKAHVNWVR-----QARWVVDGNIWTSSGV---------------------- +-----------------------PGFQALDAFGPLDILLEKEIKLSLIGPTMDPVSTKSPIP-NTYST---------SSTSYQSVVPTHTYDA-PPEDIDVIIVPGGVGS-RHETIKPT-VQFLAERYPRVRYLLTVCTGSYVAAQS-------GILDGKKATTNKIRYD---------------AVV---AKAKVNWVR-----QARWVVDGNIWTSSGV---------------------- +-----------------------PSFTSLDAFGPLNVLLQHNMTLQMVSADMRPVSVDRTII-DGVVGGMGA--SSASPYFTEYVLPDATFEN-AT-RPDVIIIPGGAGT-RNLNTQPA-VDWVRSQMGWPTNVMTVCTGTALLART-------HQIGGKNATSNKAAFN---------------WVRT-QDGADVNWIA-----RARWVVDGKLWTSSGV---------------------- +-----------------------PALTALDVFGPLNALIQHPMTLSLLSTDLKPVSIDRTII-DGVYQGTS---TWLSQYFSEFVLPTNTFDD-DL-DLDVIMVPGGAGT-RNLNTQPH-VDWLKARVD---YMMTVCTV---------------------------------------------------DGADVNWIA-----KARWVVDGNLWTSSGV---------------------- +-----------------------PALTALDLFGPLQALINYNMTLSLIASSLDPLSIDRTIL-DGVSQGMLG--SSASPYFAQFVLPTHTFAD-AP-ALDVILVPGGAGT-RNLNTQPA-VDWLRARMD---YMMTVCTGASVLART-------GKMEGRNATTNKAAFN---------------WVKS-VEHAKVNWIA-----KARWVVDGNLWTSSGV---------------------- +-----------------------PQFTSLDVFGPLGAMLRFPMSISVLSHNMDPVSIDRNII-NGVSVGDRA--NTASPYFTEYVLPTHTFDN-AP-EFDVLFVPGGSGT-RNNTTQPA-VDWMTRVLGWPQYVLSVCTGAALLART-------GKFGGKNATTNKAAFN---------------WVRS-VQGADINWIA-----RARWVVDGKLWSSSGV---------------------- +-----------------------------------------------------------------------------------------------PEDYAALVLIGGFGWM--NSEAERVLPIVKDALSKGVVVGAICNAASWMAK-------QGLLNNIKHTGNGINQL---------------------KLWGNNYTNETGYVNEQAVTDGRIVTANGSGY-------------------- +------------------------------------------------------------------------------------------------PSYDAVS--GLEG-SERFCKSEVVGAVLKQHESSGKIIAAICA-------------------GKRITSYPGTKDKITP--------------------DYTYVE-----GERVVIDGNVVTSR------------------------ +------------------------QASILEVASTLDPLRAELYRWRVVSPNGQAVPCGIELPSH------------------------GPLT--AAEGADALVVIAGFQQWQG-A-TQPLIRDLARMAPRFAAMGGIDAGSWVLARA-------GLLNGYKATVHWEDLE------------------------------------------------------------------------- +------------------------GTKALTLALAEEALRVVVYELSFLQAEAGEPTAGAWQLPG------------------------EPWTG-RLDGFQKLFLLA-DEPPAA-V-APALGSALKQLVRAGCSIGGLSAGVYPLAQL-------GLLDGYRAAVHWRWQD------------------------------------------------------------------------- +------------------------NFTLISLASAVEPLRMELYRWTTLSVDGSQVWDGLQITPD------------------------AAMH--KAPALDTVIVCGGVGIQRT-V-TREHVSWLQSQARQSRRLGAVCTGSWALACA-------GLLDGFDCSVHWECLA------------------------------------------------------------------------- +------------------------NFSMIAFTNAVEVLRMQHYRWSILTPDGVPVRNGIAVKPA------------------------RTLE--EAGRPDVLIVCGGTGIRSA-V-DNSVRALLEDVAQQGLPLGGICTGAYALMSA-------GLLDDYRCTADWEGLS------------------------------------------------------------------------- +-----------------------NGSEEIEVVTLIDILRRAKVNVVVASVEKSAQV----LA-S------------KGT----KIVADKLINATSDSIFDLIILPGGAAGAERLHKSKILKKLLKEQESAGRIFGAICSSPAVLQK-------QGLIKDKKATAHPAVLDKL----------------------------------------------------------------------- +--------------------------------------------------------------------------------------NIQDLAELKVSEFDAVIFPGGFGVAKNLCVNEHVKSTLQAFHSAKKPIGLCCISPVLAA---------KVFPGCEVTV------------------------------------------------------------------------------- +-----------------------EGFQALDVFGPLDALLDNGIKLSIIGPDLSPVSKPPSSTANL----------KPGWGFSESVAPTHTYAN-PPTDIDVLIVPGGMGTN-DATNVMPAVQLTRNLYPNVKYLFSICTGAKILAAA-------GLLDGKQATTNKRHYEIAIK------PYP-----------QVKWQR-----SARWVVDGNIWTSSGI---------------------- +-----------------------DGFDELDAIAPFEVLSAAGFDCELVVLAGEHDPAPVTATHG--------------------LR---VLPDELAAAPDVLLVPGGGWATWAEHERGVLPAAIAARHAAGSVIASVCTGAMLLARA-------GLLEGRPAVTHRIALA-------------------DLAAAGADIRP-----HERVVDDGDVVTGGGVTSGLDVALRLVE---------- +-----------------------------------------------------------------------------------------------LSQFDAVYVPAGP--HWVILFSSVTHDLLASAYEAGLVVSGICIGTIALAQV------SSVVSGVKIAYYDTTAA-------------------DMMDAGATIVY-----GSGVVSDKRVVTAGS----------------------- +-----------------------YGFHPDHVSIPYHYFTDAGVRITFATPNGHTPMADLLVLNGYLNKLHKAYYTV--MTQHQSFQNPIAYKDIASDQLDAILIPGIR--------------------------------------------------------------------------------------------------------------------------------------- +------------------------------------------------------------------------------------------------PPIDVLVVPGGLG-WKQVIDDPAIREWLRTAAADARAILAISTGSLLLASV-------GRLEGREATGH-------------------WLAEDELAALGATVRSSR-----TASDDGRVVTASGALAAIPVI--------------- +-----------------------PGFEVLDVFGPVEMWNTPGLEVVMISQDGGPVR---SAQGAVV----Q-----ADYS----------FAT--APKLAIMMVPGGAGT-YGQLENPALMAFLKARDAETEFTTSVCTGSALLAKA-------GLLKGRKATSNK----------------------------------------------------------------------------- +------------------------GTEIHEASAILVHLSRGGAEVQIFAPDVPQHVIDHTKQPSE--GETRNVLTESGRIARGK---ITSLAELRAANHDAAIFPGGFGAAKNLNVNKDVERVLKEFHKAGKPIGLCCIAPVLAA---------KVLRGVEVTVGHEQEEGGKW---------PYGTAEAIKALGAKHC-------------------------------------------- +------------------------GTELHEASAVLVHLSRGGAEVQIFAPDVPQHVIDHTKQPSE--SESRNVLTESARIARGK---ITDLAQLSAANHDAAIFPGGFGAAKNLKVNRDVERVLKEFHTAGKPIGLCCIAPVLAA---------KVLRGVEVTVGHEQEEGGKW---------PYGTAEAIKALGAKHH-------------------------------------------- +------------------------GSEIHEASAILVHLSRGGAEVQIFAPDVRQHVVDHTKQPSE--SESRNVLTESARIARGK---ISDLAQLNAANHDAAIFPGGFGAAKNLRVNQDVERVLKEFHGAGKPIGLCCIAPVLAA---------KVLRGVEVTVGHEQEEGGKW---------PYGTAEAIKALGAKHC-------------------------------------------- +------------------------GTEIHEASAILVHLSRGGAEVQIFAPDMPQHVIDHTKQPCE--TETRNVLAESARIARGK---ISDLAQLSSKNHDAVIFPGGFGAAKNLKVNHDVERVLSEFHRAGKPIGLCCISPVLAA---------KVLHGPEVTVGHEQEEGGKW---------PYGTAEAIKALGAKHQ-------------------------------------------- +------------------------GTEIHEASAILVHLSRGGAEVQIFAPDVAQHVIDHTRQPSE--NESRNVLAESARIARGK---ISSLAQLSAANHDAAIFPGGFGAAKNLRVNEDVARVLKEFHAAGKPIGLCCIAPVLAA---------KVLSGVEVTVGHEQEEGGKW---------PYGTAEAIKALGAKHC-------------------------------------------- +---------------------------ALDLIGPYEVLRMPDAEVRFVTHEAGPVVADSGVL---------------------LIGATHSFDET--PSPDLILVPGGPG-CFGAAKDEKLLDWLRAVSPGAQWTTSVCTGSVVLAAA-------GLLDGLRATTHWSS--------------------------------------------------------------------------- +------------------------DFTDIDVFLMWDLLEHTDWRVQILGDKAEH----TSVT-----GI--------------RIPMHGLLDEA--NSSDAVLFTSGKG-TRVKMRDAEFLSA-FRLDEERQLIGSICSGALLVAAL-------GFLEGRRATTYPTAV-------------------------------------------------------------------------- +------------------------NFTDIDVFLPWDLLRLSDWDVQLLGTEETH----ISMS-----GL--------------RIPMTGSISDI--PFADAVIFASGKG-VKDLYKNQQYINS-IHVDPQRQLIGSMCSGSLLLGGK-------KLLTGKKSYYISLSS-------------------------------------------------------------------------- +------------------------DFTDIDVWLMWDLLGREDWQVRILAEKEEV----TSST-----GI--------------KFRVHGLLSEA--RESDAVLFASGKE-TRRVIQDKSFLKS-LNLDAEKQLIGSMCSGALILAAL-------GLLDGKKATTYPTAK-------------------------------------------------------------------------- +------------------------GFNELDSFIASAILKDHGWNVQITCPTKSV----TSMN-----GL--------------EIVAQRPLEFA--NKADAVLFGSGML-TRQIAQDEAILSR-FSLDSSKQVIGAQCSGTLLLSAL-------GLLNDVPACTDLTTK-------------------------------------------------------------------------- +------------------------GFNELDSLIALGILKKPGWRVSIASPTPKV----ESMN-----GL--------------IIERHIPISEV--SFADAVIVGSGIK-TRQIRADPELMKQ-LQLDPSRQLLAAQCSGALILAKL-------GLLDTIPACTDLTTK-------------------------------------------------------------------------- +------------------------GFNELDSLIALGILKKPGWRVSIASPSARV----RSMN-----GV--------------VLEAQASLREA--SAADAVIVGSGMQ-TREVVADAALMAQ-LQLDPSRQLLGAQCSGTLVLAKL-------GLLDGVPACTDLMSK-------------------------------------------------------------------------- +------------------------GFNELDSFIAAAILKPQGWAAYITAPDETV----TSMN-----GV--------------TVQRQRPLDFA--AQADAVLVGSGIR-TREIAADAAMLDR-IALDPARQLIGAQCSGTLLLAKL-------GLVGDLPACTDLTTK-------------------------------------------------------------------------- +------------------------GFGELVSFAPFEVLIPFTVELVSSEQKREV----TTSF-----GV--------------TVKLHDFLRMD--NRPDLLIVPGGGW-NHKAKHGAAEIGTLSEMHNVGTIVAGVCTGGMLLAAA-------GILNGKKATMHHLA--------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------------------MPGGMTT-VEHARDEKLLQWLRRAHQTAAWTASVCSGSIILASA-------GLLHGKRATSHWMALS-------------------ALKALGAIPVD-----NERIVQEGDVVTCAGVS--------------------- +-------------------------------------------------------------------------------------------------------MPGGLTT-FEHARDEKVLAWLRRTHESSRWTTSVCSGSVLLAAA-------GLLRGRRATSHWMALP-------------------MLRPFGVHPVG-----DRRIVADGRIVTAAGVS--------------------- +----------------------------------------------------------------------------------------------------------------MAARDDKLLDWLRRVHPAAAWTTSVCSGSLVLAAA-------GLLEGQRATSHWSTLP-------------------LLKPFGVTPVG-----DERIVRTGHLVTAAGVS--------------------- +----------------------HDGVEILDFAGPSEVFATEGFQVYTVSLTKDPII-----SQGFV-----------------KIVPTYDLTD--CPQPDIVVLPGGKTG--PFINNKPLIDWIKRSSERAEVMLSVCTGAGLLAKA-------GLLDGKQATTFHSYIE------------------------------------------------------------------------- +------------------------GVRSLTFSGPADVLGEEGFRHDLTAPEGTPVRASSGLA----------------------LVPDTSLADVP-------------------EVGRETADVIAALSARPRRLASVCAGAFLRAGT-------GLLDGRTAATRRQHARE------------------------------------------------------------------------ +------------------------GVQSLDVTGPVEVFARCRPAVRTVSPGGGPVRTGSGLN----------------------LLPDGDLESARPGPGTTLL---VPGGRFTGDFEPRITDWLRAYGGRAGRLVSVCTGGLLLAEA-------GLLDGRRATTHWAASER------------------------------------------------------------------------ +------------------------DVEVLDFAGPFEVFKVHEETVYTVSQNGEMITARNGLK----------------------VKPDYSIEDLPPVDILIIPG--GKGARENEVKNDIIINWVRQQMKEVKLMTSVCTGALLLAKA-------GLLEGLKATTHWASIQT------------------------------------------------------------------------ +------------------------GMKLLDLSGPAEVFNRFGARLSIVSADGSPVRSSIGML----------------------VPADTDARAAAAHDTLVVV---GGDALPGSPVGPVLGAAAKELAERAGRVASVCTGAFVLGAA-------GLLEGRRATTHWQHTAT------------------------------------------------------------------------ +------------------------QCLLLDFAGPLQAFCETSQVWQTCSLKGGPVKTSSGLE----------------------VMTSALAD-CDLRNIDTLIV-GGGPGVHRAAAEAALIDWFRLAAPKARRVCSVCTGTFVLAAA-------GLLRGRRAVTHWGS--------------------------------------------------------------------------- +------------------------LTEAFELGVACEVFRSDDGDFSLVAGSPEPIRTRFGYG----------------------IDVPYDLDRLDDADLIVVPAGTFVCAKDPDPCMDPLLDKLRAAVDRGAKVASLCSGAFVLGAA-------GLLDGRTCTTHWRHAQR------------------------------------------------------------------------ +------------------------RVHLLDLAGPAQVFAALGSELCFIKDGEQPISSAQGLA----------------------LAPESKWPDLSVTDLILVPGGSAPEVKSASILSSASLQRLSEHGSRGGRVASVCSGAISLGLA-------GLLDGRRCTTHHELQQG------------------------------------------------------------------------ +------------------------QLCTFEFGCTVEVFRPELGEFATFPVDDGPITAAGGIT----------------------IVPTPGEVLLENADTIIVP----GWRGVESEVPQRLIEQLQAAHARGARICSICTGAFVLAAA-------GLLDGHKVTTHWRYTDL------------------------------------------------------------------------ +------------------------GFDELDAVGPFEVFARAGATVSLITAERSPAASGASLH----------------------DVDRTLADPESADAPDLLVVPSGEGGVRREYDAGDLPPRIAAHHEAGATIASVCTGAMLLERA-------GVLGDGPAITHQSAVED------------------------------------------------------------------------ +---------------------------------------PQSYNVEIVTTDGAPITS---SS-----N---------------SIVVADNSLS--DKPYDLVIIPPIEGSKSMPSSSILIIEWLIPKINSSTSILSLSTGSYFLAAT-------GELNKTAIATHWSLIKPLSK---LFP--------------DCQFIN-----HKSYLKMGSIYTTGSFEAGISV---------------- +---------------------------------------AESYQVEILSLDGLAKTS---AS-----GP--------------SIEVDDKVRM--ESTYDLVILPSFEGNRQIQEENNDLVDWLTSQIQQQTPILALTTAAYFLAAT-------QQLQHVLLATHWAFLRELKR---LFP--------------QSSFTA-----NRNYLQSEQIYTTGTLLGTFDA---------------- +---------------------------------------VATYQVEILSIDGLAKQS---AS-----GT--------------QIDVNGHIML--DRIYDLVIIPSFEGKQTLTLQSHDLVLWIRRLIQQQIAILAVTTGVYFIAAT-------KLADHILLATHWAFIRELNG---LFP--------------SCSFTK-----NRNYLYAGSIYSTGTLMGTFDA---------------- +---------------------------------------AESYQVEMISLDGLAKTS---AS-----GP--------------SIEVDDKVRR--ETTYDLVILPSFEGNRQIQEENDDLVDWLTSQIQQQTPILALTTAAYFLAAT-------QQLQHVLLATHWAFLRELKR---LFP--------------QSSFTA-----NRNYLQSEQIYTTGTLLGTFDA---------------- +---------------------------------------ARGYRVRVLSADGARIAL---AS-----GH--------------VIQPDAALEE--LGAGDLIVIPPIEGPRAGFSPDPRALEWLARSREQGARILAMTTGVCYLAAA-------GLGQGLL-ATHWAFVRPLKL---RYP--------------AWDFSA-----HPSFLQAQGIWSSGSLGGGFDA---------------- +---------------------------------------ERSFAVRVVSVEGAPVLA---AG-----GH--------------LVTPDGGLRD--VAEASLIVLPAIEGPRAGFEPDARVLAWLGERIDAGARVLALTTGAAWLAAS-------GRLDGGLLATHWAFVRQLGK---QYP--------------ACRFVA-----RESFLQEGGRYSTGSLNGCFDA---------------- +---------------------------------------EPSFRVRILASAREVT-F---AS-----GH--------------SLRADAILEI--DADCDLLVIPAIEGARAGFVPDAASLAWIAQRIDAGARVLALTTGAAWLAAS-------RRADGLLLASHWAYVRQLAR---RYP--------------QCRFIG-----QRSYLQADGLYTTGSLGGCFDA---------------- +---------------------------------------AAAYRVHLLANAADRLDA---AG-----GI--------------GIETDSPLEE--SRPVDWLIFPAIEGPVHTPSPTRRGLAYLARHCEAKRVVLTLSTGIVPLAAT-------GLVNGLCINTHWAFLPTLQQ---RYT--------------ECHFRA-----RESYLQDRWLYSTGSLHGSFDA---------------- +---------------------------------------APGYAVEVLSGDGAEVRA---AS-----GH--------------RVQADGAIDA--AQCYELVVIPAIEGVRAGFSPDARLVAWLAAQHRAGARVLALTTGVCFVAAA-------GLAEGLLMATHWAYVRQLKK---RYP--------------GGQFVA-----HQSCLQASAIWSTGSLNGAYDA---------------- +---------------------------------------APPPIINIVTQDNQPVVG---IG-----GV--------------VVQPTIDIQA--VKQTDILLVGSVGFPDNLASVTQPTLDWIHQWGECDIPIVSICSGAFVLAKA-------NLLHNAKATTHWFYANLFRE---LFP--------------QTKLYA-----ERRVTCDNNRFCTSGVYEYNDV---------------- +---------------------------------------EQRMDMQLVSPSGAAVSC---LG-----GL--------------KLSVHDKLKP--QQTPDLIVIGAIGHPERPKDFDPEILGWLRQKHAQGSKIASICTGAFVLAAS-------GLLDDLPATTHWQCASLFQQ---RFP--------------KVRLCS-----EAMITQQNGLYCSAGASAYQDM---------------- +---------------------------------------APEPVIHIVTQDNQPIRG---LG-----GV--------------IISPTIDIEK--VRQTDILLVGSLGFPDNLETLEDATLDWLKQFESHDIPIVSICSGAFVLAKA-------KMLENRTATTHWHFANLFRD---MFP--------------NTRLQV-----DRRVTCDQKRYCTSGISGYSDV---------------- +---------------------------------------VTPPKINIITQDNNPVVA---HG-----GI--------------TLTPTVKIES--IKSTDILLIGSLGEPDELTACSEKALKWLEDFADTDIPIISISTGSFALAKA-------NLLSKRNATTHWRYANLFRD---MYP--------------GTKLRV-----ERKVTCDGNYYCTSCTNGYNDV---------------- +---------------------------------------TPLFDVKIATIDGKPVKT---YF-----GH--------------ELKPDISIQD--ADKSDTIII----PPSASDILEPKAVSWLIESYEKGAHIASICLGAFLLAQT-------GLLENKTATTHWGYMNRFRK---QFP--------------KIKLKP-----EKLITDEGDIFTAGGANAGGDL---------------- +---------------------------------------APEPEVNIITQDNQDAIG---LG-----GV--------------RLKPNKLIGE--IKQTDIVLVGSVGVPYDFDLCTQETLDWLQMMEEKNIPIVSICTGSFVLAKA-------NLLNNRKATTHWLFTNLFKD---MFP--------------QVQLHS-----EIKVTSDNNIFCTSGTYEYNDV---------------- +---------------------------------------GPMPDVRIVYPTQKGV-------------DKP---------HDLLIGFQGSLYY--GTQPDLILIGSLGFPEQPHHCSQEIIDWLKAMDEKHIPIVSICSGTFMSANA-------GLLKT-SATIHPHFAAEFKE---LFP--------------HIPLYT-----DKKITCDNNRFCISSAYEDARC---------------- +---------------------------------------FQGFMTHVVTPNNRPLIG---RG-----GI--------------SVQPTAQWQS--FDFTNILIIGSIGDPLSLDNIDPALFDWIRELHLKGSKIVAIDTGIFVVAKA-------GLLQQNKAVMHSYFAHLFGE---LFP--------------EIMLMT-----EQKALIDGNVYLSSGPYSHSSV---------------- +---------------------------------------YKKLNIQLVSNDGHAIDC---VL-----GA--------------TIP------Q--TPLQDYVFTPSIWNPRPVVKTSSQTIDWLNNQWHKGATIIGVGTGVCLLSES-------KLLDGHSATTHWHYASQFKR---DYP--------------SVNLKP-----DYFITQSERIYTVASLNALADV---------------- +---------------------------------------CRALSIELLSHNREPVTA---HS-----GL--------------PFFPSRNYDD--ISHCDLLILPSLWNPRPVLRQQNALVTALRAMNCKHTAMIGVGTGNCFLAEA-------GLLDGHPATTHWHYAAQFKR---DYP--------------KVDLKP-----EYFITQAEGLYSVASLNALADV---------------- +---------------------------------------FRPLAINLVAKSAESIPT---RA-----GL--------------AINPDCITTN--APYSDLIIVPGIWNPRPVVRTNQEIVDWLSESFSAGSHIIGVGTGNCLLAEA-------GLLDGHPATTHWHYAKQFSH---DYP--------------QVHLKP-----DFFITQSERMYTVASLNALADV---------------- +---------------------------------------FKPLNINLVASSLKAIPN---RT-----GL--------------SIMPDCETVT--APASDLIIVPGIWNPRPVVSNQQSLVNWLGNSWQQGSHIIGVGTGNCLVAEA-------GLLDGHPATTHWHYAEQFKR---DYP--------------KVQLKP-----DFFITQSERMYTVASLNALADV---------------- +---------------------------------------FPAPLVSYVSVTGGPTQF---LG-----GL--------------TINCYTHWES--VEHTDILLIGACGDVSESYFLLEDVKCWLKKQIIQCEFVLSLCTGAFLLAEL-------GVLNKRSATTHWVYAERFRE---QFP--------------QVKFKP-----HLKITHEGKYICTSGIKEYFSA---------------- +---------------------------------------HPAPEISYVSPHQGPIAS---FA-----GF--------------TLSNITHWST--VNDADIVLIGSCGEPDRSYQLPDDMKQWLKKQIAQCKYVICMCTGAFLLAEL-------GVLNRRSATTHWVQVERFRH---LYP--------------DVKLMP-----HRNVTHDGPFICTSGIREYYEA---------------- +---------------------------------------LPDPDVRYISPYDAHIHT---FS-----GL--------------TIACPTPWQQ--VEKTDIFLLGCCGDPSEAYLLPDKLKTWLTQQLVGSQFVVSLCTGTFLLAEL-------GLLNHRSATTHWAHVAGFRE---RYP--------------SVKLMP-----HLKITHEGPFICSSSVRDYYDA---------------- +---------------------------------------IPEPKINLVSTSGNNVQA---LG-----GI--------------RLSPNRDWSE--ISDTDVLLIGSCGEPELPLLMSDEMGNWLKKLISETSYVVSLYTGAFILAHL-------NVLNRKTATTHWVHSRLFRD---LYP--------------KVKLQP-----HIKITREDNLICTSSVVEYYQA---------------- +---------------------------------------LSPPEITIVTVDDSDVQG---IG-----GL--------------TLHPTSKITD--VKDTDILLISAIGDPNHIDKCTNATFEWINSLSKQAQFTISICTGAFLLARA-------GVLNYRTATTHWMYTDLFRD---NYP--------------KATLVT-----DQCFTQDNNVLCTSGIHSHDKA---------------- +---------------------------------------CSSFSSTVVSVDNKPISG---RG-----GI--------------TIQVDERWQN--ITAADVLLVGSIGDPEILNCIPQEIIEWVKSLHQKGTRVVGIDTGVFVLAQG-------GLLDGSEAVVHPYYSQLFRK---NFP--------------AISLLE-----QRKALINERVYLSSGVYTYQGL---------------- +---------------------------------------CRGFASTVVSADNKPISG---SG-----SI--------------SIQVDERWQN--INAADVLLVGSIGDPETLDCIPKEVIEWVKKLYQNGARVVGIETGIFVLAQG-------GLLDDCDAIMHPYFSHLFRK---KFP--------------GISLLE-----HRKTLINDRVYLSSGVYTYQGL---------------- +---------------------------------------GAAPHVSIISPPHQEN-------------RNHT--------NNLLMGLAASLDC--GQQPDMILVGSLGFPEETRHCTPEIIAWIQAMDEKRIPIVSICSGTFILAQA-------GLLNN-GATIHPHFFPEFKK---RFP--------------HIPLYT-----DKKIISDNHRFCISSAYGCGSC---------------- +---------------------------------------SAAPHVNVIFPANPHM-------------MDGA--------NDLFADLHDSLHY--RRQPDIILIGSLGFPEGSQHCSQEMIAWLKAMDEKNVPIVSICSGTFLLAKA-------GLLQT-GATIHPHFSAEFQQ---LFP--------------HIPLYC-----DKNVINDNHRFCISNVYSGGSC---------------- +---------------------------------------NSVPHVSIISPASSQL-------------NDT---------HGLFIERNALHLE--GQKPDIILIGSLGFPEEPQHCSQEIIEWLRAMDEKHIPIVSICSGVFMLAKA-------GLLQA-GATIHPHFAAEFKN---LFP--------------HIPLYT-----DKKIISDNHRFCISNAYGSGSC---------------- +---------------------------------------GPIPHVRIISPANQEM-------------SGT---------NRLLTESHSDLYH--GQQPDIILVGSLGFPVQPQYCSPEIIEWLKAMDKKHIPIVSVCSGTFILAKA-------GLLKT-SATIHPHFSREFKD---LFP--------------HISLYT-----DKKITRDNNRFCISSAYGCSKS---------------- +---------------------------------------GPIPHVNIISPTQQGMIG---QG-----MTHQSVN----NTNGLFGDLNNYLQD--AQEPDIILVGSLGFPEEPRHCSREIIEWLKAMDEKHIPIVSICSGTFMLAKA-------GLLNT-GATIHPHFSTEFKK---IFP--------------HIPLYT-----DEKIISDNHRFCISSAYGCGSA---------------- +---------------------------------------VLKLNTQFLSESSTSIKS---RA-----GI--------------TMVADITLDD--SGTPDIIIVPSLWNPRPVLKKHPKLVAWLKLCWQRGSTLIGVGTGVCFLAES-------GLLNNHSATTHWHYVEQFKR---DYP--------------QVDLKP-----DFFITQSERIYCAASLNALADI---------------- +---------------------------------------FIPLEIAWLSESGEAVLS---SM-----GV--------------PFSAHTSFSA--LSDFDYIIIPSIWNPRPVLRKNASLVSNLAQARRSGATLIGVGTGVCFLAES-------GILDGHSATTHWHYAEQFKR---NYP--------------LVALRP-----DYFITQSERLYTVASLNALADV---------------- +---------------------------------------AASLNIQLVSQDNQEIAS---RA-----GI--------------KLTPDARLQD--CPTPDIVIVPSLWNPRPVLRQQQELIQWLHDLWQQGTTLIGTGTGVCFLAQS-------GLLDNHPATTHWHYVEQFKR---DYP--------------AVVLKP-----DFFITQSERIYCAASLNALADI---------------- +---------------------------------------VLKLDTQFLSESSVKIKS---RA-----GI--------------TMVADITLDK--STPPDIIIVPSLWNPRPVLKSHEKLVAWLKHCWQQGSTLIGVGTGVCFLAES-------GLLDNHSATTHWHYVEQFKR---DYP--------------QVDLKP-----DFFITQSERIYCAASLNALADI---------------- +---------------------------------------AANLSIQLVGESNKKIAS---RA-----GL--------------AIYPDVTVEH--ADVPDIVIVPSLWNPRPVLRQNPQLIAWLAERWQQGSTLIGVGTGICFLAES-------GLLDNHSATTHWHYVEQFQR---DYP--------------KVLLKP-----DFFITQSERIYCAASLNALADI---------------- +------------------------------------------------------------MS-----PF--------------TVKADTTIAE--VTAADLVIVSPIDEPVAVLQENPPLFEWIRQQYAQGAEVVSLCTGAYILAAT-------GLLNGKEAASHFSVMSDLRQ---RFS--------------EVNWQK-----GAIITEKDRVITSGGALSSLNA---------------- +-----------------------------------------------------------------------------------------------------MMHQ-----------SP-GFPGLRQAFDRGVVLASVCTGSFVLAEA-------GLLADQVATTHWRAAMQFRN---RYP--------------DIRLEE-----DQLLVDNGQIICAGGATAFVDL---------------- +---------------------------------------RMETQLHILSADGGPVVL---GD-----GR--------------SFPVDGPANR--EEPMAFIWLPAFRGRERRLAEAGPLIDWLHRQSEMGAVIGASGAASTLLMAG-------GFTADLAVPVARAMQPLTRT---LFP--------------RQPFEE-----RFGLVDHGHLLIGNGMGNDLQL---------------- +---------------------------------------NRDMQLTLLSSDGGEVRL---DE-----HV--------------TVQVDRAIAS--NDRFDFVWVPSFRGGSKRLQELRPVVDWLAGLGGSGSLIGASGSAISLLVSA-------GLVRDFAFPVVPALAPTLRE---IFP--------------RAKQDD-----HREIVERGNILLSRGTACDDEL---------------- +---------------------------------------RMETRLRILSLDGGPIRM---SD-----GR--------------RLDVDGAISS--VDDHGFVWLPAFRGIPERLARSHALLPWLRQQAAGGAVIGASGASALILMAA-------GLTHDVAVPIARALQPVARA---MFP--------------RHRAEE-----RLALADHGDLLIANGMAHDLAL---------------- +---------------------------------------RMQTELRLLAAEPGPIAL---VG-----GR--------------RFAADATLAE--TDDPRFIFLPSFQDPDGLPSGFAPLHAWLREQNAKGVDIGACGASVFHLAAA-------GLLDGRAGAVGARLVPAMRR---LFP--------------RVSVDP-----DNVITHAGNIWTCSRDADSAAL---------------- +---------------------------------------KAPLRTRWLSLDGAPVRL---AS-----GA--------------ALNVDGAIGN--TASYDAVLVAAFEGARNTLGMLSPVVDWLRLQAKRETWIAACGGSIGLLADA-------GLLDGKPACVPWWLEAAFHR---RYP--------------AAALQR-----STALTHAPGVLCAGPMSAWPAL---------------- +---------------------------------------FDVVDLRLLAPGKDRPAT---EG-----GH--------------LLPMTGSLDE---TPCDVVFVADCAQADRERGHGGELGHWLKARRAEGAIIGASGEGIALLAAN-------GLLEAIKATAPVGKLAEWHM---RWP--------------RVRFEP-----GKVLIEDANIVTSQGGVYDQEL---------------- +---------------------------------------KMKTQVRLLSATAGGLEF---AG-----GR--------------KMDCDGDLLD--GAEYSIVFIPAFASEETLLDHAQPVTEWLRWQRARGAVLAASGTGVLLLAQA-------GVLDGGPAAVPNVLRGFLRS---RYP--------------KVRVAA-----GATIAEHDGVYTCAVPASEWQL---------------- +---------------------------------------TMKTQVRLLGANGNSLEF---AG-----AR--------------RMESDGNLLG--DTEYRIVYVPAFASEETLLDHAEPVTEWLRWQRARGAVLAASGTGGALLAQA-------GLLDGGPAAVPRVLRSLFRS---RFP--------------KVRVET-----GSTIAEHDGVHTCSVPASEWQL---------------- +---------------------------------------GMHTRAKLLGPTPRPIQV---LG-----GW--------------KLQVEDGL-D--ATPHLYIHVPDFY-EEEYLARLQPVIDWLRAQHAGGAQLSATGRGMELLAEA-------GLIGNGPVPVARGAAADFRG---RYP--------------HIRVNT-----TEPITEVGRIMMARGMTQEMSL---------------- +---------------------------------------RDPMVARHLSLGGTSKRA---FD-----GT--------------MIEVDGPLSG--DESYDFIFIPSMPRA-IAESDLQRIGTFLRTQHEGGAVVAAQGGGVVPVAAS-------GLLDRHAAAVFWSRAVAFRE---RFP--------------AVRPEA-----VETITFQNNVGCASTMAAGPPL---------------- +------------------------------------------------------------------------------------------------AACDVLCVPGGLGC-LDAAEDIRFIHAIRHLAGTAKFVTSVCTGSLILGAA-------GLLHGRRAACHWAWRDM-------L----P--------LFG-TIPD-----PARVVRDDEIITGGGVTAGIDFALT------------- +----SCLVVLPSCK---------EGVSAQSFIQCFT-LTHSAFTVQLATPGGKTPE--------FINDQSRRWL--N--DFTKPFAVPLSLEIIDPNRYTSLVIPHAPGAAVDLANNKDLGHIILQFIRD----------------------------------------------------------------------------------------------------------------- +-------------------------MLG-------GLLVQDRYETMTVRPKQEK----------------------------------L-P---PSDGYNLLVVLGAPYSVNDLPHLREEEGIIREFVESKRPVLGICLGSQLIAKAF----GGRVYTG------------------------------------------------------------------------------------ +ENMSDVLLVQNTRI-------EGSGYLG-------ELLKEDGFNITSVNAKHEK----------------------------------L-P---N-KDFSLVIILGAPESANDLPYLREEQQLIKNSVEKNIPVLGICLGSQLIAKTF----GSNVYSG------------------------------------------------------------------------------------ +--MSDVLVIQNARL-------EGPGTIG-------DLLKADGFKIQTIFAKKEK----------------------------------I-P---K-LNHAMVLVLGAPESANDLKYLQNEIVLIQESVRAGVPVLGICLGSQLIAKAL----GARVYPG------------------------------------------------------------------------------------ +----MITILRHGEH-------EPAGTIE-------DTLNAKNEPFTVIRLYESP----------------------------------V-P---A-DPPERLIVLGGQMSVNDFPFLVDEKSLVKKAVARGSTVFGICLGAQMIAAAC----GKTVYAG------------------------------------------------------------------------------------ +-----MTIWQNVPF-------EDEAAIK-------EWANKNNIKYNVIKCYENP----------------------------------L-------YADDLLIVLGGSMSTYDIDFIKKEIEFLENHIKEGKKVFGICLGAQLIAKAL----KAEVYSS------------------------------------------------------------------------------------ +---MKVLIIKNVVS-------EGPGTIL-------DFLKNNNISFRVVEASLGP----------------------------------I-P---SLNTFSSIVIMGGPMAVYEYPFLKDVASTIEKALKMNKKVLGICLGAQLIAYVL----GAKVYRG------------------------------------------------------------------------------------ +-------MIQNTNI-------EGLGLFE-------HLLKSDGYSIKTIQAKQEK----------------------------------I-P---T-KKYSLLIILGAPESVNDHEYLSDEIHLIQNYVEHNLPVLGVCLGSQLIAKAF----GANVHRG------------------------------------------------------------------------------------ +--MNNVLVIQNARS-------EGLGLFR-------QLLESDGYVIETIQAKQEK----------------------------------I-P---S-KRYSLLIILGAPESVNDLGYLSNEMDLIQNYVRSSIPVLGICLGSQLIAKAF----GASVYHG------------------------------------------------------------------------------------ +--MKQLLAIRNVAI-------EHAGLFE-------EVLRQKNYQISYIDAFKGL----------------------------------A-G---NLKNYSLILVLGGYMGAYEFPFLKHEYKVIEEALTLNIPLIGICLGSQMLARVL----GARVYKG------------------------------------------------------------------------------------ +---MKVVAIKHVPN-------EPMGLIE-------DILKEKGIEYEYVRVYETE----------------------------------L-P---E-VKATHIVIMGGPMGVYEYPFLSQEKEMIRQAFEDNIPILGICLGAQLIASAL----GKNVYPY------------------------------------------------------------------------------------ +GLRMSVLILKNYPS-------EGPGTIE-------DFLLKNQITYKIVEFYKE-----------------------------------C-L---DYKNCDALILMGGPMSVNDCGYLNKEEEITRYFIESGKKVLGICLGSQMIAKTL----GSKVYKG------------------------------------------------------------------------------------ +---MAVLICKNIHT-------EGPGTLE-------DFLKEKGISYTIVEMSMNQ----------------------------------I-P---DTKFFDTLVILGGPMSVNDYPYIKTEENLVKEFISQDKRILGICLGSQIIAKAL----GSKIYKG------------------------------------------------------------------------------------ +GHTNQILCIKNISI-------ETLGNMK-------SYFLSDGFKVKEILATTKA----------------------------------IRSQ--NLPEYDAVFILGGPMSVNDLDYLLEEKKLIHSSFDLGIPIFGICLGSQLIASSC----GGNVYPG------------------------------------------------------------------------------------ +--MSEVLIIQHQAM-------EGPGTIE-------EEIVKAGHKVRKVRIDQGP----------------------------------V-PS--EAGSLAGIVVMGGTMSVADLKHLKEEIGLLKQFVQAEKPVMGICLGAQLLAAAV----GAEVAAG------------------------------------------------------------------------------------ +---MKFLVLQHAPH-------ESPGRYA-------ELAIKMGVQLETVELWKGM----------------------------------L-PGRAAYGKYDAAIIMGGPQGINDYPNRDGEIDFIRR---FDKPVLGHCLGSQLIAYAL----GGNVYRD------------------------------------------------------------------------------------ +---MKFICLQHAWF-------DNAGYLE-------EWAKQWDIPLEYIDAKKPD----------------------------------Y-P---VLDQDDVLVILGGPMSVKDIDWLQDELFFIKKVISNKQKMIGICLGSQLIAHAH----GQSITTL------------------------------------------------------------------------------------ +---MKIICLQHVWY-------DNAGYLE-------EWSKAWGCELHYIDAKKPD----------------------------------Y-P---VLSGDDVLVVLGGPMSVQETEWMQKEADYIEKAINEKRKIIGICLGSQMIAHIL----GTEVSSL------------------------------------------------------------------------------------ +--MKPLLVVAHVDD-------PDLTVLG-------DVVRDHGVPIRIVRPFRGV----------------------------------L-S---APDEAAAVICLGGKESADDHDYLLRERDFLRTAAAGDVPTLGICLGSQLLALAL----GGTAVRG------------------------------------------------------------------------------------ +--MKPVLLLQHDSE-------DPPGFLG-------ELLQEHAIAFEVCDVTRSQ----------------------------------L-P---TLGDYSAVVALGGAQQAYDYPYFVEEKAWLRELVAREIPYLGLCLGGQLLASAL----GAEVRQH------------------------------------------------------------------------------------ +---MKVLAIRHVRA-------EHLGLLE-------KVLKNMSMQIFYVDTAEGR----------------------------------VQG---DLSEYSMVVVLGGYMGAYEYPFLSYEMRLMERALKEDVPLLGICLGSQMLAKVL----GGKVYKG------------------------------------------------------------------------------------ +---MRVLAIKNAKN-------EGLEYIE-------NIFEARNIEFDYVMAKEIE----------------------------------V-S---EYLDYTHFIILGGPQGVYEHPYLKKEMELIRL-VDGKKPVLGVCLGAQLIANAF----GADVYKY------------------------------------------------------------------------------------ +---MKALILRHVQI-------EHAGVFN-------DILSSKGIDIRYVDQAK-------------------------------------EL---PQEEFDILFVLGGYMGVYEYPFLSREFKIIEQFLKAKKPILGICLGAQMLAHVL----GGRVYKG------------------------------------------------------------------------------------ +---MKALAIRHVLA-------EHLGMME-------RSLRNLGFKVEYLDTAKGT----------------------------------LKE---PLEEYSLLVVLGGYMGAYEYPFLSYEFRLMEQALKLNIPILGICLGAQMLAKVL----GARVFKG------------------------------------------------------------------------------------ +---MKALAIRHVKI-------EHLGMLE-------SVLKELGFEFEYLDTAEGT----------------------------------LKR---PLEDYNLLIVLGGYMGAYEFPFLSYEYRIIERALSLATPILGICLGAQMLAKVL----GARVYRG------------------------------------------------------------------------------------ +---MRVLAIRHVEI-------EDLGMME-------DIFREKNWSFDYLDTPKGK----------------------------------LER---PLEEYSLVVLLGGYMGAYEYPFLKYEFQLIEEILKKEIPFPGICLGSQMLAKVL----GASVYRG------------------------------------------------------------------------------------ +---MKVLAVRHVKI-------EDLGMME-------DIFKEKNWSFEYLDTPEGR----------------------------------LER---PVEEYSLVVLLGGYMGAYEYPFLKYEFQLIEETLKKEIPFLGICLGSQMLARVL----GANVYRG------------------------------------------------------------------------------------ +--MRKVAAIRHVDI-------EHLGVIE-------DYLKQRGFTIEYIDTPKGK----------------------------------LKL---PVEEYSFIVILGGYMGVYEYPFLKYEFEVIEQSLKHQIPLLGICLGCQMLAKVL----GGEVYKG------------------------------------------------------------------------------------ +---MRILAIRHVKE-------EGLGYLY-------NIFSEKGFGIDICDITKNT----------------------------------SKI---DLDEYNFLIILGGYMGVYEYPFLKDEFKIVESALNKDLPIIGICLGSQILAHVL----GARVYKG------------------------------------------------------------------------------------ +---MRTLAIRHVKI-------EHLGLIE-------NYLKEKNFEIDYVDTSEGL----------------------------------LKR---ELDKYQFIVVLGGYMGAYEYPFLSYEFKIMEQALKKEIPLLGICLGCQMLAKVL----GSKIYKG------------------------------------------------------------------------------------ +--MSKVLTIRHVKI-------EHAGLLG-------EVLYNMGYKIHYLDTPKGL----------------------------------LEE---PLENYSLVLVLGGYMGAYEYPFLNYEFKIIEYSLKENIPLIGICLGSQMLARVL----GSKVYKG------------------------------------------------------------------------------------ +MSTYRVHYIQHVPY-------EGLGYIE-------KWVKDNGYSLTVTKVFEDK----------------------------------F-P---DQDDFDMLVIMGGPMGTYEYPWLKDEKLFVRKAIDSDKAVLGICLGSQIIANAL----GAAVYPN------------------------------------------------------------------------------------ +--MKRVLALQHVRE-------NPPGLVG-------EVLQENGIACKVVHVG-EA----------------------------------L-P---DPSAYDALIAFGGKQHIYDYPFSWSENALIREAVEQDLPFLGICYGSQLLAHIL----GGEVSKM------------------------------------------------------------------------------------ +LQRKTILSVQNIVC-------ETLGTLE-------QMFRDDGFEIVKINAQSDH----------------------------------V-PA--SSQGYDAIVILGGPMAVYDLPYLQRQQDLIKDAIKNNTPVLGICLGSQLIAQAA----GGRVYKG------------------------------------------------------------------------------------ +--------------------------MK-------KLFESVGFEIETKHVKKDS----------------------------------I-PQ--EVDNYAAIVILGGYMSVYQLPFLEEQQKLIRNANHHQVPLLGICLGSQLIAQAL----GGRVYKG------------------------------------------------------------------------------------ +-MKKKVLSIQNVAC-------ETLGTLE-------GMFRKDGLAVENISAQEDG----------------------------------V-PA--RSSGYSAIVVLGGPMAVYDLPYLQKEQDLIRDAIKNDVPVLGVCLGSQLIAQAA----GGRVFKG------------------------------------------------------------------------------------ +-MKDIILSIQNTEI-------ETLGNLK-------ELFESDGYTIETIHVKKDK----------------------------------I-PK--ELDKYSGIVILGGYMSVYELPYLNEELVLINNANNLHVPLLGICLGSQLIAEAL----GGRVYKG------------------------------------------------------------------------------------ +--MKPVRIFRHIAC-------EGPGYLG-------EFLDQRRVPWELVCIDVDP----------------------------------I-PP--QVEDVSGLVFLGAAVSVNDLPWLQGELELIRTAFAAGLPMMGVCFGGQLISKAL----GGEVSRG------------------------------------------------------------------------------------ +--MKPVLILQHLNT-------DGPAYLQ-------QWLQTEGLAHEVFNTEAGA----------------------------------F-PA--SLAPYGALAILGGEMSANDLPSLRRAEALFLQAVASGVPTLGHCLGGQLMARAL----GAAVVAS------------------------------------------------------------------------------------ +-MTGPILILQNLSG-------DGPGYLG-------TWLAERQIRAIVLNAERGH----------------------------------Y-PE--SIDGYAGLALLGGEMSANDLPHLRQAERLILQAMAADIPVIGHCLGGQLMARAL----GARVRTS------------------------------------------------------------------------------------ +--MRPVLILQHLAG-------DGPAYLA-------TWLARRGIPADVRCSERGA----------------------------------F-PA--DIGGYRALAVLGGAMSANDLPGLRDAERLILQAMSADRPVIGHCLGGQLMARAL----GARIAAS------------------------------------------------------------------------------------ +--MKPVLVLQHQSS-------DGPAFLA-------TWLRARGVAFEVRNAEAGA----------------------------------F-PE--STEAYAALALLGGEMSANDLSALRAGERLILDAMQRSRPVIGHCLGGQLMARAL----GARVVES------------------------------------------------------------------------------------ +--MKPIRIFSHVAC-------EHPGYLC-------EYLEKRGICYEKIHIGLGP----------------------------------I-PK--QIDNISGLVFLGSPVSVNDLPWIAEELALIKQASQAGIPVLGICFGGQLISKAL----GGEVRPA------------------------------------------------------------------------------------ +TNIRPVIVFKNVAH-------EGPGYLG-------DFLTQQNIPWQIINTNEVA----------------------------------L-PA--SILGYSGVVIMGGPMSVNDLPWIAPLLDLIREAKAADIPLLGHCLGGQLISKAF----GGVISAN------------------------------------------------------------------------------------ +--MKPVAIFRHSPT-------EGAGHFA-------QFLNQHVIPWHMIHIDQGA----------------------------------V-PA--DAGAFSGLVFMGGPMSVNDLPWIPPVLALIRDAYARDIPLLGHCLGGQLITKAL----GGVVGRN------------------------------------------------------------------------------------ +--MKPVIIFRHAAV-------EGPGFLA-------QFLDAHQIPWQLLKIDQGN----------------------------------L-PT--SIADYSGVVLMGGPMSVHDLPWIAPVLGLIREAYALDIPLLGHCLGGQLISQAL----GGQVTLN------------------------------------------------------------------------------------ +-MSKEVLIFLHMDD-------EHPGYIA-------KFLQEMKIPFRVIRSYAGL----------------------------------I-PP--WHEDMAGLVFMGGVMSANDIPWIKQEISLIRSALIQKTPLLGHCLGGQLISKAL----GATISAN------------------------------------------------------------------------------------ +--MKPVVIFRHFNS-------EGPGYFA-------DFLDAEGISWSLIKIDEGV----------------------------------V-PS--SIEAYSGMVLMGGPMSVNDLPWISPVLGLIRQAVDADVPVLGHCLGAQLMSKAL----GATVTQN------------------------------------------------------------------------------------ +--MKPVVVFRHACC-------EGAGYLG-------TFLAQHAIPWCEVRIDKGA----------------------------------V-PS--SLDAYSGIVLMGGPMSVNDLPWIPPLLSLIRHAVDQDVPLLGHCLGGQLISKAL----GGTVSKN------------------------------------------------------------------------------------ +---MKILIFQHVPH-------ESPGYIA-------DYAKEKGITLTVLELWKPT----------------------------------M-PEAA---SYDALIVLGGPMGVYDFPSKEDELRVIRDTM-GKKPLLGICLGSQLLARTL----GAKVYKN------------------------------------------------------------------------------------ +--MVKTGII-DLSL-------N-QDSYR-------DWQRDLKA-FDQINGFSGS----------------------------------Y-P---AAESYDLFLLTGSEHSILDFWWLEKLEDWIRQLIKKQVPLIGICYGHQLIARTL----SGKSSRG------------------------------------------------------------------------------------ +LSDKKVLIVSQNYH-------ETLGRVP-------RLLRQHGYAVEWLKVTEEF----------------------------------I-FD--NITQYCGVYFDGAAISANDHAWMRDQENFMKQCVDKGVPVLAICMSAGLLTRVL----GGKVSRH------------------------------------------------------------------------------------ +SHPLPVLIVLHQER-------SSPGRVG-------RLLVERGYRLDVRRPCLGI----------------------------------L-PA--TLAGHAGAVIFGGPQSAND-DYVRAEIDWIRVPLGEGKPYLGICLGAQMLARHL----GAQVAPH------------------------------------------------------------------------------------ +------------------------------------MLLQRGYSLDIRRPPLDP----------------------------------L-PD--TLAKHSGAIVFGGPMSAND-DWVKREIEWIGVPLREDVPFLGICLGAQMMVRHL----GGRVMAR------------------------------------------------------------------------------------ +--MKHILVIIHQPT-------SETGRLG-------QILTSYGYQLDIRLPSHGS----------------------------------L-PG--YLDKHDAVIVFGGSMSANDSPHIRTELNWIPLVLESKKPYLGICLGAQLLAKVL----GAKVSVH------------------------------------------------------------------------------------ +KARAKILVVLHQEH-------SSAGRVG-------HLLIENGFDLDIRRPPLGS----------------------------------L-PE--TLENHAGAVVFGGPMSAND-EFVRRETDWLAVPLSENRPFLGICLGAQMLVNHL----GGKVEGH------------------------------------------------------------------------------------ +DATPRLLLVMQAAD-------ASAGRCD-------HKLRARGYQLDYCYPQAGP----------------------------------L-PA--DMERYAGAMMFGGPMSANDRPGIRAQLDWIPRVLASERPFLGICLGAQLLARTL----GATVKPH------------------------------------------------------------------------------------ +DEASRLLLVMQTRD-------ASAGRCG-------RKLRERGYALEVCCPLAGP----------------------------------L-PA--AMDGYAGAVVFGGPMSANDLPGLRAQLDWIPQALDSGRPFLGICLGAQLLARAL----GATVQPH------------------------------------------------------------------------------------ +--MKKILIVVHQPT-------SNTGLVG-------QILRAWGYTLDIRVPSQQE----------------------------------L-PP--TMDNHEGVIIFGGPMSANDLPFIGTELDWIPVALESGKPYLGICLGAQLLACVL----GATVQPH------------------------------------------------------------------------------------ +--MKKILIILHQEQ-------STPGRVG-------VLLRQLGLELDIRRPRFGP----------------------------------L-PE--HMRDHDGAIVFGGPMSAND-TYIREEIDWLAKPLAEGKPFLGLCLGAQMLTKHL----GARVYQR------------------------------------------------------------------------------------ +SKKPRIAVVLHCQS-------SYTGRLG-------QFLKQNGFMLDLYCPIVGK----------------------------------L-PN--TLEHYAGVVILGGPMSVND-EYIREEINWISLSIKEDKPFLGICLGAQMLAQNL----GGRVCAR------------------------------------------------------------------------------------ +TSPRQILVIVHQAT-------SSPGLVG-------DKLRSQGYHLDIRCPALGR----------------------------------L-PH--TLAHHRGAIVFGGPMSANDLPFIRTELDWIALALASGKPYLGICLGAQMLARVL----GAQVAPH------------------------------------------------------------------------------------ +----------------------------------------MGYQLDICAPILGP----------------------------------L-PS--DLDDYAGVLVFGGPMSVND-AFLHQEIELIRQVLAAELPYLGICLGAQLLAKVL----GAEVGPH------------------------------------------------------------------------------------ +--MKQILIIVHQPT-------SYTGLVG-------KILRAKGYHLDIRIPSQGR----------------------------------L-PD--AIANHQGVVIFGGPMSVNDLPFIRQEIDWIQVVLASSKPFLGICLGAQMLARTL----GAEVTRH------------------------------------------------------------------------------------ +-MGKRVVLVRHGNE-------PADDRIV-------TWLGREGFEIDSRKPFDGL----------------------------------L-GE--PDEDLAGTVIYGGNFNVYEHGFLNEEYRWIEACLNADIPMLGICQGAQQIAYHL----GAWAGAP------------------------------------------------------------------------------------ +EQQPSLLIVLHQER-------STPGRVG-------QILVEKGYRLDIRRPALGD----------------------------------L-PQ--TLEKHAGAIIFGGPMSAND-DYVKAEIDWLKVPLKENKPFLGICLGAQMLSKHL----GGKVEAD------------------------------------------------------------------------------------ +RRRRPVLIVLHQET-------SSPGRVG-------QILQTMGHALDIRRPVLGP----------------------------------L-PA--TLSQHAGAVVFGGPMSAND-AYVRAEIDWLSVPLAENRPFLGICLGAQMLVKNL----GGTVFGH------------------------------------------------------------------------------------ +EVKKPVLVILHQET-------STPGRVG-------QRLMQRGYGLDIRRPRFGP----------------------------------L-PE--TLAEHSAAVVFGGPMSAND-EFMKIETDWLAVPLRENKPLIGICLGAQMLVKHL----GGQIYGE------------------------------------------------------------------------------------ +KSGNPVLIVLHQER-------SSPGRVG-------QLLLEKGLSLDIRRPVLGP----------------------------------L-PK--ALENHAGAVVFGGPMSAND-EYVRREIDWLSVPLSENKPFLGICLGAQMLVRHL----GGIVAPH------------------------------------------------------------------------------------ +SPVKRVLMVFNSAT-------GQPGRVG-------AVLRRYGYEFDIRRPGEGA----------------------------------L-PS--DMSGYHLAIVFGGPMSAND-ANVAKIMEWLPHVVNSNAMYLGICLGAQLMARHL----GAKVTSR------------------------------------------------------------------------------------ +SRSGRILIILHQET-------SSSGRVG-------QILDRMGYEADVRRPVLGP----------------------------------L-PD--HLDDHAGVVVFGGPMSAND-EGVRRETRFMDVILKSDKPYLGICLGAQILVNHL----GGRVATR------------------------------------------------------------------------------------ +KSKPRIAVVIHRQS-------TYTGRLG-------KFLQKSGFVLDIYRPILGK----------------------------------L-PN--TLEHYAGVVILGGLMSVND-AYIGEEIDWISLVLKENKPFLGICLGAQMLARNL----GGRVCTR------------------------------------------------------------------------------------ +HKKSKIAIVLHQAT-------SSAGRVG-------QILQKMGFHLDIYRPVLGK----------------------------------L-PE--TLENHAGVVIFGGPMSAND-TFILDETDWISIPLKENKPFFGICLGAQMLARHI----GGTVHGK------------------------------------------------------------------------------------ +NSKSRIAVVLHREP-------ARTGWLR-------RLLQQSGFVLDTYSPMLGK----------------------------------L-PD--TLENYAGVVILGGPMSVND-AYIRKEIDWISLSLKDNKPFLGVCLGAQMLARNL----GGRVGAR------------------------------------------------------------------------------------ +PAHRPVLVVLHQER-------SSAGRVG-------QLLVEKGFPLDIRRPALGP----------------------------------L-PD--TLSGHSGAVVFGGPMSAND-RFVHDEIDWLSVPLKENRPYLGICLGAQMLARHL----GAKVRGH------------------------------------------------------------------------------------ +--MKKILFILHKAT-------TNPGPIA-------EILSERGYQIEKRTPREGQ----------------------------------L-PL--TLDDYEAAISFGGAMSANDSPFIRAELDWISTVLSSNKPFLGICLGAQLLARVL----GATVAKH------------------------------------------------------------------------------------ +IERPKILAVLHQER-------SSTGRVG-------QLLLEAGFSLDIRRPPLGV----------------------------------L-PE--TLEDHAGAVIFGGPMSAND-EFIGRETDWLSVPLAEDKPFLGICLGAQMLSSHL----GGKVSPH------------------------------------------------------------------------------------ +RSKEPVLVVMHRRE-------SQPGAVG-------QVLRAHGHALDIRRPRFGP----------------------------------L-PA--SLDGYAGAIVFGGPMSAND-DYIRREIDWIGVPLSEGKPFLGICLGAQMLAKQL----GAEVKPH------------------------------------------------------------------------------------ +KSDPRVLVILHQHC-------SSPGRIG-------RILCDLGYSLDIRRPRFDP----------------------------------L-PK--TLADHAGVVVFGGPMSAND-DWICREIDWIGVPLKEGKPFLGICLGAQMLARHL----GHRVCPH------------------------------------------------------------------------------------ +-MPDKVLIVVHQKH-------STPGRVG-------ELLEARGYTLDRLCPCLDP----------------------------------L-PP--DPSEYAAVVVFGGPMSANDLAGIGREIDYTNRVLDSGVPYLGICLGAQILARAL----GGSVTPH------------------------------------------------------------------------------------ +ENPSKILVVLHQQH-------STPGRIG-------RLLECQGYQLDLRRPRFGP----------------------------------L-PD--TMRDYAAAIIFGGPMSAND-DWLKREIDWIGVPLKENKPYLGICLGAQMLARHL----GQTVCPH------------------------------------------------------------------------------------ +ATPRSVLTITHQST-------SNPGNLG-------HLLRQQGFTLDLCCPALGP----------------------------------L-PQ--HLQSYAAVVILGGPMSANDQPFIRAELDWLPLVLESGKPFLGICLGAQLLARVL----GAKVAPH------------------------------------------------------------------------------------ +RDKRPILIILHQER-------SSPGRVG-------QLLANKGYNLDIRRPVLGK----------------------------------L-PT--TLENHAGSVVFGGPMSAND-EFIKSEINWLDIPLRENRPFLGICLGAQMLVRHL----GGKVQSN------------------------------------------------------------------------------------ +LTMLRIVAILHNPA-------GSTGYIG-------NILQAQQHEFRVLCPLAGP----------------------------------L-PE---ADSFDAAIVFGGKMSANDLPELLAELLWIRSVVESGKPFLGICLGAQLLAMAY----GGKITRH------------------------------------------------------------------------------------ +NNKLKIAVVLHRQS-------SQTGLLG-------QFLQRNGFSLDFYYPILGK----------------------------------L-PK--TLKHHAGVVILGGPMSVND-VYINEEIDWISLSLKDNKPFLGICLGAQMLAKNL----GGCVAAK------------------------------------------------------------------------------------ +DNKPKIAIVLHRPS-------GGMGYLG-------SFLQQSGFALDIYCPILGK----------------------------------L-PD--TLEHHAGVVILGGPMSVND-AYISEEIDWISLSLKENKPFLGICLGAQMLARNL----GGCVEAR------------------------------------------------------------------------------------ +ADERPILIVLHQES-------STPGRVG-------QLLEAHGVTLDIRRPVMGP----------------------------------L-PE--TLDGHGGAIVFGGPPSAND-AHLVREIDWLKVPLAEERPFLGICLGAQMLAKHL----GAPVASH------------------------------------------------------------------------------------ +DDERPVLVVLHQET-------STPGRVG-------QLLHAHGVRLDIRRPVIGR----------------------------------L-PE--TMDDHRGAIVFGGPPSAND-DYLKREIDWISVPLAEKSPLLGICLGAQMMAKQL----GGEVRPH------------------------------------------------------------------------------------ +-MTDQILIVLHQPT-------SSPGRIG-------QLLSRRGFTLDIRRPVLGP----------------------------------L-PD--TMAEHAGAVIFGGPMSAND-EFVRREIDWIGVTLREEAPFLGVCLGAQMLIKHL----GGEIRPH------------------------------------------------------------------------------------ +MTSNRILIILHQES-------STPGRVG-------QRLVQRGFELDIRRPPLGE----------------------------------L-PE--TLDDHAGAVMFGGPMSAND-EFVKRETDWLAVPLKENRPFFGICLGAQKLVRHL----GGNVTSH------------------------------------------------------------------------------------ +RHMKPILVILHQEN-------STPGRVG-------QVLRAHGVRLDIRRPVMGP----------------------------------L-PK--TLDAHAGAIVFGGPPSVND-DYITRETDWLSVPLNEDKPFLGICLGAQMLAKHL----GARVENH------------------------------------------------------------------------------------ +QRKLPVLVVLHQEN-------SSSGRVG-------QMLVEKGFPLDIRRPVLGP----------------------------------L-PE--TLAGHSGAVIFGGPMSAND-PYIRKETDWIGVPLKENKPFLGICLGAQMMVRHL----GGTVAAH------------------------------------------------------------------------------------ +GRKRPILAILRQEA-------STPGRAG-------KLLRDKGFELDIRRPVCGP----------------------------------L-PD--TLDGHAGVISFGGPMSAND-AHIRREIEWLSVPLAENRPYLGICLGAQMLAKNL----GCKVTAA------------------------------------------------------------------------------------ +EARLPVLIVLHQES-------STPGRVG-------NALRALGHRLDIRRPRFGP----------------------------------L-PK--TLEQHAGAVIFGGPMSAND-DYIRREIDWIEIPLREQRPFLGICLGAQMLAMQL----AARVAPH------------------------------------------------------------------------------------ +-MLKPVLIVLHQEQ-------STPGRIG-------HYLQVRGLPLDVRRPRFGR----------------------------------L-PE--TLDEHAGAVVFGGPMSAND-DYVRTEIEWLKVPLRERKPFLGICLGAQMLAKHL----GAAVGPR------------------------------------------------------------------------------------ +APHRPVLIILHQET-------SSPGRIG-------NALRARGYPLDIRRPRFGA----------------------------------L-PE--TLDAHAGAVIFGGPMSAND-DFVRREIDWIEVPLREQRPFLGICLGAQMLAIQL----GATVGPH------------------------------------------------------------------------------------ +THRPKVLIVLHQEH-------SSPGRVG-------QELVKRGFALDIRKPRFGS----------------------------------L-PD--TMRGHAGSVIFGGPMSAND-GFIHKEIDWIKVPLQEEAPFLGICLGAQMMVKQL----GGTVSGH------------------------------------------------------------------------------------ +QHPVKVLVVLHQET-------SNPGRVG-------QQLIKRGFELDIRRPRFGP----------------------------------M-PE--TLADHAGSIIFGGPMSAND-DFVKQEIDWISVPLKENKPFLGICLGAQMLSKNL----GGKVTGH------------------------------------------------------------------------------------ +AMTRRVLIVLHQER-------SNPGRVA-------QELRRRGCELDIRRPSLGP----------------------------------L-PA--TMAGHDAAVIFGGPMSAND-PFIKAETEWIGVPLKEGKPYLGICLGAQLMARHL----GARVYGR------------------------------------------------------------------------------------ +SNSLPVLIVLHQEA-------STPGRIG-------NVLRVLGHPMDIRRPRFGP----------------------------------L-PE--TLEHHAGAVMFGGPMSVND-DYIRREIDWLAVPLKEQKPFFGICLGAQMLAKHL----GARVAAH------------------------------------------------------------------------------------ +-MMARILVIQHSPY-------EPLGIII-------HTLKRMKLRIRYVNFARDH----------------------------------QRV---NMSRYHGIVVLGGAMHPNEYPHLIHEIELLQVALAKEVPILGICLGSQLLNIAL----GGFCYAL------------------------------------------------------------------------------------ +--MPRILVFQHVAA-------EPLGTLD-------PLIRRRGHRIRFTNFDRDD----------------------------------A-QP--NVDRYRGLIVLGGPMNVEDRPHLRTELLAIERMLEQGKPILGICLGAQLLAHVL----GAPVRRH------------------------------------------------------------------------------------ +--MPRILVFQHVAA-------EPLGTLD-------PLIRRRGHRIRFTNFERDE----------------------------------A-QP--NVDRYRGLIVLGGPMNVEDRPHLRTELLAIERMLEQGKPVLGICLGAQLLAHVL----GAPVRRH------------------------------------------------------------------------------------ +------------------------GTNAVDVVTIWSKLRDNGINVFFATPDGDPPNCNMFLSPWYLARMPVDSYDQMLNDINCMVPDSWDYPDFNLFDYDIAFIPGCTGAFQEMRSNCYLRAALRTFFPLPRILGAIGQGVLVINAAT----------------------------------------------------------------------------------------------- +-----------------------AGTEPVEAAVPIDVLRRAGADVTVASADDGELVVEVRIVAELVAGDCAVNL-----ELMGPPGNVPYIEEAHLEFCEICRAQGGVPGAANLGGCAALEAMVRRHAATGGLYAAICAAPPLALAS------WGMLNGLKVAKAS----------------------------------------------------------------------------- +-----------------------AGTEPIEASIPIDTPRRAGADVTVASAGD-ALLVEIKIMADLLA-DCAASY-----D--------------------LIVLPGGVPGAVNLGGSATLESIVRKHAEKGGLYAAICAAPPLALAS------WGLLNGHKVE-------------------------------------------------------------------------------- +--------------------------EELEAVTIIDILARAKIQVTTATINSNLTACSRGVK----------------------IMADKFLSEC-NEQYDVIAIPGGLPGADNLAGSQLLIQKIKEQLAANRFVAAICASPAIVLE------------------------------------------------------------------------------------------------- +---------------------------ETELFTILRKLAAADIDWDIVARRRVI-RAEKGNTDE---------FEV-DY----LL---REFDPKTLDQYCAVIFTSGETSTRHMWFSQEIKEIAERASEQEIPIGAVCCAAPCV---------RYIAKDRRVTGFPLHEILT-----------------LFKSAGAHITG------RSVEVDGTLVTAEA----------------------- +-----------------------------------------------------------------------------------------TISKVRNNIYDVLVIPGGMKGSNTISECSEFIDMLKEQKANNRLYAAICAAPETVLD------RHSLIDDVEAVAYPSFERNF-------------------KHIG----------KGRVCVSKNCITSVGPGSAVEFGLKIVE---------- +-----------------------NGAQLIDFAGPWEVFGTAGLLVHTVAEKAEPLTFGAKIIPD--------------YTF----EN--------SPRTHLLLIPGG-GVFQEAIKNPALIHWIQTKATEAKVVMSVCTGAFLLQAA-------GLLEGHTVTTTYG---------------------------------------------------------------------------- +------------------------------------------------------------------------------------------------NDFAGLVLIGGNS--WHKEESKAVMALVQKALDAHKVLGAICGATEFLG-M------NGVLNNIQHTGNR--LD-------------------ELQEAGENYTNAARYVEQQAVRDGNIITANGS---------------------- +---------------------------ELDFVGPYEVFSKVGQDVSVYTVDGKAVRCANGLK----------------------VEPDYSFAD--APQAHWLVIPGGQGRHREM-HNPAMLDFVRQAANHAEIVASVCTGAFILANAG------LLQKGRATTYHLALEE------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------------YADAVLFVSGPG-TRDCIKNEEWLSNFE-LDPERQAIGSICSGSLILAKL-------GLLEGKTATTYPTSKA-------------------LLEEMGVAVIE-----K-PFVENGNVATAGGCLAQQYL---------------- +-------------------------------------------------------------------------------------------------FADAVIFASGKG-VKDLYKNQQYINSIH-VDPQRQLIGSMCSGSLLLGAK-------KLLTGKKATTYPSAVE-------------------QLKEFGVDVIE-----K-SFVNEGNISTAASCFAAQEL---------------- +-----------------------------------------------------------------------------------------------------MLFGSGRL-TRQIARDEQLLSRIK-VAPERQLIGSQCSGALLLKKL-------GLVEGIPLCTDATTRP-------------------FLLETGAAVLD-----Q-SFYASGNIASAGGCLSAVYL---------------- +-------------------------------------------------------------------------------------------------NDDIIIFGSSSN-TDKIIDNNQIISELKKISPQNQIICSQCSGALFLEKL-------GLIHDASIATDIKTAK-------------------KLKLKGYNIAD-----K-PIWVDDNIISSGGCLSAIYL---------------- +-------------------------------------------------------------------------------------------------SADAVLFGSGMK-TREVASDEAIMSQIR-LEPSRQLLAAQCSGTFLLAKL-------GMLGRTPACTDLTSKP-------------------WVQAAGANIRN-----Q-PFIANGNIATAGGCLSAQYL---------------- +-------------------------------------------------------------------------------------------------QRHGDAVGSGIR-TRDVVSDPALMARLA-LDPSRQLIGAHCSGTLVSAKL-------GLLGSVPACTDLTTKP-------------------WVQETGVEVLN-----Q-PFYANGNVATAGGCFASPYL---------------- +--MKKILLFVY----P--------TFAEFEITVATAL-LKKKYEIITAGLTKEMIISET-------------GL---------QVQPHIELSEVRVEEYEGIIIPGGDE--IHMKEAKPLFQLFVNFLSKEN--------------------------------------------------------------------------------------------------------------- +--MKKALIFLF----D--------GFAEFEVNIASLFLISKQFEIITATVDGKTVTGEG-------------VF---------LCQPHVSMEHIEVADYELFIVPGGHI--FDHLENDQLLSIVNKLHEQNK--------------------------------------------------------------------------------------------------------------- +--MKKIAVILSGS-GVF------DGTEIHEAVLSLYAIELEGASWHCFAPNID----QHHVI-NHLTGEDMPETRNVLVE-AARIAQISDITTLNPAEYDALLLPGGFGVASDFAFHPDIKRVCQQFADEEKPAAYLCIAPTLI--------------------------------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------EPHRLSHVIAPPGLVVPSKMVSMAVPAQWMNTLYHEGVTLCSVCAGAFVLAET-------GLIDHRRATTHWAFAQALAE---RFP--------------AVDVAA-----ENMVIDDGDIITAGGILAWTDLGLTL------------ +----------------------------------------------------------------------------------------------DVNAPAFVISPPSVAMPGRMSAMPRQAQWLKELHSLGAIMCSVCAGAFVLAQT-------GLLARRRVTTHWAFAELLAS---TYS--------------DVQVTT-----ENVVIDDGDVITSGAILAWNDLGLLI------------ +----------------------------------------------------------------------------------------------EVNAPAFVVSPPSVAMPERMSAMPREAQWLKELHAGGAIMCSVCAGAFVLAQT-------GLLARRRVTTHWAFAGLLAS---AYP--------------DVQVTT-----ENVVIDDGDVITSGAILAWNDLGLLI------------ +----------------------------------------------------------------------------------------------DAHQPAFAIAPPSVVMPERMSDMPREAAWLAELHGRGVIVCSICAGAFVLAQT-------GLLARRRITTHWAFAELLSR---TCP--------------DAHVAS-----ENIVLDDGDVITAGAILAWNDLGFLI------------ +----------------------------------------------------------------------------------------------GHHDIDHLVVVPSEDPTTRLSLWDREIEFIRACEARGVRVSSVCVGAYLLGEA-------GLLDGRRCTTSWLYGADLAS---RYP--------------GATVRT-----DSLIVQDAGVTTTAAFTAALDLATAL------------ +----------------------------------------------------------------------------------------------QEKCFSALIIPPDLSGIPKISTDDRYIKFLRLHYKKGTILASVCTGAFLLANT-------GLLTNRHVTTHWKYGNILKN---FFP--------------EILLQI-----DKLLVDDKDIITTSGGMCWADMGLCL------------ +----------------------------------------------------------------------------------------------PDKEFTVIIIPPDLKGIPSISEDNLYIKFLQFHHQKGTILASVGTGAFLLAQT-------GLLENRVVTTHWKYGNIFKH---LFP--------------NIILQL-----DQLLIDDVDIVTSSGGVCWGDLGLCL------------ +----------------------------------------------------------------------------------------------DPSRFDYIVV--GGLMNEIERLHPDHIAFLRRAAEAGVSLVGVCTGAFILHRA-------GLMNGYKACVSWFHHEDFLT---EFD--------------GLLPVS-----DQIFVVDRDRLSCSGGASSAHLAAFL------------ +-----------------------------------------------------------------------------------------------LGKPDLLVVPGGGGGVRAVVEDGSLPDAVDERYTAGATVASVCTGAMILSEA-------GLLEGRPAATHPVAVDDLAG-------------------TDATVV------DERVVDDGDVLSAGGVTSGIDLA--------------- +--------------------------------------------------------------------------------------------------------------------SDQIASFIQKAHESSLVIGGICAGVLVLARA-------GILKGVKITHSTEKPESSVQLT-----R-PYW-------EGAIYQE------SLVQVDKRIVTAMPN---------------------- +-----------------------------------------------------------------------------------------------PDDVDILYLPGGYPEARQLSAATNVMNSIKDYIERGGYTLAECGGMMYLTSVLMTGTDTR--MEYNMAGVL----------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------SIAE--VKQLDILVIPGGLNETYMATKDTVLLNWIKAIDANSKYTASVCTGAWILAAT-------GLLKDQEATTHWF---------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------TITD--VKQLDVLLIPGGFKETYQLTKDETLLNWIRDIDSNSKYTASVCTGAWILGAT-------GLLEGKEATTHWY---------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------SINE--VKQLDILVIPGGLNETFTATKDTALLNWIKAIDVHSKYTTSVCTGAWILAST-------GLLKGHEATTHWF---------------------------------------------------------------------------- +----------------------------------------------------------------------------------------APLAHIDPVEFDALVVLGSSDTLCPLGYNESLWNSVQGFDAIKKTVAGIGTGALVLAHA-------GLLVGKRATCNPTPAV-----------------IADLKLHGALYSNE------SPVVAGWIVTATRG-GTHSFAEAVL----------- +-----------------------PGVELLDFAGPFEVFNTEGFHVTVASEPGKMF-----TSKGFV-------F-LPDYN----LN--------NAPEPDVLIVPGAPLTLTYLNNNVDLGNWIGQKNRTTKIVMSVCTGALLLSQL-------GLLDGKIVTTHASMLD------------------------------------------------------------------------- +----------------------------------------------------------------------------------------KSVEELKGKDYDAIIFPGGFGAAKNLSVHPQVERVVKEFHQLSKPLGFCCIAPVLAA---------RLISGVHVTVGSDQNR------------------------------------------------------------------------- +--------------------------------------------------------------------------------------------------------------------VELLVPLVEETVGEKKLVAGICNASVFLGVH-------GFLNGVKHTSNTLAYL---------KQY-----------AGDKYTGEADYVDKQAVRDGKIVTANGTGQ-LEFCREI------------ +--------------------------------------------------------------------------------------------------------------------AERVVPIIRQAVERGKIVGAICNGASFMAKC-------GFLNSVRHTGNGLEQL---------QTW-----------GSENYTNPAGYVNAQAVSDRRIVTANGSAT-LEFAREL------------ +-----------------------------------------------------------------------------------------------DRDADKVFVCAGGNP--ATFEDRGVFAWLRRLARKGVTVGGISGGPYILAKA-------GLLDQRRATLHWEHLPAF-------------------RETPITV-------MPSLEIDGTRITCSGGISALDMMVALIE---------- +-----------------------------------------------------------------------------------------------LLNMDIVFICGGFQL--YKNMTVRLKNFLYRLDQQKIALGGLCTGAYVLAKA-------NLLNGFRASLHWENTLAA-------------------QEEPVQF-------TPHITIDANRFTCSGGLA-------------------- +-----------------------------------------------------------------------------------------------LARADILAVAPLARG--ARDNGAEVAEALRDAARRNCRILAVGEAVLTLAAA-------GLLDGRAASTCPAHADEL-------------------RRRPVRI-------APGVYVDDPIFTAADGPAGLDLCLHLVR---------- +-----------------------------------------------------------------------------------------------LAGLDLLVICGGYRT--ELKASDNLIRLLREAAAQGVALAGLWNGAWFLGRA-------GVLDGYRCAIHPEHRPAL-------------------AEISGQV-------TSEAVADRDRLTASSPTGAYHMALEWIK---------- +-MCPRCTVVAP------------PTAGLPALAQR-RVHRRRAGDGEHRGSRAGPSAG------G--------------------------R--L-----VPLARIGRAGRTEGRPRSVALVASALARVAAGTRVVSICTASFLLAAT-------GLLDGRRATTHWFEAERLAR---MFP--------------RVTVDP-----DVLFVDDGDVLTSAGAASGIDLCLHLVRRDH------- +-SRHLVAVLAL------------EGVIPFELGIPARLFGMALYDVVTCTLTPGRLA--------NA-----------------------DFD-I-----VTVVIPASYH-VDDNGLPEPLAEALAS-LKPGTRLASICTASFILAAA-------GLLDGRRATTHWMHAEALAR---AFP--------------KVDVDA-----DVLFVDEGDVLTSAGVAAGVDLCLHMVRRDH------- +--RHQVVVLLL------------EPLIGYDATIPSAVLGAALYSVEMASLDGGPVQ--------TT-----------------------GYA-V-----VTVIVPGTRA-PGEGVLDDALERALSQ-IRPGTRIVSICTGAYVLAAA-------GLLDGRRATTHWQNTEDFAR---LFP--------------QVDLDE-----DVLFVDDGDVLTSAGLSAGVDLCLHLIRRDH------- +-AFHRVVAYAP------------PGTTALALGIVSSIFGPRGFDLAICARRAGPVQTD----L-G-------------------------LP-L-----TLIIVLPAVDYH--VEPSHPVLPVLRAAHDRGTTIAAHCVGTFTLAAA-------GLLGGRTVTTHWLFADELTT---RHP--------------EVTVRP-----EALYIDEGSIITGAGAAAGMDMCLHLIRREY------- +--MHTVAVLAL------------DGVIGLELTGACQIFATALYDVRVCGDPGGTSVLA----FDRP-----------------------VLR-A-----ETLVVPAAGEP------SPEVVELVRAAHRRGVRIASICTGAFTLAAA-------GVLDGRRATTHWDHTTELAR---RHP--------------AVEVVT-----DTLYLDEGDLLTSAGVTAGLDLCLHLVRRDH------- +-TRHRMVVVLL------------EDVLPLDYAIPIHVFGREAYDLVTVSVGGGPVPVA----GG--------------------------TT-V-----VTIVVPGYADAAG-RELPGSLLRALAGAHRRGVRMVSICSGAFALARA-------GVLDGLTVTTHWSLCADLAE---RFP--------------AVTVDQ-----SVLVAGTGSVLTSGGVTAGVDLCLHLLNADL------- +-RVRDVAVLAL------------PGALPMEIGMPFQVLQSRHYRLTLCGRSPGPVPTA----GG--------------------------FP-V-----VTVIVPAYDDIDQ--PPADDVLDALRTAHARGARVVAICVGAFALAAA-------GLLDGRRATTHWAYTHRLAA---RYP--------------LVRVDP-----DVLFVDEGDVLTSAGVASGIDACLHLLRTDL------- +-MLSNVAVLVW------------DEVALFELGVLCEAFGVDVLDFAVCGVEPGQVRTS----L-G-------------------------FG-M-----ELVCIPAMGMEG---PVPAPVIRALRDAVERGARVLSVCTGAFALGEA-------GLLDGREATTHWKHTDELAG---RFP--------------LARVVP-----EVLYVDAGPVITSAGSAAGLDAALHLWREAY------- +-GLKTVAALAL------------DGVITYDLACAVQMFRRGGFELVTCGEKPGTVWTP----D-G-------------------------FT-I-----EVVVVPGRAPHD--FPPSDEVLAALRDTHQRGAVVVSICIGAFVLAAA-------GLLDRRPATTHWEYCDDMRR---LYP--------------LVDLRP-----EALYVDDGDVLTSAGLCAGMDLCLHVVRREM------- +-RPHRVVALAL------------PGVVLLDLAAPAHLFGHCRYEFQLAGLAPGPVPDS----TG--------------------------VV-L-----CTVVVPGYGPLDN-PAPPE-AAEAVRAAYDRGARVMSVCTGAFLLAEA-------GLLDGRSATTHWAHTDELAR---LHP--------------KVTSVP-----DVLFVDEGRILTSAGVAAGLDLCLHVIRRDH------- +--MPVIALALS------------DGVPLFELAAPCTIFGTGWYEFRVCSPRRAKVD--------R------------------------WFT-A-----STVIVPACHDR--DHRPPVRLVEAVREAYDRGARVMSICTGAFVLAEA-------GLLDGRTATTHWMHAAKLAA---RFP--------------AVTVDP-----DVLYVDEGRVLTSAGKASGMDLCLHVVRRDH------- +--MHRVVVLAL------------PGVMSFELGMAARLFGAALYQVQTCSPDGEPVS--------DA-----------------------DFK-V-----ATVVMPPAHG-GASTELAPEVLAALSQ-IRPGTRLLGICTGAFFLAAA-------GLLKDRKATTHWRDTEKLQR---NFP--------------DLKVLP-----DVLYVDDGEVMTSAGAAAGIDLCLHVIRKDH------- +-RLRQVAVVIL------------DGAKPLDVGIPAQVFTTR-YEVRVCGVEPGLVS--------GD-----------------------GLS-Y-----SLIFIPGYRHPDR-DEPPAALVAALVAAHARGARIAAISTGAFALAAT-------GLLDGKRATTHWHYSRIFAE---QFP--------------QIQVNE-----SVLFVDEGAVLTSAGAASGIDLCLHILRGDL------- +--MSVIAILAL------------DGVLPFELSIPGQVFGTAHYQLRVCAPNPTV-TTS----PEHG-----------------------AFQ-I-----QTVIVPAHAGFL--DPPPNLVVTALRDAAARGARMASMCVGAFTLAAT-------GLLDGHKATTHWQYADELTR---RHP--------------RVAVDS-----GVLFVDNGDLITSAGVAAALDLCLHLVHRDL------- +-RPHRVGVIAL------------PGVYPYELGIASRFFGAAAYEVVTCSLDGAPVATA----AD--------------------------FS-V-----ATVVVPPWETST-GDP--------VGLAALGVPRVVSYCTGAFTVAAS-------GLLDGRAATTHWCAADEFRA---AFP--------------QVDFRP-----DELFVDEGDVLTAAGASAAIDLTLHIIARDL------- +-AMHRIAVVAL------------PGVFPYELGVPARFFRAALYSVTTCSLDGAPVQTN----AD--------------------------FS-V-----ATIIVPPWSAAE-GDP--------IGLADFADRRIVSFCTGAFTVAAS-------GLLDGLEATTHWCAAEEFAR---RFP--------------QVRLRT-----DELFVDSGRILTAAGASAAVDATMHLIASDH------- +-LPGLVAILAY------------DGLCTFEFGVAVEIFGLEWYEHRIVAVDDGPMRAM----G-G-------------------------FQ-V-----LTIVVPGWRSRS--EPPSEALLDALRRAHARGARLLSICSGAFVLAAA-------GLLDGLGATTHWRYTDELAK---SFP--------------AVRVDP-----DVLYVDSGQVITSAGSAAGIDACLHLVARDY------- +-AVLTVAVVVC------------ENFSPFHLSIPSMVFSD-QFELFFCAEKPGTVA--------EH-----------------------GFS-I-----NLIVVPYWNHP--DTCPSTRLLDALRVAEARKAQIAGLCLGTYVLAYA-------GLLDGRRASTHWAFEQDFIA---RFL--------------DVRLDT-----NALYVEDEHLITSAGTVAAIDCCLYLVRQHC------- +-------------------------MNLLDLSGPVQVFTTAGYRVTYVSPRPTV-R--------AQ-----------------------GLE-L-----ALVLVPGPDLSRS-LEISPAVVDWIQGAARAGATIASVCTGAFLLGEA-------GLLDGRRCTAHWSVIREMRR---RYP--------------RARVAD-----DLLYIMDEPIFTSAGIASGIDLALAIVERDH------- +--MHKVAVVVQ------------DGAEPFGLGAMCEVWAEPVFDFVVTTPRPGRVRGS------V-------------------------FD-L-----HLVCVIPKRGYL---DPSPEVVELVQHAHDRGAFVFAHCTAAFVLGEA-------GLLDGKRCTTHWRHVDELAA---RHP--------------LAQVDG-----NVLYVQEGTVVTGAGSAAGLDAALHLMRQQF------- +-MLNSVAVLVL------------DGVAPFELGVLAEVFGTDGYRFDVCSPQ-ATVRTS----A-G-------------------------FQ-L-----VLVAVPAHHG-D--TAAHPEVHAALRRAADRGAYLFSVCSGAYLLGEA-------GLLDGRECTTHWRHVDELQR---RHP--------------EARVRC-----NSLYVQDGRLLTSAGTAAGIDACLHLVRQEH------- +--MRKVAVVVQ------------DGAEPFGLGAMCEVWAEPVFDFVVVTPRPGRVAGA----S-G-------------------------YD-L-----HLICVAPKRDFL---DPSPEVADLLARAHARGAFVFAHCTGAFVLGEA-------GLLDGRRCTTHWRHVDEFTR---AFP--------------EAKVDP-----DVLYVQDGTIVTGAGSAAGLDAALHLMRQQF------- +--MRTVGCLVF------------DGVRPFDYAVIGEVWAERDFELRVCGPDGARVRLG----G-G-------------------------LE-R-----VLVVVPGVERPD--EPRDPAVHAALRAAHGRGVTIASLCAGAFVLAEA-------GLLDGRTATTHWALADRLAE---RFP--------------AVDVRP-----EVLFTGEGRLWTSAGVAAGIDLCLHLVRAAH------- +--MHVVAVLLL------------EPLIGFDATIAPMCFGKALYEVVTCSVDGGPVMTT----NG--------------------------YA-I-----ATVIVPGNRQPQIEGVLPETVRD-ALSLIRPGTRLVSICTGAFTLAAA-------GALDGRRVTTHWQAGGDLAR---LHP--------------AVDLVE-----HVLFVDDGDVLTSAGVASGLDLCLYIIRGDH------- +-SRHRIAVVAL------------DGVKALDLAIPMDVFTVDPYDLKICGLTD-RVMTA----SG--------------------------LA-L-----ATVIVPGYHPVD--RPVPAAVVDALVRSLARGARMASICTGAFALATA-------GLLDGRRATTHWQHLDELQA---RFP--------------SVTIDR-----DVLYVDGGNLLTSAGMCCGIDMCLHIIMRDL------- +-QPHRVVVLLL------------APVIGFDATIPPMTFGAALYDVRLCSIDGQPVAST----HG--------------------------YT-I-----GTVIVPGTRHHTVDGELPADVVT-ALERRSPETRFASICTGAFALAAA-------GVFDGRPATTHWQAAREFAA---MFP--------------AVAVDE-----KVLFVDDGDVLSSAGLSAGIDLCLHMIRRDH------- +-SLINVAIVAV------------DGFSPFHYSVPCILFGD-RFNVTICAETPGFLT--------KD-----------------------GFA-L-----NIVVVPYWQHV--LERPPQTLLDSLVQARDNGAEIVGLCLGSFVLAWA-------GLLDGKRAATHWEFEHQFQS---LFP--------------YVQLDI-----NALYVDDGNIITSAGTAAALDCCLYIIRQRF------- +-RQHQVAVLAL------------DDVVAFDLGMPAQVFHAAFYRVQTCTLGGRPVR--------AA-----------------------GFT-V-----TTVLVAGVYYGAESGAIDQEIVDALRSAHARGARIMSICTGAFVLAAA-------GLLDGMRATTHWAHAETFRS---LFP--------------AVELDP-----DVLFVHDEPISTSAGVGAGIDLCLQVVRDDH------- +-MLSNVAVPLL------------DTVHPFELGVLCEVFGLDVYDFAVVSAEGPTLSTH----A-G-------------------------FT-I-----TLIAVPTGGSYPT-G-YPEELLAALRRAVDRGARVLSVCSGAFVLGAA-------GLLDDRRCTTHWRYSAALAR---RFP--------------RAVIDP-----DVLYVDAGPVVTSAGTAAAIDACLHILRQEH------- +-MLKSVAVVLI------------DGFAPFEFGVLCEVFGIDPIEFRVCGEVAQALPSS----I-G-------------------------VR-M-----ILVALPACTI-R--DDYPPAVLDAIRAAHARGATVLSVCSGAFLLGAT-------GLLDGRACTTHWRHARDLAD---RFP--------------AAKIDP-----DVLFVDDGDIITSAGTAAGIDACLHLVRREL------- +-ALSTIAALIT------------DPVAMFETAIACEVFGLDPFTFMMCGETALPVPTT----S-G-------------------------GA-L-----TLVVMPAGGV-R--DTYPEELLDVIRGAHARGATILSICTGAFILGET-------GLLDGLTAVTHWRYAESFAK---RFP--------------KTTVSM-----DVLYLDHGQIVTGAGTAAGIDAVLHLVRREL------- +-ALRRVAALVL------------DGLAIFEFGVICEVFGVDPVDFTVCGPRAQPVRTS----F-G-------------------------AT-L-----TLVAIPAIR--Q--DDYLPEALDAVRAAADAGAIILTVCSGAFLAGAA-------GLLDGRPCTTHWGLTEELAR---RYP--------------TARVDR-----NVLYVDDGDLITSAGTAAGIDACLHLVRREL------- +--THRVAVLAL------------DGVLPLDLGIPARVFNEALYSVGTCSLGGRPVR--------HE-----------------------DFR-I-----VTVVIATQEPTPDTGTLPEDVTAVLKG-IRPGTRIVSLCTSAFLLAAA-------GLLDGMRATTHWTLCEAFTH---LFP--------------GIEVDP-----NVLFVDNGRILTSAGGAAGIDLCLHLVRLDH------- +--VHHVVVLAL------------DGVKPFDLGIPSQVLGQALYRVSTCSIGGRPVV--------NQ-----------------------DFS-I-----STVVVATQDHRRGRGDLPDRLAAALRS-VPSTARVVSLCTSAFVLGAA-------GMLDGQRATTHWQMCDELAR---RFP--------------RVTVDQ-----NVLFVDNGRILTAAGAAAGLDLFLHLVRRDH------- +------MVVVQ------------PAVNLLDLAGPVQVFDAAAYRLEYAAVADRV-D--------AQ-----------------------GLR-L-----ALVLVPGPRLERTGVRVDPELVTWLRRSAAAGAEFAAVCSGAAALGEA-------GLLDGRRCTTHWELLEPMRS---RYP--------------RAKVQD-----GVLFTHDGPVSTSAGVASGIDLALSLVHRDH------- +-MLTKVVVPLL------------PLTEAFELGVACEVFGFDVYDFSLIAAVPDPIRTR----F-G-------------------------YS-I-----DLIIMSAGGTATADGHDLEPLAEKLRAAVARGARVASLCTGAFVLGEA-------GLLDGRRCTTHWRHAARLAE---RFP--------------GATVDS-----NVLYVQDGNVYTSAGTAAGIDLCLHIVRSTQ------- +-SALSIAVIAT------------REFSPFHLSVPSMVFDK-LFNVEICALEPGVVV--------DI-----------------------GIS-I-----NIVIVPFWSHP--DERPAQTLLTALARAWARGAEVVGLCLGAYVLAYS-------GLLDNRRASTHWEVEHDFAA---RFP--------------TVKLDR-----NALYTRDERLITSAGTAAGIDCCLNIVRERC------- +-SALRVVVIAT------------HGFSPFHFSVPSMVFDK-LFRVDICAEQPGRVE--------DI-----------------------GMS-L-----NIIIVPFWEHP--ATEPSPELLAALRTAWQRGAEVAGLCLGAYVLAYA-------GLLNNRRASTHWEYERDFAG---RFP--------------HIRLDS-----NALYTRDERLITSAGTAAGIDCCLHIVREKY------- +-NRHHVAVLVR------------DGVLPLELGLVHQLFGVALYSVRTCAL-EGPVR--------DA-----------------------DFV-V-----RTVVIPASHELDE--VLSPALADALGRI-RPGTRLASICTGAFVLAAA-------GVLDGLRATTHWKSVERFRS---TFP--------------AVHLDP-----DVLYTDNGDVLTSAGEAAGIDLCLHLIRRDH------- +-AAHDVVVLVR------------PGVLSMELGLIHQIFGRAGYRVRTCALRPGRIATD----AD--------------------------FA-V-----GTVVVPASYAADEPGVLDG-GLREALTGLPSSTRIASICTAAFVLAEA-------GLLDRQRATTHWMAFDHFRR---RFP--------------DVVLDP-----DALFTDNGRVLTSGGDACGIDMCLHLVRRDL------- +-APHRVSVLAV------------EGVIAFEVAIPERILGTTLYDVRVASLDGGPVRTS----SG--------------------------YR-L-----LTLVVPAVALGGPPREPDPAVLE-LIRSAAARGRVVAICTGAFVLAAA-------GVLDGRRATTHWAHADRFRY---RYP--------------QVELEP-----DVLFVDEGNVLTSAGVAAGIDLCLHLVRRDH------- +--MRTIGVLLL------------PGSRMFDLAVIAEVWAQDPFTVRVCAPGRGRTAVS----P-F-------------------------GE-V-----VLVLAPGRVDPL--AEVPDAASAALRRAHRSGAVVAGLCSGAFTLAAA-------GLLDGRPATTHWRDLDALAI---AAP--------------AAELRR-----DVLYTEQDGVLTSAGVVGGLDLCLHLVRRDH------- +-AMRTVGVLLL------------PGSRAFDLGVIGEVWGVDPFEVRLCASGRGRVAIH----P-F-------------------------GQ-V-----ELVLVPGRVDPH--AEVPVAAVAALRKAHRAGITVASLCSGAFTLAAA-------GLLDGRSVTTHWRLLDDLET---AAR--------------DAVVQR-----DVLFTDEGDVLTSAGVVGGLDLCLHLVRRDH------- +-DMDTVAFALT------------DGMLHFELSVAQEVFGSAWYDMSVCGPGPVRVG--------R------------------------F-L-L-----ETVIVPGWADI--DVDPPADLVDAVRAAHEAGSRVASLCTGAFVLAAA-------GLLDGLRATTHWAHTDALAA---RHP--------------LVEVDP-----DVLYVDNGTVLTSAGKAAALDLCLHLVRLDR------- +--MLKVACIVD------------DDVSAFELAVAGEVFGYDRHDFRVVTQTPGPVRVA----G-GL-----------------------DLP-M-----MLLILTPYAQCE-DGECSLAVSRVLQRAVERGARVLALCSGAFVAAKA-------GILDGRRATTHWRHIDGLAA---QFP--------------HIALER-----DALWVDDGPVTTSAGTAAAIDASLHVVRQLH------- +-PLHHVAVLVL------------EGAKPLDVGIPAQVFTTR-YEVRMCGAAPGLVT--------GD-----------------------GLA-Y-----SIVFVPGYRHPDR-DDPPLAVVEALVAAHARGARLAAISTGAFALAAT-------GLLDGKRATTHWHYTQALAA---KRP--------------LVRVDE-----NVLFVDEGSVLTSAGAASGIDLCLHILRGDL------- +--MHQVAVLAT------------DGVMPFELSTPSKIFGNALYRVTTCTMSGGPVM--------AA-----------------------DFS-V-----TTVVIPPAEEMTRRDLLPADLANALGQ-VRPDARLVSLCLASYVLAAG-------GLLDGLRATTHWRHAEHLQR---CYP--------------AIAVDP-----GVLFVDTGRILTSAGAAAAVDLCLHIVRRDH------- +-PNKRVVALAY------------DGLCLFEFGICCELFGLKWYSFEVASLDPQPLRAS----N-G-------------------------VR-V-----ETILIPGWSGIN--DPIPGRLRDALCQAHANGARLLSICSGVFVLAAT-------GLLEGKQVTTHWRYSEALSA---RYP--------------DLVTVP-----NVLYTDNGQILTSAGSAAGIDLCLHLIRRDF------- +--MHRVAVLVF------------DGVHSFDLSMPIQVFTTALYDVRVCGEGRDLSIGV----GGHE-----------------------MYR-C-----TTIVVVGVTSD---REPPAEVIDLLQEAHRRGVRIASISSGARVMAEA-------GLLDGRRTATHWSRAHVLAE---RYP--------------QITVDT-----DVLYIDHGDVLSSAGAASGIDLCLHMIRQDF------- +-NKHRVMVLAV------------DGVLPMDLGIPTQIFNARPYELTVCGDTEETVTTS----AG--------------------------FT-L-----GTIIVPGFEDFRRR----PRVRAALKLAGRAGIRIASICTGAFAVASA-------GLLDGRTVTTHWASADDLEE---LYP--------------RLRVDR-----NVLYIDNDTILTSAGFTAGIDLCLHLVRKDL------- +-APHQVVVLAL------------APVVAFDLSIPAQMLAMVAYDVRTATPDGSAVATV----NG--------------------------YG-V-----TTVIVAGTRCPDVDGVLDARIAE-ALRAARRRARMVSLCTGAFVLAAA-------GLLEGHRAATHWRYADQFRR---LFP--------------AVDLDI-----DPLYVADRGVLTSAGGAAAIDLCLHLIREDH------- +--AHRVLVLGV------------SEVVGFDLTIPSQILSKALYDVRVGSLDGGPIR--------SS-----------------------GYS-V-----LTLIVPGTYV-AGDGTLPADLAGYFAA-LPESTRVMSICTGAYVLAAA-------GLLAGRPATTHWAHVEHFRT---LYP--------------AVDLHP-----DVLFVDDGDVLTSAGVAAGIDLCLHVIRRDH------- +--MRSVAVVIQ------------PGFAPFEFGLACEAFGLDNFDFRIVAPEPGVVPSN----I-G-------------------------FS-V-----NILVLAPIPRDQ-WGTVDPRVVEVVRAAHARGAWLLSVCSGSFVIAAA-------GVLDGKRATTHWRYADVMAR---MYP--------------EIEVDP-----DVLYVQSGNIVTSAGTAAGLDACLHLLRQEL------- +-RPHRIAILVL------------PGANPLDVGIIAQLFSPRPYELRHCSLEAGPVTGR----DG--------------------------LG-F-----VTVIVPAWATPTTAAPPDPRALDALREAAGRGARTVSICTAAFVLAAA-------GLLDGRRATTHWSRTELLAR---TYP--------------EISVVE-----DVLFVDEGQILTSAGQAAGIDLCLHLIRRDH------- +-SPHRVVFIAV------------PPVMTHDLSVAQAVLEDVAYRVDVATPTPGLVATV----TG--------------------------PA-L-----ATVFVIGGGPQP-VGER---LRALLRTAAESGRRVVGACTGVFVLAEA-------GLLDGRRATTHWHVLDRLAR---DFP--------------QIEVER-----EALYVDDGSVLTSAGAAAIVELCLHLIRTDH------- +-HPGTLAVAVS------------PGMPIFEMAIPYQIFYQPWYDFRLCGPRGARHA-T-----LRD-----------------------PFV-A-----LTVIVPSTPNV--REDPPADLVDAVRAAYERGARIASLCSGAFVLAAA-------GLLDGRRATTHWRHLAALRE---RCP--------------SLDIDP-----GVLYIDDGRILTSAGTTAGLDLCIHLIRKDL------- +-VPGTLAVLLL------------PQQAAIEVALACQAFGTPWYDLRLCGVDGAGAHVGLRHAGPAG-----------------------SFG-M-----CTVLVPGTGDV--HTDPPAAALAAIRAARARGARMVSLCSGAFVLAAA-------GVLDGRTATSHWEHAALLAS---RFP--------------AVRVDP-----NILYTDEPDVLTSAGLMAGIDLCLHVIRADL------- +--VHDVAVLAL------------PGSIAFELGLPHRLLESALYRVRVATLDGGPVR--------SA-----------------------GYS-I-----TTVVVPGVHG-GPDGTIPDGLADALRT-AAGHARLVSICTGAFVLAAA-------GLLERRPATTHWMHAETLQR---LFP--------------AVRVDP-----GVLFVDDGDVLTSAGNAAGIDLLLHLVRRDH------- +-STIHVAVLAF------------QGVSLFQLSVPAVAFGVVDYAVRICAHIPGRIT--------DQ-----------------------GIV-I-----DIIVVPAWETP--EAEVPADIISELQEANRRGALIIGFCLGAFVLAAA-------GLLDGRAATTHWIARELFAR---RFP--------------KVEFRP-----DVLYVTDGNIVTSAGTVAAFDCCLEIIRIQH------- +--VHRVAVLLI------------PPVIAFDATIAPMLFGYALYEVVTCGVDGEPVH--------TN-----------------------GFA-I-----VTVVVPGTTY-AADGVLEEDVSAALAR-IPAGTRLVSICTGAFVLAAA-------GLLDGRPATTHWRWADELRR---LHP--------------KIAVDE-----NVLFVDDGDLLTSAGLAAGIDLCLHIIRTDH------- +-QPHQVAVLAL------------DGVYPFELGTPTRILGAARYEVAVTSVDGDPVR--------EG-----------------------GFT-I-----TTVIVAPIDP-A-TRDLPSGVAAALAR-ITPGTRIASICTGGFILAAA-------GLLDHRPATTHWECAPLFRK---WYP--------------HIRLDE-----SVLFVDDGDVLTSAGAASGIDLCLHLIRTDH------- +--THVVAVLAL------------SKVIGYDLTIPTMVFDATPYDVRICGVDNKPVD--------YG-----------------------GYR-M-----LTVIIPGTQI-TGEGTLPGEVADALAL-IRPGTRVMSICTGAFVLAAA-------GLLDGRPATTHWKHTEKFRE---LYP--------------KVQLNE-----DVLFVDDGDILTSAGLAAGIDLCLHVLRNDH------- +-AMHTVAVLAL------------EGVVPFDLAVPVDTFGRAAYRVKICAGRSISGTVE----ADGG-----------------------AFS-L-----RTIVVPGVGEQA--GPLPPESVTALRAAAARGTRIASICVGAFLLAQT-------GLLDGLRATTHWIAAEELAR---RHP--------------AVRVDP-----NVLFVDNGQILTSAGAAAGLDLCLHMIRSDH------- +-------MLGL------------DGAIGFELMTPGQVFGMARYEVRLCASGRSI-STA----ADWG-----------------------ATE-L-----RIVIVPGTERFL--DPPDSAVVQVLRDAAARGSRVASICVGAFTLAAA-------GLLDGLRATTHWQWADDLAR---KYP--------------AVDVDP-----AVLFVDNGQTLTSAGVASGLDVCLHLIRTEA------- +-TTIRVAVLAF------------EGVSLFHLSVPGIVLGAVRYEINYCAQVPGMVR--------DH-----------------------GLG-I-----AVIIIPAWGDD--LGPASASLIKALQDANAQGKLIVGLCLGSFVLGDA-------GLLDGKEATTHWIARDVFAQ---RFP--------------AARFRP-----DVLYVSADNIMTSAGTMAAIDCCLHLIRERH------- +-PTHRVVVLAL------------EGAVAFELGLPHRFFATSPYDVAMCTVDDGPITTS----AG--------------------------YQ-V-----LTVVLVGMPWHEVNGKLDAPIRE-ALALVPDSARWLSICTGAFVLAAL-------GKLDHGQATTHWIHADAFRR---LFP--------------HIDLDP-----EVLFIDNGDVLTSAGNAAGIDLLLHVIRRDL------- +-PMQRVAIVAQ------------PGIRSFDLAVITEVWGPDVFELRRCALDEGPITLP----G-G-------------------------LT-L-----MLIVVPALAEPA--DPTPEPVLAALRTAHARGVPVAALCAGAFVLAEA-------GLLDGRRAVTHWWLAPQLAA---RYP--------------AVLVEE-----APLFVEDSGLWTSAGVASGIDLCLHLVREAH------- +-ATRTVALIVD------------EHSNPFEVGCATEIFGISPYTLTVVTPRPVRMR--------DG-----------------------LFQ-V-----SLVIVPNRPAVE--LTSRPAVLRTIRRAHERGAHLIGLCTGAFTLAEA-------GVLDGRRATVHWQLAAEFRR---RFP--------------AVHLEP-----DVLFVDDGDVLTSAGSAAALDLGLHVVRRDF------- +-TRHAVVALAV------------PATVAMDLAIPAQVFGHLHYTFTLCTEQPGSLPTT----TG--------------------------FA-L-----ETVVVPGYAPLVT-PAPGV--LDALRAAADRGVRLMSVCTGAFALAAA-------GLLDGQRATTHWEDAGDLAA---RHP--------------TVQVDP-----NVLYVDGERILTSAGVCAGIDLCLHILRRDL------- +-NPHRVVVLLT------------EGLVLMDMAAPVQLFGHVRYALSTCTEYPGPVPTC----AG--------------------------VS-V-----HTIVIPGYHDAAR-RTPSRTVTAALRQAHRRGARIASICVGAFTLAES-------GLLDGRRATTHWLDAAALAA---RYP--------------AVEVDP-----SVLYVDDGDVLTSAGLAAGIDLCLHLVERDY------- +--MHHVVALAL------------PGVVAFDLAIPAQVFGASLYRFSLCASEAGPVTTS----TG--------------------------FD-L-----ITIIVPGYEPHDP-PVPPV--AEALRAAAARGARLVSVCTGAFALAAS-------GLLDGRRATTHWLDAPDLSR---RYP--------------AVEVDP-----APLYIDATPILTSAGFSAGIDLCLHLVREDL------- +-SAHRVVAIVD------------DGSNPFEVGVATELFGLRWYELRLCSATPVSMH--------AG-----------------------FFT-I-----STVLVPNRPDPE--VPPSGPVLDAVRTAASRGARLMSFCTGAFTLAEA-------GVLDGRRATTHWRWADVFRS---RFP--------------RVDLDP-----DVLYIDEGSVLTAAGSAAALDLGLHIIRNDH------- +-NRHVVGVLVD------------EGSNPFELACLTEVLGIDLYDLRLCARRPVGMR--------QG-----------------------FFS-M-----TTVVVPNRPDTA--RPHRPDVLEAIGRAHARGARLIGMCTGAFTLAEA-------GVADGRRVTVHWQWADEFRG---RYP--------------RVRVDD-----EVLFVDDGDILTSAGSAAALDLGLHLVRRDH------- +-PIPSVAVVAC------------DQFSPFHLSVPCMIFGD-LFRLRLCAGEEGVLR--------AQ-----------------------GLQ-I-----DIVVVPYWRNP--QETPNPALLEALAEAYARGSLLVGLCLGTYVLAWA-------GLLTQRSAATHWEFAQDFQQ---RFS--------------DVRLDT-----QALYVEDERLITSAGTAAGLDCCLHVVRKYH------- +-APISVVVVAP------------AGISPFHLSVPMMIFDL-LFTLRIAAEDTRVAL--------GG-----------------------QVG-V-----TVLIVPGWADL--DRAPSAALRAALVAATQRGAHVVGLCYGAYALAYA-------GLLDGKLASTHWHAEADFHH---RFP--------------RVRLDM-----NALYVDEQRIVTSAGTGAALDCCMYLVRKLC------- +-EFLETANVIH------------QYLL---RSQKSSSSKEEPFEFETASLTGKSIQ--------TG-----------------------GLI-L-----TLIIVPGFMFNILELPQLAPISQWLKEQHEQGAYIANICTGAFVSAQA-------GLLDNKRATTHWLFCEQLQT---HFP--------------KVKVHT-----ERTVTDDGLIMCSGGSTSSADLLLYIIRKFG------- +-DPHRVVVLVD------------ENSNPFELGCASEIFGLRLYDFRLCSPEPTRMR--------DG-----------------------FFT-L-----TTLIVPNRPDVD--VPRRPAVLEAVRRAHARGARLLGLCSGAFTLAEA-------GVLDGRRATAHWQWADSFRA---RFP--------------SVRLEP-----DVLFVDDGDILTAAGSAAALDLGLYVVRLDH------- +--MISVAVLVA------------DGTLNFELAVPGQVFGSALYDVRVCAPTGVAEAPDHWHTAASH-----------------------GGP-P-----VLVVIPGGDADGVHHTADPATIDLLTHAYENGARLASLCVGAFTLAST-------GLLDGRKATTHWAYMDRFAE---LFP--------------LVELQG-----NSLYVDDGQILSSAGVTASIDLCLHILRSDY------- +--PHRVAVLAL------------DGVTPFDLGIAERVFPAALYEVATCSLGARPVS--------ST-----------------------GYD-I-----RTLVIPTPTG-SSDGTLPPALLRELTR-AAPDTRLVTICTGSFVLAAA-------GLLDGRPATTHWAYTQRFGA---LFP--------------RVELLP-----DVLYVDDGDILTSAGGAAGLDLCLHIVRKDH------- +-RPHRVVVLAL------------DGVYPFELGIPNRVFGTARYEVVTCSLDGRPVR--------NS-----------------------DFD-I-----ATVVIPPCDV-LPKDGLPQAVSEALAS-IPPGVRLVSICTGAIVVAAA-------GLLDDRPATTHWNFAERFGR---VYP--------------RVKVDP-----NVLYGDDGDILTSAGATAGVDLCLHLIRSDH------- +-PVHRVAVLAL------------AGMAPLDLAIPLQIFAPRPYEIRVCGPGG-PVPTA----NG--------------------------FA-M-----ATLIVPGFAPGP-PTPFPREVLDALVMAHARGRRVVSICTGAFVLAEA-------GLLDGLHATTHWQYTDRLER---EYP--------------TVHVDR-----DVLYVDEGSVLTSAGMCCGIDLCLHIVRGDL------- +-PPHRVAVIAV------------PPVTMFDLSIPQLVLGATGYEVVVCAADPGPVAVEGD-GGG--------------------------MG-L-----TTVIVTGTGARV-ADAR---VLAALRAAAAAGRRIASICTGAFVLAQA-------GLLDGRQATTYWVQAGALSS---RFP--------------AVDVRA-----DVLFVEDGQIVTSAGLAAGIDLCLHLVRSDY------- +-AVIKVGVVVF------------HDIIPFHLSVPCAVFEHAAYQLMVCATEPGPLR--------NA-----------------------GFS-I-----IMVIIPSWNDP--ALMPSAELVAALHRAHARGARLVGLCMGAFVLAAS-------GLLDGRPATTHWNWMSAFLQ---RYP--------------SISVDH-----NVLYIDDGDIITSAGTAASIDCCLHLVRQQC------- +-DPAKVAVVVQ------------PGYVLLDVAVPQQVFGRWPYELTLVSAVPAE---S-----S--------------------------LV-P-----RTVIVAGVQDPT--ESPDAELVERLRDAYDRGSRMVSICTGAFALAAA-------GILDGRSATTHWNWARLLRD---RHP--------------SVKVRE-----AELYVEDSGVFTSAGVLAGTDLCLHLLRLDH------- +-AMHRIVVVAV------------PPVTTLDLSIPAAVFPAAAYEVVICTAEPGIVPGY----TG--------------------------PS-V-----VTVIVTGTGARA-ADQR---VLDALQRAADDGRRIASICTGAFVLAQA-------GLLNGRPATTYWQYSQEMRR---RFP--------------AVDLRP-----DVLYVDDGTVLTSAGLAAGLDLCIHMIRRDH------- +-SSPLIVIMAY------------DQLCTFEFGCAFEVFGLSWYRCLTVAAE-EPIRAA----G-G-------------------------LR-L-----ETIIIPGWRGPD--AVAPPLLLDALRRAHAAGTRIVSICGATFVLAQA-------GLLAGKRATTHWRHASILAS---RYP--------------DIVVEG-----DALYVDEGDILTSAGSAAGLDLCLHIVRKDF------- +-APTIVAVIAY------------DGISPFHLSVPSVVFGKEAFEFRVCSSERGPLATT----G-G-------------------------FT-I-----TIVIVPSWRDPD--ETPPDELLDAVRAASARGAQLVGLCLGAYVLAAA-------GLLDGRPATTHWAWADDFAQ---RFP--------------RVKLDP-----DVLYVDDGNLTTSAGTAAGLDCCLHVVRRRF------- +-PTVKIAIVAF------------NYISPFQLSVPCLVFGENHFAVKVCAAEEGELQ--------NA-----------------------GFS-I-----QIVIVPSWRDA--NEIPAEELLSAIRDAFSSGAIIVGLCLGAFVLAAA-------GLLSGRPATTHWLLTDELAK---RYP--------------DIDVRP-----DVLYVDDGQIITSAGVAAGIDCCLHLLRRLH------- +-GRHRIVTLVR------------DGVIPLEVGIPHRLFGQALYEVLTAAL-QGPVR--------EA-----------------------DFC-L-----DTVIVPAAPEDYDQGRISDELRQALATI-RPGARVASICTGAFVLAAA-------GILDGHRATTHWKNAPDFER---RFP--------------QVDLDP-----TVLFTDCHNVLTSAGVASGLDLCIHMIRSDH------- +-GRHRVAVFIR------------NGVLSFELGIVHRIFGQALYELSTCAP-EGVVS--------DA-----------------------DFD-I-----ATVVVPGSQLDFE--FADSSTVLALSNI-RSDARIASICSGSFLLAAA-------GLLDGRRATTHWRSSKRFRA---LFP--------------QVEFHP-----DVLYTDDDGVLTSAGAAAGIDLCLHIVRTDH------- +-PRHRVAVLVR------------HGVLPMELGLVHQLFGAALYEVVTCAP-EGTIR--------DV-----------------------DFT-L-----HTVLVPASHELDEPGSLDRELTEVLTEA-AGRGRLASICTGSFVLAAA-------GLLDGRRATTHWQSTDRFAR---AFP--------------YVTVDP-----DVLYVDEGAVLTSAGEAAGIDLCLHMIRGDH------- +-MAHRVVVLAR------------PGVLPLELGLIHSLFNAARYEVITCGL-AGQVR--------KA-----------------------DFA-L-----MTVVIPAAYDPHDTAPLTGRLATAMSMI-RPGARIASVCTGAFVLAAA-------GLLDGRPATTHWEDADAFRR---TFP--------------EVHLDA-----DVLYTDDGDVLTSAGGAAGIDLCLHLIRRDF------- +-GKHTVVVLAL------------DGVVAFDLGIASRVLNSAAYEVLTCTADGGPVR--------TA-----------------------GFA-L-----LTVIVPGPCE-GPSATLPGDLVAALAR-VPAKARWVSICTGAFVLAAA-------GLLDGRPATTHWMHTETFRA---LHP--------------RVQLNP-----DVLFVDDGDVLTSAGAAAGIDLCLHIVRRDH------- +-GRHRVAVLAR------------AVLLPIELGIVHQLFGQALYEVATCSP-AGDVR--------DG-----------------------DFT-V-----ATVIVLSSYEDYVTPALPAPLAEALALI-RPGVRVASICTGAFVLASA-------GLLDGHTATTHWRYTELFAR---LFP--------------HVGLDP-----DVLYTDGGSVLTSAGCAAGIDLCLHMIRRDH------- +-RPHRVVVLAL------------DGLLPFELGIPHRIFGRPLYEVVTCSIRPGPVE--------DA-----------------------DFA-I-----HTVIVPASYELGPEGVLTGELAAALAH-IRPGTRLASICTGVYVLAAA-------GHLDGRPATTHWADAERFQR---LFP--------------RIKVDA-----DVLFIDDGDVLTSAGVAAGIDLCLHMVRRDH------- +-NPGSVA--VAEDI-------DVPSWDLYELSIPCTVFGKPWYDLRLCSTGQRQQD-SS---TAGA-----------------------GLA-M-----RTVIVPSVPDPCVGRPLPSALITALRHAYDAGARMVSLCTGAFALAEA-------GLLDGRRATAHWMHTAQLAE---RYP--------------KVQVDD-----SVLYVDDGDVLTSAGLTAGLDLCLHLVRRDL------- +-RPHRVAVVAP------------APLSMFNLAIPELLFSKVGYEVAICTPEPGPVPTT----GG--------------------------LA-L-----HTVLVAGTGDRY-PDPR---AVRAVRAAAAAGLRVASLCSGAFLLAEA-------GLLDGRSATTYWQLAAELRG---RYP--------------ALDLKG-----DVLYVEDGRILTASGYAAGIDLCLHMIRSDY------- +-HPHRVAVLAL------------DGVMTFELGIPARIFGTALYAVDVCTPDGASVR--------EA-----------------------GFS-I-----DTVVVAATHRLGVQGVLPEPVAAAVAR-IRPGTRIVSICTGAFVLAAA-------GLLDGRPATTHWAEAEHFRR---LFP--------------RVRFDE-----DVLFVDDGDLLTSAGAAAGVDVCLHLVRRDH------- +-P-HVIAVLVL------------DAVVPFDLGVPAQVFGAAPYEVLFCGEGT--VR--------AA-----------------------GFT-V-----TTVLVPGINA-GGDGTLPEPVRAALHSAADRGARIVSICTGASVLAAA-------GLLDGRPAATHWGWAKRIGG---LYP--------------RVRWDF-----DVLFMDDGDVLTSAGVGAGVDLCLHIVRSDY------- +--PHRVAVLAL------------DGVIPFDLGIPARVLSEALYDIVTCSLDGTQVH--------NA-----------------------GFT-I-----QTIVVATQEPSTAAGELDPRVAELLQT-LDPATRVVSTCTSAFNLAAA-------GLLDGLAATTHWALSDRFAA---LFP--------------AVEVRP-----DVLFVDAGRVLTSAGAAAGIDLFLHIVRTDH------- +-DTNGHGIVRC------------CGHGSGGEAA----IRDDVGARHERGLRAGEVSNDAG---DLV------I---------LAV-AADRH---AETPYDTVMFGAGATI---EPMTPGLIAFSRRALETSRRVAAPCTGAFVLAEA-------GLLDGRRATTHWAFARRLQE---RFP--------------AVKVED-----DRIFIVDGSVWTSAGMTATIDLALAMIEKDH------- +--MMRIGFVVF------------PGFQILDLAAMTVVSHQAVYELHLVSEFGGAVTSSAG----------------------VAV-HTEAF---DEQEYDSVIMMGSIGI---HTPSPGLLGFLQQAHSGSRRIASICTGAFILAEA-------GLLNGLRASTHWRHARELQR---RYP--------------KIKVEE-----DRIFIREGKVWTSAGMTACIDLSLALVEADI------- +-MTKRIALVVY------------PGFQMISLAAMSFEQPAPRYAVSVVSVAGGLVRDSAG----------------------IAV-ATEAI---GRRRFDTVLVAGATRV---VPTQPELAEALVRLASRVRRLGSICSGAFALADA-------GLLDGRRATTHWGQASALQQ---RHP--------------GVIVED-----DRIYVRDGSVWTSAGMTAGIDLALALVEADW------- +--MNQIGLVLF------------PGFQMLDLAAVSLEVRVPAYEIHVVSERGGAVKSSMG----------------------TAI-QTTAM---DPLAFDTLMVGGATSV---PAPSPRLLRLLGHALEPTRRMASICTGAFILAEA-------GILDGRRATTHWHHASTLRQ---RFP--------------AVRVED-----DRIFVRDGTVWTSAGMTACIDLALALVEQDL------- +--MKRVGLVVF------------PGFQILDIVAISLAAPKAAYDIHVVSESGGAVKSSLG----------------------TAV-HTIVL---DPSVYDTLIVAGATTP---QPSSPKLLRVLSRALEPTRRMASICTGAFVLAEA-------GILEGRRVTTHWAHARELQR---RYP--------------SIRVEE-----DRIFVRDGTVWTSAGMTACIDLALALVEGDL------- +-QVHHVGFVVF------------PNFQVMSLAAVSIAIGEAFYGMHLLSEQGGPVLSSAG----------------------FAV-VTEAF---GKRALDTLVVGAATYI---QPSSPGLLDFVRQSVSKSRRVAAPCTGAFALAEA-------GVLDGRRATTHWFFARDLKR---RYP--------------KVRLEE-----DRIFIVDGNLWTSAGMSAVIDLTLAMIEQDL------- +-MAHTVGFFVC------------PGHQILDLAGPLFSAGQDIYETLVLSLNGGSVRGSAG----------------------VSI-ETLPV---DAATLDTLVVVGGDIV---PMSARAEVEAVRRAASRTPRVASVCTGAFLLAEA-------GLLDSRRATTHWQFAGEFQR---RYP--------------RVKLDA-----DRIFVADGHIWTSAGITAGIDLALALIEADH------- +-----------------------SGGPIFESSIPLSVFGIPRYRLLVCGGEAGPLRTTGGL----------------------ELTTPYGLEAI--SRAGTVVVPAWRSITA--PPPPEALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTDH------- +-----------------------SGSPMFESSIPLSVFGVPRYRLLACAGEEGPLRTTGGL----------------------ELRAPYGLGAI--SRAGTVIVPAWRSITG--PPPAAALAALRRAHSEGARIVGLCTGAFALGAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDILTSAGTAAGIDLCLHIVRMDH------- +-----------------------SGGPIFESSIPLSVFGIPRYRLLVCAGEDAPLRTTGGL----------------------ELSAPYGLEAI--SRAGTVVVPAWRSITQ--APPPAALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTDH------- +-----------------------DGLSLFEYGCAVEVFGLEWYRFATCSAEPGTLRGVGGI----------------------QVQADGGLELL--SKAKTIIVPGWRSIDA--VVPPELCRALQKANKRGARVMSICTGAFVLAAA-------GLLDGKRATTHWRHATALAE---RYP--------------EIRVEA-----DVLYVDAGDVLTSAGSAAGIDLCLHLIRRDF------- +----------------------------------------NWYRFMTCSAESGRLRGSGGI----------------------QVQADGGLELL--AKAKTIIIPGWRGIEA--DVPPELCRALRKANKRGARIMSICTGAFVLAAA-------GLLDGKRATTHWRHAAALAA---RYP--------------EVHVEA-----DVLYVDAGDVLTSAGSAAGIDLCLHMIRRDL------- +-----------------------DGLCTFEFGQVVEVFGLDWYRFQVCAERPGPLRATGGF----------------------RVEADGDLAAL--GAAATILIPGWRGIDA--AVPDDLLDTLRTAHARGSRLVSVCSGAAVLAAT-------GLLDGKRATTHWRYAEQLAA---RFP--------------RVQVDA-----SVLYTEADGVFTSAGSSAGLDLCLHLVRRDF------- +-----------------------DGLCLFEFSTALETLGPRWYDVAVASAEATPLRAGGGV----------------------RLAIDGGLELL--EEAGTIVVPGWRAVNE--PVPDALVEALQRAGRRGCRFVSICTGSFVLAAA-------GLLNGRRATTHWHHATVLST---NYP--------------AIDVQP-----AVLYVDEGDILTSAGCAAGLDVCLHLIRRDH------- +-----------------------DGLSLFEYGCAVEVFGLGWYRFATAAAEPGILRGAGGI----------------------EVRADGGLELL--SKARTIIIPGWRGIEE--PVPAGLCLALKKAHKRGARVMSICTGAFVLAAA-------GLLDGKRATTHWRHAGGLAE---RYP--------------SISVEP-----DVLYIDAGDVLTSAGSAAGIDLCLHLIRRDM------- +-----------------------DGIIPFHLSVPYEVFEKPACEITICAAKPGVLKTSAGF----------------------SMIVEEGLAAM--SSKDIIIVPSWDDPAH--QPEACILDALQQAHARGARIIGLCMGAFVVAAA-------GLLDGRTATTHWRWAQCFRD---RYK--------------QVSVDE-----KVLYIDNGDVVTSAGTAASIDCCLHIVRQIW------- +-----------------------DGIIPFHLSVPFAVFEKPLCELTLCAAEPGELKTNAGF----------------------SIVVNLGLGAL--SGMDMVIVPSWDDPAR--QPEPALLDALCHAHAAGATVVGLCMGAFVLAAA-------GLLNHRRATTHWRWLPDFQQ---RYP--------------AVLVEN-----DVLYLDEGDVVTSAGTAAGIDCCLHLVRKRW------- +-----------------------DEIPLFEASVPIAVFGEPEFDVRAVAAEGGPVRTDAGI----------------------ALAAPYGLDAV--DEADLVIVPTWRRPLGR-PPAREALEALRRAHERGATVVGLCLGTFVLAAA-------GLLDGRTATTHWRYAPLLAS---AYP--------------RIQVEP-----DVLYVDGGDILTSAGSAGGIDLCLHLIRRTY------- +-----------------------DGIIPFHLSVPYEVFEKPACEITISAATPGILKTSAGF----------------------SMIVEKGLDEL--SSKDIIIVPSWDDPAH--EPEPCIINALQQAHANGSRIIGLCMGAFVVAAA-------GLLDGRSATTHWRWAQCFRN---LHT--------------NVFVDE-----KVLYIDNGDVVTSAGTAASIDCCLYIVRQMW------- +-----------------------PRLYALDVTIPAYVFGRPGYRVLVCGDSSDESS-VVAA----------------------DIRPTHSLSDM--EGADIVVIPGYENPDE--PIPASYVEALRGAVERGARIVAVCTGVFALAAS-------GTLDGRTATTHWQFTDLLRE---MHP--------------GVDVVE-----NQLFIEDGAILTSAGASAGMDVCLHVVRTDF------- +-----------------------PNVIPLDLSIPAHVLGTDGYDVSVCTED---------------------------------------LTGL--KRADIVVVPGYENPER--PPAEEYLDALSEAHDRGARMVAICTGTFALAAT-------GLLDGRDATTHWKYLDSLRE---LHP--------------LVKVHE-----NRLFVEDGNLLTSAGAGAGIDACLHLIRADF------- +-----------------------PRAYTLDIGIATHVFGRPGYRVLVCAEGTEDADAGTAT----------------------GLGPAHPLSAA--ESADVVVVPGYDDPLL--PLPSSYARTLRIATERGARMLAICTGVFALADI-------GALNGRTATTHWRHTAELRE---NYP--------------EVGVAE-----NRLFVEDGPFLTSAGAGAGIDACLHVVRGDF------- +-----------------------DDIPMFEASVPARVFGGPRFDVLAVAGEPAPLRTSAGI----------------------TLDPPHGLDAL--ESAGIVIVPGWREPGRGEPPSAELLDGLVTAHRDGATVVGLCLGAFVLAAA-------GLLDGRRATTHWAHAATLAH---DHP--------------EVRVDP-----DVLYVDEGSVVTSAGSAAGIDACLHLLRRGH------- +-----------------------QDMPIFEASIPTRVFGPPAHTVLAVAAEPGPLTTSAGI----------------------VVDPPHGLDAL--DAAGTVIVPGWRVPGGA-PAPEALLAALVAARDGGAVVAGLCLGAFVLGAA-------GLLDGRRVTTHWRFAARLAA---DHP--------------RATVDA-----DVLYVDEGDIVTSAGSAAGIDACLHLLRRAR------- +-----------------------QDMPLFEASVPARVFGPPAHTVLAVAGEPGPLSTSAGM----------------------LLDPPHRLDAL--GTAGTVIVPSWRTPDGA-PPSDALLSALAAAADRGATVVGLCLGAFVLAAA-------GLLDGRRATTHWRFAGRLAA---DHP--------------LVTVDP-----DVLYVDGGDIVTSAGSAAGIDACLHLLRRAR------- +-----------------------RDAPLFESSIPISVFGVPYYRLLVCAGEAGPLATTGSL----------------------RVSTPFGLSGA--DQAGTVIVPAWRAPGE--RPPEPALAAVRKAHKEGARLAAFDSGVFVLAAA-------GVLDGRGATTHWMYAPALAR---HHR--------------RVKVDA-----RSMQIDHGDVVTGAGAAAGLDLCLYLVRTDH------- +-----------------------DGVYPFELGIPHRVLGSGRYEVLSASVDGQPVRTDADL----------------------TVVPGHGPEVL--AEADTVVIPPYAVSP----VSDPQALAALSRVRPGTRLVSICTGAFLLAVG-------GFLEGRRAATHWALTDFFQE---LFP--------------RVELDA-----GVLFVDHGDVLTSAGAASGVDVCLHLVRQDH------- +-----------------------DGIYPFELGIPQHVLGSGRYEVVTAGVDGKPVRTVSDL----------------------TVTPGHGPEVL--AEADTVIIPGYAIPQAPAAATDSKALDALSRVRPGTRLVSICSGAFLLAGT-------GLLDGRRATTHWALSDHFRK---LFP--------------RVELDA-----GVLFVDHGDVLTSAGAASGFDVCLHLLRQDH------- +-----------------------DGVYPFELGIPHRVMGSGHYEVLTASVDGQPVRTDSDL----------------------TVTPGHGPEVL--AGADTVVIPPYAISRASAAAPDPRALATLARVRPGTRLVSICTGAFLLAAA-------GLLDGRRATTHWALAADFQE---LFP--------------RVEVDA-----SVLFVDHGDVLTSAGAASGVDVCLHLVRQDH------- +-----------------------EGVYPFELGIAHRVFGSGRYEVRTCTVDGNPVRTDADF----------------------TVTAEHGPEVL--EWADTVVIPPYTVSLAAAELSP-PTARALERIPAGTRIASICTGAFLLAAA-------GILDGRRATTHWALAERFRQ---LFP--------------AVDLDP-----DVLFIDDGTVLTSAGAASGVDVCLHLVRRDH------- +-----------------------SGGPVFENSIPLSVFGVPRYRLLVCAGEDGPLRTTGGL----------------------ELSAPYGLEAL--ARAGTVVVPAWRSITQ--PPPAAALDALRRAHEDGARIVGLCTGAFALAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHMDP-----RELFVDDGDILTSASTAAGIDLCLHLVRQDH------- +-----------------------DGVYPFELGIPNRVFGSGRYEIRTCSIDGRPVRTSADY----------------------AIAVEHDSGLL--ATADTVVVPACDIRMTLDGALPPPVRAAFARIRPDARIVAICTGSFVLAAA-------GLLDGRPATTHWREAARFRR---TFP--------------QVLLDP-----EVLYVDDGDVLTSAGAAAGLDVCLHVVRRDH------- +-----------------------SGGPIFESSIPLSVFGIPRYRLLVCGGEEGPLRTTGGL----------------------ELTAPNGLEAI--ARAGTVVVPAWRSITA--PPPEEALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTDH------- +-----------------------NQLCTFEFGCTVEVFKRPGYEFATFPVDDGPITAAGGI----------------------TIVPTPG--EVLLENADTIIVPGWRGVES--AVPQRLIEQLQAAHARGARICSICTGAFVLAAA-------GLLDGHKVTTHWRYTDLLAT---MYP--------------GLTIQP-----NELYVDQGTIVTAAGSAAGLDMMLHLVRNDH------- +-----------------------DGMTLLDAAGPAEVFSEAGYDVRMVALGAGSVRTSSGV----------------------RIEADA---VTDGTGFDTFLVPGFEGPPA--RDPA-LVAAVRALSEASGRVASVCTGSFLLAEA-------GLLEGRAATTHWRYADLMRR---TYP--------------AVDVQS-----DAIFVRAGKVFTSAGVSAGIDLALALVEDDH------- +-----------------------DEVDILDVMAPYEVLLAATIDVRFVSIDERR-----TFKNGI-SN--------------YELQAETTL---DTQTTGLVLIPGASGSINMKIANQGVTDKIKEVHRPNMTIASVCGGGVLLAMA-------DIIKDRHVTAHFMGLDLL-------------------EGAGAHVV------NARVVDDDDIVSGAGVTSGLDLAFYLVEREL------- +-----------------------DGFDLMDALAPYEVFAAAAMTVELVSAEGKR-----SVPSGM-KG--------------PAIEAQAAL---DPSRSGIILVPGGSGKPEGLAMESDLTSLMKQALEEHITVATVCGGSLVLAMG-------GLLEGRNAVTNHLGMSAL-------------------GATGAIPI------EARVVEDRRLVSGGGVTSGLDVALYLVEREV------- +-----------------------NGFDLMDAIAPYEVFAAAAMTVELVSAEGKR-----SVPSGM-NG--------------PAIEAETVL---DPSRPGIILVPGASGKPEGLAMETELTPLMKRAFEKDVTVATVCGGSLLLAMG-------GLLEGRHAVTNHLGMAAL-------------------GATGAIPI------AARVVEDGRLVSGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFNAAAITVKLVSAEGER-----MVTSGV-NH--------------LQIQANGKL---DLTSNGIILIPGASGSVHDQAAETELGNLLNEAMQQAILLSTVCGGSLILAMG-------GLLEGRHAVTHHMGMGLL-------------------GATNAIPV------NARIVDDGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFSAAELRVTFVTAEGPR-----AVTSGI-NG--------------VKLEASGKL---ALEHPGILVVPGAAGGIEGRTANTELTPLLQQALGPDAIVATVCGGSLVLAMG-------GLIEGRPAVTHHLGMEAL-------------------AATGAVPI------QARVVDDGNLVTAGGVTSGLDLALYLVEREL------- +-----------------------DGFDFMDVIGPYEVFMAAKVTVEFVSAEGKR-----HVTSGM-NG--------------PGLPSSGKI---DLEREGILVIPGVFASVNDRAMETDLIHFLREALYTDLIVSPVCGGTLILAMD-------GLLEGRHAVTHHMGMEFL-------------------GATGAIPV------HARVVDDGNVVSGGGVTSGLDLALYLVEREL------- +-----------------------DGFDLLDAMAPYEVFCAASLQVEFVTAEGPR-----LVTSGI-NG--------------LQIEATGGL---NPERADIILVPGAAGDVEGRAANTELTRLIQQALGGDVVVATVCGGSLLLAMK-------GLLEGRPAVTHHLGMDVL-------------------GAAGAIPV------SARVVDDGNLVSGGGVTSGLDVALYLLEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVEFVTAEGPR-----SVPSGI-NG--------------LKIEAKGRL---NPERGGIILVPGASGDIEGRAMNTELTGLVGQALGQDAVVATVCGGSLVLAMG-------GLLEGRPAVTNRLGMDLL-------------------GATGAIPV------PARIVDDGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIGPYEVFCAAGVTVELVSAEGAR-----EVPSGM-NG--------------PAIAATHWL---DPYRPGIIVVPGASGHLQGKATETPLAGLLKQAMEKDTTIATVCGGSILLAME-------GLLDGRYAVTNHLGMEVL-------------------QAAGAIPV------QARVVEDGRLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDALAPYEVFCAAELNVELVTAEGPR-----SVISGT-KG--------------LAIEASGRL---NPEQAGIILIPGASGDPTRRAMNTELTGMIGHALEKDIIVATVCGGSLLLAMG-------GLLESRPAVTHHMGMDAL-------------------GATGATPV------RARLVDNGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIVPYEVLNAAGLNVELVTAEGAR-----SVQSGI-SG--------------LEIRASGKL---NPEHAHIIIVPGAAGEVSGRAAETELTNLVRSGLNQDLVTVTVCGGSLLLAMG-------GLLDGRHAVTHHLGMDVL-------------------GATGAVPV------SARVVDDGNLITGGGVTSGLDVALYVVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVELVTAEGSR-----AVASGV-KG--------------LKIEASSRL---NPECAGIILVPGASGEVDGRAMNTELTGMIGQALDQDIVVATVCGGSLLLAMG-------GLLEGRSAVTHHLGMDLL-------------------GATGAVPI------KARVVDDGSLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVELVTAEGPR-----SVPSGI-NG--------------LKIEASGRL---DPECAGIILVPGASGDVEGRASSTEIPGLIKQALGRDIVVATVCGGSLVLAMG-------GLLEGRPAVTNRLGMDFL-------------------GATGAVPV------PARVVDDGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFHAASFSVEFVTAEGPR-----SVKSGV-ND--------------VLLEAKEKL---DPTRPGIILVPGAAGAVDGRAMNTELTRMVEHALHKDMVIAGVCGGSLLLAMG-------GLLEGRHGVTHHLGMDAL-------------------AATGVTTV------QARVVDDGNFVSSGGVTSGLDLALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVEFVTAEGPR-----IVTSGI-NG--------------LKIEASGRL---NPERTGIILVPGASGDVEGRALNTELAGLIERALGKDIIVATVCGGSLLLAMG-------GLLEGRPAVTHHLGMNVL-------------------GATGAIPV------PARVVDSGDLVTSGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALNVELVTAEGAR-----SVASGI-NG--------------LRIEATGRL---NPDRAGIILVPGASGDVMGRAMQTELTGLIRQALVKDVIVATVCGGSMLLAMG-------GLLEGRPAVTNHLGMDLL-------------------GATGAIPV------WARVVDDNNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVEFVTAEGPR-----SVTSGI-NG--------------LKIEASGRL---NPVRAGIIFVPGASGDLEGMAMNTELTGMIGQALGKDIVVATVCGGSLLLAMG-------GLLEGRPAVTHRLGMDLL-------------------EATGAVPV------SARVVDDGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAALSVELVTAEGPR-----SVTSGI-NG--------------LKIEASGTL---NPERAGIILIPGASGDVEGRAMNTELTGMIGQAIRKDIVIATVCGGSLLLAMG-------GLLEGRPAVTHHLGMDVL-------------------GATGAIPV------PARVVDSGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLMDAIAPYEVFHAAALEVELVTAEGPR-----SVTSGT-NG--------------LKMEASGRL---DPKHEGIIVVPGASGDVEGRAMNTELTPMIREALDKDIVVATVCGGSLLLAMG-------GLMEGRHAVTHRLGMDLL-------------------GATGALPV------PARVVDDGNLVTGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFNSAVVSVEFVTAEGPR-----SVTSGI-NG--------------LKIEASGRL---NPQQAGIILVPGAAGDVEGRAVQTELTGLMEQALRQDIIVATVCGGSLLLAMG-------GLLEGRKAVTHHLGMDVL-------------------GATGAVPV------PARVVDDGNLVSGGGVTSGLDVALYLVEREL------- +-----------------------DGFDLLDAIAPYEVFCAAAINVELVTAEGPR-----SVPSGI-NG--------------LTIEASATL---DPNRSGIIVVPGASGSVEGRAMNTDLTEMIRQALGKDIVVATVCGGSLVLAMG-------GLLEGRPAVTNHLGLDLL-------------------AATGAVPI------SARVVDDGNLVTGGGVTSGLDVALYLLEREL------- +-----------------------DGFDLLDAIAPFEVFSAASVSVQFVTAEGPR-----SVTSGI-NG--------------LNIEASGTL---DPEQSGIILVPGASGEIEGRAVHTSVIDLVARALGQDVIVATVCGGSLLLAMG-------GLLEDRPAVTHHLGMELL-------------------GATGAVPV------PARVVDHGNLVTGGGVTSGLDVSLYLVEREL------- +-----------------------PGMTALDMIGPYEVLRAPDAEVRFVWHEPGPIVTDSGVL---------------------LFGATHSFAET--SRPDIVLVPGSGTSTASTARDEALLAWLREVHETTRWTLSVCSGSVILAAA-------GLLRGKKATSHWRALDLL-------------------RPFGASPQP-----HSRIVSAGKITTAAGVSAGMDLALFMVG---------- +----------------------FDGAEELDAIGPWEVLRFRRVDVRAVSLDGKSVRCAKGLT----------------------VDVDGSLGD---RPIDLLIVPGGRGA-DILAGDLEQVGRISRLAEQGATMASVCTGAQVLGAA-------GLLDGINATTHWMARGQLQK------------------SHSARISS-----GERWVDSGDVVTSAGVSAGIDMALHLVDRF-------- +------------------------------------------------------------------------------------------------------------------------------QADKVKYIVSVCTGSLLLGAA-------GFLKYKKATTHPNAYELLEP--------------------YCEEVI-----KSRIVKDGNLITAGGVSTSIDLALYIVSLLV------- +------------------------------------------------------------------------------------------------------------------------------HHDAGATVAAVCTGGMLLAAA-------GLLDGRPAVTHAGAVADLR----------------------ADVRD-----EARLVDDGDVLTAGGVTSGLDLALHLVEREA------- +------------------------------------------------------------------------------------------------------------------------------QSQPGRVIAAVCTGAFLLAKT-------GKLAGKQVTTHWEDINDLKP--------------------SVDVLS-----TLRWVDEGSFVTSAGISAGIDMSLHLVERLH------- +-------------------------------------------------------------------------------------------------------------------------------------MASVCTGALLLTKA-------DLLNFKRATTHWASIASFRP--------------------NVEVLE-----NVKFVDEGHIITSGGILAGMNMSFHIVKNLL------- +------------------------------------------------------------------------------------------------------------------------------VDKHAKHIASVCTGAFILANA-------GLLKGLAVTTHWEDIPELKP--------------------DLVVVE-----DKRWITASKYTTSGGISAGIDMSLFLVSKFH------- +-----------------------AGFRLLEVSGPMAVFGEANYEQHLVGLSPGPVVCSNGA----------------------AVVTTEALTQG-HGSFDVVLIPGSPSV-GAGQEHPELVTWLKQIGRDARRLASVSNGAFLLARA-------GLADHRWLTTHPDDARRLAS---EYP--------------LVHVMT-----DLSCLKDGNLYSAGGVRAGIRLALTLVQED-------- +-----------------------TGFQLLEVSGPMDVFHQANYEQHLIGPAPGTVLSSNGT----------------------AVRATGCLLDT-RTPFDIIVVPGAQAV-GSAREHRELVDWLSDAGPKTRRLASISNGAFLLARA-------GLADGRWLTTHWRDAHRLAT---EYP--------------LVHVMS-----NPGCLKDGNLYSSGGASAGIHLALAFVRED-------- +-----------------------AGFQLLEVSGPMDVFEEANYVQHVIGPTLGPVMCSNGT----------------------AVRTTESLRDL-RTSFDIVIVPGSPAV-GSAREHRELVSWLGGVDGSATKIACISNGAFLLARA-------GLADHRSLTIRECDAHRLAR---DFP--------------LVHVVP-----DAGWLKDGNLYSSDGVSAGVGLALTLVEED-------- +--PKKVGILLY------------HAVEPLDFVGPYEVFSAARYDVFTVSENKGDVKSSSGL----------------------IVKADYDFTDC--PQADIIVIPGGNLT-PELLGNSTIISWIQTQNKNAEITFSVCSGALLAAKA-------GLLAGMSATTHHMCFDKLLEID---P--------------TIILNK-----TERFIDNGSIITAAGVSAGIDAALYIVYK--------- +-----------------------PGFQLLDFAGPMDAFNILSYDLTLYTITLDPVS-----THNFLQK-------ERGSQISQTLVPTHTFDTA-PDDLEVLLIPGGLGARS-KEQMKPVVEYLEKLDMSLRWVLTVCTGSEILART-------GVLDGRRATTNKKAFNDV-------------------KATRVEWVP-----KARWVVDGNFWTSSGISAGMDLAFAWIAHV-------- +---------------------INDATETTDYLVPTGILRRADADVVTLATGPGPVRLF----PA------------------LTVEADATLDAFNPAGADYVIVPAMSR-----DDDPAVLAWLREQARKGATIIGVCAGAKVVAAA-------SLLDGKRATTHWYYLKELL------------------GRHSIRYVA-----DRRVVADRGVVTTTGVTASMPMTLLLIEA--------- +---------------------INDATETTDYLLPHGILKRADAEVVSIATGPGPVRLF----PA------------------LTVQPDMTIADFYPEGADHVIVPAMSR-----DDDPVVTDWLRDQARKGAVIVGICAGAKVLAAA-------GLLKGKRAVTHWYYLDRLR------------------KIDTIAHAP-----DRRMVADGGVVTTTGITASMPMMLTLVEA--------- +---------------------INDGTETTDYLVPTGILRRAGADVVMVAAEPGPVLLY----PA------------------LKVEPDTTLSVFHPEGADYVIVPAMSR-----DDDPAVMAWLQQQSAKGAIVIGVCAGAKVVGAA-------GLLDGKRATTHWYYLKDLL------------------RRSTIDYVA-----NRRFVVDGNVVTTTGITASMPMMLTLIEA--------- +---------------------LNNATETTDYLVPSGILRRAGADVMMLATGPGPVTLY----PA------------------LRVVPDATLAQFHPEGADYVIVPAMSR-----DDDPAVLAWLTSQAAKKARIIGICAGAKVVAAA-------GLLDGRRATTHWYYLREML------------------RWSTTTHVA-----DRRMVSDEAVTTTTGISASMPMMLTLIEA--------- +----------------------------------------------------------------------------------------ERLDSLDAEPIDTLIVPGVPID-EHCTLQPELVAWIRRNAPRARRICSVCTGAFYLAAA-------GLLDGRRATTHWREAAHLAR---RFPNVHPIFI----RDAGSGAG--SDGHTSTTPRESVVWTSAGVTAGIDLALALIDED-------- +----------------------------------------------------------------------------------------ERLDSIDIATIDTLIVPGVPID-DSTVLQPELVAWIAAAAPHARRVASVCTGAFYLAAA-------GLLDGRRATTHWRNAAQLAR---RFPRVNPIFV----RDERD---------------GRVVWTSAGVTAGIDLALALIEED-------- +----------------------------------------------------------------------------------------ERLDSLDDQPIDTLIVPGVPID-EHCTLQPELVAWIRRRAPEARRVCSVCTGAFYLAAA-------GLLDGRRATTHWREAPHLAQ---RFPNVQPIFI----RDVGHGEG------------KRVVWTSAGVTAGIDLALALIEED-------- +----------------------------------------------------------------------------------------ERLDSLDDQPIDTLIIPGVPVD-EHCTLQPELVAWIRRHAPRARRVCSVCTGAFYLAAA-------GLLDGRRATTHWRDAPQLAR---HFPNVQPIFI----RDVGRGAG------------ERVVWTSAGVTAGIDLALALIEED-------- +----------------------------------------------------------------------------------------ERLDSLETEPIDTLIVPGVPID-PHCTLEPELVAWIRRNAPRARRVCSVCTGAFYLAAA-------GLLDGRRATTHWREAAQLAR---RFPNVQPIFI----RDAGPGAT--D----SASSHPGAVWTSAGVTAGIDLALALIEED-------- +----------------------------------------------------------------------------------------ERLESLDAEPIDTLIVPGVPVD-EHRPLQPELVAWIRRNAPRARRVCSVCTGAFYLAAA-------GLLDGRRATTHWRDAAQLAS---RFPNVHPIFI----RDAGSGAG------------AGVVWTSAGVTAGIDLALALIEED-------- +----------------------------------------------------------------------------------------ERLDSLDDQPIDTLIVPGVPVD-EHCTLEPELVAWIRRHAPRARRVCSVCTGAFYLAAA-------GLLDGRRATTHWRDAPRLAQ---RFPNVHPIFI----RDAGRHEG------------DGVVWTSAGVTAGIDLALALIEED-------- +-----------------------RGVQALDVVGPCDVFTAAGYAVSVVSRGGAPIATGTGLE----------------------LAA-RPLPDP-RRPVDTLVLPGGFGV-DEARSDPELIGWLRLAAEHARRTVSVCTGAFLAAQA-------GLVDGCAVTTHWAFADRLAA---EFP--------------SVTVDP-----NPIFVRSDRVWTAAGVTAGIDLALALVEDD-------- +-----------------------DNIEILDFAGPMEVFVVAGFNVYTVAKTTQPMKAM-----HY-----------------LTVVPDYSIDNA--PIPDIAVFVGGGNL--SATKDEKVKNWVKKVTPQSKLKFTVCTGAFFLAEA-------GFLDHKIATTYHKSIDYLQS---------------EYP--KIDVRK-----DVRFVDNGEVITTAGISAGIDGALHLVSK--------- +-----------------------DGVELLDFSGPGEVFAAASFNVYTVAKE-KELTSQ-----DF-----------------LKITPNYNLNKA--PKTDILILPGGYAG--ESINDVSTQKWIDSQWYKTPHVLTVCSGIYFLEKP-------GKLKDIKVTSHHKIIPFLKE---------------SLG--GDNVIE-----EVKYVDSGKIVTSAGVSSGIEGALLMVSK--------- +-----------------------DGTEVLDFAGPMEVFSYAGFKIFTVGKTKAPVT----VQ-GI-----------------LKVIPDYSIADAPPANYFAI--FGGDDGIA--TNDPEVISWIKKRDATTEGYFSVCTGAFVLGKA-------GLLDGLTVTTFHNSIQNLQG---------------AVP--SAKVLN-----NVRYVDNGRVITTAGISAGIDGALHLVARL-------- +-----------------------------------------------------------------------------------KVDPDFSISDH--PPMDCLIVPGGVVNA--EMEKADVIRWISDQSEPGRVVAAVCTGAFMLAKT-------GKLAGKQVTTHWEDIGDLKE---MFP--------------SVDVLS-----TLRWVDEGSFVTSAGISAGIDMSLHLVERLH------- +-----------------------QAFEILDVFGPLEALNMRHLEMFLISETMDPVATKPVMAP----------MNPFDSTFWPTLPPTHTLETV-PGDLDVLIIPGGLGVR--SPNINATLTYLADTYPKLQYLITVCTGSALAARA-------GLLDGRRATTNKAQWDSTVA-------FGP----------NTTWVS-----QARWVADGNIWTSSGISAGIDVTLAFIEES-------- +---------------------------------------------------------------------------------GPRLTPDKTFGEA-KEQFDIIMVPGGIPE---V--PQELNDFLIRQVPGAKYVLTICTGSWVLART-------GLLDGKRATGNKFVFKEML--------------AD-TASHSIQWVA-----RARWVVDGKFWTSSGVTAGADMASAFVTQ--------- +----------------------FPGFQALDAFGPLDALNILSYSLSLIGATLSPISTTPSQQP---------------SAIGQTIIPTHTFSTA--PPLDVLLIPGGYGTRGSPPGLEDAIDFIRSRFPELKYMITVCTGARLAARA-------GVLDGLRATTNKRAWLDTRE----------------M-APGVKWVA-----HARWVVDGKCWTSAGVSAGIDVVLAWMEEV-------- +----------------------YPGFEPLDIFGPLEAFYSAGYEVGPVSAKPGVIPTTEPLDPGWLA--------------APSIYATHTFHTA--PALDILLVPGGTGDFYDGYKITDVEDFIRARYPALNYLLSVCSGAVNLARA-------GVLNGKRATTNKALWQWATD-----P----------SRGKNITWVP-----AARWVTDGNIWTSSGVSAGLDMTYAFMK---------- +-----------------------DGFQALDVFGPLXVLNMLSRTHGLLSVLAAPVST-RTPDM--A----R-------QRIGQHVVPTHTLQHP-PQDVEVLLVPGGRGT-RDAAARAAEVAYIRAAFPRLRFLLTVCTGSALAARA-------GVLXGRRATSNKVSFGWPGSPGGAA----PNGVQVTTQGPKVHWVR-----HARWVDDGN----------------------------- +-----------------------PGFQALDVFGPLDALNVLSYTTPLLSIILSPIST-H-PAS--Q----P-------TAIGQTIVPTHTFSSA-P-PLDVLLIPGGYGT-RGSPPGEDAIDFIRSRFPKLKYMITVCTGSRLAARA-------GVLDGLRATTNKRAW--L---------------DTREMAPGVKWVA-----HARWVVDGK----------------------------- +-----------------------PDYQWLDSAGPVDYLNNHSQARLTSDPKKAPILT-WTLDP--V----R-------ASSGPTQPPTHTFETC-P-PVNYVLMPGTLLN-PTLPPS--FVKFVQERYPSV-TFLTVCTGSLTLAPT-------GILDHHRVASNKGALKYLAQS--------------GQLNHKVHWVG-----DRRWVKDGK----------------------------- +-----------------------PCFQLLDAVGPFDMINSSSKEYVNLYPPKAVSYT-WDLTP--I----S-------ATSGPLLQPTCTIKDC-P-KLDYLLIPGPDPT-GPFPEE--TLAFIRKVS-EAKEVLTICTGSMVLAAA-------GVLDGRRACTNKFALKALAAE--------------GKHRKEVKWVT-----DKRWVVDGK----------------------------- +-----------------------PSYQLLDAVGPFDYINNHTQSYLKIPDAKGAHIV-WDLAP--V----Q-------PSSGPPQNPTCTYADC-T-PLDYLIVPGPDPT-APLPAG--CAAFLQRLMDTFKALLTVCTGSAAAAQS-------GVLDGRRVCSNKYVLRVLAGA--------------GALNRRVRWVG-----DARWAVDGK----------------------------- +-----------------------PDDQNLDVVGTMDYLNNHSQAYLAAVQHKAPILT-WNLDP--I----N-------GQLGPVRSMPCG-------------------------------------------------LYPLLAQT-------GVLDGYHVASNRMALKFAVDA--------------GKLNKAVHWVG-----DARWDQDGR----------------------------- +-----------------------PGYQWLDAAGPVDYINSHSRPMISLAPTKAPIMT-WGLTP--I----R-------STSGPLQQPNCTFDTC-P-PLDYLVVPGADAF-EPLPEG--CADFLRKLIPTFKALLLVCTGSMSVAQA-------GILDGLNVCSNKLSLKIAAEK--------------GLLNRKVKWVG-----DRRWIVDGK----------------------------- +-----------------------DSFQWLDAAGPVDYLNNHSYPMISLPQSKAPIIN-WDLTP--V----Q-------ATSGPPQVPTCTFDDC-P-PLDYIVIPGGEPT-MTISPE--FASFVKKRVPGMKTLLLICTASLAIAQT-------GILDGRQTCSNKMALKSLAEV--------------GMFNRKVKWIR-----DRRWIKDGK----------------------------- +-----------------------PQHQLLDAAGPVDHINCHSRTYLELPPSKAPIIT-WNLDP--V----A-------TSAGPLQIPSTTLADC-P-PLDYLLVPGADPR-IPLSEA--TCTFLKARF-EVKGLLTVCTGSLVVAQT-------GLLDGLNVASNKVVLLMLASQ--------------KSLNKNVKWVG-----DRRFVRDGK----------------------------- +-----------------------PEYQWLDAAGSVDYINTHSYQILSLSPAKAPIMN-WDLTP--I----R-------STSGPLQQPSCTYDTC-P-QIDYLVVPGPDPF-VPLPEG--CAGFLQKLIPSFKALLLVCTGSMAIAQT-------GILDGLNVCSNKVALKMAVDR--------------GLLNKNVKWVG-----DRRWIVDGK----------------------------- +-----------------------PFYQLLDAVGPFDYLNNHSQAYLKIPDEKGPIIV-WDLNP--I----Q-------PTSGPPQHPTNTYADC-P-ELDYLIVPGPDPA-TPLPEG--CTAFLQNLIDTFKALLTVCTGSIVVAQC-------GILDGLSVCSNKMVLKIVAGA--------------GLLNKNVKWVA-----DKRWNIDGK----------------------------- +-----------------------PSYVLLDAVGPTEYINSHTQEALKIPEEKGATIV-WDLNP--V----Q-------PSIGSPQIPTATYRDY-P-ELHYLIVAGGDPT-AILPEG--CTAFLQDLIDTFKGLLTVCTGSILVAQS-------GILDGFSVCSDKYALRTLALA--------------GTLDKKVKWIG-----DKRWNVDGK----------------------------- +----------------------FPGFQALDVFGPLDALNVLSYSTSLIGASLSPIST-HPAA--------------QPSAIGQTVVPTHTFTSA--PHLDVLLIPGGYGTRGSPPGLEDAIAFIRSRFPELKYIITVCTGARLAARA-------GVLDGRRATTNKRAWLDTRD----------------MAP-EVKWVA-----HARWVVDGKCWTSAGVSAGIDVVLAWMEEV-------- +-----------------------DGVTMLDVSGPGEVLHQAGYAPVLVSPRGGNVATSSGLV----------------------LAGTTA--AADAGRLDTVVVSGAGR-LTEPELDDELLATVRALAGGARRVASVCTGAFVLAEL-------GLLDGRRATTHWRHARTLAS---RYP--------------RVQVEP-----DVIHVRDGRYITSAGITAGIDLALALVEDD-------- +-------------------------------------------------------------------------------------------------VFDTVMFASGVETA---FASPALNGFVKHALKTSRRVAAPCTGAFVLAEA-------GALDGRRATTHWRFAGDLKR---RFP--------------KVAVEE-----DQIFIVDGSIWTSAGMAATIDMALAM------------ +----------------------------------------------------------------------------------------------------------------------------REVAARGTRIASICTGAFPLAAT-------GLLDGLRATTHWAAAALLAE---TYP--------------AVEVDP-----DVLHVDNGQFLTSAGAAAGLDLCLHLVRRDY------- +----------------------------------------------------------------------------------------------------------------------------HLAAPHARRVASVCGGALLLAQA-------GLLDGRRATTHWRLLETLKT---RYP--------------AVNVEG-----GPLYIQDGPVWTSGGVSSGFDLTLALVEDDY------- +----------------------------------------------------------------------------------------------------------------------------AGYYKNGGEVASLCVGAALLAAG-------GVLDGQRAVVHWAAQSDFGR---LFP--------------AVRWVS-----DRVVLEANGIYTSGGAFSAAHLVLHLVDKYT------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEDVPLRTTGGL----------------------ELTAPYGLEAL--SRAGTVVVPAWRSI-TQ-PPPPAALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEDVPLRTTGGL----------------------ELTAPYGLEAL--SRAGTVVVPAWRSI-TQ-PPPTAALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDILTSAGTAAGIDLCLHIVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCGGEEGPLRTTGGL----------------------ELTAPHGLEAI--SRAGTVVVPAWRSI-TS-PPPEEALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEDAPLRTTGGL----------------------ELSAPYGLEAI--ARAGTVVVPAWRSI-TQ-APPPAALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEDGPLRTTGGL----------------------QLSAPFGLEAI--SRAGTVVVPAWRSI-TQ-PPPQAALDALRRAHEEGARIIGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------AVHVDP-----RELFVDDGDILTSAGTAAGIDLCLHVVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLACAGEDGPLRTTGGL----------------------QLTAPHGLEAL--SRAGTVVVPAWRSI-TQ-PPPAAALEALRQAHEEGARVLGLCTGAFVLAAA-------GLLDSRPATTHWMYAPTLAK---RYP--------------AVHVDP-----RELFVDDGDILTSAGTAAGIDLCLHVVRSD-------- +-----------------------------------------------------------------------------------AVQATHDFAN--APALDIIMVPGGLGL-NHLTNDTAIQDFINLRYSQAQYILSVCTGSQVLASA-------GILDGRKATTNKAAWKSVVG------------------SREVDWVP-----TARWVEDGNVWTSSGVAAGIDMMYAFLKH--------- +----------------------FPGFQALDVFGPLDALNVLSYSLSIIGATLSPIST-HPAAH--------------PTAIGQTVVPTHTFASA--PHLDVLLIPGGYGTRGSPPGLDEAIDFIRARFPELKYMITVCTGSRLAARS-------GVLDGLRATTNKRAWLDTRE----------------MAP-AVKWVA-----HARWVVDGKCWTSAGVSAGIDVVLAWMEKV-------- +--------------------------------------------------------------------------------------------------PDILVVPGGYGT-RQVLEKRDIIEWIQLVSKEAELVLSVCTGSLVLAKA-------GILEGLQATTHHQVLDTLASL----------------AP-NTKIIN-----DKRYVDNGSIVTAAGIS--------------------- +---------------------------------------------------------------------------------------------------------------------------------------SVCTGVFYYAAA-------GLLHGHRVTTFHGEIERLRQ---EAP--------------QTEVLT-----GVKYVDSGNIVAAAGVSSGIDGALYLVERLE------- +---------------------------------------------------------------------------------------------------------------------------------------SVCTGVFMLNEA-------GLLDGKRVTTHHLAAGMLQR---SNA--------------SLQVES-----ESKVVHDGNIVSSGGVTSGINMALYLVRTIL------- +-DMKTILVIVP------------DGGMLFEAAGIADILMQARYRISIATTQPHHV------VHGM-S--------------GLNLLADHRLADLDPNPRDTIMVTGK-GQ--SEPEGSAVVEWLCRAAPNTQRIASVCGGAMLLARA-------GLLDGRRATTHWRMLEEMQA---RWP--------------QIKVEG-----GPLYIQDGPVWTSGGVSSGFDLTLALVEA--------- +----------------------------------------------------------------------------------------------------------------------------------GGRPAAISTGPFALAPT-------GLLDGRRATTPWHYTRALVA---RHP--------------LVQVDQ-----NVLFVDEGSVLPSAGAASGIDLCLPILRG--------- +----------------------------------------------------------------------------------------------------------------------------------GARLCSICSGVFVLAAA-------GVLDGLTVTTHWRYAEKLQA---RYP--------------ALRVNP-----DALYVDEGQIVTSAGSAAGLDMLLHLVRR--------- +----------------------------------------------------------------------------------------------------------------------------------GLRIASICSGAFVLAGA-------GLLDER-TTTHWMHATALAT---RYP--------------RVRVAP-----DVLYHQDGNIWTSAGTAAGIDLRLELIRR--------- +-----------------------PAFQSLDVFGPLDALNMLGYNLYIIADTLDPVPTR--VK-D---A-------SHISNFCESVVPTHTFQTA--PPLDVLIVPGGQGTRN--PGISTAIDFVKERFASLQYLLTVCTGAGVAARA-------GVLDGRKATTNKLSWDQTIT----------------LRP-QVDWIH-----KARWVQDGNVWTSSGISAGIDLAFAWIGA--------- +--MYKIGVVLF------------DDFTDVDFFLMYDLLGRTTWTVSILGTK--SEH--HS-------------------HLGMKVKTDGHLSEVT--NQDVVLITSGKRGIPAALKDAEFMSALN-LDPNRQLIGSICAGSFILHEL-------GLLKGKRLTTNPDAKAV-------------------LQSMGGDVQD------LPLVIDGNVATAGGCLSLMYL---------------- +--MYKVGIVLF------------DDFTDVDFFLTYDLLGRTSWTVSVLGTK--SEH--NS-------------------HLGMKVKMDGHVSEVV--NQDVVLITSGKRGIPAALKDLGFMSALN-LDRNKQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKTV-------------------LESMGGDVQD------LPLVIEGNIATAGGCLSLMYL---------------- +--MYKVGVIIF------------DDFTDVDFFLMYDLLGRTTWTVSILGTK--PEH--HS-------------------HLGMKVRTDGHISEVT--NQDVVLITSGKRGIPAAMRDAEFMSALS-LDPNKQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKDV-------------------LQKMGGDVQN------LPLVVEGNIATAGGCLSLMYL---------------- +--MYKVGVVLF------------DDFTDVDFFLMYDLLGRTSWTVSILGTK--PEH--YS-------------------HLGMKVKTDGHVSEVT--NQDVVLITSGKRGIPAAMKDTGFMSALN-LDPTKQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKSV-------------------LKNMGGDVQD------LPLVVEGNVATAGGCLSLMYL---------------- +--MYKVGVVLF------------DDFTDVDFFLMYDLLGRTSWTVSILGTQ--PEH--YS-------------------HLGIKVKTDGHVSEVT--SQDVVLITSGKRGIPAAMKDCEFMSALN-LDPNNQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKRA-------------------LQSLGGDVQD------LPLVVQGNIATAGGCLSLMYL---------------- +--MYKVGVVIF------------DDFTDVDFFLMYDLLGRTTWTVNILGTK--PEH--HS-------------------HLGIKVKTDGYISEVT--NHDVVLITSGKRGIPAAMKDTRFMSALN-LDPNRQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKSV-------------------LQSMGGDVQD------LPLVIEGNVATAGGCLSLMYL---------------- +--MYKVGIVLF------------DDFTDVDFFLMYDLLGRTAWTVSILGTQ--PEH--RS-------------------HLGMKVKTDGHICAVA--DQDAVLITSGKRGIPAAMKNTEFMSALN-LDPKKQLIGSICAGSFILHEL-------GLLKGKPLTTNPDAKTA-------------------LQSLGGDVQD------TPLVIEGNIATAGGCLSLMYL---------------- +--MYKVGIVLF------------DDFTDVDFFLMYDLLGRTTWDVRILGTK--AEH--NS-------------------QLGITVKTNGHISEVK--DQDVVLITSGYRGIPAVLQDENFMSVLK-LNPKKQLIGSICAGSFILHEL-------GLLNDKKLTTNPHAKAT-------------------LESMGGDVQD------LPLVIEGNIATAGGCLSLMYL---------------- +--MYTVGIVLF------------DDFTDVDFFLMYDLLGRTQWTVKVLGTK--PEH--DS-------------------HLGMTVKTDGHISEVA--TQDVVLIASGKKGIPAALQNSEFMSAMK-FNPEKQLIGSICAGSFILHEL-------GLLDGKKLTTNPDAKAV-------------------LKSMGGDVQD------VPLVVEGNIATAGGCLSLMYL---------------- +--MYKVGIVLF------------DDFTDVDFFLMYDLLGRTTWDVKILGTK--AEH--NS-------------------QLGISVKTGGHISEVR--NQDVVLITSGYRGIPAALQDKNFMSALK-LDPKKQLIGSICAGAFILHEL-------GLLTGKKLTTNPHAKAA-------------------LESMGGNVQD------LPLVVEGNIATAGGCLSLMYL---------------- +--MYKVGIVLF------------DDFTDVDFFLMNDLLGRTSWTVRILGTK--PEH--HS-------------------QLGMTVKTDGHVSEVK--EQDVVLITSGYRGIPAALQDENFMSALK-LDPSRQLIGSICAGSFVLHEL-------GLLKGKKLTTNPDAKAV-------------------LQGMGGDVQD------LPLVIEGNIATAGGCLSLLYL---------------- +--MYKVGIVLF------------DDFTDVDFFLMYDLLGRTTWEVKVLGTK--PEH--RS-------------------HLGMTVKTDGHLSEVA--QQDVVLITSGYRGIPAALKEPEFMNSLQ-LDPSEQLIGSICAGSFVLHEL-------GLLKGKRLTTNPHAKPT-------------------LEAMGGDVQD------LPLVIEGNIATAGGCLSLVYL---------------- +--LKKIVLVAF------------DQFTDIDLFLMWDILGRNTWHVRILGSS--AIV--RS-------------------AHGLPVSVHGPLSEAN--SADAVLFVSGKEGIPAALAAPDFLPSFE-LDSRRQRIGSICAGAFILERL-------GLLSGQA-TTHPDARSS-------------------LQALGLEPVD------QPLVCQGNVATAGGCLSALYL---------------- +-----------------------------------------------------------------------------------KLVADASWAVCDPATLDTLLVPGGVGV-DAQKHDQPLLDWLRAAEPRVRRLGSVCSGALILAEA-------GLFDGRKATTHWADLAALG----TYPT---------IEVQGDRLHTY-DPTDP---QAAHLFSSAGVTAGIDLALFWSCS--------- +------------------------------------------------------------------------------------------------APVDTLVIAGGPGVV-AACGDVALVAWVRDRAARARRVASVCTGAFLLGAA-------GLLDGRRAVTHWKHCGALAA-----------------RHPRVRVEP-----DPIFVRDGPVWSSAGVTAGIDLALALVEED-------- +-----------------------------------------------------------------------------------SLVPSKTFDQVRGTQYDIILVPGAAGRVAG-EVSSTIVNFVKNQNPGLKYLLSVCTGAWIVANA-------GVLEGKNATTNKAAFMRIKN---------------E-TSTNINWIP-----KARWVVDGNTWTSSGVSAGADMAHAFMEYL-------- +-----------------------PGFQALDVFGPVDILNMTPLELSIIAETLDPVSTK---GEG----P-------KTATIGQSVVPTHTFQN-PPSDVEVLLVPGGGGT-RNAERTKPIIEYLQQTYPKLRYLLTVCTGSALVARA-------GLLDGHEATSNKRSFSWV-------------------TAQKVNWIR-----EARWVTSGNFWTSSGISAGIDMMFAFVAS--------- +----------------------NDATETTDYLVPTGILRRADADVVTLASGPGPVRLFPAL----------------------TVEADATFDARNPAGADYVIVPAMSR-----DDDPAVLAWLREQARKGAIIIGVCAGAKVVAAA-------GLLDGKRATTHWYYLKELLG------------------RHSIRYVA-----DRRVVADHGVVTTTGITASMPMALLLIE---------- +-----------------------------------------------------------------------------------QILATHSFEN--PPPLDVLLIPGGILS--D-ENAPALNAFIAEQYPKLEYLLSVCTGARNLADA-------GVLEGKRATSNKAVWDTVIT-----------------HGKNVTWVP-----TARWVTDGNIWTSSGVAAGIDMMYAFLAHY-------- +-------------------------SALLDIACPADVLDAAAYDVTLASLDGRPIRCQNTLT----------------------LAAQDRLDRL-RGPVDTLIVAGGTGHAKA-AADVKLTTHVRRVAATARRVASVRTGTSVLAAA-------GLLNGRRATTHWMWAGMLG---RRYP--------------EVTIDP-----APLVIQDGNAHTAAGVTSGLDLTLSFVEA--------- +-------------------------------------------------------------------------------------------------AADTIIVPACADV--RQPAPAVLVEAIRRAHDRGTRIVGLCSGAFALAEA-------GILDGKRATTHWMYADALAS---QYP--------------GIEVDP-----AVLYTTDGNIFTSAGTAAAIDLCLELVRR--------- +-----------------------PGFSAMGFISALEPLRVANYRWQVLSLDGGAVQASNGM----------------------SVNADAALAADE--PGGILLIVAGFEPLA--CYGPALQQALRRLDHEGVVLGGIDTGAVVLAEA-------GLLDGHRATVHWEALEAFKE---RYP--------------RLQVT------QELFEIDRRRITCAGGTASIDLMLDLIGQA-------- +-----------------------PDFSLLNLSGFIQGLKIANFRWTIVSEHGNAVESSCGL----------------------TMPVGSDLPV-----QGLDYIVVNMGLDQ--QLSPKAKAWLHSAARHGSSFGALDGAVVALAKS-------GCLTCEPWSVHWHAFEAMRE---QFP--------------EMTFS------RRSFHHDTRVFSGAGATAGIDLALCEIQEL-------- +-----------------------PGFSALGFMSAIEPLRVANYRWHILSVDGAPVAASNGI----------------------SLNAEAAFADAD--DVQTVFVVAGFEPLA--CYSRALGDWLKRLDRANVTLGGIDTGAFILAEA-------GLLRPTSVTLHWEALSAFRE---RYP--------------SVEAS------GDLFEIGEGRITCAGGTASIDMMLDLIALS-------- +-----------------------PGFSALGFMSAIEPLRVANYRWHILSVDGAPVAASNGI----------------------SMNAEAAFGDVD--HARTVFIVAGFDPLA--CYSRALGDWLRRLDHAHATLGGIDTGAFILAEA-------GLLRATSVTLHWEALSAFRE---RYP--------------SVDAS------EELFEIGARRITCAGGTASIDMMLDLVSRS-------- +-----------------------PGFSAIGFMSAIEPLRVANYRWHILSVDGAPVSASNGI----------------------SLNAEAAFGDVH--HASTVFVVAGFEPLA--CYSRALADWLKRMDRAQATLGGIDTGAFILAEA-------GLVRATSVTLHWEALAAFRE---RYP--------------SMQAS------DELFEIGERRITCAGGTASIDMMLDLISRN-------- +-----------------------PGFSALGFMSAVEPLRVANYRWRILSLDGAPVAASSGI----------------------SINADAAIANVD--AAQTVFVVAGFEPLA--CYTRELGDCLKRLERGGATLGGIDTGSFVLAEA-------GLLSGASVTVHWEALSAFRE---RYA--------------SLNAS------QELFEIGARRITCAGGTASIDMMLDLIGRK-------- +-----------------------PGFSAIGFMSAVEPLRVANYRWRILSLDGAPVAASNGI----------------------SINADAAIGDVE--AARTLFVVAGFEPLA--CYTRELGDCLKRLARAGATLGGIDTGSFVLAEA-------GLLGGSSVTVHWEALSAFRE---RYP--------------SLDAS------QELFEIGARRITCAGGTASIDMMLDLIGRE-------- +-----------------------PGYSAIGFMSAVEPLRVANYRWRILSLDGAPVAASNGI----------------------SINADAAIGEAA--ITATLFVVAGFEPLA--CYTRELAEWLKRLERAGATLGGIDTGSFVLAEA-------GLLGGANVTVHWEALSAFRE---RYP--------------SLDAS------QELFEIGARRITCAGGTASIDMMLDLIGRK-------- +-----------------------DGVNPFELGVVCEVFGVDGYDFAVASADGPAVR---TIN-GF------------------SLQVAHGLER--LETADLIAVPAGAAYSREF--PPGMLDALRRGVDRGARVLSVCSGVFVLAAA-------GLLDGRRAAAHWKHAEELTR---QYP--------------HLTVEP-----DVLYVDEDPVITSAGTAAGIDACLHLVR---------- +-----------------------------------------------------------------------------------RLVTDLAFADVD-GSLDMLLVPGAVDLGPVARIDQEVVAWVKATAPQARRVASVCVGAHVVAAA-------GLLDGKTATTHWSTAAQLAA------------------DHAVRVDP-----DPIFVRSGNVWTGAGISACMDLALALVAED-------- +-----------------------EGFNELDSLIALGILNRPGWRVSIASPAAS-VR---SMN-G------------------VVLQAQASLKDA--CEADAVIVGSGAQT-RQVVADAALMAQL-KLDPARQLLGAQCSGTLVLAKL-------GLLQGVPACTDLTTK--------------PW-----AQEAGVEILN------QPFVARGNVATAGGCLASQYLAAWV------------ +-----------------------EGFNELDSLIALGILNRPGWRVSIASEATH-VR---SMN-G------------------VVLEAQASLRDA--SAADAVIVGSGMRT-RDVVRDEMLMEQL-RLDSRTQLLGAQCSGTLVLAKL-------GTLQGVSACTDLTTK--------------PW-----LEEAGIAVLN------QPFVAKGNVGTAGGCLASQYLAFWI------------ +-----------------------EGFNELDSIIALGTLNRPDWRVSIASPTAR-IT---SMN-G------------------LVIEAQASLDDA--RAADAVIVGSGVQT-REVVADARLMSQL-QFDPARQLLGAQCSGTLVLARL-------GLLDGVSACTDLMTK--------------PW-----LQEAGVNVLN------QPFFARGNIATTGGCLASHYLAAWI------------ +-----------------------EGFNELDSLIALGILNRPNWRVSIASPTSH-VR---SMN-G------------------VTLQAQATLADA--VHADAVLVGSGMQT-RHVVADPALMAQL-QLDPTRQLLGAQCSGALILAKL-------GLLNDVPACTDLTTK--------------PW-----VQEAGVQVLN------QPFVAHGNVATAGGCMASQYLAAWM------------ +-----------------------DGFNELDSFIALGILNRPDWHVSIASPSQQ-VR---SMN-C------------------VVIERQIDLIEA--SNADVVLVGSGMKT-RQIVEDKGIMSQL-SLDPSRQLIGAQCSGALILAKL-------GLLRNIPACTDLTTK--------------PW-----VQEAGVKVLN------QAFYANQGIATAGGCLASQYLAAWV------------ +-----------------------EGFNELDSLIALGILNRPGWRVSIASPAAQ-VR---SMN-G------------------VVLEAQASLRDA--SEADAVIVGSGMRT-LEVIDDATLMSQL-QLDPAGQLLGAQCSGALVLARL-------GLLDGVPACTDLTTK--------------PW-----VEQAGIDVLN------QPFFARDNVATAGGCLASQYLAFWL------------ +-----------------------DGFNELDSFIAAGILNRAGWNVQITSPSQY-VT---SMN-G------------------VTIQSQQPLEFA--NQANVVLFGSGVLT-RDIAQDRDILSRL-NLNPETQLIGGQCSGTLLVSVL-------GLLHQIPACTDLTTR--------------PW-----VVESGVTVLE------QPFYADGNLATAGGCLSSKYLAAWV------------ +--------------------------------------------MSIASDRAH-VR---SMK-G------------------LVVESHISLTEV--NHADAVVFGSGMKT-REIAEDHSIMSQF-KLDADKQLLVSQCSGTLLLSKL-------GLLKSKKACTDLTTK--------------PW-----VEEEGITVLN------QPFYAEGNVATSGGCLSSVYLAAWI------------ +-----------------------DGFNELDSFIAAGILNRFGWNVQITCPSEY-VS---SMN-G------------------VTIRAQQPLDFA--NKADAVLFGSGIFT-RKIAQDDQLLSQL-NLNPQRQLIGGQCSGTLLMSVL-------GLLDKVPACTDLTTK--------------PW-----VIESGVKVLE------QPFYAQGNIATAGGCLSSKYLATWV------------ +-----------------------EGFNELDSFIAAGILNRAGWHVQITCPAET-VT---SMN-G------------------VTVSAQQPLEFA--NTADVVLFGSGIYT-RDIADDPTILERL-RLNPEQQLIGAQCSGTLLLSVL-------GILKGLPACTDLTTK--------------PW-----VIESGIKVLN------QPFFAQGNVATAGGCMSSQYLAAWV------------ +-----------------------EGFNELDSFIASGILNREGWNVQITCPTET-VT---SMN-G------------------VTIQAQQPLEFA--NTADVVLVGSGMLT-RDIAKDPAILNRL-NLNPETQLIGAQCSGTLLLAAM-------DLLGSVPACTDLTTK--------------PW-----VQEAGVNVLD------QAFYAEGNLATAGGCLASQYLATWV------------ +-----------------------DGFNEMDSFMALTLLNRPGWRAELACPSMH-AL---SMN-G------------------VKITAQRPLMFA--SEADVVLFGSGAQT-RDHVKNDSIMSAF-HLDPELQLIGSQCSGALFLQSL-------GLLNNAPVCTDATTG--------------PL-----LQGLGVQVLE------GPFHASGNVATAGGCLSATYLAMWV------------ +-----------------------EGFNELDSLIALNILNRPGWQVAIASPTAK-VR---SMN-G------------------LVLEAQATLKDA--CEADAVLVGSGIQT-RAVAADAALMSQL-RFDPARQLLGAQCSGTLILAKL-------GLLNGVPACTDLTTK--------------PW-----VEEAGVAVLD------RPFAAKRNVATAGGCLAAQYLAAWF------------ +----------------------------MDSMIAFTMLNRLGLVAEIVSTHSN-VV---SMN-G------------------LRIQANPTLERL--EEYDGVIFGSSKLS-NQYAENSTFISSF-QLDPDRQYIGAQCSGVLLLIAK-------GIIGDVSISTDLKTE--------------SL-----VSATGLSFSS------SSFSSTSNIATAGGCLAAEYLASWM------------ +-----------------------EGFNELDSLVAYSILNRENWQVQITSPAPT-VT---SMN-G------------------LTISAHQPLAYA--NQADAVIIGSGSLT-RQIVADQSLMSAF-TLNPQKQLIATQCSGVLLLPAL-------GILDNAPVCTDLTTQ--------------PW-----AMDAGLVVLE------QPFHASQSVATAGGCLASQYLATWL------------ +-----------------------EGFNELDSFVASGIINRLGWNAQITSPTEQ-VT---SMN-G------------------VTIKAQQALEFA--NRADAVLFGSGVLT-RDIAKDTKILSRF-SLNPEKQLIGSQCSGALILAQL-------GLLDSVPACTDLTTT--------------PW-----LLDAGVKVLD------QPFFASGNIASAGGCLSSQYLATWV------------ +-----------------------QGFNELDSFIASGILNRAGWNVQITSPSET-VT---SMN-G------------------VSIAAQQPLEFA--NQADGVLFGSGSLT-REIAKDSAVLSRL-SLDPSKQLIGAQCSGTLLLSAL-------GLLDNTPACTDLTTK--------------PW-----VLEAGVEVLN------QPFYANRNLATAGGCLASQYLACWT------------ +-----------------------DGFNELDSFIASGILNRQGWKVQITCPTAT-VT---SMN-G------------------VTVMAQQQLEFA--NQADIVLFGSGIYT-RDIAADAAILQRL-KLDPQRQIIGAQCSGTLLLAKL-------GLLQGLPACTDLTTK--------------PW-----VIEAGVQVLD------QPLVANGNVATAGGCLASSYLAAWM------------ +-----------------------EGFNELDSFIAAGILNRDGWNVQITSPTAQ-VT---SMN-G------------------VTIDAQQPLEFA--NQADVVLFGSGILT-RDIASDEAILSRL-ALNPAKQLIGAQCSGALLLAKL-------GLLTNLPACTDLTTK--------------PW-----VIEAGVEVLN------QPFFAQGSIATAGGCLASQYLAAWA------------ +-----------------------DGFNELDSLIAYGMLSRKDWRVTIASPTPQ-VT---SMN-G------------------LTVDAHIDLVEA--CQADAVLVGSGRKT-REVAATPGIMEQLQ-FDPARQLLAAQCSGTFLLARL-------GLLGDAPACTDAISK--------------PW-----VVEAGVNVVN------QAFYANGNIATAGGCLASPYLAAWI------------ +-----------------------DGFNELDSFVASALFNRHGWQAAITCPSAE-VT---SMN-G------------------VRIHAQQPLEFA--READVVLFGSGIKT-REIATDAGILERL-QLDPQRQLIGAQCSGTLLMARL-------GLLQGMPACTDLTTK--------------PW-----VIDAGLEVLD------QPFFARGNLATAGGCLSAPYLAAWA------------ +-----------------------EGFNELDSFVATGLLNRQGWQAQITCPSEY-VT---SMN-G------------------VRVQAQQLLEFA--NEADVVLFGSGMQT-RAIAEDRGILERL-QLDPQRQLIGSQCSGTLLMAKL-------GLLGELPACTDLTTK--------------PW-----VIEAGTRVLD------QPFYAKGNLATAGGCLSAPYLAAWV------------ +-----------------------EGFNELDSFVAAGVLNRQGWLAEITAPTAS-VT---SMN-G------------------VRVQAQQPLEFA--NEADVVLFGSGILT-RDIARDSALLARL-RLDPARQLVGSQCSGALLMARL-------GLLGGIPACTDLTTK--------------PW-----VIEAGVEVLD------QPFFARGNLATAGGCLSAPYLAAWV------------ +-----------------------EGFNEIDSFVALNILNRPGWKAEIAAPTET-VT---SLN-G------------------VTIHAQRPLAFA--SEADAVLFGSGRLT-RQVAQDDGLMSQI-RVDPARQLVGSQCSGALLLKKL-------GLVEGLPLCTDATTR--------------PY-----LLETGATVLD------RSFYASGHIASAGGCLSAVYLAAWV------------ +-----------------------DQYNELDSLIALGILNRPDWKVSIASPSQD-VS---SMN-G------------------VVIQSTSSLEDV--NTADAVLIGSGMKT-REIASDKELMNKL-KLDPSRQLIGAQCSGTLILSKL-------GLLNNIPACTDVTTK--------------PW-----VVEAGVSVLN------QPFYAKDNIATAGGCLSSVYLAAWV------------ +-----------------------DCFNELDSFIASGILGRHGWTVRICAPAPI-VQ---SRS-G------------------ARVERQEDLSYA--ARADAVLIGSGWRT-RDWVDDDAIMSQL-RLDPSRQLIGSQCSGALVLHKL-------GLLSDGIACTDGMTR--------------PM-----LEQLGIAVAP------GAFRAVGNIATAGGCLASQYLAAWV------------ +-----------------------DGYNELDSLIAFGILNRPDWRVSIASPTAR-VT---SMN-G------------------VVLESHISLAQV--CEADAVIVGSGLKT-RDVVADETLMAQL-RLDPSRQLLAGQCSGTLILARL-------GLLQDIPACTDLITK--------------PW-----VQEAGISVLN------QPFFARGNVATAGGCLASQYLAFWL------------ +-----------------------EGFNELDSLIALGILNRPGWRVSIASPTAR-VR---SMN-G------------------VVIEAQASLREA--SEADVVIVGSGMQT-REVVADAGLMAQL-QLDPSRQLLGAQCSGALVLAKL-------GLLDGVTACTDLTTR--------------PW-----VQAAGVAVLN------QPFVANGNVATAGGCLASQYLAAWV------------ +-----------------------EGYNELDSLIALGILNRPGWRVSIASPTAR-VR---SMN-G------------------VVIESHVSLREA--SEADAVIIGSGMLT-REVVADPVLMKQL-QLDPSRQLLGAQCSGTLILAKL-------GLLKDVPACTDLTTK--------------PW-----VQEAGVDVLN------QAFFANGNIATAGGCLASQYLATWI------------ +-----------------------EGFNELDSMIALGILNRLDWRGSIASPTAR-VR---SMN-G------------------LVVEAQASLREA--SEADAVIVGSGRQT-RQVVADPALMAQL-QLDPSRQLLGAQCSGTLVLAKL-------GLGGGVPACTDLISK--------------PW-----VEEAGVCVLN------QPIVAKGNVATAGGCLASHYLAAWM------------ +-----------------------DGFNELDSLIAFGILNRPDWRVSIAGPAKQ-LR---SWN-G------------------LEIAAHVTLEEA--GHADAVLVGSGVKT-REVVADDAIMARL-RLDPSRQLLGAQCSGTLVLAKL-------GLLDTVPACTDLTTR--------------PW-----VQEAGVEVLN------QPFFADGNIATAGGCLASSYLAAWV------------ +-----------------------EGYNELDSLIALGVLNRTDWRVSIASPSPR-VR---SMN-G------------------VVIESHVSLDEA--SAADAVIVGSGRQT-REVVADQALMARL-RLDPSRQLLGAQCSGTLVLAKL-------GLLAGVPACTDSTSK--------------PW-----VQEAGVEVLD------QPFFAKDNVATAGGCLSSAYLAAWM------------ +-----------------------EGFNELDSLIALNVLNRPGWRVSIACPTAR-VK---SMN-G------------------LVIEAQASLQEA--CDADAVIVGSGVRT-RDVVADSELMAQL-QLDPSKQLLGAQCSGTLVLARL-------GLLDGVSACTDVTTK--------------PW-----VQEAGIDVLN------QPIFVSGNMATAGGCLASAYLAAWI------------ +-----------------------DGFNELDSLIALGVLNRPDWRVSIASPAKR-VQ---SMN-G------------------VVIEAHASLDEA--RHADAVIIGSGMQT-REIVANASIMAQL-QLDPSRQLLGAQCSGTLVLAKL-------GLLNGVPACTDLTTK--------------PW-----VQDAGIEVLN------QPFFSKGNVATAGGCLASLYLAAWV------------ +-----------------------DGFNELDSLIALGLLNRPGWEVSLCCPTAR-VC---SMN-G------------------VTVEAQSLLPYA--RSADAVLVGSGMKT-REVVQDTALMAQL-DFDPARQLLGAQCSGALILARL-------GLLDGVPSCTDLTTK--------------PW-----VQEAGITVLN------QPFVARGNVATAGGCLSAQYLAAWL------------ +-----------------------DGFNELDSLIALGILNRPGWEVALVCPQAR-VR---SMN-G------------------IVVEPHASLAWA--QGADAVLVGSGIQT-REVVENAALMGEM-QFDPSRQLLGAQCSGALVLAKL-------GLLDGVPACTDLTTK--------------PW-----VQAAGVTVLD------QPLFARGNVATAGGCLSSSYLAGWV------------ +-----------------------DGFNELDSFIASAILNRKGWAAHITSPTPE-VT---SLN-G------------------VTIQRQKPLAFA--HEADAVLIGSGIGT-RAIAADPAMLSQL-ALDPARQLVGAQCSGTLLLAKL-------GLIGDLPACTDLMSK--------------LW-----VIEAGVTVLD------APFIAHGNVATAGGCLASQYLAAWT------------ +-----------------------DGFNELDSFIAYGILNRPNWRVSIAGSSPQ-IT---SMN-G------------------LLVDRQIDLIEA--SKTDVVLVGSGMKT-RDVVLDQSIISQL-SLNPSRQLIGAQCSGALVLAKL-------GLLNEVPACTDLTTK--------------PW-----VQEAGVKVLN------QAFYANQNTATAGGCLSSTYLAAWV------------ +-----------------------DGFNELDSLIALGVLNRPGWRVSLAAPSET-VQ---SMN-G------------------VTLHATASLADA--CAAEAVIVGSGIRT-REIAADPAILSAL-QLDPARQLIGAQCSGTLLLAKL-------GILGDVPACTDLTTK--------------PW-----VQEAGVRVLD------QPFYAAGNVATAGGCLASPYLAAWI------------ +-----------------------DGYNELDSFIALGILNRPDWRISIAGPTPT-VR---SMN-G------------------VLVESMATLQEA--CAADAVIVGSGAKT-REVVEDPAIMSVLRGLDPSRQLLAAQCSGTLVLAKL-------GLLDGVPACTDNTTK--------------PW-----VVAAGVDVLN------RPFFANGNVATAGGCLASHYLATWL------------ +-----------------------EGFNELDSLIALGMLNCPGWRVSIASPTPR-VC---SMN-G------------------VVIDAQASLRCA--NGADAVLVGSGMRT-REVVADAALLAQL-RLDASRQLLGAQCSGTLVLAKL-------GLLDGVPACTDLTTK--------------PW-----VQEAGINVLN------RPFFANGNVATAGGCLASHYLAAWV------------ +-----------------------DGFNEIDSFVALSILNRNGLRAVITGPGPS-VT---SMN-G------------------VEVRIQEPLSFT--ATADVVLFGSGIHT-RDHINDPDLMAQI-QLDPSRQMIGAQCSGVLFLHKL-------GLLPA-TITTDTKTR--------------SL-----LVRTDT-VLED-----RPLVAQGNIVTSGGCLSSHYLAGWV------------ +-----------------------EGFNELDSFVALAILNRDGVHAEITGTGDS-VT---SMN-G------------------VSVSVQKPLSFA--QEADAVLLGSGIHS-RDHINDPDIMKQL-SLDPSRQLIGAQCSGVLFLYRM-------GLLPA-TVTTDTKTR--------------PL-----IARTEA-VIED-----RPLVAQGNIVTSGGCLSSSYLAGWF------------ +-----------------------PGFNELDSFLALHLLNRDDVTAFLAGPSPQ-AV---SMN-G------------------VVTGISGTLADA--ARADAVLVGSGRQT-REFASDPAFLASL-SLDPTRQLVASQCSGALILAKL-------GILTGLPVCTDNKTR--------------PW-----IEALELKVVQ------ETLLVTGNVATAGGCLSAQYLATWL------------ +-----------------------DGFNEIDSFVAAHILNRAGWKAEITAPTEF-AT---SLN-G------------------VKVAAQQPLEFI--HEADAVLFGSGRRT-AQVIEDAAIMSRI-KVDPQRQLIASQCSGALILARL-------GLLEGMPVCTDLKTK--------------PV-----AQAAGLRVLN------QPFYAQGNLASAGGCLSGQYLGTWM------------ +-----------------------DGFNELDSFIASAILNRHGWNVQITCPTDV-VT---SMN-G------------------VEVVAQQPLEFA--NQADAVLFGSGMLT-RQIATDRTILSRL-SLDPNRQIIGAQCSGTLLLAAL-------DLLNGVSACTDLTTK--------------PW-----VQDLGIEVLE------QPLHAHGNVATSGGCMSSQYLAAWV------------ +-----------------------DGYNELDSLIALGVLNR-GLRATIAAPTPT-VR---SMN-G------------------VVIESMATLDEA--GDADAVLVGSGIAT-REVVEDPTIMATLARLDPARQLVGAQCSGALVLARL-------GLLSGVPACTDLASK--------------PW-----VVAAGVEVLD------QPFYADGNVATAGGCLASQYLAGWV------------ +-----------------------DCFNELDSLIAAGILGRHGWNVRICSPAPI-VQ---SRS-G------------------TRVERQEDLSYA--NHADAVLIGSGWRT-RDWVADDSIMGQL-KLDPTRQLIGSQCSGALVLHRL-------GLLADGVACTDGITQ--------------PL-----LEQLGVRVQP------AAFRAAGNVATAGGCLSSQYLAAWV------------ +-----------------------EGYNELDSLIALGILNRPGWRVSIAGPTPR-VR---SMN-G------------------VTIDAMIDLDEA--CTADAVIVGSGSMT-REVVENPEIMNALRLLDPARQLLAGQCSGALVLAKL-------GLLADVPACTDLTTK--------------PW-----VIAAGVEVLN------QPFFARGNLATAGGCLASTYLATWV------------ +-----------------------DGFNELDSFVALALLNRAGWRAGICGPGET-VT---SMN-G------------------VRVDVQQEIEFA--GEADVVLIGSGVRT-REVVSDAKLMARL-RLDPARQIIGAQCSGALVLARL-------GLLEGVPVCTDVTSK--------------PW-----VVATGAQVIE------APFVAHGNVATAGGCMAAQYLSAWA------------ +-----------------------DGFNELDSFVALSLLNRHGWRATICAPNAT-VT---SMG-G------------------VTVTAGARLNEL--PDMDAIVVGSGVRT-RQIAADMELMARL-QLDAARQLIGAQCSGALLLAAL-------GLLGDGPVCTDVTTR--------------PW-----IEAGGASVID------APFHASANVATAGGCMAAYYLTAWM------------ +-----------------------DGFNEMDSFVALALLNRKGWRAMICGPGAT-VT---SMN-A------------------VQVAVQVDLDSL--AEMDIVLVGSGVRT-RQVAADGALMARL-RLDPARQLIGAQCSGALLLAGL-------GLLGDMPACTDLTSR--------------PW-----LVEAGAKVVD------APFHAAGNVASAGGCMAAQYLAAWA------------ +-----------------------DGFNELDSFVALALLNRPGWRAEICGPGES-VT---SMN-G------------------VRVDVQQPLEYA--GQADVVLVGSGVRT-LEMAADEALMARI-ALDPGRQIIGAQCSGALILARL-------GLIGDLPACTDVTSK--------------PW-----VIAAGVRVID------APFVAHGSVATAGGCMAAYYLSAWA------------ +-----------------------EGFNELDSLISLGILNRPGWRVSIACPSAR-VR---SMN-G------------------VVIEAQATLEDA--GAADAVIVGSGMQT-REVARNADLMSRL-RLDPSRQLIAAQCSGTLILAKL-------GLLNGVMACTDLTTR--------------PW-----VEEAGVRVLE------QPFFANGNVATAGGCLAAQYLAAWL------------ +-----------------------DGFNELDSLIALNILNRPGWRVSIASPTSH-VR---SMN-G------------------VALQAQASLEEA--KDAQAVLVGSGVRT-RDVVADAALMSRL-ELDPGRQLLGAQCSGTLILAKL-------GLLDGVPACTDSTTK--------------PW-----VEEAGVAVLD------RPFVANRNVATAGGCLSSQYLAAWV------------ +-----------------------DGFNDLDSLVAFGMLHRADWRVRIASPSRR-VT---SMN-G------------------LTIDAHEGLDTL--AGADAVLVGSGMKT-RDVAADPAIMEQLRVLDPARQLLAAQCSGTFLLGRL-------GLLGGVPACTDLTSR--------------PW-----VEASGVQVVQ------QPFVARGNIATAGGCLASQYLVAWL------------ +-----------------------EGFNELDSLVALGILNRPDWRVSIACPTPQ-VR---SMN-G------------------VVLQRQATLEEA--CRADAVLVGSGMQT-REVVADAALMAQL-QLDARRQLIGAQCSGTLVLAKL-------GLLAGVPACTDTITR--------------PW-----VEEAGVGVLN------QAFFAQGNVATSGGCLASQYLATWV------------ +-----------------------DGFNELDSLIALGVLNRPGWRVTLASPSAT-VT---SMN-G------------------VTVHASSTLEAA--AEAEAVLVGSGIRT-REVAADPAIMGVLRRLDAKRQLIGAQCSGTLLLAKL-------GLLGSVPACTDLTTK--------------PW-----VQEAGIEVLN------QPFFAQGNVATAGGCLSAPYLAAWL------------ +-----------------------DGFNELDSFIALGLLNRQGWKAQITSPTRH-VT---SMG-G------------------VTVEAQQPLEFA--NEADAVIFGSGLYT-RAIAEDGAALDRL-QLDPLRQLIGAQCSGTLLLARL-------GLLADVPACTDLTTK--------------PW-----VVEAGVRVLD------EPFHARGPIATAGGCLSSQYLAAWV------------ +-----------------------DGFNELDSFIALGLINRQGWSAAITSPSAQ-VT---SMN-G------------------VVVTAQQPLEFA--NEADVVLFGSGIHT-RAIANDSALLDRL-QLDPVRQLIGGQCSGTLLMARL-------GLLADMPACTDSTTK--------------PW-----VIEAGVRVVE------EPFHARGPIATAGGCLASQYLAAWV------------ +-----------------------DGFSELDTFVTFGLLNRAGWKAELVAPTAR-VT---SMN-G------------------VTVDTPQPLEFA--NEAAAVVFAGGLYT-RAIAENSAVIDRL-ALDPLRQLIGGQCSGTLLLARL-------GLLADVPAATDTASK--------------PW-----MIQAGVRVADD-----TPFHARGPVATAGGPLAAHYLATWL------------ +-----------------------DGFNELDSFIALGLMNRSGWTVDIAGPSQR-LT---SMN-G------------------VTIETQQPLEFA--NEADIVLFGSGIYT-RAIAENSALLDRL-QLDPLRQLIGAQCSGTLLLARL-------GLLADIPACTDLTTK--------------PW-----VVEAGVRVVD------APFHARGPIATAGGCMASQYLATWA------------ +-----------------------EGFNEIDSFVALSILNRDGWKAEITSPTPT-VT---SLN-G------------------ITIQAQRPLSFA--NEADVVLFGSGSKT-RQVVQDDKMLAIL-QLDPTRQLVGSQCSGSLVMKKL-------GLVENIPVCVDATTR--------------PF-----LLETGATVLDD-----RSFYAEGNVATAGGCLSSVYLAAWV------------ +-----------------------EGFNEIDSFVALNILNREGWKAEIVAPTET-VT---SLN-G------------------VTIQAQRPLSFI--NEADAVLFGSGRLT-RQIAQDVKLLSLI-KTDPQRQLIGSQCSGALLMNKL-------GLVEDMPVCTDATTR--------------PY-----LVEAGATVLD------QPFYADENIATAGGCLSSVYLAAWV------------ +-----------------------DGFNELDSLIAYGMLSRADWKVSISSPTAR-VT---SMN-G------------------LTIDAHIGLKEA--NQADAVLIGSGMKT-REVANDPSILGQLQ-LNPQRQLIAAQCSGTFLLAKL-------GLIGQTPACTDSSSK--------------PW-----VQAAGVKILN------QAFFADGNLATAGGCLSAQYISAWM------------ +-----------------------DGFNELDSLIAFGMLSRKAWRVSIASPTPR-VT---SMN-G------------------LTIDAHVDLVEA--CQADAVLAGSGRKT-REVAGDPAIMGQLR-LDPARQLLAAQCSGTFLLAKL-------GLLGQAPACTDTTSK--------------PW-----VQAAGVNIVN------QAFYANGNIATAGGCLSAQYLSAWL------------ +-----------------------DGFNELDSFIASALINRDGLEAFITTPTPV-VT---SMN-G------------------VEVTGQRPMEFI--PEADVVLIGSGVKT-RDVVADDRLLAML-PLDPARQLIGSQCSGALVLARL-------GLLGGMPACADLTSR--------------PY-----VEACGVTVLD------APFHAEGNIATAGGCLASQYLAAWV------------ +-----------------------DGFNELDSFIASALVNRDGLEAFITTPAPV-VT---SMN-G------------------VEVTGQRPMEFV--REAEVVLIGSGIRT-RDVIKDDRLLSML-PLDPSRQLIGSQCSGALVLARL-------GLLAGRPACADLTTR--------------PF-----VEEMGVTVLD------EPFHVEGNIATAGGCLASQYLGAWA------------ +-----------------------DGFNELDSFIASALINRDGLEAFITTPTPV-VT---SMN-G------------------VEVTGQRPMEFV--AEADVVLIGSGVKA-REVVADERLVSRL-VLDPSRQLIGAQCSGALVLAKL-------GLLGSMPACTDRVSR--------------PF-----VEACDVTVLD------APFHAEGNIATAGGCLASQYLATWV------------ +-----------------------DGFNELDSFIAAAMVNRDGLEAFITTPTPV-VT---SMN-G------------------VEVSGQRPLEFV--GEADVVLVGSGVRT-RDVVADARLVARL-PLDPGRQLIGAQCSGALVLARL-------GLLDGMPACTDTVSR--------------PF-----VEARGVTVLD------APFHAEGDIATAGGCMASQYLGAWV------------ +-----------------------EGFNELDSLIALGILNRPDWRVSLATPHAR-VK---SMN-G------------------VVIEGQIALHEA--NAADAVIVGSGVMT-RNVVADQTLMAQM-QFDPSRQLLGAQCSGTLILAKL-------GLLDGVPACTDLTTK--------------PW-----VEEAGVDVLN------QPFVARGNVATAGGCLASQYLAAWI------------ +-----------------------DGFNELDSLIALGILNRSDWRVSIASPSSR-IC---SMN-G------------------VVLEAHVPLTEA--AKADAVIVGSGSKT-REVVADAGVMAQL-RLDPSRQLIGAQCSGTLVLAKL-------GLLDGVSACTDLTTK--------------PW-----VVEAGVDVLN------QPFFANGNIATAGGCFASQYLATWI------------ +-----------------------EGFNELDSLIAFAILNRPDWRVSIASPVAR-VT---SMN-G------------------LVIDSHIDLQQA--CAADAVIVGSGMRT-REVVADEALMAQL-RLDPARQLLAAQCSGTLLLARL-------GLLDGVLACTDLTSK--------------PW-----VQEAGVQVLD------QPLFARGNVATAGGCLASTYLAAWV------------ +-----------------------DGFNELDSLIAFGILNRADWRVSIASPTQH-VR---SMN-G------------------ISVEAQVPLAEA--SNADAVLVGSGVRT-RDVVADPELMAQL-RLDPSRQLVGAQCSGTLILAKL-------GLLQPPPACTDLVTK--------------PW-----VEEAGVSVLN------QPFFAKGNLATAGGCLASQYLASWV------------ +-----------------------EGFNELDSLIAFGVLNRPGWRVSIASPAAR-VR---SMN-G------------------VVLEAQASLREA--STADAVIVGSGIRT-REIVADEALMAQM-QLDPSKQLLGAQCSGTLVLAKL-------GLLDGVPACTDLTTK--------------PW-----VQEAGVDVLN------QPFFARGNVATAGGCLASPYLAAWI------------ +-----------------------EGFNELDSLIAFSILNRPGWRVSLASPTKR-VR---SMN-G------------------LVLERQIPLAET--GDADAVLVGSGRQT-REVVADKGLMAQL-QLDPARQLVGAQCSGTLVLAEL-------GLLEDVPACTDLVTK--------------PW-----VEEAGVAVLN------QPFFARGNLATAGGCLASQYLASWV------------ +-----------------------EGFNELDSLVAFNILNRPGWRVSIAAPTAR-VR---SMN-G------------------VIVDRQTTLEEA--QGADAVLVGSGALT-RDVVADPALMDRL-RLDPTRQLVGAQCSGTLVLAKL-------GLLGGVPACTDLTTK--------------PW-----VQEAGVEVLE------QSFVARGNVATAGGCLASQYLATWV------------ +-----------------------DAFNELDSLVALSLLNRRDWRVSLACPTPI-VQ---SMN-G------------------VVLHAQASLADA--SAADVVLAGSGMNT-RKVVADTALMAQL-ELDPTRQLLGAQCSGTLIFAKL-------GLLDGVSACTDLTTR--------------PW-----VQEAGVAVLN------QPFFARENVATAGGCLASLYLASWV------------ +-----------------------EGFNELDSLIALGVLNREGWRVSIATPTAQ-VT---SMN-G------------------VSIGQMSTLEDA--VLADAVIVGSGIAT-REVVEDPTIMGVLRGLDPQRQLIAAQCSGALVLARL-------GLLHDVPACTDLTTK--------------PW-----VIAAGVDVLD------QPFFARGNVATAGGCLASHYLAAWL------------ +-----------------------EGYNELDSLIALGVLNRDDWRVTIAAPTAR-VT---SMN-G------------------VTIERMSSLDDA--VGADAVIIGSGIAT-REVVDTPAIMDVLRGLDPQRQLIAAQCSGALVLAKL-------GLLHDVPACTDLTTK--------------PW-----VIAAGVDVLN------QPFFAKGNIATAGGCLASHYLAAWL------------ +-----------------------EGYNELDSLIALGVLNRDDWRVTIATPGPK-VT---SMN-G------------------VVIEQMSTLEEA--CAADAVIVGSGIAT-REVVEDPAIMNVLRRLDPSRQLIAAQCSGALVLARL-------GLLGGIPACTDLTTR--------------PW-----VVAAGVEVLD------QPFYAKDNIATAGGCLASHYLAAWI------------ +-----------------------DAFNDLDSLVAFGMLSRADWQVRIASPTPR-VT---SMN-G------------------LTIDAHEDLSQL--AQADAVLVGSGMKT-REVANTPALMEQLRALNPDCQLLAAQCSGTFLLSRL-------GLLRGTPACTDLTSK--------------PW-----VVESGVDVVP------RAFTARGNVATAGGCLASQYLVAWL------------ +-----------------------QGFNELDSFVALGVLNRPDWRVTLCCPEPI-VT---SMN-G------------------VTVHAQSSLADA--VSADAVIVGSGMKT-REIADDPAIMSAL-RLDPARQLIGAQCSGTLVLAKL-------GILADIPACTDLTTK--------------PW-----VQEAGVTVLN------QPFYASGNIATAGGCFASQYLAAWI------------ +-----------------------QGFNELDSLIALGVLNRPGWRVTLSCPEPA-VT---SMN-G------------------VTVQAQSTLADA--CTADAVLIGSGMQT-RQVVNDAALMAQL-EFDPARQLIGAQCSGTLVLAKL-------GLLGNIPACTDLTTK--------------PW-----VLEAGVDVLD------QPFFARGNVATAGGCFASQYLAAWL------------ +-----------------------QGFNELDSFIALGVLNRPGWRVSLCCPETS-VT---SMN-G------------------VTVQAQSPLEDA--ASADAVLVGSGMLT-RQIVEDPALMGRL-RLDPRRQLVGAQCSGTLVLARL-------GLVDGIPACTDLLTK--------------PW-----VQEAGVQVLS------QPFFARGNIATAGGCLASAYLAAWV------------ +-----------------------QGFNELDSLIALGILNRPDWRVTVCSPEAE-VT---SMN-G------------------LTVRAQSVLEDA--ASADAVIVGSGVQT-REIANCPTLMSRL-SLRPEHQLIASQCSGTLILAKL-------GLLAGVPACTDLTTK--------------PW-----VQEAGVEVLN------QPFFANGNVATAGGCLASSYLAGWI------------ +-----------------------DGFNELDSLISLGVLNRPGWRVSLCCPQPT-VT---SMN-G------------------VVVQAQCLLSDA--RVADAVIVGSGIKT-REIVADPKIMSAL-QLDPERQLVGAQCSGTLVLAKL-------GLIGKVPACTDLTTK--------------PW-----VQEAGVEVLN------QPFFAAGNVATAGGCFASQYLSAWI------------ +-----------------------EGFNELDSLIALGILNRPDWKVSIACPSEE-VR---SMN-G------------------VVLKAQATLEDA--SRADAVIVGSGMLT-REVVADAALMARI-RLDPARQLLAAQCSGTLILAKL-------GLLADVPACTDLTTK--------------PW-----VEDAGVRTLD------QPFVAHGNVATAGGCLASQYLAAWV------------ +-----------------------DGFNELDSLIALGILNRPDWRVSIACPAPR-VR---SMN-G------------------VVMEAQADLRAV--SAADAVIVGSGIKT-REVVADAELMAQL-QLDPSRQLLGAQCSGTLVLAKL-------GLLGDVPACTDLTTK--------------PW-----VEEAGVRVLE------QPFVAHGNVATAGGCLASQYLAAWL------------ +-----------------------EGFNELDSLIALGILNRPGWRVSIASPAGK-VR---SMN-G------------------VVMEAQASLKDA--CDADAVLVGSGVRT-RDVVADATLMSQL-RFDTSRQLLGAQCSGTLMLAKL-------GLLDDVPACTDLTTK--------------PW-----VEEAGVAVLN------QPFVAKGNVATAGGCLSSQYLAAWF------------ +-----------------------QGFNELDSFIALGVLNRPGWRVTICCPEPR-VT---SMN-G------------------VTVEAQSTLEEA--ASADAVIVGSGMQT-REVVASDALMARI-RLDPARQLIAAQCSGTLVLARL-------GLVDGVPACTDLSTK--------------PW-----VQAAGVEVLD------QPFFARGNVATAGGCFASPYLAAWI------------ +-----------------------DGFNELDSLIALGILHRAGWRVSLCCPTPE-VT---SMN-G------------------VTVRAQSLLDEA--RTADAVIVGSGVRT-REVVEDAALMDRL-ALDPARQLIAAQCSGTLVLARL-------GLLGTVPACTDLTTK--------------PW-----VQAAGVNVLN------QPFYAEGNVATAGGCLASPYLAAWI------------ +-----------------------DGFNELDSLIALGILHRPGWRVSLCCPTPE-VT---SMN-G------------------VTVRAQSQLAEA--RTADAVIVGSGVRT-REVVEDAALMAQL-SLDPARQLIAAQCSGTLVLARL-------GLLGAVPACTDLTTR--------------PW-----VQAAGVNVLN------QPFYAEGNVATAGGCLASPYLAAWI------------ +-----------------------EGYNELDSLIALGILNRPGWRVSIASPSAK-VR---SMN-G------------------VVIEAQASLQDA--VAADAVIVGSGMQT-REVIADAALMQQLKPLDPTRQLLGAQCSGTLVLARL-------GLLDRVPACTDLITK--------------PW-----VQEAGVDVLN------QPFFAKGNIATAGGCLASAYLAAWV------------ +-----------------------DGFNELDSFIGAAILNRRGWQAHITAPSKQ-VT---SMN-G------------------VTVQRQRPLEFA--CEADAVLIGSGIRT-REIAEDTALLARL-QLDPTRQLIAAQCSGTLLLARL-------GLIGDLPACTDLTTK--------------PW-----VVEAGVNVID------APFAAHGNVATAGGCLAAPYLAAWI------------ +-----------------------DGFNELDSFVAAAIINRHGWAAHITAPTET-VT---SMN-G------------------VVVHRQRPLAFL--EEADAVLIGSGVRT-REIANDPAMLARL-RLDPARQLIAAQCSGTLLLARL-------GLIGDLPACTDLTTK--------------PW-----VVEAGVTVID------APFAAYGNVATAGGCLAAPYLAAWL------------ +-----------------------DGFNELDSFVAAGILNRRGWEAHIAAPTPE-VR---SMN-G------------------VVVQRQNPLEFA--READAVLIGSGIRT-REVAADPAMLARI-ALDPARQLIGAQCSGTLLLARL-------GLIGGLPACTDLTSK--------------PW-----VIEAGVEVID------APFVAHGNVATAGGCLASPYLAAWV------------ +-----------------------DGFNELDSFVAAAILNRKGWMAHITAPSET-VT---SMN-G------------------VTIHRQQPLEFA--AMADAVVIGSGIRT-REIANDPAMLARI-GLDPKRQLIAAQCSGTLLLAKL-------GLIGALPACTDLTTK--------------PW-----VIEAGVSVID------APFVAHDNVATAGGCLASNYLAAWL------------ +-----------------------DGFNELDSFIASAILNRKGWKAHIAAPTET-VT---SMN-G------------------VTVTRQKPLEFA--AEADAVVIGSGIHS-REVAGNPDLLARI-RLDPTRQFIAAQCSGTLLLAKL-------GLIGALPACTDLTTR--------------PW-----VIEAGIEVID------APFVAHGNVATAGGCLASHYLAAWL------------ +-----------------------DGFNELDSFIAAAILNRHGWKAHITAPTDE-VT---SMN-G------------------VVVRRQKPLGFA--AEADAVIIGSGVRT-REIAADPDLLDQI-RLDPARQLIAAQCSGTLILARL-------GLIDGVPACTDLTTK--------------PW-----VVEAGVNVVD------APFFAHGHVATAGGCLASQYLAAWM------------ +-----------------------DGFNELDSFVAAAILNRHGWAAHITSPDES-VT---SMN-G------------------VTVHRQRPITFV--EEADAVLIGSGIRT-REIAADAGLLARL-RLDPTRQLIAAQCSGTLLLAKL-------GLIGDLPACTDLTTK--------------PW-----VVEAGVTVID------APFAAHGNVATAGGCLAAPYLAAWM------------ +-----------------------EGYNELDSLIALGVLNRPGRRISIACPTDR-VR---SMN-G------------------VVIESMATLEEA--AAADAVIVGSGSRT-REVVEDGALMARL-RLDPTRQLLAGQCSGTLILAKL-------GLLDDIPACTDLTTR--------------PW-----VQAAGVDVLE------QPLFAKGDIATAGGCLAAHYLAAWL------------ +-----------------------EGFNELDSFIAAGILNRHGWTAHITSPTDS-VT---SMN-G------------------VTVKRQKPLEFA--AEADAVIIGSGIRS-REIATDNDLLSRI-SLDPSRQLIGAQCSGTLLLAKL-------GLIGDLPACTDLTTK--------------PW-----VIEAGVEVID------APFVAHGNVATAGGCMASQYLSAWI------------ +-----------------------EGFNELDSFIAAAILNRRGWAAYITAPTEW-VT---SGN-G------------------VTVQRQRPLEFA--AEADAVLIGSGWRT-REVAADPVMLARI-ALDPARQLIGAQCSGTLLLARL-------GLIGGLPACTDVTTK--------------PW-----VIEAGVEVID------APFVAHGNVATAGGCLASQYLAAWT------------ +-----------------------DGFNELDSFIAAGILNRQGWNAWITSPTEE-VT---SMN-G------------------VTVRRQRPIAFA--QEADAVLIGSGIAT-REIATDAALLAQL-ALDPARQLIGAQCSGTLLLAKL-------GLIGDLPACTDLTTK--------------PW-----VVEAGVDVID------APFVAHGNVATAGGCMASQYLAAWM------------ +-----------------------DGFNELDSFIASGILNRKGWKAHITSPTPQ-VT---SMN-G------------------VRITRQKPLEFT--AEADAVLIGSGIKT-REIAQDTDMLAKI-RLDPARQIIGAQCSGTLLLAKL-------GLIGSLPACTDLMTK--------------PW-----VIEAGVNVID------APFVAHGNVATAGGCLASQYLAAWM------------ +-----------------------DGFNELDSFVAAAILNRKGWAAHITSSTPA-VT---SMN-G------------------VTVQRQKPLEFA--SEADAVLIGSGLKT-RDIAANADLLARI-KLDPSNQLIGAQCSGTLLLAKL-------GLIGELPACTDLTTK--------------PW-----VIDAGVNVID------APFVAHGNVATAGGCLASQYLATWI------------ +-----------------------DGFNELDSFIAAGILNRKGWAAHVTSPTEQ-VI---SMN-G------------------VTVQRQRPLEFA--READAVLIGSGVRT-REIAADADLLARI-ALDPSRQLIGAQCSGTLLLARL-------GLVGDLPACTDLTTR--------------PW-----VVEAGVEVID------APLMAHGNVATAGGCLASQYLAAWM------------ +-----------------------DGFNELDSFIAAGILGRQGWEIAIASPTES-VT---SMN-G------------------AAIARQEPLDYA--AQADAVLIGSGIHT-RRIAEDADMLRQI-RLDPERQLIGAQCSGTLLLAKL-------GLIGKLPACTDLTTK--------------PW-----VEEAGVEVIE------APFVAHGNVATAGGCLASQYLAAWL------------ +-----------------------DGFNELDSFVAAGILNRQGWAAHITSPTPR-VT---SMN-G------------------VTIERQQPLDFA--TKADAVIIGSGIKT-REIAADPLMLGRI-RLDPARQLIGAQCSGTLLLAKL-------GLVGALPACTDLTTK--------------PW-----VIEAGVEVLD------APFVAHGNVATAGGCLASQYLAAWI------------ +-----------------------DGFNELDSFVAAAILNRRGWAAHITAPTAE-VT---SMN-G------------------VTIQRQRPLEFA--AEADAVIIGSGIKT-REIAADAAMLARI-ALDPTRQLIGAQCSGTLLLAKL-------GLVGGLPACTDLTTK--------------PW-----VIEAGVDVLD------APFVAHGNVATAGGCMASQYLATWM------------ +-----------------------DGYNELDSLIALGILNRDDLRISIASPTPR-VR---SMN-G------------------VVVEAMATLEDA--CTADAVIIGSGSKT-REIIDDAQVMATLRGLNPERQLIAAQCSGTLIAAKL-------GLLDGVLACTDDVTK--------------PW-----VIAAGVDIVN------KPFCVSGNVATAGGCLASQYLATWL------------ +-----------------------DGYNELDSLIALGILNRDDLRVSIACPTPK-VR---SMN-G------------------VVIEAMATLQDA--CAADAVIIGSGAKT-REIVEDPEIMTVLRGLDPRRQLIAAQCSGTLVAAKL-------GLLNGVPACTDDISK--------------PW-----VVTAGVDVVN------KPFCASGNVATAGGCLASHYLATWL------------ +-----------------------EGFNELDSFVAAGILNRAGWAAHITSPSAR-VT---SMN-G------------------VTVESQKPLEFA--EEADAVLIGSGMLT-RDIAADETLLSRI-RLDPSRQLIGAQCSGTLLLAKL-------GLVGDLPACTDLTTR--------------PW-----VIEAGVKVVD------RPFIAHGNVATAGGCLASQYLAAWM------------ +-----------------------DGFNELDSFVAAAILNRQGWAAHITAPNET-VT---SMN-G------------------VTVQRQRPLEFA--AEADAVLIGSGIRT-REIAADAAMLAQI-RLDPARQMIGAQCSGTLLLAKL-------GLIGDLPACTDLTTR--------------PW-----VVEAGVRVID------SPFVAHGNIATAGGCLSAPYLAGWM------------ +-----------------------DGFNELDSFIAAGILNRQGWAAHITCPTPE-VT---SMA-G------------------VTIQRQKPLEFL--ADADAVLIGSGIKT-RDYAADPTFLSRL-PLDPSRQLIGAQCSGTLLLAKL-------GLIGDLPACTDLTTK--------------PW-----VIEAGVNVVD------APFAAHGNVATAGGCLASQYLAAWM------------ +-----------------------DGFNELDSIIGLGILNRPGWRVSLASPSET-VT---SMN-G------------------VRLHRQASLDEI--DSFDAVLVGSGIRT-REIAEDASVMQILARLDAERQLIGAQCSGTLILAKL-------GLLNGVPGCTDLTTR--------------PW-----VQEAGIEVLE------QPFFARGNLATAGGCLASIYLAAWT------------ +-----------------------DGFNELDSLIALGLLNRPDWRVSLMAPTPL-VT---SMN-G------------------VRLERQAGFDEL--ADCTAVLVGSGNRT-RELARDAALLEQLAVLDPGRQLIGAQCSGTLLLARL-------GLLDGVPGCTDLTTK--------------PW-----VQEAGIEVLN------QPFFARGNLATAGGCLASSYLAAWA------------ +----------------------IEGVRKYKAAAAADILDRAGARVTVATASEGLVV---EAGHG------------------VRFAADGRVAGLEAEEFDLIVLPGGMKGSANLGDCKQLEKMVRKHTQSGRLCAAIGAAPAMVLAR------WGVLKGFTATCHPALLGRL----------------------GD---------D---DGDRTVVTSQGVGTAIEFALELVEQL-------- +------------------------------------------------------------------------------------------FDNLHPEGSDLVIVPAIHN-----AENKTIIHWIQNQYERGATIVGICDGVWTLGYA-------GLLKNKHATGHWYSKEKLSNV---F--------------SDTIWIR-----NKRYVQDKNIITTTGVTASIPVSLALVES--------- +-----------------------DGIIPFHLSVPCAVFELDLCEVTICATTPGQMKT---N-AG------------------FSIVVDKGLDAL--SGMDIVVVPSWNPA--VTHPDERLLTALRTAHQAGARIVGLCMGAFVLAAA-------GLLESRP---------------------------------------------------------------------------------- +-----------------------SGGPIFESSIPLSVFGIARYRLLVCAGEDVPLRT---T-GG------------------LELTAPYGLEAL--SRAGTVVVPAWRSI--TGPPPTAALDALRRAHEEGARIVGLCTGAFVLAAA-------GLLDG------------------------------------------------------------------------------------ +-----------------------DGMLHFELAATYEIFTA-DYDVKICGSGPV---R---A-GR------------------FTMEPDLPLDQL--ERADTVIVPAIEDV--DQPIDANLVRAVREAHRRGARIVSLCTG------------------------------------------------------------------------------------------------------- +-----------------------DHFSPFHCAVPCLIFGDPLFELRLCAGDATRPGS---A-QG------------------FRIDASHGLEGL--VGADIVIIPFWRDP--AERPAQPLLDALVAARNRGPR-------------------------------------------------------------------------------------------------------------- +-----------------------PNISPFHFSIPYMIFNI-LFDLKIISIENKKHET---Q-NV------------------MTIKSDGGLELL--EKADIIIIPGWHDL--TKPPKPSLANAIYQAYTRGAQIVGLCYGTYALAYT-------GIL-------------------------------------------------------------------------------------- +-----------------------DGVIPFEFSIPARLFGAALYEVVTASVDGGHVRT---N-SD------------------FMISPGMDLSAL--GSADTIVVPAVEVD--ELDPRQDVVIEALRRRRQGARIMSICTGAQLVLSS-------ARACGET---------------------------------------------------------------------------------- +-----------------------DGSNPFEMGVATEMFGLIWYDFELCAESPSVRMH---S-GF------------------FQLSGVAGLDAV--DRADTVIAPNRPDP--ETPPSPAVLDAVRRAAARGARLVSFCSGSFTLAAA-------GVLD------------------------------------------------------------------------------------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEDGPLRTTGGL----------------------ELTAPYGLDAL--GRAGTVVVPAWRSI-SQ-PPPAAALAALRRAHEEGARIIGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDILTSAGTAAGIDLCLHVVRTD-------- +------------------------GGPIFESSIPLSVFGDAGYRLLVCAGEEAPLRTTGGL----------------------ELTAPYGLEAL--ARAGTVVVPAWRSI-TS-PPPMEALQALRRAHEEGARIVGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------SVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHIVRTD-------- +---------------------------LSDFVVPYGVLSQSGAKVIAVNMTDGPLKGPLTVVPDM---------------------TAAAFDAAYPDGADYVLVPATGDA------YAEELVWLRAQYAHGAALVSICDGVELLAQI-------GVLDGRRATGHWASLRDRS---THYP--------------RVTWLE-----NQRYVADGTVASSAGVSASLPISLALVE---------- +------------------------GAPIFESSIPLSVFGDAGYRLLVCAGEEGPLTTTGGL----------------------TLTAPYGLEAL--SRAGTIVVPAWRSI-SQ-PPPVEAIAALRKAHHEGARIIGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------RVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHVVRSD-------- +-----------------------PGFSVMGFVSAVEPLRVALYRWHVLSADGGPVLASNGM----------------------SVNSDGALEPLK--KGDLLFVVAGFEPLR--AVTPALVQWLRKLDRNGVTLGGIDTGSVVLAEA-------GLLDGRRATLHWEAIDAFQE---SYP--------------QLSVT------QELFEIDGPRITSAGGTASIDLMLDLIAQAH------- +-----------------------PKFSMLTLFCMLEPLRVALFAWRLRSVDGEGVVASNGV----------------------CIEVDGRLADAP--DDAHLMVVSSYEAEA--TVMAQDRAVLRRIAAHGGWLGGLDTAPFILARA-------GVLEGHRVAMHWESVPAFRR---EFP--------------ALRIS------RRRFSSDATRQTGAGGTTGIDMMLDRIARDY------- +-----------------------PKFSMLSLFCLLEPLRVALFAWRLLSADGEGLVASNGV----------------------RIDVDGELDDVA--DAAHLMVVSSYEAEA--TIRGQDLAVLRRVAAHGGWLGGLDTAPFILARA-------GVLEGHRVAMHWESVPAFRR---EFP--------------HLRIS------PARFELDASRLTGSGGSASIDMMLAWMERLY------- +-----------------------PKFSMLTLFCLLEPLRVSLFAWRLLSSDGQAVVASNGV----------------------RIDVDGRLDDVD--QHAHLMVVSSYEPEV--TTTSRERSILRQVAAHGGWLGGLDTAPFILARA-------GVLEGHRIAMHWECIPAFRQ---EFP--------------NLTIS------DARYEFGHGRLTGSGGVASIDMMLTWVESSY------- +-----------------------PNFSMLTLFCLLEPLRVALFAWRLLSADGEAVVASNGV----------------------RIEVDGPLDAHC--HGELLMVISSYQPEV--SVTSAERAVLRHVAAHGGRVGGLDTAPFILARA-------GLLDHHRVALHWESVPAFRA---EFP--------------HIAVS------EARFEFAGQRLTGSGGAAGIDMMLQWIEHDY------- +-----------------------PKFSMLTLFCLLEPLRVALFAWRLLSADGQPVTASNGV----------------------YIDVDGAIGDLE--MITRLMVVSSWEAEA--TVTAEDRAVLRRLAAHGAWLGGMDTAPFILARA-------GVLDGVRVAMHWESLPAFRQ---EFP--------------SIRVS------TARFEWDSDRLTGAGGSASIDMMLMWIEQRY------- +-----------------------PKFSMLTLFCLLEPLRVALFAWRLLSADGEAVTASNGV----------------------RIDVDGRLSEVT--EKGRLMVVSSYEPEA--CIGAEDLALLKRLAAHGVWLGGVDTAPFILARA-------GVLEGYPVALHWESVPAFRE---EFP--------------ELEVR------ADSYVWEGGRLTGSGGAASIDMMLEWIVTLY------- +-----------------------PRFSMLTLFCLLEPLRVALFAWRLLSSDGEAVVASNGV----------------------RIDVDSALSSLV--NQTRLMVVSSYGPEV--SVGSQARGVIRHLAAHGAWLGGLDTAPFILARA-------GVLAGHRVALHWESVPAFRE---EFP--------------QLEIS------QADYEWQGERLTGSGGAASIDMMLAWIEFLY------- +-----------------------PRFSMLTLFCLLEPLRVALFAWRLLSAYGDAVVASNGV----------------------RIDVDGTLSSLE--DASRLMVVSSYEAEA--TVSSQDRAVLRRIAAHGGWLGGLDTAPFILARA-------GVLAGHRVALHWESVPAFRR---EFP--------------TLEIS------LTHYEFDAMRLTGSGGSGSIDMMLAWIEHAY------- +-----------------------QDFSMMSLASAIEPLRSYAFSWHLVSLNGEPVTAANGI----------------------SFPTCPVNQVLA--AGGERVVVVQYER--------GYQSAMRQAARAGLFIGSLSTGTFLLAKC-------GRLNGHRCTIHWESRAAFAE---SYP--------------DIECT------RKIYEIDRHRLTCSGGTAAMDMMLNLIAERY------- +-----------------------AGFQAMDIFGPLDALNSHTMTLSLISADLGPVM---TLNPDAVT---------ASPAFTQSVLPTHTLVEA--PVVDILIVPGGLGNRDPIA-MAPYVDFIRERWAELRHVLSVCTGAALVART-------GCVDGMRATTNKKVFKWVRG-----------------QRKEVDWVG-----HARWVEDGKWWSSSGISAGTDMMLGYIE---------- +-----------------------PNFSMIAFATAIEPLRIAGYQWRLTSVDGKPVTASNGVE----------------------CAVNASLEDEREQRPSMVFVCSGVH-VEEF-RNKSVFAWLREEYNRGVAVGGLCTGAHILAAA-------GLLSGRRCAIHWENLPGFSE---AFP--------------KAEVY------ADLFEVDSNLYTCAGGTASLDMMLKLIGDD-------- +-----------------------PNFSMLPFSAAIETLRIAGYTWRLTSTDGEKVLSSSGIA----------------------LEVNSSLADEGENRPSMVLVCSGIY-VEDF-NNKSVNAWLREVYNRGVAVGSLCTGAHVLASA-------GLLTGKRCAIHWENLPGFSE---NFP--------------QVDVY------ADLYEIDSNIYTCAGGTASLDMMLNLIDQD-------- +-----------------------PNFTMIAFTNAIEVLRMANYRWSIISPQGGMVTASNG------------------------LAVDTGPAEC-AGQPDIVFVCGGVDV-QR-ATQPEHLAALRRFARAGVALGSLCTGTYALAKA-------GLLAGYACAIHWENLSALKE---EFP--------------DTRFL------KELFVIDRDRVTCTGGVAPLDMMLNLIA---------- +-----------------------PNFTMIAFTNAIEVLRMANYRWSVISPDGGPVTASNG------------------------LTVDTGPAEC-AGQPDIVFVCGGVDV-QR-ATTPAHLSTLRRFARSGIPLGSLCTGTYALAKS-------GLLAGYACAIHWENMSALKE---EFP--------------DTRFL------KELFVIDRDRITCTGGVAPLDMMLNLIA---------- +-----------------------NGTEEMELITIVDVLRRAEAADVVVASAEDAAE--VVARHG------------------MRIVADTTLDEAAQTSFDLIILPGGTPGAKTMSSNEKLVALLKKQAAASKPYGAIGAATAHVLEP------HGLLEGKKAADG----------------------------AGEGEGE-----GSRVVVDGNVITGSSAGTAMEFAVAAVEKL-------- +-----------------------NGTEEMELITIIDVLRRADADVVVASAENAGVE--IVARHG------------------MRIVADTTLDEAATSSFDLIILPGGTPGAKTMSSNEKLVTLLKKQAAASKPYGAIGAATAHVLEP------HGLLEGKKAADQ----------------------------DGGD-EC-----ESRVVVDGNVITSGGTGTAMEFAVAAVEKL-------- +-----------------------NGSDEMEVLVTVDVLRRANADVVVASAGGDEVV--VVARHG------------------TRIVADALLVDAVGQQFDFVVVPGGMAGAKTLAGTEALVALLKEHAAAGRAYGAIGAATAEVLEP------HGLLELEGK-SM----------------------------A-DSREC-----GSRVVVDGNLATSSGPGTAMEFALAVVEKL-------- +-----------------------NGSEEMEVLVTVDVLRRAKADVVVASA---EEV--VVARHG------------------TRIVADALLQDAAGQQFDLIVVPGGMPGVKTLADKVELMALLKEHAAAGRAYGAIGAATAQVLEP------HGLIGG--S-SR----------------------------ADRPSEC-----GSRVVVDGNLATSGSTGTAMEFALAVVEKL-------- +-----------------------NGTEEMELITIIDVLRRAEANVVVASADDAGVE--IVARHG------------------MRIVADTTLDEAAQMSFDMIILPGGTPCAKTIGSNEKLVTLLKKQAEACKPYGAIGEATAHVLEP------HGLLERECKAKD----------------------------GSAGECE-----MSRVVVDGNVITSRSAGTAMEFAVAVVEKL-------- +-----------------------DGVRALDLAGPTEVFEIAGYTTGLYSTANSPVRCASGM----------------------TVHATA-ASE--LTNADTLLVPGGDDPARS--AAPWLSKVLRAQLNDVRRIAALGTGCFALAAA-------GILDGRRTTTHWRHLDAFAAR---HP--------------TAVLDR-----ESAFTRDGPVWTSAGASAGVDLALALVGED-------- +------------------------GAPIFESSIPLSVFGDAGYRLLVCAGEDGPLATTGGL----------------------TLTAPYGLETL--ARAGTIVVPAWRSI-S-QPPPPEAIAALRKAHHEGARIIGLCTGAFVLAAA-------GLLDGRPATTHWMYAPTLAK---RYP--------------KVHVDP-----RELFVDDGDVLTSAGTAAGIDLCLHVVRSD-------- +-----------------------DGVHPFELGVACEVFGLEGYDFAVASAEGPTLRTPS----GF------------------TVSTTYGLDR--LEEADLVVVPAGDSYVHR-IYPTELLDALRRAVDRGARVLSVCSGVFALGAA-------GLLDGRACAVHWKHAEELAR---RYP--------------RAIVEP-----DVLYVDADPVITSAGTAAGIDACLHIVRKE-------- +-----------------------PNFTLTAFSGFVDMLRLSADDWTVIGDTLAPVRASC----------------------GIQLTPWQTFDA--ADAFDYVVVVGGLLH-SGPQAGPQTLEFIRRAAAAGANLVGICTGAFALMRA-------GVLDGHRVCVSWFHYWDFVE---RFPGAD-----------PDLLIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PNFTLTAFSGFVDMLRLASDEWQVVGESLAPIRASC----------------------GARMSAWSTFDD--AEDFDYVVVVGGLLR-SGNEASPATLAYLRRMADTGSTMVGVCTGTFALMRA-------GLMENHRTCVSWFHYWDFLE---QFPQFD-----------PDYLVA-----DRLFVIDRRRITCSGGRSSIDVAASILGRH-------- +-----------------------PNFTLTAFSGFVDMLRLSADDWSVIGETLAPVRASC----------------------GIQITPWETFDE--AQPFDYVVVVGGLLH-SGPQAGPETLDFIRRTAADGATVVGICTGVFTLMRA-------GVLEGHRTCVSWFHYWDFIE---RFPAAD-----------PDLLIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PNFTLTAFSGFVDMLRLSADDWSVIGDTLAPVRASC----------------------GIQITPWETFDT--AEPFDYVVVVGGLLH-SGPQAGPETLDFVRRAAAGGATIVGICTGVFALMRA-------GVLDAHRICVSWFHYWDFIE---RFPSVD-----------PDLLIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PNFTLTAFSGFVDMLRLSADEWSVIGDTLAPVRASC----------------------GIQITPWETFAD--AEPFDYVVVVGGLLH-SGPQANDETLQFIRAAARGSTTLVGICTGVFALMRA-------GVLDEHRICVSWFHYWDFVE---RFPSVN-----------SDALIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-------------------------------------MQSGRDDWTVVGETLLPVRASC----------------------GIQIQPWQTFDE--AGTFDYVVVIGGLLH-SGPGVSDTTLRFIRRAAETSSTLVGICTGVFALSRA-------GVMDGHRVCVSWFHYWDYIA---RFPEVD-----------ERLLVA-----DRLFVIDRRRISCSGGRASVDVAAAILQLH-------- +-----------------------PNFTLTAFSGFVDLLRLASDEWTIVGESLVPVRASC----------------------GIQVAPWTTFDE--AGEFDYVVVVGGLLH-SGPSASRATLQFIQHAATTPATLVGICTGVFALMRA-------DVMDGYRICVSWFHYWDFVE---RFPGVD-----------ERNLVA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PNFTLTAFSGFVDLLRLASDDWTIVGETLTPVRASC----------------------GIQVQPWQTFDE--AGRFDYVVVIGGLLH-SGPGVSDATLRFIRGAADASSTLVGICTGVFALSTA-------GVMDGHRVCVSWFHYWDYIE---RFPHVD-----------ESLLVA-----DRLFAIDGRRITCSGGRASIDVAAAILQRH-------- +-----------------------PHFTLTAFSGMLDVLRLAGDEWQVVDETLAPVRSSS----------------------GIQVVPSEVLGD--PARFDYVVVVGGLLQ-R-PPVSAGMLEFIREAACKDVRLVGLCTGVFTLMQA-------GVLDQHRICVSWFHYWDFLE---HFPCVD-----------PAQVIA-----DRLYVFDRRRITCSGGRASIDVAAEILRRH-------- +-----------------------PNFTLTAFSGFVDMLRLSADDWTVIGDTLAPVRASC----------------------GIQITPWQTFDE--AEPFDYVVVVGGLLH-SGPQAGPETLRFIRDAAAAGANMVGICTGVFALMRA-------GVLDAHRICVSWFHYWDFIE---RFPNVD-----------PQRLIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PHFTLTAFSGLLDILRLAGDEWHVIDETLAPVSSSS----------------------AIQVVPSEKLGD--PSRFDYLVVVGGLLH-TGLPLSAAQKRFIQQAADSNVNLVGVCTGVFALMQA-------GVMQDHRICVSWFHYWDFIE---QFPHAD-----------PNLIVA-----DRLYVCDRRRITCSGGRASIDVAADILKRH-------- +-----------------------PNFTLTAFSGFVDMLRLSADDWSVIGETLSPVRASC----------------------GIQVTPWETFEE--AEPFDYVVVVGGLLH-SGPQASPKTLEFIRHVAGAGATLVGICTGVFSLMRA-------GVLDGHRTCVSWFHYWDFID---RFPSAD-----------PDLLIA-----DRLFVIDRRRITCSGGRASIDVAAAILLRH-------- +-----------------------PHFTLTAFSGLLDVLRLAGDEWQVIDETLALVRSSS----------------------GIQVVPSETLGD--AGRFDYLIVVGGLLH-TGLSLSTAQKAFIRQAAARNVNLVGVCTGVFALMQA-------GVMEGHRLCVSWFHYWDFIE---QFPQAD-----------PDLIVA-----DRVYVSDRGRITCSGGRASIDVAADILKRH-------- +-----------------------------------------------------------------------------------KITADRTIAN--TKDLEVLVIAGGEIEPINIAKDKKVIDWIKAIDKKTIYTTSVCNGAWILGAT-------GLLKGKNATGHWYQADEL----------------------------------------------------------------------- +------------------------------------------------------------------------------------LAATDSFETC--PPLDIVLIGASFQP----GITEAELAFVRKSYQECSAFITVCGGIEAPLRA-------GILEGKTATAPRFMLEELRL-----------------KAAGTQWVE------RRWARDGKLWTSGTLLNGLDLMSAFIRA--------- +-------------------------------------------------------------------------------------------------------MGAHNVGY---QPNEVELAYVRKAYENSSAFITVCGGIQAALDA-------GVLKGKSATCPRFLLPYARK-----------------TAPDTKWEE------KRWQRDGKLWTSGALLNGLDLIRAFGKE--------- +-------------------------------------------------------------------------------------------------------MGAHNVNY---KPNEKKLAYVRKAYEEATVFVTICGGIQSALEA-------RVLKGKSAIAPRVLLPMAQQ-----------------LSPDTEWYE------KRWHRDGKLWTSGALLNEVDLRYAFVNE--------- +-------------------------------------------------------------------------------------------ENC--PQLDIVLMGAHMIGY---EPNQTELAFVRKAYEECSAFLTICGGVMVPLQA-------GILDGKTATAPRLMLPNLYK-----------------QVPGTKWVD------RRYANDGKLWTSGALLNGLDLMSAFAKA--------- +------------------------------------------------------------------------------------MNPTDTFDTC--PPLDIVLMGAHHPSY---TPSAVELAYIRKAYDASAAFLTICGGLMAPLQA-------GILDGKTVTAPRFMLGQLRE-----------------TNPGSTWLE------KRWVRDGKLWTSGALLNGADMVSAFVRE--------- +----------------------------------------------------------------------------------------HSLSNA--PPLDILIIPGSAPII---TARPAIDAFIQSAAAHGTTILCICTGIFPTAAS-------GVLEGRAATGPLVMLSTLRA-----------------QHPEIQWNN------TRWEGSGDIWTSGSIANGVDLMCAFMRE--------- +-----------------------DNVLTTELTAPMDVFTKLGFNVITIAETYDFIVSEE----------------------GLKMFPDYILENS--PKLDVLIVPSAYD-MSLQVKNQNLVDFIKAQNNNTEYTVSNCAGATLIGES-------GIADGKKIVTWIGGGEDLQK---NYP--------------NLKVQDD---GNVSYMEDGKFLSSNGNLASYISSLEL------------ +-----------------------NGVLTTEVTAPLDVFTKPGFNVITIAENKNIIISEE----------------------GLKIQPDYTFENA--PKLNVIFVPSAYD-VSSQVKNKNTIAFIKTQNENTNFTVSNCAGAQLIGES-------GIANGKKIVTWIGGGKELQK---NYP--------------NLIVQND---SLVSYIEDGKFLSSNGNLASYISSLEL------------ +-----------------------DRVLMTEVTAPMDVFSKHGFNVITIAETLDPVETEE----------------------GLVVVPDFTFDTA--PKLDVLFVPSAYD-MWTAVRNEKLVNFIIEKNKETTYTVSNCGGAQLIGKS-------GIASGKKIVTWIGGGEQLQK---DYP--------------DLLVQND---AEVSFVTDGKFYSSNGNLASYISSLEL------------ +-----------------------NGVLQSEVIATSDVFAKPGFNVITIAETEKPITTEE----------------------GIKILPDFTFENC--PKLTALFVPSAYD-MYAQVHNEKIVNFIKEKNKETEYVVSNCAGAQLIGKS-------GIADGHKIVTWIGGGEQLQK---DYP--------------NLKVQND---SLVTFVEDGKFSSSNGNLASYISALNL------------ +-----------------------NGVLQGEVIATSDVFGKPLFNVITIAETKKPITTEE----------------------GMHFVPDYTFDNC--PKLTALFVPSGYD-MYAQVRNKKMVDFIKKKNNETKYIVSNCAGAQLIGKS-------GIADGHKIVTYIGGGKQLQK---EYP--------------NLKVQND---SLVTFVEDGKFSSSNGNLTSYISALRL------------ +-----------------------NGVLQSEVIATSDVFAKPEFNVITIAETENPIITEE----------------------GIKIVPDYTFENC--PELEALFVPSAYD-MYAQVHNDNIINFIREKNKETKYTVSNCAGAQLIGKS-------GIADGHKIVTWIGGGEELQK---TYP--------------ELKVQND---SLVTYVKDGKFLSSNGNLASYISALNL------------ +-----------------------NGVLQSEVIATSDVFSKPGFNVITIAETENPITTEE----------------------GIRILPDYTFENC--PKLEALFVPSAYD-MYAQVHNEKIVNFIKEKNKETKYTVSNCAGAQLIGEA-------GIARGHKIVTWIGGGEQLQK---DYP--------------ELKVQND---SLVTYIKDGKFLSSNGNLASYISALNL------------ +-----------------------DGVLQSEVIAASDVFAKAGFNVITIAENMEPVITEE----------------------GMRFLPDYTFENC--PHLTALFVPSAYD-MYAQVHNEEIINFIQSKHQETDYIVSNCAGAQLIGKS-------GIAQGTKIVTWIGGGEQLQK---DYP--------------DLKVQND---SLITFVRDGKFLSSNGNLASYISSLEL------------ +-----------------------NGVLQSEIIATSDVFAKPGFNVVSIAETKSPITTEE----------------------GMHFVPDYTFDDC--PKLTALFVPSAYD-MYAQVHNEKIVNFIKEKNKETEYVVSNCAGAQLIGKS-------GIADGFKIVTWIGGGEQLQK---DYP--------------NLKVQDE---NLVTFVEDGKFSSSNGNLASYISALKL------------ +-----------------------NGVLTTEVTATADVFTKHGFNVITIAETADPIISEE----------------------GLKITPDYTFENC--PKLDVLFVPSAYD-MYTQVHNPKIVDFIKEQNKNTKYTVSNCAGAQLIGAS-------GIADGKKIVTWIGGGEQLQK---DYP--------------NLKVQDD---KVVRYMEDGKFISSNGNLISYVSALNL------------ +-----------------------NGVLQSEVVATSDVFAKPGFNVITIAETDNPITTEE----------------------GMHFVPDYTFDNC--PKLTALFVPSAYD-MYAQVHNNKIIDFIREKNEETKYTVSNCAGAQLIGAS-------GIADGKKIVTWIGGGTQLQK---DYP--------------NLKVQND---SLVTFVRDGKFLSSNGNLASYISALNL------------ +-----------------------NGVLQSEVIATSDVFAKPGFNVISIAETESQITTEE----------------------GMHFVPDYTFENC--PKLTALFVPSAYD-MYAQVHNEKIVNFIKEKNKETEYVVSNCAGAQLIGKS-------GIADGHKIVTWIGGGKDLQK---EYP--------------NLKVQDD---SLVTFVEDGKFSSSNGNLASYISALNL------------ +----------------------------------------------------------------------------------------ASFEAI--ASCDAIIVPSFWPDPPDMSRFGVAAAWLRRHHARGALIAGCGSGAFLLGEA-------GLLDGRRCTTSWRHHEELK-------------------QRYARID---AAWGARLIEDRRVVTAAGPLSWIDVALHVVRA--------- +-----------------------EGTEMFDLMAPFYLFNATGANVYVVSEEKAPVLLVNSL----------------------FILPHYSFREIDSIQPDVIVVPNLTVHLKS-PPRPSTVAWVRKQYTGKNILLAICDGAATAAAT-------GLYDGLPITTHSSDWGKLEK---LYP--------------RGDWKK-----GLSYTRSGNLYSTAGVSNATEGSLAV------------ +----------------------ADGTEDIEFVTLVDVLRRAGVSVVVGSVSESLN---LVMAH------------------GTKIVADDKVANLTQKVFDLIAVPGGLVGATNFYNSAALISMLKDQKQSGRLYAAICASPALLGDA-------GLLDDHGAVCFPGFEHKL----------------------------------------------------------------------- +-----------------------NGSEEMEAITIVDALRRANADVIVASVEDGFDV-----TAR----------------YGTRIVADVMLDEADRAPFDLIIVPGGLPGAKTLGRCEQLVTLLKKHAEANKPYGAIGAATAHVLEP------HGLLKD------------------------------------------------------------------------------------ +------------------------------------------------------------------------------------------------ASADVIIVPSWRDP-DETP-PDALLEALRAAHARGAQVVGLCLGSYVLAAA-------GLLDGRAATTHWAWADDFMR---RYP--------------RVRLDP-----NVLYIDDGNITTSAGTAAGLNCCLHVLRR--------- +--MKKVLCLIY------------PNFSLYEVVGLTSTLGSFGVEVDYAGSDRNVIRSEDGL----------------------ACQPTRTLDEVVIEDYSCVILPGMINIVPA-LHDEKLISFLKSLKQQEILIAAISSAPILLARA-------GLLNDTKFTGG------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------TITPTYDLKEDEAKRYDLLVFGALSSSRTEYGHTQTTKDYLKAHNRQGKDVMTVCIGVQVVAEL-------GLLDGKNATTNSLFLDDFRN---GFP--------------NVRWLSADASSKNRVVQSEAITTCAGVSSGIDGALAQAKK--------- +-----------------------NGSEEMEIIMLVDILRRANINVVLASVDESTN-----IV-----GSQ-----------RMKIVSDKCILGASDSKYDLIIIPGGPEGAELLHRSTALKKLLKEQKQASRMYGGICYSPLILQKQ------------------------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------------------------------------------AIDFIRARFPELKYMITVCTGSRLAARS-------GVLDGLRATTNKRAWLDTRE-----------------MAPAVKWVA-----HARWVVDGKCWTSAGVSAGIDVVLAWMEKV-------- +-----------------------------------------------------------------------------------------------------------------------VQDYLTAVAPYVHSIVTVCTGSHVLSQT-------GLVDGLQLTTNSARYDDVIK-----------------HTADVNWQC-----NRRWLREIDIWSSAGITAGIDVMLEFISAH-------- +------------------------------------------------------------------------------------------------------------------------------AHRSGTVLAGVCTGVLVLSAA-------GLLKGRPCTTHHLAKDAL-------------------AQEGGDVL------SSRVVDDKDIVTAGGVTSGLDLALWMVTR--------- +-----------------------PGFSAIGFISALEPLRVAGYRWHVLSADGGAVQSSNGM----------------------SVNADAALESLK-KGATLLVVA-GFEP-LQF-ATPALQHWLRRLDHEGVTLGAIDTGACVLAET-------GLLDGHRLTLHWEAIEAFKE---SYP--------------QLTVT------QELFEIDRRRITCAGGTASIDLMLDLIAQ--------- +--MKKVAVILSGC-GVF------DGAEIHESVLALHAIEKQGASWHCFAPNVQQMH---VINH--LTGEEMP--ETRNVVESARIAKIQDVATLNVNEFDALLLPGGFGAAKX---------------------------------------------------------------------------------------------------------------------------------- +--MKKIGVILSGC-GVY------DGSEIHEAVLTLLAISRSGAQAVCFAPDKQQVD---VINH--LTGEAMT--ETRNVIEAARITEIRPLAQADAAELDALIVPGGGWRGEE---------------------------------------------------------------------------------------------------------------------------------- +--MKKVAVILSGS-GVF------DGAEIHEAVLALHAIEKQGASWHCFAPNIDQLH---VINH--KTGEEMD--ETRNVVEAARIANIEDVAKLNVDDFDALLLPGGFGAAKN---------------------------------------------------------------------------------------------------------------------------------- +---RKVAVILSGC-GVY------DGAEVHESVLTLLGIEQQGATYQCFAPDMNQHH---VINH--LTGEDTG--EQRNVVEAARIADIEPLAALKVADFDALIVPGGFGAAKN---------------------------------------------------------------------------------------------------------------------------------- +--QKKVAVILSGC-GVY------DGAEIHESVLTLLRLDQRGAQVQCFAPDIAQHH---VINH--LTGEEMP--ESRNVIESARIAEVKDIREANADDFDALIIPGGFGSAKN---------------------------------------------------------------------------------------------------------------------------------- +--KITSLQILCGC-GYL------DGTEISEAVSATIHVAQKDMKPCFYAPDQEICN---IIDH--CSRKLDPDSSPRNAVEAARLASIKPLCECEACTHGALVIPGGFGAAKI---------------------------------------------------------------------------------------------------------------------------------- +--------ILCGC-GRL------DGTEISEAVSTAIHLRHKNMKPLFYAPDMEING---VVNH--LTREMDTT-TPRNAVEGARLACIKPLCECEACTHGALIIPGGFGAART---------------------------------------------------------------------------------------------------------------------------------- +-----------------------------------------------------------------------------------AIVPTMTFEQC-PEELDEFFVPGGPKGILTALQNDGLLDFVSHRGSRARYITSVCTGSVLLGAA-------GLLEGYKAASYWGTLDIL----------------------------------------------------------------------- +-----------------------NGTEEMELITIIDVLRRADADVVVASAENAGVE----------------------------IVAR-----------HGMRI-GGTPGAKTMSSNEKLVALLKKQAAASKPYGAIGAATAHVLEP------HGLLEGKKAAD---------------------------QDGGGEC-------ESRVVVDGNVITSGGTGTAMEFAVAAVEK--------- +-----------------------PDLTALDALGPFEVFARADTRVLLVSSAPSPPP---SAPPSPVTS-----------DAGLLLPHVPSLALC--PPLHVLLVPGGPGQ-VAMMEDEHVLAWIEHQARTCMYVTSVCTGSLVLAAVGKREKGGGLLDGVRATTHWMFLDQLRQMGVE-----------AVK--GERVVRTTTCWEGGKTRDVVIYTGGGVTAGIDFAFAVKHCM-------- +-----------------------MGSEEIEVAALCDILARGGVRVTVANVGGSLHH---IIK--LAK--------------GTGVQADKPLEFCVNEEYDVIAVPGGPGA-KTLGACRMLTTLLKKQKTAKKLYAAVGEATYEVLFHN------ALVEG-PMAGDPADKLIM----------------------SDLYF------DDDVVITENCVTSKGPATVIAMADDEKRR--------- +-----------------------VGSEEIEVAALCALLARGGVRVTVANVGGYLHH---IVK--LAK--------------GTDIQADKPIDFCVNEDYDVIAVPGGPGA-RTLGACQALTALLREQKAAGRLYAAVGEAVSNVLYHN------ALVEG-PMAGVPDDKLLL----------------------GDLYS------DDKVVIAENCVTSEGPATAIALALTLVEL--------- +-----------------------TGCEEIEVAALCDILARGGVRVTVASVDGHLNH---IVK--LAK--------------GTDVQADKPIEFCVNDEYDIIAVPGGPGA-KTLGASQTLASLLKEQKSAGKLYAAVGEAVYDVLFHN------ALVEG-PMAGDPADKLVL----------------------SDLYS------DDKVVIAENCVTSKGPATAIAMAVTLVEL--------- +-----------------------VGSEEIEVAALCDILARGGVRVTVANVDGHLHH---IVK--LAK--------------GTDVQADKPIEFCVNDEYDVIAVPGGPGA-KTLGACRTLVNLLKEQKGAGKLYAAVGEAVYDVLFHN------ALVEG-PMAGHPTDKLVM----------------------ADLYS------DDKVVIAENCVTSEGPATAIAWAVTLVEL--------- +--------------------------------------------------------------------------------------------AVSPGMLDIVLIPGPPP--KAMPPAEEYLDFVRAHFAAGTAILSICTGAFIIGYS-------GIVKGREVTAPRLLVPEMRR---RFP------------E-AKLWDD-----SVRVARDGNLWTSGGITNGHDLVAG------------- +-----------------------QGLNILDLTGPAEVFGNPAFNLTIASATPQNPRATKSAE-GV-T-----I--ASDTSFQHLLQEN----AAQLARYDILVVPGAPPEDCALKNDSGLLEVVKTFAAKDRWLFSICTGAAFLGTE-------GVLGKKKATTHFAYLPIL---------------EEMTEKAGAEVV------RKRWVDAGRVVTSGGVSCGIDAALWILSH--------- +----------------------------------------------------------------------------------------------------TIILLGGHNP-EGFKLHPKYVDLIRRHISAGKLLFTTYTGSAVFAST-------GLLDGKNATINHAVYKWAKE---NYP--------------AVNWTK-----GETWVVDENIWTGAGAVAGIDMVASW------------ +----------------------SDGTDELETMILYDVLKRANIRVILASCSTRIVHTSHGM----------------------KLITTSPVEDSVDYNIDLIALPGGNA-LDGLRECEVLIKLLKKQLEKGKWIAAFSNAPAGVLMP------HLLLDG-KATCHPSKARDM----------------------TGYFV------DQDFAISKNCVTSQGQGTSMRCALKLVEL--------- +-------------------------IIPFHLSVPCAVFEKACYQLMICATHAGPLRTN----SGF------------------SIVAEHELAM--LAEADMVVVPSWSDPA--VAPPPALLQALQQAAQRGAQIVGLCLGAFVLGAA-------GLLHQQRATTHWRWMSDFER---LYP--------------DVTIDR-----DVLYIDEGQIVTSAGTAASIDCCLHLVRE--------- +-----------------------------------------------------------------------------------RIAPTHDIAHVQPGRLDILLVPGPDPG-GK--WEEDVLGFLRAHAEEGTDVLSVCTGVFLCGAA-------GLLEGRTVCGPRGVQDLLRK---KYP--------------GTKFVGE----RYRWVQDGNLWSGGGITNGNDLVAAYARR--------- +-----------------------------------------------------------------------------------SVRATHTYQDVAPGELDIVVVPGTDPA-DC--FTDDAKKWLRDQFNEGVDVLCVCTGVFLCGAA-------GILDGKSVSGPRGLQDDLRK---KYP--------------DAKFVGE----KYRWIQDGNLWSSGGITNGNDMMVAYAYA--------- +-----------------------------------------------------------------------------------SIVPTTTVDEC--PELDILLM-GGPNP-LTFELHPKFSEFIRRHVAAGKLLFTNCTGASVAAET-------GVLDGKNATVNNVEFEYAK------------------RKFNVKWTR-----DTKWVVDGNIWTGSGAIAGMDMFAHW------------ +----------------------FPGFDMIDVFGTLEPLQLMAMTLSLIAEKLDPVTTA-SNGP--M-------SKAKNSTFWPAALPNNTFGD--DLDLDVLIVPGGPGVR--NPDLPAVTDYIARMFPKVKIFITICTGSGLAARA-------GVLDGVMATTNKNAWETI----------------------------------------------------------------------- +-----------------------DGTFNTELTAPFDIFQHTRMNTFTVAQSKNIITTFE----------------------GLRLQPDYDFTNA--PRIDILVIPSAEHHLDSDLENTEVINWIKQTGSAATYITSHCDGAFMLAQA-------GLLDHVVSTTFL----------------------------------------------------------------------------- +-----------------------NGVLQSEVIATSDVFAKPSFNVISIAETQNPITTEE----------------------GMHFVPDYTFDNC--PILTALFVPSAYDM-YAQVHNEKIVAFIKEKNKETKYTVSNCAGAQLIGKS-------GIADGHKIVTWI----------------------------------------------------------------------------- +-----------------------PGFQALDVFGPVDCINVLSHSVTLISSTLEPVTTKTSAN-----------------AIGQSVVPTHTFATA--PPLDLLFVPGGLGTRGSSPVIEEAISYIRSIYPRLGYLITVCTGAALAARA-------GVLNGKRATTNKMAWAEI----------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------SLVLVVGNSNEVVDYPEARSVVQWLRAVPQSGTRMASICSGALLLAQA-------GCLDGRHCTTHHTLIADLQA----------------LAP-SAQVVS-----DRIFVDDGGVLTSAGITTGIDLALYLIEQ--------- +------------------------------------------------------------------------------------------------PEPQIVVVPAFTDPA--AAAEAPLRELVNRVHRRGGLVMSVCSGAKVLAAT-------GLLDGRRATSFWADLPGLRH------------------DHATTWLA-----GTRWVEDGSVLTTAGVSSGILGALHLVDR--------- +--SAKVAVVLSGC-GVY------DGSEVHEASAVMVHLSRGGADVAIFAPDVDQM---HVINHT--KGEPM--EEKRNVVESARIAKIAALSTLDVAGHDAVILPGGFGAAKNLKVNPEVEKTIKSFHDAKKPIGLCCIAPVLA--A-------KLIPGCSVTVGNDQEEGG----------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QPGALDVILIPGPEPS--TVP-DAEYLDLVRAHNAAGTHILSICTGILVVAHA-------GIAKGKHATGPRMMIPMLRE---KFP--------------EAQWDD-----SLRAVHDGNLWCSGGITNGHDLIAM------------- +-------------------------------------------------------------------------------------------------PGSLLVLPGVCDSNRATPQAEEVRRWLTRLHSQQLNLMCVCSGALLAARA-------GLMHGIQCTTHHDVLERLKA-----------------AAPGAQVKD-----NRIFVEDRGIWTSAGITSGIDLALHLINRY-------- +-------------------------------------------------------------------------------------------------EGATVVLAGTAELVLSDPPGEAIVAWLRAEVRPGHRLVSICSGALLAARA-------GLLDGHDCTTHHAACAELAA-----------------LAPAARVLE-----DRLFVEDRERLTSAGITAGIDLMLHLVARL-------- +----------------------------------------------------------------------------------------KLFNDV--LSPDIVLVPGGLGC-ERTAKDALMLEWLQAVQPQCQWMAASSTGTVVVAAA-------GLLDDHDAATHWLATPL-------------------LESYGSSAS------DERIVEVGRIITCEGKITAMHVALLV------------ +----------------------------------------------------------------------------------LRIAPDLSLDECTFEDTDLLILPGGST--WSEEIHQAILERAEQALQRGTIVAAICGATDALANR-------GCLNTRKHTSNNLAYTKM-----MCPNYK-----------GETFYQ-----LEVAVADDNVVTASGVA--------------------- +---------------------------------------------------------------------------------------TYDLQTC--PKPDIIVIPGANPDMKYIDFRETVLKWIKNQYDTGTVVFTVCTGSMLLSGT-------GILAGHNITTHSMLLDVL-------------------EQHEANVIR-----NVRYIDQEQLITTAGITAGIDAALYLIGKH-------- +----------------------RNGSVATDVMGPYSVFAGPKFDVRTVSSARSPVALSGGL----------------------TVMPEATYDDYRLPLPDLVVVPAITEPAG--SDEAELRAFIESVHAAGRMVMGVCAGARVLVET-------GVLYGKKATSFWSDLDGM----------------------------------------------------------------------- +-----------------------EKFDLLDFAGALEVFTTAAFEVTIVGPEPKVIS-DQGVVV----GSQ------------------ISYKEARLEDFDILVVVGGNSK-EVVAKELQPLSLITDFPARERTILSICTGALFLGKQ-------GILSGLSATTHPDFLTTF----------------------------------------------------------------------- +MAGKRALVILA------------KGAEEMETVIPVDVMRRAGIAVTVAGLAGKPVQCSREV----------------------MICPDSSLEDAHQGPYDVVLLPGGLLGAQN---------------------------------------------------------------------------------------------------------------------------------- +-TTQRIAFILT------------DACDLLGIGAIAEALECAKYEMQFLSERGGHIQCDRSMFV-----------------------STEELPDSSETRFARVFIAGGAQA-REACDAPRVAAWLQRVRAQGAPVRFLAAGVELGAAM------------------------------------------------------------------------------------------------ +-VKRRIAFVLS------------DFCDLLGVEVVAESLQHAVYPMQFLSARGGTVRSAQSLVV-----------------------STETLNEAMETRFSFVLVAAGPSA-LDICNILPQATWLQLMRALGTPVRFLSTGSEHTVAT------------------------------------------------------------------------------------------------ +-TTQRIAFVLT------------ESCDLLGIGAIAEALECARYEMRFLSQGGGHVKCDRSLFV-----------------------STDDLPKSGDERFAHVFVAGGTHS-RAACDTPALSGWLQRMRANGARVKLFAAGFEGT--------------------------------------------------------------------------------------------------- +-TTQRIAFVLT------------ESCDLLGIGAIAEALECARYEMRFLSEAGGHVKCDRSLFV-----------------------STDELPKNSDETFAHVFVAGRTHS-GAACDTPSLGGWLQRMKANGARIKFLTAGFEGT--------------------------------------------------------------------------------------------------- +-SKKQVAIVLP------------ETSDLLSVSTLAELLQYASYETHYLSPSGGYVRCAFSISV-----------------------STRSLDEALEHRFDHVLIASARQQ-KHIPFDAAHAPWLERMRSRGASIVMLSAGAGSAGAA------------------------------------------------------------------------------------------------ +-RLRQVAIVLF------------DGFDLMSASVIANTLELATYRIATLSDHAGYVASSAALRL-----------------------CAEAFDVHAEHEFDAIFAIVGSDA-YVDSRSAPLVAWINRARSKASDVRLVGATPPGLDDH------------------------------------------------------------------------------------------------ +-RLRRVAVVLF------------DGFDLLSASVIANALEAALYQITTLSDHDGYIASSAALLV-----------------------SAEAFDTHAGDEFDAIFAIVGADA-CIDSRSVPLIAWMNRARSKAADVRIVGAPLPGLDGH------------------------------------------------------------------------------------------------ +-APKRIGILIF------------EDFSLVEVSSISEVFSLADYALLFLSSDGGSVASSCSMRI-----------------------WTESLDTRWMSDCDALFIAGGEGA-QRAKLDAQLLRRLSRVAPKISFVKAIGEGSQILAAA------------------------------------------------------------------------------------------------ +-RDKRIGLLLF------------ENCSFLDIGLVVEIFSLAPYAVSLLSSRGGQIRCTNSITV-----------------------ETESLDATEPASYDVLFIADGEGA-SAAADDKRTTDWLKRVFQTVKVVQASGNGALLLKGA------------------------------------------------------------------------------------------------ +-EIQRIGLLLF------------EGCSLLTAGIIAEAFRVAVYQLSLLSYRGGNVACSSSIRI-----------------------WTQSLDALGQRGFNAIFIACSERE-PVVERDARLMTAMLEISAMVLERSRAGREPILPRVS------------------------------------------------------------------------------------------------ +-RRYQIALLIL------------DGCPLSDAATIAETCQLVGYNVCMLSTHKGFVSCASAIRL-----------------------FAENIDDFDSRRYKAIFVGGGNGI-----HDRRVIDWLKRAGDDVELIAISPDAHAMLAAT------------------------------------------------------------------------------------------------ +-MVKRIGILVF------------ERFPLSDVCLLADAFRLASYSIVMLSEMGGSVISSCSLRV-----------------------WTESLNGPLLNGFDTLFIVGGPGA-SRAKANERLIRRLRAIAPKIRVVKALDEGLGVLAAA------------------------------------------------------------------------------------------------ +-AAKRIGILIF------------EDFSLVEVSSISEVFSLANYSLMFLSSEGGSVASSCSMRI-----------------------WTESLETRWMNECDALFIAGGAGA-RQARHDAALKKRLGRVAPKIPFIKAIGEGALMLAAA------------------------------------------------------------------------------------------------ +-TPQVIGIVVF------------DGFSMLPAAEVADVFDKAAYRTVFVSRYGGCVSSSAHIDV-----------------------LTQSADFFG--KTRALFIASSDAE--STAQHGQVEGWLCKAAVGIDEIISIANAGP----------------------------------------------------------------------------------------------------- +--MKHIGLFVF------------QDCSMASTGAIGDAFRLAPYRFTVVSDGGGLVTSSSGISI-----------------------WTQGLERYCLADFHAFFVACRDVT-EVAESNDRFLSWISLQGSIASFGMQQGA-------------------------------------------------------------------------------------------------------- +---------------------------MATAGAIGDAFRLAPYRLSVLSESGGLVTSSSGISI-----------------------WTQSIERNRLGDFHALFVACRDAA-RALESNDRLLSWIARQGSIASFDIQQGA-------------------------------------------------------------------------------------------------------- +---------------------------MLTTGAVGDAFRLAPYRLSVLSDEGGLVTSSSSILI-----------------------WTQSLERYSLADFHAFFVACRDTT-GTAESNGRFLSWISRHGSIASRGVQQGA-------------------------------------------------------------------------------------------------------- +---------------------------MVTTGAIGDAFRLAPYRLSVLSDSGGLVTSSSTISI-----------------------WTQMLERYSLADFHAFFVACRDAT-EAMESSDRFLSWISRQGSIASFGVQQGA-------------------------------------------------------------------------------------------------------- +-PSMHIGLLVS------------QNFFTASAGAIGDAFRLAPYRLTVLSEEGGLVTSSCGISI-----------------------VTEQLRRYSVSDFHALFVACRDAS-VVTEPNNRLYSWITRQGAVASLRITQGS-------------------------------------------------------------------------------------------------------- +-PPRHIGLLVS------------QNFFTASTGAIGDAFRLAPYRLTVLSEEGGVVTSSCGISI-----------------------FTEQLSRYSVGDFHAFFVACRDTA-APTEPNDRLHSWITRHGAMASLRITQGS-------------------------------------------------------------------------------------------------------- +-TKKRIAILVY------------ENCSFVEVALIVETFDLAHYSISLLSSRGGRVQCSNAISM-----------------------DTHPLDASSSSGYDALFIAGGEGA-AAAAHDSRNTDWLKRVFQTVRVVQAAGNGTLLLKGA------------------------------------------------------------------------------------------------ +-VIKHIGIVLY------------DGFSLLAAGTLAEALHVAKYRVNLVSARGGTVSCSASMSV-----------------------WTDQLAGGKFDSLDNLFVAGGSGV-ARASSDDNLMELLRRASGKSVTITAMGNAHMLLSAA------------------------------------------------------------------------------------------------ +-AVKHVGIVIY------------DGFSLLAAGTLAEALHVATYRVNLLSVRGGTVSCSSSMSV-----------------------WTEQLAGREFDSLDNLFVTGGSGV-ARASADDGLIDLLRRVSAKSVTITAIGNAQMLLSAA------------------------------------------------------------------------------------------------ +-AARRIGVLLF------------DGFWLLGPGTVVEMFQTAPYEVQFLSLDGGSVPSSSAARI-----------------------WTDRIDTRFGTGFDVLFIAGGHGA-HQAARDQRLLGWLRTVQARTRAIETIGEGRLVLEAA------------------------------------------------------------------------------------------------ +-AARRIGVLLF------------DGFWLLGPGTVVEMFQTAPYEVQFLSMDGGSVASSSSARI-----------------------WTDRIDTRYGSGFDVLFIAGGYGA-HEAAQDERLLNWLRSVQTRTRAIETIGEGRLVLEAA------------------------------------------------------------------------------------------------ +-TAKRIGIVLF------------GGFALPEAAAIAEVFHSARYDVSLLSAAGGRVASSSSVFV-----------------------WTEGIGVQRESRFHALFIAGGGGV-IDALRDEHLIAWLRRTYRRGELVFPIGEGRALLDAA------------------------------------------------------------------------------------------------ +-AKKRIGIALF------------NGFSLPEAATVVEIFQSACYDVHLLSMDGGRIASSSSVFV-----------------------CTDTIKSGGRTEFHALFIAAGAGV-HSMLSEERLVAWLHRLDLRSERIFPIAEKRLLLDDT------------------------------------------------------------------------------------------------ +-TVRQIGILAF------------DGFSLLGTSAISEIFQIAPYNVTFYSGKGATVQSSSLIDV-----------------------WTHACDPSDVQALDAVFIADGPGV-QDALQDTRVMDWLSELLSRRKLISPIGNGKALLDIA------------------------------------------------------------------------------------------------ +-QMHSIGILIF------------DGFSMLPVAEVIDVFDKACYRTAFVSRHGGCVSSSAELAV-----------------------MTQRPEQLP--SVRTLFVACGGEV-PKVAADLQFRNWLCETACRADEVFAIGNGDSLLSAI------------------------------------------------------------------------------------------------ +-AVKRIGIALF------------NGFALPEAATVVEIFRSALYDIYLLSVGGGRIASSSSVFV-----------------------WTDSIESRGYAEFHALFIAGGAGV-HNMLSEERLIAWLRWLDLRSEKIFPIAEGQLLLDAA------------------------------------------------------------------------------------------------ +-SARRIGILLY------------EGFSLFGAGLVAELFQTATYDVRFLSVEGGSVTCSAAVRV-----------------------WTDSLEPRRPAGLDMLFIAGGEGA-RAAASDTRLLCWLRAACSTTDSVRPIAEGRAVLAAA------------------------------------------------------------------------------------------------ +---------------------------------MAELFQTAAYDVRLLSVDGGSVACSASVRV-----------------------WTDGLDPRQFIGFDVLFIAGGAGA-HAAAADERLLRWLRVVSPRTPTVRPIAEGRAVLAAA------------------------------------------------------------------------------------------------ +-VVKLIGILVY------------DGFSLLGAATLAEALRFATYSVRLVSARGGAIACSSSVCA-----------------------WTERLGGNRFLGFDALYVAGGSGV-TRAAADEGLTALVRIACSQSAVVSALGSGDVLLAGA------------------------------------------------------------------------------------------------ +-STKLIGIMLY------------DGFSLLGAGTLAEALHIATYSVRLVSARGGAIACSSSVCV-----------------------WTERLGGQRFQGFDALYIAGGAGV-TRAAADESLLESLRIACSQSGAVGSLGNGDALLAAA------------------------------------------------------------------------------------------------ +-EVRRIAILLF------------DGFSLLGAGIVAEVFHVATYDVRFLSVEGGNVACSSSVRV-----------------------WTDGLDARHYGGFDALFVAGGKGA-DGAAGDERIVEWLRRVHSKTTVVKSIAEGRKVLDAA------------------------------------------------------------------------------------------------ +-EVKRIAILLF------------DGFSLLGAGIVAEVFHMATYDVRFLSVEGGNVACSSSVRV-----------------------WTDGLDARHYGGFDALFVAGGRGA-EEAAKDDRIVEWLRRVNGKTTAIKSISEGRKVLEAA------------------------------------------------------------------------------------------------ +-MTRHIGVVVY------------KAFSLPSIELVPEVFQMAFYRVRLYSADGGSVLSSSSIVV-----------------------WTLGLQTIDASAFDALFIAGGKGA-QDALRDGRVIDWLQAASPSSDVVRPIGEGRLLLRAA------------------------------------------------------------------------------------------------ +-LRKHIGLLIA------------PHCSMAAAGAISDAFCLAPYRFTVLSEGGGFVTGGASFPI-----------------------WTQKLDRYQLSDFHAFFVACSGDP--TTESSEQLVAWLSRQGPGAPACTRQKT-------------------------------------------------------------------------------------------------------- +-FEKHIGLLIA------------PHCSMAAAGAIGDAFCLAPYRFSVLSETGGFVTGGASFPI-----------------------WTQKLERFQLADFHAFFVACSGDP--MTESSEQLVSWLSRQGSGAPPCMRQKT-------------------------------------------------------------------------------------------------------- +-EIRNIGILIF------------DGHHLITASVINEIFHLAPYRITLLSKLGGPVSSSSSISV-----------------------MTKSLAAYRVGDFHALFVASNDVR-VKSGLDAQLSAWLAGAGNAPQRVRRFAP-------------------------------------------------------------------------------------------------------- +-TDRVVVIFLY------------ESFSLADVAAVADVLSVARYVVRLMSTRGGVMASTSGIRV-----------------------WTDGLDARYFGSTDTVLIAGGPGA-RAASEDFGLVGWLRKIGPSTRTVCAVGEGSMVLEAA------------------------------------------------------------------------------------------------ +-AVRQIGIVLF------------DQFSLTEVSGITEWLDCVRYALTMLSSAGGCVTSMSGVQI-----------------------WTESIGLHSGGEFHMVLVAGGAGA-PAATLDDALHLWLHDAARSGQVYSMRRDGGDIIAAA------------------------------------------------------------------------------------------------ +-SVVKIAIVVF------------AGFSIKEVDALADIFNRVIFNVSLLSIGGGYVDDSLSIRI-----------------------WTDPVEPRLSEKFDGVFVVGAKCR-LRAAEEPDVLRAMSTLVARADVVVWDSDSSLVMASP------------------------------------------------------------------------------------------------ +-YRKGIAVVLF------------GGFSLMQAGRMAEIFNLAGYEMLLLSATGGAVYSSSGIPV-----------------------WTQPLHERAIERVHAIFAIGEPDA--ADRDDEKVSEWLRSARAHVR----ASGGARRLMGL------------------------------------------------------------------------------------------------ +-YRKGIAVVLF------------GGFSLMQAGRMAEIFNLAGYEMLLLSAAGGAVYSSSGIPV-----------------------WTQPLHEHAIESVHAIFAIGEPGA--CDRDDATVSEWLRSARAHVR----ASGGKRRLMGL------------------------------------------------------------------------------------------------ +-ALTRIDIALF------------NGFALPTVAALIEIFQRARYDVSLLSAAGGRIASSSSVFV-----------------------WTDDVQSHRGTEPHLLFIAGGAGV-QQACRDERLSEWLRRRHPFSEIVHPIAEGQLLLQAA------------------------------------------------------------------------------------------------ +-APTRVDIVLS------------NGFALHDVAAIIEIFHKARYDVSLVSAAGGRIAASSSVFV-----------------------WTESIDSRRRVGKQIMFVAGGAAA-DPACRDKRLIDWLRRQHQLCETVHPIANGKLLLDAA------------------------------------------------------------------------------------------------ +-TLTRVDIALF------------NGFALPSVAAIVEIFQKARYDVSLLSAAGGRIASSSSVFV-----------------------WTGDVQSHRGTDTHLLFIAGGAGA-KQACRDERLSNWLRQRHPFNQIVHPIAEGQLLLQAA------------------------------------------------------------------------------------------------ +-PLTHANILVF------------DGFALPDVSVVVEVFHKALYEVTLRSAAGGRIASSSSVFV-----------------------STEGLDVHRPADREVIFIAGGPKA-HEACTDVRIVDWLRHQQSCSTRIEPIAEGRCLLEAT------------------------------------------------------------------------------------------------ +-ELTRVDIALF------------NGFALPKVAAIIEIFQKARYDVSLLSAAGGRIASSSSVFV-----------------------WTESVDSHQVTDRHLLFIAGGAGV-PHACRDERLSNWLRRRHPFSEIVHPIAEGRLLLEAA------------------------------------------------------------------------------------------------ +-EVTHVDIALF------------NGFALPKVAAIIEVFHKAYYDVSLLSAAGGRIASSSSVFV-----------------------WTESVETHRGTDRHLLFIAGGAGV-EHACRDERLSAWLRRRHPFSEIVHPIAEGRQLLEVT------------------------------------------------------------------------------------------------ +-SMKHVGISLY------------DGFALPDAAQIMEVFQSANYDVRLLSAAGGRIASSSSVFV-----------------------WTESVEAYRGDCFHALFIVGGAGL-RNALSNERLIRWLRRACSNSGLIFPVGEGRLLVEAT------------------------------------------------------------------------------------------------ +-ASVDVEIVLF------------DGFSLPGVAAVIEIFQRAPYNVSLLSASGGSVVSSSSVHV-----------------------CTENTAAQRASPTILLFIAGGAGA-ERAACDERLSAWVRQRHAVSTIVCPISEGQLILDAA------------------------------------------------------------------------------------------------ +-EFVRVNIALF------------NGFALTKIAALIEIFQKAHYDVSLLSAAGGRIASSSSVFV-----------------------WTESVESHRSTDRHLLFIAGGAGV-QQACRDLRLVDWLRCRHPFSEIVHPIAEGQLLLDAA------------------------------------------------------------------------------------------------ +-QRASVIVLLL------------EGFSIMQMGKLAAVFELARYELRLYSVHGGPVRSSSGVGI-----------------------WTEAARTLGASTVHAMFVLSGQDG--IDALDEQLIAWLRHAHQRARVVRGSHGGRKLLTQI------------------------------------------------------------------------------------------------ +---------ML------------DGFSIMQMGRLAAVFELARYELRLYSSHGGAVRSSSGVQI-----------------------WTDAPRPLDASSVQAMFVLGGQGR--ASGLDDQFIGWLQHVHQRARVVKGNSGGAEMLTGI------------------------------------------------------------------------------------------------ +-PRECVIVLLL------------DGFSVMQMGRLAAMFEHARYELRLYSAHGGPVRSSSGVQI-----------------------WTDAPRMPDASMIHAMFVLGGEDL--ASDHDDSLVAWLHNAHQRARVVKGASGGGKLLARI------------------------------------------------------------------------------------------------ +-NINLVDIVLF------------DGFSLPDMAAVIEIFHKAEYDVSLISTSGGRIASSSAVYV-----------------------WTEGVESHRAQQMDRLFIAGGIGA-HRALHDDRLLLWLREACRVSTTVHPIAEGRLLCDAA------------------------------------------------------------------------------------------------ +-NTKHIGVALF------------NGFALPDVASLIEVFQSAHYEVSLLSASGGRIASSSSVFI-----------------------WTDGVGSLRQDHFHALFIAGGIGA-TTAFRDDRLIVWLRRVFAGTTLVHAIAEGRLLLDAA------------------------------------------------------------------------------------------------ +-SAKHIGVALF------------NGFALPDVASIIEVFQSAHYEVSLLSASGGRIASSSSVFI-----------------------WTDGVDSLRRTNFHALFIAGGIGA-TTAFRDDRLIVWLRRVFPTSALVHAIAEGRLLLDAA------------------------------------------------------------------------------------------------ +-TVKRIGIVLF------------GGFALPETAAVVEVFQSVRYDVSLLSVTGGRIVSSSSVFV-----------------------WTEGIDVRRDQRFHALFIAGGAGV-NDALRDERLIAWLRRMHPRADLVFPIGEGQLLLDGA------------------------------------------------------------------------------------------------ +-SVNHIGIALF------------NGFALPDVASIIEIFQSARYEVSLLSASGGRIASSSSVFV-----------------------WTDSVESRGNGNFRALFIAGGTGA-TNAFLDDRLIVWLRQAFPKSGMVHAIAEGRLMLEAA------------------------------------------------------------------------------------------------ +-AAKHIGIAVF------------NGFSLLDTVSIVEAFETARYVVRLLSSAGGRIASSSSVFV-----------------------WTDSVEARGHADFHALFIAGGTGV-HDAARDGRLLAWLRRTHLRSENVLSIAEGQFLLEAA------------------------------------------------------------------------------------------------ +-MVRHIGITLF------------NGFALHEAVTIGQAFQSALYNVSLLSVAGGMIASSSSVLV-----------------------WTESVDARAVTNFHALFIIGGNGI-RGALRDERLIRWLQRTVPRSQLTYSITEGRLLFEAA------------------------------------------------------------------------------------------------ +-RIRDIGVVLF------------DGFSLLTTGVIPEVFQVALYEVRFYSAEGGSMVWSSSISV-----------------------RTYPCDAERAMGFDALFIAGGEGA-MRAARDRRVIDWLRRVLPLTAVVKAIGEGRVLLEAA------------------------------------------------------------------------------------------------ +-KSREIGVVVF------------EGFSLLAAAAVCEVFEAALYDVRFYSSRGGNVVWSSAVSV-----------------------RTFACDAALADTFDAVFVAGGEGA-RRAARDARVIDWLRVVVPKAGMVETISEGRMLIDAA------------------------------------------------------------------------------------------------ +-KNRDIGFVVF------------EGFSLFAAGAVFEVFEVALYDIRFYSSKGGNIVWSSAISV-----------------------RTFACDSGSAHAFDALFVAGGEGA-RRAARDARVIDWLRIVLPKAGMVETIGEGRMLIDAV------------------------------------------------------------------------------------------------ +-ETRDIGVVVF------------DGFSLLAAGVVTEVFEMALYDVRFYSSDGGSVAWSSAISV-----------------------RTYACDAGSARAFDALFVAGGEGA-RRAARDARMIDWLRTVVPQTGIVRTIGEGRMLLDAA------------------------------------------------------------------------------------------------ +--MRRIAILMF------------NDCSLQGAGVVAEVFQAALYDVSFLSADGGMVMSSSALRV-----------------------WTDGIDARHYGGFDALFIAGGKGA-GAAAADERLIAWLRSVRRNTGMIRPIGDGRVLLDTA------------------------------------------------------------------------------------------------ +--MRRIAILMF------------NDCSLQGAGVVAEVFQAALYDVSFLSADGGMVTSSSALRV-----------------------WTDGLDARHYGGFDALYVAGGKGA-FAAAGDERLIAWLRRVRRNTGMIRPIAEGRALLEAA------------------------------------------------------------------------------------------------ +--VRRVAILLF------------NDCSLQGAGVIAEVFQAALYDVSFLSADGGMVSSSSGLRV-----------------------WTDGLDARHYVGFDALYVAGGKGA-ASAARDERLLGWLRRVRRNTAMIRSIAEGRAVLDAA------------------------------------------------------------------------------------------------ +-ATRHIAILLF------------DGCSLLGAGIVAEVFHAATYDVSFLSAAGGNITCSSSIRV-----------------------WTDGLDARHYMGFDALFVAGGKGA-RAAAHDERLIAWLRRVHANTSTVRPIGEGRSLLEAA------------------------------------------------------------------------------------------------ +-VTRRVAILLF------------ENCSFAVTVMIGEIFQAARYELRFLSATGGNVKCSSSICV-----------------------WTDGLDSWHCQGFDALFVSDGAGA-NVAARDERLIAWLRRVHANMIAVRPLGEGHTLFQQV------------------------------------------------------------------------------------------------ +-SVKHIGVIVS------------EGVILADLAEIAEVFFVTGYHFSLLSVRGGMITTSSSVQI-----------------------GTLSLQHHDIRAFDSIIIADGRGN-FADCNDPQLLNWLATAALHAPRIAALCTGVLVLAEA------------------------------------------------------------------------------------------------ +-SIKQVGVIVS------------DGVILADLAEIAEVFFVAGYHFSLLSVMGGMITTSSSVQI-----------------------GTLALKHVAMSAFDSIIIADGRGN-FAEYRNQQLLQWLRTPTADPRRIAALCTGVFVLAGA------------------------------------------------------------------------------------------------ +----------------------ANGSEEMEALQLVDILRRAGANVTVASVEDTPRIVT---RHQ-----------------KLGLVADVLIEEAAEMQFDLIVMPGAYV----------------------------------LQPH-------GLLKGKKATPFPPMAHLL-------------------KDRSA----C----EYRVVVDGNVITSKAPGSATEFALAIVHKLF------- +---ARVALVLSGC-GVY------DGTEIHEASAVLVHLSRGGAEVQIFAPDVPQM---HVIDHT--KGQP-SESESRNVAESARIAKITNLAQLNVANHDAAIFPGGFGAAKNLKVNKEVERVLKEFHGAKKPIGLCCIAPVLAA---------KVIKGVEVTVGHEQEEG------------------------------------------------------------------------ +-----------------------DGVDVLDFAGPLEIFSHVHYGMDYTAPDPAFKL--TTIGADVIST-----------SAAVKIIPDVSVAYSKLDEFDILVVPGGPPSIVALKSNSEVLQIVKDFVRRPRTILSICTGAHFLGAC-------GLLSGLSATTHHLFLDDL----------------------------------------------------------------------- +----------------------PSGCYLPDFLGAVEVLSAPNSTLHVVSHDKTPVQCL--L--------------------GPKVVPTTSFEDC--PQVDFVIMGA-TQ--PFLLKDKQLLDFVRRQEPNAKGMISVCAGTLVYATA-------GLLNGRTATSNYHHTPL-------------------LDKLGARSS------GTEVAYDGKFYSAGPAIGSYEVALRAVQ---------- +-----------------------PGFSALGFMSAVEPLRVALYHWRIVSCDGAPVVASNGI----------------------SLNADAAFAQV--EHAHTIFVIAGFDPLA--RYTRALGDWLRREYRQGATAGGIDTGSFVLAEA-------GLFDAHALTLHWEALAAFQE---RYP---------HLK-----TT------QELFEIDARRITCAGGTASIDMMLDLIG---------- +-----------------------PGVTQLDFTGPYEVFSRPNVKIFLFAQSKDPVQSESGM----------------------KLIPDFDFADC--PDLDILLVPGGPGT-TLLMEEFTVLDFLKR--------------------------------------------------------------------------------------------------------------------- +-----------------------PGLTALDVVGPYEVLRYPEADVRFVWHETGPVVTDSGV----------------------LAGATHTFDET--PSPDIVLVPGSGTA-IAVAADKRLREWLRS--------------------------------------------------------------------------------------------------------------------- +---GTVAVILSGC-GYL------DGSEITEAVSVMVHLSKKGYKLAFFAPDINQEETYDHLTKNVEKN------EVRNIASRITRQNVLRLDQFRPQAFEALIIPGGFGVAKNLSIHPEVEKAIVSTHEAKIPIGMCCIAPVLAAKA------------------------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------KIVPNVTYDTC-PRDLDIVVIGGPFP-T--F-RPAGADKFMKEAWSKTRVWLTTCTGALWLAST-------GKLSGHKATANRAAVPIAQQ---MYP--------------DVQWL------DQRWVVDGELWTGGGAGAG------------------- +-----------------------------------------------------------------------------------LVKPTHTYENA-PRDLDILLLGRPSE-F----------GVLKEASLRTKVIMTTCTGAVWLAKS-------GVLDGKKATTNRAMIPLAKT---MAP--------------NVEWV------DQRWVIEAEIWTAGAAGCG------------------- +-MSKKVAIVLSGC-GVY------DGSEIHESSAVLVHLSREGAQGEFYAPDVEQM---HVVDH--VKGQPT--QEKRNVVESARIANIKDLATLNVKELDALII------------------------------------PVLA--A-------KIFPGCELTVGQDKECEKW----------PYKTAEAMKELGCKHVNKH---VGEIHVDNKLVTTSAFMC-------------------- +-------------------------------------------QVKIFAPNVEQM---HVVDH--LRGSPT--DEKRNVVESARIAEIQDLADLKVSEFDAVILPGGFGVAKNLCSWAVDGKTLQAFHSAKKPMGLCCISPVLV--A-------KIFPGCEVTVGYDKDVGRF----------PDETATAIKELGCRHVCKD---VSESHVDNKIVTTCAFMC-------------------- +-------------------------------------------KVKIFAPNAEQM---HIINH--LKESPT--EEKRNVAEGARRADAQDLADLNFSELDAVRIPGDFGVAVMSLCLSIQPTALPAFHCARKPISWCCISRCWQ--L-------K-LPACEVTVGQENIVGGF----------VDDPAT-AQKPRCKHSCSQ---VRGSCQFNKMMQTCAF---------------------- +------------------------------------------------------M---HVINH--LKGEVD--SHSRMVPESARIANIQSICELNISCFDAVIFPGGFGVAKNLSDYAIKGAVIQEFHNAKKPQGFLCISPILA--A-------RVLCTVKITLGKNS-CDKW----------PHGAIEDAKKMGATVELRN---WDEVSFDNLIFSSPAYMY-------------------- +---------------------------------VLVHLSRGGAEVQIFAPNVPQM---HVIDH--TKGQPS--EETRNVAESARIAKITDLAQLSAANHDAAIFPGGFGAAKNLSTFAVDGKVLKDFHKAGKPIGLCCIAPVLA--A-------KVLPGVEVTVGHEQEEGKW----------PYGTAEAIKAMGAKHCVKG---VTEAHVDNKVVTTPAFMC-------------------- +----------------------------------------------------XQM---HVIDH--TKGQPS--EESRNVTESARIAKITDLANLSAANHDAAIFPGGFGAAKNLSTFAVDGKVLKEFHQAGKPIGLCCIAPVLA--A-------KVLRGVEVTVGHEQEEGKW----------PYGTAEAIKALGAKHCVKE---VVEAHVDNKVVTTPAFMC-------------------- +---------------------------------MLIHLSKAGVDVCAFAPNIQQD---HVTNH--STGSQV--PEKRNVVESARISKIAPLSELKSEGFDALFIPGGFGAATTLSNFVSDGAVLTEFVHAKKPIGLCCIAPVLA--A-------RCLPGVHVTTGTDTGT-----------------AMAIKKMGAVHENRE---ITEVCIDLKVVTAPAYMC-------------------- +-------------------------AEPRQALAGLVMLVQECIPVKIFAPNIEQR---DVVNH--LKGSPT--DEKRNVVESARLANIQDLAELKVNEFDAVIFPGGFGVAKNLCSWAVDGKTLQAFHKAKKPIGLCCISPVLA--A-------KVFPGCEVTVGQDKNVGRF----------PDETASAIAELGCKHICKD---VSESHVDNKIVTTCAFMC-------------------- +-MGKRVAVVLAGC-GVY------DGSEIHESSAVLVHLSREGAEAEVYAPDVEQM---HVVDH--LKGQPT--QEKRSVVESARIANIKDLAKLDVQRLDALIIPGGFGVAKNLSTWATQGKVLRAFHAARKPIGLCCISPVLA--A-------KIFPGCELTVGHDTECEKW----------PYKTAESIKGLGCQHINSQ---VTDIHVDNRLVSTSAFMC-------------------- +--MKCVAVVLAGC-GVY------DGTEVHEASAVLVHLSRAGAKVQMFAPNVDQM---HVVNH--IVGKPT--EEKRNVQESARIADIMDLSKLDVSAYDALIIPGGFGVAKNLSTWATQGKAIKSFHKAGKPIGLCCIAPVLA--A-------KTLPGCEITVGHDCKCEKW----------PYQTACTMKEMGCKHVNKN---VGESHVDNKLVTTSAFMC-------------------- +-MGKRVAVVLAGC-GVY------DGSEIHESSAVLVHLSREGAQAEVYAPNVEQM---HVVDH--VKGQPT--QEKRNVVESARIANIKDLAELDVKGLDALIIPGGFGVAKNLSTWATQGKVLKAFHAANKPIGLCCISPVLA--A-------KIFPGCELTVGHDTECEKW----------PYKTAETMKELGCKHVNKH---VTEVHVDNKLVTTSAFMC-------------------- +-MRKHVAVILAGC-GVY------DGSEIHESSAVMVHLSRAGAQVEIFAPNIIQM---HVVDH--IKGQPT--QETRNVVESARIANIKDLIMLKVTEFDALILPGGFGVAKNLCTWAVKGKVITAFHAAKKPIGLCCISPVLA--A-------KIIPNCELTVGQDTKCEMW----------PYETACALKELGCKHVNKR---VKEAHVDNKLVTTSAFMA-------------------- +-MAKRVAVVLAGC-GVF------DGSEIHEASAVLVQLSRDGAQAEVYAPNIPQM---HVVDH--VKGQPT--PEQRNVVESARIANIKDLATLDVKELDALIIPGGFGVAKNLSTWATQGKVLRAFHAAHKPIGLCCISPVLA--A-------KIFPGCEVTVGHDTECEQW----------PYKTAEAMKELGCRHINSQ---VSQVHVDNLLVSTSAFMC-------------------- +-MAKRVAVVLAGC-GVF------DGSEVHEASAVLVHLSREGAQAEVYAPNIPQM---HVVDH--AKGQPT--PEQRNVVESARIANIKDLATLDVKGLDALIIPGGFGVAKNLSTWATQGKVLRAFHAAHKPIGLCCISPVLA--A-------KIFPGCEVTVGHDTECEQW----------PYKTAEAMKELGCRHVNCQ---VTEVHVDNRLVTTSAFMC-------------------- +-MGKRVAVVLAGC-GVY------DGSEIHEASAVLVHLSREGAQAEVFAPNISQM---HVVDH--VKGQPT--PEQRNVVESARIANIKDLAQLDVKGLDALIIPGGFGVAKNLSTWATQGKVLRAFHAAHKPIGLCCISPVLA--A-------KLFPGCEVTVGHDTECEKW----------PYKTAESLRELGCKHVNSH---VSEIHVDNRLVTTSAFMC-------------------- +-AKKSVALVLSGC-GVY------DGTEVHEASAIMVHLSRAGAEVTIFAPDVEMM---HVVNH--CEGKPV--ADKRNVQESARIADVTDLAKLDVSAFDALIIPGGFGVAKNLSDWATKGKVIKGFHQAKKPIGLCCISPVLA--A-------KAIPGCELTVGHDKVCKMW----------PYQVAQSMAELGCKHVNKH---VGEVHVDNKLVTTSAFMC-------------------- +-ASHRVAVLLAGS-GVY------DGSEVHEASAALVALSRHDAQISCFAPDKPQL---HAINH--CAGAPH--EETRNVQESARIANVTDLKELNVEDFDALLVPGGFGAAKNLSDWALKGPKITAFHSAKKPLAFCCIAPHLA--A-------KLIPGCTVTVGSAGKN-----------------GGAIEKLGCKHVEKT---VSETCIDNKIVTSPAFMY-------------------- +-MVKCIAIVLSGC-GVY------DGTEIHEASAVLVHLSRAGAKVQMFAPDVDQM---HVVNH--CEGKPT--AEKRNVQESARIADVSDLTKLDITAFDALVIPGGFGVAKNLSDWAVKGKLIKGFHGVGKPLAMCCISPVLA--A-------RALPGCEITVGQDSECERW----------PYQTATTMTELGCKHVNKN---VGEVHVDNKLVTTSAFMC-------------------- +-MVKRVALILAGC-GVY------DGTEIHEASAILVHLSRAGAKVQMFAPNVEMM---HVVNH--CEGKPS--NEKRNVHESARIADVSDLAKLNVADFDVLIIPGGFGAAKNLSDWATKGKIIKSFHQAGKPIAMCCIAPVLA--A-------KAIPGCEITVGHDCECEKW----------PNAVAKSMEELGCKHVNKN---VEEVHVDNKLVTTSAFMC-------------------- +-VKKRVAVILSGC-GVY------DGSEVHECSAVMVHLSRAGAEVQFFAPNVQQM---HVVDH--VSGQPT--EDKRNVVESARIADIKDLTLLCVNEMDALIVPGGFGVAKNLSSWATKGKAMKKFHATKKPIGLCCISPVLA--A-------KLIPGCELTVGQDTECEMW----------PFKTAHSMKELGCKHINKH---VHEAHVDNKLVTTSAFMC-------------------- +-MVKRVAVLLSGC-GVY------DGSEVHEASAVLVHLSRAGAKVQMFAPNVDQM---HVVNH--IEGKPT--EEKRNVQESARIADISNLKSLDISAHDALILPGGFGVAKNLSTWATDGKAIKSFHKAGKPLGLCCISPVLA--A-------KLLPGCEVTVGHDSECEKY----------PYQTACAVKELGCKHVNKN---VGEVHIDNKLVTCSAFMC-------------------- +-KTRKIAVLLAGC-GHL------DGAEVREAVLTLLALDQHGAAFQCIAPNAPQF---HVINH--ITGEPV--AAQRNIEESSRIAQCLDLAKAKVADYDALVMPGGYGVAKNNCSFAFKGAFVRGFFDAKKPVGAICIAPALV--A-------LALHQVTLTLGNDAGV-----------------AAAMGQLGQRHQNTP---NARIVIDHKLVTTPAYMF-------------------- +-MVKKVAVILSGC-GVY------DGSEIHEASAVLVHLSRDGAQVAFFAPNVTQM---HVIDH--TKGQPS--DEKRNVVESARIADIQDLDQLKVGELDALIIPGGFGVAKNLSTWAENGKTIKAFHAAKKPIGLCCISPILA--A-------KILPGCEVTVGQDQECERW----------PHKTADAVKELGCKHINRN---VNEIHLDYKLVTSCAYMC-------------------- +-----------------------------------------------------------------------------------RIAPTDTFETCP--PLDIVLI-GAHN--FGYTPNDSELRFVRKSWEMSSAFLTICAGVEVPLQA-------GLLEGKTVTGPRFLLN-------------------ELRRNGSNWV------EKRWVRDGKLWTSGALLNGADLMHNF------------ +-----------------------PGVTALDVVGSWEVLSRPDTEIRFVGKEAGPVMSEGD---AL------------------LLGAAYTLTET--LSPDIVVVPGGLTTPRQM-VDDEVLAWLRKVHQTTIWTISVCTGALILAWT------------------------------------------------------------------------------------------------ +-MTKKVLVPIA------------PGTEEMEAITIIDIMVRAGFEVTVASADGALMKASRG----------------------VTLTADCKLVDVADDEFDVIALPGASAVLKCFV---TVHYWSRWFA------------------------------------------------------------------------------------------------------------------- +-MSASALVCLA------------PGSEETEAVTTIDLLVRGGIKVTTASVAGNLITCSRG----------------------VKLLADAPLVEVADGEYDVIVLPGGIKGAECFR---DSTCWLKPLN------------------------------------------------------------------------------------------------------------------- +------------------------------------------------------------------------------------------------SEFHILVIPGGPPAVLPIEKNAPELDLIRKYAAATRTLLSVCTGAFLLGAA-------GVLSGMTVTTHHHALDRLR---------------------------------------------------------------------- +--NPKVALIFSGC-GVY------DGTEIHEASSAMVHLSRHEAEVGIFAPNIEQMH---AIDHT--KGEPMEVN--RNVVESARIAKIQDLKDLKVQDFDAVIFPGGFGAAKNLSVQPSVEKVIKEFHSAKKPIGLCCISPVLAAKT---------IPGCTVTVGQ----------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------EEVAPGNLDIVVVPGPDPAA---KIDEAGLQWLKAHFDTGKVILSVCTGLYVCAAA-------GIADGRLASGPRDFQEDLRA---RYP--------------KIKLVGG----KQRWVQDGNFWSSGGVTNGNDLMAA------------- +--------VLSGC-GVY------DGTEIHEASAILFHLSRKGAEVQMYAPDVLQMH---VVDHT--KGQP-AEAESRNVTESGKITN---LAKLTTQDHDAVIFPGGFGAAKNLSVHREVERVLQEFHKAGKPIGLCCISPVLAA---------KVLPGAEVTVGHEAEEGG----------------------------------------------------------------------- +-----------------------DDFEALDLFGPVEFLSGPDAQLSYVSMDGGLISTKQGIQ----------------------LY-TQTMRD--LESWAILLLPGGRGT-RKVIENPLFLERLNELVNRSRWVLSVCTGSALWLEV------------------------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------TIKPTTTCATC--PKLDYLLIGGPYP-EFFLNVPDVFANFIRERVDEVKGVFTTCTGGMVAAMV-------GVLDGKTATTNHQYLAAAKK----------------LK-PDVNWSS------KQWVVDGKFWTAGGALAGMDMFAHWV----------- +-----------------------------------------------------------------------------------TIKPTTTCATC--PKLDYLLIGGPYP-SFFLNVPDVFANFIRERVDGLEGLFTTCTGAMVAATV-------GILDGKTATTNHQYLELARK----------------QK-PEVNWSS------KQWVADGKFWTAGGAVAGMDMFGHWV----------- +-----------------------TDCFLGDVVKLLEMLTSIEYVTHIYSLYGGSVSSPATA---LM-----------------NME-TQAMQISRPLDIDMLIIAHGSLEAIS-PPPDSTVNWLRTICSQSRCVVALGAGIFLLAAT-------GLLHQRTVTTYSSLVSRLIA---GYP--------------TLRVKK-----SADFQRDGKFYTTSERINIKEMAQLLLL---------- +-----------------------PGCYVGDVIKLLETLHAASLQARVYSLDGAPLRSPAMP---WV-----------------SVQ-THPLDPPGPDAPDTLIIAHGPAQALD-TAATPLLRWLQAVQPRARRVVALGAGVFWLAAA-------HLLDGRQVTTHSALRTLLAL---RFP--------------ALAVQS-----GGSVQIDGPFYTTNERMSASDMALLLLR---------- +-----------------------ENFSLTEVCLIVEMLRI-AFSVAVLSSR--QALVPSGS---FV-----------------QLF-ARATAAHDARLFETVFVAGGAGARAA-SHDADLLSWLRELPGHAL-VMGLAPGAEAILSM-------SGRTGNPVAGYKVLADDSAV----WR--------------AVTCTR-----TTGEGRGTVQYE-----LAVDAVLSMVR---------- +-----------------------PGFPMMAFSSVIEPLRADRYRWVIVGADPGTVEASNGV----------------------VIQPG--FSAADAPKADRIVVCSGGDA-DHVV-ADEAMSWIRKSLRGGAHIGAVADAAFFLARA-------GLLDGHACTLHWTSQAAFTE---AFP--------------DIELR------RDLFVIDRKRFTSAGGVGSLDMMLEIITR--------- +-----------------------------------------------------------------------------------RISKTTTDSEVQPGMLDVMMVPGPDP---RIVSDEDTQSFLKSHAENGVDILSVCTGIFLVAQS-------GILEGLSASGPRALIPRLKK---EFP--------------DTKWVD-----DRRWVVDGNMWSSGGITNGLEMIAAYIR---------- +---ARVALVLSGC-GVY------DGTEIHEASAILVHLSRGGAEVQIFAPDVPQMHIDHTKGQ-PSEGES------RNVTESARIAKITDLANLSAANHDAAIFPGGFGAAKNLKVNKEVERVLKEFHQAGKPIG------------------------------------------------------------------------------------------------------------ +-----------------------------------------------------------------------------------------------SESFDVVFIPPATMGMTVKFDDKVMLNALTLLHHSGATLAANCASVFWLAQA-------GLLDLRSATTHWKLCDKLKE---QYPQI-------------VEVKK-----HQMVVDEGAIITGSGLFAFQDVTLHLI----------- +------------------------------------------------------------------------------------------LDEL-TGSFDVLLLPPATEDIYYLAPLESDLQWMVEQHRQGTLLASACAGAFVLAAT-------GLVQHRSITTHWGLAQHL----------------------------------------------------------------------- +--------------------------------------------------------------------------------------ADYSLEDCP--VTESILIPGGNGAWWKGKKLQPLVNFVKARATETKRIISVCSGATILAAA-------EILNGLSATSNKNLMSGWNA----TPTSRP----------AIDWQY-----DQRWVRALEIWTSSGVSAGIDMTLTMMNT--------- +------------------------------------------------------------------------------------------------EPPAAVLIPGGAGA-QKAARDPLVRAFLTAQVERGIPVAAVGAGVLLLADA-------ALLTDREVGCSADLADTVWG-------AN-----------PSGVR------VNAVVTDGHITTAPGGLGALRATFAALR---------- +------------------------------------------------------------------------------------------------EPPEGVFVPGGVGA-ARMSRDPLVQSFLRAQHARGVPMAASGSGVLALGEA-------GLLEGLVVSTSADLEDTVWG-------YS-----------PSDVL------SGGLSEDSDRISSHGGLGALDAALCLAA---------- +------------------------------------------------------------------------------------------------PEPAALLLPGGPGA-AKASRDPLLRAFLGAHP--ALPTGASGSGLLLLGEA-------GSLRGREIGGSEDLTESLWS-------YE-----------PLDIH------PGRAVTDAQLRTAPGGLGAFEAALHVAA---------- +------------------------------------------------------------------------------------------------PEVCALLLPGGPGA-AKAARDPLLRAFLGTHA--ALPTGASGSGLLLAGEG-------GLLRGREVGGPPELEDSLWN-------YD-----------PASLH------PGEVRRSGPLTSAPGGLGAVRAALAVAA---------- +------------------------------------------------------------------------------------------------PEPAALLLPGGPGA-LKAARDPLLKTFLSAHA--TLPTGASGSGLLLLGEA-------GLLSGREVGGPADLADTLWG-------HG-----------AGDVH------AGGVWTDANLCTTPGGFPALHAALHVAA---------- +------------------------------------------------------------------------------------------------PEPAALLLPGGPGA-QKAARDPLLRAFLTRHA--ALPTGASGSGLLLLGDA-------GTLRGRVVGGPADLTDTLWG-------YA-----------PDEVR------PGEVATDGSLTTTPGGLPALHAALAVAA---------- +------------------------------------------------------------------------------------------------PEPAALLIPGGPGA-AKAARDPLLREFLAGHA--ALPTGASGTGLLLCGAA-------GTLLGRVVGGPADLADTLWG-------YG-----------PADVH------PGEVITDGLLTTAPSGLPALHAALAVAA---------- +------------------------------------------------------------------------------------------------PEVCALLLPGGPGA-ARAARDPLLRAFLSSHA--ALPTGASGSGLLLAGEG-------GLLRGREVGGPPELEDTLWA-------HE-----------PASLH------PGEVRRSGPLTSAPGGVGALQAALAVAG---------- +------------------------------------------------------------------------------------------------PEPAALLIPGGPGA-AKAARDPLLQGFLRAHA--ALTTGTGGSGLLLPGEA-------GTLDGRVVGGPAELADTLWG-------FT-----------PADVR------PGEVVTDGALCSAPAGFAALHAALHVAS---------- +-------------------------------------------------------------------------------------------------------------------------------------MGCVDTGALIFAEA-------GLLDRRPAAAHHEAIVGFRE---SRG--------------EAFFA------DRLFDLDHDRCSSAGGVVTIDMTLAMISHFE------- +-------------------------------------------------------------------------------------------------------------------------------------IAAVGTGCCFLAES-------GLLNGKPATTHWHYFRQFSR---DYP--------------SVKLQ------TKHFLTQAENIYCAASVALSDLTIHFIETIY------- +-------------------------------------------------------------------------------------------------------------------------------------LIGLCTGSFVLARH-------SLMEGRTACVHAYHCDDWKR---LFP--------------RLRFVS-----NSDFLIDKDRITCAGGISVIELAIHLIGMHC------- +---MKSCIVLY------------DGMSMLSFAKIYDFFIANSIDFEVVSLREE-VTCEGLF----------------------KLNSPN-YSQ-SLYGYDIVVFPDGAGA-LNLSYDDIFLSWIKSSN-DARIKIAINRAYLIIKEA-------GLFHRQLFM-------------------------------------------------------------------------------- +---MKCCIVIY------------DKVNLLSFAKIHDFFARKKLDFDVVSLRDS-VVCEHEF----------------------RLFSPR-HSE-SLYGYDIVALPDGMGA-LNLRYDDIFLSWIKSAS-NAKVKLAIDLGALIYAGA-------GFLESKSAV-------------------------------------------------------------------------------- +---MKIGIVLY------------DKVNLLNFAQISDFVRGLGARVKTYALKPE-IVDEVGL----------------------RLHPEI-YAE-SLYGLEAIIVPDGIGA-LSLRYDEIFLSWIKGAL-GAKFKIGLDLGVLILGGA-------GFLKGREAA-------------------------------------------------------------------------------- +---MNIAVVMY------------DKMNLIGFSQILGYLRTFNARIKTCAFKPE-IVDEFGL----------------------KIQPEI-YGE-SLYGADMIVVPDGIGA-LNLRHDEIFLSWIRSGS-SSKIKFGFDLGVLILAGA-------GFLQGRQAT-------------------------------------------------------------------------------- +---MKVGILMF------------DKINLLSFAKIYDFLHKFGFNIKTYALKPE-IVDEFGV----------------------RLHPEI-YAE-SLYGVDILVVPDGVGA-LGLRYDEIFLSWIKSSA-SAKFKIGFDLGVLILGGA-------GFLEDREAC-------------------------------------------------------------------------------- +-----------------------------------------------------------------------------------SIQPQEPFG--NPRRFDYIVVVGGLLD-EVVRSDEQIDEFLQRAAVAGVPLVGLCTGTFTLHRA-------GLMDGYRGCVSWFHHQDF------------------LSQFGLKPVS-----DQIFVVDRDRLTCSGGASTAHLAA-------------- +---------------------------------------------------------------------------------------------------------------------------------EAKWVMSVCAGSAILALA-------GILHGKRATPNNFLYKTITN---VY------------GRDGITWLP-----KARWVADGNVWASSGITACMEVNILN------------ +----------------------------------------------------------------------------------------ATLDA--LERADAIVVPGGSGAAN-AARQPSLSTPLARAHARGAAIYAVCSGALVVAAS-------GVANGRRLAIHSDKRQAL----------------------------------------------------------------------- +----------------------------------------------------------------------------------------APLDT--LDHAHAIVVPGGRGAAA-AARHSSLATLLARAHMRGAAIYVVCSGALLVAAA-------GIANGRRLAIHHDKQQWL----------------------------------------------------------------------- +------------------------------------------------------------------------------------WLPNVTYDDC-PRDLDIVI-TGGPFPSH---RPAAADRFMKEAFPKTRVWMTTCTGSMWLASS-------GALDGKKATTNRNFLAGAKQ---MYP--------------AVEWVE-----QRWVVQDGEVWTAGGAGAGIDMMVDYCL---------- +-----------------------------------------------------------------------------------NIQPDISLDECTLESKDLLVLPGGTT--WREDIHQPILKRIGEALKLGTIVAAICGATEALANM-------GYLDSRKHTSND----------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------------------------------VIAFVARHELICPICSAAARVLGAH------GLLKGRRYVCSGDLWK-------AVP--------------EGVYV------DAPVVEDGNLISGKGLGHVFDFALT------------- +-----VLFALH------------PNFNITDFAGPLEVFATANFECTVAAAEPK-VMSEQGVF----------------------IGSQISYKEARLNDFDVLVVVGGGTDAEPLQLIDAYSELQQKDTIRERTLLSICTGSLFLAKQ-------GILAGLSATTHPDFLTTF----------------------------------------------------------------------- +-------------------------------------------------------------------------------------------DDVLIGTPDIVVVPGGRDDGPDPAYPSELPDRLEQLAEAGATVVGIGSGALALGEA-------GLLTDRTATTAPAFRD-------------------ELTTDAGTVV------DEDIVEGDGVLTAAGPNTALEVGRRLGVQHCE------ +----------------------------MEVVITIDELRRAGVNVTVLPVRKRQVDACRGVD----------------------IVADAPISDCAGADFDLILLPGGMPGAATLGAGDILESMVKKHADDGQLYAIFRVAPAVALGS------WGLMHG------------------------------------------------------------------------------------ +ASRREVLVFRHLAF-------EDLGTWE-------ETFSQLGFRVAYVDMGADP------------------------------------LDENRVMNAALLIVLGGPIGVHDYPFLADEESAIKRRMSQESPIIGICLGAQLMALA------------------------------------------------------------------------------------------------ +-MTAHAIILQHVLA-------EDAGLLT-------PILHDYGYTVTMIETPIHS------------------------------------VTTTQALDADLLIALGGPIGVEDHPYLHDELDALGTRMADNAPTLGICLGAQLMAHA------------------------------------------------------------------------------------------------ +-------------------------------------MRELGYRIEYVDAGFGR------------------------------------VDAGAVSEADLLVVLGGPIGVGDYPYLTDEIKAIADRIALGRLTFGVCLGAQLIAAA------------------------------------------------------------------------------------------------ +-MSLNAVAIRHVPF-------EDLGILA-------PILAERGYSVQYLDAGIDA------------------------------------IDAATLGNADLVVVLGGPIGVYEYPFLELELRAIAHRLRLDKPTLGICLGAQLMAAA------------------------------------------------------------------------------------------------ +-MSLTALAIRHVPF-------EDLGVLA-------PVLAERGYSVRYLEAGVDT------------------------------------IDAATLGNADLVVILGGPIGVYEYPFLEQELRAIAHRLRQDKPTLGICLGAQLMAAA------------------------------------------------------------------------------------------------ +-MSLSALAIRHVPF-------EDLGILA-------PVLADRGYSVRYLEAGVDA------------------------------------IDSATVANADLVVILGGPIGVYEYPFLEPELRAIAQRLRQDKPTLGICLGAQLMAAA------------------------------------------------------------------------------------------------ +--MKTAWAIRHLRF-------EDLGLLD-------PLLRERGYDIHYHDASADL------------------------------------PTPMGCDSADLLVVLGGPMTADDHANLRDEVAILRQRRERDLPTLGICLGAQMMALA------------------------------------------------------------------------------------------------ +--MKTAVAFRHVPF-------EDLGTLA-------DTLHSLGYECRYIDTPVES------------------------------------FAHLDPQAADLLVVLGGPIGAYQYPFLSEELRHIRERLAHGKPVLGICLGAQLMARA------------------------------------------------------------------------------------------------ +--MKTAIAIRHVAF-------EDLGTLR-------RVLEMRGYRIEYREAGVDR------------------------------------LDTAALDQADLLVALGGPIGANDYPFLEQELRLLQARLRQRRPTLGVCLGAQLMARA------------------------------------------------------------------------------------------------ +--MTRALVIRHVAF-------EDLGIAA-------PILAGHGLEVVYWDAGGDA------------------------------------PSVGPADDADLLVVLGGPIGVGDYPVLTAELDAVRRRLAIGGPTLGICLGAQLIATA------------------------------------------------------------------------------------------------ +----MIDVFRHVKF-------EDLGSFA-------AVLERLQIDFRYIDVPVLK------------------------------------DTDLDPLSRRPLIVLGGPMSVHDYPWLVSETEFLGRRIAEGLPTLGICLGAQLIAKA------------------------------------------------------------------------------------------------ +PWERTALAFRHVHF-------EDLGNIE-------PLLRERGYRVQYVDLGIEA------------------------------------IDIERVDDADLLVVLGGPIGVHDYPMLHASKEAVSHRLRSGRPLLGICLGAQLIAEA------------------------------------------------------------------------------------------------ +MPERTALAFRHVHF-------EDLGIIE-------PLLRERGYRVEYVDLGVEA------------------------------------IDIERVDDADLMIVLGGPIGVNDYPFLHASKEAVAHRVRSARPLLGVCLGAQLIAEA------------------------------------------------------------------------------------------------ +PRERTALAFRHVHF-------EDLGILG-------PLLRERGFRVEYVDLGTEA------------------------------------IDIERVDDADLMIVLGGPIGVHDYPLLHASKEAVAHRLRSGRPLLGVCLGAQLIAEA------------------------------------------------------------------------------------------------ +DQRARVLEIRHADS-------EPPGFYG-------PPLIDLA-DVTILRIWREP------------------------------------VPT-DLTGFDAVVTLGGAMGVGDIPWIADEIALLRRALDLGIPIWGVCLGAQILAAA------------------------------------------------------------------------------------------------ +IDPVRVLEIRHAET-------EPPGSYG-------PALDELA-DVTTLRIWRED------------------------------------VPD-DLSDVEAIVTLGGAMGVDDIGWIDHEIVLLRRALELGIPVWGVCLGSQMLAAA------------------------------------------------------------------------------------------------ +PERLRVLEIRHAES-------EPPGAYG-------PALYDTT-ETTTLRIWRES------------------------------------ASV-DLMGFDAIVVLGGAMGVGDIPWIGDELDLLRRARDRGMPIWGVCLGAQMLAAA------------------------------------------------------------------------------------------------ +PQRPRVLEIRHAES-------EPPGAYG-------PALDDTA-ETTTLRIWRDP------------------------------------ASI-DLTDFDAIVVLGGAMGVGDIPWIGDELDLLRRARDRGMPIWGVCLGAQMLAAA------------------------------------------------------------------------------------------------ +PDRPTILELRHVEC-------ESPGSYS-------AGLAPVA-DMVTVRSWREP------------------------------------VPT-DPSPYAAILVMGGPMGADDIPWIADELALLRRAVAADIPIWGVCLGSQLLAHA------------------------------------------------------------------------------------------------ +---MHFLELRHAQC-------EPPAAYS-------PVLESYG-DVQTVLLGTDP------------------------------------LPA-H-RRFDAVIVMGGPMGVGDVEWLASEIDYIRDLVENDVPVWGVCLGSQLLAAA------------------------------------------------------------------------------------------------ +---MRFLELRHAQC-------EPPAAYS-------PVLDTYG-DVQTVLLGTDP------------------------------------LPT-H-VEFDAVIVMGGPMGVGDIEWLASEIAYIRALVDADVPVWGVCLGSQLLAAA------------------------------------------------------------------------------------------------ +-MTPVVLELRHVEC-------EGPAAYL-------PVLEQYA-QVHTVRLWRDP------------------------------------VPA-A-LDYAAVVVMGGPMGVADVPWLGEEIAYLRAAVAAGIPVWGVCLGAQLLAAA------------------------------------------------------------------------------------------------ +MTRPTILELRHAEC-------ESPGTYG-------AGLAGLA-DVRTVRTWREE------------------------------------LPT-DPRDFAGILVMGGPMGANDLPWIDTEIAFLTAAVAADVPIWGVCLGSQLLARA------------------------------------------------------------------------------------------------ +NPVRKVLVIQHVEC-------EPPAAFE-------DVLVERGIGIDRIELDRGD------------------------------------ALP-DWLLYDAIIVMGGPMGAVDFPWLLDERKFIEEAVSAGTPYWGVCLGAQLLAAS------------------------------------------------------------------------------------------------ +----MLTVIQNDPD-------VPLGSYA-------DQLTASGEEFNIVELYAER------------------------------------LSG-DLLASNGIIILGGTMGVYDYPYLLDLKNYIRQGISRRIPMLGICLGGQLMAEA------------------------------------------------------------------------------------------------ +AVPIRLLELRHAEI-------ESLGTYA-------DGLPPRA-DLHTVRAWRDP------------------------------------LPA-DPAAFDGIVAMGGPMGANDHPWIDAEITFLRHALAAGVPVFGVCLGSQLLAAA------------------------------------------------------------------------------------------------ +MTTLRLLEIRHAEC-------ESLGTYA-------GGLPHDA-EVTTLRAERDT------------------------------------FPD-DPASFDAIAVMGGGMGANDYPWIDDEIDFLRRALSKDVPIWGVCLGSQLLASA------------------------------------------------------------------------------------------------ +ASPIRLLELRHAEI-------ESLGTYA-------DGLPATT-ELHTVRTWREP------------------------------------LPD-DPTVFDGIVAMGGPMGANDHPWIDAEITFLHRALAADVPVFGICLGSQLLAAA------------------------------------------------------------------------------------------------ +-MTKTTLVLRHVHF-------EDLGSFA-------GPLQDAGYDIRYSEVDDPD------------------------------------FCAGDPLQPDLLVVLGGPVGVYEYPFIAVEREFIRARLREGRPTLGVCLGAQLIASA------------------------------------------------------------------------------------------------ +MAGKAALVLRHVHF-------EDLGSFG-------EPLAGAGYEVLYQDVGESS------------------------------------FLSGDPSAPDLLVVLGGPIAVYEYPFLDDELAFIGRRLDTGRPILGVCLGAQLIARS------------------------------------------------------------------------------------------------ +-MSKSALILHHLAF-------EDLGSFG-------PVLEEEGYRLNHVEAGIDA------------------------------------LP--DSRGPDLVVVLGGPIGVNDYPCMKSERDWLAPRLAARRPTLGICLGAQLMAAA------------------------------------------------------------------------------------------------ +--MKSALILRHLAF-------EDLGSFA-------PVLTDAGYQLQDIEAAVDP------------------------------------LP--DPLEPDLVVMLGGPIGVNDYPCMTEERDLLAMRLAADRPTLGICLGAQLMAAA------------------------------------------------------------------------------------------------ +--MKSALILRHMAF-------EDLGSFA-------PVLRDAGYQLQDIEAAVDP------------------------------------LP--DPLEPDLVVVLGGPIGVNGYPCMTEERNWLAMRLAADRPTLGLCLGAQLMAAA------------------------------------------------------------------------------------------------ +-MRRRALVIQHDPT-------IHLGNLE-------QVLLEANYDLTVVDA-RGY------------------------------------AFDERPEDVDLVVVLGNDHGVYEHPYIAREEAWLAARAAHERPTLGVCFGAQILASA------------------------------------------------------------------------------------------------ +------MVLRHERI-------AHLGNLE-------PVLVAEGFDVQYVDVAEGD------------------------------------ELPPNASSADLLIVLGASAGVYEYPFIAAELAFVRSRLDAKRPTLGVCFGSQVMAAS------------------------------------------------------------------------------------------------ +RMNRTALAIRHVAF-------EDLGIIE-------PLLTERGYTVRYLEAGVDA------------------------------------IDRATVTAADLLVVLGGPIGVYEYPFLAEEKAAIAARLKQDKPTLGICLGAQLMAEA------------------------------------------------------------------------------------------------ +EVALKALFIEHDHI-------SPPGPVA-------ERLRYHGFQISEEVVVSQA-------------------------NFRSPNVDFQFPD---AQDFDLIIPLGAPWGAWDGKWLVPELEWIRSIVESGKPVLGICFGGQLIARA------------------------------------------------------------------------------------------------ +HKELKAVFIRHVAF-------EGPGILS-------RILDSTGFSQTMVD----------------------------------ACDGGLS-R---QDPGDLLVVLGGPIGAYDYPFLVDEMKLIERSLKKGVPVIGICLGSQLAARV------------------------------------------------------------------------------------------------ +MTARPLLVLQHAPW-------EGPALVA-------RALAARAPGVELVTRSVLD-----------------------------HAAPDLP-A---PADLAGLVVLGGPMGADDHPGLAAERSLLARAVDADLPVLGVCLGMQLLARA------------------------------------------------------------------------------------------------ +PK--TIYAIQHLAF-------EDLGSLE-------DVFYQLGFRVRYFE----------------------------------AGVDDLTPA---FTHDGLTIILGGPIGVYEYPFLKDEIALLKQRLAADKPTLGICLGAQLIAHA------------------------------------------------------------------------------------------------ +--MSEVLIIQHQAM-------EGPGTIE-------EEIVKAGHKVRKVRI---D-----------------------------QGH-PVPSE---AGSLAGIVVMGGTMSVADLKHLKEEIGLLKQFVQAEKPVMGICLGAQLLAAA------------------------------------------------------------------------------------------------ +ESRLPVLIVLHQES-------STPGRVG-------NALRALGHRLDIRRP---------------------------------RFGDPLPET---LDQHAGAVVFGGPMSANDY--IRREIDWIEIPLREQRPFLGICLGAQMLARQ------------------------------------------------------------------------------------------------ +RDRRPILIVLHQER-------SSPGRVG-------QLLVEKGYHLDIRRP---------------------------------VLGEPLPTT---LEDHAGAVVFGGPMSANDF--IKKEIDWIEIPLREKRPYLGICLGAQMLVHH------------------------------------------------------------------------------------------------ +---MRLHFIVHEDF-------EAPGAYE-------IWGKMNNFKITYSRV---------------------------------YLNEVLPTS---VEDIDFLIVMGGPQCPDTHFNSLAEQAMIKKAIEANKVVIGVCLGSQLIGEA------------------------------------------------------------------------------------------------ +---MRVHFIVHESF-------EAPGAYE-------TWAINQGHDVTYSRV---------------------------------YAGDRLPDD---AVGIDFLIVMGGPQDPDTHFNAKAEQALIASAVKTGKAVIGICLGSQLIGEA------------------------------------------------------------------------------------------------ +-TMPTALVLVY------------PSVNTLDTNGPIGVLFQGGFSTLIAARDEF-----TTSQENV------------------TIKRDLSIAEARLTEFDLLIVPGARPN-NILPHLHELLELISAFAKLGRVLFSVCSGSYLLAAT-------GVLDGLTATSHRLGLGALRKLCDEYKSRTP-------GAKGTEVVPESPTGTVYYVDAGRIVTSGTITTGIDAAL-------------- +------------------------------------------------------------------------------------------------KPIDVLIIPGGPGTRLNVSNTQEVQDFLTAAAPVRHSIITVCTGSHILSQT-------GLIDGRQATTNSARFD-------------------DVTKQNVNWQR-----NRRWLRDIEIWSSAGITAGIDVMLE------------- +-----------------------DDFNSMDVFGPVEVFGKEHFHINYWSVSGNIINSSQGA----------------------KLWTEPVDEEM---ENGILLIPGGRGARRVIHHERETIELLQKLVSNADTCLMVADGSGFLAQT-------GVLYRRNIAEYKMNENWK-----------------RMFTAAVYWIP-----NVSWVADGKFYSSSSSLYGIDMAL-------------- +----KVLITLH------------DDMDTMDAVGPLEVFSWAAFRTIFAGPQEHV----TTLQGA-------------------SLRAHITYDEARLSEIDVLVISGGSH-EDVVKNKKQPLALIKAFAELERSLMSVCTGSLFLAEA-------GILSGLTATTHPDFITKF----------------------------------------------------------------------- +---------------------------------------------------------------------------------GLRLQPDITYDD--EQLFDILILPPMWGNLQSIRRDPKIIPWLVKQHQKGAKLVATGTGVLWLAET-------GLLDHEVATTHWYYYDNFAA---RYP--------------NITLNR-----QASITAANNLFCTTSINSQSEMIL-------------- +---------------------------------------------------------------------------------------------------------------------------MNELHKQNKWIADICAGTSLLHAA-------GVLNKKKFSTSLTSGEKY-----------------LAHLHEWEYKQ-----NKDVTVDGKIITAVGSA-YVEFA--------------- +---------------------------------------------------------------------------------------------------------------------------VQELHAEGKWIAGICAGTALLHAA-------EVLRNTKFSTSLISEVEH-----------------LVHLHEWEHKQ-----SADVTVDGQIITAVGSA-YVEFA--------------- +-----------------------DSVLMTEVTAPIDVFSKPNFNVVTIAQSHQPVPMESGL----------------------RVVPDYSFDDCP--DLNVLVVSSSYD-METVVATDEIVEFVKTKGKTTDFTMSNCAGAHLIGAS-------GVAKGRKIVTYIGGGDLLQQ---TYP--------------SLSVQDDS---QVSFVKDGKMISSNGNLASYISALE------------- +MASKRALVILA------------KGAEEMETVIPVDVMRRAGIKVTVAGLAGKPVQCSRDVV----------------------ICPDASLEDAK-------------------KESAAVKEILKEQEKRKGLIAAICA-------------------------------------------------------------------------------------------------------- +-----------------------PGFQLLDACGPLDLLTEHELSLSIWSTTLDPVPTKHPSVFD------------ENPRFSESIKPTHTFAQISQVETDVVIIPGGTGTRIPKDSILPTLEFLKSYLSSGHSIFTICTGSRLLAQT-------GYLDTLKATTNKRAFD------------------------------------------------------------------------- +--------------------------------------------------------------------------------------------------------------------------MLASIAERGIPLGGICTGAYALMSS-------QLLDGYRCSLHWENRAALQD---------PFPL--------AQFA------DELFCVDRDRLTCTGGTAPIDMML-------------- +--ARKIALLVA------------PGVMGESMAQVQAALLAEGAVPRLVAPHIGSVATAEGK----------------------TLDADASLENEPGFLFDALVLPDGQAAVDALAKDGHTMEFIKDQYRHGKTILALGAASALLEKA-------GV--------------------------------------------------------------------------------------- +--TRLVGVLVA------------DGFDAEDLSATRAAIEKAGGQMVVIAKRLGTVKGSD------------------------PVMVDKSSLTTASVEYDAVFVPGGAA--AVLKKDADAMQFIQEAYRHCKAIGVTREASELLDAG-------GI--------------------------------------------------------------------------------------- +--SRSVAILVA------------DGVDGPSTAAVQAALRAAGATVHLIAPRLGMVKPAKGE----------------------PFQATGTLENSAPVLFDGVVLPDGAAGVKTLGGCVEVMDFIAAQFRHGKTLLAIGASGALLERA-------GA--------------------------------------------------------------------------------------- +--GLKIAILAA------------HGMLGQSAAAVHAELTALGATPCFVAPHIGEVQTSDQV----------------------PVVADASLENEPGFLFDALVLPEGEQAVQNLASDPHTLDFIKDTYRHGKTLLSLGASQALLAAA-------GV--------------------------------------------------------------------------------------- +--GRKVAILVA------------NGVEAESLLKLHSKLFELGAVPRFVAPHIGPLTTSKGA----------------------VIDADASLENEPGFLFDALVLPDGEMGVKELARDGHTLEFIKDQYRHCKPIMVMTASTVLMHMA-------QI--------------------------------------------------------------------------------------- +--ARKIAVLVA------------DGVDGTVVAQVVQTLVDAGAVPRLVAPHVGTIVTADGG----------------------SLDADASLENEPGFLFDAIVLPDGAQAVTALAADGRTMEFVKDQYRHCKTLLVFAASQALLDAA-------GI--------------------------------------------------------------------------------------- +--GRKVAILVA------------DGASPAGLHALQAALLEQGAVGRFVGPHIGPVALADGT----------------------EVDADASLENSPGFLFDGLVLPDGEAAVTLLSRDGHAAEFVRDQFRHCKPILVLGASQTLLVES-------GI--------------------------------------------------------------------------------------- +--GRKVAILVA------------DGIVGKSAVALHEALFTQGAVPRFVAPRIGPVKTSDGV----------------------AINADASLENEPGFLFDALALPDGEAGVQALARDGHTAEFIKDQHRHCKTILVMPASAALMLKA-------QI--------------------------------------------------------------------------------------- +--GRKVAILVA------------PGVEGASVSAVQAALVEQGAVARLVGTRIGRMPTQEGD----------------------ALDADASLENEPGFLFDALVLPDGAQAVAALAQDGHTMEFIKDQFRHCKAILVLGASKELLVKA-------GV--------------------------------------------------------------------------------------- +--SRKIAILVA------------DGVEAGSVVALQAALLQAGAVPRLVAPRLGSVKAGGAA----------------------MLEPDASMENSPGFLFDALVLPDGEAAAQALAADGHTMEFIKDQYRHCKTILALGASQALLSEA-------GI--------------------------------------------------------------------------------------- +--GRKVAIVVA------------PGVEADFVREAQARLLERGAVARIVGPRIGPIAAASGV----------------------ALDADASMENEPGFLFDALILADGAAAIAALAQDGHTMEFVKDQFRHCKPILAVGEARRLLLQA-------GL--------------------------------------------------------------------------------------- +--ARKIALLIA------------PGILGESMAQVQAALLAEGAVPRLVAPRIGSVATAEGD----------------------VLEADASLENEPGFLFDALVLPDGQAGVDALSLDGHTMEFIKDQYRHCKTILVLGASSALLEKA-------GV--------------------------------------------------------------------------------------- +--GRKVAVLVA------------PGVEGKSVALAQAALLEQGAIARLVGTRIGRMPTSAGD----------------------ALDADASLENEPGFLFDALILPDGQEAVAALAQDGHTMEFIRDQFRHCKTILALGASRQLMVKA-------GL--------------------------------------------------------------------------------------- +--GRRIALLVA------------DGVSGAAAGALYDALLTAGAVPRYVGERLGVVRTAEGD----------------------ELPVEVTFETAPSVLFDAAALPTGANA-AALARDGLAVEFVQLQYRHCKPLLVPASAAQLAAAA-------GV--------------------------------------------------------------------------------------- +--TRKIAVLAA------------DGFSK-ELSLWLQTLKSKGTMPEIVSDHHGKIVGED------------------------ELEVKHTLLTADSVLFDAVLIASKEG--V-TF-AKEAPDFITEAFLHYKPIGALAEGNILLESL-------VN--------------------------------------------------------------------------------------- +--TKKVGIIVD------------TNS---NLEDLVMPLEKEGVVVELISDKQGRIG---------------------------QREIDHTLETASPVLYDGLIIAATFE--VPN---RKVQTFADEIFNHYKALGYVSVES--MDKD------------------------------------------------------------------------------------------------ +--TRTVGVIVM------------PDVAEQTLKETKSKLEEKGLQVSFISDKIYKIG---------------------------NTTLDATFDTVHSVLFDSMIVISGQK--P-A----PAIENLEITYKHKKAIGYGIDSASIFDVL-------SF--------------------------------------------------------------------------------------- +--TRKVGVLVD------------HGFNDAEVMKVLEELEGKGVNYEVVSETQGTLKGSG------------------------ELEVDHTFTTTDPVLYDAIYAVGGPD--K-KF-AKEAARYVGEAFDHYKPIGATHDGQKWLQTA-------GI--------------------------------------------------------------------------------------- +--TRKIGVIIG------------DRFDEDLVMPVLDTLMRAGIQPEIISDKLGFIKGSK------------------------ELEVIHTLSTTDSVLFDAIYAAGGNS--K-KF-HKDTAQFLNQAYSHFKPIAVTTENAKLLETA-------EH--------------------------------------------------------------------------------------- +--TRKVGVILA------------NGFSDQEIVEILDQLTASNIQYEIISDHQGKVTGEN------------------------DLMVNHTFTTTNAVLYDAIYAGGGKE--Q-AF-DRSTTEYLEEAFRHYKALGATQEGKEWLKAS-------NI--------------------------------------------------------------------------------------- +--TRKIAVLLD------------EGYNGEVVNNIVQQLKKQGMEPEIIASKLGKLKTDK------------------------QFEVDNTFLTVDSVLYDAVYVAGGAG--K-TF-QDKAGYFMKEAYSHFKPIGATHDGEELLKHL-------GI--------------------------------------------------------------------------------------- +--TLTVAVIVT------------KGFNGPDVKYVLDHLVAAGIQPKIISETIGEVSGTN------------------------NLNAEFTFLTAKSVQFDSVYIVRASS--P-TF-NKQIAHFTDEAFSHYKPIGASPGLNQWLERN-------NI--------------------------------------------------------------------------------------- +--TRKVAVILA------------KGFNGPEVKYVLKQLKDADLTVEIISENQGNVLGTN------------------------ILKADHTFQTAKSVMYDSVYIVNGSQ--K-RF-NKDAVYFIDEAFSHYKPIGASHEGIQYLTVN-------HF--------------------------------------------------------------------------------------- +--TRKIAVLLA------------EGFNGEEVQGVLDGIDKAGADAEIFSTKLGKIKADN------------------------TVEADHTFLTGDSVLFDAVYVVGGPD--E-SY-KMKAKYFTKEAYMHFKPVGATHDGKDWLEEA-------GM--------------------------------------------------------------------------------------- +--SLRVGVLIG------------NGFKGEEVRKVIDTLQQNGVFVEVISEKLGTVTGAD------------------------KIKVTKTFLSTHSVLFDSFYVVGGSS---QWEFDRYITEFINDAYKHYKPMGIATTAATYIEPD-------NL--------------------------------------------------------------------------------------- +--TRKTAVIIS------------DGFNGAEVKKVIENLQAAKVQVAILSDRLGSITADD------------------------TLKAKHTFLTDSSVAFDAVYIAGGMK--K-MF-EKKAKMFMQEAFDHFKPIAVSNEGEQWFKEK-------QL--------------------------------------------------------------------------------------- +--TLRVGVLIA------------DGFDGDETKYVLSELEEAGLELVFVGERLGDVEGSD------------------------KYSIDETFLTGSPLLYDGLYVIGGSD---RY-FMRKTRNFVRDTYNHFKPIGATEEGAVIIEQM-------NI--------------------------------------------------------------------------------------- +--TLKVAIIVG------------NGYGGNALESLLESLKEVELKPYIISERLGEITADN------------------------TLNVDATFLTTSPVLYDGLLVVGGDH--D--QFAYEAGNFITEQFNHYKPIGGMEEGATLIQQL-------GI--------------------------------------------------------------------------------------- +--TLRVGVFLA------------EGFDGPSVKKLLDTLVKAKLQMVIVHDRLGTVTGTE------------------------QYEVDDSFLTGSSLTYDGVLIVGSGN---PY-FTYEVQKYTVNIYNHFKPIATMQNGEAVLEPL-------NL--------------------------------------------------------------------------------------- +--TLKVAVFLA------------EGFPGKEVDALLKQWKKAGMHPVIVSNKLGEVKSSE------------------------RFDVDQNFLTGSPLSYEGAYLVGGTG---DY-FHHQARTFIMNMYNHFKPIGAREESAHLLKEM-------GI--------------------------------------------------------------------------------------- +--TRKVAVLIA------------DQFDETILEPIIKTSLDAGMSIHIISEKFGTLTGKG------------------------TVVVDETFLTVHSVLYDALYVAGGQA--QNKF-EKDVADFVNEAYMHYKPIGIAPNAKALFEKT-------QA--------------------------------------------------------------------------------------- +--SRRISVIIE------------KGVDYDDVINFKDDMEKRGAMVMLVSSTLAQVECSG------------------------MLSPKGTIIGNPSIFFDAVYVPKTEE--KILSDDGNFLHYILEAFKHLKTIAFGGSVSVIKELL-------RL--------------------------------------------------------------------------------------- +--TRKVGILAA------------DGYDDSTIEPIMQAFKQAGVHAEVISGHLGMITSVN------------------------QQEVKHSFLTAESVLFDALYVACGEK--EQLKN-NKAVEFLKDAFKHFKTIGAAGKGAELLITA-------GI--------------------------------------------------------------------------------------- +--TRKVAILAG------------DGFDQHAV-TLMNALTEAGAMAEVVSDHLGPVAGQG------------------------SVEAMHTFLTSDSLLFDAIYVAGGEH--QALAD-PNAAEFIKEAYRHYKPIGAVNEGVAFLVKG-------LG--------------------------------------------------------------------------------------- +--GRKLGVLVT------------DGTDAAVLEAVRAAVTDVGAVLETIAPVVGGVTLSD------------------------VLAADQMVDGGPSVLYDAVVLLPGAK--AALAARSTAKDFVSDAFAHHKFLGYNSASTPLLAAA-------GV--------------------------------------------------------------------------------------- +--GRKLGVLVT------------SGSDKAVVRAVAAAFEGVGAVVEYVAPAIGPVKLKG------------------------TITPDHAIDGGPSVLFDAVALLPSAD--TDLAGRASARDFVADAFAHHKLVGVGAHAEALLAAA-------GV--------------------------------------------------------------------------------------- +--GRKIGVLAA------------NGSNAQVLDAIRQATEQEGATLELVAPTVGGFEASS------------------------WMEADHMIDGGPSVLFDAVALVLSEE--DRLTREAAARDFVADAFAHCKFIGFTAGAMPLLAKA-------GI--------------------------------------------------------------------------------------- +--GRKVAVLVD------------KGVSAEQLTIIQETLMDEEAIVEVVAPTAGTVQGGD------------------------LVPVTRAAPNAPSVVYDAVMVPGGAD--SALQASGLFRHFLNEAFLHGKPIAAIGTGEQVLAAA-------NL--------------------------------------------------------------------------------------- +--GRKVGIFLQ------------DGFDTAPVLALQSALKSEGVMAMIVGPRKGSVQG--ST----------------------SLSTQFTFETCRSTHFDATYVAGGSG----L-NTGRLIHAVREAYMHQKPIAVSGSAVEWLQRV-------VL--------------------------------------------------------------------------------------- +--SRKVALVAT------------PGADTRLIERVRRALTDARAVPVLVAPTLARI-----G----------------------ELTPEATLAGMPSVMFDAVFVCGGDG--RDLVHSSDARHFLQEAFKHLKAIAAVGSGRQLLGAA-------HL--------------------------------------------------------------------------------------- +--TRKVAVLLE------------SGFDKAQFDALTATLIAAGACFDVVSCKLGPVTAGD------------------------RVEGNQTYATTASVFYDAVYIPGGSH--EALKGSADVKGFLLDTFNHYKTIGLSGEASALLGLL-------PS--------------------------------------------------------------------------------------- +--TRQVAVLTD------------HGFSDEKVKQVLDACKQAGVRADIISPALGTVKGEN------------------------ELEASATFLTADSVLYDAVFIPGGKQ--DSLKAQKSARDFVNEAFSHYKAIGASGEGKELLALA-------AG--------------------------------------------------------------------------------------- +--GRKVAVLIH------------NLVKSDALEAMKNWAIKEGVTLHLLAPSLAPVKDHQDN----------------------IITADGMQMAEPSIAYDAVIIPDGDN--NAVMQDGVTRHYLLEAYKHLKPIAFLGNKSDLLEPL-------GL--------------------------------------------------------------------------------------- +--GKKIAALVF------------DGLSAKAIRPLLDWAQQHSIALQLLGPTSAPVKTSEGK----------------------SLAVDGSIKGEPSILFDAAIVPDIPT--TALLDNGQAVHFILETFKHLKPLALTGPGASLIKAL-------HL--------------------------------------------------------------------------------------- +--SRKVAIIAA------------PGFDGKQLAAMQEALVAAGAVVEVVSMLLGHIESAD------------------------MVPVKKNYITSASVLYDGVYIPGGQA--SMLAFSGKVKNFISEMYRHCKAIAATGEAVGLLESY-------KL--------------------------------------------------------------------------------------- +--GRRVAILLT------------PGCKADEVGSLKKMLEAAGAVAKLLAPSAAALKDSDGQ----------------------PMQPDGSFASEPSITVDAVFVPGGEY--KTLQDDGVAKHYLLEAYKHLKPVALSGDAAQLAAML-------GL--------------------------------------------------------------------------------------- +--SRKVAILIG------------DGVKQADIDALTAELDKQGAQFKLLAPSAAPVKSDAGK----------------------QLVPNDSMQGLPSVAFDAVWVPGGTS--KALEGDGVALHYLLEAYKHLKAIGLCGESADLLKLL-------RL--------------------------------------------------------------------------------------- +--TRKVAILIE------------NGFNFNEVSQVMTGLSAAGVHADLISKNLGMITSVE------------------------KLEANKSYATSGAIMYDALYIPGGKG--DLLMTHKEAKDFINDAFVHAKPIGATNEGVDLLAST-------DA--------------------------------------------------------------------------------------- +--TRKVAILIE------------NGFNMDDVVQVTTQLESAGLHADIISKNQGMITSAG------------------------QIEAVKSYATASSIMYDALYIPGGKQ--DQLMTHQDAKTFVIDAFTHAKTIGAANSAVDLLMTS-------DI--------------------------------------------------------------------------------------- +--TRKIAVLVT------------DGIDAEQVTSVRERLAAEGAIVEALAPVDGEVRGAD------------------------LYTVDRALPTVASVLYDAVLLPGGPA--PPAAADQDAMRFVRDAYRHGKPIGALGSGVGILSSL-------EP--------------------------------------------------------------------------------------- +--TRKVAILAA------------DGVDVDGLKAMKEGLEAAGALTKIISVRLGGLVAQG------------------------GLPIDATPKTMPSVMFDAVFVPCGPD--EVLKANGDMLHFVMEAYKHCKPIAAAGYGVDLLRMT-------GV--------------------------------------------------------------------------------------- +--TRKIAVLVS------------DGFSMSDYEKMTKSLEKEGATLAIIAPHGGKVTCDK------------------------SHPVDAAINTTESVLYDAVYIPGGKK--DALIKEAKFSKFLNEAFKHCKAIAADNEGENLIDNT-------FI--------------------------------------------------------------------------------------- +--SRQIAFLVA------------PGFDHQNHMRMKDELERQNAVVHLIAPTGGEITCNA------------------------QHKIDATLLTTESVLYDALFIPGGQQ--QILSKQGKAIKFINETLKHCKAIAANNEAESLLEMT-------YV--------------------------------------------------------------------------------------- +--TRQIAVLVD------------NGFDMDGFGKMQAALLAEKAIVKLIAPKGGVITCSK------------------------EHKVDAALPTTESVLFDAVYIPCGKE--DSLAKQGKVFKFINEAVKHCKALAFEGRAKELFEKS-------AA--------------------------------------------------------------------------------------- +--TRKVAILAA------------KGADVASIKAIKDALTAEGAHAKVVAPQLGTLG----E----------------------GVEVDATILALPSIMFDGVVVAGGAA--KLLSESGDARHYVLEAFKHLKAIGAVGDGEDVLAAA-------HL--------------------------------------------------------------------------------------- +--YRKVAILVA------------DGVDAEQVEAAKQKLSAEGAEGLVIAPTMAPVKGANGQ----------------------TLTPDAMLNGLPSVAVDAVIVAGGDE--AALSDSGLGRYYVQEAYKHLKVIAAVGEGKALLDAA-------NV--------------------------------------------------------------------------------------- +--HRKVAILAA------------DGVDAGEVQDIKQRLTEGGATPLVIAPTMAPVTAAN------------------------TIESDGMLNGLPSVTVDGVIVAGGQT--DRLTQSGLAIYYLQEAFKHLKPIAIISEAEELLARA-------SF--------------------------------------------------------------------------------------- +--TRKIGVLVA------------DGVDADELMALRKELEAGGAQLKVIAKRLGTVKASN------------------------DVPVDKSAMTTASVEYDGVFIPGGAA--ATLKKDGESRHFVQEAYLHCKTVGASKDAEELLKAC-------EI--------------------------------------------------------------------------------------- +--TRKIAALVS------------DGFAGKELEGVRKALQERGATLELVGPTLSPVTSQE------------------------EERPLRTFSTASSVMYDAVYVPGGAK--AALRRVPLAVDFVREAYVHCKALALSADAVGLLDAA-------GV--------------------------------------------------------------------------------------- +--TLIVGVLAS------------TASKNSLAQALKDAFKT----REVNV-----IVA--SL----------------------ATGVDQTYDAADAVSFDGIVVADGVE----F-QPGRPSQIVNDGYNWGKPMGFLGSAKRAVKAT-------SV--------------------------------------------------------------------------------------- +--TLVVGVLTS------------THSSSSLAESLKNEFKS----SNVTV-----VTG--TL----------------------AEGIDQTYSAADAVAFDGIVVTDGAE----Y-PPGRPAQIVRDGYNWGKPLGFLGNAANVIQAA-------GA--------------------------------------------------------------------------------------- +--ARRIAILTA------------DGVNDEAFTKVKKELCDMGAMVSVIAPHHGFVSTIS------------------------EYPIDESLLTAASVVFDAVYVAGGNS--ETLAGNPDALHFVAEAYKHCKPIATAEDASDFLNKA-------IP--------------------------------------------------------------------------------------- +--TRQVAFLCA------------EGVNAESIKTMKLALKDAGAKAVIIAPHLGTIVSEE------------------------EIPVDQSYLIAASVLFDAVFVPAGKG--TALKDKKEVGEFIKDAYHHCKFIAAEGQGIQVLPLK-------D---------------------------------------------------------------------------------------- +--NRKVAIVVA------------DGFRGAETAELAAALTAAGALPEYLSSTLGMVSGDD------------------------EVEAAHSFLTSDSVLFDAVFVAGGEA--AMLKN-PKLPDFLKEAFQHFKAIGFGSPAAQLLELA-------GL--------------------------------------------------------------------------------------- +--TRKVALLAA------------DGVDVALVGDLVAQLRERGVTAEVVGLHGGALSGQSVS----------------------TIGVDKALPTTASVLYDAVLLGGGEQ--QAVGANTDARRFVAEAYRHGKPIGALGPGIGLLTDV-------TG--------------------------------------------------------------------------------------- +--TRQVAILAA------------DGADATSIAAITKALQAGGAVAKLVAPHLGQLRT-T------------------------ALRIDFSLQTTASVMFDGVYVAGGEQ--QALRHQPDAVHFINEAFRHCKPVGSADAGRELLQAA-------AY--------------------------------------------------------------------------------------- +--GRHVAILAA------------DGVDGAQLATLKHALSAMSISADIVSKMGGTIASAD------------------------SIEVDKTFLTTASVLYDAVYVPGGSQ--EALKAHGEALTFIHEAFKHFKPIAGSGEGVDLLMQA-------DL--------------------------------------------------------------------------------------- +--GRRIAILAA------------DGFDGSQLMEIKQALKSGGAQAEVVSKFKGMIKSAD------------------------EVEVNKTFLTAASVMYDAVYIPGGKE--ETLKKEGDVVEFINDTLKHYKAIAATGEAVDLLMMA-------PE--------------------------------------------------------------------------------------- +--AKKVAIFTA------------PGIDVSEAKSMFDFLENEGAYPEYVG-----FKG--QD----------------------GIVTNHTFLTTSSVLYDAVYVPSGEK----F-PYNEPSVFLLDAYRHGKPIAASGRAATLLKAA-------QL--------------------------------------------------------------------------------------- +--SRKVAFLCG------------EGFNEASVNALKEALEAKGAKAKIVGPHAGAITGDA------------------------ATKTDFTFFSSSSVLFDAIYIPDAKG--KALEANDNVIQYINDAYRHCKVIGADIGTDTLLSKT-------TI--------------------------------------------------------------------------------------- +--TRQVAFLAA------------NGVESTDFENMKKALLAAGAVVKVVAPKNGTLKDSA------------------------EIKIDMSFLTGTSVVFDAVYVPGGGK--DALLAEPDAVHFINEAYRHCKAIAATGKGAELINQS-------YV--------------------------------------------------------------------------------------- +--GRKVAIIAG------------EGHDAAEVAALQAALKAEQVSWHLIAPTLAPVKDSK------------------------SVTPDATLENTRSVLYDAVFVPGGKE--DGLRLLGKAKAFVAEAFMHCKPIAVGVNAAAVLDDA-------NL--------------------------------------------------------------------------------------- +--TRRIGVLVA------------DGFDTAELQSTKAAIEQAGGELVIISRRLGMVKGAD------------------------SVKVDKSALTTGSFEYDAVFVPGGAA--SVLKKDGDSVHFIQEAYRHCKPIGVTKEATGLLEEA-------DV--------------------------------------------------------------------------------------- +--TRKIAFLVA------------PGFNNAQLTTVAAGLTAAGAMAMYVGPRKGEVKGDA-------------------------TTCQFSYLTARSVMFDGVVVVGGGQ--AALSRSGECKAWINESFKHGKPIAALEEGVDFVQSL-------GL--------------------------------------------------------------------------------------- +--TRRVAVLVD------------SGVEIGALKIFQQALAEHQVTLKIVAGHLGVVSTSS------------------------QLQVDHCFLTASSVLFDAVLVPGGAA--QALAANGRAVHFVLEAYRHCKPICVIGEGVELLRSL-------GI--------------------------------------------------------------------------------------- +--TRKVAVLVA------------PGVEVGAYKVLQQALQDQGALTRVVSAQLGVVSTSS------------------------QLAVDHTFASTSSVLFDAVLVPGGSA--QALARHAPALQFVHEAWRHGKALCLIGEAVDLLQGV-------VP--------------------------------------------------------------------------------------- +--TRKVAALVA------------DGVSEGELKDVKTALESAGATVEVIGPRLGKLKSAE------------------------AVPVTMALPTTASVMFDAVFIPGGKA--EALLKDGSAIHFVLEAFKHHKTVGATGEGVDMLRAV-------PF--------------------------------------------------------------------------------------- +--TRRVAILIA------------DGFDYDAYTTMKDALTERGAFVFTIGAQRKGV----GQ----------------------TVTPDHFFVGMRSTLFDATFVPGGKH--EGLAKSGVAKHWIAEAFSHLKAIAGVNEAVPFIKKQ-------I---------------------------------------------------------------------------------------- +--TRRIAILLA------------DGFDYNAYVTMKDALSERGAFVFTIGAQRKGV----GQ----------------------TVVPDHFFTGMRSTLFDATFIPGGKH--EGLAKNGVAKFWVTESFAHLKPIAGLNEAVPFIQKQ-------I---------------------------------------------------------------------------------------- +--GRKVGVMVS------------DGCDDKLVANLKAAVEAAGARLQVIAPTIYGVTTAG------------------------VLPADHKIDGGPSVLFDAVAILPSED--EQLALEAAAVNFLRDAYGHLKVIAYLPSAAPLFAAG-------GI--------------------------------------------------------------------------------------- +--GRKIGLLTT------------AGVDAEFVKSLQQALKQEQASLAIIAPTAGPFKDSE------------------------EIVPDDFLDGAPSAIFDAVVVAPGPQ--DMLLSTANAVNWPRMAYGHLKAIAFTAEAADLLQKG-------NV--------------------------------------------------------------------------------------- +--SRKIAILIA------------DGFDLIGYEGIKAALLSGSAVVGTIGIRKSGVKA--GK----------------------VTKPDFHFEGDRSTSYDAIIIPGGE---KVLAANGRVIHWIREAFGHCKPIGAFGEAVDLVKAA-------L---------------------------------------------------------------------------------------- +--TRKVAILVA------------DGIDSASLKPIREALEQAGAQCKVVGPRLGSVVSGS------------------------QVDTDATFANMPSVMFDAVLVPAGAE--RALAASGDAVHFVLEAFKHCKAVCTVGEGVQLLSTL-------GI--------------------------------------------------------------------------------------- +--SRQVAFLAA------------DGVDVASLQAMKAALIKGGAAVKVLSTRLGTLKGAA------------------------SLPVDHLIVTMPSVVFDAVCVFGGAG--AQLKASGDAVHFVREAFKHAKPVAGLAEGRDFLTAA-------GV--------------------------------------------------------------------------------------- +--TRKIAVLVA------------DGVDAPAMRRLVLDMTASGAICKVVGWQLGNVATLT------------------------QLTVDHTFSTMPSVMFDAVLIPGGEK--ATLCRLGDAVHFVLEAYKHGKTICALNEGHQLLVTL-------GF--------------------------------------------------------------------------------------- +--TRRVAVVAA------------DGVDVVSLRIVQHALTDAGAVCTVVAPRLGAVATAG------------------------RLDVGGTFAGSPSVMFDAVLVAGGKD--DTLSQLGEAVHFVLEAYKHCKPICVMGEGIAMLRLL-------GV--------------------------------------------------------------------------------------- +--TRRIAIIAA------------NGYNHNDVSQVMQALEAGGARAHIISKHQGMLKSSS------------------------SIEVDKSYVTTASVFYDAVYIPGGKE--ETLKMQGDAIHFVNEAFRHCKPLGATGEGIELLKAA-------NL--------------------------------------------------------------------------------------- +--SKKVAILAC------------KDVAADQLKSVKGFLEGQGAVVDVVSFKLGKI---E------------------------DIEATQTFATADSVFYDATFVPGGKSR-QNFWDFEDTWAFVRDTYRHAKPLAALGESVSFVENA-------IK--------------------------------------------------------------------------------------- +--GRKLGLVLT------------EGADAGMVSGILDAVMDAGGVPVLICPRVGGVTDSD------------------------LRPADEALEGAPSVLFDAVAILASKE--EELAGNPAMRDFLADAHSHKKFIAFSPDASVLWQAA-------GL--------------------------------------------------------------------------------------- +--GRKLGILLA------------DGADADLVAQLRAAASAQQITVEVIAATIGGATASD------------------------TITADQRVDGAPSVLYDAITLITGTA--HQLVGSPAARDFLADAYAHCKYIGYTPDAEPILRAA-------GL--------------------------------------------------------------------------------------- +--GRKLGLLIT------------DGADADLVKALMAALEAADAMCEIVAPRIGGATLSD------------------------LIPAQQKIDGGPSVLYDAVAIIASAQ--AMLAMDAPAKDFVTDAFAHCKFIGLSTETEPLLVKA-------GI--------------------------------------------------------------------------------------- +--GRKLGILLS------------DGADAALFGGLVKALDKVGAVYDVIAPKIGGVTLDD------------------------KVAAKQKIDGGPSVLFDAVAIVVSAD--ALLADDAATQDFVRDAFGHCKYIGLTLDAQPIFANA-------GI--------------------------------------------------------------------------------------- +--SRRIAILVA------------DGYDQVAYSAAYAAISAGLAIPLVIGTKRSKIVAGG------------------------STTPHHHLEGFRSTMVDAIFIPGGVD--RALSKNGRALHWIREAFGHLKAIGATGEAVDLVNKA-------I---------------------------------------------------------------------------------------- +--SRRIAIIIA------------DGYDPIAFNAMYGAIKAQSALPFVIGPRRSAIFANESK----------------------GIVPDHHLEGQRSTMFDAIFVPGGQK--QTLSKNGRALHYIREAFGHLKAIGGTGEAVDLINKA-------I---------------------------------------------------------------------------------------- +--SRKIAVLAA------------DGVNSSSVTHLKSALEGAGAVVEIIAPRLGFISGTD------------------------KINVDQSFLTAASVLFDAVYVPGGTD--AAVAAEANAIHFLNEAFKHCKAIAADESALPVLKVT-------YF--------------------------------------------------------------------------------------- +--GRKIALIAG------------NGVDGVALNAIKERLSAEKALVKIVSSNLGTINTNE------------------------IIKVDFNFLTTSSVLFDAAFVFDNSN---SFLHQTEVLEFIKEAYTHCKPIAIPFGLIDRPELT-------N---------------------------------------------------------------------------------------- +--TRRVAFLAA------------DGVDDDALDAMKKSLTEEGAMVKIIASRHGSIKTAS------------------------EVEVDATWLTTSSVLFDAVYIPGGKT--DALAEEMDAIHFVNEAFKHCKAIAGVGEGVEFIKSQ-------TY--------------------------------------------------------------------------------------- +--TRQVAILAA------------DGVDNTEFDVIKQALSAEEAVIAIVAPRLGKLKTST------------------------AVKIDASLQTTASVLFDAVYVPGGQT--NSLLQEADAVRFVHEAFMHCKPIAATAEGVDLLKAA-------AN--------------------------------------------------------------------------------------- +--GRKVAVLVA------------NDVDGTTIESLRVALRAAGATLKVIAPHLGEIRSGA------------------------TLTVDHSLSTVGSVQFDAVYVPGGAK--DALCKNAQALLFVKEAYKHGKPIAATDDGAMLIDKA-------AR--------------------------------------------------------------------------------------- +--TRQIAILAT------------DGVDKVSLLTMKQVLEDAGAQTKIIAPHLGFITPNN------------------------PIKVDQSFLTAASVLFDAVYVPDGQQ--AALAQEQDAIHFINEAYKHCKAIAADGAGVKLIDAT-------AA--------------------------------------------------------------------------------------- +--SRLVALLVA------------DGFVVAELAAVKAALEAAGAHAQVVSTRLGPILGDD------------------------AVEADRSLLTAKSVMFDAVYVPGGRA--AALAASGEAVHFVNEAFKHCKAIGATGDAVDLLVAT-------DI--------------------------------------------------------------------------------------- +--TRQIAILAA------------DGVDEASISQMKSALEAEGAQTAIIAPKLGYIKSAT------------------------EIKVDQSFLTASSVLFDAVYVPGGAK--ASLKENAKALQFIYEAYRHYKAIAMDDDSGL-LKAS-------YP--------------------------------------------------------------------------------------- +--GRRVALLVG------------DGFDAAAVDLVKKGLAAEQGVPLLIGTKRSAITAGASP----------------------SVTPDHHLEGFRSTMVDAVFVPGGKA--EALVVKGRVLHWLREAFGHLKTIGATGEGIALVQEA-------LH--------------------------------------------------------------------------------------- +--GRRIGVLVD------------AGSDAQILAALRQEADAEGATLALVGPTREGIRDSA------------------------LLEIAEKLEGGPSVLFDAVAIVLSPA--GRMAAKFAARSFVADAHHHLKFIAHDAGGSGLLDAA-------GI--------------------------------------------------------------------------------------- +--GRTIGVLAS------------DGADADLLRGLMDAARAEGAKVKFVAPRIGGFTDSK------------------------KHPADEKVDGGPSVLFDAVAIVPGEE--AALAAMPPARDFLTDAFVHAKFIALAPAAGPLVEAT-------GL--------------------------------------------------------------------------------------- +--GRTVGVLAG------------NGVEAELLTELRSILQAEGAMMKLVAPRVGGVTDSA------------------------LHPADEKLGGGPSVIFDAVAVLPGSD--AMLAANPAAKDFLTDAHAHCKFIAHH-GAGPLIEAC-------AL--------------------------------------------------------------------------------------- +--GRRLGVLVS------------NGADAKTLRMLRKAAEAEGMMVELVAATREGVSDSD------------------------SLQIAEKIDGGPSVLFDAVAVVTTEE--SKLAAMPPARDFVSDAHAHGKFVAHVGAAAAIFDSA-------GV--------------------------------------------------------------------------------------- +--SRNVAILVA------------DGFDFAEYEAVKAALTAAGAFVATIGPRRGVVKS--GK----------------------EAQTDHHWEGIRSVAFDALYIPGGAH--TALGKSGRVMHWVREAFGHLKTIGATGSAVAFVQKA-------V---------------------------------------------------------------------------------------- +--SRRIAILIA------------DGVDATQVEALRAAFKSAMATTWLIGPRRGKVYAGQST----------------------GLWADHHFEGQRSTMFDAVIIPDGQA--NLLSKNGRAIHWVREAFGHCKAIGAIGDAVRFLENV-------V---------------------------------------------------------------------------------------- +--SRKIGILLD------------NGFNYQEFMQVKQALTEKGAHAKVISMYKGMLKSAD------------------------EVEVDKSHITTGSIMYDAIYIPGGQK--EAMKKQGDALHIINEAFKHCKPIAATSEGVDLLMAS-------DI--------------------------------------------------------------------------------------- +--SLKVAILAA------------NGVNVAQVKALKEALKAQGVESEVVAKFLGMLKGAD------------------------ELKVDKSHITTASIMYDAVLVPGGKK--EAMKKQGAAVHFLNEAFKHGKTVAALGEGVDLLAAS-------DI--------------------------------------------------------------------------------------- +--TRQVAILLE------------DGFDCNELVQVRQALMDAGAQVKIVSKFLGMRKASN------------------------EVKVDKSHITTASIMYDALYIPDGKA--EILMKEGDALHFINEAFKHCKTIATSGDGIRLLEKS-------GI--------------------------------------------------------------------------------------- +--SRRIAILIG------------DGFDSVAFNGVYTAVKAAGALPFVIGTKRQPVFDGVGK----------------------GVTPDHQYDGMRSTMFDATFVPGGPH--SLA-KIGQIRYWIAETFGHLKALGATGEAVDLVKQA-------LV--------------------------------------------------------------------------------------- +--TRRVAILIA------------DGFNYIEVQTMRGLLAMAKATCWIIGPRRGEVKESQGM----------------------TINADHHYEGQRSTLFDAIFVPSGPK--EALMQNGRAIHWIREAFGHCKAISAIGEGVAFLKHA-------I---------------------------------------------------------------------------------------- +--SRRIAILVG------------DGYDQVALISAKGAIKAAGAIPFIIGTKRQAIFDHEDK----------------------GLIPDHHYDGQRSTLFDATFIPGGSH--KLG-GIGQIQHWITESFGHLKPIGATGEAVNLVAQA-------LS--------------------------------------------------------------------------------------- +--SRRIAILIG------------DGYDAVAFVSAKTAIKAAGALPFIIGTKRQAIFDHEEK----------------------GVIPDHHYDGQRSTMFDATFVPGGSH--NIG-KIGQIRHWIAESFGHLKPIGATGEAVNLVAQA-------LS--------------------------------------------------------------------------------------- +--SCRVAILIG------------DGYDPVAFISAKTAIKAAGALPFVVGTKRQPIFAHQDK----------------------GVVPDHQYDGARSTLFDATFVPGGEH--RILSKIGQIRYWIAESFGHLKAIGATGDAVNLVAQV-------LG--------------------------------------------------------------------------------------- +--GRVVAVLLN------------ERTSAQDLVHLLQALQAQGVHSKLLYSRMGEVIADDGS----------------------PLPIAGTFAGSPSLTVDAVVVPGGDL----LSQSGDARYYLLEAYKHLKPILLAGD-RQLTSVL-------QV--------------------------------------------------------------------------------------- +--GRVVAILLN------------ERVKGADLLAILQSLKSQGVHSKLLYSRMGEIVADDGS----------------------QITVMGTFEGVPSLTVDAVIVPGGAV----LLSRGDARYYLLEAYKHLKPITLLGD-RQFKAVL-------GV--------------------------------------------------------------------------------------- +--GRVVAILLS------------EKANAADVLAAMKALKSEGVHTKLLFARMGEVAADDGS----------------------LLPIGATFAGSPSVTVDAVIVPGGDL----ILDNGDAAYYLLEAYKHLKVIGLAGD-RQFKSKL-------AI--------------------------------------------------------------------------------------- +--GRVVAILLN------------DKVVASELLSILQGLRAKGVHAKLLYSRMGHVTADDGS----------------------SLSVAGTFAGSPSVTVDAVIVPGGDV----LLNNGDAAYYLLEAYKHLKVIALAGD-RQFKQTL-------KV--------------------------------------------------------------------------------------- +--GRVVGVLLN------------DKVKAADLLTLLKGLKAEGIHAKLLYSRMGEIQADDGS----------------------AINIMATFAGAPSLTVDAVIVPGGDL----LKASGDANYYLLEAYKHLKPIVLAGD-RQFKTIL-------NV--------------------------------------------------------------------------------------- +--GRVVAVLLN------------DRVASADVLTLLAGLKAEGVHAKLLYARMGEVTADDGS----------------------ILPVAATFAGAPSLTVDAVIVPGGDI----IRNNGDAQYYLLEAYKHLKPIVLAGD-RQFKAIL-------NV--------------------------------------------------------------------------------------- +--GRVVAVLLN------------QNTASADVLTLLKGLKAQGVHAKLLYSRMGEVTADDGS----------------------KLPVAGTFAGSPSLTVDAVVVPGGDL----LLKSGDAQYYLLEAYKHLKPILLAGD-RQFKGLL-------NV--------------------------------------------------------------------------------------- +--SRQVALLVA------------DGVCGDSVATITTELNALGIHSKIFAPRLGKIKTLQGK----------------------EINADGTIEGNPSVLVDGVIVPAGKA--EVLKKNGNAKNYILQAFKHLKAIGLQGEALSLYEAL-------PL--------------------------------------------------------------------------------------- +--GRKVAILAT------------DGVCGESVDNIREILSKNKIYSLLLAPHMGMIKTLQ------------------------MLKVDGTIEGNPSVTVDAVIVPTNQ---MMLVKDGNAKYYLQQAYKHLKAIALHDNAKALFDHS-------GL--------------------------------------------------------------------------------------- +--SRQVAILAA------------DGVCGESIDNIMKTLKKHGIHGKVFAPHLGRITSLQGN----------------------EIEVDGTIEGNPSVMVDAVIIPEGEG--DSLMKNGNAKHYVIQAFKHLKAIGLQGKAFKLYDAL-------PL--------------------------------------------------------------------------------------- +--GRVVAVLLN------------DAPRASDVLAVLQALKAKGVHAKLLYSRIGDVIADDGS----------------------VLPVAATFEGSPSLTVDAVVVPCGDI----LLKSGDAVYYLLEAYKHLKPIALAGD-RQFKPLL-------KV--------------------------------------------------------------------------------------- +--TRKIAVLVD------------DGYDSDHLETVVSTLEDEGARVKVVSKMLGDAEAEN------------------------TVEADKSHATAESVLFDALFVPGGED--DALLEQGDAKHFVAETFKHKKPIAAAGAGTDLLEAV-------DL--------------------------------------------------------------------------------------- +--GRQVALLLS------------DGVKSADVLAVLQALKAAGVHTKLLAAHMGQILADDGS----------------------VLPVDATFTGLPSLTFDAVYVPDGNI----LLLSGDSRYFLLEAYKHLKVIGLSGE-RRFKAQF-------AL--------------------------------------------------------------------------------------- +--GRQVALLVS------------EGVNADDVLHILQHLKTAGVHTKLLAAHMGQVSADDGS----------------------QLPIDATFNGLPSLTFDAVIVPDGNM----LLKSGDARYFLLEAYKHLKVIGLSGE-RRFKAQF-------DL--------------------------------------------------------------------------------------- +--SRRVAIIIA------------DGYDATAFNAAKAAVTAASALPFVIGTRRSEIYAGAGN----------------------GVVPAHHLEGQRSTMFDALFIPGGEE--KTLRKSGRAMHWIREAFGHLKAIAATGEAVELVNAA-------I---------------------------------------------------------------------------------------- +--SRRVAIIIA------------DGYDATAFNAAKAAVTAASALPFVIGTRRSEIYAGAGN----------------------GVVPAHHLEGQRSTMFDAVFIPGGEE--RTLRKSGRAMHWIREAFGHLKAIAATGEAVELVNAA-------I---------------------------------------------------------------------------------------- +--GRQVALLIS------------DGVDAADVLAAMQALKAEGVHAKLLAS--------DGS----------------------TLPIDSTIEGNPSITVDGVVVPNGN---DALLRDGAARHYILETYKHLKPIALSGDARRFKPQL-------GL--------------------------------------------------------------------------------------- +--GRQVALLMS------------DGVIAADTLAILMELKQHGVHAKLIAPHMGQVRADDGS----------------------DLPIDATFSGLPSLTFDAVIVPDGNI----LLLSGDARYFLLEAYKHLKVIGLSGD-RRFKSQF-------GL--------------------------------------------------------------------------------------- +--GRQVALLVS------------DGVKAADVLAMFQELKARGVHAKLLAAHMGKVRADDGS----------------------VLPVDATFNGLPSLTFDAVLVPDGNI----LLLSGDARYFLLETYKHLKVIGLSGD-RRFKAQF-------SL--------------------------------------------------------------------------------------- +--SRRVALLVA------------DGVSKESIETISNMLHKEGVYPQFFAPHMGSIKTEE------------------------EITVDGTIEGNPSVVVDAVIVPQGKQ--NTLLNDGNAKYYLCQAYKHLKPIGLPGNTKEMLSYI-------GL--------------------------------------------------------------------------------------- +--GMRVSLLAA------------DGVSLKSVEEICSALHKEGVHPQILAPHMGSVNTEEGK----------------------DLLVDGTLSGNPSVVFDAVIVPEGEQ--KTLLMNGDAKYHLRQAYRHLKAIGLPGDASEMLEAT-------DL--------------------------------------------------------------------------------------- +--GRVVGILLN------------GKVKSADLLTILQALKAKGVHAKLLYSRMGEVVADDGS----------------------TLTIAATFAGAPSLTVDAVIVPCGDI----IENSGDARYYLLEAYKHLKPIALAGD-RRFKAVL-------NV--------------------------------------------------------------------------------------- +--SRRVAIIIA------------DGYDPIAYHGIKAALKAAQALPFTIAPRRTPIFAGEGK----------------------GVVPDHHLEGMRSTMFDSVFIPGGEQ--ATLKKNGRAIHWVREAFGHLKAIGGTGEAVSFIKDA-------C---------------------------------------------------------------------------------------- +--SCRVATIIA------------DGFDLVGYAGIKAALTAAQAFPFTIGSHRSPIFAGKGE----------------------GVKSDHHLEGMRSTMFDSIFIPGGAE-----------------AFGHLKAIGAVGEAAALVKNT-------V---------------------------------------------------------------------------------------- +--TRMVAILIA------------DGYDSVAYNAIKAALAAQGALPFTIAPRRTPIYAGEGK----------------------GLVPDHNLEGQRSTMYDAIFVPGGAD--ATLRKNGRALHYVREAFGHLKSIGATGEAVAFVKDA-------C---------------------------------------------------------------------------------------- +--SRRVAIIIA------------DGFDPAAYAGIKAALTAAKAFPFTIGTRRSPIFAGEGK----------------------GVKPDHHLEGMRSTMFDSVFIPGGAD--ATLRKSGRALHWVREAFGHLKAIGAVGEAVDFVKDA-------V---------------------------------------------------------------------------------------- +--TRMVAILIA------------DGYDAVAYNAIKAALAAQGALPFTIAPRRTPIYAGEGK----------------------GVAPDHNLEGQRSTMYDAIFIPGGAD--ATLRKNGRALHYVREAFGHLKAIGATGEAVKFVQDA-------C---------------------------------------------------------------------------------------- +--TRRIAILVA------------DGFDLATFTAIRAAFKAQGAITFVIAPRRHMIYEGS-E----------------------GVMPDHHFEGQRSTMFDATFVCPGAN--LTLRECGRAIHWIRESFGHLKAIGALGDGCAFLQEA-------V---------------------------------------------------------------------------------------- +--TRRIAIVIA------------DGYDKVAYNGIVAAAKACQALPFTIAPRRSPIYAGESQ----------------------GVKPDHHLEGMRSTMFDSVFVPGGAD--ATLRKTGRALHWVREAFAHLKAIGAVGEGVDLVRDA-------C---------------------------------------------------------------------------------------- +--GRVVGIVTD------------GSTDADGVRALRQAVLDAGMVPLVVAPAGGKLGD-G------------------------AITVQRTFATTRSVEFDALVLVGTPAG-RGGVVDPRLALLVSEAFRHAKAIGGWAGAETVLEAA-------SV--------------------------------------------------------------------------------------- +--GRIIGIVTG------------PDGDLDGVRAVRQQVLDGGMVPLIVAPAGGTLGD-G------------------------ALTVQRTYATARSVEFDALLVAGTPGNGHQATPDPRVGLLLAEAFRHGKAIGAAKGGQSALEAA-------GI--------------------------------------------------------------------------------------- +--GRVVGIVAD------------DSADLDE-RFLRSAVFNGDMVPLIIAPTGGELGD--DD----------------------PLTVQRSFVTGRSVELDALILVSAPTGADAS-VDPRVELMLTEAYRHAKPLGALTAARSAFDSA-------RI--------------------------------------------------------------------------------------- +--TRKIAVLLD------------DGFEDDHVSRTVSALEEENARVKIVAPAFGEREGAD------------------------TVEADESLSTAESVLFDAVLVPGGGD--DALEKQGDVRHFVEEAFKHKKPIGALGEGTELLESV-------DL--------------------------------------------------------------------------------------- +--TRKIAILLD------------DGFEDEHVKRLQSALDDAGARTKIISKVVGEKSGTD------------------------SVDADQNHVTATSVVFDAIVVPGGSD--DALAQQGEPKQFIEEAFKHHKPIAALGDGTELFEAV-------DL--------------------------------------------------------------------------------------- +--TRKVAFLIA------------DGVSKKSIDKMKTALEEEGAEAILISTNVGKVQFKE------------------------TADIEFSYLTEASVCYDAFYT-PEGD--SVLQDEPDYLHFINEGFRHCKAIAFATDAEKLIDGT-------YL--------------------------------------------------------------------------------------- +--GRVVAVLLN------------DHVKSADLLAMLQALKSHGVHAKLLYSRMGSVTADDGS----------------------QLEVAGTFAGSPSVTVDAVLVPGGAA----LADNGDAVYYLLEAYKHLKAIGLMGD-RGLKSRL-------AV--------------------------------------------------------------------------------------- +--SRRVAIIIA------------DGFDKTAFDAIAKTLKASSALPFTIAPRRSEIFGGVGN----------------------GVQPDHHLEGLRSTMFDAIFVPGGAG--ETLQKSGRAIHWLREAFGHLKAIGATGEAVQLLVQA-------F---------------------------------------------------------------------------------------- +--SRRVAILVA------------DGYDSIALNGVKAALTASSALPFIIGPRRAEIFAGSGS----------------------GIKADHHFEGMRSTMFDAVFVPGGAD--KALSTNGRSLHWLREAFGHLKAVAGSGEAVELFKIA-------F---------------------------------------------------------------------------------------- +--SRKVAILIA------------DGYDSIAYNAIFVALKAARAIPVVLGPRRSAIYAGQGK----------------------GLVPDHHFEGQRSTLFDGLFIPGGEE--ATLKKMGRVTHYIREAFGHLKTIAATGEAVDLVRHA-------V---------------------------------------------------------------------------------------- +--GRLIAMIAP------------DGFDYQQAVAVQKAFSSLGNIVAVIGTRKGPTYK-N------------------------QLDTQFTFELARSTYFDSLIFLDG-N----L-QMGRPKHWCIEAYAHYKPLAVVGSSAEWASKL-------I---------------------------------------------------------------------------------------- +--GRRIGILAL------------DGFDSLQVTGMVAAITALGSIPNVIGSRKGPAFR-GSG----------------------VISTNFTLESARSTLFDAIFIPDG-D----L-STGRALHWIREAAGHFKTIGAVGASVSVLAHK-------AL--------------------------------------------------------------------------------------- +--GRKIAMFCL------------DGYDGLQAKAMMTALMGAGVIVQVIGSRKGPAYK-GAG----------------------VISTNFTPESCRSLMFDAVFFPSG-D----L-KSGRVTHFAREAFGHFKAVAAAGTACTWLMKT-------AL--------------------------------------------------------------------------------------- +--GRRIAVFAL------------DGFDSLQVSGMVAAITALGSIPNVVGSRKGPCYR-GSG----------------------VINSNFTLETARSTLFDGLFIPDG-D----L-SSGRGLHWIREAFAHFKTIGAVGASVPVFAHK-------AL--------------------------------------------------------------------------------------- +--TRRVALLVA------------EGVSAKALRPLAEALAAQGAVPVHVGPLLGAVRADR-G----------------------ELPVDATYENSPSVLFDAVVLPADEASLAALDAHADVGDFVREQYRHGKAIGVAGGALQVLERW-------GI--------------------------------------------------------------------------------------- +--TRKVAILVA------------EGADGKAVAAVAQGLIAAGAVVRLVGQRIGPVPTDEGG----------------------AVDADASLDNHPSALFDGAVVAGGEAAVARLREDGRALEFLRDAFRHGKTLMGVGAGAQLFAAA-------GI--------------------------------------------------------------------------------------- +--GRKVALLVA------------AGCDEAMVDALQAELEAQGAVTRLVAPHVGLVG---------------------------GLEADMSLETGPAVLFDAVVVPDGSAAAEALAANALAVEFVTLQYRHCKPLMVVGAGATLLAAA-------GI--------------------------------------------------------------------------------------- +--TRRIAVLVA------------DGSRAMDVTTLHEGLTAQGAVVRLLGPHVGRLQDADGA----------------------AFDADASLENEPGVLFDALAVVGGAAAAAVLAADVRALEHLRDGYRHGKPLLFVGEGRQVWDAT-------GV--------------------------------------------------------------------------------------- +--TRKVAILAA------------EGVDGKALSAVADALMQAGAVVRLVGQRIGPMQTSEGG----------------------AFDADASLDNHPSVVFDGAVVVGGADAVQRLAADGRALEFLRDAYRHGKTLMGVGDGVQVYAAA-------GI--------------------------------------------------------------------------------------- +--TRKIAILVA------------EGVDGAAVSAVAQALIQAGAVVRLVGQRIGPVATAEGD----------------------ALDADASLDNQPSAVFDGAVVPGGGMAVDRWRQDGRALEFVRDTYRHGKTLLAMGEGADLLEAA-------GI--------------------------------------------------------------------------------------- +--SRKIAILIA------------DGVNGETVSVLQKALLDAGAVPRLVGQRLGVVNSQGTA----------------------VLDADASLENSPAVLFDGAVVADGSL-AQTLASDGRAAEFLKDQFRHCKTLLAVGEGASLLEGA-------GI--------------------------------------------------------------------------------------- +--TRKVAILVA------------EGVDAKAVSAIADALIGAGVVVRLVGQRIGPIAAEGGR----------------------MLDADASLDNQPSALFDGAVAPGGGPAAERLRADGRVLEFLRDAYRHGKTLMGMGEGKQLFAAA-------GI--------------------------------------------------------------------------------------- +--SRRIAIIIG------------DGYDPIAFAGIRRAAAAAGALPIVIGTRRQPIYQGEGK----------------------GVIPDHQYDGVRSTLFDATFIPGGPH--TLATQNGQIRHWIAETFGHLKTLGATGEAVALVKQV-------LS--------------------------------------------------------------------------------------- +--MRRIAILVA------------DGIDGR-ITTLHAGLLGEQAVPRFVGARLGSVQTTE-G----------------------KIQVDVTLEAMPSVLFDALVVPGGSEGVEALARLGQALEFVKEQYRHCKPILVLGYGRKLIEAS-------GI--------------------------------------------------------------------------------------- +--TRKVAILVA------------EGVDGQAVSAVAQTLIKAGVVVRLVGQRIGPLQAEDGS----------------------ALDADASLDNHPSGLFDGAVVPGGDAAAKRLQADGRALEFLRDAFRHGKTLLGLGQGAQVFGAA-------GI--------------------------------------------------------------------------------------- +--GRRVALVVA------------HGVQGAAAERLQAVLSAEGAVAEFVAPRVGRVRGADGV----------------------DLEATASLENNPGFLYDALAWPDGEEGVATLAQDGHTMESLKDGYRHGKALLLVGAAQTLLDMA-------GV--------------------------------------------------------------------------------------- +--TRQVAILLA------------AGVDATSLHAVSSALQAEGAVVRLVGPRVGPFNAADGS----------------------VIEADCSLENQPAPLFDALVVPDGQDASTALQADGRALEFVRDSFRHGKSILAIGAGTQLLEKA-------DV--------------------------------------------------------------------------------------- +--GRKIAILVA------------AGVDGEGALAVHRALTEAGAVPRLVAARLGPVESSTGD----------------------ALDPDATLETMPSCLFDAVVVPDGEACAAALSALGHAVEFVKDQYRHCKTLLAIGAGQRLLAKA-------GL--------------------------------------------------------------------------------------- +--TRQIALLVA------------DQVNADAVLATAQALIDRGAMVRMVGQHVGIFAADDGT----------------------QLDADASLENHPACLFDGVIIPDGQAAITLLSDDGRALEFLRDQYRHAKTILAIGAGRQLLEAA-------GI--------------------------------------------------------------------------------------- +--TRRIALLAA------------HGVAGKPIAKLMAALLKAGAVATVVAPRIGAVTTADGE----------------------PLVATGSMENSPPVLFDAVVLPDGAKGVDVLLGLGQALEYATLTWRHGKTLLALGAGRALIEKA-------GV--------------------------------------------------------------------------------------- +--TRCVALLAA------------DGVDGTSIALLQAALQEAGAVAKVVAPRIGAVKTAGGP----------------------AVEATASFENAAPVLFDAVVLPDGEAGVALLASDAQAMDFVHLQYRHGKSILALGASKALLDQA-------GI--------------------------------------------------------------------------------------- +--TRKVAIFVG------------DGVNADTVAALQSALLAQGATGRLVGHRVGQFTAADGS----------------------AIDADASFENEPSVLFDAVAVPDGQQAAKTWGLDGRACEFIKDQFRHCKTILAVGDAAAFVEST-------GV--------------------------------------------------------------------------------------- +--ARKIAVLVT------------DGTDVEVVRTVSEALGARRADVRLVGEHIGLCPAC-GG----------------------MLDADAALDSQPGFLFDAVVIAPGDPAVDRLCSNGHALEFVRNQFRHCKTLLAIGEGRQLLDAA-------GI--------------------------------------------------------------------------------------- +--TRKVALLVA------------DGVQGEQIAAIQAALLAEGAVGRLVGPRIGPFRTAEGE----------------------TMEADASMENEPGFLFDALVLPDGAEGVELLSAHAYTEQFIKDQYQHGKTILALGASATLLAEA-------KI--------------------------------------------------------------------------------------- +--TRKVAIVVA------------NGVVGEGVAAIQAALRDAGAEGRLVGPRIGPFTTAEGD----------------------VMEAAASLENEPSVLFDALVLADGAEAVATLAGMGQMAEFIRDQYRHCKTILALGAASGLLTQA-------GI--------------------------------------------------------------------------------------- +--TRRVALLVA------------ADVDLQALVDLHAQLVAAGALPRYVGPKLGRIEGASGS----------------------SVDVEVSFETAPSVLWDAVVVPGHDD---VLATLGHAKDFLKDQFRHCKPIFLMGDPSALADAI-------EL--------------------------------------------------------------------------------------- +--TRRIAILVA------------DGVNGDDARRAHEILTAQEAVPRFVGIKMGTARSDAGD----------------------PIEVEVSLEAAPAVLWDAMIVPGGEGATEAFSESGQALEFLKDQYRHCKPILMLGSAGELLDQA-------RI--------------------------------------------------------------------------------------- +--TRKIAILVA------------DGAEGGSIGKLVTALVQAGAVPRLVGPRLGTYTAADGD----------------------KLEADASMENSPGFLFDALVLPDGLAAVEALAADGHSMEFVKDQYRHCKTILALGAAQALLTEA-------GI--------------------------------------------------------------------------------------- +--TRKVAILIA------------HGVEGTSLAKLISALVEAGAVPRLVAARLGTYSGAAGE----------------------SFEADATMENSPGFLFDALVLPDSAAAVEALDADAHTLEFLRAQYWHCKTILAFGASEALLAEA-------QI--------------------------------------------------------------------------------------- +--TRQVAILIE------------DGVRYSSLLCLYDALTEAGAVVHFVGPRIGIFTCASGE----------------------KIEADRSLENSPAVLFDAAVLPDGNEAIRALAANKHSLGFIRDLYQHCKTILALGDGRELLDIA-------GV--------------------------------------------------------------------------------------- +--TRQIAVLIE------------DGVHHASLVSLHSALVEAGAVVHFVGPRIGGFVGASGE----------------------KIEADKSMENSPAVLFDALVLPDGNEAVQALAGYSHTIPFIKELYLHGKTILALGDGRELLDLA-------NI--------------------------------------------------------------------------------------- +--GRKVAIIAS------------HGVDAAGVQAVYADLLKAGAVPRVVGPYLGQLKAADGS----------------------ALDVEISFEAGPAVLYDAVVIADGEGSAKSLQAEAIALDFVRQQYNHCKPILAIGAGADVLKKL-------GV--------------------------------------------------------------------------------------- +--TRRVAILVA------------PGVDGAQVNSLYAGLLKEGAVPRLVGSMLGKVKPASGA----------------------ALDVEISLEAGPSVMYDGMIVPDGAA-AEALARNAHAIDFVREQYRHCKPILVMGAGAELLARA-------MV--------------------------------------------------------------------------------------- +--ARQVAILLA------------PGVDEASAKAIQSALLADGAVPHLLAGTLNPVACAGGA----------------------TLPVEKTFENAPPVLFDAVAVPDGAAAAEQLMKDALALDFVRQQYRHCKPLLVVGAGTALLGKA-------GI--------------------------------------------------------------------------------------- +--TRRVAILAG------------HGVEAASVKAIYADLLAAGAVPRIVAPQLGQLTTADGG----------------------KLDIEISIEAGPAVLYDAMIVADGAASAAMLMGDADALDFVRLQYRHCKPVLAVGAGAELLAKA-------GV--------------------------------------------------------------------------------------- +--SRKFAILVA------------DGVNGQTVETVQRALLDAGAVPRLMGVRIGPCVTDRGD----------------------TLDADVSLENEPGVLFDGMIVPDGADRMGELRMDARTLDYLKEQYRHCKALLILGDSDALLDAA-------RI--------------------------------------------------------------------------------------- +--TRKIAILIG------------EGSDADQVAALQKALLAEGAVGRLVGPRVGAFTAADGA----------------------SLDADASLENEPSVLFDGVAIPGGEGAV-RLTRDGRAVEFVSDQFRHCKAILALGDGADLLQEA-------GI--------------------------------------------------------------------------------------- +--TRKVAALVA------------DGCDAAALQAVRAAVVAAGAVLRCVGPHVGALRAQGGE----------------------AVDADASLENEPAVLFDAVVLPDGEAAVQALAENGLAAEFVRDQYRHGKPLLALGAAQSLLGLF-------GV--------------------------------------------------------------------------------------- +--TRKVAIFVA------------DGVDAEAVRGLQAALFAAGAVARLVGPRIGPFADGGGE----------------------GVDADASFENEPGPLFDAVAVPAGV--LEALKTDGRAAEFLQNQFRHNKPMLAVGDGNALLEGA-------GI--------------------------------------------------------------------------------------- +--TRRIAILTT------------DGVDVAALSRICDVLLQQGAVPRVLAPTLGAVKGAGAG----------------------GWQADITIEAAPSALYDALIIAPGEASTTSLCENGLAVEFVKDQYRHCKPILVIDTGADLLDRA-------GL--------------------------------------------------------------------------------------- +--TRKVAILAA------------NGVDAISVNAIYDAILSQGGVPRLLSIKLGKVETAQGS----------------------ALDAEATLETMPNVLFDAMVIADGERSIANLALDGRTVEFLRDQYRHCKPILVPRGASHLLRKA-------GI--------------------------------------------------------------------------------------- +--TKRVAILAA------------HGVNGANVNALYDAILAQGGVPRILSTKLGKLETSEGK----------------------TIHVEATLETMPGVLFDGMVIAEGEQSVANLALNAHTCEFLQNQYRHCKPILVPNTARSLLQKA-------GI--------------------------------------------------------------------------------------- +--GRRVAILVA------------DGVDGDSVQTLYDAILAEGGVPRLLGLQLGPVKADSGA----------------------ALDAEGSIETMPSVLFDAVALPDGKLVAENLAASGQTLEFLRDQYRHCKPMLAIGASQQLLQTA-------GI--------------------------------------------------------------------------------------- +--TRRVAILVA------------DGVDDAGITTIYEHLLKEGAVPRLVGQKLGPVNTSQ------------------------QLQAEITVSAGPSVLYDAVVLPDGEQASTLLAADPQVAEFVRDQYRHCKPLLALGSATAIIDEA-------GL--------------------------------------------------------------------------------------- +--TLRVALLVA------------PGVDAGQVRELYAALLDGGAVPRLIGERVGPLPG---T----------------------DLDVEISFETGPAMLWDGAIVPDRADGGTLLNREVVAVEFLRLQYRHDKPLLALGNGAQLVYAA-------GL--------------------------------------------------------------------------------------- +--GRRVAVLVA------------SGVDDKAVKKQYASLLKDGAVPRMVGNMLGKVTAVDGD----------------------PIDVEISVEAGPSVMYDGVIVPDGAAAAEALAKNAQVLEFLREQYRHGKPILAYGSGSDLLTKA-------MI--------------------------------------------------------------------------------------- +--TLRVAILVG------------PGSDGAQVRNTYAALLADGAAPRLVGSHLGTVDTSSGA----------------------PLAVEISLEAGPGVLFDAVVVPDGQGAVQQLGSDANALDFLRLQYRHCKPMLVIGAGKDLLDKA-------GV--------------------------------------------------------------------------------------- +--TRRVALLVA------------PGVDGPQTRKLYAALLDLGAAPRLVGEQIGKIAASEDA----------------------PLDVEISFEAGPSVLFDAVIVPDYPEGECALSRDARVLEFLKLQFRHLKPMLAIGGGAVLLRTA-------HI--------------------------------------------------------------------------------------- +--AHKVAILAA------------PGSDVAQLRTVYASLLADGAVPRVVGSRLGSLPANGGA----------------------APAVEISLETGPSVLFDGVVIADGAAGAERLAQDANALEFVRLQYRHGKPILALGAGKELLSKA-------GI--------------------------------------------------------------------------------------- +--TRRVAILVC------------EGVAQKSVFAVYNDLLQEGAVPRLVGARLGKIKTAEGT----------------------TLDIEITLEAGPAVLYDGVIIMQGDA---SLPRSADPLEFVRQQHRHCKPIYAIGGGM-LIAAA-------GI--------------------------------------------------------------------------------------- +--TRTVAILTA------------PGTDADEAQAMYDYLKDQGAYPTLIGVNLGEQ---D--------------------------NITSTYMHTASVLFDAVYVPGGSKD-LAQFPYDEPKMFVIDAFRHCKPIAATSEGVDFVNDA------------------------------------------------------------------------------------------------ +--TRTVAILTA------------PGSDNSDAQAMYDFLEKKGAYPAFVG-----IRG--QD----------------------GLNITESYLTTSSVLWDAVYVPGGNK----F-PYDEPKMFVLDAFRHGKPIAASAEGSKLLEYA-------GV--------------------------------------------------------------------------------------- +--TRTVAILTA------------PGTNTEEAKAMYEYLKSEGAYPEYVGVGLGDQ---D--------------------------EVTNTYTTTSSVLFEAVYIPGGPEN-TSLFPYEEPKVFVLDAFRHGKPIAASSDGFDILKWA-------DV--------------------------------------------------------------------------------------- +--TRTVAILTA------------PGTDADEAQAMFDYLKDQGAYPTLIG-----VNG--QD----------------------GLNITSTYMHTASVLFDAVYVPGGSK----F-PYDEPKMFVVDAFRHCKPIAATGEGVDFVNDA-------IS--------------------------------------------------------------------------------------- +--------------------------------GPYDILTKSGFVIEVAAEKEITKSIEGVLVER-------------------TVVLDNKLIDHVHTKYDLLVVPGGGSDAVNMRLIAAFANTLSKFKDDRRVLLSICTGAAFPANL-------GIFNDRYCTTHWAF--------------------------------------------------------------------------- +-----------------------------------------------------------------------------------------------------MILPGMVN-IGPALQDEKLISFLRSLDEQDILIAAISSAPLLLAKA-------GLLNDTKFTG--GIWQNFFDYFEFLS--------------RENFKS------KVLVQDKQIITAIGFA-HQEFARK------------- +----------------------------------------------------------------------------------------------------------MID-FKLVLRDKELLTFLAGLNEESILIAAISSAPILLAKA-------GLLKDKTFTG--GIWQNFFDYFDFIP--------------KENFKP------LSVLKDQNIVTAIGFA-HQEFART------------- +----------------------------------------------------------------------------------------------------------MSD-FTSALKDNTLIQFLKQLKGKSILVAAISSAPILLSKA-------GLLENTTFTG--GIWQNFFGYFDFLS--------------RENFIP------KAIHQDKNIVTAIGFA-HQELAKK------------- +------------------------------FMPPELKAQALDMEFHWVSETDGPCRLTSSI----------------------SMNPTDTFETCP--PLDVVLMGAHHP---SYTPSAAELAYIRKAYDASSAFLTICGGLMAPLQA-------GVLDGKTVTAPRFMLGRLRE-----------------TNPSSTWL------EKRWVRDGKLWTSGALLNGADMVSA------------- +-SSKKVEVLLL------------PGFQELEFWYPVLRLREAGVGVSVVGRDDTQTVFS-------------------------RLGYPVVAEQADGGAGDLLIVPGVVG-EPDADTRERALSSIRAAHARGALIAASGSSVALLAEA-------GMDTAKTITA------------------------------------------------------------------------------- +-SSKKVEVLLL------------PGFQELEFWYPVLRLREAGVAVTVIGRDDTQTVFS-------------------------RLGYPVVAEQAEGGAGDLLIVPGVVG-QADAATREQALASMRAAHARGALIAASGSSAALLQEA-------GVDPAKAITA------------------------------------------------------------------------------- +----QALVVIPSA-----------GFDEESFQTVVRELTLYDIAWTLAAPD--PV---SQLISDT------------------EVQSLDSISDM-ITNETAIIVIGGSD-MSSLFSSEPLNRILEKGSQAGSICAGIGNGTLALANA-------GILNGVKVSAPDENSRVF------------------LEQSGAIPDQ-----AEGVITD-TIITAQGPASA------------------- +--KKKIAILAY------------DDMDIMEYSIVFNIFAKINFKIHSVSSKAK-IKS-NNI----------------------DITVDKI-VGTDIFNPNIVIIPGGVG-ASIATNDSILMNYIRKRYNECDYITAFSNGIYFLDKF-------NDINGVAIPESKWK------------------------IEGAIEI------KRSFVDNGKLMFASNMIGIIELCVE------------- +--KKIINILTY------------DNINIMEYSIPFNIFSKANFEVHPISNKSQ-IET-ENI----------------------NVSVKDI-INNNIYKPNIIIIPGGKD-VKSAAKDSVLMNYLKFIYSNCDYIITFSNGIYFLNEF-------NDLEGITVPKSEWR------------------------IEGTIQI------KKAFVDNGKLMFASNMIGIIELCTE------------- +--ERKFGIFIY------------DKMVVSTVISFLEIFHDINISVELIGTQRN-IIKDKIY----------------------DIKFENI-KSVEEVDLDVIIVPGSKS-NKFYEND--DFEKLLNNINGCETVCVLGNSIIPFIKN-------KFLRGLKAYYSKEWVEFI-----------------KEEIALTSYS------DEDIIDNGRLIMVKKKSCEIEGIKY------------- +--KKYVEVLVL------------DGMNVLDYSMPFEIFNKANFNTSSVSFVDK-IKGNSGI----------------------EIK--RS--AGSEQKPNIIIIPGGID---TKENSKNIIDYILKNYIECDYICAFSEGISYLVKC-------KELNGIFVPNGKWIK-SL-----------------LDEKRTLRIL------NKNYIDNGKIMLSTNLMGTLELCLN------------- +--KKNVCCVVY------------DGVDFMEIASTFELFNLLNFDLYTVGEQN--VKASNGV----------------------DIIPRRG--IENELSSDILIIPGGSS-FNNVLNDSKLCSFVKNEYKSSDFIIATGEGILLLAQC-------GLIKDHTIAAPNFIVDKV-----------------QVLSPSTTIS------GKSFVDNGRIVTARGGKSSMEGTFK------------- +--KANVGMLMI------------NDMNVLDFTMAKELFEKANFNVYGISIDKS-IEVSRGL----------------------KLN--IE-LENNNKTPNVLIIPGGKG-IISREKGEQVINHIINYYNDCDFICAINEGICYLAHC-------KKLDGVVVPKGNWID-QL-----------------KDRKEDFRVV------KRNYTDNGKIMLSANLMGSLELYLN------------- +--KRNVQVLAY------------DNMDIIDYSIPFKIFKRANFEVISISYDGI-NNLQNNI----------------------QINSE-S-FKDNNLEKEILIVPGGMG-ALEVLEDEVIVKYILSNYNNCDYVLCFNLGIHFLNKC-------NIIEGLFIPKSKEFD-LN-----------------RLNISKHKLV------DKNFVDNGKIVISSNIVGNIESCLN------------- +--VKNVSFIIY------------ESINITNYALFWDIFNEVNFNFEIISLTDK-TNYSNNL----------------------KLELDS--SNFSVLDSNIIILPNSTS-MENIIQNENIIKSIVEVYNQCNYICAIGNSIAILEQI-------KSLTGMSVPNIENLSKLI-----------------KSKLNKIKIV------NKNFVDNGKIMIASNLMGMIEMILA------------- +--MTQIAFVTY------------PGVTALDLVGPYEVLRHPDADIRFVWRETGPIATDSNVL---------------------LLGATHTFGE--TPNPDIVVVPGGTPTVAVQARDQELLEWLRA--------------------------------------------------------------------------------------------------------------------- +--SKNIAILIY------------DQIEIQDFAGAFEIFSAARFNVFTVAADKAPITCNSGVTPT------------GGKSSSFKITADHTLDC--HPKIDTLYIIGGPGILDKEAQQPFLTEWISIVSEEADYVAGTCSGALLLVLS-------KQLKNMNVTTHHTRFEQMDALSEKY-------------SLGLNVLD--TRNGEQYIHNSKFMTSGGVTCGLALSLH------------- +-----------------------------------------------------------------------------------------------------------------LKNCKSLESMVKKQDEEGRLNAAICCAPALAFGT------WGLLEGKNATCYPAFMEKLST--------------------CAKSV------ESRVEVDGRIVTRPGTT--------------------- +----------------------------------VDVMGSRLFDIDVLSADGAAVRSFGDM----------------------PVPATAALTDA---AYDVVIVPAQFAPATLDAEEAHIADWLRTRYEAGALVVGMNAAPL-FAKA-------GLLDGCRATGLASERAWF----------------------------------------------------------------------- +-VNKRIGILVPQH------------ANDFEIAVLNLILKEAGAFVTLVSLGKQLTMQMQTLN---------------------KIVCDELIEKCNLSKFNFLILISSPSLRQETPRVPKINYFLNSFFEPNKFLIALNNSCCFLNEN-------GLIDGYKVTCNDKFCQID----------------------NNLKNQ-----KEEIIVDRNLVTTNSSHSAIKVA--------------- +-MNKMVGIIVPQY------------ANDYELATFNLFLKKAGFYVTLISLTKQLIIQMQSMN---------------------KIVCNELIEKCNLSKFNFLILISSQNLTLQSQKIPKLNKFLNDFFEDNKYLIAINDAPLYLNEL-------NLLKDFKFTCNNTLNKKL----------------------GKNCLC-----DKNIVQDCCLITANDSICALKIV--------------- +-----------------------DGTEIHEASAILVHLSRGGAEVQIFAPDVPQM---HVIDH--TKGQPSEGESRNVLTESARIAKITDLANLSAANHDAAIFPGGFGAAKNLSVNKEVERVLKEFHQAGKPIG------------------------------------------------------------------------------------------------------------ +-----------------------DGSEIRESVLTLLALDTANIEYQIFAPDEPLF---HVIDH--VSGEINMAERRNVLQEAARIAEISLLHKLDANEFDGLILPGGFGVAKNLSVHGTVVSILKAFHQSKKVSV------------------------------------------------------------------------------------------------------------ +--------------------------------------------------------------------------------------PNVTYDTC-PRDLDIIIIGGPLPS----HRPPPADRFMKEAWLQTRVWMTTCIGSMWLAST-------GLLDGKKATTNRSLLGAA-------------------KQANVEWLD-----QKWAITDGELWTAGGAAVGTEM---------------- +------------------------------------------------------------------------------------LRAHMDFKEARLKEFDVLIIPGGGVDPEPLGLIKAYSDLQKKDPKKERTLMSVCTGSLLLAQQ-------GLLSGLSATTHPDYYAKF----------------------------------------------------------------------- +-----------------------------------------------------------------------------------TIKPTTTCATCP--KLDYLLIGGPYP-EFFLNVPDVFANFIRERVDEVEGVFTTCTGGMVAAMV-------GVLDGKTATTNHQYLAAA-------------------KKLDVNWS------SKQWVVDGKFWTAGGALAGMDM---------------- +-----------------------------------EELRAQAIDVVFHWVSEAGPATPSRLNCGI------------------TLVPTDSFEDCP--HLDIVVMGAHLAG---YVPTATELAFVRRTYETCSAFIAICGGVQVPLMA-------GLLDGKKATGPRFLLDMFRQ-----------------QAPATEWL------EKRWVRDGKMWTSGALLNGLDLMHAFAHEH-------- +------------------------------------------IDIRYVSETGE-GSFPVTAGS--------------------RMPVTNSFA--NAPQFDLILIPGTFS-SSSLPASASTFLTTQCLNPSLLAIMSISSGIAYLVQA-------GSLHGTRAAAPRSLLPVLQR---CYP--------------HTHWLY------AAWTRHGKVWSSNSPVSALHMVAE------------- +------------------------------------------IDVRYVTASGE-GSFPVSSGG--------------------RIPVTNSFQ--NAPQFDILLIPGSFS-TTPLPPSATLFLNCQCARPNLIAIISIVSGILHLAQT-------GICNERRAAAPRSLLPALKQ---RFP--------------EISWRS------TPWERHDKLWSSNSAVSALDMMRT------------- +------------------------------------------IDIRYVSMTGE-GSFPVTAGS--------------------RMPVTNSFI--NAPQFDILLIPGTSI-LTNLPPPASSFLTSQCLNTNLLAIMTISSGIAHLVQA-------GSLHGTRVAAPRSLLPCLQH---RFP--------------ETEWQY------APWARHGKVWSCNSPVSGLDMVVE------------- +------------------------------------------IDIRYVNVTGE-GSFPVTSGS--------------------RMPVTNSFA--NAPQFDILVIPGSFS-SSELPAEASSFLTTQCLNTNLLAIMSIASGISYLVQA-------GSLQGTRVSAPRCLLPALQQ---KYP--------------EAQWQF------SSWSRHGKVWTSNSAVSALDMVAT------------- +------------------------------------------IDIRYVSVTGE-GSFPVTAGT--------------------RMPVTNSFA--NAPQFDIVVIPGSFS-LSELPTEASSFLTSQCLNPNLVAILSIGSGISHLVQA-------GSLHGTRAAAPRSLLPTLQQ---RFP--------------ETQWQY------SPWARHGKVWTSNSAISALDMVSA------------- +------------------------------------------IDIRYVNLTGE-GSFPVTSGT--------------------RMPVTNSVA--NAPQFDVLIVPGSFS-LNEILASAATFIAAQASHPDLIAIMSIASGVTHLAQA-------GVLHRKRAAAPKCLLAVLES---KYP--------------QTFWQR------SEWARHEKIWSSKSAASAIDMVAT------------- +------------------------------------------------------------------------------------------------------------------------IGWLKQRYAEGAVLASACSGAMLFAEA-------GLLDGCEATTHWAWCDVMRH---RFP--------------KIKVHP-----QRALVVSQRLIMAGGGTSWTE----------------- +---MHIAILTF------------DGFNELDSLIALGILKRPGWKVSIACPAARV----TSMN-------------------GIVIEAQATLED--ASRADAVIVGSGMK-TREVVADTGLMSELR-LDPSRQLLAAQCSGTLVLAKL-------GLLDGVAACTDLTTRP-------------------WVVEAGVDVLN-----QPFV---------------------------------- +--MRRIVIVGY------------PEVELLDVACVADTFDTANYSIEFATLGAQPASSGSGLV----------------------LAGQHALERI-TGPLDTIVVSGGLG-HERAADDPVLVAHVRRLARESRRVSSVCSGA------------------------------------------------------------------------------------------------------ +--SRKVAILVA------------DGVDSKAVEAMKAALTAEGAHAKVLGPTSAPVKTADGK----------------------SLPVDASAEGLPSVAFDAVFVPGGKASIEALKGDGVALHFILEAYKHLKAISFAGEAKELLSLL-------RL--------------------------------------------------------------------------------------- +--SRRIGIIVA------------DGYDPIAFNAIYGAIQGAKAIPIVIGTHRSETESQSGK----------------------GIVPDHHLEGQRSTMFDALFVPGGKQAIETLSKNGRALHYIREAFGHLKAIGATGEGILLVEKAL------QL--------------------------------------------------------------------------------------- +----MVAILLN------------DKVNAAELLTILQALKAKGVHAKLLYSRMGEVTADDGS----------------------TLTIAATFAGAPSLTVDAVIVPCGN--IADIESCGDARYYLLEAYKHLKPIALAGDARRFKALL-------NI--------------------------------------------------------------------------------------- +----MVAILLN------------NQVKSADLLAIMQALQAEGVHAKLLYSRMGNVVADDGS----------------------TL------------TVDAVIVPCGN--LADIVTNDDARYYLFEAYKHLKPIALAGDARQFKATL-------NI--------------------------------------------------------------------------------------- +--QRKIALLVH------------DGVNASSIDDIKIWAEAEKAIVETLAPKAAPVKSSDGN----------------------EIPVDGRQNGEPSVTYDAVIVVDGN-NLEVFKADGVSKHYVLETYKHLKPIVFLGDKCALIDEF-------QL--------------------------------------------------------------------------------------- +--TRKVAFLVA------------DGVSRASVDVMKKALEAEGAEAVLISTHTGTVKFKEGG----------------------EAEIQHTYLTEASVCYDAFYTPDGD-SVAALEDEPDYIHFINEGFRHCKALAFAKGAEKLIAES-------YI--------------------------------------------------------------------------------------- +--QRQIAILIE------------NGVEHASLAALYGALTDAGAIVHLVGTRIGIFVGTNGE----------------------NIAVNQSLEHTPSVLFDALILPDGNKAVHALATSLDTSEFIKNLYRNGKTILALGSGRQLLDRA-------AI--------------------------------------------------------------------------------------- +--GRTVGILIH------------DGSDAATIKAVRKAAEAAGATVKIVAPKLGGAKLSDGK----------------------QLAADGQLAGTPSVVFDAVAVVLSSEAAKALTRESAALDFVSNAWAHLKAIAFDDGAQLLLKAG-------NV--------------------------------------------------------------------------------------- +--GRVVGILIN------------DRSDAKAVAAVVKAAEAAGSTVKIVAPKVGGAVLSSGT----------------------KMAADGQLAGTPSINFDAVAVILSEEGAGQLVSDAAAVDFVRDAFGHLKAIALDDGGRALFDAS-------GL--------------------------------------------------------------------------------------- +--GRKIGILFD------------EGSDKAEIDKLVAAIEKAGGRAMLIAPKVGGIAVKG-G----------------------TLTADGQLAGSPSVLVDAVALVLAKDAAERLAADSAAIAFVLDAYAHLKAIGHTPGAQPLLDRA-------GV--------------------------------------------------------------------------------------- +--GRKLGILAT------------DGADAALLDALIGAVENEKAAFELIAPKVGGFTASDGK----------------------RIAAHQMLDGGPSVLYDAVVLLPSAEAVADLIDVATARDFVADAFAHCKYIGYAGAAVPLLERA-------GI--------------------------------------------------------------------------------------- +--GRKIGVLVA------------NGTDAQVLKGIRHAAEKEGAMVELVAPTVGGFEASSGD----------------------WIEADHMIDGGPSVLFDAVALVLSDEAADRLTREAAARDFVADAFAHCKFIGFTAGAMPLLAKA-------GI--------------------------------------------------------------------------------------- +--GRVVAVLLN------------ERTSAQDLVQLLQALQAQGVHSKLLYSRMGEVIADDGS----------------------PLPIAGTFAGSPSLTVDAVVVPGGD--LSALSQSGDARYYLLEAYKHLKPILLAGDARQLTSVL-------HV--------------------------------------------------------------------------------------- +--GRVVAILLN------------DEVRSADLLAILKALKAKGVHAKLLYSRMGEVTADDGT----------------------VLPIAATFAGAPSLTVDAVIVPCGN--IADIANNGDANYYLMEAYKHLKPIALAGDARKFKATI-------KV--------------------------------------------------------------------------------------- +---------------------------------------------------------------------------------GFALRTPYGLDDL--AGADTVVVPSVPDPEEGRPLPSGLITALRRAHDERARVVSLCTGAVALAEA-------GLLDGRRAAAHRTHTARL----------------------SGRY--------PRVRVDGDVLTSAGLTAG------------------- +--MKKLLIVNVGSA--PESQLNKFGDFE-------LWAKQ--LEIEFHD-GIA-----------------------------------NPLPK--PQVLAGVIIMGSLSMTEETNWMKRLAAEIVQLAEHRIPTLGICFGHQLISYA----------FGGDIDFNPNGLE------------------------------------------------------------------------- +--MKRLLIVNVGSA--STLLVEKYGNFE-------HWAKS--LVVEFHD-GTH-----------------------------------KPLPP--LNSLAGVIIMGSPAMTQQLPWMKKLEVDVLRLAENSIPTLGICFGHQLIAKA----------FGGDVAENPKGLE------------------------------------------------------------------------- +--MNKILILKTGST--FPELKRQKGDFE-------DWIMAPQSLFQICNLEKV-----------------------------------LHKVD--LQTIKAALITGSHAMTERPVWLKKAISLIKEIRARCIPLMGICFGHQLIAAA----------FGGKVADNPRGAE------------------------------------------------------------------------- +--MKRILLVCTGAP--PAAIAARWGAFD-------AWFER--GRAEVERADAR-----------------------------------APLPA--VGGFDGAILTGSLDSTAWAPWMQATAAWALAAA-RSRPVLGVCFGHQLLARA----------LGARVERRPAGPE------------------------------------------------------------------------- +--MGHIAIIEAGRT--FPPMAAQLGDFS-------DWMAADCDRLQVIPAFTD-----------------------------------AALPA--PQSLQGVVISGSHAMTDACSWMERLADWLVEVVEASVPVLGVCFGHQLLARA----------LGGEVGYHPRGRE------------------------------------------------------------------------- +PRRPTVLLALLGDP--GPATRAALGGFE-------RWFRE--PAADVRLVHRQ-----------------------------------GVRDA--AATADGIVVTGSYASTERAPWMITLGDALLEAS-ERIPVLGVCFGHQLLAAA----------LGGVVERNPRGPE------------------------------------------------------------------------- +MSEKVLLVIQLGQP--PEGIASQVGQQG-------KWFSDNSQPIQVVRPDRG-----------------------------------ESLPP--FDTLAAVIISGSWSMTDRLDWSEYTAGWLREAYYAEVPLLGVCYGHQLLADA----------LGGKVGDNPNGKE------------------------------------------------------------------------- +--MQKKLIIRTGRV--YAELRGELGDFD-------DWIRRDGDSWQVIDVQAG-----------------------------------EALPA--VTEVAGAVITGSAAMSERAPWSEATAAWLRSAHAANVPLLGICFGHQLLAAA----------LGGEVGYHPQGPE------------------------------------------------------------------------- +--MKKLFIIKAGIT--FADTKKENKDFD-------TWVIES-LDIEVIHIQEK-----------------------------------IYFPN--IDEVAGVIITGSHSMTDEEHWSVAIEKWIPTLIQNDIPLLGICYGHQLLGKS----------LGGVSGYHKAGIE------------------------------------------------------------------------- +--MKPVLIIKAGST--YPELIEHYGDFE-------DWIARR-CAVQVCDVREP-----------------------------------VPLPS--PDRIAAVVITGSHAMTEQAPWMVRLTDWLDDVITHALPVLGICFGHQLLAKL----------LGGEVGDHPQGME------------------------------------------------------------------------- +PSSRPILVLKTGST--FDHLIPARGDFE-------HWTARAPDQWICADVRRG-----------------------------------DPLPD--PAILTGCVITGSHDMTDDADWMLTTGRWLAGAVDAGLPMLGICFGHQLMAHA----------LGGRADYHPDGPE------------------------------------------------------------------------- +--MKTLLIVNVGQA--PQAQLEKFGDFE-------EWALRQGIHIEFHD-GVQ-----------------------------------HALPN--FDTLAGVIIMGSLAMSEKKPWMLRLSDEIVQLVERQIPLLGICFGHQLIAQA----------LGGVVGYHPQGLE------------------------------------------------------------------------- +--MKSFVIIKTGST--LLPIRQRFGDFE-------DWMSESGAP--VIDAAGG-----------------------------------EALPL--PETLSGAIITGSPAMTDRAGWMQSLAVWVREAVSEAVPLLGVCFGHQLLAQA----------MGGHVDYHPQGRE------------------------------------------------------------------------- +--MKTLSIIKTGTT--YPEIKAEHGDFE-------DWFIRPGLRLEVHDVASG-----------------------------------AP--L--PEHSDGVLVTGSPAMSERADWSERTAAWLARRIAGDLPVLGVCYGHQLLAHA----------MGGTADYHPDGRE------------------------------------------------------------------------- +--MKPLLILKLGAP--KADIIARLGEYS-------DWIARVQHPVRVLDIIGG-----------------------------------EALPA--VDSAAGVILTGSAHMPERQLWSEATCAWLQQAVPAGLPVFAICYGHQLLADA----------CGGAVGDNPRGLE------------------------------------------------------------------------- +---MRLIVLRTGNA--APEVAARRGEFF-------SWIRRAWGEWHEHDVTD------------------------------------HPLPH--AGEASAFIITGSSSSTERAPWMLRTEALIRDIADAKTPLFGICFGHQIVAQA----------LGGAVAKNPRGRE------------------------------------------------------------------------- +--MKPLLLMQTGDA--PEAVRRELANFD-------QMFLQAADRVQTVHLPAG-----------------------------------EPLLP--PENYCGVVITGSPAMTEQLPWSEQAAAWLRQAMQIRLPIFGVCYGHQLLAYA----------LGGEVGYHPQGME------------------------------------------------------------------------- +QNSNHLLILQTGDA--PESVRREHGNFD-------RMFILNEARVQVVYLPGG-----------------------------------ERPEA--PETYAGVMITGSEAMTDKLPWSEYAADWLRRAVAGNTPVFGACYGHQLLAYA----------LGGKVDYHPDGME------------------------------------------------------------------------- +RKRLPLLIVQLGRP--PEDLVRQVGEQA-------DWFAS-DEALLVARPHLD-----------------------------------EPLPA--ADRFRGVVLSGSWDMTDRQAWSERTGDWLREIVPAGKPVLGVCYGHQLMADA----------LGGQVDDHPDGLE------------------------------------------------------------------------- +SHTQPLVVVKLGST--FPGLSSERGDFE-------HWFRDWDLPVRILDAAAR-----------------------------------PALPE--PDALAGVILTGSSSMTDRLPWSERLRPWLARIVAEGLPVLGVCYGHQLLADA----------LGGEVGRRSQGVE------------------------------------------------------------------------- +SNSKQILIVKLGST--FPELSKKLGDFE-------DWIQDK-YSTKVIDAKSL-----------------------------------PILPE--PSLFIGIILTGSSAMTDKEEWSERLKPWLIKCMNQKTPILGICYGHQLLADT----------FEGKVESRQDGVE------------------------------------------------------------------------- +NNSKPIAIIKTGST--YPQISNHYGDFE-------QWIASA-APVWVVDVSQG-----------------------------------DHLPE--ASALAGLVITGSHAMTDQADWMTTLSHWLYRAIHQTLPVLGLCFGHQLLAQT----------LGGEVADNPVGIE------------------------------------------------------------------------- +MQPVNIALLKMGDL--RK---YSSPDYD-------ELIISDRKHFSVYDIPDG-----------------------------------NKVSS--HVKPDGIIISGSSLMTDKLPWKEPVCEWLQEQIADDIPILGICFGHHLLAQV----------LGGKIGDNPEGIE------------------------------------------------------------------------- +SADRPLLILKTGRK--TPCLNPLPGDYE-------DWIAADPAQVRVVDAAAG-----------------------------------DMLPD--LHRISGIAITGSGAMTDQALWISRASEWLAQAVEQQVPVLGICFGHQLLAHA----------LGGRVGYNPQGVE------------------------------------------------------------------------- +MRRPKLTVLKTGST--LPGLLNRRGDFE-------DWIRQTGAEVRVVDAQAG-----------------------------------EPLPP--PGRQDGVVVTGSPSMSRREPWSEEAADWLGSLAGTPIPILGICFGHQLLAHA----------LGGEVGRNPAGRE------------------------------------------------------------------------- +--MKKLFLVKTGKT--FPALIKRRGDFD-------QWFIQSPDHIEIVEVFEG-----------------------------------EPLPDE-LDDVAGVLVTGSPAMTDRERWSELTAKWLCQVHQSSIPLLGICYGHQLIAHA----------LGGKVANNPNGFE------------------------------------------------------------------------- +MASKPILIACAGRT--FPGISARLGDFD-------NWIAD-HLPVTTLDIREA-----------------------------------DTLPA--ADTLAGVVVTGSHSMSDREPWSERAADWLRALIGAGVPILGICYGHQLLAHA----------FGGRVDYHPGGIE------------------------------------------------------------------------- +--MKPLLIVKTGTT--FSSIRQRYGDFD-------DFILSITHDAIIAPIFET-----------------------------------LWLPK--LDIISGVIITGSHSMTDREEWSEYLAEWLRNIPAGSLPVLGICYGHQLLAHA----------FGGEVRYHPQGVE------------------------------------------------------------------------- +---MSFIIIKTGST--LESLIQKKGDFE-------DWFLQA-EKVQIINVQNN-----------------------------------QSLPA--LSGISGVLITGSHSMSNREDWSEKAAIWIKDAVAQNIPVLGVCFGHQLLAHA----------LGGKVGPNPKGLE------------------------------------------------------------------------- +MSQTSFIIIQTGTP--PEDIRQKYGDLP-------DWFSQPLQEIEVVRVFEG-----------------------------------QPLPA--PDPSRLAVITGSWAMTEKLSWSELTAEWIRQAMAINMPLFGVCYGHQLMAYA----------LGGEVRYLDCIRE------------------------------------------------------------------------- +--MLPILIIKAGGT--FPETRKKFGDFE-------DWTMHLSDQVMIVDFRED-----------------------------------VPLPE--MGAFSGAIMTGSHSMTDPDPWILRTEAYIQRIMEENVPFLGVCFGHQLLGRA----------AGGKAGNNPKGKE------------------------------------------------------------------------- +MTRNRLLLVQTGTP--PAAIREEHGDLP-------HWFRTWQAQLTAVRVFED-----------------------------------EPLPA--PDRQTVAVLTGSWAMSDRLAWSERTADWIRQAVAIGMPLFGVCYGHQLMAHA----------LGGEVAYHPAGRE------------------------------------------------------------------------- +PAPRPIVIARTGGT--FPALRERLGDFE-------DWVQATAAPVLTIDAAQD-----------------------------------EGMPE--PASIAGVVVTGSHAMTDRAPWSEALGGWLARAVAAQTPVLGICYGHQLLAHA----------LGGDVADHPGGWE------------------------------------------------------------------------- +--MDTLLIIKTGTK--IDSLQDFPGDYE-------DWIAAP-TQTKVVDVQAG-----------------------------------DPLPA--PGDVVGVVITGSGSMTEEAPWIQQTADWLAHAVSAGVPILGICFGHQILAHA----------LGGRVDWNPRGIE------------------------------------------------------------------------- +-MNKPILIVITGET--FASISAAHGDFA-------DWIEASPLAIERFDARGA-----------------------------------AALPD--VDDYAGIVLTGSHAMTAREPWSERLGHWLADCAARVTPMLGICYGHQLLAQA----------LGGEVGDRDRRFE------------------------------------------------------------------------- +--MPTLLLLKTGST--FPELVSQKGDFE-------DWILQTRRDVSIVDVTQQ-----------------------------------EPFPA--YDTLSGIVITGSHDMTDGHAWNERTARWLRRAIEGRIPILGICYGHQLLAYA----------CGGEVADNPHGRE------------------------------------------------------------------------- +-MQGRRCIIKVGGS--FGALTACRGDFE-------DWIRADGRRWQVIDASAG-----------------------------------EALPD--GAELAGVVITGSHAMTEAAPWSLSVEQWLAGLLARRVPVLGICYGHQLLARA----------CGGEVGFNPRGLE------------------------------------------------------------------------- +--MKSFLIIKTGGT--FPDFASEHGDFE-------HWVAALADECNCVDVRTG-----------------------------------AILPD--PTHYDGCVITGSHDMTDDLEWIHGTGDWLYSAGETGLPILGICFGHQLLAMI----------HGGQSGFHPQGPE------------------------------------------------------------------------- +-MTKPILIIKTGKT--LTSIPAEKGDFE-------DWIISSRQETIIAEVYKT-----------------------------------FALPN--FDEISGVVITGSSSMTDHHDWSEKTAAWLVDAVRQELPILGICYGHQLLAYA----------LGGEVGKNPKGCE------------------------------------------------------------------------- +--MKPILIIKTGQA--LSSIPAEKGNFE-------DWIISISEQAIIAEVYNG-----------------------------------FDLPP--WDEVSGIVITGSSSMTEGHDWSEKTAKWLVNGIKKDLPILGICYGHQLLAYA----------LGGEVGKNPQGCE------------------------------------------------------------------------- +-MKNAMLIIRTGQP--PAPVGARLGQFA-------DWLRRCDRAWQEVHVAAG-----------------------------------EPLPP--VANCAGAVITGSPAMTDHLPWSEATAAWIREAVAAEVPLLGICYGHQLIAYA----------LGGEVGYHPDGPE------------------------------------------------------------------------- +VSSRPLLVVQMGYP--PAVLQESIGDQA-------AWFAQPSCPVRVVRPFLG-----------------------------------EILPA--AHELSAVVISGSWSMTDHEPWSDATGAWVRMLMDNRVPLLGICYGHQLMSWA----------LGGEVGYHPEGPE------------------------------------------------------------------------- +MEQKSLIIIQMGDA--PKPLRDAHGDVP-------HWFCRAPEEVDVVRVFEG-----------------------------------ETLPA--PDARRAAIITGSWAMSDRLPWSEKTAEWIREAIAVEMPLFGVCYGHQLMSWA----------LGGNVEYHPQGRE------------------------------------------------------------------------- +MEQKSILILQMGNA--PQTMRDAHGDVP-------LWFCQELDDVEVIRVFEG-----------------------------------EALPA--PDPRRAAIITGSWAMTDRLPWSEQTAAWIREAMVMEMPLFGVCYGHQLMAWA----------LGGDVQYHKDGRE------------------------------------------------------------------------- +---MAILIVETGET--PGKMPEKCGTIA-------QWFENIGKKAETVRPYRG-----------------------------------EALPV--ATSVAGAIITGSWSMTDREDWSEKTAEWIRELLFFDIPVFGVCYGHQLMAHA----------LGGLVGDNPEGGE------------------------------------------------------------------------- +MTRKPLAIIQMGRP--PEDLRQAQGEQS-------DWMLAPDLPVRVVKPHDD-----------------------------------EALPA--WDDVSGAVLTGSWSMTDREPWSERTAEWLRGAHDARLPLLGICYGHQLMAHA----------LGGVVDFHPQGRE------------------------------------------------------------------------- +MTNKPIVLIQAGTA--PDKIRKEVGDYP-------SWFCSDLENLEIVRVFEG-----------------------------------EVLPS--PDPARAAIITGSFAMTDRLLWSETTAQWIRDAMTVEMPLFGVCYGHQLMAHA----------LGGRVGYHPAGQE------------------------------------------------------------------------- +--MHPLMIVSTGTP--PPEIRARHGDYA-------DWFLHPRAQALVVHVDRG-----------------------------------ESLPA--PETIAGAVITGSVAMSERAEWSERTAAWLRTALHANLPLFGVCYGHQLLAHA----------LDGRVDYHPQGRE------------------------------------------------------------------------- +RSTKPFLIIQPATS--FDALCAFRGDEV-------RWFSESDRDITAVKVYQG-----------------------------------ESLPD--PRNVQGAIITGAIDMTDGHQWIETAAQWVREAIVAETPVLGVCFGHQLIAHA----------MGGRVGENPRGSK------------------------------------------------------------------------- +----------------MPATCAVHGDEV-------AWFSAPRDEILAIKVYQD-----------------------------------EPLPD--PAEVRATIITGAIDMTDGHPWIERTAAWARDAMAHGAPILGVCFGHQLLAHA----------LGGVVDDNPRGAM------------------------------------------------------------------------- +--MKTLLIVNVGSA--PESQLNKFGDFE-------LWAKQ--LDIAFHD-GIN-----------------------------------HPLPK--PQNLAGVIIMGSLSMTEEADWMKRLAAEIVQLAEFNIPTLGICFGHQLISYA----------FGGKVNINPNGLE------------------------------------------------------------------------- +METGKLLIALCGDT--HPAILEEFGNFD-------SWFIDMGISTHLWNTHMH-----------------------------------HDAP---EGDFIGCVVTGSPAMTDRAQWSEDLGRWMRLAIERGLPLLGVCYGHQLLADA----------LGGVVDYQPDGRE------------------------------------------------------------------------- +SPKARVVILKTGTT--YPQIQAQFGDFD-------AWFVRGQLDVTVVDVTQA-----------------------------------PLPGQ--PGDWQGILITGSPAMSERAAWSEATADWIKQAVEADVPLLGVCYGHQLLAHA----------LGGRVDYHPKGRE------------------------------------------------------------------------- +AAEIRIAILKTGST--YTELERDFGDFE-------NWFEEPAVRTTVIDVTGG-----------------------------------KPDSQ--PSEWDGIVVTGSPAMSDKEAWSEDTARWLAQAVTNEVPVFGVCYGHQLLAHA----------MGGKVGYHPNGRE------------------------------------------------------------------------- +--MIRLLILKTGSA--PAPIAREHGDFE-------DWFVAA-SEVEVVNAEAG-----------------------------------QPLPER-LDPGVGVLVTGSPAMSHRLDWSERAAAWLRKIHAEQRPLLGVCYGHQLIAHA----------LGGRVGPNPAGRR------------------------------------------------------------------------- +PSQKSLLILQTGHA--PEPIRRAHDNFP-------QMFIRDAQQVVIVDLQAG-----------------------------------ERPLP--PENYCGAIITGSRSMTEHLAWSEEAADWVRLGMLQELPMFGACYGHQLMAYA----------LGGEVDYHPQGIE------------------------------------------------------------------------- +ARSSRLLIVQVGTP--PKEIREPLGDLP-------AWFCRPIDEVEVVRVFDG-----------------------------------DVLPE--PNPGSAAIITGSWAMTDRLPWSETTAEWIRDAVAVGMLIFGVCYGHQLMAHA----------LGGRVDFHPDGRE------------------------------------------------------------------------- +SEKLPALLVQMGRP--PVDIRNAVGDQP-------SWFEAPEVELKIVRPFLD-----------------------------------EPLPA--PETFQAAVITGSWSMTEHEAWSERTAEWIKQVVAAGTPLFGVCYGHQLMAYA----------LGGRVDYHPQGSE------------------------------------------------------------------------- +EAREPRLLVVRHHE------GDGAGNWE-------QWLAEGGVRLDAVRAWEG-----------------------------------EPLPE--RLTHDGLLVLGYLPDDARAPWLPGTRALARQALGTGVPYFGICLGGQLLAHV----------AGGEVRGEHGTPE------------------------------------------------------------------------- +QNPAPDLLVVQHTP------SGGPDLMG-------GWLREADLRLEVVRAHLG-----------------------------------EPLPD--ALGDRALLVLGFLPWDERAPWLPAVRHLIGQALRQGTPMLGICLGAQLLAHV----------AGGTVMSRYGTPE------------------------------------------------------------------------- +--MPTLYIVKTGST--FDHIAQSLGDFE-------QWIAEPELPAERLRCYAT-----------------------------------LHYPE--ATDCAGVVISGSHAMTDHAPWMQDLQSWLRPVCDAGVPVLGICFGHQILAHL----------LGGEVGPHPAGLE------------------------------------------------------------------------- +MSVLPFLIIETGQP--VPEM-KRYGRFP-------HWIRVAEQETVAIDVANG-----------------------------------DALPD--PADFAGIIVSGSAAFTDRADWSERSAEWLRHAAHQGMPLLGICYGHQLLAHA----------LGGEVDYNPAGRE------------------------------------------------------------------------- +TSALPVLILHTGDP--DDTLRGRHGDYA-------QMLRHAPQAAHIVRAHAG-----------------------------------ELPRA--PADYRAVLITGSPAMTDREPWSEQAAGWLKQAAAAGLPMFGVCYGHQLLVHA----------LGGEVGYNPRGRE------------------------------------------------------------------------- +---MKVLFVRCGDP--EPSIEAEHGPFM-------KWFAER-VQLEPFDPRVE-----------------------------------KCDASR-LENTDGVILSGSPHSYEPLPWIASLEDLVREAVCNQRPVLGVCFGHQLLAQA----------LGGRVIRNPRGRE------------------------------------------------------------------------- +MSRKQVLLYVVGAP--SEDVRAEFGTYI-------DWFARHDIDVRFFDGHLE-----------------------------------AGVAG--HRGVDGVVITGSAASTVPEPWMDATSAMVQRAHGEQMPLLGVCFGHQVIGAA----------LGGRVIRNPRGWQ------------------------------------------------------------------------- +NLDKPLIILKAGST--FPALAEDEGNFE-------DWIRHL-LPVRVVDPRAQ-----------------------------------AGLPE--PTRLAGVIITGSHGMTEGEPWLPTAEQWLRALVAGEVPVLGICYGHQLLARA----------MGGAVDYRERGIE------------------------------------------------------------------------- +-MSKPLYIFKLGTT--FADTAARLGDFE-------EWTCALNPPLMVVDLLKG-----------------------------------EVLPL--PHECAGVILTGSHAMTDNLPWSVALEQWLPEALALEVPVLGICYGHQLLARA----------MGGTVDYHPQGEE------------------------------------------------------------------------- +MKQPKILIVKTGDT--FADLICSFGNFE-------DWIRQGENQIRLVNAPAF-----------------------------------EVLPE--PGTFSGAVIAGSHAMTQNLDWSLNVEAWLARVVTAGVPVLGICYGHQLLAKA----------MSGKVDFHPDGLE------------------------------------------------------------------------- +--MKKLYIIKAGTT--FSSTLERLGDFD-------DWVKKLAVPVEIIDVVQG-----------------------------------IPLPE--SEQCCAVIVTGSHAMTDNLAWSLALEAWIPLLVADCVPFLGICYGHQLLARA----------MGGEAGYHPLGRE------------------------------------------------------------------------- +GPAAPVLIIHTGDP--IDELRLSYGSYA-------VQLQKSDDETEIVSVFQG-----------------------------------QFLRE--PDQYRAVLITGSPTMTDLVDWSERTAAWLRRAAEHGLPMFGVCYGHQLLSHA----------FGGKVGYNPAGRV------------------------------------------------------------------------- +MKKKPIILIQVGTP--PEDVRRGFGDLP-------LWFSRGPDMLQVVRVFEG-----------------------------------EQLPR--PDSNYSAIVTGSWSMTDREPWSEKTAEWIQEAIRIEMPLFGVCYGHQLMAHA----------LGGIVDYHPNGRE------------------------------------------------------------------------- +GEMKNVLLLKAGDA--ANAVKLSVGDYE-------HWFVEGGCRFDILHVHRG-----------------------------------ARLPDS-AEGYDAVMMTGSPASTQPEPWMERSAEFMVNAAAHGLPVLGVCFGHQLLAYA----------HGARVVRNTHGRE------------------------------------------------------------------------- +QALPKILLIQAGTP--PDELKAKHGDLP-------LWFSTDLENIQVVKVFNG-----------------------------------EPLPE--PDPNRVVVITGSWDMTDKLMWSEETASWIRAI-EADMPMFGVCYGHQLMSYA----------LGGEVDYNPKGRE------------------------------------------------------------------------- +PPSKPVLVIRTGHA--PKPIRARHGDFA-------HWFCLPSSQVRVIDVTAG-----------------------------------ERLPA--PNEVAGALITGSAAMTERAAWSELTAGWIRNAMDAELPMFGICFGHQLMAHA----------LGGRVDYLPGGRE------------------------------------------------------------------------- +STAPALWIIKTGAA--PAPLRAAHGDFE-------DWIAQSALQIRTLDARAL-----------------------------------PEWPA--QDEIAGVVVTGSPAMTDREAWSERTAQWLVRLMQGATPLLGICYGHQLLAHA----------LGGEVAHHPAGLE------------------------------------------------------------------------- +--MKNLYIVKCGST--FDSIKDDFRDFE-------DWIIEK-RDIFVLDVQKD-----------------------------------DFLPN--LGKNDAVIITGSHSMTNEESWSLKLESWLPKLIDEEVPLLAICYGHQLLAKS----------LGGVSGYHETGME------------------------------------------------------------------------- +--MKKIIIIKADST--FEQIIQKHGDFD-------QWVADN-DAVKSVDVRNG-----------------------------------EKLPD--PSDILGAIMTGAHSMTEKQDWSEKTAKWIKRAVDSGTPFFGICYGHQLLAYA----------MGGVVDYNEKGME------------------------------------------------------------------------- +TPPYPLVIVKVGDT--HDTLREGRGDFE-------HWIADQTLPLLVVDPRRG-----------------------------------DTLPA--PGQVAGVVVTGSHAMSHREPWSETTAAWLANVVAHNTPVLGICYGHQLLAHA----------LGGEAGHHPQGPE------------------------------------------------------------------------- +PASKPLLIISAGNT--FPGLRESEGDFD-------DWIAAA-LPMRRIDAQPA-----------------------------------PALPH--PSEVAGVVVSGSHAMTDRAPWSEQLALWMKRCVEAGVPVLGICYGHQLLAHA----------FGGKVDELPGGPE------------------------------------------------------------------------- +SDMACVLIVKTGDA--FPEVVDQHGDFE-------RLFIKAHLELQVWDATRQ-----------------------------------PSAPE--LNTLAGIVITGSHSMSEAEPWSEALKPWLKEVLANDIPMLGVCYGHQLMAAA----------FGGMSDYHPAGRE------------------------------------------------------------------------- +--MACVLIVKTGDA--FPEVVDQHGDFE-------TLFKKTHLDLQVWDATRQ-----------------------------------PSAPD--LDAVAGILITGSHSMSDAEPWSEALKPWLQEALANDTPMLGVCYGHQLMATA----------FGGVSDYHPAGRE------------------------------------------------------------------------- +--MAPLIIIKTGDS--FADVIEQLGNFE-------QLFINGSLSIEVIDARHA-----------------------------------SL-PD--PTTLSGAVITGSHAMTDREAWSEALKPWLQQALAVDLPLLGVCYGHQLMADA----------LGGEAGYHPAGRE------------------------------------------------------------------------- +--MPRLLIVKTGDA--FDDVVRDHGDFE-------ALFRDGEFTLEVYDARHD-----------------------------------GTPPA--LTANDALVITGSHAMSDAEPWSEALKPWLRESRERGVAMFGVCYGHQLMAAA----------FGGDSGYHPAGRE------------------------------------------------------------------------- +KGLRRLLIIKTGTT--FASLCRQHGDFE-------DFIISIPKDVVVAPVYIS-----------------------------------KTIPS--LRDVSAVIITGSHSMTDRQEWSRELSNWLKNIRITSVPILGICYGHQIIADA----------WGGVVDYHPGGAE------------------------------------------------------------------------- +--MKKILIIKAGTT--YDSIREKYGDFE-------DYIINLNEDILVWNAYQK-----------------------------------EKEPD--INDVSAIIITGSHSMSDFEDWSVMLSKWLKDTASGKVPILGICYGHQLLAQT----------FGGTVGYHPRGKE------------------------------------------------------------------------- +--MKKLLLIKTGTT--PEAIKERFGDAE-------EVFLR-VEDTVIWPVYQE-----------------------------------KQPPS--LDDVSGMIITGANASGSRAAWILFLEDWLRANAPRRIPTLGICFGHQLLADA----------FGGRVDFHPRGRE------------------------------------------------------------------------- +--MKKLLIIKTGTT--FPSILKDHGDFE-------DFIINIPSSYCIWSVYKH-----------------------------------EPPPD--LVDIAGIIITGSHAMSDFEDWNVRLSDWLRENLHMAIPTLGICYGHQLLCQA----------LGGQVTYHPQGKE------------------------------------------------------------------------- +PLTAPFLIVETGQP--VASM-RRHGAFP-------HWIRVPRERVVSVNVEAG-----------------------------------ESLPS--TAGLAGVIVTGSGAMTERRDWSEATAAWLGDAARAGFPIFGICYGHQLLAHA----------LGGEVGDNPAGRE------------------------------------------------------------------------- +-----MVIIKTGDT--YDQIGERHGDFE-------DWISNRGLSIVVVDPRSG-----------------------------------GKLPK--FSFVSGIVITGSHATREDVPWIRQLSRWLQQALIHQVPILGICFGHQLLAQC----------LGGVVTARTSGAE------------------------------------------------------------------------- +AIGKKIIIVTTGDP--IPDMIEKRGSFA-------AMIQQLWGDYAGFDALEA-----------------------------------FPHPR----EADAFIITGSASNPNRDDWIVRTEAWLREVVAAGTPTFGICFGHQLLAHA----------LGGECIRNPRGRE------------------------------------------------------------------------- +EKDKKIVIVKTGEP--VPPVLERRGEFA-------VLIEQAWGGYAVFDATGE-----------------------------------LPAPD--APGIAAFVITGSSANPHRDPWMLRCEAWLRDVVRAGTPTFGICFGHQILAQA----------LGGEVIRNPRGRE------------------------------------------------------------------------- +-MGQRALAVMHGVI--PDEQRTILGSLL-------PAMENRGFTVEIVGVDDL-----------------------------------DSVD---LAGLAFICVTGPDSVDEKLNWVAPERQFLQQADAASVPILGVCFGGQILASA----------LGGSVSPSP-RPE------------------------------------------------------------------------- +-MGGRVLALVHGVR--PEWRETVLGSLL-------PAFVDRGFDVVIHDVEDG-----------------------------------PPPP---STGFDLVCVTGPDSADAALPWVEPELRYLSHTVGRQIPIFGICFGAQILART----------LGGSVAPST-RPE------------------------------------------------------------------------- +--MTTALFLAHEDD--RERGRVEAGSLA-------DTTRARGFDVVVAHPG-------------------------------------DDLPD--PTSVDFVTVLGAHAADDSLPWLAPERAYVAAVVDAGTPVLGVCFGGQLLSRV----------LGGVVTRSP-HPE------------------------------------------------------------------------- +MKPARAVAIIHSD-------TDVAGSLP-------DLFAELGIPLEVTPVSA-------------------------------------GLPD--PEGLELAVVMGPESADHRLPWLAPELAWLQAVQARGVPTLGICFGSQLLARS----------LGGQVYRNS-APE------------------------------------------------------------------------- +--MSRAAVVFHERD--HDLGVRNVGSLG-------PALRERGFETTTFSFEGDSR--------------------------------DAQRPP--AEAFDVVVLMGPDAADDSLPWLAEEIEFIDSAVAQGVPVLGVCFGGQLLARV----------LGGTVMRAE-QSE------------------------------------------------------------------------- +--MSRAAVVFHERD--HDLGVRNVGSLG-------PALRERGFETTTFSFEGDSR--------------------------------DAQRPP--AEAFDVVVLMGPDAADDSLPWLAEEVEFIDSAVAHRVPVLGVCFGGQLLARV----------LGGTVTRAE-QSE------------------------------------------------------------------------- +-MNGHVLALVHGIE--ERYWRASLGTLL-------PALQRRGLQVEIKSADEH-----------------------------------APLPP--PSEFRMILVMGHASVDESLEWVDRERRYLRTAIDSEIPILGVCFGAQILACV----------VGGSVALSK-YPE------------------------------------------------------------------------- +TNDPRAVVLVHDGD--PALARRDIGTLD-------AELRTRGFQLDVHSFDH-SP--------------------------------DVAPPR--LSDAQLLVIMGPDAADDTLNWLAPEIAYVQDAIDAQVPVLGVCFGGQLLARV----------LGGSVRKSE-HPE------------------------------------------------------------------------- +-------------------------------------------------------------------------------------------------------------------------EFVTAAAERGVVVAGACTGTFFLAEA-------GVLNGRHATTSWRLGPAFRA---RYP--------------LVDLDT-----RATLVHNSGVATAAAAFAHIDLAL-------------- +-------------------------------------------------------------------------------------------------------------------------EFISHAAASGVVVAGACTGTFFLAEA-------GALNGRQATTSWWLGPAFRA---RYP--------------LVDLDT-----RATLVHDANVATAGAAFAHIDLAL-------------- +--------------------------------------------------------------------------------------PTHTFDT--APPLDVLVLGGGLGSLPT-DQVEPEISFLKAVFPSLKYLFTVCTGSAMAARA-------GLLDGLRATSNNAVWKQ------------------------------------------------------------------------ +--------------------------------IPAEAFTKYDIEFFYMSTTLEPAPTTPSL----------------------RWLPNVTYDDC-PRDLDIVITGGPFPS----HRPAAADRFMKEAFPKTRVWMTTCTGSMWLASS-------GALDGKKATTNRNFLAGAKQ---MYP--------------AVEWVE-----QRWVVQDGEVWTAGGAGAG------------------- +----NIAVVFSGC-GWW------DGTDVHEGVYTMYHLSRNGARFQIFAPNQQQMHMDHMKKQPGSGENRNMMMESSRFSHGQGMMQMQDLSKLDVNSFDAVIFPGGQGVTKNLSLQSDVERVLKDFHRSRKPIGYV---------------------------------------------------------------------------------------------------------- +--------------------FHNFGKDFIENLPPFAISQALDFVTHWVTEDGKTP---GSLSGNL------------------KVIPTDSFTTCP--PLDIVLIGAGQMG---YQATTTEKAFLRKCYAECSAFLSVCGASDALLAT-------DILEGKTATGPLSFLPLF-------------------RQMGTNWV------EKRWVRDGKIWTTGTLLNGLDMIAA------------- +---PSVLIPIA------------HGSEEIEVVTLIDILRRAKANVVVASVEKTGVMASQGT----------------------KIVADKLISDIQESAHDLIILPVI---------------------------------------------------------------------------------------------------------------------------------------- +---PKVLVPVA------------NGTEEMELITIIDVLRRADADVVVASAENGEIVARHGM----------------------RIVADTTLDEAATSSFDLIILPAS---------------------------------------------------------------------------------------------------------------------------------------- +---PQILVPIA------------NGSEEMEAVIVIDVLRRSKANVVVASVEDKEIEASRKV----------------------KLVADMLLDEASKLSYDLIVLPVS---------------------------------------------------------------------------------------------------------------------------------------- +---MQIAVLTF------------DGFNELDSFIASSILRARGWMAHIASPSETV----TSMN-------------------GVMIARQKPLEF--AAEADAVVIGSGIR-TREIAADPAMLARIR-LDPARQLIAAQCSGTLLLARL-------GLVGALPACTDLTTKP-------------------WVVEAGVEVI------DAPFVAHGNVATAGGCMASHYLA--------------- +----------------------------------LELLRNMGAELSFFSP----------------------------------------IHDRELPEADSLYLPGGYPEHVALAANGTMQASIRAHHIAGKPILAECGGMLYLLEALTDVEGVGLLSGE----------------------------------------------------------------------------------- +----------------------------------IRFLRELGAEVSFFSP----------------------------------------LSDKCLPEADALWLPGGYPEAEQLSKNNSMIESIRAFSTTKKPILAECGGFLYCLESLTDLQENGILAGK----------------------------------------------------------------------------------- +----------------------------------LDLLRNLGAQLEFFSP----------------------------------------LHDRELPAVDSLYLPGGYPEHHALAANAPMSEAIRAHHAQGKPLLAECGGMLYLLDALTDVVGEGLLPGE----------------------------------------------------------------------------------- +----------------------------------LDLLQTLGANIAFFSP----------------------------------------VHDTQLPAADAYWLPGGYPELDQLQHNHSMRDGLHAAAQAGKPILAECGGMLALGDTLN-----GLLPGN----------------------------------------------------------------------------------- +----------------------------------IDFLQRQGAEVSFFSI----------------------------------------LNDSQIPDCDALYLPGGYPEAKILSDNTSMRESVAAHIHDGKICVAECGGMLYLQQSLQHD-EQGVFNEQ----------------------------------------------------------------------------------- +----------------------------------VDLLRALGAELSFFSP----------------------------------------IRHEALPVCDALWLPGGYPEVEALGAHPTLAAALAGHVAAGKPLLAECGGMLALLDSLTDAAGDGVMPGR----------------------------------------------------------------------------------- +----------------------------------LDLLETMGATLLYFSP----------------------------------------LTDSELPEADSLYLPGGYPELQQLADNTALQSAIKQHFEASKPILAECGGMLYLTEKLTDKNGQGLLPAL----------------------------------------------------------------------------------- +----------------------------------LDLLQALGAELHYFSP----------------------------------------LADRELPEVDSLYLPGGYPELAELEGNQSMAASIRAHHQAGKPLLAECGGMLYLLDELRDKQGGGLLSGS----------------------------------------------------------------------------------- +----------------------------------LDLLQALGAELLFFSP----------------------------------------LRFARLPAVDSLYLPGGYPELRALSRNGPMAEAIRAHHAAGKPILAECGGMLYLLDGLTDRGDEGLLPGE----------------------------------------------------------------------------------- +----------------------------------LDLLQALGAELLFFSP----------------------------------------LRFARLPAVDSLYLPGGYPELRALSRNGPMAEAIRAHHESGKPILAECGGMLYLLDGLTDRGDEGLLPGE----------------------------------------------------------------------------------- +----------------------------------LDLLRQLGAELVFFSP----------------------------------------LADTALPLVDSLYLPGGYPELRALADNQGMAEAIRAHHAAGKPILAECGGMLYLLDGLTDKAGAGLLPGE----------------------------------------------------------------------------------- +----------------------------------LDLLRSLGAELTFFSP----------------------------------------LTDSQLPEVDSLYLPGGYPELEALSGNQSMLAAIRAHHDAGKPIHAECGGMLYLCNSLADAEGAGLLPAT----------------------------------------------------------------------------------- +----------------------------------LDLLRALGAELAFFSP----------------------------------------LADATLPAVDSLYLPGGYPELAQLAGNPSMLDAIRAHHAAGKPILAECGGMLYLLERLTDRHGAGLLPGQ----------------------------------------------------------------------------------- +----------------------------------LDCLTAMGAELVFFSP----------------------------------------LTDATLPAADSLYLPGGYPELETLSQNSAMRQAIGEHIKANKPVLAECGGMLYLCRSLTDKNGHGVLDAT----------------------------------------------------------------------------------- +----------------------------------LDLLERFGAELAFFSP----------------------------------------LADSVLPVVDSLYLPGGYPELQRLSGNAPLREAIRAHHEAGKPILAECGGMLYLLDALTDLDGRGLLPGE----------------------------------------------------------------------------------- +----------------------------------LSLLRAMGAELREFSP----------------------------------------LANETVE-ADAVYLPGGYPELSTLAANTATRAALHAHVRAGRPLYAECGGLLYLLEKLADRDGRGLLPGQ----------------------------------------------------------------------------------- +----------------------------------LDLLQAMGAELKFFSP----------------------------------------LHDRTLPPADSLYLPGGYPEHQALAANTSMLSAIRAHHHAGKPLLAECGGMLYLLEALTDVAGEGLLEGE----------------------------------------------------------------------------------- +----------------------------------IDCLQEMGATVKFFSP----------------------------------------LHDKTLPEADAYWLPGGYPELKEISENAGMRDALLAAFNADKPILAECGGMMALSESIN-----GLLAGK----------------------------------------------------------------------------------- +----------------------------------LDCLTDMGANLVFFSL----------------------------------------LHDSALPEADAYWLPGGYPELQDISSNLAMKDSLTSAFKANKPILAECGSMMALSASIN-----DLLPGV----------------------------------------------------------------------------------- +----------------------------------LDCLHALGAQTMFFSP----------------------------------------LHDEALPMIDAIWLPGGYPELSALGRNHAMRTALRQAWQQGLPILAECGGMMALAESIN-----GLLPGS----------------------------------------------------------------------------------- +----------------------------------LDLLRALGASITFFSP----------------------------------------LTDVQLPVADAYWLPGGYPELEKIENNTGMRDSMQAAAAAGIPMLAECGGMLSLGESLD-----GLLKGQ----------------------------------------------------------------------------------- +----------------------------------LDLLQTLGATIQFFSP----------------------------------------LQDAQFPEADAYWLPGGYPELDQLQHNTAMREGLQAAAQSKKPILAECGGMLALSDTLN-----GLLPGT----------------------------------------------------------------------------------- +----------------------------------LDCLREMGAQLEFFSP----------------------------------------LHDQALPAADALWFPGGYPEAATLSANAAMREALQLAWQAGIPMLAECGGMMALSEAID-----GLLPGS----------------------------------------------------------------------------------- +----------------------------------LDLLKKLGAEFVFFSP----------------------------------------LSDAVLPEVDSLYLPGGYPEHRQLAANRQMMDAVQAHHEADKPIYAECGGMLYLCQSLTDKTGEGLLPGT----------------------------------------------------------------------------------- +----------------------------------LQLLQAMGAELVYFSP----------------------------------------LNDSKLPEVDSLYLPGGYPEAAQLSGNKAMQAEIAEHHLMGKPMVAECGGMLYLLDSLTDLQGEGLLSGD----------------------------------------------------------------------------------- +----------------------------------LDCLEALGADLIFFSP----------------------------------------LTDKQLPDIDSLYLPGGYPELETLSQNTNMIQSIHQHYHANKPIIAECGGMLYLCESLTDKADNGILPAK----------------------------------------------------------------------------------- +----------------------------------LDLLRALGAELLFFSP----------------------------------------LADESVPAADALYLPGGYPEATVLATNNCSATSIRAFVASGKPVLAECGGMLYLLEELQDLQGRGLLPGK----------------------------------------------------------------------------------- +----------------------------------LELLAAAGAQLQFFSP----------------------------------------IAGDALPDCDAVWLPGGYPELQALSQRRDLAVALRAHCAQDKPLLAECGGMLFLLEALTGKDGIGLLPGT----------------------------------------------------------------------------------- +----------------------------------VDLLRALGAELVFFSP----------------------------------------LRHEALPACDAVWLPGGYPEAEKLGAHPTLATELAAHIASAKPLLAECGGMLALLDTLTDATGEGLLPGR----------------------------------------------------------------------------------- +----------------------------------LDVLREAGAELRFFSP----------------------------------------LAGDGLPDCDAVWLPGGYPELPALSRNEQLKRELHAHVEAGRPLLAECGGMLYALDSLSNTEGEGLLPGR----------------------------------------------------------------------------------- +----------------------------------LDLLRAMGAEIRHFSV----------------------------------------LQDQQLPEVDSLYLPGGYPEIQQLSGNTVMQSAIRAHHAAGKPILAECGGMLYLLERLADKTGEGLLEGE----------------------------------------------------------------------------------- +----------------------------------LDLLQAMGAELTFFSP----------------------------------------LNDQTLPEADCVYLPGGYPELNSLSKNTSMMNAIKQHYDANKPILAECGGMLYLTESITDKQGEGLIAGK----------------------------------------------------------------------------------- +----------------------------------LDLLRALGAELQFFSV----------------------------------------LADTTLPAVDSLYLPGGYPELQTLSNNLGMRAAIRAHHAAGKPILAECGGMLYLLDELTDKAGEGLLPGS----------------------------------------------------------------------------------- +----------------------------------VQLLEALGARLTYFSP----------------------------------------LADETVPAASALYLPGGYPEASVLAANARAAASIRAHADASRAIVAECGGMLYLLDSVTDTQGVGLLPGS----------------------------------------------------------------------------------- +----------------------------------VDTLEALGARIMWFSP----------------------------------------LADEPVPEADAVYLPGGYPEGEALAQAGRWRDSIRAAHAAGLPILAECGGMMVLAESLADKEGRGLLPGR----------------------------------------------------------------------------------- +----------------------------------VDTLEALGARVSWFSP----------------------------------------LADEPVPEADAVYLPGGYPECETLAQAARWRDSIRAAHAAGLPILGECGGMMVLADVLVDNDGRSLFPGR----------------------------------------------------------------------------------- +----------------------------------LDLLEKMGARLRYFSP----------------------------------------LADEAVPAADAVFLPGGYPECAELVRAANWQSSIRATHARGVPILAECGGMMVLADGLTGQDGQGLLPGE----------------------------------------------------------------------------------- +----------------------------------LDVLRRLGARLCFFSP----------------------------------------LADEAVPAADVVWLPGGYPETEALSRAAHWRGSIRAAHAAGLPILAECGGMMAVAESITDIEGRALLPGR----------------------------------------------------------------------------------- +----------------------------------LALLDALGAQLRFFSP----------------------------------------LADEPVPGCDALFLPGGYPEAAALAANATSAGAIRAHAAAGKPIVAECGGMVYLCDALTDVDGAGLLPGR----------------------------------------------------------------------------------- +----------------------------------LALLDALGAELRCFSP----------------------------------------LADEPVPDCDALFLPGGYPEAAALAANARCAQAIRAHAAAGKTIVAECGGMVYLCDALTDTDGAGLMPGA----------------------------------------------------------------------------------- +----------------------------------IDLLVAMGARVRTFSP----------------------------------------LADEPAPPADALYLPGGYPEAATLAANARTRASIAHHVARGKAVVAECGGMLYLLDTLTDVEGTGVLPGD----------------------------------------------------------------------------------- +----------------------------------IDLLIAMGASVTTFSP----------------------------------------LADEPPPATDALYLPGGYPEVATLASNACTRASIKEHVARERVVVAECGGMLYLLDTLTDIEGNGVLPGN----------------------------------------------------------------------------------- +----------------------------------VDLLQALGASVSTFSP----------------------------------------LANEPIPAADALYLPGGYPEAAALANNACTRESIALHVRRGRTIVAECGGMLYLLDSLTDLEGMGLLPGD----------------------------------------------------------------------------------- +----------------------------------IDLLNALGATVSTFFP----------------------------------------LADEPMPHADALYLPGGYPEAAALASNARTRASIAAHVAAKRTVVAECGGMLYLLDTLTDINGTGLLPGN----------------------------------------------------------------------------------- +----------------------------------VDWLIASGAEVSTFSP----------------------------------------LADEPAPDADALYLPGGYPEARTLAVNAQTRASIERHVSRGRPIVAECGGMLYLLDSLTDIDGTGLLPGD----------------------------------------------------------------------------------- +----------------------------------IDLLEALGATISTFSP----------------------------------------LADEPAAHADVLYLPGGYPEAGTLANGARTNASIRAHVARGGAVVAECGGMLYLLDSLTTTDGTGLLPGD----------------------------------------------------------------------------------- +----------------------------------VDLLEALGASVSTFSP----------------------------------------LANEPVPTADALYLPGGYPEAAAFANNACTRESIALHVRRGRVIVAECGGMLYLLDSLTDLEGMGLLPGD----------------------------------------------------------------------------------- +----------------------------------IDLLASLGARISKFSP----------------------------------------LANEAIPDADALYLPGGYAEAARLASNARTRDSIKQHSDNTKPVVAECGGMLYLLDTFTDIEGKGALKGH----------------------------------------------------------------------------------- +----------------------------------LDLLTALGATLSSFSP----------------------------------------LADEPVPAADALYLPGGYPEAARLATNAASAASIHAHVEAGKPVVAECGGMLYLLDSLTDIDGSALLSGH----------------------------------------------------------------------------------- +----------------------------------LECLENLGARLVHFSP----------------------------------------LADATLPPCDALWLPGGYPEGAAIAANRAMAAALQAHAAAGKPLLAECGGMMSLFETLVSVTGEGLLPGE----------------------------------------------------------------------------------- +----------------------------------LECLAALGATLHFFSP----------------------------------------LADAAPPPCDAIWLPGGYPEGPTLAANRAMAQALATQVAVGKPLLAECGGMMACFDTLYTVEGVGLLPGA----------------------------------------------------------------------------------- +----------------------------------LETLHALGARTAFFSP----------------------------------------LADAALPPCDAVWLPGGYPEAAAIAANRPMAAALAAHVQAGKALLAECGGMIACAETLVDAAGRGLLPGQ----------------------------------------------------------------------------------- +----------------------------------LALLDALGAHVRYFSP----------------------------------------LADEPVPDCDALFLPGGYPEARTLAANRTSAATIRAHAAAGRPIVAECGGMLYLCESLTDVDGTGLLPGH----------------------------------------------------------------------------------- +----------------------------------LALLRDMGAELLFFSP----------------------------------------IHDERLPEVDSLYLPGGYPEHLELSRNTPMLEAIRAHHGAGKPLLAECGGMLYLLDALTDVEGQGLLAGE----------------------------------------------------------------------------------- +----------------------------------LRDWDQSGATILPFSP----------------------------------------LADEPVPEADRLFLPGGYPEAATLASNATFIQSLKYAAQE-TDIYGECGGYMMLGETLIDAEGTGLLGLT----------------------------------------------------------------------------------- +----------------------------------LADWARSGVTILSFSP----------------------------------------LADDPVPDADRVFLPGGYPEARQIASAKTFMQSLKNAAQT-TDIYGECGGYMTLGETLIDGDGTGLLGLT----------------------------------------------------------------------------------- +----------------------------------LVDWAQSGATILPFSP----------------------------------------LADDPVPDADYVFLPGGYPEARQLAGAETFMQSLRSAAQT-SDIYGECGGYMTLGEALIDADGTGLLGLT----------------------------------------------------------------------------------- +----------------------------------LDLLEQMGATLTFFSP----------------------------------------LTDKALPDVDSLYLPGGYPELQALAANRPMIDAIKAHQQAGKPLLAECGGMLYLLESLSDVAGEGLLPGS----------------------------------------------------------------------------------- +----------------------------------LDCLEQLGAQLVFFSP----------------------------------------LTDTTLPEIDSLYLPGGYPELDALSTNTPLKHSITTHYHADKPILAECGGMLYLCESLTDKAGTGLLPAK----------------------------------------------------------------------------------- +----------------------------------LQNLQSMGVEIKKFSP----------------------------------------IKDESIPLADAIYIGGGFPELDQLQKNFDLRNQIKKASKEGLPIFAECGGLMYLTNSIE-YNENGIFNLE----------------------------------------------------------------------------------- +----------------------------------LEALRREGAKLKFFSP----------------------------------------VGDKKIPKCNLIYIGGGFPEGQSLERNTTMRNLIKKYAEEGMPIYAECGGLMYLTKSIS-FGKKGLFDAE----------------------------------------------------------------------------------- +--TLTVGILAS------------TADPAQQATALQQRLSQSGVVATVVGESLA-------------------------------QGVAATYSQSDASGFDGIVVAEGAEGLFQPFLLGRPSQMLIDGYRWGKPVGAVGTASAALAMA-------GI--------------------------------------------------------------------------------------- +--GRVIGIVTG------------PATDMSGVQQLREAVLDAGLVPLIIAPAGGVLGT-----------------------GGDSIPVQRTFATARSVEFDALVFAGVPGSGADAYGDPRVLTLLTEAYRHGKALAGWGGAETLFEAA-------GI--------------------------------------------------------------------------------------- +--TRTVAILAE------------QGFDDEDLSRVLKEFKKADIIPDIVSSALGVIKGT----------------------GGTEIEVGNTLQTVDSVLYDAVYIPGGQESIERLQLHKAASDFINEAFGHYKAIGAAGKGIDLLLSA-------AG--------------------------------------------------------------------------------------- +--ARKVALIAT------------PGADTRLIERVRRALTDARAVPVLVAPTLAPVG-------------------------GLE--PHATLVGMPSVMFDAVFICGGDGDGRDLVHSSDARHFVQEAFKHLKAIAAIGSGRQLLGAA-------HL--------------------------------------------------------------------------------------- +--SRKVAILVA------------DGVDSKAVEAMKAALTAEGAHAKVLGPTSAPVKTA----------------------DGKSLPVDASAEGLPSVAFDAVFVPGGKASIKALEGDGVALHFILEAYKHLKAISFAGEAEELLKTL-------RL--------------------------------------------------------------------------------------- +--SKNVAILLN------------GDPSVSLLSEWIQAFVQHRINYSIIDNKIYQFN--------------------------DSIKVTDTYTTTDSSLFDAVLVFSSESVIQP-----PVLEFAETTFKHFKPIAHVLSNPHALDHS-------K---------------------------------------------------------------------------------------- +--TLQVGILAT------------TKSPSSDAAALKARFGNDGVEVTVIGETLI-------------------------------DGIDQTYSAADATSFDGIVVAAGAEELFKAGSIGRPNQILLDGYRWGKPVGALGSATAALGLV-------GI--------------------------------------------------------------------------------------- +--TLRVGVLIA------------DGFDGNETKYVLSELEEAGLELVFVGERLGDVEGT----------------------DSVKYSIDETFLTGSPLLYDGLYVIGGSDPSRY--FMRKARNFVRDTYNHFKPIGATEEGAVIIEQM-------NI--------------------------------------------------------------------------------------- +--GRKVGILIA------------DGSDADELAAIVTAVEKAKGKAVIVAPKVGGAKLS----------------------NGKQQKADGQLAGSPSQIFDAVAIIVSQEGCATLLNEGAAVEFVMNAFGHLKAIGANETAQPLLDKA-------GV--------------------------------------------------------------------------------------- +--GRVIGIIAD------------AASDVDGVRSARQAVLDTGMVPLVIAPTGGTLGP-----------------------DGDPIAVQRTYATARSVEFDALLLAGEPRAGADAYGDPRVLLLLTEAYRHGKAVGGWDGAERLLESA-------GI--------------------------------------------------------------------------------------- +--GLNVAVLAN------------DTLFSSDMAALQPILNAQNVTLTVVAPRSGELD--------------------------IGVNATASYITTSSIFYDAVFIGSVVATRDATGDDMGAMSFVMEAYSHGKAIVALGGSAGILRSL-------GL--------------------------------------------------------------------------------------- +--GRVVGILLN------------DKTRASDLLAIMTALKAKGVHAKLLYSRMGEVTAD----------------------DGSVLPIAATFAGAPSLTVDAVIVPCGD--IVSLLGNGDANYYLLEAYKHLKPIAFAGDARQFKPLL-------KV--------------------------------------------------------------------------------------- +--GRVVAILLN------------DKVNAADLLTILQALKAKGVHAKLLYSRMGEVTAD----------------------DGSTLTIAATFAGAPSLTVDAVIVPCGN--IADIESCGDARYYLLEAYKHLKPIALAGDARRFKALL-------NI--------------------------------------------------------------------------------------- +--GRKVAVLIH------------NMVKSDALEAIKNWAIKEGVILHLLAPSLAPVKDH----------------------KDNVIVADGMQMSEPSIAYDAVIIPDGDN-LNTVMQDGVARHYLLEAYKHLKPIVFLGNKSDLLEPL-------GL--------------------------------------------------------------------------------------- +--TRKIAVLAA------------NGVDVRGTDRLLRAMRQRGAIPEVLAPVGGGSLTG---------------------GSGGELAVDRAINTMASVLYDAVIVPCGPDSVAALSDDGYAVNFVTEAYKHLKPVGAFGAGIELLRKA-------GV--------------------------------------------------------------------------------------- +--GRKLGILLS------------DGADAAIFKALVKALDAEGAVYEVIAPKIAGVTLA----------------------DGTTVAAKQKIDGGPSVLFDAVAIVVSEQGAALLSIDAAAKDFVTDAFAHCKFIGFTAEAEAIFVKA-------GI--------------------------------------------------------------------------------------- +--SRRIAIIIA------------DGYDPVAFNALYGAIKAQSALPFVIAPRRSAIFSANE-----------------DSSSSKGIVPDHHLEGQRSTMFDAIFVPGGERSIQTLSKNGRALHYIREAFGHLKAIGGTGEAVDLINKA-------I---------------------------------------------------------------------------------------- +--SRRIAILVA------------DGFNFAEVEGLRAALKLGQATTWIIGPRRGKVYPAGQ-----------------VVGTGEGIWADHHHEGQRSTLFDSIIIPSGAEHAQRLAQNGRAIHWVREAFGHCKPIGALGEGVAFLREA-------V---------------------------------------------------------------------------------------- +--GRVVGILIA------------DGSDGAAIAAIKKAAIAAGANVKIVGPKVGLVKLV----------------------GGTLLEVDKQLAGAPSVIFDAIALILSDSGAKKLAAESAAIDFVRDAFGHLKAIGIDRGGAMLLKAA-------NV--------------------------------------------------------------------------------------- +--GRTVAILFA------------EGSDKDAIDELTSSIEGKGGSVYLVAPKVGPLKV-----------------------KGGMLQADGQLAGSPSPLFDAVAMVLMPDQVEKLMKDSAARGWVSDAYSHLKAIGYCPGSKALLEDC-------GI--------------------------------------------------------------------------------------- +--SRRVAILIG------------DGYDPVAFISAKTAIKAAGALPFVVGTKRQPIFAAHQ-----------------HKETDKGVVPDHQYDGARSTLFDATFVPGGEH-IRILSKIGQIRYWIAESFGHLKAIGATGDAVNLVAQV-------LG--------------------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------EALFLPGGESTIARLLHDADLWAPLAHRLAEGLPVLGTCAGLILLSRELAPSPDPPTFGALDVRVRRNDY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALVLPGGESSQDRLLRLLDLASPLRAAISAGLPTLGTCAGLILLAREVLDPAGQRSLGFLDVAVRRNAF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DGLIIPGGESTISRLMLDYDLVSEIKNLAKNGLPILGTCAGMILLAKEILDS-DVEPLGLMDITVKRNAF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------SGLILPGGESTMGKLLRDQQMLLPLREAILNGLPVFGTCAGLILLAKQITSQ-KETHLATMDIVVERNAY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DGIVLPGGESTQGKLLNDLSLLEPLREKIIQGLPVLATCAGLILLSEQVENQ-SKTYLATLPVTVRRNAY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DGIILPGGESTQGKLLRDLKLLKPLQDKIAAGLPIFATCAGLILLAEKIENQ-QENYLATLPVTVRRNAY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DSLIIPGGESTMAKLANYHNLFPALREFVGGGKPVWGTCAGLIFLANKAVGQKGQELVGGLDCTVHRNFF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------SSLIIPGGESTMARLAEYHNLFPALREFVKMGKPVWGTCAGLIFLANKAVGQKGQELVGGLDCTVHRNFF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------SSLIIPGGESTMAKLAEYHNLFPALREFVQMGKPVWGTCAGLIFLANKAIGQKGQYLVGGLDCTVHRNFF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------SSLIIPGGESTMAKLAELHNLFPALREFVQMGKPVWGTCAGLIFLANRATGQKGQKLIGGLDCTVHRNFF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALVIPGGESTMGLVAERSGLLEELRAMTRRQKPVFATCAGLIMLAQRAQHEKGQPLLGGLDVVVDRNFF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALIIPGGESTMAIVARRLGLMDSLRDFVKQHKPVWGTCAGLVLLSEQASATKGQELLGGLDVRVQRNRY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALILPGGESTMALVAERSGIMEPLREWVKAGKPVWGTCAGMILLSNTAHRTKGQTLIGGLDVTVKRNAF-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALIIPGGESTVGTILAHDSLRELLVSRIQQGFPVWGTCMGAILLARSIRND-HRRHLSVMDIEVHRNAY-------------------------------------------------------------------------- +---------------------------------------------------------------------------------------------------DALIIPGGESTISTIALSMDLMDSIRAFISSKKPVWGTCAGLIMLSEFIDGNSEIKTFGGLSVIVQRNYF-------------------------------------------------------------------------- +--TPKVLLPLA------------NGIEEMEAIILVDALRRAKADVVVASIEDGV--------------------------------------EITARYGTRIVADGGMPGAKTLGGCEQLVALLKKQAEANRPYGAIGAATAHVLEPR------GLLK------------------------------------------------------------------------------------- +--MKQVVFVMLDE------------YADWEGAYLSSMLQSDGWEVKTASVRKKVVP-----IGGF------------------HTVTDLTLDQI-SSDIDLLILIGGNS--WN-IENTELKQLIGQRLDNNQSVGAICGA------------------------------------------------------------------------------------------------------- +------------------------------------------VDVTMAGLDGDPVLCSRNV----------------------TLVPNKSLADAEKPQYDAVILPGGLEGSNRLSKSSVVGTLLKEHEKAGKI-------------------------------------------------------------------------------------------------------------- +-MKPKIYLYGTSGQ---------YGNYL-------AALTEAGAKPVLS------------------------------------------RDLFRACGCDGLLLPGGGDIGVTLEATDS--FLIRSFADSGRPILGICRGMQAL--------------------------------------------------------------------------------------------------- +-MKPAVFLYGVPGQ---------YGNYA-------AALEAAGARVVLC------------------------------------------RDLYRSLDCDGLLLPGGGDIRGPLPGTET--FLVDSFVRSRRPILGICRGMQAL--------------------------------------------------------------------------------------------------- +---MKVALAGT-ES---------LTNYI-------AALKANDIEVINT------------------------------------------LDIDKALKCDGLLLPGGGDIDPKYYGEDMAWDVLDAFVKAKKPVLGICRGMQLI--------------------------------------------------------------------------------------------------- +--MKKVALAGT-ES---------LTNYI-------EALRENDIEVITT------------------------------------------LNIDEAMACDGLLLPGGGDIDPAYYGEEMNRDILDAFVKAKKPILGICRGMQLI--------------------------------------------------------------------------------------------------- +--MKKVALAGT-EN---------LTNYI-------DALKENDIEVIAT------------------------------------------LDVDEAIKCDGLLLPGGGDIDPVYYGEEMNRDILDAFVKAKKPILGICRGMQLI--------------------------------------------------------------------------------------------------- +-MKKKILV-FSSNP---------PATYI-------RALRLVNARFTCA------------------------------------------FAPDDLSAYGGLLLIGGGDLHPAFYGGCTPLKAVDYFVGQNLPILGVCRGAQVL--------------------------------------------------------------------------------------------------- +---MKVLIAN--LD---------TPNYI-------KAMSHFGAECVNT------------------------------------------REIPSIEEYDALILPGGDDIDPVFFHQEMNLTLCRRFAEEGKPILGICKGAQVI--------------------------------------------------------------------------------------------------- +-HIPKVQISGQAGG---------LERYV-------RAVERVGAIPVPG------------------------------------------ICPIPDPSCDALVLCGGGDMDPVLFGQENRLALVEAFLTWERPVLGICRGMQVL--------------------------------------------------------------------------------------------------- +-ALKKILIAGEAGQ---------TTNYE-------NALAAMQVHFVTS------------------------------------------LQVKDVDEYDGLLLPGGGDVDPKLFGQLLILAILKAFCQYRKPVFGICKGMQLI--------------------------------------------------------------------------------------------------- +--MKRVLIAGEKDK---------TINYE-------NAMRELGVFVCTS------------------------------------------LHVPDISCFDGLILPGGGDIDPKLFGQLNKLAILQAFILDKKPVLGICKGMQLI--------------------------------------------------------------------------------------------------- +---MNVIITQ-LNK---------HGDWI-------DSLENSYIIYFET------------------------------------------FGVNRSVEIAGIILTGGGDVDPDLYGKNAGSSLLKLSISQKIPLLGICRGMQFI--------------------------------------------------------------------------------------------------- +-MVKKIGITLRIQE---------YDEKR-------DALSHDWFDFFQK------------------------------------------LNCLEEMDLNGLILSGGDNIGDD------PKKIMTFAMTNNIPLLGVCRGMQVI--------------------------------------------------------------------------------------------------- +---------MRILQ---------TRENH-------DMISHDWLNFLHS------------------------------------------LQFELKDNIQALILSNGNDIGMFNN-RDKSLQLLQHAIKNKLPVLGVCRGMQFI--------------------------------------------------------------------------------------------------- +-FMKKIVIAGNSGS---------TENYA-------EALTRLGASCTVT------------------------------------------TDCRFAGDFDALLLPGGGDIDPVLFGESDHLAMLDAFVRLSRPVLGICKGMQII--------------------------------------------------------------------------------------------------- +-MEKRVLIWDDGLN---------YVNYM-------EALRAVDLTPVVG------------------------------------------REAA--GPCAALLLPGGGDIADRLPEDEI--RTIRAYAAAEKPILGICRGMQAL--------------------------------------------------------------------------------------------------- +--MKEILIAGVPDK---------IGNYR-------RAVEALGAVSRGL------------------------------------------YTCSEAEGCDALLLPGGGDIAPELFGQKDQLRILDSYIRRKKPVLGICKGMQII--------------------------------------------------------------------------------------------------- +--MKKIAIAGISGN---------TENYR-------NALSQLGAVCTTL------------------------------------------TDASRASQFDALLLPGGGDIDPVLFGETDHLSMLDAFVSAGKPILGICKGMQVI--------------------------------------------------------------------------------------------------- +--MKTVLIAGENGK---------TENYE-------KALRSLGILPVCS------------------------------------------LKAPYVYRYDGLLLPGGGDIDPRLFGQLSMLAILNGFVQERKPVLGICKGMQLI--------------------------------------------------------------------------------------------------- +--MPKIYVYGSRDK---------LENYA-------NALEGSGLEGLFS------------------------------------------LDISQAEECDGLLLPGGGDIDPARYGQLPALELVSRFLAWGKPMLGICRGVQLL--------------------------------------------------------------------------------------------------- +--MLRIAVTNRPQA---------VVNYL-------DALARTEGRGETG------------------------------------------RSF-SPDEYDGLLLPGGWDVNPSRYGRERIFEALARFLEAGKPVLGICRGHQLL--------------------------------------------------------------------------------------------------- +--GIQAAIVGRSKD---------TLNYE-------KALDAMGVHYLTT------------------------------------------MDPGKLSDMDALLLPGGGDITPAFFGQKNHLQALDIFYKARKPVLGICKGMQVI--------------------------------------------------------------------------------------------------- +-TGLRVLVVQPGND-------APGGSFC-------KELACCGAALTTLRTGREDA---------------------------------LPPRDEALAGYDAMVVLGGHQHCRDSPHFPHLMDLLRAFDAAGRPVAGICLGAQLLARA------------------------------------------------------------------------------------------------ +--SARILVVRERDL-------SPEGTFC-------KELERQGAMLVTLRPDGGDP---------------------------------LPET---LSDFDGLVVFGGPEQIQNKGYLDPLMRLMRECDAAGKPVAGIRHGCHLLALA------------------------------------------------------------------------------------------------ +-IGSRVLVIQHSDE-------SPGGNFT-------KELARQGCLLTTVMPGEGDA---------------------------------LPDSP---EGFDRLVVLGGPQHAFDSPHFPALMQLMRGFDAAGKPVAGICLGCQILARA------------------------------------------------------------------------------------------------ +-MGARILVVRHSPH-------APGGVFC-------KELERLGAILTTVSPLEGDA---------------------------------LPQTP---DGHEGLVVLGGPQHAFDSPHFVPLMRLMREFDAAGRPVAGICLGCQLLARA------------------------------------------------------------------------------------------------ +-RPPQVLVIQHGLH-------SLGGNFL-------KHLEQQGCRLHTVRAFEGEA---------------------------------LPHTP---QDYAALVVMGGPQHAWDWPHIPPLLRLMREFDALGRPVAGVCLGAQLLARA------------------------------------------------------------------------------------------------ +-TGLRVLVVQPGCD-------APGGNFC-------KELERCGAALATLRPGHGDD---------------------------------LPSLDEALAGYDALVVLGGPQHCSDSPYFPHLMDLLRAFDAAGRPVAGICLGAQLLARA------------------------------------------------------------------------------------------------ +----------------------------------------------------------------------------------------------DLEAADGLVIPGGESTMGLIAERTGILSSLREFVSRKKPVFGTCAGLIMLADSAKKEGGQPLLGGLNVLVDRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELNACDGIIIPGGESTMKIISDGGDIIEGLRHFALSGRPVWGTCAGTILLAKTVQECKYGNPIGVMDIKVSRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------NLRECDGIVIPGGESTLRKCMSYDSLYNALKNYIHKKKPVWGTCAGCILLSEKVKEYGNDFSLGGLDIEITRNYY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLGLCDGLVIPGGESTVRRCCAYETLYNALVHFIHLKKPIWGTCAGCILLSKNVNNFGNKFSFGGLDITICRNFY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELRRCDALIIPGGESTISFVATQSGLMEPLREFVKKRKPVWGTCAGAILLADEANKKGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DIKNLDALILPGGESTFYKLVLNAGIFQELKK----IKNIFGTCAGAIFIAKNINKIKGQKSLEVMDMEVDRNAY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------SLQNLDALIIPGGESTLHKLCEREGMWEKMKK----IKNIFGTCAGAIMLAKVIHKTLGQKTLELMDIEIDRNAY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEKCHALIIPGGESTISLVAQRSGLLEPLRAFCNPNKAVWGTCAGMILLSKEATMRGGQELFGGMDITVNRNQY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELRSCCGLIIPGGESTMSLVASRSGLLGALREFCSPNTAVWGTCAGMILLAKEASKKGGQELFGGMDMIVNRNQY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELASCDALVIPGGESTFGIVAERNGLLDDLRRFVRGSKSVWGTCAGLIVLADQISKSDGQPLIGGLGVRVCRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEGLDGLVIPGGESTMAKFLLRNNFIGALRHYIRPAPAVWGTCAGLILLSDHVLKEGGQCNIGGLPITSTRNTY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELEQCTALIIPGGESTMALVAHRSGLLEPLRAFVK-TRPVWGTCAGAILLSEEVVKQGGQELIGGIEVKTARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLLTVSSLIIPGGESTMAKLAEYHNLFPALREFVKTGKPVWGTCAGLIFLADRAVKEGGQELVGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDGLIIPGGESTISFVAAQSGLLEPLRDYVKQKRPVWGTCAGLILLSNEANKKNGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELELCDSLVIPGGESTIQKLAVAYGLFEPIRKKIQAGFPVFGTCAGLIMLADEID-VSGQAGFGGLHVSVRRNAF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLDKLDGLIIPGGESTMTILLQRTQMFDRLQYMIQEKLPVWGTCAGLILLSNHVSGDLSFKPLGGLDVQVERNSF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDGLIIPGGESTISFVAAQSRLLEPLRHYVKQKKPVWGTCAGLILLSDEANKKGGQELVGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLETIDALIIPGGESTMALIAERSGLMEPLRKFVRDEKPTWGTCAGMILLANEANKKGGQDLIGGLNITVNRNQF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDGLIIPGGESTISLVAAQSGLLEPLRDYVKQKKPVWGTCAGLILLSDQANKKGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELDQCDALVIPGGESTIALLARLSGLLDPLREFIA-RKPVWGTCAGAILLARSVEKKGGQELLGGMSITIQRNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLAELSGLIIPGGESTMAKLAEKNNLFPALRKFGSSGKPIWGTCAGLIFLAAKAVKEGGQELLGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELGSCAGLIIPGARSTMALVAERWGLIPELRQFAAQQRPIWGTCAGLIFLADRASKEGGQALLGGLDCTVQRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLVGLSGLIIPGGESTMAKLAEKNNLFPALREFSTAGKPIWGTCAGLIFLADRASKEGGQKLLGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DCENIDGLIIPGGESTIGKLINIDEKLRDRLEHLVQGLPIWGTCAGMILLSKKSRKFPDPYLLRAMDIEVTRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DVAGIDGLILPGGESTQGKWLAASDLGETLRDLTGRGVPVFGTCAGFILLADRLRKEGGQYRLGGMAVEIERNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLSSLHGLIIPGGESTIGYLLSIDGLGEEIKARVKKSLSIWGTCAGMILLAKKVEKKGGQYILGCLDIVIKRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DCKNIDGLVLPGGESTMGRLIGIDSDLKENLESLVRGVPMWGTCAGMILLSKKSHKFPDPYLLRAMDIEVTRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLNKCAALIIPGGESTIALLAKLSNLLEPLRQFVK-TKPVWGTCAGAILLSQSVEKKGGQELLGGLSIKISRNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAQCDALIIPGGESTIALLARLAGLSEPLKEFVK-VKPVWGTCAGAILLSQAVEKKGGQELLGGMSITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEKCDALIIPGGESTIALLARLSGLLEPLRLFIK-TKPVWGTCAGAILLSQSVIKKGGQELLGGMSIRIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLNRCDALIIPGGESTIAVLARVSGLLEPLRQFVK-TKPVWGTCAGAILLSQTVEKKGGQEILGGISIAIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLDRCDALIIPGGESTIALLARLSGVLEPLKLFVK-TKPVWGTCAGAILLSQAVEKKGGQELLGAMSITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELAKCAALVIPGGESTIALLARLSGLLEPLRQFVK-TKPVWGTCAGAILLSKNVEKKGGQELLGGISITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDALVIPGGESTISFVAQQSGLLEPLRDFVKQKKPVWGTCAGLILLCDEANKKGGQALIGGLSVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLGQCDALVIPGGESTISLIAERTGLLEPLRKFVKDKKPVWGTCAGMILLSERATSRGGQQLIGGLDVTVIRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------VLARCDALIIPGGESTIALLAKLAGLLEPLRQFSK-SKPIWGTCAGAILLAQVVEKRGGQEVLGGVSVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCAALIIPGGESTIALLAKLAGLLEPLRAFLK-EKSVWGTCAGAILLAQSVEKKGGQELLGGISVTIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEKCDALIIPGGESTIALLAKLAGLLEPLRQFSK-TKPIWGTCAGAILLAQVVEKKGGQDLLGGMSVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAKCDALIIPGGESTMAILARSLGLLEPLKEFIR-TKVVWGTCAGAILLSQSVEKKGGQELLGGISVKIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEKCDALIIPGGESTIALLAKLSGLLEPLREFVR-KKSVWGTCAGAILLAQAVAKKGGQELLGGVSVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLQRCDALIIPGGESTIALLARLSGVLDPLKEFVK-TKPVWGTCAGAILLSQAVEKKGGQELLGAMSITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAQCSALIIPGGESTIASVAARTGMLDLLKEFCQVDKPVWGTCAGCILLAKEATKKGGQELFGGMGVGVKRNGY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLAQCNALIIPGGESTISFVAAQSGLLEPLRDFVKQKRPTWGTCAGLILLSDEANKKGGQELIGGLSVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DPAQIDALIIPGGESTMALVAERSGCLDALREFVH-KQPTWGTCAGMILLSTTATKQGGQNLLGALDITVQRNAF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELDQCNALIIPGGESTISFVAAQSGLLEPLRDFVKQKRPVWGTCAGLILLSDEANKKGGQELIGGLAVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLRRCDALIIPGGESTISLVAAQSGLLEPLRDFVKQKKPVWGTCAGLILLSEQANKQGGQDLIGGLAVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLDSCDALIIPGGESTISFVAAQSGLLEPLRDFVKQKKPVWGTCAGLILLSNEANKKGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDALIIPGGESTISFVAQQSGLLEPLRDFVKQKKPVWGTCAGLILLSNQANKKGGQELIGGLNVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELSSCDALIIPGGESTISLVAAECGLLEPLRSFVKDRKPTWGTCAGLILLSEQANKKGGQELIGGLAVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDGLIIPGGESTISFVAAQSGLLEPLRDFVKQKKPTWGTCAGLILLSEQANKKGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDALVIPGGESTISFVAAQSGLLEPLRQFVKEKKPVWGTCAGLILLSEHVNKKGGQEVIGGIDVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCDGLIIPGGESTMALLARKAGLIDPLCDFVR-KKPVWGTCAGAILMSRAVIKKGGQEVLGGMSLTIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELELCDGLIIPGGESTIILLARLANLLEPLREFVR-TKPVWGTCAGAILLASGVEKRGGQEVFGGVDIRIGRNGF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELAECDALIIPGGESTMALLARISGLLEPLREFVQ-RKPVWGTCAGAILLAESIEKKGGQELLGGMAVKIGRNGF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELDTCDALIIPGGESTMAILARNTGLLEPLRQFVR-TKPVWGTCAGAILLAESIEKKGGQELLGGMSVKIGRNGF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLRRCDALIIPGGESTISLVATQSGLMEPLREFVKNRKPVWGTCAGAILLADEANKKGGQELIGGLAVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCTALLIPGGESTIAHLAAESALLDPLRAFVAAGRPVWGTCAGAILLADEAVKKGGQALIGGLAVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELSTCEALIIPGGESTLSLVAQQSGLLEPLRDFVKKRKPTWGTCAGLIFLSEEATKRGGQELVGGLDVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLDRCDALVIPGGESTLAFVAKQTNLMEPLKRFVKDSKPTWGTCAGLILLADEATKKGGQELVGGLHVRAHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLARCDGLVIPGGESTLAFVARQTNLMEPLRDFVKDRKSTWGTCAGLILLADEATKKGGQELVGGLHVRAHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------HLRDVRGLIIPGGESTMANIARRFGLFEPLRAFQASGRCVWGTCAGLIFLAERLRKEGGQELLGGLDVGVNRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLLNVASLIIPGGESTMAKLAELHNLFPALREFVRMGKPVWGTCAGLIFLANKATKTGGQGLVGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLLNVSSLIIPGGESTMAKLAELHNLFPALREFVQMGKPVWGTCAGLIFLANKATKTGGQKLIGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLNTISSLIIPGGESTMAKLAEYHNLFPALREFVQMGKPVWGTCAGLIFLANKAIKTGGQYLVGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLNSVDCLIIPGGESTMALIAERCNMLEPLRAFVQ-KKPTWGTCAGMIMLAKEATKRGGQQLFNALDVVVQRNQF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLKQIDALIIPGGESTMALIAERCNMLEPLRAFVQ-QKPTWGTCAGMIILAKEAHKKGGQQLLNALDVSVNRNQF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLNQVDALIIPGGESTMALIAERCNMLEPLRAFVQ-KKPTWGTCAGMIMLAKEAHKKGGQQLFNALDVSVNRNQF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLNSVDCLIIPGGESTMALIAERCNMLEPLRAFVQ-KKPTWGTCAGMIMLAKEATKKGGQQLFNGLDVVVNRNQF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLSLCDALIIPGGESTMAIVARRLGLLEPLREFVKNNKPVWGTCAGLVMLAEEASKQGGQELIGGLDVRVLRNKF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------QLAACDALIIPGGESTISLIAERCNLLEPLRDFVKQRKPTWGTCAGLILLAESANKAGGQELIGGLDVRVNRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAPCRGLIIPGGESTISLLIRKSGLYEPLKEFVRRGKSIWGTCAGMILLAREIDVSEGWDGLDGMDVRVGRNSY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEQCRALIIPGGESTISLLIRKSGLYEPLKEFIAKGRSVWGTCAGMILLAREIDTSEGWEGFDAMDVKVARNQY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEQCRALIIPGGESTISLLIRKSGLYEPLKEFVAKGRSVWGTCAGMILLAREIDTSEGWEGFDAMDVKVARNQY-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------HLEKIGSLIIPGGESTMAKLAHYHNLFPALREFVKSGRPVWGTCAGLIFLADRAIKNGGQEFIGGLDCTVHRNFF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------GVAGIDGLVLPGGESTMGIMTEGDGLWETIRAAVDGGLPVYGTCAGLVLLADRAIRDGGQPLIGGLDCDCCRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLSLCDALIIPGGESTIALLARLSGLLELLKEY---EKPIWGTCAGAILLSRQVVKKGGQEVLAKMDVKVGRNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCDALIIPGGESTIALIAAQSGLLEPLRGFVKAKKPTWGTCAGLILLAEAANKKGGQELIGGLDVKVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELAICDALILPGGESTLSLVAAQSGLLEPLREFVKSKKPVWGTCAGLILLCEQASKRGGQELIGGLDVKVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELEKCEGLVIPGGESTISLVAQRSGMLDALRKFVTDKKPTWGTCAGLILISSGIYDQTVSALFGGLDVVVSRNYF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELRSCDALIIPGGESTISFIAAQSGLMEPLKEFVKDRKPVWGTCAGAILLADEANKKGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCEALIIPGGESTIALIAAQSGLLEPLRDFVKSRKPTWGTCAGLILLSEQANKKGGQELIGGIDVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLDKCDALIIPGGESTIALLARLAGLLEPIREFLK-TKPVWGTCAGAILLAQWVEKKGGQELLGGISVTVERNGF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELDRCDALIIPGGESTIALLARLEGLLEPLREFRT-RKPVWGTCAGAILLSQSVEKKGGQEVLGGMSITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLSQCDALIIPGGESTIALLARLAGLLDPLKEFGK-IKPVWGTCAGAILLSESVVKKGGQELLGGMSVKIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELNQCDALIIPGGESTIALLAKLSGLLEPLRQFVK-EKPVWGTCAGAILLAEKVEKKGGQEVLGGMSITIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLEKCDALIIPGGESTIALLARLAGLLEPLRTFLK-KKPVWGTCAGAILLSQAVEKKGGQELLGGFSVTTARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAQCKALIIPGGESTIALLARLAGLLEPLRAFVT-EKPVWGTCAGAILLAESVEKKGGQELLGGVDIKVGRNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLDKCDALVIPGGESTIALLARLAGLLEPLAQFLK-TKPVWGTCAGAILLSSAVEKKGGQEVLGGVSVKIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLPTCDALIIPGGESTIALLAKLAGLLEPLRTFLQ-KKPVWGTCAGAILLAQAVEKKGGQELLGGISVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLSKCDALIIPGGESTIALLARLAGLTEPLREFIA-KKPVWGTCAGAILLSEEAEKKGGQELFGGVTIKTKRNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAKCDALIIPGGESTIALLARLAGLLEPLRQFTK-TKPIWGTCAGAILLAQAVEKKGGQELLGGMSVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLKKCDALVIPGGESTIALLARLAGLLQPLRDFVK-SRPVWGTCAGAILLAQAVEKKGGQELLGGISVTIMRNGF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAKCDALVIPGGESTIALLARLAGLLEPLRDFLK-RKPVWGTCAGAILLAQSVEKKGGQELLGGMSIAIARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLESCDALIIPGGESTIALLARLAGLLGPLRDFVK-TKPVWGTCAGAILLAQSVEKQGGQELLGGMSVTVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLARCDALIIPGGESTIALLARLAGLLGPLRDFVK-TKPVWGTCAGAILLAQAIEKKGGQELLNGISINVARNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLAKCGALIISGGGSTNALLARLAGLTDPLKAFVQ-VKPVWGTCAGAISLAENAVKKGGQELLGGIAVKMERNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLERCSALIIPGGESTIALLLRLSSLLEPLRAFSA-TKPIWGTCAGAILLAKEIAKKGGQEVLGQVSVRIERNGW-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------DLLRCSALVIPGGESTIANLARQSGLMQPLRDFVQQKKPVWGTCAGLILLADEARKIGGQELIGGLAVRVQRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ELARCDALIIPGGESTISFVAAQSGLLEPLREFVKLKKPTWGTCAGLILLSEQANKKGGQALIGGLDVRVHRNHF-------------------------------------------------------------------------- +----------------------------------------------------------------------------------------------ALARCDALIIPGGESTISLVAAQSGLLEPLREFVKLKKPTWGTCAGLILLSEQANKQGGQELIGGLGVRVHRNHF-------------------------------------------------------------------------- +-----------------------DNFTLISLASAIEPLRMANYRWSTLSADGSQVWASDGL----------------------QVTPDASM--YKAPVLDMVIVCGGVG--IQRTVNREHVSWLQSQARQSRRLGAVCTG------------------------------------------------------------------------------------------------------- +-----------------------PGFPMACLTSAIEPLRAANFSWRLIGEEASPVRSSAEV----------------------RFDPDQTLT-EAAGLDYLFFLSAPVS--R-FQNPKRSNAQVRWLDRCGVVLGG----------------------------------------------------------------------------------------------------------- +-----------------------PGFSLLAHASAIEPLQMANYHTVTLSLDDEPVRSGAQL----------------------SLLAQHTLS-APLGPMDLLFICAPTP--LPYALPAKLNEWLRSHQGRGVAFGGLAGG------------------------------------------------------------------------------------------------------- +---------------------------------------------------------------------------------SISLTPNLILCDTQLKEYEVIIVVGGSEA--RLNLDSRLTEQLYEAAKANRLLGGIWNGAYHLAAA-------GLTEGYECII---------------SGDGMFTIEPSLNERKS---------TSYWQFDGRRMTSRDASSAVFMMDA------------- +--TRKVAVIAG------------EGFKGNAVNEILSTFKSEGVTAEIVSQKQGKLKGEDGS----------------------ELAIDHTFQTADPVLFDAIYVAGGEINDKSFK--QSAVYYVSEAFKHFKPIGGTFEGKQLLKEN-------DF--------------------------------------------------------------------------------------- +--TRKVAVLAA------------DGFDADEMKAVLAAFAEAKVVPEVVSENLGMIAGSDGS----------------------RLEVMHTFLTADSVLFDAVYVAGGEQSMAKLQGIKEAVNFVTEAYNHFKTVGASAQAAGLLSGS-------GI--------------------------------------------------------------------------------------- +--SRRVAILIE------------DGFDYNEVMQVKEALEAAGAHPKIISKLLGKRVSSTGQ----------------------EIEVDKHHVSADSIMFDAVYIPDGEKSVRKMMGLGDALHFVAESFKHCKPIATSGFGINLLEKA-------FV--------------------------------------------------------------------------------------- +--SRRIAVLAA------------DGVDVVGTQRFTELMEQRGAVVEVLAPVAGGLAGGSGG----------------------ELRVDRSFTTMASVLYDAVVVACGPRSVSTLSDDGYAVHFVTEAYKHLKPIGAYGAGVDLLRKA-------GI--------------------------------------------------------------------------------------- +--GRAVGILYA------------DGSDGGAIDAVKSAVEKAGGMVKLVAPKLGGAKLADGQ----------------------MRKADGQLAGTPSHVFDAVAIILSKDGAAKLSNEGDAVQFAMDAFGHLKAIGASDGAKALLEKA-------GV--------------------------------------------------------------------------------------- +--SRKVAILVA------------NGVDGKAVEAMKKELTAKGAHAKVLGPTSAPVKTADGA----------------------SLPVDASAEGLPSVAFDAVFVPGGKDSVKALSTDGVALHFILEAYKHLKAISVAGEAKELLTLL-------RL--------------------------------------------------------------------------------------- +--GFKIAVLAS------------VS--SPGAAELATAFAPSKVTVAVIAERLVP-------------------------------GVNATYSAADASTFDGVIVASGAESLFTFFPAGRPAQILGDAYRWGKPVGVLGTASGVLAAV-------G---------------------------------------------------------------------------------------- +--SLNVGILAT------------NFNGSTTAGSIAQALQGKGVNGVVIAETLXA-------------------------------GVNATYIGADAALVDGIIVCDHTANLFPLYPPQRPMLIVQAAFTYGKPIGAIGGGKQALDHA-------LS--------------------------------------------------------------------------------------- +---------------------------------------------------------------------------------NMQLTHDIASAAVAPGKLDILVIPGSDP--KFVPSEAMAAYILAQSTSPQTDVLSICTGIFPLARSP------GVLDGRVATGPRPLVDM------------------KLRKLKADWHD-----HRRWEVDGELWTSGGITEGTEM---------------- +---------------------------------------------------------------------------------GPAVVPTMTYAEADGKEFDIILIPGGPSPNPGLA-DPSLMD-----------------GSWLLAGT-------GLLTGKRATTNKSMYRMIVE---------------DTKEFNVTWV-------------------------------------------- +-HSSDALVIQLDPT-------YGPGQLV-------PALERAGLQMHLVQPHRG-----------------------------------DQVPTD-LRRMEGLVVLGGALHAHDVPHLRAVRALLRTARGRNLPTLGIGLGAQLLALA------------------------------------------------------------------------------------------------ +-HPSDVLVIENEAD-------CPPGLLA-------DVLSRAGLTMHLHRPYRG-----------------------------------DQLPAD-LGTFEGLVVLGGGMGARDHPWLPQTRRLLALAVDRHLPTLGICLGAQLAAIA------------------------------------------------------------------------------------------------ +-DTLTITVIEPEEL-------APVGRLG-------EWLFAEGAALRMVRPWRG-----------------------------------ESIPSLE--VGDGLVVLGGSMSAHDHPWLADLRELLRGVVAEDVPAIAICLGAQVAAEA------------------------------------------------------------------------------------------------ +--MTRITIFQPHPE-------CPPDRLA-------EWLPDVDC--GTVRLWE------------------------------------EPVPQAS--WGDGAVVLGGPMGAHDHPWIGDLAEGLREAVGAGLPVLAICLGHQILAAA------------------------------------------------------------------------------------------------ +-TSPRLLVLQPSKS-------DPLAKLG-------DWLDAEGIELDLVLLK-E-----------------------------------QPAPATL-DGYQGVICLGGEMGALDHPWLADVRKLLSNAVAKRLPTLAICLGAQLLAAA------------------------------------------------------------------------------------------------ +-TGVRILVVQPSEH-------APLGRLG-------EWLSELGAELDVLDPW-R-----------------------------------HELPGTP-EEYSGLVVLGGETNARAHAWLAPTRKLLSGATSTGMPVLAIGLGAQLLATA------------------------------------------------------------------------------------------------ +-TTTRILVIQLADL-------DSPGRLA-------EWLVDSGAEVELVRLD-R-----------------------------------TGELPEP-RDFAAVVCLGGPMNANDHPWLRTLRAFFGTCVTRRVPLLAICLGAQVLATA------------------------------------------------------------------------------------------------ +-RMTRLLVIQPDDS-------DPAAALG-------GWLTEAGAELHVVRPF-E-----------------------------------EAL-PAL-ADYQGVVCLGGEMGALDHPWLKDVRQLLASATGNRVPVLGVCLGGQLLAAA------------------------------------------------------------------------------------------------ +-SATRILVVQPDPS-------DPPGPLG-------DWLTEAGAELELRRMP-A-----------------------------------DGIPDDV-GGYDALICLGGGMGAEDHPWLADVRRLLARAAAQDLPTLGVCLGAQLLAVA------------------------------------------------------------------------------------------------ +-PVTRLLVVVPSDT-------DPPARLG-------QWLADAGLELDARHCDRG-----------------------------------DELPADL-TGHDGLLVLGGPQSSLDSPELVGVRHLLAQALAADVPTLAVCLGAQLLAQV------------------------------------------------------------------------------------------------ +-STSRLLVIQPDAA-------DPPGPLG-------EWFVDAGAELDVRLMP-D-----------------------------------AGLPDTL-DDYGGVVCLGGGMNAEEHPWLAAVRSLLGKAVAADKPTLCVCLGAQLLAVA------------------------------------------------------------------------------------------------ +-QARTVHIIQHLEH-------IPAGYLA-------DYLISEGTQVNLIRAWEL-----------------------------------DGFSN-AVKTTDSLVVLGGSMNAYAYPWLKAVRELLVRRPESAGKTLGICLGHQLAAVA------------------------------------------------------------------------------------------------ +-GAVQILVIELSSL-------DPVGNLG-------EWLTAAGAETTVVRPV-E-----------------------------------RELPDP--TDFQGVIVLGGEMGVYDHPWLSQVRSLLSTALGQKQAVLGIGLGAQLLAVV------------------------------------------------------------------------------------------------ +-SAPRLLVIQPDPF-------APLGPLG-------DWFAEADASVDLRLMP-D-----------------------------------RELPSSL-DGHDGVVVLGGGMNAEQHPWLAGIRTLLSAAVAQDRTTLCVCLGAQLLAVS------------------------------------------------------------------------------------------------ +---MTVLVVEHEPE-------APPGRLG-------A----TSLDLHVVRPYAG-----------------------------------DVVPDDL-SDFAGFVVLGGEMGAYDHPWLAPTRELVRRAAATDVPTLLVCLGHQLGAVA------------------------------------------------------------------------------------------------ +-SLPRVLVIQHEET-------VPPALFG-------HWLAEAGMCVDVCRAYAEP---------------------------------IPPLSSLD-ASYSGLLVMGGSMDADSHPWLQVTRERIAQAAEAGIPTLGICLGHQLAAMA------------------------------------------------------------------------------------------------ +----MIHIIQSDGD-------VPAGLVE-------GELRRLGVEQRTIGLHIS-----------------------------------EALPEIS--AVRALVVLGGAMGANDHPFLTELKRFIAQAMEREIPCLGICLGGQLLSLA------------------------------------------------------------------------------------------------ +----MLLVIQNDPR-------VPPAFFG-------TLLMEWGIAHRVLRLFAG-----------------------------------DPMPDSS--ETSAVIVLGGTMGVHDFPFLEPLSGLIRDAADIGTPLLGICLGGQLLAHA------------------------------------------------------------------------------------------------ +-MNKHWAVVKHVPF-------EGPALVG-------TLLAERGIRYTEYPMYRA-----------------------------------SELPAVH--DIGGLVVMGGPMGARDHPQLPRERNFIKESVDAGLPMLGICLGAQLLAAS------------------------------------------------------------------------------------------------ +----MFLIVQNDPH-------CPAGGLY-------LLLDAAGHPYQTVAAFAS-----------------------------------EPFPDPA--ALTGVVVLGGEMGAHDHPHLCRVLDFIGCALRAGTPLLGICLGGQLLSHA------------------------------------------------------------------------------------------------ +----MITVLQPDVT-------VPLDRFS-------DWIAEEGQDYRVIPLEH------------------------------------QPVPALD--CGAGIIVLGGRKDAVTSPFLEDVYRLLRAAVDREVPVLGICLGHQILGHA------------------------------------------------------------------------------------------------ +-NAPQITVVQPDPR-------APLDRFE-------GWLTDAGATLHLVDPAV------------------------------------DGVP--E--AGDGVIILGGTDNC--YPWLTELHASIRSWLSAEVPVLGICLGHQILADA------------------------------------------------------------------------------------------------ +----MLVMIQNDSE-------VPPGIFG-------DFLREERIPFSLVHPCAG-----------------------------------DPLPLPA--EVTAAIVLGGAMGVHDHPFLETVKAFIGGCVAAGRPYLGICLGGQLLADV------------------------------------------------------------------------------------------------ +----MIVIVQNDPE-------VPCGVLP-------ELAEQKCIGYEIVPAFEG-----------------------------------VEYPEVH--GIRGAVVLGGKMSVHDHPFLDRVKKYIGRLLADAVPFLGICLGGQLLAEV------------------------------------------------------------------------------------------------ +----MLLVVQNDPR-------VPLGTYA-------DYLAEAGVPFRTIHPYAG-----------------------------------ETLPNPA--GIGAVIVLGGAMGVHDHPFIAEVEFFIAHVVAKEIPFLGICLGGQFLAHV------------------------------------------------------------------------------------------------ +----MLIVIQNDPE-------VPLGAYA-------DYLAELDVPYRLFHPYEE-----------------------------------EMLPEAG--EVSAAIVLGGAMGVHDHPFLREVNCFIGGAIAQDLPFLGICLGGQLLASL------------------------------------------------------------------------------------------------ +----MLHIIQNDPD-------VPPGNLA-------ENLETLEIAFRLHHLYRG-----------------------------------EALPSPA--EMTALIVLGGAMGANDYPFLTPLKALIAEVVHAGIPYLGICLGGQLLAAA------------------------------------------------------------------------------------------------ +---MNILIFQHTPG-------ENPGAFL-------EHISSCGDTASIVHFYDG-----------------------------------QPIPQLD--EFDLLLVLGGPMDVWEHPWLVREKQAIRTWVQDLRPYFGICLGHQLLVDA------------------------------------------------------------------------------------------------ +-----MLVIEPDPI-------ATLDRFD-------AWLTEHGVTAHIVRPHAG-----------------------------------DAVPTIA---YAGVIVLGGRMSAHDYPWLLDIFALIRDAADRATPSLGICLGAQLISQA------------------------------------------------------------------------------------------------ +-GNLQALVIQPDFH-------CPLDRLG-------VWLQDEGITTRIIQPFSG-----------------------------------DVIPDVI---EDGLVVLGGDMSSLDYHWLTDIRRLMAVAASQRKPTLGICLGAQLMAQT------------------------------------------------------------------------------------------------ +-AQPAVLVIQHDVD-------DNLGELA-------PPLAEAGIRIVMWDAGVP-----------------------------------DGAPATL--GFSGLISLGAYAGVRDKEWMPVEKALMQQALTRRMPVLGLCFGAQLLAAA------------------------------------------------------------------------------------------------ +-ARRALTVIQHEDD-------CPPGMLE-------PLARAAGLTLNVIRPYRG-----------------------------------EALPSLSASTSRGLIILGGGPGPLEYNWLAPCRKLCLDAVEITFPLFGICLGEELLGAA------------------------------------------------------------------------------------------------ +-PARTVLFLQHIEV-------EKPGLIL-------EALDGSGLHADITPGASA-----------------------------------NDLPPVS--DLAGLVVMGGPMNADDHPALKLERDLLADALRAGIPTLGVCLGAQLLARV------------------------------------------------------------------------------------------------ +-GGNVILFIKHIDI-------EGPGTIA-------DFLEDNKLPYEVIDLSHG-----------------------------------DKVPKLE--NFQAVISLGGPMNVYEYRFLKDEDILLKRIAEEEVPFLGICLGAQLIAKA------------------------------------------------------------------------------------------------ +---MKYMVIQHIES-------EGPGSLG-------AYLQAQGDTLDTIHVYNG-----------------------------------DILPADA--GYKAVISLGGPMNVYEYPFLKAETDFLRNIVDAGTPVLGICLGAQMIAKA------------------------------------------------------------------------------------------------ +---MTVAIIKHIDI-------EGPGTIG-------DFLNDDGISYDVIDVFNG-----------------------------------EPLPNSL--DTSAVIILGGPMNVYEYLFLKQEDEFLKEVIEKGLPALGFCLGAQLIAKA------------------------------------------------------------------------------------------------ +---MKVIIIKHIDI-------EGPGTIA-------DFLDDKNIPYEVIEIFNG-----------------------------------EPLPNSL--NTSAIIILGGPMNVYEYPFLKDEDEFLKEAIEKDIPTLGFCLGAQLIAKA------------------------------------------------------------------------------------------------ +----MILFIKHIDI-------EGPGTIG-------DFLEDNKISSAIVDLSNK-----------------------------------DNLPELK--TLQMVISLGGPMNVYEYPFLADENVFLKEIIKRDIPFLGVCLGAQLMVKA------------------------------------------------------------------------------------------------ +-TGPRVLVVEHQES-------CPPHLVG-------RWLTDAGCTLSVCRPYAG-----------------------------------DALPA-L-TSYDAVLVLGGEMSANDVPWLGPLKAGIRDAVDAGTPLLGICLGHQLIAAA------------------------------------------------------------------------------------------------ +---MTILVIEHEDE-------APIGILG-------ERWQEVGHVLDIRRPYLG-----------------------------------DDQPAYL-PEHDALVVLGGYMGANDHGWLTQTKALLADTTRGEQPVLGICLGHQLLTVA------------------------------------------------------------------------------------------------ +-MSGRVLVVEHDAE-------CPAALMG-------TWLTEAGCTLDVWRPYAEG---------------------------------AGELPG-P-ASYDGLLVLGGPMGADDHGWLGPVKELLREVRGSGLPTLGICLGHQLIASA------------------------------------------------------------------------------------------------ +-MSARVLVVEHQES-------CPAHLVG-------DWLEAGGCTLEVCRPYAG-----------------------------------DDVPA-L-TAYDGALVLGGDMGAHDVAWLAPLKERVRDAAAAGTPMLGICLGHQVMAAA------------------------------------------------------------------------------------------------ +---MNFLVLQHLDI-------ESPALIG-------DLLREAGHHLHTAHVYAG-----------------------------------DTLPANT--HLHGIIIMGGPQSAN-LSYIRDELLWLQKRIDEGVPMLGICLGAQLMAKA------------------------------------------------------------------------------------------------ +-GRPRVLVVEHEAG-------APAALLG-------EWLVEAGADLDVRRPYAG-----------------------------------DALPDDL-AGHDALLVLGGSMGAHDHAWLTPTKRLVREAADRAVPGVGVCLGHQLAAAA------------------------------------------------------------------------------------------------ +---MSLLVVQHQRT-------CPPGRFG-------DWLTDAGVELDVRRPDTG-----------------------------------DSLPIDL-SGHDGLLVLGGQMGCRDAPWLPAVRQLITTAAKRATPALGICLGHQLAAVA------------------------------------------------------------------------------------------------ +-SRPAVLVVEHDLE-------CPPAWVG-------TWLVEAGCDLDVRRPYAG-----------------------------------DELPG-L-AAYDGLLVLGGPMGANDHAWLAPVKELLREARDRALPTLGICLGHQLIAVA------------------------------------------------------------------------------------------------ +-ATPRILVIQQEEN-------CPAGLLG-------EVWEDRGVEIDLVRAWEH-----------------------------------W-IAERL-EACDGLLVLGGEMGAHDFAWLTPTKELIRRAEAAAVPQLGTCLGHQLMAVA------------------------------------------------------------------------------------------------ +-TTPCIVAIEHEAM-------CPPGHLG-------AWLSEAGAEVEVCRPYVG-----------------------------------DALPD-L-AAYDALVVLGGTMGADDYWWLPPLKHLVRDAADTGVPTLGICLGHQLVAVA------------------------------------------------------------------------------------------------ +---MSLLVVQHQDS-------CPPGRVG-------QWLTEAGVELDVRRPYAG-----------------------------------DALPDDL-SGHDGLLVLGGEMSCGDAPWLPAVRELIRTAAKGATPTLGICLGHQLASVA------------------------------------------------------------------------------------------------ +-QSLPVLVIEHEEE-------CPPGRLI-------TWAGEAHTDLDIRRCHAG-----------------------------------DQVPTHL-SEHSGYIVLGGAMSAHDYPWLVGTKHLIAQAVAHAVPFLGICLGHQLAALA------------------------------------------------------------------------------------------------ +-SRVTLLVIQPDPA-------DPIDQFE-------PWFVKAGVEWNVVQPHAF-----------------------------------DRVPEEL---ADGLLVLGGDMSSLHYPWLEDIRALYRSAAKLRRPSLGICLGAQLMAQA------------------------------------------------------------------------------------------------ +-KPLTFLVIEHEDE-------CPPAWLG-------EWWEERGVVLRRIQAHAH-----------------------------------DAIPADV-GDADALVVLGGEAGANDYPWLPATRDLIARTVDAGVPYLGVCLGHQLASVA------------------------------------------------------------------------------------------------ +-DPVRITVVQNSPD-------VTLDAFA-------DRLG---PDVRLVRPFDG-----------------------------------DALPEAT-DLGDGFVVLGGQMSAYAAPWLPALRDLLAAAVFSDVPTLGICLGAQLLAVA------------------------------------------------------------------------------------------------ +---MTTLVIQNDPV-------APLGLLS-------RFL----DSPRVLRAWED-----------------------------------PGAPLVEGAPFDSLVVLGGTADAHAWPWLPDLRALIAACAGAGVRVLGVCLGAQLAAVA------------------------------------------------------------------------------------------------ +--MPTVLVVQNEED-------VPLGRME-------GLLIDAGASVRILEAWRE-----------------------------------PLL---VSELPDALLVLGGRMNAYSAPWLPGVRSLINRCIDADIPVLGICLGLQLMAVA------------------------------------------------------------------------------------------------ +--MTRILVVQHEPE-------APGGWLA-------ERWVEHGITIETVRGDLG-----------------------------------DTVPDRL---HDALVVLGGAMNAYEFPWLAPTKALLRTAVADGIPTLGVCLGHQLLGVA------------------------------------------------------------------------------------------------ +--MPRYLVIQHEPA-------APGGWLV-------ERWSELGSAVETIRGDLG-----------------------------------EPIPARL---HDALVVLGGAMNANEYAWLAPTKSLLRAAVADGIPTLGVCLGHQLLAVA------------------------------------------------------------------------------------------------ +-MGARLLVVQHEPD-------APAGWLG-------EWWAAAGVELDVVRADLG-----------------------------------QPLPARLDGGHDGLVVLGGAMGANDHPWLRPTKELLRDTVRGGSPTLGVCLGHQLASVG------------------------------------------------------------------------------------------------ +-GERVVTVIENHPS-------CPLDLLE-------QSMAMVSLEVV--RPYYG-----------------------------------DTLPTSD--VRGGLIVLGGYQSAISCPWLPKVRALLRDCVDASIPTLGICLGAQLLALA------------------------------------------------------------------------------------------------ +-TAAHVTVIENAPD-------APLGSFE-------QHLTAAGLTVRTVRPHAG-----------------------------------EALPALA-DLGAGLVVLGGDGTAYDTPWLPGLRTLLLDAATSGVPTLAVCLGAQLLAVA------------------------------------------------------------------------------------------------ +-MTTTVLIIENDPG-------SGPGRLL-------DWIAQRDLAPVIVRAHAG-----------------------------------EPLPATS--GHAALILLGGGMLPDASPWLPAERELLRTTVERDVPVLGICLGAQLLAHT------------------------------------------------------------------------------------------------ +-EPPRITVLQNSPD-------VPLGLLA-------ATLG---DGVRVVRLDLG-----------------------------------EPVPGVD-AVGGGLVVLGGQMSAYDAPWLPAVRSLLVDAVRANVPALGICLGAQLLAVA------------------------------------------------------------------------------------------------ +-TNPVLTVVQLDAG-------VPLDRFA-------NWLDG--LRVRTVRAYLG-----------------------------------ESVGPVG-EL-DGLLVLGGQMSALD-PGVAATRALLADAVEAGVPTLGICLGAQLLAVA------------------------------------------------------------------------------------------------ +-QPPVLTVVQQGPD-------VGPDLFA-------SWLTG--LDLRIVRADLG-----------------------------------VPVPAVG-AVGDGLLVLGGQMTAFDAPWLPAVRALLVDAAASDVPTLGVCLGAQLLARA------------------------------------------------------------------------------------------------ +-VTVRLTVVQSSPD-------VPLDRFA-------GWWSD--AHVTVLRADLG-----------------------------------DAVPSLE-QVGDGLVVLGGHMSAYDAPWLPALRTLMADAARTGVPTLGVCLGAQLLAVA------------------------------------------------------------------------------------------------ +-SNPRLLVVRNDAE-------DDARRLG-------DWLVEAGADLHVVNADAG-----------------------------------DALPADL-TGYDGVVVLGGAQAA--SPWFPALKALLREAVHERVATLGVCLGGQLLADA------------------------------------------------------------------------------------------------ +--MRTALVIENDPT-------DDLRRLG-------EWLTEAGLELTVLRPHAG-----------------------------------DDLPETL-DDFAALIVLGGDQSAYPAPWFPALEGLFRKAVRNRVPTLGVCLGGQLLASA------------------------------------------------------------------------------------------------ +------MVIENAPT-------WHLGRLE-------TWLIDAGLEPEVLRPHTG-----------------------------------DAIPERV--HHDALIALGGGRGA---AWTPELTALLRTTVADRLPLLAFCSSARSLATS------------------------------------------------------------------------------------------------ +---MRILIIQHSDK-------EHAGGFR-------PLFARDGHEISACIAPDE-----------------------------------IGDVDLS--HFDGLWVLGGPMQVWQLPWLAREIEVIRDAVLVRMPCFGICLGHQLLAHV------------------------------------------------------------------------------------------------ +--MRRVVIVQHEDN-------AGIGRFA-------APLEELGVTVTTVGPGIG-----------------------------------VDVPEAL-GDVEGLIVLGGSPGPNDAPWLPRVRGLIQEALDRELPYLGICLGGQLLAVV------------------------------------------------------------------------------------------------ +-PHDADLGHRSRAS-------CSSGRLG-------QLWRNAGADVVEINAWN------------------------------------HPVPPIV--DADALVVLGGSMSCQDAPWLAPTRQLISRTVRAGTPFLGICLGHQLATVA------------------------------------------------------------------------------------------------ +--MSQALVIGHDAH-------ASLRRLA-------PWFAEYGLDGSIVFGA-------------------------------------NGLPQSL--GYDALIVLGGAPLPDDYPWLPATRRLIGEALARHMPMLGICLGGQLLAYT------------------------------------------------------------------------------------------------ +--MPTALVIGHSKK-------ASLRRLG-------PWFNGQGLDYEV--KFGG-----------------------------------DGLPDSL-DSYAALVVLGGAPLPYEFPWLPATRALAREALEKHVPMLGICLGGQLLAYV------------------------------------------------------------------------------------------------ +--MATILVLEHDPD-------DPVQRLG-------DWLTEAGATLLICRLHAG-----------------------------------EQIPA----EFDAVVCLGGRMNATDTPWLAATKALLRRAIAARTPTLGVCLGAQLMAVA------------------------------------------------------------------------------------------------ +-QAPRVLIVRNAER-------SGPGRLL-------PWLRDEGLAAVEL----G-----------------------------------PEAPADP-AGYDGVVLLGGGFLPDDAPWLPAQRDLTRRAVAEGVPLLGICLGAQVLAVA------------------------------------------------------------------------------------------------ +-PAPSVLVVVNDPD-------SGVGRVG-------PRLRALGLRLAPV----G-----------------------------------DGVPEHP-GGHAGVLLLGGGFMPDAAPWLPRERRLAEAALAGGVPLLGVCLGGQLLALV------------------------------------------------------------------------------------------------ +-AAPRVLVVRNSPR-------SGPGRLL-------PWLREEGLTAVEA----G-----------------------------------AEAVDDP-AGYAAVVLLGGGFLPDDHPWLPAERLLARRAVDQGVPLLGICLGAQVLAAA------------------------------------------------------------------------------------------------ +-DGPKVLVVVNSRP-------SSLRRMR-------PWLEDSGLELVVAYGD-------------------------------------EGLPERL--SFDGLIMLGGGLMPDDAPWLARERELAAEAIAGDIPTLGVCLGAQILAHV------------------------------------------------------------------------------------------------ +--MSTVLVIINAAT-------SPPRRMA-------GWLADAGLDVVTVHAP-------------------------------------DGVPDSL--GVDGLVMLGGGFMPDEAPWLRAERELAARAVDADLPTFGICLGGQLLADI------------------------------------------------------------------------------------------------ +-MSAAVLVIVNSPT-------SGPRRLR-------RWLSEAGIEVIEKLGQ-------------------------------------DGLPETL--GVNGLVMLGGGFMPDDAPWLAQERELAREAILRDLPTLGICLGAQILTHV------------------------------------------------------------------------------------------------ +-GKPRVLAVQSGRD-------SGPARFG-------AWLAEAGLVVEVVAGCDG-----------------------------------DPLPPPL--GHDALLVLGGGYLPDDAPWLPATRALVTRALETEVPLFGICLGGQMLAAV------------------------------------------------------------------------------------------------ +--MTRLLVIVNDIE-------SQPGLLT-------QWMISENVEFDLRIGGST-----------------------------------LPKPAEL--AYDGLIMLGGGFMPDEAPWLADEAELVRHALDTDLPQFGICLGGQLIAHV------------------------------------------------------------------------------------------------ +--MTKVLVVQNGRG-------GGPRRFG-------AWLEQEGVTLDVVHAYAG-----------------------------------APLPRRL--DHAAILPLGGSPMPDDMPWLAAVRELVAEALERDVPVFGVCQGGQLLAHV------------------------------------------------------------------------------------------------ +-KMPRVLAVQNGTN-------GGSGRFG-------EWLDAAGVAVDVVTAFDG-----------------------------------SALPSRL--EHDGLIVLGGGYLPDDAPWLPATRALVEQALGRSVPFFGICLGGQMLASV------------------------------------------------------------------------------------------------ +-TRPTAIVVQNGPK-------GGPGRVG-------EWLAAEGIALDVVHGYQ------------------------------------EPVPERL--EHDAVIVLGGGYLPDAAPWLAATRTLVRQALDTDTPVLGICLGGQLLAHV------------------------------------------------------------------------------------------------ +-TATTALVIQNFPR-------GGPGRWA-------PWLAAAGVTPVLVRAYDG-----------------------------------EPVPRRL--DHAALLVLGGGYLPDEAPWLAPTRALALQALDEGTPYFGICLGGQLLAQV------------------------------------------------------------------------------------------------ +-GRPTAVVVQNTRS-------GGPGRVG-------VWLREAGIRLHVLRPYEG-----------------------------------EALPRTL--DGRPLLVLGGGFLPDDAPWLPATRRLVAQALDESTPVLGICLGSQLLAQV------------------------------------------------------------------------------------------------ +-LRPRILLVQNDAA-------SGPGRLI-------DWIADAGADSSLVAAHAG-----------------------------------EPVPTDT-AGYDAVVLLGGGLLPDEAPWLADERALTTRAVEDGTPLLGICLGGQLLAHT------------------------------------------------------------------------------------------------ +-SAPRVLVVEHENG-------TGPAQVG-------ERLTARGLDLVIRRPWAG-----------------------------------DLLPLTP-DDYDGLLVLGGSMGPYDAPWLSAAGDLLRQAVARDMPTLGICLGMELLTVA------------------------------------------------------------------------------------------------ +-MTRPILVIEHTAV-------DPPGRVG-------TWLRDEGLELEVIRPYAG-----------------------------------EAQPNDL-SRYAGLLVLGGDVGAYDAPWLPATRALLAHAVDEQLPTLAICLGHQLLAVA------------------------------------------------------------------------------------------------ +-----MLVIEHQKN-------AGLGQLS-------DRLIENGLTLETVGPDAG-----------------------------------APVPESL-DGYDALIVLGGAMGPTEAPWLPATRKLLVDGVELGVPTLGICLGAQLLATA------------------------------------------------------------------------------------------------ +-APATVTVIEHEAD-------VGLGFFA-------GWLADAGLRCEVHRPYRG-----------------------------------DRIPERA-R--DGLLVLGGSAAAWECGWLPATRALLARSVAEGVPTLGICLGAQLMTLA------------------------------------------------------------------------------------------------ +--MRELIVIEHEAE-------AGLGFFA-------GWLEGAGVRCEVVRPYKG-----------------------------------EPVPERA-G--DGLLVLGGAASAWDYGWLPATRALMARSVESGVPALGICLGAQLMTIA------------------------------------------------------------------------------------------------ +-RRVRILAIEHERG-------TGPERFG-------EWLVEAGAEVVVTRPYLG-----------------------------------EVIPALGNGSFDALIVLGGSAGPTENPWFPEVRELLRRSIAGEFPSLNICLGGEMLAVA------------------------------------------------------------------------------------------------ +-MHTRIVLIEHENG-------TGPQRFG-------RWLQDAGAQTEVIRPYKG-----------------------------------EKVPEPEKG-GDGLIVLGGAASACENPWFRATKKLLVASAEGYFPSLNICLGGQMLAVA------------------------------------------------------------------------------------------------ +-GVATAFVIENDPT-------EDARRLG-------EWLTEAGLQLHLARPHAG-----------------------------------DELPADL-DGYAALVVLGGGQQAYPASWLPQVEALSRKAVRHRVPTLAIGLGAQLLATA------------------------------------------------------------------------------------------------ +-ERPRVLVIQHEDG-------VGPGMLG-------AELAAAGLELRLVHPWAG-----------------------------------DEVPGTL-AGHGALLVLGGSIGHGDAPWLPAVRALIREAAADGVPLLGICLGAQLTACA------------------------------------------------------------------------------------------------ +-TGQAVLVVQHEAD-------AGPGLVG-------EHLVRTGLRLHVIRAWKG-----------------------------------EALPETL-GGHTGLLVLGGSVNCEDAPWLPRVRALVREAVAGEVPLLGICLGGQIVAHA------------------------------------------------------------------------------------------------ +-VGPVVLVVQHEED-------AGPGLVG-------EHLLLAGLRLDVVRAWRD-----------------------------------EPLPDDL-RGHAGLLVLGGSVNCRDAPWLPRVRTLVREAVAGGVPLLGICLGGQIVADA------------------------------------------------------------------------------------------------ +MITMKMLIFI-----------APNDYKEETLEKLKLIFGKRDVKYAVSSYSKKECIGYHGA----------------------VCMPDVNTNTVSSNDYDGFVIVDGKGISYKLYDFRPLLDLILKFNASKKQVCAIGNSVKVLARA-------NIIKDMKISTPDEEEAKR-----------------LVLLFHGIPT------QEAYEINENIST-------------------------- +---MKFLVFM-----------PPKGFRDETVSAIKLLFGRWDIDCAMSSYTSKECVGKHGA----------------------TYRPDLNTSSASPENYDGIVLADGPGIDYKLYEFRPLLDLLVGFNTQKKYIIGIDNAIKIISRA-------NIIRDKKVSAPREEDARK-----------------AVQLFRGVLS------KEPVESSDNLIT-------------------------- +--GRTVGILFD------------EGSDSAELERLIKAVEDAGGTAFTVAPKVGGLSLEGG-K----------------------MKADGQLAGSPSVLFDAVALVLTAEAAKKLSRNGAAVAFVVDAFSHLKAIGLNDGAKTLLDRA-------GVEAG------------------------------------------------------------------------------------ +--GRHFGILIA------------DGSDAAAFVKLKKAITDAGAKAVIVAPKVGGAKLSDGKV----------------------MKADRQLAGSPSQLYDGVAVVLSEDRTTALLKESAAVEWLTNAFVHLKAIGHTTESHPLLKKA-------GVEHD------------------------------------------------------------------------------------ +--GRKIAVLVA------------DGVSGAAVASLKARAEKARASAKVIGPRANGVTSAEGES----------------------VPVDHTLSSVGSVLFDAVYVPQGD--VDALQADPAALLFICEAYKHYKPIGAGGTGAMLVAAA-------ARAAG------------------------------------------------------------------------------------ +--TLRVGVIVA------------NGYDGPSAQYIINQFKQVGLQPVIVSERLGIVQGTSNGH----------------------WEVNDTFLTGSPLLYDGLLLIGGKMD-DH--FLNKASSFVVESYNHFKPIGSFQNGSSIIQSL-------NIEGK------------------------------------------------------------------------------------ +--TLRIGVIIA------------HGFDEQKTNQILDQWKRMGLQPVIISEKLGKVRGANSTE----------------------WRVEGSFLTGSPLLYDGLYVVGGDAE-GT-TFNWKTKSYVVETYNHYKPIGLTHKGATIIQPL-------GIIGQ------------------------------------------------------------------------------------ +--TQKVGVLIG------------NGFNSNEVTNVLNYLKQNGVFIEIVSEKLGTVTGADGTQ----------------------IKVNKTFITTSPYLLDSLYVVGGRAK-NEAKFHQDVMNFVRVAFSHYKPIGVATTAQSQ---F-------QIKAS------------------------------------------------------------------------------------ +--SRKVAILVA------------NGVDGKAVEAMKAALTAKGAHAKVLGPTSAPVKTADGKS----------------------LPVDASAEGLPSVAFDAVFVPGGADSVKALSTDGVALHFILEAYKHLKAISVAGEAKDLLSLL-------RLEED------------------------------------------------------------------------------------ +--TLKVGVLASLS---------ADGSVGQGK-ELKDAFAADGVLVTVIAER-----LADG--------------------------VDLTYAQADATAFDGVIVASGAQGPSPLYPAGRPAQLVIDSYRWGKPVGGVGNALNESAPL-------GVKAG------------------------------------------------------------------------------------ +----------------------------------------------------------------------------------------------------------------------EVLAWIEHQARTSMYVTSVCTGSLVLAAVGKREGRGGLLDGVRATTHWMFLD-------------------QLRQMGVEAVK-----GERVVRDVVIYTGGGVTAGIDFAFA------------- +----------------------------------LDLLEALGARLEFFSP----------------------------------------LTDPMLPAVDSVYLPGGYPELDALSANRAFAAALLRHAQAGKPLYAECGGLLYLLESV------TDMRGRRA--------------------------------------------------------------------------------- +----------------------------------LDLLRNMGAELSFFSP----------------------------------------IHDSQLPDADSLYLPGGYPEHLALAANTSMQAAIRAHHNAGKPMLAECGGMLYLLDAL------TDVEGVRA--------------------------------------------------------------------------------- +----------------------------------LMRLRQAGAELVFFSP----------------------------------------LSDSRLTDVDGLYFGGGYPEAPTLSKNKSLLNYIRDLSYKNIPIYAECGGLMYLSKGI------KLVEGEFF--------------------------------------------------------------------------------- +----------------------------------LGALEEKGAELVYFSP----------------------------------------LNDLVIPEVDGLVFGGGFPELFQLSSNESMKESIREANEKGMPIYAECGGLMYLCESIHDFEGAV---------------------------------------------------------------------------------------- +----------------------------------INQLKEYG-DVEFFSP----------------------------------------LRHFSAPSADLLYLPGGYPELSPLSANKSMIQSIRDYALSGGRVLAECGGMMYLCNSITGMDGIS---------------------------------------------------------------------------------------- +----------------------------------IDLLERAGVNIVRFSP----------------------------------------LHDRVLPDCQMIWLGGGYPEAAELAANTAMLKHLRAAHQRGVAIYAECGGLMYLGSTLEDSGGEI---------------------------------------------------------------------------------------- +----------------------------------LDYLTALGAELIPFSP----------------------------------------LHDTALPEAAGVIIGGGFPELEPLAGNQPMLTDLRRRVAGGMPVYAECGGLMYLTRGITDLEGRT---------------------------------------------------------------------------------------- +----------------------------------LEALETAGAELVFINA----------------------------------------LHDSQLPKVDALFIGGGFPEMEQLANNHSLKTEIREAIENDRPVYAECGGLMYLARQLT-WQEKT---------------------------------------------------------------------------------------- +----------------------------------TELLTAAGARVMPFDP----------------------------------------LRDERLPGTGGLVIGGGFPEAPELSANEPLRTEVAKLAATGAPIAAECAGLLYLARSLD-----G---------------------------------------------------------------------------------------- +----------------------------------AELLSAAGAEVVTFDP----------------------------------------LNDEALPGTAGLVIGGGFPEAPELSANEPLRAAVAAFAAVGGPVAAECAGLLYLARSLD-----G---------------------------------------------------------------------------------------- +----------------------------------AELLAAAGARVAEFDP----------------------------------------LVD-ALPGTDALLLPGGFPETAELSANEVVRRQINELAAAGAPVHAECAGLLYLVSELD-----G---------------------------------------------------------------------------------------- +----------------------------------AELLRAAGAEVVEFDP----------------------------------------CVD-SLPGSGAVVLPGGFPEPAELSANTTARQQIYELAAAGAPVHAECGGLTYLVSDLD-----G---------------------------------------------------------------------------------------- +----------------------------------LELLSDMGAELVFFSP----------------------------------------IHDRHLPDLDGLIFYGGYPEGMELEENHVMRRETASAVSSGLPCMAECGGFLYLHREMEDKDGIF---------------------------------------------------------------------------------------- +----------------------------------LDLLRQLGAEILYFSP----------------------------------------LHDRKLPKLQGLLIGGGYPEAQALSENTGMLQDIRKQIAGGLPYLAECGGFMYLHESMEDMEQKH---------------------------------------------------------------------------------------- +----------------------------------LELLQDLGAELVPFSP----------------------------------------LRDRKLPGVSGLLLGGGYPEGEALEENQVLREEIRRGVGRGLPTVAECGGYLYLQTALEDQEGGL---------------------------------------------------------------------------------------- +----------------------------------LEMLQAYGATLVYFSP----------------------------------------LAGECVPDVHGLYIGGGFPEAAELARHEKVKRSVAEAIQRGLPTLAECGGFMYLTEGIETTDGQY---------------------------------------------------------------------------------------- +----------------------------------KEFLSEIGIPLISWSI----------------------------------------YDDEEIPEASSLIIPGGFPEAEQISNSRKSLNSLRKFRKNG-FIYAECGGMMILGDLIKDENGNN---------------------------------------------------------------------------------------- +----------------------------------FDALEENGAKLKFFSP----------------------------------------LNDSEVPDCDTIYLGGGYPESKKLSNNKSMIESIRNFD---GKIYGECGGLMYLTNSID-----G---------------------------------------------------------------------------------------- +----------------------------------LEALESNNADLIYFSP----------------------------------------LHDEEVPDVDGLYIGGGYPEARELEANQSMRHSMKQFHQEERPIYAECGGLMYLTRSIN-----Q---------------------------------------------------------------------------------------- +----------------------------------IDRMQ--G-QIIRFSP----------------------------------------VFGSE-LQADIVYLPGGYPEARQLHRRKRLMEQLRDYVENGGKLLAEGGGMALLGQTLTARGGTA---------------------------------------------------------------------------------------- +---------------------RNEGTELTDFLVTHGVLRRADAEVRAVAPRRGRVRLYPALEVE-------------------IDQDLAAFDRAYPDGADYVIVPA-----LDDADDPVINDWLQRQAARGARIVAVCAGTLI---------------------------------------------------------------------------------------------------- +----KVLFAFS------------HGVEDQEVYYFYNYLIDRGTKQITLGIDYNGLESDVIL-SDF-----------YKPSYRIPKQFTMDINKVNFNDYDVIYIPGGLPSSSALRNNQLFIQNLKSFYENEKLVIFMCSGTEVFIQS-------GIISGLNLTGSPAS--------------------------------------------------------------------------- +---KRVALILS---GLGNE----TGTDLYDAVSLMVNLNNLGVNVNFYSLPDQMIESSRISRGKI-----------------------NDLSTLKPSEYQGIFLPGGNGVATNLTNNEILENALIQFHQDKKPIVTLGLAGIIAAKV-------FIKYSPRLT-------------------------------------------------------------------------------- +----------------------------------LDTLRALGAELCFFSPLANQPV---------------------------------------PAGAHALYLPGGYPELPALAGNTASRESICAHHAAGRPLVAECGGMLALLESLTDAAGHGLLPGPRGNGGPPRQPRY----------------------------------------------------------------------- +----------------------------------LDLLNALGAQLKFFSPLDDTSL---------------------------------------PE-ADSLYLPGGYPEMERLAANQSMHQAIHVHYAAGKPILAECGGMLYLLSTLTDHHGKNLFSGKAT-----MQRNL----------------------------------------------------------------------- +----------------------------------LDCLTALGAELIFFSPLSDTTL---------------------------------------PE-VDSLYLSGGYPELETLSQNMSMRQAICEHINANKPVVAECGGMLYLCRTLTDKHGQGVLAADAK-----LQARL----------------------------------------------------------------------- +----------------------------------LELLAAMGAQLAFFSPLAGEPL---------------------------------------PM-CDAVWLPGGYPEAAVLAQRREFFAQLATHVAASKPLIAECGGMMTLFDTLTDTQGAALLPGRIV-----MQPRL----------------------------------------------------------------------- +----------------------------------VDWLLEQGAKLAWFSPLAGEPV---------------------------------------PA-ADALWLPGGYPEAEQLAQSASL-VSIKAFIESGKPVLAECGGTMLLGETLIDNQGKSVLPFESR-----MQSKL----------------------------------------------------------------------- +----------------------------------LDWLTGQGAKLVFFSPAASEPV---------------------------------------PQGVDAIWLPGGYPEARQLSQSTTW-HSMRTYADAGTPILAECGGAMLLGQSLVDVNGDGVFPYISI-----MQTRL----------------------------------------------------------------------- +----------------------------------LDLLREAGAEIAFFSPLAGEPL---------------------------------------PD-CDAAWLPGGYPELAALSQRTDLHAALRAHRDAGKPLLAECGGLLFALDTLADRDGNGLLPGSAA-----LQPWL----------------------------------------------------------------------- +----------------------------------IALLRAAGAELAWFSPLAGDAL---------------------------------------PA-CDAVWLPGGYPELQTLSQQSSLHAALRAHRDAGKPLLAECGGLLYLLDSLAGRDGAGLLRGHAT-----LQARL----------------------------------------------------------------------- +----------------------------------LDLLREAGAELRFFSPLAGDAL---------------------------------------PE-CDAAWLPGGYPELHALSDSDSLRSALHEHVHAGRPLLAECGGMLYALDSLAGTDGKGLLRGQAT-----MQTRL----------------------------------------------------------------------- +----------------------------------LDVLREAGADIRFFSPLAGEAL---------------------------------------PA-CDAAWLPGGYPELLTLSQHDALRRALRKHVDAGRPLLAECGGMLYALDSLADVEGTGLLRGSAA-----MQARL----------------------------------------------------------------------- +----------------------------------LELLAAAGAHLQFFSPIAGDAL---------------------------------------PD-CDAVWLPGGYPELQALSQRRDLAVALRAHCAQGKPLLAECGGMLFLLEALTGKDGVGLLPGTAA-----LQARS----------------------------------------------------------------------- +----------------------------------LQLLIDAGAECIAFSPIAGDSL---------------------------------------PD-CDAVWLPGGYPELPALSANAALREALHAHRDAGKPILAECGGLLYALDRLSDREGNGLLRGHAQ-----IQPRM----------------------------------------------------------------------- +----------------------------------LDLLSEAGAELVYFSPLAGERL---------------------------------------PD-CDAAWLPGGYPELPALSGSDGLRRDLHAHRDAGKPLLAECGGLLYLLDTLADKDGDGLLAGDAA-----LQPRL----------------------------------------------------------------------- +----------------------------------LDLLRAAGAELKYFSPLAGDSL---------------------------------------PD-CDAVWLPGGYPELAALSGNQALRRDLHAHRDAGKPLLAECGGLLYLLDALTDKDGEGLLAGSAV-----LQPRL----------------------------------------------------------------------- +----------------------------------LDVLRAAAAELRFFSPLAGDPL---------------------------------------PE-CDAVWLPGGYPELGALSARTDLHMALRTHHGAGKPLLAECGGLLFALEALADRDGVGLLPGHAR-----LQPRL----------------------------------------------------------------------- +----------------------------------LEVLQMAGARIVFFSPLAGDPL---------------------------------------PE-CDACWLPGGYPELQTLSQQKSLHATLAAHVDAGKPLLAECGGLLFCLDTLADHQGRGLLRGHAR-----LQERL----------------------------------------------------------------------- +----------------------------------LDQLEALGAELAFFSPLADAPL---------------------------------------PAGCDALYLPGGYPEAARLAANATTARAIAAHVAAGKPVVAECGGMLYLSDSLTDVDGAGLVPGDAT-----MQRRF----------------------------------------------------------------------- +----------------------------------LALLEALGASLGFFSPLADEAL---------------------------------------P-DCDALYLPGGYPEAARLAANRRSAAGIASHVAAGRPVLAECGGLLYLCETLGTVDGTGLLPGAAT-----MQRRF----------------------------------------------------------------------- +----------------------------------LALLLALGARIATFSPIADEPV---------------------------------------PADADALVLPGGYPEAAALARARRTAASIRAHVAARLPTLAECGGMLYLMDGLTDIEGQGALPGESI-----MQPKL----------------------------------------------------------------------- +--MKTILIIAP------------EGGMLLEATGIADIFTRANYQVTLATTQPHHVI--HGA-SGF------------------KLLAEHRLCDLAPTPFDTIMVTGRG---LTEEEGDQVTQWLSQAAPYARRVVSVCGGALHVAPA------------------------------------------------------------------------------------------------ +-ETRQVAVILA------------DGFDAEQFLAVSQGLKSAKCVAKIVAPRKGKIESSKKTEDT-------------------AVEADSTFFTTKSVVFDGVIAIGGAPSVQTLAASGACLAFINQSFRHYKPIGAVDDALSLLLDV------------------------------------------------------------------------------------------------ +-DTKSVAILLN------------G-PANEKLTEWVKTLAQYNINYSIIAKKIHPIN-------T-------------------VLKVTDTFDTADSSLFDAALLISTEP--------TPVLEFIEITFKHFKSLALALS-NQALEQS------------------------------------------------------------------------------------------------ +-KGRQVALLVS------------D-VDAADVLAAMQALKAEGVHAKLLASHMGNLL--ASDGST--------------------LPIDGTIEGNPSITVDGVVVPNGNL-------DGAARHYILEAYKHLKPIALSGD-RRFKPQL------------------------------------------------------------------------------------------------ +-KTLRVGVIVG------------E-FDGPSTQYILEEFKGAGLQPVIVHERQGVVR--GTGNVE--------------------LKVDDSFLTGSPLVYDGLFIVGGQQ--------KYTRSYAIETYNHFKPIGATPT-AAVIQPV------------------------------------------------------------------------------------------------ +-YTLKVGVLIG------------D-FDANEVGEVLKYLTRQGVRYSIISDRLGVVT--GNNGVQ--------------------LTATDTFITTDAVLFDSLYVVGVKA-------NTQIVNYINEAYRHYKPIGFAVT-TTFFNMS------------------------------------------------------------------------------------------------ +-MTQKVGVLIG------------EGFNGKEVKETLDTLKENGVMVEIIAEKLGSVTG---EDGT-------------------VLEPTKTFLTVHPSLFDAIYIAGGKS-QNQLKFDQIIFDFVRMQYMHLKPIGVSSGKDSYIA-------------------------------------------------------------------------------------------------- +-YTRTVAVLIG------------NGFNGQEVTNALNVLRKYGVWVDIVSENLGTVIG---DDGT-------------------KINVDKIFTSTYPVLFDSIYVVGGNT-KNQEKFNQSVMHFINEQYKHYKPIGIATTAQSYIQ-------------------------------------------------------------------------------------------------- +-ETLKVGVLVA------------D-FDDAMTKDILTRLQQADVRLVIISEKQQAVK--GKNMNR--------------------LEVNDSFLTASPLLYDALLVVGGEN-------KAEMKSYVREQYMHYKPIAFLKQ-AFIAKEL------------------------------------------------------------------------------------------------ +-ETRKVAVLLD------------D-VDAEQVETIRTALEDEGARVTIVSKLLGDRT--AASGDP--------------------IEADEAHATTSSVLFDAAIVPGGRD-------QGDATHFVAELFKHKKPIAAVGE-VDLLDGL------------------------------------------------------------------------------------------------ +-EGRHVAILFA------------E-SALAEIEHLKQSITAAKGRVTLLAPKIGAIAVKG---G--------------------TLTADAQLAGSPSVLFDAVALVLSEE-------DSAAVGFVADAYAHLKAIGTSPGA-PLLDRA------------------------------------------------------------------------------------------------ +-KGRKLGILVT------------D-ADGAVVDALKAAAKAAEASVMVLAPKVGAVKLAG---GT-------------------EIAADAQLDGAPSVTFDALAVVASAE-------HKKALDWLSDGFAHLKAIAHTAEA-PLLDKA------------------------------------------------------------------------------------------------ +-KGRKVGILFD------------E-SNKELIDEIVAGVEKAGGTSFLVAPKIGPLKVKG---G--------------------TLKADGQLAGTPSVMFDAVVAILMPE-------DVGAVAWFADAWFHCKTIGACGGTEHLLPKA------------------------------------------------------------------------------------------------ +-KARKIAILAH------------D-ANEASIKAVQAWAESESAVADVLTPRPGPVL--SQQGTV--------------------IPSDGMQKAEPSIAYDAVVIVDGDN-------DGIATHYLLEAYKHLKPIVFLGD-GQLIEDL------------------------------------------------------------------------------------------------ +-DTLKVGIYSD------------D-D-DFDFKSLTEKIEKSKAKAEIIQKTLKETK----D--G--------------------VRVDHRYDTVHPVLEDSLIIVVPEK-------MKNVKEFAEETYKHYKPLWIIGD-KDILDKD------------------------------------------------------------------------------------------------ +-RARRLALLVQ------------D-FSMQEFETIQDWAIKEGVILECISDHSGFVT--SDTNAT--------------------LPLKGNYQSEPSIFYDATVVLGGTK-------EGYLMHYIMETYKHLKPLVFLNG-ERLITTM------------------------------------------------------------------------------------------------ +-DTKSVAVLLA------------G-VDAAQVKAWVQALADKKVNYSLVGKKAYTL--------G-------------------DLKVKETYDTVDSSLFDAAFLVSAAS--------DDVLEFIENTYKHFKPLALHLH-DSVLDQC------------------------------------------------------------------------------------------------ +-DTLKVGIILS------------E-YNLDEFNTMIKALNVAKTMPEIIGCNLSPIK--GSDGTS--------------------QLPKHSLLSADPVLFDAICVLGSG--------KMRAKMFIEETYKHFKPILVSQS-TMLL-KP------------------------------------------------------------------------------------------------ +-EGRKVAILVA------------D-SNAEMLEKYKSAITAAKATPFIVAPK-ISITLNN---GE-------------------TIAADGQLAGSPSVLFDAIVSIIMPE-------VSEAIAWFKDAHAHLKAIAYCGATEFILIPQ------------------------------------------------------------------------------------------------ +-RTRTVAVLAR------------D-VDGRHLTSVKEALTERGAVVEVVAPLAGSLT--TTDGGP--------------------HPADRALPTVASVLYDAVLLPGGPV-------DPDVVRFARDAYRHGKPVGALGS-VGVLAAV------------------------------------------------------------------------------------------------ +-KGRKVGCLVA------------D-TDLEMVKSLKAAAKRLGADFAVIAPKVGGATSAD---GK-------------------TIEGDFQLAGGPSVLFDTVFLALSED-------ESGAVAWVSDAFAHLKVIGTTAGA-PLLTRA------------------------------------------------------------------------------------------------ +-EGRKIGILIN------------E-SDKGKIERLKKMIKEHNGVPAVIAPRAHGIKLSD---GS-------------------KVDADGILAGMPSVLFDAVAVVLSNK-------ESAAVQWVQDAYAHLKAIAYTKES-RLLKKG------------------------------------------------------------------------------------------------ +-MGRNVGILIT------------N-TDGSVLDKLVSEIKKNNARATLIAPTVGGIRLKD---GS-------------------MRNADVQLAGSPSVLYDAVALVLSSE-------QSAAVQFVMDAFSHLKAIGASSAA-PLLNKA------------------------------------------------------------------------------------------------ +-SGRRIGIYLV------------PGYTYSQVVPLFAAFEAAGCMVKFIGPTLGPIKAANG---E-------------------SFTAEFTFEGCRSTFFDAIVIAGGPD------DIGRLIHAVREAYMHLKAIGVLGNA-QWVVDT------------------------------------------------------------------------------------------------ +-VSRKVAILVA------------D-VDGKAVEAMKAALTAEGAHAKVLGPTSAPVK--TADGQS--------------------LPVDASAEGLPSVAFDAVFVPGGKA-------DGVALHFILEAYKHLKAISFAGE-KELLSLL------------------------------------------------------------------------------------------------ +-DGLTIALLTT------------GAD-VKIAESLRKEFENKKVNVRLVGPVLEPKQ-----------------------------GVTVTYSGADGALYDGVIIVGNMV------TNGRPMRIAEDAYLYGKPVGGVGPGDRAMKAV------------------------------------------------------------------------------------------------ +-EGRMVGILVG------------D-SDGARVEALRRAATDAGAAVKIIAAHVGQVKLAN---GK-------------------MLKVDKQLAGTPSVLFDAVAVVVSED-------ESAALDFVHDAFGHLKAIASDAGG-ALLDAV------------------------------------------------------------------------------------------------ +-RTRKVAILVD------------N-YCPIAVQAMTDMLKGAGAVPEIVGVTLAPIT--GRSNAK--------------------LEPGKSLITASALAYDAVLIPAGD--------NADARTFINEALHHCKTIGAMEE-IDLLKVT------------------------------------------------------------------------------------------------ +-ITLRVGILIG------------HNFDDEEVGDVIHALKKHGIFIDFISEKLGTITG---VDGT-------------------KITVSQTFLTTNPNLYDALYVVGGSS-KREKKFNQEMMNFSIEVYKHYKPIGVATNAEKYLP-------------------------------------------------------------------------------------------------- +-RQKRIAIIKL------------DGTPESEIETIKKRFESGDALVFIIDHRGL--------------------------------------DAMRSTLFDATFLPLTNEQSYRV--HGRVKHWIRESTGHLKPLLINGSYLSLVKQV------------------------------------------------------------------------------------------------ +-DGRQVGIIAD------------D-TDADK---LIKGIDDAGMVPLVIADHAGRLGK-KN---D-------------------GATVQRTTFNTRSIEFDAVIAAADL--------APEIAVLLGETFRHLKAIAAIGD--QKLVKR------------------------------------------------------------------------------------------------ +-DGRIIGIVTD------------GADALDAVRTVRRTILDSGMVPLVIAASGGTLGD-GGD-GD-------------------AVSVQRTFATARSIEFDAILLAGAPAAADAQG-DPRVLLLVTEAYRHGKALGAWSE-GRALDAA------------------------------------------------------------------------------------------------ +-KGRKVAILAA------------P-VAAAQVQAVQDALAAEGAMAEVVGPYLGALG--D---SG--------------------VEATKTFANSGSVLFDAVYVPGGAA-------QGDARKFIDEAYKHGKAIAASAE-ADLVMAT------------------------------------------------------------------------------------------------ +-RNRMVAILAA------------D-VDGAQVDAIKQALEAEDAKGEVLGQHLGMLD------GG--------------------AEAKKTISNSHMVLFDAVIVPGGAQ-------DGDAHAYLLEAYKHGKPIAAYGE-QQLLQGS------------------------------------------------------------------------------------------------ +-EGLVVGILAD------------DSLSVAELSSLQASFAPLSVMFQVVAPHQGLL-------NT-------------------GVLANSSYITTSSIFYDAIVIGGAETATP----RDTLTTFVMEAFGHGKPIAAIGNGG------------------------------------------------------------------------------------------------------ +-AGLTVAIIAD------------DILTMSDLQAMQPMLFSQQVGFDIVAPHVGML-------AS-------------------SVNATSSYTLTSEVMYDAVFIGSSANGSIS--TSMAASHFILDAYAHGKPIAALGSNAR----------------------------------------------------------------------------------------------------- +-AGLTVAVVAN------------DMFSEEDLSAMMPLLEAQQVSLAIVGPRIGML-------AT-------------------GVNATASYITASSVFYDAVFVGSSINAT----GAGDAMEFIKQAYGHGKAVGVFGGSNLTDAVG------------------------------------------------------------------------------------------------ +-DSLTVAILAS------------ADEGLAAARNLAEQLAQLNVTVDIVAERL--LE-----------------------------GVDGTYASANAAAYDAVVLSAGAALVMKGGTAHRPRRIVADAYRYGKPVAIFGDFGGEEEVG------------------------------------------------------------------------------------------------ +-ATLRVGVLAS------------SNDSLAQARELKEQLSKEGVVVTVVGEVL--KE-----------------------------GVDQTYSAADATGYDAVVVTDGAEGLLTG-GAGRPGQILVDSYRWGKPVAAVGENGQAL--------------------------------------------------------------------------------------------------- +-RGLNVGILAS------------IDKSMTQAAELARQFTSLGVFANVVAETL--IT-----------------------------GVNYTYSAADASFFDGIIVAQGAESIFSAN-LHRPAQIIHSGFNWGKPIAAIGSASVLT--------------------------------------------------------------------------------------------------- +-SSRTVAIIIS------------DGFDYLHYSSMKNALEAAGAFVSTIGPKRQPIMSW-S--YD-------------------SVIPDHHFEGMRSTLYDSICIPHGKE-------QGRVIHWIREAFGHCKAIGATGEA-KLVEKA------------------------------------------------------------------------------------------------ +-EGRKVGIFIM------------DGFDVKALTAIQTAIVGAKAMAMLVGEKQ-KI--KST--DG-------------------IHKCQFTFDTCRSTHFDAIVIVGGSG------DVGRLKHAAIEAYGHQKAILVQGQA-PWVTDV------------------------------------------------------------------------------------------------ +-ATRMVAILIA------------DGYDQVAYNGMKAALTAAGALPFTISPRRNKIYADGEDRGP-------------------GVVADHHLEGQRSTMYDSVFVPGGAK------SNGRAVHWVREAFGHLKAIGGTGEA-SFIKQA------------------------------------------------------------------------------------------------ +-DGRQVAVLIN------------S-ADLGT---LLDTLFDDGVTPLIVSDKGGTVTT-D---GA-------------------EVSVSRTYLTARSIEFDAVVVVNPP--------IPEVATMLGEFERHKKAIILAGPDDVALGAA------------------------------------------------------------------------------------------------ +-KSNKVAIIVT------------E-S-SEKLNELIATFLSEDIVVELVSNKQGIVS--G-------------------------YEIHETFATTSSVLYDGVYVTGAFQ-------QSKAEQFIKQAYQHCKTIGYTKN-SFL-QP------------------------------------------------------------------------------------------------- +-PGHSVAVLVN------------G-INEETLKSYAKTFVDNKLNYAFVGQTAKDLN------NN-------------------EIGITETYSTASSTVFDSVIVLSDGK--------LTAVDFAEMSYNHKKPVVITEE-KNILQSN------------------------------------------------------------------------------------------------ +-QTRRAGIIVG------------E-FDGNSLGDVLDKLKEAGITADFISERQGTIK--GQDGYK--------------------AEANHTFTTTHAVLYDGIIIAGGTG-------KRDASEFINDTFKHYKTIGVTAG-NDLFAQS------------------------------------------------------------------------------------------------ +-KGRRLGLLVS------------E-SDFSLIDGIDTRMKMEEAELVVIAPKIQGLRTES---SG-------------------WRKPSQCLQSTLAAWYDAVALLLSTA--------PALVSFVQDSYYNYKFIAFSGDV-PLMERL------------------------------------------------------------------------------------------------ +-MGRMVGVLVT------------D-TEDAQVEAIRSAAEAAGVRVQIVAEKRGGVTLES---GT-------------------HLMADGQLAGTPSVMFDAVAILPSEE-------LAPAKDFAADAFAHLKAIVVSAPA-ALLEAV------------------------------------------------------------------------------------------------ +-KQRKIAVLVH------------N-CNPNSINEIKKWADSENAIAEILGPSAAPVK--DVNNNP--------------------VEVDGSQTGEPSVTYDAVVIIDGEN-------DGVAKHYVLESYKHLKPILLLKD-AELVDFL------------------------------------------------------------------------------------------------ +-EGRTVGILVA------------D-TDAKDLDGVVKGVTDAGGYALIIAPRIGSIRLSN---GD-------------------LLTAGAQLFGQPSSLLDAVALVLTPE-------ESAAVIWIADAFAHLKAIGHNGSS-RLLEIS------------------------------------------------------------------------------------------------ +-KGHVIGILIA------------D-SDGAAVDKLKAAISKAGAVSKVIAPKIGGAKGAD---GV-------------------LIPADGQLAGTPSVTVDAIAVVLSDT-------EAAAVQFVMDAFGHLKAIGATDAA-PLLDKA------------------------------------------------------------------------------------------------ +-EGKLVGCLIA------------D-SDTESILALETAIAEAGAEMKIIAPKIGGATATD---GS-------------------TIEADFQLAGGPSVLFDCVFLALSQD-------EAAAVAFVHDAFSHLKVIGATPES-ILLDKA------------------------------------------------------------------------------------------------ +-KGRKLGIYIA------------E-ADADVVKALKDNAQNAGGMVEIVAPHVAGAKLSD---GT-------------------MMEADEKIDGGPSVVYDAVAVIMSEA-------DKPSVDFVNDAFAHAKFVAYVPAV-PLFETA------------------------------------------------------------------------------------------------ +-QGRKVGILAE------------N-ANTATIKALKEWLISKGAMAEVVASKFGDLD--G-------------------------IKVDKSYITTASVLYDSIVIVDGED-------NGETIHFINEVYKHCKSIATIGK-QKLLSQT------------------------------------------------------------------------------------------------ +-YTQKVGVLIG------------DGFNGPEVANVLQFLQQNGVFIKIISDNLGTVTG---SDGT-------------------KLKVDDTFLTSSPYLVDSLYVVGGNV-KQQEKFMQEVLDYVHHAYKHYKPIGVATSGQSYIH-------------------------------------------------------------------------------------------------- +-KGRKLGIILT------------E-SHFSLLTHLEKATKKAGGTVDLIAPTLSHFKTKK---K---------------------ITPQHSFETAVSARCDAIAILARAN--------LKLVTFLRESFYHNKFIGYISEL-DLFKCL------------------------------------------------------------------------------------------------ +-RSRKIALIAT------------P-VNPVLVEQVRDALQAAHAVPTIVAPTLAPIG-------G--------------------IVPEATLVGMPSVMFDAVFVCGGDG-------SADARHFVREAFKHLKPIAAVGS-RQLLSAA------------------------------------------------------------------------------------------------ +-EGRVVGILVA------------D-SDGDVIKELEKAIVKAGANIKIVAPKIGGVKLAD---GT-------------------MQTADKQLAGAPSALFDAVAVILSDQ-------ESVAVDFVTDAFVHLKAIAFDSGG-VLLKKA------------------------------------------------------------------------------------------------ +-VGRQVAVLVA------------D-VDGTAASALRDSLVAEGAVVELLAARDGAVR--TEDGDA--------------------VTVDRAYTTVSSVLYDAVAVVGGTE-------DGTARHFLLEAYKHHKPLAAIGA-GSLLTAP------------------------------------------------------------------------------------------------ +-ATLKLAVLAG------------N-FNAVELNEVLQAAKEAGVTPEIISEHLGMIK--GSDGSE--------------------LEVGQTLLTSDSVLYDAIYVAGGQA-------MKESANFVRDAYNHYKTVAVGKE-LNLLAGA------------------------------------------------------------------------------------------------ +-EGRKIAVLVH------------P-AATDNIEPIHQWALKENVMLDFLTPTPAPTT--TIEDDM--------------------IPSDGMQQAEPSVLYDAVIVLDGNN-------DGVACHYVIEAYKHLKPVVLLGD-AELLEHL------------------------------------------------------------------------------------------------ +-ESRRIAALVC------------D-VDDTGIRKLASALSAEGALLDLIGPAEGAIR--GESGHS--------------------VDVSVGLSSTASVLYDAVIVPGGDI-------NGSAKHFLLEAFKHHKAVAAFGA-VEVLRRN------------------------------------------------------------------------------------------------ +-ESRKIAVLAA------------D-VDVTGVQSFVEAMRRRGAVAEVLAPTGGGEL-AGGSGGQ--------------------LGVDRAITTMASVLYDAVVVPCGPE-------DGYAMHFITEAYKHLKPIGAFGA-VELLPKA------------------------------------------------------------------------------------------------ +-KARRIAILTA------------D-VSDEAFTKVKKVLCEMDALVQIIAPRHGFVT--TASGDQ--------------------YPVDDSLLTTASVIFDAVYIPGGD--------HAGAIHFVAEAYKHCKPFGADGN-VDLLQKA------------------------------------------------------------------------------------------------ +-MGRKIGFITA------------D-ADASAISALKAKLEAGNAVVEIIGTSLSPVT--VSDGSS--------------------LIPKHSLTSTASVCFDALYISAGED-------PHLVLNFINEAYKHCKAINFGEG-EPLYMNS------------------------------------------------------------------------------------------------ +-KGLRVAVLAA------------A--SAGNAAGLRDGLEAEGVVVTVVAESQ--AA-----------------------------GVNATYSASDASGFDGLLVAPGAETFFSGNGLGRPAELVLDAYRWGKPVGALGSA------------------------------------------------------------------------------------------------------- +-KGLNIGILAS------------TSNSMSQAAQLAKSFSAEGLFVSTVAESL--QP-----------------------------GVNVTYSAADAHAFDGLVVAAGAEAIFTGE-LGRPMEILKNGYGWGKAIGAVGSA------------------------------------------------------------------------------------------------------- +-TGFTVGILTS------------VSSSIIQASQLANSFTSYGLKTLIIGESL--QS-----------------------------GINRTYASMDASLLDAVVVTDCVEKLFNSGILGRPSQILVDAYRWGKPIGSVSSDKIF---------------------------------------------------------------------------------------------------- +-DNRVVGLFVC------------G-CDLDAVTAAKKAVEDAGMVPQLVAPAGGPLGG-RE-----------------------DLMVDVTAINAASIMFDAILVADHPE-------PRNLAAVVGEAWHHGKAVGGWGD--AGFVAH------------------------------------------------------------------------------------------------ +-DGRTVAVLID------------D-ATAAAVGEVIAALTEARVRPLLVAARGGVVED---D--A-------------------DLMVDRTFATMRSVEFDGLILLGGP--------DPRVDLLVEEMWRHGKAIAAVGT--SVLQRT------------------------------------------------------------------------------------------------ +-ATRQVAVLAA------------D-VDAAGVRALRSALTERGAIVEVIASHGGMVHADGGDGDT--------------------LPVDRTLMTVASVLYDGVVVAGGQT-------NGEAVHFVLEAFKHAKPVAAFGA-VSLLRIA------------------------------------------------------------------------------------------------ +-KGRKVAVIVT------------D-SDASMVEKIRQAVAKAGGRLAVVAPKIGGIKPRN---GK-------------------GLTPDHALAAAPSIFFDAVVLAPSRA-------DAGAVDFVRDAYGHLKVIGVFDGG-ALIEQA------------------------------------------------------------------------------------------------ +-AGRKIGVVVT------------D-TPTESLAGLRKAAEAAGATVELIGPTAGGVQLGRR--K---------------------VPVDHAIAGAPSVLFDAVALLPSAD-------RKCAKDFVADAFGHQKFVAHSSDA-PLLTAA------------------------------------------------------------------------------------------------ +-EGRKLGLLLG------------E-ADAAAVKRLTKAVDKAGGTVEVVAIAVGGAILSD---GS-------------------TLPAKQAVAGGPSVLYDAVAIIAGSE-------EPPARDFLTDAFAHYKVIGLAGAT-ALVDAA------------------------------------------------------------------------------------------------ +-KTRRIAIITT------------D-CDEKSIEAMKKALTEGDAVVKIVAPTLGKIK--GKNGTF--------------------IDVDESFLTFSSVLFDALYFPSGAK-------HMEPLNALDEAYRHCKPIAFDED-LELWNAS------------------------------------------------------------------------------------------------ +-AGLRVGVLAT------------VDSSLSQARDLKSKFDQEGVSTIVVAERY--AD-----------------------------GVDAIYSGIRANAFDGLVITKGTEALFGAN-RGRPTQTLEDSYNWGKPVAAVGSG------------------------------------------------------------------------------------------------------- +-TTRRIAILLA------------DGFDFNQYTTMKEVLSERGAFVFTIGAQRQGVTAESG--Q--------------------KVIPDHFFSGVRSTLFDAVYVPGG--------KNGVFKHWISEAFAHLKAIAGANEA-PFIEKQ------------------------------------------------------------------------------------------------ +-TGRVIGIFAG------------P-ADLGGVEKLAGAIEAAGAIARVIAPTGGVIAK-GKT----------------------TRIVERTLLTTRSVEFDAVVVAAGLG------FDIKLTILLQEAFRHCKTIAAWGD--QVLTAA------------------------------------------------------------------------------------------------ +-EGRKLGILVS------------D-ADAAIVDALIAAVGAEKGVYEIIAPHITGATLSD---GA-------------------LRVAHQKVDGGPSVLYDAVAIVLSEA-------DKTAKDFVSDAFAHCKFIAYTDPA-ALFEKA------------------------------------------------------------------------------------------------ +-KGCKLGILLT------------D-ADAAIFNALVKAVDKEGAVYEVVAPKIGGVTLSD---GT-------------------AVAAKQKIDGGPSVLFDAVAVVASEE-------DAAAKDFVTDAFAHCKYIGLTAQA-ALFEKA------------------------------------------------------------------------------------------------ +-DGLKVGLLAS------------VKPSIAQGAKLQVAL-SVGVDVVVVAERM--AN-----------------------------NVDETYSASDAVQFDAVVVADGAEGLFGADSAGRPLNILLDAFRFGKTVGALGSGDALES-------------------------------------------------------------------------------------------------- +-VGRKLGLFVH------------DGFDFGIASGIKTAFAAMGIIVAVVGPRKDKIKSSTD--GT-------------------FLEAQFTFETCRSTLFDAVFFIGGSG------PQGRWLYAAREAFMHFKTVGASGSA-PWLCKY------------------------------------------------------------------------------------------------ +-KGRKLGIFIS------------D-IDPQQLENIEKCFTQEGANVERIALKVGGIKDKN---GT-------------------KIEAHHQIDGGQSVLFDAVALIINVS-------SAPLRDFINDAYAHYKFIGYNEAS-ELLSAL------------------------------------------------------------------------------------------------ +-AGLNVGILTT------------TTNSLEQATSIAQSL-RSGVNGTIIAETL--SA-----------------------------GVNTTYISSDAVLFDGIIVCDGTDTLFSEAAPQRPLSIVRDAFFYGKPIAGIGAGKAFMN-------------------------------------------------------------------------------------------------- +-DGLQVAVLIS------------GQKSLDAARQLQALFKHSGIDVVIIGPTYNPKA-----------------------------GIVSTYAGADASLYDAIVALEGFP------GPGRPQQLLIDAYRYGKTVGVVGSNDQIVKSV------------------------------------------------------------------------------------------------ +-EGLKVGYLTS------------SVN--DAPGKLKEAL-EQKVGLTIVAEQL--GA-----------------------------GIDQTYSATSAVNFDAIIVDGGAESLFMPA-AGRPLQILQDGYNFGKPVAVAGASKTLTA-------------------------------------------------------------------------------------------------- +-DGRKVAVLAD------------D-TPAQP---AVQAIVDAGMTPLVAATTGGALAA-GDSTGQ-------------------DVPVSRTYTAARSIEFDAAIVVSLP--------TPETNTLVEELTLHLKAIAVLDNVPQHALRK------------------------------------------------------------------------------------------------ +-DGRKVAILVD------------D-TPAQA---AVKAIVDAGMAPLVTTTTGGTLKP-SDAGAQ-------------------ALPVSRTYSAARSIEFDAAIVVALP--------TPETNTLIEELTRHFKAIAVLDSIPQHALRK------------------------------------------------------------------------------------------------ +-EGRVVGIVAS------------H-TDAAVIERLVADANLAGMRPLLVAPVGGTLAD--------------------------GSPVDRTLLTARSIEFDALVIADVLSSDGARVTDPRFVLLLQEAYRQSKAIVALDGV-RF-PDA------------------------------------------------------------------------------------------------ +-AGRQIGIVVG------------E-VDQATAAAIGQAIRAADVVPLIVGPHGGV-----IG----------------------DLVVNRTYANAASIEFDALVLVGDLPAPDAMVADPRVVKLVGEAWRHSKAIGAVGDG-GALADA------------------------------------------------------------------------------------------------ +-KSRRIAILIA------------DGYDHASYSAVHAAIKAASALPFTIAPKRQKVKAADGS--S-------------------EAQPDHHLNGMRSTMFDAVVVPGGEQ------AIGLARFWVREAFGHDKAIAALGHG-QLVEAA------------------------------------------------------------------------------------------------ +-KSRRIAILLA------------DGFNLAEVQALRAAFKVGQATTWIIGPRRGKVYPSGQTVE--------------------GLQADHHYEGQRSTLFDAFIIPSGVE------HNGRTIHWIREAFGHCKAIGAIGEG-TFLKEA------------------------------------------------------------------------------------------------ +-KTRRIAILVA------------DGFNGAEVLALRAALKAGMATTFLIGPRRGKIYPAGQKIE--------------------GMMADHHFEGQRSTLFDALLIPSGLE------HNGRTVHWIREAFGHCKVIGAIGEG-AFLRDA------------------------------------------------------------------------------------------------ +-KAKNVAILLG------------PGSDVCQANDMYKFLTDQGAIVDFIGPVLGEF--------D-------------------GLPIKQTYLTTTSVMYDGVFVPTGEVMTFEKLMYGEPVNFILDTYRHGKPIALAGKAVALLKAA------------------------------------------------------------------------------------------------ +-RTKKVAIFTA------------PGIDVSEAKTMFDFLDKEGAYPEYVGFKLGEQ--------D-------------------GIVTNHTFLTTSSVLYDAVYVPSGEKSAFQLLTYNEPAVFLLDAYRHGKPIAASGRATTLLKAA------------------------------------------------------------------------------------------------ +-VSRRIAILIA------------DGFNAVEIQAVRASLTNSKAICYIIGPRRSHIHI-----FP-------------------MPGQDTSLGGQRSTPFDAPYIPSGTVHTNTLANNGRVVHWHLTRFVVLAIDLLRGVV--RL--P------------------------------------------------------------------------------------------------ +-QGRCVGLLVA------------D-ADAGLLAALQRALAKVGARTVLVAERRGGPTLAT---GD-------------------RVEASQALDAAPSCLFDHVLVLGDGP-------LPAARAWLQDAWRHLKVIGLDSAA-QLADAA------------------------------------------------------------------------------------------------ +-KGRKVGVLLL------------D-FDPALLTALQDSVNSEKASLFLVANSIAGATDSS---GK-------------------LVPADGALSGSPSVFFDSVAILAPKD-------AAATTEWLEKAFNHRKVMAYSSGA-TILERA------------------------------------------------------------------------------------------------ +-SGKKIGLLIT------------A-VDDKLLTAIREAAHAEGAMLSIVAPHAGEIETSG---GK-------------------KVMPEHFLAGAPSVLFDCVIV--APA-------QADAVDWIRNAFAHLKVIGYTEAA-GLFDKA------------------------------------------------------------------------------------------------ +-DGRVVGVVVD------------P-VLPRDLEATLAELETARLRPLIIAPQGGEVV---------------------------GRPVDRTFATAQTFELDGILLAGAPAAVDARPGDPRVIALVQGCWRHAKPIAAWQD--QVVEDS------------------------------------------------------------------------------------------------ +-AGRKIVMLAA------------D-VVGESLLAVHAALFAQGAVPRIAAPRIGPVQ--TADGVA--------------------LQADVSLENEPGFLFDALVLPDGEA-------DGHTYEFIRDQYRHCKSILALGT-LQLLQAA------------------------------------------------------------------------------------------------ +-KGRKVAIFVA------------D-CAGQSAADVHAALLNAGAVPRFVAPRIGPVA--TVDGVV--------------------IEADASLENEPAFLFDALVLPDGDA-------DGHSMEGIRDQYRHCKTILALGT-ADLLDLV------------------------------------------------------------------------------------------------ +-RGRMVGIYIM------------P-YD-STVSELMGALTAAGAVPLTLSAKGGPVP--DASGSS-------------------TTTPSFTFSASSSTQFDALFIPGGRK-------NVPALVQIAEGFKHLKAIAAVNE-VEVVQRL------------------------------------------------------------------------------------------------ +-PRGENTILIG------------DGTTQSPSPLSN-RGNSHECSAHHNGTKRQPIFADHEDRGA-------------------GVIPDHNYIGQRSTLLTPRSYPVARI-------LGAFRHWIAEQFGHCKAIGATGEA-DLIAQV------------------------------------------------------------------------------------------------ +-ETRRVAILLS------------DGFASADFASMMAALKDARAFPCIIGPRRSSINPAD-ASAQ-------------------SVTPAHHFEGLRSTMVDAVFVPDGSH-------NGRAVQWVREAFAHCKAIAATGRG-ELVREA------------------------------------------------------------------------------------------------ +-KSRRVAMIVA------------DGFEMGVFTAVRAALKAEGATTWVIAPRRGMIFPAGVHPTG-------------------GLLADHHLEGQRSTMFDAIFVCPGTR------SNGRAVHWVREAFGHLKPIGVLGDA-SFLQQA------------------------------------------------------------------------------------------------ +-EGRRVAILIA------------DGFDLGQVTEMRTALAAQKAVTFIVGERRGPIKAAGQEEEE-------------------GLGADFSWESGRSTLFDAIYVPGGA-------GSGRVTHWVREAFEHLKPICATGEG-DFIQQA------------------------------------------------------------------------------------------------ +-KSRRVAILIA------------DGYDKFFVTAAKAALTAAGAVPLIIGPRRNYIYANGEERGA-------------------GIWADHHFEDQRSTMFDGLLLPPGAH-------NGRVVHWIRESFGHLKPIGAVGAA-DVVKHA------------------------------------------------------------------------------------------------ diff --git a/examples/testdata/raptorxeg/195600.contactmap.txt b/examples/testdata/raptorxeg/195600.contactmap.txt new file mode 100644 index 0000000..692e887 --- /dev/null +++ b/examples/testdata/raptorxeg/195600.contactmap.txt @@ -0,0 +1,7301 @@ +PFRMAT RR +TARGET 195600 +AUTHOR RaptorX-Contact +METHOD DCNN +MODEL 1 +MAPKKVLLALTSYNDVFYSDGAKTGVFVVEALHPFNTFRKEGFEVDFVSE +TGKFGWDEHSLAKDFLNGQDETDFKNKDSDFNKTLAKIKTPKEVNADDYQ +IFFASAGHGTLFDYPKAKDLQDIASEIYANGGVVAAVCHGPAIFDGLTDK +KTGRPLIEGKSITGFTDVGETILGVDSILKAKNLATVEDVAKKYGAKYLA +PVGPWDDYSITDGRLVTGVNPASAHSTAVRSIDALKNHHHHHH +8 103 0 8 0.998214 +103 135 0 8 0.998019 +101 133 0 8 0.997684 +135 216 0 8 0.997469 +7 102 0 8 0.997331 +104 136 0 8 0.997259 +7 46 0 8 0.997204 +9 104 0 8 0.997099 +6 101 0 8 0.997096 +7 99 0 8 0.996998 +6 45 0 8 0.996793 +5 44 0 8 0.996682 +136 217 0 8 0.996652 +102 134 0 8 0.996389 +8 47 0 8 0.996244 +9 48 0 8 0.995879 +37 228 0 8 0.994784 +34 228 0 8 0.994659 +5 99 0 8 0.994659 +134 215 0 8 0.994478 +104 140 0 8 0.994401 +161 197 0 8 0.993548 +162 196 0 8 0.993269 +162 198 0 8 0.992848 +5 100 0 8 0.992820 +6 43 0 8 0.992756 +163 210 0 8 0.991973 +10 49 0 8 0.991773 +48 91 0 8 0.991686 +218 227 0 8 0.991219 +34 224 0 8 0.990999 +210 217 0 8 0.990880 +48 89 0 8 0.990861 +137 224 0 8 0.989803 +209 218 0 8 0.989558 +7 48 0 8 0.988848 +141 164 0 8 0.988727 +4 43 0 8 0.988110 +4 100 0 8 0.987443 +209 227 0 8 0.987366 +105 137 0 8 0.986095 +135 227 0 8 0.985801 +7 103 0 8 0.985629 +163 199 0 8 0.985512 +8 46 0 8 0.985330 +6 103 0 8 0.984982 +102 127 0 8 0.984762 +8 48 0 8 0.984164 +161 199 0 8 0.983796 +6 46 0 8 0.983663 +49 87 0 8 0.983602 +96 127 0 8 0.983495 +158 195 0 8 0.983464 +141 217 0 8 0.982827 +30 224 0 8 0.982296 +8 45 0 8 0.982123 +162 197 0 8 0.981783 +137 218 0 8 0.981506 +102 135 0 8 0.981324 +135 231 0 8 0.981233 +9 103 0 8 0.981182 +216 227 0 8 0.978091 +30 105 0 8 0.977851 +106 139 0 8 0.977808 +104 135 0 8 0.977736 +47 88 0 8 0.977377 +133 214 0 8 0.977039 +101 132 0 8 0.976830 +6 38 0 8 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0.922950 +209 226 0 8 0.920969 +101 135 0 8 0.920406 +30 106 0 8 0.920038 +121 143 0 8 0.919594 +105 140 0 8 0.918121 +147 156 0 8 0.918053 +51 90 0 8 0.915751 +48 88 0 8 0.915685 +52 87 0 8 0.915473 +139 168 0 8 0.914816 +160 215 0 8 0.914103 +96 123 0 8 0.911400 +208 218 0 8 0.910880 +9 120 0 8 0.909889 +218 224 0 8 0.909812 +104 134 0 8 0.909176 +46 89 0 8 0.907719 +158 196 0 8 0.906939 +158 194 0 8 0.906668 +162 211 0 8 0.903595 +133 216 0 8 0.902541 +163 217 0 8 0.901223 +161 210 0 8 0.900127 +121 146 0 8 0.900092 +163 198 0 8 0.899482 +37 232 0 8 0.899319 +192 198 0 8 0.898449 +10 31 0 8 0.897071 +144 217 0 8 0.895506 +144 162 0 8 0.894198 +5 43 0 8 0.894126 +138 220 0 8 0.893329 +49 89 0 8 0.891740 +47 85 0 8 0.891320 +164 208 0 8 0.890550 +128 134 0 8 0.887065 +133 235 0 8 0.886796 +54 87 0 8 0.886682 +27 106 0 8 0.884591 +120 143 0 8 0.884365 +124 134 0 8 0.884052 +34 105 0 8 0.883175 +30 138 0 8 0.881826 +102 132 0 8 0.881784 +34 137 0 8 0.881183 +92 119 0 8 0.880235 +127 134 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0.000100 0.000100 0.000100 0.000100 0.000100 0.000100 diff --git a/examples/testdata/raptorxeg/195600.png b/examples/testdata/raptorxeg/195600.png new file mode 100644 index 0000000..51ace06 Binary files /dev/null and b/examples/testdata/raptorxeg/195600.png differ diff --git a/examples/testdata/raptorxeg/models/0README b/examples/testdata/raptorxeg/models/0README new file mode 100644 index 0000000..2f480cb --- /dev/null +++ b/examples/testdata/raptorxeg/models/0README @@ -0,0 +1,11 @@ +----------------------------------------------------------------- +Explanation of files in seqid_models.zip, +where seqid is a number assigned by RaptorX to the query sequence +----------------------------------------------------------------- + +0README : This README file. +seqid_model_X.pdb : The predicted five 3D models for the input sequence in PDB format, where X ranges from 1 to 5. +seqid.model_summary : The summary file contains the energy score from CNS_solver for each predicted 3D model. + +In this package, all files can be opened by WordPad on Windows or vi on Linux. + diff --git a/examples/testdata/raptorxeg/models/195600.model_summary b/examples/testdata/raptorxeg/models/195600.model_summary new file mode 100644 index 0000000..dd52217 --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600.model_summary @@ -0,0 +1,5 @@ +195600_model_1.pdb 1467 +195600_model_2.pdb 1549 +195600_model_3.pdb 1568 +195600_model_4.pdb 1587 +195600_model_5.pdb 1595 diff --git a/examples/testdata/raptorxeg/models/195600_model_1.pdb b/examples/testdata/raptorxeg/models/195600_model_1.pdb new file mode 100644 index 0000000..fe7d84e --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600_model_1.pdb @@ -0,0 +1,2358 @@ +REMARK FILENAME="17_195600_5.pdb" +REMARK The macromolecule has 243 residues +REMARK Trial structure 5 of 10 structures +REMARK Molecular dynamics scheme : cartesian; cartesian; minimize +REMARK High temperature dynamics : +REMARK temp: 2000 steps: 1000 time(ps): 3 +REMARK 1st cooling stage : +REMARK temp: 2000->0 steps: 1000 time(ps): 5 temp step: 25 +REMARK 2nd cooling stage not used: +REMARK a total 36450 steps of minimization +REMARK VDW scale factors 20 20 0.01 0.003 0.003; 3E-03->4; 1 +REMARK 1070 NOEs in 3 class(es) with scale factors of 10; 10; 10 +REMARK averaging function(s): cent, sum, hbnd: cent +REMARK 0 3-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 1-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 carbon chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 proton chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 diffusion anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 susceptability anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 188 dihedral restraints with scale factors of 5; 50; 50 +REMARK 0 planarity restraints with a scale factor of NA +REMARK NCS restraints not used. +REMARK =============================================================== +REMARK bond, angles, improp, vdw(<1.6), dihed +REMARK violations : 29 198 25 6 309 +REMARK RMSD : 0.0175 3.448 1.737 23.669 +REMARK =============================================================== +REMARK noe, cdih, coup, oneb, carb-a, carb-b, +REMARK violations : 117 12 0 0 0 ----- +REMARK RMSD : 0.525 2.266 0.000 0.000 0.000 0.000 +REMARK 0.2/2 viol.: 249 49 0 +REMARK =============================================================== +REMARK dani, sani +REMARK violations : 0 0 +REMARK RMSD : 0.000 0.000 +REMARK .2/.1 viol.: 0 0 +REMARK =============================================================== +REMARK Protons violations, rmsd +REMARK all : 0 0.000 +REMARK class 1: 0 0.000 +REMARK class 2: 0 0.000 +REMARK class 3: 0 0.000 +REMARK class 4: 0 0.000 +REMARK =============================================================== +REMARK overall = 17929.2 +REMARK bon = 868.149 +REMARK ang = 5724.32 +REMARK imp = 348.781 +REMARK vdw = 8640.32 +REMARK harm = 0 +REMARK noe = 1438.17 +REMARK coup = 0 +REMARK oneb = 0 +REMARK carb = 0 +REMARK prot = 0 +REMARK dani = 0 +REMARK sani = 0 +REMARK cdih = 73.4884 +REMARK ncs = 0 +REMARK =============================================================== +REMARK DATE:15-Jan-2017 12:31:14 created by user: RaptorX +REMARK VERSION:1.3 +ATOM 1 CB MET 1 20.013 12.300 8.919 1.00 0.00 C +ATOM 2 CG MET 1 19.299 10.925 9.041 1.00 0.00 C +ATOM 3 SD MET 1 19.397 10.158 10.681 1.00 0.00 S +ATOM 4 CE MET 1 20.748 8.998 10.443 1.00 0.00 C +ATOM 5 C MET 1 18.204 14.095 8.867 1.00 0.00 C +ATOM 6 O MET 1 17.057 13.678 9.064 1.00 0.00 O +ATOM 7 HT1 MET 1 19.854 12.753 11.547 1.00 0.00 H +ATOM 8 HT2 MET 1 18.694 13.993 11.566 1.00 0.00 H +ATOM 9 N MET 1 19.021 13.144 11.063 1.00 0.00 N +ATOM 10 HT3 MET 1 18.261 12.434 11.051 1.00 0.00 H +ATOM 11 CA MET 1 19.385 13.506 9.660 1.00 0.00 C +ATOM 12 N ALA 2 18.507 15.051 7.978 1.00 0.00 N +ATOM 13 H ALA 2 19.438 15.339 7.859 1.00 0.00 H +ATOM 14 CA ALA 2 17.521 15.739 7.124 1.00 0.00 C +ATOM 15 CB ALA 2 17.855 17.222 7.030 1.00 0.00 C +ATOM 16 C ALA 2 17.333 15.145 5.700 1.00 0.00 C +ATOM 17 O ALA 2 16.228 15.259 5.154 1.00 0.00 O +ATOM 18 N PRO 3 18.387 14.514 5.075 1.00 0.00 N +ATOM 19 CD PRO 3 19.818 14.469 5.462 1.00 0.00 C +ATOM 20 CA PRO 3 18.249 13.932 3.719 1.00 0.00 C +ATOM 21 CB PRO 3 19.665 13.430 3.422 1.00 0.00 C +ATOM 22 CG PRO 3 20.514 14.402 4.129 1.00 0.00 C +ATOM 23 C PRO 3 17.201 12.805 3.539 1.00 0.00 C +ATOM 24 O PRO 3 16.286 12.671 4.361 1.00 0.00 O +ATOM 25 N LYS 4 17.348 12.015 2.458 1.00 0.00 N +ATOM 26 H LYS 4 18.096 12.176 1.842 1.00 0.00 H +ATOM 27 CA LYS 4 16.474 10.879 2.057 1.00 0.00 C +ATOM 28 CB LYS 4 16.438 9.746 3.117 1.00 0.00 C +ATOM 29 CG LYS 4 17.801 9.172 3.503 1.00 0.00 C +ATOM 30 CD LYS 4 17.668 8.076 4.555 1.00 0.00 C +ATOM 31 CE LYS 4 19.023 7.575 5.049 1.00 0.00 C +ATOM 32 NZ LYS 4 19.787 6.798 4.030 1.00 0.00 N +ATOM 33 HZ1 LYS 4 19.965 7.397 3.199 1.00 0.00 H +ATOM 34 HZ2 LYS 4 19.234 5.964 3.745 1.00 0.00 H +ATOM 35 HZ3 LYS 4 20.693 6.491 4.436 1.00 0.00 H +ATOM 36 C LYS 4 15.047 11.330 1.676 1.00 0.00 C +ATOM 37 O LYS 4 14.261 11.735 2.547 1.00 0.00 O +ATOM 38 N LYS 5 14.753 11.303 0.368 1.00 0.00 N +ATOM 39 H LYS 5 15.422 11.006 -0.287 1.00 0.00 H +ATOM 40 CA LYS 5 13.447 11.703 -0.192 1.00 0.00 C +ATOM 41 CB LYS 5 13.631 12.485 -1.502 1.00 0.00 C +ATOM 42 CG LYS 5 14.256 13.867 -1.345 1.00 0.00 C +ATOM 43 CD LYS 5 14.450 14.539 -2.701 1.00 0.00 C +ATOM 44 CE LYS 5 15.056 15.934 -2.574 1.00 0.00 C +ATOM 45 NZ LYS 5 14.120 16.933 -1.977 1.00 0.00 N +ATOM 46 HZ1 LYS 5 14.594 17.856 -1.907 1.00 0.00 H +ATOM 47 HZ2 LYS 5 13.837 16.611 -1.031 1.00 0.00 H +ATOM 48 HZ3 LYS 5 13.277 17.020 -2.579 1.00 0.00 H +ATOM 49 C LYS 5 12.525 10.496 -0.428 1.00 0.00 C +ATOM 50 O LYS 5 12.939 9.501 -1.038 1.00 0.00 O +ATOM 51 N VAL 6 11.296 10.587 0.100 1.00 0.00 N +ATOM 52 H VAL 6 11.030 11.381 0.603 1.00 0.00 H +ATOM 53 CA VAL 6 10.271 9.535 -0.018 1.00 0.00 C +ATOM 54 CB VAL 6 9.817 8.991 1.421 1.00 0.00 C +ATOM 55 CG1 VAL 6 9.123 10.071 2.263 1.00 0.00 C +ATOM 56 CG2 VAL 6 8.968 7.716 1.306 1.00 0.00 C +ATOM 57 C VAL 6 9.083 9.979 -0.909 1.00 0.00 C +ATOM 58 O VAL 6 8.553 11.087 -0.744 1.00 0.00 O +ATOM 59 N LEU 7 8.715 9.109 -1.860 1.00 0.00 N +ATOM 60 H LEU 7 9.199 8.262 -1.974 1.00 0.00 H +ATOM 61 CA LEU 7 7.596 9.324 -2.793 1.00 0.00 C +ATOM 62 CB LEU 7 8.045 9.138 -4.257 1.00 0.00 C +ATOM 63 CG LEU 7 8.610 10.332 -5.045 1.00 0.00 C +ATOM 64 CD1 LEU 7 10.140 10.308 -5.107 1.00 0.00 C +ATOM 65 CD2 LEU 7 8.045 10.294 -6.458 1.00 0.00 C +ATOM 66 C LEU 7 6.452 8.360 -2.455 1.00 0.00 C +ATOM 67 O LEU 7 6.686 7.162 -2.245 1.00 0.00 O +ATOM 68 N LEU 8 5.232 8.904 -2.383 1.00 0.00 N +ATOM 69 H LEU 8 5.100 9.861 -2.558 1.00 0.00 H +ATOM 70 CA LEU 8 4.011 8.151 -2.053 1.00 0.00 C +ATOM 71 CB LEU 8 3.255 8.815 -0.881 1.00 0.00 C +ATOM 72 CG LEU 8 3.842 8.806 0.544 1.00 0.00 C +ATOM 73 CD1 LEU 8 4.026 10.237 1.052 1.00 0.00 C +ATOM 74 CD2 LEU 8 2.937 8.020 1.496 1.00 0.00 C +ATOM 75 C LEU 8 3.071 7.990 -3.253 1.00 0.00 C +ATOM 76 O LEU 8 2.969 8.898 -4.087 1.00 0.00 O +ATOM 77 N ALA 9 2.405 6.828 -3.331 1.00 0.00 N +ATOM 78 H ALA 9 2.540 6.127 -2.656 1.00 0.00 H +ATOM 79 CA ALA 9 1.446 6.509 -4.402 1.00 0.00 C +ATOM 80 CB ALA 9 1.727 5.123 -4.984 1.00 0.00 C +ATOM 81 C ALA 9 0.045 6.562 -3.776 1.00 0.00 C +ATOM 82 O ALA 9 -0.214 5.902 -2.759 1.00 0.00 O +ATOM 83 N LEU 10 -0.833 7.366 -4.388 1.00 0.00 N +ATOM 84 H LEU 10 -0.589 7.847 -5.207 1.00 0.00 H +ATOM 85 CA LEU 10 -2.209 7.591 -3.915 1.00 0.00 C +ATOM 86 CB LEU 10 -2.443 9.084 -3.573 1.00 0.00 C +ATOM 87 CG LEU 10 -1.489 10.289 -3.794 1.00 0.00 C +ATOM 88 CD1 LEU 10 -2.088 11.456 -3.058 1.00 0.00 C +ATOM 89 CD2 LEU 10 -0.047 10.105 -3.280 1.00 0.00 C +ATOM 90 C LEU 10 -3.286 7.073 -4.864 1.00 0.00 C +ATOM 91 O LEU 10 -3.126 7.133 -6.090 1.00 0.00 O +ATOM 92 N THR 11 -4.382 6.580 -4.272 1.00 0.00 N +ATOM 93 H THR 11 -4.472 6.595 -3.293 1.00 0.00 H +ATOM 94 CA THR 11 -5.525 5.989 -4.989 1.00 0.00 C +ATOM 95 OG1 THR 11 -6.354 4.705 -3.061 1.00 0.00 O +ATOM 96 HG1 THR 11 -7.170 5.212 -3.044 1.00 0.00 H +ATOM 97 CG2 THR 11 -4.620 3.718 -4.384 1.00 0.00 C +ATOM 98 C THR 11 -6.789 6.860 -4.981 1.00 0.00 C +ATOM 99 O THR 11 -6.962 7.702 -4.092 1.00 0.00 O +ATOM 100 CB THR 11 -5.871 4.578 -4.406 1.00 0.00 C +ATOM 101 N SER 12 -7.650 6.643 -5.984 1.00 0.00 N +ATOM 102 H SER 12 -7.445 5.980 -6.681 1.00 0.00 H +ATOM 103 CA SER 12 -8.934 7.338 -6.148 1.00 0.00 C +ATOM 104 CB SER 12 -9.170 7.650 -7.633 1.00 0.00 C +ATOM 105 OG SER 12 -10.330 8.446 -7.823 1.00 0.00 O +ATOM 106 HG SER 12 -11.114 7.972 -7.535 1.00 0.00 H +ATOM 107 C SER 12 -10.029 6.398 -5.597 1.00 0.00 C +ATOM 108 O SER 12 -11.183 6.809 -5.424 1.00 0.00 O +ATOM 109 N TYR 13 -9.619 5.156 -5.294 1.00 0.00 N +ATOM 110 H TYR 13 -8.680 4.898 -5.430 1.00 0.00 H +ATOM 111 CA TYR 13 -10.477 4.086 -4.752 1.00 0.00 C +ATOM 112 CB TYR 13 -10.518 2.876 -5.722 1.00 0.00 C +ATOM 113 CG TYR 13 -11.065 3.132 -7.133 1.00 0.00 C +ATOM 114 CD1 TYR 13 -12.413 2.842 -7.455 1.00 0.00 C +ATOM 115 CE1 TYR 13 -12.917 3.039 -8.771 1.00 0.00 C +ATOM 116 CD2 TYR 13 -10.230 3.626 -8.167 1.00 0.00 C +ATOM 117 CE2 TYR 13 -10.726 3.826 -9.485 1.00 0.00 C +ATOM 118 CZ TYR 13 -12.068 3.530 -9.775 1.00 0.00 C +ATOM 119 OH TYR 13 -12.554 3.721 -11.048 1.00 0.00 O +ATOM 120 HH TYR 13 -11.862 4.058 -11.623 1.00 0.00 H +ATOM 121 C TYR 13 -9.956 3.607 -3.386 1.00 0.00 C +ATOM 122 O TYR 13 -8.743 3.440 -3.208 1.00 0.00 O +ATOM 123 N ASN 14 -10.875 3.445 -2.422 1.00 0.00 N +ATOM 124 H ASN 14 -11.816 3.657 -2.607 1.00 0.00 H +ATOM 125 CA ASN 14 -10.595 2.963 -1.048 1.00 0.00 C +ATOM 126 CB ASN 14 -9.907 4.046 -0.183 1.00 0.00 C +ATOM 127 CG ASN 14 -9.069 3.464 0.955 1.00 0.00 C +ATOM 128 OD1 ASN 14 -9.584 3.154 2.032 1.00 0.00 O +ATOM 129 ND2 ASN 14 -7.767 3.340 0.724 1.00 0.00 N +ATOM 130 HD21 ASN 14 -7.213 2.969 1.442 1.00 0.00 H +ATOM 131 HD22 ASN 14 -7.404 3.618 -0.144 1.00 0.00 H +ATOM 132 C ASN 14 -11.946 2.542 -0.433 1.00 0.00 C +ATOM 133 O ASN 14 -13.001 2.987 -0.899 1.00 0.00 O +ATOM 134 N ASP 15 -11.896 1.696 0.614 1.00 0.00 N +ATOM 135 H ASP 15 -11.020 1.421 0.944 1.00 0.00 H +ATOM 136 CA ASP 15 -13.052 1.120 1.367 1.00 0.00 C +ATOM 137 CB ASP 15 -13.556 2.046 2.520 1.00 0.00 C +ATOM 138 CG ASP 15 -13.898 3.468 2.068 1.00 0.00 C +ATOM 139 OD1 ASP 15 -15.053 3.708 1.655 1.00 0.00 O +ATOM 140 OD2 ASP 15 -13.012 4.345 2.151 1.00 0.00 O +ATOM 141 C ASP 15 -14.234 0.501 0.577 1.00 0.00 C +ATOM 142 O ASP 15 -14.361 0.728 -0.632 1.00 0.00 O +ATOM 143 N VAL 16 -15.064 -0.301 1.275 1.00 0.00 N +ATOM 144 H VAL 16 -14.886 -0.455 2.229 1.00 0.00 H +ATOM 145 CA VAL 16 -16.271 -1.017 0.760 1.00 0.00 C +ATOM 146 CB VAL 16 -17.433 -0.018 0.286 1.00 0.00 C +ATOM 147 CG1 VAL 16 -18.736 -0.766 -0.051 1.00 0.00 C +ATOM 148 CG2 VAL 16 -17.721 1.004 1.378 1.00 0.00 C +ATOM 149 C VAL 16 -15.956 -2.095 -0.313 1.00 0.00 C +ATOM 150 O VAL 16 -14.968 -1.975 -1.048 1.00 0.00 O +ATOM 151 N PHE 17 -16.813 -3.128 -0.381 1.00 0.00 N +ATOM 152 H PHE 17 -17.580 -3.148 0.234 1.00 0.00 H +ATOM 153 CA PHE 17 -16.708 -4.263 -1.322 1.00 0.00 C +ATOM 154 CB PHE 17 -17.727 -5.370 -0.935 1.00 0.00 C +ATOM 155 CG PHE 17 -17.481 -6.027 0.422 1.00 0.00 C +ATOM 156 CD1 PHE 17 -18.009 -5.465 1.610 1.00 0.00 C +ATOM 157 CD2 PHE 17 -16.767 -7.246 0.513 1.00 0.00 C +ATOM 158 CE1 PHE 17 -17.831 -6.104 2.868 1.00 0.00 C +ATOM 159 CE2 PHE 17 -16.582 -7.897 1.764 1.00 0.00 C +ATOM 160 CZ PHE 17 -17.116 -7.324 2.944 1.00 0.00 C +ATOM 161 C PHE 17 -16.897 -3.849 -2.802 1.00 0.00 C +ATOM 162 O PHE 17 -15.906 -3.706 -3.529 1.00 0.00 O +ATOM 163 N TYR 18 -18.158 -3.665 -3.227 1.00 0.00 N +ATOM 164 H TYR 18 -18.907 -3.805 -2.608 1.00 0.00 H +ATOM 165 CA TYR 18 -18.531 -3.256 -4.596 1.00 0.00 C +ATOM 166 CB TYR 18 -18.907 -4.486 -5.487 1.00 0.00 C +ATOM 167 CG TYR 18 -19.857 -5.542 -4.895 1.00 0.00 C +ATOM 168 CD1 TYR 18 -21.247 -5.505 -5.163 1.00 0.00 C +ATOM 169 CE1 TYR 18 -22.126 -6.498 -4.648 1.00 0.00 C +ATOM 170 CD2 TYR 18 -19.367 -6.604 -4.094 1.00 0.00 C +ATOM 171 CE2 TYR 18 -20.239 -7.601 -3.575 1.00 0.00 C +ATOM 172 CZ TYR 18 -21.613 -7.539 -3.858 1.00 0.00 C +ATOM 173 OH TYR 18 -22.462 -8.500 -3.359 1.00 0.00 O +ATOM 174 HH TYR 18 -21.971 -9.143 -2.840 1.00 0.00 H +ATOM 175 C TYR 18 -19.663 -2.211 -4.564 1.00 0.00 C +ATOM 176 O TYR 18 -19.440 -1.059 -4.953 1.00 0.00 O +ATOM 177 N SER 19 -20.841 -2.626 -4.060 1.00 0.00 N +ATOM 178 H SER 19 -20.917 -3.551 -3.741 1.00 0.00 H +ATOM 179 CA SER 19 -22.101 -1.848 -3.899 1.00 0.00 C +ATOM 180 CB SER 19 -22.471 -1.793 -2.404 1.00 0.00 C +ATOM 181 OG SER 19 -21.451 -1.170 -1.642 1.00 0.00 O +ATOM 182 HG SER 19 -21.341 -0.254 -1.910 1.00 0.00 H +ATOM 183 C SER 19 -22.263 -0.451 -4.570 1.00 0.00 C +ATOM 184 O SER 19 -21.742 -0.237 -5.671 1.00 0.00 O +ATOM 185 N ASP 20 -23.030 0.450 -3.936 1.00 0.00 N +ATOM 186 H ASP 20 -23.497 0.247 -3.099 1.00 0.00 H +ATOM 187 CA ASP 20 -23.284 1.818 -4.423 1.00 0.00 C +ATOM 188 CB ASP 20 -24.790 2.033 -4.676 1.00 0.00 C +ATOM 189 CG ASP 20 -25.334 1.164 -5.806 1.00 0.00 C +ATOM 190 OD1 ASP 20 -25.322 1.618 -6.972 1.00 0.00 O +ATOM 191 OD2 ASP 20 -25.790 0.033 -5.527 1.00 0.00 O +ATOM 192 C ASP 20 -22.774 2.850 -3.407 1.00 0.00 C +ATOM 193 O ASP 20 -22.557 4.018 -3.757 1.00 0.00 O +ATOM 194 N GLY 21 -22.553 2.395 -2.168 1.00 0.00 N +ATOM 195 H GLY 21 -22.705 1.452 -1.937 1.00 0.00 H +ATOM 196 CA GLY 21 -22.080 3.258 -1.090 1.00 0.00 C +ATOM 197 C GLY 21 -20.601 3.153 -0.758 1.00 0.00 C +ATOM 198 O GLY 21 -20.103 2.060 -0.467 1.00 0.00 O +ATOM 199 N ALA 22 -19.916 4.307 -0.800 1.00 0.00 N +ATOM 200 H ALA 22 -20.405 5.123 -1.044 1.00 0.00 H +ATOM 201 CA ALA 22 -18.474 4.494 -0.513 1.00 0.00 C +ATOM 202 CB ALA 22 -18.227 4.616 1.019 1.00 0.00 C +ATOM 203 C ALA 22 -17.460 3.519 -1.161 1.00 0.00 C +ATOM 204 O ALA 22 -16.475 3.123 -0.521 1.00 0.00 O +ATOM 205 N LYS 23 -17.686 3.176 -2.440 1.00 0.00 N +ATOM 206 H LYS 23 -18.472 3.532 -2.910 1.00 0.00 H +ATOM 207 CA LYS 23 -16.804 2.271 -3.218 1.00 0.00 C +ATOM 208 CB LYS 23 -17.434 1.901 -4.579 1.00 0.00 C +ATOM 209 CG LYS 23 -18.052 3.049 -5.408 1.00 0.00 C +ATOM 210 CD LYS 23 -18.632 2.534 -6.721 1.00 0.00 C +ATOM 211 CE LYS 23 -19.249 3.652 -7.558 1.00 0.00 C +ATOM 212 NZ LYS 23 -20.492 4.228 -6.962 1.00 0.00 N +ATOM 213 HZ1 LYS 23 -21.209 3.480 -6.866 1.00 0.00 H +ATOM 214 HZ2 LYS 23 -20.857 4.981 -7.580 1.00 0.00 H +ATOM 215 HZ3 LYS 23 -20.276 4.623 -6.024 1.00 0.00 H +ATOM 216 C LYS 23 -15.397 2.885 -3.391 1.00 0.00 C +ATOM 217 O LYS 23 -14.408 2.169 -3.597 1.00 0.00 O +ATOM 218 N THR 24 -15.356 4.221 -3.282 1.00 0.00 N +ATOM 219 H THR 24 -16.183 4.733 -3.139 1.00 0.00 H +ATOM 220 CA THR 24 -14.143 5.050 -3.361 1.00 0.00 C +ATOM 221 CB THR 24 -14.247 6.149 -4.464 1.00 0.00 C +ATOM 222 OG1 THR 24 -15.487 6.858 -4.333 1.00 0.00 O +ATOM 223 HG1 THR 24 -16.231 6.266 -4.474 1.00 0.00 H +ATOM 224 CG2 THR 24 -14.164 5.531 -5.852 1.00 0.00 C +ATOM 225 C THR 24 -14.000 5.719 -1.986 1.00 0.00 C +ATOM 226 O THR 24 -15.009 6.086 -1.365 1.00 0.00 O +ATOM 227 N GLY 25 -12.764 5.828 -1.501 1.00 0.00 N +ATOM 228 H GLY 25 -11.984 5.501 -2.001 1.00 0.00 H +ATOM 229 CA GLY 25 -12.515 6.439 -0.205 1.00 0.00 C +ATOM 230 C GLY 25 -11.289 7.321 -0.215 1.00 0.00 C +ATOM 231 O GLY 25 -11.167 8.176 -1.101 1.00 0.00 O +ATOM 232 N VAL 26 -10.372 7.103 0.744 1.00 0.00 N +ATOM 233 H VAL 26 -10.517 6.380 1.390 1.00 0.00 H +ATOM 234 CA VAL 26 -9.150 7.917 0.862 1.00 0.00 C +ATOM 235 CB VAL 26 -9.486 9.309 1.534 1.00 0.00 C +ATOM 236 CG1 VAL 26 -9.819 9.167 3.030 1.00 0.00 C +ATOM 237 CG2 VAL 26 -8.417 10.338 1.265 1.00 0.00 C +ATOM 238 C VAL 26 -7.843 7.326 1.462 1.00 0.00 C +ATOM 239 O VAL 26 -7.852 6.602 2.467 1.00 0.00 O +ATOM 240 N PHE 27 -6.749 7.653 0.762 1.00 0.00 N +ATOM 241 H PHE 27 -6.881 8.178 -0.061 1.00 0.00 H +ATOM 242 CA PHE 27 -5.336 7.351 1.041 1.00 0.00 C +ATOM 243 CG PHE 27 -3.049 7.925 -0.134 1.00 0.00 C +ATOM 244 CD1 PHE 27 -2.028 6.955 -0.103 1.00 0.00 C +ATOM 245 CD2 PHE 27 -2.677 9.292 -0.086 1.00 0.00 C +ATOM 246 CE1 PHE 27 -0.657 7.331 -0.025 1.00 0.00 C +ATOM 247 CE2 PHE 27 -1.317 9.682 -0.011 1.00 0.00 C +ATOM 248 CZ PHE 27 -0.303 8.698 0.020 1.00 0.00 C +ATOM 249 C PHE 27 -4.762 8.195 2.207 1.00 0.00 C +ATOM 250 O PHE 27 -3.852 7.738 2.909 1.00 0.00 O +ATOM 251 CB PHE 27 -4.524 7.512 -0.288 1.00 0.00 C +ATOM 252 N VAL 28 -5.306 9.412 2.386 1.00 0.00 N +ATOM 253 H VAL 28 -6.077 9.662 1.830 1.00 0.00 H +ATOM 254 CA VAL 28 -4.830 10.416 3.369 1.00 0.00 C +ATOM 255 CB VAL 28 -5.643 11.787 3.248 1.00 0.00 C +ATOM 256 CG1 VAL 28 -6.930 11.784 4.091 1.00 0.00 C +ATOM 257 CG2 VAL 28 -4.752 12.993 3.592 1.00 0.00 C +ATOM 258 C VAL 28 -4.648 9.984 4.847 1.00 0.00 C +ATOM 259 O VAL 28 -3.706 10.456 5.479 1.00 0.00 O +ATOM 260 N VAL 29 -5.506 9.102 5.378 1.00 0.00 N +ATOM 261 H VAL 29 -6.240 8.760 4.821 1.00 0.00 H +ATOM 262 CA VAL 29 -5.385 8.616 6.775 1.00 0.00 C +ATOM 263 CB VAL 29 -6.708 7.861 7.242 1.00 0.00 C +ATOM 264 CG1 VAL 29 -6.972 6.579 6.424 1.00 0.00 C +ATOM 265 CG2 VAL 29 -6.703 7.589 8.756 1.00 0.00 C +ATOM 266 C VAL 29 -4.092 7.757 6.905 1.00 0.00 C +ATOM 267 O VAL 29 -3.321 7.911 7.868 1.00 0.00 O +ATOM 268 N GLU 30 -3.850 6.938 5.869 1.00 0.00 N +ATOM 269 H GLU 30 -4.484 6.911 5.118 1.00 0.00 H +ATOM 270 CA GLU 30 -2.680 6.045 5.749 1.00 0.00 C +ATOM 271 CB GLU 30 -2.812 5.117 4.528 1.00 0.00 C +ATOM 272 CG GLU 30 -4.092 4.290 4.439 1.00 0.00 C +ATOM 273 CD GLU 30 -4.234 3.586 3.101 1.00 0.00 C +ATOM 274 OE1 GLU 30 -3.648 2.495 2.931 1.00 0.00 O +ATOM 275 OE2 GLU 30 -4.933 4.125 2.218 1.00 0.00 O +ATOM 276 C GLU 30 -1.444 6.933 5.575 1.00 0.00 C +ATOM 277 O GLU 30 -0.376 6.610 6.080 1.00 0.00 O +ATOM 278 N ALA 31 -1.606 8.022 4.814 1.00 0.00 N +ATOM 279 H ALA 31 -2.476 8.197 4.389 1.00 0.00 H +ATOM 280 CA ALA 31 -0.556 9.019 4.550 1.00 0.00 C +ATOM 281 CB ALA 31 -0.959 9.896 3.396 1.00 0.00 C +ATOM 282 C ALA 31 -0.225 9.888 5.770 1.00 0.00 C +ATOM 283 O ALA 31 0.954 10.113 6.061 1.00 0.00 O +ATOM 284 N LEU 32 -1.272 10.318 6.497 1.00 0.00 N +ATOM 285 H LEU 32 -2.166 10.005 6.269 1.00 0.00 H +ATOM 286 CA LEU 32 -1.174 11.192 7.685 1.00 0.00 C +ATOM 287 CB LEU 32 -2.574 11.601 8.204 1.00 0.00 C +ATOM 288 CG LEU 32 -3.305 12.848 7.672 1.00 0.00 C +ATOM 289 CD1 LEU 32 -4.793 12.548 7.584 1.00 0.00 C +ATOM 290 CD2 LEU 32 -3.065 14.089 8.550 1.00 0.00 C +ATOM 291 C LEU 32 -0.331 10.624 8.826 1.00 0.00 C +ATOM 292 O LEU 32 0.560 11.324 9.319 1.00 0.00 O +ATOM 293 N HIS 33 -0.547 9.345 9.174 1.00 0.00 N +ATOM 294 H HIS 33 -1.247 8.812 8.720 1.00 0.00 H +ATOM 295 CA HIS 33 0.217 8.686 10.248 1.00 0.00 C +ATOM 296 CB HIS 33 -0.446 7.359 10.684 1.00 0.00 C +ATOM 297 CG HIS 33 -1.776 7.528 11.361 1.00 0.00 C +ATOM 298 CD2 HIS 33 -2.174 7.247 12.626 1.00 0.00 C +ATOM 299 ND1 HIS 33 -2.889 8.025 10.715 1.00 0.00 N +ATOM 300 HD1 HIS 33 -2.919 8.328 9.785 1.00 0.00 H +ATOM 301 CE1 HIS 33 -3.913 8.043 11.550 1.00 0.00 C +ATOM 302 NE2 HIS 33 -3.505 7.576 12.716 1.00 0.00 N +ATOM 303 HE2 HIS 33 -4.063 7.480 13.516 1.00 0.00 H +ATOM 304 C HIS 33 1.705 8.500 9.821 1.00 0.00 C +ATOM 305 O HIS 33 2.593 8.894 10.588 1.00 0.00 O +ATOM 306 N PRO 34 1.999 7.957 8.589 1.00 0.00 N +ATOM 307 CD PRO 34 1.213 7.038 7.743 1.00 0.00 C +ATOM 308 CA PRO 34 3.408 7.810 8.192 1.00 0.00 C +ATOM 309 CB PRO 34 3.329 6.952 6.933 1.00 0.00 C +ATOM 310 CG PRO 34 2.264 6.049 7.256 1.00 0.00 C +ATOM 311 C PRO 34 4.152 9.128 7.938 1.00 0.00 C +ATOM 312 O PRO 34 5.325 9.223 8.303 1.00 0.00 O +ATOM 313 N PHE 35 3.486 10.140 7.352 1.00 0.00 N +ATOM 314 H PHE 35 2.549 10.037 7.095 1.00 0.00 H +ATOM 315 CA PHE 35 4.151 11.431 7.100 1.00 0.00 C +ATOM 316 CB PHE 35 3.547 12.278 5.919 1.00 0.00 C +ATOM 317 CG PHE 35 2.219 13.021 6.191 1.00 0.00 C +ATOM 318 CD1 PHE 35 1.213 12.995 5.204 1.00 0.00 C +ATOM 319 CD2 PHE 35 2.009 13.847 7.329 1.00 0.00 C +ATOM 320 CE1 PHE 35 0.028 13.774 5.328 1.00 0.00 C +ATOM 321 CE2 PHE 35 0.830 14.630 7.469 1.00 0.00 C +ATOM 322 CZ PHE 35 -0.162 14.594 6.464 1.00 0.00 C +ATOM 323 C PHE 35 4.507 12.243 8.360 1.00 0.00 C +ATOM 324 O PHE 35 5.570 12.862 8.391 1.00 0.00 O +ATOM 325 N ASN 36 3.649 12.204 9.396 1.00 0.00 N +ATOM 326 H ASN 36 2.804 11.699 9.333 1.00 0.00 H +ATOM 327 CA ASN 36 3.916 12.922 10.660 1.00 0.00 C +ATOM 328 CB ASN 36 2.659 13.072 11.563 1.00 0.00 C +ATOM 329 CG ASN 36 2.025 11.736 11.996 1.00 0.00 C +ATOM 330 OD1 ASN 36 0.846 11.504 11.744 1.00 0.00 O +ATOM 331 ND2 ASN 36 2.775 10.910 12.726 1.00 0.00 N +ATOM 332 HD21 ASN 36 2.378 10.055 12.991 1.00 0.00 H +ATOM 333 HD22 ASN 36 3.680 11.180 12.981 1.00 0.00 H +ATOM 334 C ASN 36 5.109 12.319 11.428 1.00 0.00 C +ATOM 335 O ASN 36 5.981 13.062 11.895 1.00 0.00 O +ATOM 336 N THR 37 5.158 10.979 11.501 1.00 0.00 N +ATOM 337 H THR 37 4.434 10.435 11.094 1.00 0.00 H +ATOM 338 CA THR 37 6.248 10.250 12.182 1.00 0.00 C +ATOM 339 CB THR 37 5.877 8.745 12.493 1.00 0.00 C +ATOM 340 OG1 THR 37 6.956 8.109 13.191 1.00 0.00 O +ATOM 341 HG1 THR 37 7.745 8.092 12.642 1.00 0.00 H +ATOM 342 CG2 THR 37 5.547 7.948 11.228 1.00 0.00 C +ATOM 343 C THR 37 7.593 10.395 11.424 1.00 0.00 C +ATOM 344 O THR 37 8.646 10.530 12.057 1.00 0.00 O +ATOM 345 N PHE 38 7.529 10.371 10.082 1.00 0.00 N +ATOM 346 H PHE 38 6.662 10.236 9.639 1.00 0.00 H +ATOM 347 CA PHE 38 8.697 10.532 9.188 1.00 0.00 C +ATOM 348 CB PHE 38 8.362 10.085 7.744 1.00 0.00 C +ATOM 349 CG PHE 38 8.750 8.642 7.419 1.00 0.00 C +ATOM 350 CD1 PHE 38 7.848 7.575 7.645 1.00 0.00 C +ATOM 351 CD2 PHE 38 10.015 8.346 6.855 1.00 0.00 C +ATOM 352 CE1 PHE 38 8.197 6.236 7.317 1.00 0.00 C +ATOM 353 CE2 PHE 38 10.378 7.013 6.522 1.00 0.00 C +ATOM 354 CZ PHE 38 9.466 5.955 6.755 1.00 0.00 C +ATOM 355 C PHE 38 9.280 11.957 9.185 1.00 0.00 C +ATOM 356 O PHE 38 10.503 12.121 9.116 1.00 0.00 O +ATOM 357 N ARG 39 8.398 12.967 9.266 1.00 0.00 N +ATOM 358 H ARG 39 7.437 12.767 9.306 1.00 0.00 H +ATOM 359 CA ARG 39 8.765 14.402 9.304 1.00 0.00 C +ATOM 360 CB ARG 39 7.535 15.298 9.119 1.00 0.00 C +ATOM 361 CG ARG 39 7.120 15.497 7.668 1.00 0.00 C +ATOM 362 CD ARG 39 5.896 16.393 7.560 1.00 0.00 C +ATOM 363 NE ARG 39 5.482 16.595 6.170 1.00 0.00 N +ATOM 364 HE ARG 39 6.005 16.161 5.464 1.00 0.00 H +ATOM 365 CZ ARG 39 4.439 17.329 5.778 1.00 0.00 C +ATOM 366 NH1 ARG 39 4.165 17.436 4.485 1.00 0.00 N +ATOM 367 HH11 ARG 39 4.738 16.968 3.812 1.00 0.00 H +ATOM 368 HH12 ARG 39 3.385 17.984 4.183 1.00 0.00 H +ATOM 369 NH2 ARG 39 3.668 17.957 6.661 1.00 0.00 N +ATOM 370 HH21 ARG 39 3.865 17.884 7.638 1.00 0.00 H +ATOM 371 HH22 ARG 39 2.891 18.503 6.347 1.00 0.00 H +ATOM 372 C ARG 39 9.491 14.765 10.607 1.00 0.00 C +ATOM 373 O ARG 39 10.392 15.613 10.602 1.00 0.00 O +ATOM 374 N LYS 40 9.078 14.119 11.709 1.00 0.00 N +ATOM 375 H LYS 40 8.313 13.493 11.646 1.00 0.00 H +ATOM 376 CA LYS 40 9.658 14.296 13.058 1.00 0.00 C +ATOM 377 CB LYS 40 8.890 13.469 14.098 1.00 0.00 C +ATOM 378 CG LYS 40 7.543 14.053 14.501 1.00 0.00 C +ATOM 379 CD LYS 40 6.845 13.176 15.534 1.00 0.00 C +ATOM 380 CE LYS 40 5.490 13.743 15.952 1.00 0.00 C +ATOM 381 NZ LYS 40 5.590 15.006 16.743 1.00 0.00 N +ATOM 382 HZ1 LYS 40 4.635 15.335 16.993 1.00 0.00 H +ATOM 383 HZ2 LYS 40 6.134 14.829 17.612 1.00 0.00 H +ATOM 384 HZ3 LYS 40 6.070 15.734 16.176 1.00 0.00 H +ATOM 385 C LYS 40 11.153 13.930 13.102 1.00 0.00 C +ATOM 386 O LYS 40 11.924 14.566 13.829 1.00 0.00 O +ATOM 387 N GLU 41 11.538 12.912 12.316 1.00 0.00 N +ATOM 388 H GLU 41 10.876 12.444 11.760 1.00 0.00 H +ATOM 389 CA GLU 41 12.927 12.414 12.209 1.00 0.00 C +ATOM 390 CB GLU 41 12.941 10.923 11.844 1.00 0.00 C +ATOM 391 CG GLU 41 12.514 9.999 12.982 1.00 0.00 C +ATOM 392 CD GLU 41 12.463 8.541 12.571 1.00 0.00 C +ATOM 393 OE1 GLU 41 11.357 8.052 12.260 1.00 0.00 O +ATOM 394 OE2 GLU 41 13.524 7.880 12.567 1.00 0.00 O +ATOM 395 C GLU 41 13.790 13.211 11.215 1.00 0.00 C +ATOM 396 O GLU 41 14.961 13.484 11.499 1.00 0.00 O +ATOM 397 N GLY 42 13.207 13.571 10.066 1.00 0.00 N +ATOM 398 H GLY 42 12.277 13.324 9.867 1.00 0.00 H +ATOM 399 CA GLY 42 13.919 14.344 9.055 1.00 0.00 C +ATOM 400 C GLY 42 13.973 13.751 7.656 1.00 0.00 C +ATOM 401 O GLY 42 15.066 13.454 7.159 1.00 0.00 O +ATOM 402 N PHE 43 12.800 13.574 7.036 1.00 0.00 N +ATOM 403 H PHE 43 11.976 13.815 7.511 1.00 0.00 H +ATOM 404 CA PHE 43 12.658 13.033 5.671 1.00 0.00 C +ATOM 405 CB PHE 43 12.096 11.582 5.687 1.00 0.00 C +ATOM 406 CG PHE 43 12.948 10.570 6.454 1.00 0.00 C +ATOM 407 CD1 PHE 43 13.901 9.771 5.781 1.00 0.00 C +ATOM 408 CD2 PHE 43 12.769 10.377 7.845 1.00 0.00 C +ATOM 409 CE1 PHE 43 14.663 8.794 6.478 1.00 0.00 C +ATOM 410 CE2 PHE 43 13.524 9.403 8.555 1.00 0.00 C +ATOM 411 CZ PHE 43 14.473 8.610 7.869 1.00 0.00 C +ATOM 412 C PHE 43 11.706 13.944 4.880 1.00 0.00 C +ATOM 413 O PHE 43 10.815 14.564 5.473 1.00 0.00 O +ATOM 414 N GLU 44 11.901 14.015 3.555 1.00 0.00 N +ATOM 415 H GLU 44 12.625 13.501 3.133 1.00 0.00 H +ATOM 416 CA GLU 44 11.083 14.840 2.639 1.00 0.00 C +ATOM 417 CB GLU 44 11.976 15.543 1.603 1.00 0.00 C +ATOM 418 CG GLU 44 12.872 16.639 2.177 1.00 0.00 C +ATOM 419 CD GLU 44 13.731 17.308 1.121 1.00 0.00 C +ATOM 420 OE1 GLU 44 13.277 18.312 0.531 1.00 0.00 O +ATOM 421 OE2 GLU 44 14.861 16.833 0.881 1.00 0.00 O +ATOM 422 C GLU 44 9.995 14.002 1.937 1.00 0.00 C +ATOM 423 O GLU 44 10.280 12.899 1.454 1.00 0.00 O +ATOM 424 N VAL 45 8.761 14.529 1.904 1.00 0.00 N +ATOM 425 H VAL 45 8.589 15.413 2.295 1.00 0.00 H +ATOM 426 CA VAL 45 7.591 13.853 1.297 1.00 0.00 C +ATOM 427 CG1 VAL 45 6.752 12.575 3.334 1.00 0.00 C +ATOM 428 CG2 VAL 45 6.089 14.977 3.089 1.00 0.00 C +ATOM 429 C VAL 45 7.039 14.458 -0.015 1.00 0.00 C +ATOM 430 O VAL 45 6.912 15.685 -0.138 1.00 0.00 O +ATOM 431 CB VAL 45 6.407 13.665 2.334 1.00 0.00 C +ATOM 432 N ASP 46 6.759 13.577 -0.988 1.00 0.00 N +ATOM 433 H ASP 46 6.933 12.620 -0.850 1.00 0.00 H +ATOM 434 CA ASP 46 6.192 13.922 -2.308 1.00 0.00 C +ATOM 435 CB ASP 46 7.225 13.708 -3.434 1.00 0.00 C +ATOM 436 CG ASP 46 8.426 14.643 -3.325 1.00 0.00 C +ATOM 437 OD1 ASP 46 9.423 14.265 -2.670 1.00 0.00 O +ATOM 438 OD2 ASP 46 8.381 15.748 -3.908 1.00 0.00 O +ATOM 439 C ASP 46 4.973 13.011 -2.537 1.00 0.00 C +ATOM 440 O ASP 46 5.018 11.831 -2.165 1.00 0.00 O +ATOM 441 N PHE 47 3.893 13.557 -3.115 1.00 0.00 N +ATOM 442 H PHE 47 3.893 14.503 -3.380 1.00 0.00 H +ATOM 443 CA PHE 47 2.658 12.791 -3.386 1.00 0.00 C +ATOM 444 CB PHE 47 1.449 13.419 -2.639 1.00 0.00 C +ATOM 445 CG PHE 47 1.575 13.439 -1.117 1.00 0.00 C +ATOM 446 CD1 PHE 47 2.173 14.539 -0.454 1.00 0.00 C +ATOM 447 CD2 PHE 47 1.059 12.379 -0.333 1.00 0.00 C +ATOM 448 CE1 PHE 47 2.257 14.585 0.964 1.00 0.00 C +ATOM 449 CE2 PHE 47 1.136 12.411 1.087 1.00 0.00 C +ATOM 450 CZ PHE 47 1.737 13.517 1.736 1.00 0.00 C +ATOM 451 C PHE 47 2.325 12.681 -4.882 1.00 0.00 C +ATOM 452 O PHE 47 2.258 13.699 -5.584 1.00 0.00 O +ATOM 453 N VAL 48 2.171 11.438 -5.364 1.00 0.00 N +ATOM 454 H VAL 48 2.287 10.661 -4.776 1.00 0.00 H +ATOM 455 CA VAL 48 1.824 11.127 -6.767 1.00 0.00 C +ATOM 456 CB VAL 48 3.099 10.734 -7.641 1.00 0.00 C +ATOM 457 CG1 VAL 48 3.780 9.446 -7.133 1.00 0.00 C +ATOM 458 CG2 VAL 48 2.747 10.651 -9.127 1.00 0.00 C +ATOM 459 C VAL 48 0.675 10.097 -6.917 1.00 0.00 C +ATOM 460 O VAL 48 0.592 9.145 -6.138 1.00 0.00 O +ATOM 461 N SER 49 -0.171 10.301 -7.937 1.00 0.00 N +ATOM 462 H SER 49 -0.056 11.076 -8.523 1.00 0.00 H +ATOM 463 CA SER 49 -1.299 9.415 -8.281 1.00 0.00 C +ATOM 464 CB SER 49 -2.586 10.225 -8.467 1.00 0.00 C +ATOM 465 OG SER 49 -3.715 9.383 -8.646 1.00 0.00 O +ATOM 466 HG SER 49 -3.624 8.863 -9.449 1.00 0.00 H +ATOM 467 C SER 49 -0.912 8.733 -9.604 1.00 0.00 C +ATOM 468 O SER 49 -0.155 9.320 -10.385 1.00 0.00 O +ATOM 469 N GLU 50 -1.455 7.532 -9.861 1.00 0.00 N +ATOM 470 H GLU 50 -2.081 7.149 -9.207 1.00 0.00 H +ATOM 471 CA GLU 50 -1.182 6.719 -11.072 1.00 0.00 C +ATOM 472 CB GLU 50 -2.067 5.455 -11.065 1.00 0.00 C +ATOM 473 CG GLU 50 -1.513 4.199 -11.801 1.00 0.00 C +ATOM 474 CD GLU 50 -1.966 4.087 -13.258 1.00 0.00 C +ATOM 475 OE1 GLU 50 -2.903 3.309 -13.533 1.00 0.00 O +ATOM 476 OE2 GLU 50 -1.379 4.773 -14.122 1.00 0.00 O +ATOM 477 C GLU 50 -1.370 7.486 -12.401 1.00 0.00 C +ATOM 478 O GLU 50 -0.618 7.265 -13.358 1.00 0.00 O +ATOM 479 N THR 51 -2.372 8.375 -12.429 1.00 0.00 N +ATOM 480 H THR 51 -2.943 8.503 -11.639 1.00 0.00 H +ATOM 481 CA THR 51 -2.709 9.216 -13.591 1.00 0.00 C +ATOM 482 CB THR 51 -4.175 8.976 -14.060 1.00 0.00 C +ATOM 483 OG1 THR 51 -5.051 8.972 -12.926 1.00 0.00 O +ATOM 484 HG1 THR 51 -4.841 8.243 -12.337 1.00 0.00 H +ATOM 485 CG2 THR 51 -4.293 7.648 -14.798 1.00 0.00 C +ATOM 486 C THR 51 -2.506 10.695 -13.226 1.00 0.00 C +ATOM 487 O THR 51 -2.526 11.044 -12.040 1.00 0.00 O +ATOM 488 N GLY 52 -2.312 11.548 -14.241 1.00 0.00 N +ATOM 489 H GLY 52 -2.312 11.232 -15.171 1.00 0.00 H +ATOM 490 CA GLY 52 -2.094 12.978 -14.036 1.00 0.00 C +ATOM 491 C GLY 52 -3.339 13.833 -13.821 1.00 0.00 C +ATOM 492 O GLY 52 -3.325 15.028 -14.140 1.00 0.00 O +ATOM 493 N LYS 53 -4.401 13.216 -13.286 1.00 0.00 N +ATOM 494 H LYS 53 -4.343 12.263 -13.072 1.00 0.00 H +ATOM 495 CA LYS 53 -5.682 13.886 -12.990 1.00 0.00 C +ATOM 496 CB LYS 53 -6.890 13.074 -13.517 1.00 0.00 C +ATOM 497 CG LYS 53 -6.940 11.570 -13.174 1.00 0.00 C +ATOM 498 CD LYS 53 -8.183 10.915 -13.754 1.00 0.00 C +ATOM 499 CE LYS 53 -8.238 9.435 -13.412 1.00 0.00 C +ATOM 500 NZ LYS 53 -9.452 8.780 -13.973 1.00 0.00 N +ATOM 501 HZ1 LYS 53 -9.451 7.772 -13.718 1.00 0.00 H +ATOM 502 HZ2 LYS 53 -10.302 9.236 -13.586 1.00 0.00 H +ATOM 503 HZ3 LYS 53 -9.449 8.875 -15.009 1.00 0.00 H +ATOM 504 C LYS 53 -5.836 14.198 -11.490 1.00 0.00 C +ATOM 505 O LYS 53 -6.251 15.304 -11.124 1.00 0.00 O +ATOM 506 N PHE 54 -5.485 13.210 -10.646 1.00 0.00 N +ATOM 507 H PHE 54 -5.168 12.354 -11.010 1.00 0.00 H +ATOM 508 CA PHE 54 -5.522 13.258 -9.160 1.00 0.00 C +ATOM 509 CB PHE 54 -4.443 14.227 -8.602 1.00 0.00 C +ATOM 510 CG PHE 54 -2.998 13.840 -8.928 1.00 0.00 C +ATOM 511 CD1 PHE 54 -2.061 13.693 -7.888 1.00 0.00 C +ATOM 512 CD2 PHE 54 -2.544 13.691 -10.262 1.00 0.00 C +ATOM 513 CE1 PHE 54 -0.702 13.408 -8.156 1.00 0.00 C +ATOM 514 CE2 PHE 54 -1.187 13.404 -10.544 1.00 0.00 C +ATOM 515 CZ PHE 54 -0.262 13.263 -9.488 1.00 0.00 C +ATOM 516 C PHE 54 -6.888 13.562 -8.523 1.00 0.00 C +ATOM 517 O PHE 54 -7.590 14.487 -8.951 1.00 0.00 O +ATOM 518 N GLY 55 -7.250 12.767 -7.513 1.00 0.00 N +ATOM 519 H GLY 55 -6.672 12.035 -7.204 1.00 0.00 H +ATOM 520 CA GLY 55 -8.516 12.937 -6.813 1.00 0.00 C +ATOM 521 C GLY 55 -8.900 11.713 -6.005 1.00 0.00 C +ATOM 522 O GLY 55 -9.127 10.648 -6.588 1.00 0.00 O +ATOM 523 N TRP 56 -8.985 11.867 -4.676 1.00 0.00 N +ATOM 524 H TRP 56 -8.794 12.749 -4.290 1.00 0.00 H +ATOM 525 CA TRP 56 -9.353 10.782 -3.747 1.00 0.00 C +ATOM 526 CB TRP 56 -8.900 11.102 -2.302 1.00 0.00 C +ATOM 527 CG TRP 56 -7.391 11.085 -1.963 1.00 0.00 C +ATOM 528 CD2 TRP 56 -6.655 12.104 -1.255 1.00 0.00 C +ATOM 529 CE2 TRP 56 -5.330 11.616 -1.070 1.00 0.00 C +ATOM 530 CE3 TRP 56 -6.983 13.385 -0.755 1.00 0.00 C +ATOM 531 CD1 TRP 56 -6.495 10.055 -2.171 1.00 0.00 C +ATOM 532 NE1 TRP 56 -5.270 10.371 -1.638 1.00 0.00 N +ATOM 533 HE1 TRP 56 -4.481 9.791 -1.669 1.00 0.00 H +ATOM 534 CZ2 TRP 56 -4.328 12.364 -0.406 1.00 0.00 C +ATOM 535 CZ3 TRP 56 -5.981 14.135 -0.090 1.00 0.00 C +ATOM 536 CH2 TRP 56 -4.669 13.614 0.074 1.00 0.00 C +ATOM 537 C TRP 56 -10.871 10.490 -3.752 1.00 0.00 C +ATOM 538 O TRP 56 -11.313 9.532 -4.399 1.00 0.00 O +ATOM 539 N ASP 57 -11.644 11.319 -3.032 1.00 0.00 N +ATOM 540 H ASP 57 -11.242 12.070 -2.543 1.00 0.00 H +ATOM 541 CA ASP 57 -13.110 11.219 -2.899 1.00 0.00 C +ATOM 542 CB ASP 57 -13.486 10.362 -1.670 1.00 0.00 C +ATOM 543 CG ASP 57 -14.903 9.789 -1.750 1.00 0.00 C +ATOM 544 OD1 ASP 57 -15.852 10.478 -1.317 1.00 0.00 O +ATOM 545 OD2 ASP 57 -15.062 8.649 -2.237 1.00 0.00 O +ATOM 546 C ASP 57 -13.657 12.645 -2.716 1.00 0.00 C +ATOM 547 O ASP 57 -14.820 12.915 -3.042 1.00 0.00 O +ATOM 548 N GLU 58 -12.797 13.537 -2.189 1.00 0.00 N +ATOM 549 H GLU 58 -11.885 13.250 -1.966 1.00 0.00 H +ATOM 550 CA GLU 58 -13.061 14.973 -1.901 1.00 0.00 C +ATOM 551 CB GLU 58 -13.438 15.763 -3.170 1.00 0.00 C +ATOM 552 CG GLU 58 -12.346 15.834 -4.235 1.00 0.00 C +ATOM 553 CD GLU 58 -12.772 16.620 -5.461 1.00 0.00 C +ATOM 554 OE1 GLU 58 -12.553 17.850 -5.486 1.00 0.00 O +ATOM 555 OE2 GLU 58 -13.324 16.009 -6.400 1.00 0.00 O +ATOM 556 C GLU 58 -14.066 15.257 -0.766 1.00 0.00 C +ATOM 557 O GLU 58 -15.201 14.762 -0.793 1.00 0.00 O +ATOM 558 N HIS 59 -13.612 16.034 0.235 1.00 0.00 N +ATOM 559 H HIS 59 -12.689 16.370 0.201 1.00 0.00 H +ATOM 560 CA HIS 59 -14.362 16.472 1.447 1.00 0.00 C +ATOM 561 CB HIS 59 -15.335 17.634 1.101 1.00 0.00 C +ATOM 562 CG HIS 59 -15.510 18.649 2.197 1.00 0.00 C +ATOM 563 CD2 HIS 59 -15.140 19.950 2.276 1.00 0.00 C +ATOM 564 ND1 HIS 59 -16.153 18.364 3.384 1.00 0.00 N +ATOM 565 HD1 HIS 59 -16.542 17.500 3.632 1.00 0.00 H +ATOM 566 CE1 HIS 59 -16.172 19.444 4.145 1.00 0.00 C +ATOM 567 NE2 HIS 59 -15.564 20.420 3.496 1.00 0.00 N +ATOM 568 HE2 HIS 59 -15.436 21.332 3.830 1.00 0.00 H +ATOM 569 C HIS 59 -15.069 15.355 2.266 1.00 0.00 C +ATOM 570 O HIS 59 -15.924 15.644 3.118 1.00 0.00 O +ATOM 571 N SER 60 -14.668 14.094 2.023 1.00 0.00 N +ATOM 572 H SER 60 -13.972 13.935 1.349 1.00 0.00 H +ATOM 573 CA SER 60 -15.182 12.859 2.679 1.00 0.00 C +ATOM 574 CB SER 60 -14.800 12.817 4.178 1.00 0.00 C +ATOM 575 OG SER 60 -15.190 11.599 4.793 1.00 0.00 O +ATOM 576 HG SER 60 -16.145 11.501 4.763 1.00 0.00 H +ATOM 577 C SER 60 -16.687 12.555 2.484 1.00 0.00 C +ATOM 578 O SER 60 -17.453 13.435 2.073 1.00 0.00 O +ATOM 579 N LEU 61 -17.079 11.307 2.782 1.00 0.00 N +ATOM 580 H LEU 61 -16.425 10.648 3.104 1.00 0.00 H +ATOM 581 CA LEU 61 -18.463 10.813 2.664 1.00 0.00 C +ATOM 582 CB LEU 61 -18.470 9.361 2.138 1.00 0.00 C +ATOM 583 CG LEU 61 -18.070 9.030 0.689 1.00 0.00 C +ATOM 584 CD1 LEU 61 -16.921 8.024 0.679 1.00 0.00 C +ATOM 585 CD2 LEU 61 -19.265 8.478 -0.095 1.00 0.00 C +ATOM 586 C LEU 61 -19.235 10.897 3.996 1.00 0.00 C +ATOM 587 O LEU 61 -18.729 10.461 5.039 1.00 0.00 O +ATOM 588 N ALA 62 -20.433 11.500 3.946 1.00 0.00 N +ATOM 589 H ALA 62 -20.772 11.859 3.097 1.00 0.00 H +ATOM 590 CA ALA 62 -21.325 11.678 5.109 1.00 0.00 C +ATOM 591 CB ALA 62 -21.227 13.115 5.649 1.00 0.00 C +ATOM 592 C ALA 62 -22.776 11.363 4.724 1.00 0.00 C +ATOM 593 O ALA 62 -23.576 10.973 5.583 1.00 0.00 O +ATOM 594 N LYS 63 -23.094 11.529 3.428 1.00 0.00 N +ATOM 595 H LYS 63 -22.403 11.832 2.797 1.00 0.00 H +ATOM 596 CA LYS 63 -24.426 11.300 2.801 1.00 0.00 C +ATOM 597 CB LYS 63 -24.705 9.795 2.571 1.00 0.00 C +ATOM 598 CG LYS 63 -23.812 9.132 1.528 1.00 0.00 C +ATOM 599 CD LYS 63 -24.166 7.659 1.354 1.00 0.00 C +ATOM 600 CE LYS 63 -23.281 6.972 0.316 1.00 0.00 C +ATOM 601 NZ LYS 63 -21.861 6.818 0.751 1.00 0.00 N +ATOM 602 HZ1 LYS 63 -21.452 7.755 0.938 1.00 0.00 H +ATOM 603 HZ2 LYS 63 -21.825 6.245 1.619 1.00 0.00 H +ATOM 604 HZ3 LYS 63 -21.318 6.345 0.001 1.00 0.00 H +ATOM 605 C LYS 63 -25.634 12.017 3.459 1.00 0.00 C +ATOM 606 O LYS 63 -25.809 13.223 3.245 1.00 0.00 O +ATOM 607 N ASP 64 -26.446 11.286 4.241 1.00 0.00 N +ATOM 608 H ASP 64 -26.274 10.335 4.406 1.00 0.00 H +ATOM 609 CA ASP 64 -27.636 11.825 4.931 1.00 0.00 C +ATOM 610 CB ASP 64 -28.939 11.344 4.256 1.00 0.00 C +ATOM 611 CG ASP 64 -29.119 11.901 2.847 1.00 0.00 C +ATOM 612 OD1 ASP 64 -29.731 12.982 2.702 1.00 0.00 O +ATOM 613 OD2 ASP 64 -28.665 11.248 1.881 1.00 0.00 O +ATOM 614 C ASP 64 -27.657 11.433 6.417 1.00 0.00 C +ATOM 615 O ASP 64 -27.960 12.275 7.271 1.00 0.00 O +ATOM 616 N PHE 65 -27.334 10.164 6.706 1.00 0.00 N +ATOM 617 H PHE 65 -27.093 9.538 5.987 1.00 0.00 H +ATOM 618 CA PHE 65 -27.307 9.605 8.071 1.00 0.00 C +ATOM 619 CB PHE 65 -28.128 8.288 8.131 1.00 0.00 C +ATOM 620 CG PHE 65 -29.622 8.451 7.849 1.00 0.00 C +ATOM 621 CD1 PHE 65 -30.537 8.690 8.903 1.00 0.00 C +ATOM 622 CD2 PHE 65 -30.128 8.326 6.533 1.00 0.00 C +ATOM 623 CE1 PHE 65 -31.933 8.803 8.653 1.00 0.00 C +ATOM 624 CE2 PHE 65 -31.521 8.438 6.267 1.00 0.00 C +ATOM 625 CZ PHE 65 -32.425 8.677 7.331 1.00 0.00 C +ATOM 626 C PHE 65 -25.873 9.348 8.561 1.00 0.00 C +ATOM 627 O PHE 65 -24.953 9.234 7.742 1.00 0.00 O +ATOM 628 N LEU 66 -25.700 9.280 9.890 1.00 0.00 N +ATOM 629 H LEU 66 -26.465 9.395 10.496 1.00 0.00 H +ATOM 630 CA LEU 66 -24.402 9.037 10.547 1.00 0.00 C +ATOM 631 CB LEU 66 -24.065 10.201 11.512 1.00 0.00 C +ATOM 632 CG LEU 66 -22.625 10.680 11.809 1.00 0.00 C +ATOM 633 CD1 LEU 66 -22.627 12.192 11.957 1.00 0.00 C +ATOM 634 CD2 LEU 66 -22.033 10.016 13.063 1.00 0.00 C +ATOM 635 C LEU 66 -24.452 7.697 11.312 1.00 0.00 C +ATOM 636 O LEU 66 -23.448 6.976 11.362 1.00 0.00 O +ATOM 637 N ASN 67 -25.621 7.388 11.895 1.00 0.00 N +ATOM 638 H ASN 67 -26.387 7.998 11.820 1.00 0.00 H +ATOM 639 CA ASN 67 -25.861 6.157 12.672 1.00 0.00 C +ATOM 640 CB ASN 67 -26.415 6.514 14.068 1.00 0.00 C +ATOM 641 CG ASN 67 -26.076 5.468 15.133 1.00 0.00 C +ATOM 642 OD1 ASN 67 -25.046 5.560 15.805 1.00 0.00 O +ATOM 643 ND2 ASN 67 -26.953 4.482 15.298 1.00 0.00 N +ATOM 644 HD21 ASN 67 -26.751 3.804 15.976 1.00 0.00 H +ATOM 645 HD22 ASN 67 -27.762 4.463 14.744 1.00 0.00 H +ATOM 646 C ASN 67 -26.848 5.243 11.920 1.00 0.00 C +ATOM 647 O ASN 67 -27.641 5.725 11.104 1.00 0.00 O +ATOM 648 N GLY 68 -26.782 3.939 12.209 1.00 0.00 N +ATOM 649 H GLY 68 -26.137 3.595 12.864 1.00 0.00 H +ATOM 650 CA GLY 68 -27.656 2.959 11.575 1.00 0.00 C +ATOM 651 C GLY 68 -27.509 1.568 12.170 1.00 0.00 C +ATOM 652 O GLY 68 -26.584 1.327 12.956 1.00 0.00 O +ATOM 653 N GLN 69 -28.422 0.665 11.790 1.00 0.00 N +ATOM 654 H GLN 69 -29.122 0.937 11.159 1.00 0.00 H +ATOM 655 CA GLN 69 -28.451 -0.732 12.262 1.00 0.00 C +ATOM 656 CB GLN 69 -29.801 -1.053 12.928 1.00 0.00 C +ATOM 657 CG GLN 69 -30.044 -0.343 14.256 1.00 0.00 C +ATOM 658 CD GLN 69 -31.386 -0.695 14.868 1.00 0.00 C +ATOM 659 OE1 GLN 69 -31.496 -1.640 15.649 1.00 0.00 O +ATOM 660 NE2 GLN 69 -32.417 0.066 14.515 1.00 0.00 N +ATOM 661 HE21 GLN 69 -32.276 0.808 13.889 1.00 0.00 H +ATOM 662 HE22 GLN 69 -33.291 -0.149 14.903 1.00 0.00 H +ATOM 663 C GLN 69 -28.184 -1.737 11.130 1.00 0.00 C +ATOM 664 O GLN 69 -28.451 -1.435 9.962 1.00 0.00 O +ATOM 665 N ASP 70 -27.676 -2.927 11.506 1.00 0.00 N +ATOM 666 H ASP 70 -27.501 -3.090 12.459 1.00 0.00 H +ATOM 667 CA ASP 70 -27.324 -4.087 10.635 1.00 0.00 C +ATOM 668 CB ASP 70 -28.411 -5.198 10.702 1.00 0.00 C +ATOM 669 CG ASP 70 -29.821 -4.695 10.368 1.00 0.00 C +ATOM 670 OD1 ASP 70 -30.543 -4.275 11.299 1.00 0.00 O +ATOM 671 OD2 ASP 70 -30.206 -4.735 9.179 1.00 0.00 O +ATOM 672 C ASP 70 -26.828 -3.885 9.180 1.00 0.00 C +ATOM 673 O ASP 70 -25.699 -4.273 8.858 1.00 0.00 O +ATOM 674 N GLU 71 -27.675 -3.284 8.329 1.00 0.00 N +ATOM 675 H GLU 71 -28.555 -2.998 8.659 1.00 0.00 H +ATOM 676 CA GLU 71 -27.389 -3.006 6.905 1.00 0.00 C +ATOM 677 CB GLU 71 -28.666 -2.577 6.168 1.00 0.00 C +ATOM 678 CG GLU 71 -29.707 -3.681 5.995 1.00 0.00 C +ATOM 679 CD GLU 71 -30.947 -3.208 5.259 1.00 0.00 C +ATOM 680 OE1 GLU 71 -30.975 -3.307 4.014 1.00 0.00 O +ATOM 681 OE2 GLU 71 -31.894 -2.739 5.925 1.00 0.00 O +ATOM 682 C GLU 71 -26.294 -1.950 6.702 1.00 0.00 C +ATOM 683 O GLU 71 -25.455 -2.091 5.805 1.00 0.00 O +ATOM 684 N THR 72 -26.292 -0.936 7.581 1.00 0.00 N +ATOM 685 H THR 72 -26.982 -0.940 8.285 1.00 0.00 H +ATOM 686 CA THR 72 -25.336 0.192 7.590 1.00 0.00 C +ATOM 687 CB THR 72 -25.716 1.241 8.684 1.00 0.00 C +ATOM 688 OG1 THR 72 -27.129 1.196 8.917 1.00 0.00 O +ATOM 689 HG1 THR 72 -27.611 1.453 8.126 1.00 0.00 H +ATOM 690 CG2 THR 72 -25.350 2.663 8.236 1.00 0.00 C +ATOM 691 C THR 72 -23.890 -0.313 7.806 1.00 0.00 C +ATOM 692 O THR 72 -22.943 0.243 7.233 1.00 0.00 O +ATOM 693 N ASP 73 -23.752 -1.377 8.613 1.00 0.00 N +ATOM 694 H ASP 73 -24.553 -1.779 9.019 1.00 0.00 H +ATOM 695 CA ASP 73 -22.461 -2.010 8.944 1.00 0.00 C +ATOM 696 CG ASP 73 -21.395 -3.188 10.960 1.00 0.00 C +ATOM 697 OD1 ASP 73 -21.253 -2.449 11.959 1.00 0.00 O +ATOM 698 OD2 ASP 73 -20.564 -4.069 10.648 1.00 0.00 O +ATOM 699 C ASP 73 -21.820 -2.694 7.713 1.00 0.00 C +ATOM 700 O ASP 73 -20.621 -2.510 7.473 1.00 0.00 O +ATOM 701 CB ASP 73 -22.648 -3.021 10.095 1.00 0.00 C +ATOM 702 N PHE 74 -22.613 -3.470 6.954 1.00 0.00 N +ATOM 703 H PHE 74 -23.557 -3.599 7.194 1.00 0.00 H +ATOM 704 CA PHE 74 -22.135 -4.164 5.741 1.00 0.00 C +ATOM 705 CB PHE 74 -23.037 -5.381 5.355 1.00 0.00 C +ATOM 706 CG PHE 74 -24.578 -5.045 5.082 1.00 0.00 C +ATOM 707 CD1 PHE 74 -25.291 -4.606 3.940 1.00 0.00 C +ATOM 708 CD2 PHE 74 -25.750 -5.843 5.102 1.00 0.00 C +ATOM 709 CE1 PHE 74 -25.992 -5.661 4.688 1.00 0.00 C +ATOM 710 CE2 PHE 74 -25.696 -4.903 3.994 1.00 0.00 C +ATOM 711 CZ PHE 74 -24.845 -5.102 4.966 1.00 0.00 C +ATOM 712 C PHE 74 -21.827 -3.278 4.515 1.00 0.00 C +ATOM 713 O PHE 74 -20.783 -3.457 3.878 1.00 0.00 O +ATOM 714 N LYS 75 -22.734 -2.339 4.199 1.00 0.00 N +ATOM 715 H LYS 75 -23.552 -2.240 4.738 1.00 0.00 H +ATOM 716 CA LYS 75 -22.587 -1.408 3.055 1.00 0.00 C +ATOM 717 CB LYS 75 -23.936 -0.754 2.673 1.00 0.00 C +ATOM 718 CG LYS 75 -24.651 0.097 3.740 1.00 0.00 C +ATOM 719 CD LYS 75 -25.941 0.695 3.186 1.00 0.00 C +ATOM 720 CE LYS 75 -26.657 1.581 4.203 1.00 0.00 C +ATOM 721 NZ LYS 75 -25.924 2.846 4.513 1.00 0.00 N +ATOM 722 HZ1 LYS 75 -25.809 3.402 3.642 1.00 0.00 H +ATOM 723 HZ2 LYS 75 -26.465 3.398 5.208 1.00 0.00 H +ATOM 724 HZ3 LYS 75 -24.988 2.617 4.904 1.00 0.00 H +ATOM 725 C LYS 75 -21.468 -0.350 3.190 1.00 0.00 C +ATOM 726 O LYS 75 -20.802 -0.025 2.202 1.00 0.00 O +ATOM 727 N ASN 76 -21.282 0.165 4.419 1.00 0.00 N +ATOM 728 H ASN 76 -21.848 -0.146 5.160 1.00 0.00 H +ATOM 729 CA ASN 76 -20.277 1.193 4.809 1.00 0.00 C +ATOM 730 CB ASN 76 -18.845 0.606 4.865 1.00 0.00 C +ATOM 731 CG ASN 76 -18.691 -0.480 5.923 1.00 0.00 C +ATOM 732 OD1 ASN 76 -18.360 -0.200 7.077 1.00 0.00 O +ATOM 733 ND2 ASN 76 -18.912 -1.731 5.526 1.00 0.00 N +ATOM 734 HD21 ASN 76 -18.816 -2.442 6.193 1.00 0.00 H +ATOM 735 HD22 ASN 76 -19.160 -1.901 4.592 1.00 0.00 H +ATOM 736 C ASN 76 -20.296 2.505 3.990 1.00 0.00 C +ATOM 737 O ASN 76 -20.168 2.474 2.759 1.00 0.00 O +ATOM 738 N LYS 77 -20.490 3.635 4.685 1.00 0.00 N +ATOM 739 H LYS 77 -20.608 3.606 5.660 1.00 0.00 H +ATOM 740 CA LYS 77 -20.543 4.977 4.071 1.00 0.00 C +ATOM 741 CB LYS 77 -21.949 5.618 4.224 1.00 0.00 C +ATOM 742 CG LYS 77 -22.618 5.512 5.609 1.00 0.00 C +ATOM 743 CD LYS 77 -23.955 6.242 5.638 1.00 0.00 C +ATOM 744 CE LYS 77 -24.664 6.095 6.983 1.00 0.00 C +ATOM 745 NZ LYS 77 -23.948 6.752 8.118 1.00 0.00 N +ATOM 746 HZ1 LYS 77 -23.005 6.325 8.224 1.00 0.00 H +ATOM 747 HZ2 LYS 77 -23.846 7.768 7.925 1.00 0.00 H +ATOM 748 HZ3 LYS 77 -24.490 6.616 8.995 1.00 0.00 H +ATOM 749 C LYS 77 -19.433 5.945 4.537 1.00 0.00 C +ATOM 750 O LYS 77 -18.653 6.427 3.708 1.00 0.00 O +ATOM 751 N ASP 78 -19.377 6.214 5.851 1.00 0.00 N +ATOM 752 H ASP 78 -20.017 5.796 6.468 1.00 0.00 H +ATOM 753 CA ASP 78 -18.390 7.123 6.465 1.00 0.00 C +ATOM 754 CB ASP 78 -19.091 8.202 7.331 1.00 0.00 C +ATOM 755 CG ASP 78 -20.140 7.627 8.293 1.00 0.00 C +ATOM 756 OD1 ASP 78 -19.779 7.291 9.443 1.00 0.00 O +ATOM 757 OD2 ASP 78 -21.323 7.526 7.900 1.00 0.00 O +ATOM 758 C ASP 78 -17.278 6.412 7.263 1.00 0.00 C +ATOM 759 O ASP 78 -17.565 5.516 8.068 1.00 0.00 O +ATOM 760 N SER 79 -16.022 6.809 7.007 1.00 0.00 N +ATOM 761 H SER 79 -15.849 7.510 6.342 1.00 0.00 H +ATOM 762 CA SER 79 -14.828 6.255 7.673 1.00 0.00 C +ATOM 763 CB SER 79 -13.987 5.419 6.685 1.00 0.00 C +ATOM 764 OG SER 79 -13.642 6.167 5.530 1.00 0.00 O +ATOM 765 HG SER 79 -14.431 6.420 5.045 1.00 0.00 H +ATOM 766 C SER 79 -13.972 7.357 8.330 1.00 0.00 C +ATOM 767 O SER 79 -13.950 7.463 9.562 1.00 0.00 O +ATOM 768 N ASP 80 -13.281 8.162 7.505 1.00 0.00 N +ATOM 769 H ASP 80 -13.342 8.032 6.533 1.00 0.00 H +ATOM 770 CA ASP 80 -12.399 9.271 7.939 1.00 0.00 C +ATOM 771 CB ASP 80 -10.941 8.775 8.162 1.00 0.00 C +ATOM 772 CG ASP 80 -10.446 7.828 7.062 1.00 0.00 C +ATOM 773 OD1 ASP 80 -9.838 8.314 6.084 1.00 0.00 O +ATOM 774 OD2 ASP 80 -10.653 6.601 7.188 1.00 0.00 O +ATOM 775 C ASP 80 -12.443 10.449 6.938 1.00 0.00 C +ATOM 776 O ASP 80 -13.166 10.373 5.939 1.00 0.00 O +ATOM 777 N PHE 81 -11.660 11.508 7.205 1.00 0.00 N +ATOM 778 H PHE 81 -11.096 11.495 8.010 1.00 0.00 H +ATOM 779 CA PHE 81 -11.568 12.725 6.365 1.00 0.00 C +ATOM 780 CB PHE 81 -10.910 13.881 7.159 1.00 0.00 C +ATOM 781 CG PHE 81 -11.704 14.358 8.375 1.00 0.00 C +ATOM 782 CD1 PHE 81 -11.485 13.787 9.653 1.00 0.00 C +ATOM 783 CD2 PHE 81 -12.647 15.407 8.259 1.00 0.00 C +ATOM 784 CE1 PHE 81 -12.192 14.252 10.796 1.00 0.00 C +ATOM 785 CE2 PHE 81 -13.362 15.882 9.393 1.00 0.00 C +ATOM 786 CZ PHE 81 -13.133 15.303 10.665 1.00 0.00 C +ATOM 787 C PHE 81 -10.788 12.495 5.057 1.00 0.00 C +ATOM 788 O PHE 81 -9.928 11.610 5.006 1.00 0.00 O +ATOM 789 N ASN 82 -11.095 13.294 4.023 1.00 0.00 N +ATOM 790 H ASN 82 -11.783 13.988 4.121 1.00 0.00 H +ATOM 791 CA ASN 82 -10.453 13.206 2.698 1.00 0.00 C +ATOM 792 CB ASN 82 -11.516 13.251 1.583 1.00 0.00 C +ATOM 793 CG ASN 82 -11.001 12.726 0.244 1.00 0.00 C +ATOM 794 OD1 ASN 82 -10.406 13.466 -0.543 1.00 0.00 O +ATOM 795 ND2 ASN 82 -11.239 11.452 -0.019 1.00 0.00 N +ATOM 796 HD21 ASN 82 -11.710 10.909 0.649 1.00 0.00 H +ATOM 797 HD22 ASN 82 -10.949 11.092 -0.878 1.00 0.00 H +ATOM 798 C ASN 82 -9.401 14.308 2.471 1.00 0.00 C +ATOM 799 O ASN 82 -8.282 14.006 2.040 1.00 0.00 O +ATOM 800 N LYS 83 -9.782 15.571 2.741 1.00 0.00 N +ATOM 801 H LYS 83 -10.692 15.740 3.069 1.00 0.00 H +ATOM 802 CA LYS 83 -8.942 16.791 2.592 1.00 0.00 C +ATOM 803 CB LYS 83 -7.690 16.729 3.495 1.00 0.00 C +ATOM 804 CG LYS 83 -7.978 16.793 4.991 1.00 0.00 C +ATOM 805 CD LYS 83 -6.691 16.723 5.807 1.00 0.00 C +ATOM 806 CE LYS 83 -6.957 16.782 7.309 1.00 0.00 C +ATOM 807 NZ LYS 83 -7.641 15.567 7.844 1.00 0.00 N +ATOM 808 HZ1 LYS 83 -7.051 14.729 7.665 1.00 0.00 H +ATOM 809 HZ2 LYS 83 -7.789 15.674 8.868 1.00 0.00 H +ATOM 810 HZ3 LYS 83 -8.560 15.450 7.371 1.00 0.00 H +ATOM 811 C LYS 83 -8.557 17.138 1.131 1.00 0.00 C +ATOM 812 O LYS 83 -7.670 17.972 0.894 1.00 0.00 O +ATOM 813 N THR 84 -9.300 16.552 0.173 1.00 0.00 N +ATOM 814 H THR 84 -10.037 15.958 0.439 1.00 0.00 H +ATOM 815 CA THR 84 -9.149 16.688 -1.309 1.00 0.00 C +ATOM 816 CB THR 84 -9.998 17.894 -1.929 1.00 0.00 C +ATOM 817 OG1 THR 84 -9.873 17.899 -3.357 1.00 0.00 O +ATOM 818 HG1 THR 84 -10.384 18.625 -3.721 1.00 0.00 H +ATOM 819 CG2 THR 84 -9.575 19.269 -1.370 1.00 0.00 C +ATOM 820 C THR 84 -7.724 16.605 -1.918 1.00 0.00 C +ATOM 821 O THR 84 -6.781 17.216 -1.398 1.00 0.00 O +ATOM 822 N LEU 85 -7.602 15.855 -3.022 1.00 0.00 N +ATOM 823 H LEU 85 -8.389 15.412 -3.410 1.00 0.00 H +ATOM 824 CA LEU 85 -6.334 15.628 -3.735 1.00 0.00 C +ATOM 825 CB LEU 85 -6.298 14.185 -4.299 1.00 0.00 C +ATOM 826 CG LEU 85 -5.057 13.264 -4.326 1.00 0.00 C +ATOM 827 CD1 LEU 85 -5.439 11.962 -5.004 1.00 0.00 C +ATOM 828 CD2 LEU 85 -3.833 13.861 -5.008 1.00 0.00 C +ATOM 829 C LEU 85 -6.040 16.649 -4.862 1.00 0.00 C +ATOM 830 O LEU 85 -6.960 17.087 -5.565 1.00 0.00 O +ATOM 831 N ALA 86 -4.755 17.012 -4.998 1.00 0.00 N +ATOM 832 H ALA 86 -4.072 16.641 -4.396 1.00 0.00 H +ATOM 833 CA ALA 86 -4.244 17.957 -6.011 1.00 0.00 C +ATOM 834 CB ALA 86 -3.716 19.219 -5.340 1.00 0.00 C +ATOM 835 C ALA 86 -3.125 17.286 -6.822 1.00 0.00 C +ATOM 836 O ALA 86 -2.504 16.335 -6.335 1.00 0.00 O +ATOM 837 N LYS 87 -2.843 17.812 -8.023 1.00 0.00 N +ATOM 838 H LYS 87 -3.329 18.603 -8.344 1.00 0.00 H +ATOM 839 CA LYS 87 -1.812 17.269 -8.933 1.00 0.00 C +ATOM 840 CB LYS 87 -2.293 17.301 -10.397 1.00 0.00 C +ATOM 841 CG LYS 87 -2.877 18.635 -10.912 1.00 0.00 C +ATOM 842 CD LYS 87 -3.311 18.524 -12.370 1.00 0.00 C +ATOM 843 CE LYS 87 -3.888 19.834 -12.901 1.00 0.00 C +ATOM 844 NZ LYS 87 -5.200 20.202 -12.290 1.00 0.00 N +ATOM 845 HZ1 LYS 87 -5.896 19.454 -12.486 1.00 0.00 H +ATOM 846 HZ2 LYS 87 -5.533 21.099 -12.696 1.00 0.00 H +ATOM 847 HZ3 LYS 87 -5.086 20.308 -11.261 1.00 0.00 H +ATOM 848 C LYS 87 -0.366 17.792 -8.810 1.00 0.00 C +ATOM 849 O LYS 87 -0.143 19.006 -8.719 1.00 0.00 O +ATOM 850 N ILE 88 0.591 16.849 -8.798 1.00 0.00 N +ATOM 851 H ILE 88 0.352 15.898 -8.866 1.00 0.00 H +ATOM 852 CA ILE 88 2.041 17.121 -8.686 1.00 0.00 C +ATOM 853 CB ILE 88 2.661 16.551 -7.307 1.00 0.00 C +ATOM 854 CG2 ILE 88 4.137 17.015 -7.114 1.00 0.00 C +ATOM 855 CG1 ILE 88 1.766 16.863 -6.069 1.00 0.00 C +ATOM 856 CD1 ILE 88 1.607 18.358 -5.576 1.00 0.00 C +ATOM 857 C ILE 88 2.780 16.521 -9.913 1.00 0.00 C +ATOM 858 O ILE 88 3.275 17.275 -10.759 1.00 0.00 O +ATOM 859 N LYS 89 2.842 15.181 -9.989 1.00 0.00 N +ATOM 860 H LYS 89 2.417 14.634 -9.293 1.00 0.00 H +ATOM 861 CA LYS 89 3.516 14.425 -11.067 1.00 0.00 C +ATOM 862 CB LYS 89 4.572 13.481 -10.461 1.00 0.00 C +ATOM 863 CG LYS 89 5.771 14.192 -9.837 1.00 0.00 C +ATOM 864 CD LYS 89 6.726 13.211 -9.178 1.00 0.00 C +ATOM 865 CE LYS 89 7.929 13.931 -8.590 1.00 0.00 C +ATOM 866 NZ LYS 89 8.885 12.990 -7.945 1.00 0.00 N +ATOM 867 HZ1 LYS 89 8.404 12.489 -7.171 1.00 0.00 H +ATOM 868 HZ2 LYS 89 9.225 12.303 -8.648 1.00 0.00 H +ATOM 869 HZ3 LYS 89 9.692 13.523 -7.563 1.00 0.00 H +ATOM 870 C LYS 89 2.473 13.656 -11.912 1.00 0.00 C +ATOM 871 O LYS 89 1.333 14.119 -12.007 1.00 0.00 O +ATOM 872 N THR 90 2.863 12.546 -12.568 1.00 0.00 N +ATOM 873 H THR 90 3.793 12.238 -12.523 1.00 0.00 H +ATOM 874 CA THR 90 1.936 11.739 -13.395 1.00 0.00 C +ATOM 875 CB THR 90 2.246 11.819 -14.927 1.00 0.00 C +ATOM 876 OG1 THR 90 3.615 11.480 -15.165 1.00 0.00 O +ATOM 877 HG1 THR 90 3.705 10.538 -15.043 1.00 0.00 H +ATOM 878 CG2 THR 90 1.965 13.218 -15.466 1.00 0.00 C +ATOM 879 C THR 90 1.697 10.260 -12.965 1.00 0.00 C +ATOM 880 O THR 90 0.529 9.855 -12.927 1.00 0.00 O +ATOM 881 N PRO 91 2.752 9.428 -12.663 1.00 0.00 N +ATOM 882 CD PRO 91 2.264 8.228 -11.932 1.00 0.00 C +ATOM 883 CA PRO 91 4.234 9.474 -12.606 1.00 0.00 C +ATOM 884 CB PRO 91 4.543 8.590 -11.397 1.00 0.00 C +ATOM 885 CG PRO 91 3.527 7.503 -11.498 1.00 0.00 C +ATOM 886 C PRO 91 4.964 8.967 -13.884 1.00 0.00 C +ATOM 887 O PRO 91 6.202 8.961 -13.936 1.00 0.00 O +ATOM 888 N LYS 92 4.174 8.563 -14.891 1.00 0.00 N +ATOM 889 H LYS 92 3.199 8.633 -14.783 1.00 0.00 H +ATOM 890 CA LYS 92 4.640 8.005 -16.184 1.00 0.00 C +ATOM 891 CB LYS 92 3.433 7.721 -17.117 1.00 0.00 C +ATOM 892 CG LYS 92 2.458 8.881 -17.386 1.00 0.00 C +ATOM 893 CD LYS 92 1.329 8.451 -18.316 1.00 0.00 C +ATOM 894 CE LYS 92 0.348 9.587 -18.596 1.00 0.00 C +ATOM 895 NZ LYS 92 -0.464 9.982 -17.406 1.00 0.00 N +ATOM 896 HZ1 LYS 92 0.168 10.299 -16.644 1.00 0.00 H +ATOM 897 HZ2 LYS 92 -1.019 9.166 -17.079 1.00 0.00 H +ATOM 898 HZ3 LYS 92 -1.108 10.756 -17.667 1.00 0.00 H +ATOM 899 C LYS 92 5.809 8.694 -16.947 1.00 0.00 C +ATOM 900 O LYS 92 6.413 8.080 -17.838 1.00 0.00 O +ATOM 901 N GLU 93 6.131 9.937 -16.561 1.00 0.00 N +ATOM 902 H GLU 93 5.630 10.376 -15.839 1.00 0.00 H +ATOM 903 CA GLU 93 7.224 10.727 -17.165 1.00 0.00 C +ATOM 904 CB GLU 93 6.694 12.042 -17.800 1.00 0.00 C +ATOM 905 CG GLU 93 5.811 12.952 -16.921 1.00 0.00 C +ATOM 906 CD GLU 93 5.355 14.202 -17.649 1.00 0.00 C +ATOM 907 OE1 GLU 93 6.070 15.224 -17.584 1.00 0.00 O +ATOM 908 OE2 GLU 93 4.280 14.163 -18.284 1.00 0.00 O +ATOM 909 C GLU 93 8.387 10.996 -16.179 1.00 0.00 C +ATOM 910 O GLU 93 9.475 11.420 -16.596 1.00 0.00 O +ATOM 911 N VAL 94 8.149 10.705 -14.891 1.00 0.00 N +ATOM 912 H VAL 94 7.275 10.350 -14.633 1.00 0.00 H +ATOM 913 CA VAL 94 9.123 10.900 -13.791 1.00 0.00 C +ATOM 914 CB VAL 94 8.410 11.366 -12.451 1.00 0.00 C +ATOM 915 CG1 VAL 94 9.414 12.023 -11.484 1.00 0.00 C +ATOM 916 CG2 VAL 94 7.275 12.346 -12.753 1.00 0.00 C +ATOM 917 C VAL 94 9.949 9.614 -13.529 1.00 0.00 C +ATOM 918 O VAL 94 9.436 8.497 -13.682 1.00 0.00 O +ATOM 919 N ASN 95 11.227 9.805 -13.164 1.00 0.00 N +ATOM 920 H ASN 95 11.586 10.716 -13.086 1.00 0.00 H +ATOM 921 CA ASN 95 12.185 8.726 -12.855 1.00 0.00 C +ATOM 922 CB ASN 95 13.400 8.786 -13.800 1.00 0.00 C +ATOM 923 CG ASN 95 13.035 8.505 -15.254 1.00 0.00 C +ATOM 924 OD1 ASN 95 13.068 7.358 -15.705 1.00 0.00 O +ATOM 925 ND2 ASN 95 12.704 9.558 -15.998 1.00 0.00 N +ATOM 926 HD21 ASN 95 12.467 9.394 -16.934 1.00 0.00 H +ATOM 927 HD22 ASN 95 12.707 10.451 -15.593 1.00 0.00 H +ATOM 928 C ASN 95 12.654 8.868 -11.398 1.00 0.00 C +ATOM 929 O ASN 95 12.628 9.977 -10.852 1.00 0.00 O +ATOM 930 N ALA 96 13.078 7.752 -10.787 1.00 0.00 N +ATOM 931 H ALA 96 13.086 6.895 -11.266 1.00 0.00 H +ATOM 932 CA ALA 96 13.553 7.717 -9.392 1.00 0.00 C +ATOM 933 CB ALA 96 12.842 6.600 -8.617 1.00 0.00 C +ATOM 934 C ALA 96 15.087 7.598 -9.263 1.00 0.00 C +ATOM 935 O ALA 96 15.781 8.620 -9.286 1.00 0.00 O +ATOM 936 N ASP 97 15.601 6.357 -9.157 1.00 0.00 N +ATOM 937 H ASP 97 15.003 5.579 -9.176 1.00 0.00 H +ATOM 938 CA ASP 97 17.039 5.994 -9.020 1.00 0.00 C +ATOM 939 CB ASP 97 17.838 6.300 -10.309 1.00 0.00 C +ATOM 940 CG ASP 97 17.380 5.468 -11.503 1.00 0.00 C +ATOM 941 OD1 ASP 97 17.932 4.365 -11.713 1.00 0.00 O +ATOM 942 OD2 ASP 97 16.480 5.924 -12.243 1.00 0.00 O +ATOM 943 C ASP 97 17.808 6.522 -7.789 1.00 0.00 C +ATOM 944 O ASP 97 18.527 5.752 -7.141 1.00 0.00 O +ATOM 945 N ASP 98 17.649 7.818 -7.483 1.00 0.00 N +ATOM 946 H ASP 98 17.068 8.393 -8.015 1.00 0.00 H +ATOM 947 CA ASP 98 18.321 8.489 -6.351 1.00 0.00 C +ATOM 948 CB ASP 98 19.062 9.749 -6.845 1.00 0.00 C +ATOM 949 CG ASP 98 20.221 9.428 -7.784 1.00 0.00 C +ATOM 950 OD1 ASP 98 20.000 9.373 -9.014 1.00 0.00 O +ATOM 951 OD2 ASP 98 21.358 9.247 -7.294 1.00 0.00 O +ATOM 952 C ASP 98 17.361 8.861 -5.203 1.00 0.00 C +ATOM 953 O ASP 98 17.811 9.293 -4.131 1.00 0.00 O +ATOM 954 N TYR 99 16.057 8.637 -5.417 1.00 0.00 N +ATOM 955 H TYR 99 15.757 8.243 -6.266 1.00 0.00 H +ATOM 956 CA TYR 99 14.993 8.947 -4.441 1.00 0.00 C +ATOM 957 CB TYR 99 13.694 9.327 -5.189 1.00 0.00 C +ATOM 958 CG TYR 99 13.709 10.680 -5.915 1.00 0.00 C +ATOM 959 CD1 TYR 99 13.353 11.878 -5.244 1.00 0.00 C +ATOM 960 CE1 TYR 99 13.340 13.130 -5.921 1.00 0.00 C +ATOM 961 CD2 TYR 99 14.054 10.772 -7.287 1.00 0.00 C +ATOM 962 CE2 TYR 99 14.043 12.019 -7.971 1.00 0.00 C +ATOM 963 CZ TYR 99 13.686 13.188 -7.280 1.00 0.00 C +ATOM 964 OH TYR 99 13.674 14.398 -7.936 1.00 0.00 O +ATOM 965 HH TYR 99 13.931 14.283 -8.854 1.00 0.00 H +ATOM 966 C TYR 99 14.740 7.865 -3.362 1.00 0.00 C +ATOM 967 O TYR 99 13.603 7.668 -2.907 1.00 0.00 O +ATOM 968 N GLN 100 15.837 7.215 -2.944 1.00 0.00 N +ATOM 969 H GLN 100 16.711 7.438 -3.333 1.00 0.00 H +ATOM 970 CA GLN 100 15.923 6.146 -1.915 1.00 0.00 C +ATOM 971 CB GLN 100 16.617 6.685 -0.643 1.00 0.00 C +ATOM 972 CG GLN 100 18.112 6.939 -0.830 1.00 0.00 C +ATOM 973 CD GLN 100 18.767 7.555 0.387 1.00 0.00 C +ATOM 974 OE1 GLN 100 18.891 8.776 0.486 1.00 0.00 O +ATOM 975 NE2 GLN 100 19.202 6.713 1.318 1.00 0.00 N +ATOM 976 HE21 GLN 100 19.632 7.108 2.101 1.00 0.00 H +ATOM 977 HE22 GLN 100 19.081 5.748 1.195 1.00 0.00 H +ATOM 978 C GLN 100 14.702 5.259 -1.553 1.00 0.00 C +ATOM 979 O GLN 100 14.587 4.146 -2.077 1.00 0.00 O +ATOM 980 N ILE 101 13.800 5.761 -0.694 1.00 0.00 N +ATOM 981 H ILE 101 13.918 6.667 -0.335 1.00 0.00 H +ATOM 982 CA ILE 101 12.602 5.024 -0.235 1.00 0.00 C +ATOM 983 CB ILE 101 12.507 5.021 1.373 1.00 0.00 C +ATOM 984 CG2 ILE 101 12.550 6.446 1.953 1.00 0.00 C +ATOM 985 CG1 ILE 101 11.302 4.211 1.895 1.00 0.00 C +ATOM 986 CD1 ILE 101 11.669 2.962 2.689 1.00 0.00 C +ATOM 987 C ILE 101 11.276 5.445 -0.924 1.00 0.00 C +ATOM 988 O ILE 101 11.077 6.625 -1.225 1.00 0.00 O +ATOM 989 N PHE 102 10.418 4.449 -1.192 1.00 0.00 N +ATOM 990 H PHE 102 10.652 3.523 -0.962 1.00 0.00 H +ATOM 991 CA PHE 102 9.095 4.615 -1.828 1.00 0.00 C +ATOM 992 CB PHE 102 9.116 4.052 -3.273 1.00 0.00 C +ATOM 993 CG PHE 102 9.429 5.083 -4.357 1.00 0.00 C +ATOM 994 CD1 PHE 102 10.678 5.755 -4.411 1.00 0.00 C +ATOM 995 CD2 PHE 102 8.472 5.364 -5.357 1.00 0.00 C +ATOM 996 CE1 PHE 102 10.966 6.690 -5.444 1.00 0.00 C +ATOM 997 CE2 PHE 102 8.745 6.295 -6.398 1.00 0.00 C +ATOM 998 CZ PHE 102 9.995 6.960 -6.441 1.00 0.00 C +ATOM 999 C PHE 102 7.990 3.925 -1.007 1.00 0.00 C +ATOM 1000 O PHE 102 8.204 2.822 -0.488 1.00 0.00 O +ATOM 1001 N PHE 103 6.834 4.594 -0.877 1.00 0.00 N +ATOM 1002 H PHE 103 6.726 5.477 -1.284 1.00 0.00 H +ATOM 1003 CA PHE 103 5.658 4.090 -0.136 1.00 0.00 C +ATOM 1004 CB PHE 103 5.375 4.958 1.124 1.00 0.00 C +ATOM 1005 CG PHE 103 6.040 4.466 2.405 1.00 0.00 C +ATOM 1006 CD1 PHE 103 7.372 4.825 2.721 1.00 0.00 C +ATOM 1007 CD2 PHE 103 5.316 3.681 3.333 1.00 0.00 C +ATOM 1008 CE1 PHE 103 7.973 4.412 3.940 1.00 0.00 C +ATOM 1009 CE2 PHE 103 5.903 3.261 4.556 1.00 0.00 C +ATOM 1010 CZ PHE 103 7.235 3.628 4.860 1.00 0.00 C +ATOM 1011 C PHE 103 4.395 4.029 -1.010 1.00 0.00 C +ATOM 1012 O PHE 103 4.166 4.922 -1.830 1.00 0.00 O +ATOM 1013 N ALA 104 3.620 2.946 -0.862 1.00 0.00 N +ATOM 1014 H ALA 104 3.875 2.234 -0.235 1.00 0.00 H +ATOM 1015 CA ALA 104 2.359 2.724 -1.598 1.00 0.00 C +ATOM 1016 CB ALA 104 2.524 1.596 -2.637 1.00 0.00 C +ATOM 1017 C ALA 104 1.243 2.380 -0.598 1.00 0.00 C +ATOM 1018 O ALA 104 1.385 1.426 0.178 1.00 0.00 O +ATOM 1019 N SER 105 0.167 3.183 -0.590 1.00 0.00 N +ATOM 1020 H SER 105 0.113 3.949 -1.203 1.00 0.00 H +ATOM 1021 CA SER 105 -0.989 2.989 0.311 1.00 0.00 C +ATOM 1022 CB SER 105 -0.987 4.020 1.451 1.00 0.00 C +ATOM 1023 OG SER 105 0.215 3.955 2.200 1.00 0.00 O +ATOM 1024 HG SER 105 0.969 4.185 1.652 1.00 0.00 H +ATOM 1025 C SER 105 -2.351 3.026 -0.393 1.00 0.00 C +ATOM 1026 O SER 105 -2.562 3.821 -1.318 1.00 0.00 O +ATOM 1027 N ALA 106 -3.251 2.137 0.053 1.00 0.00 N +ATOM 1028 H ALA 106 -2.998 1.516 0.774 1.00 0.00 H +ATOM 1029 CA ALA 106 -4.636 1.975 -0.441 1.00 0.00 C +ATOM 1030 CB ALA 106 -4.651 1.330 -1.831 1.00 0.00 C +ATOM 1031 C ALA 106 -5.373 1.080 0.564 1.00 0.00 C +ATOM 1032 O ALA 106 -4.731 0.507 1.452 1.00 0.00 O +ATOM 1033 N GLY 107 -6.697 0.947 0.424 1.00 0.00 N +ATOM 1034 H GLY 107 -7.185 1.398 -0.299 1.00 0.00 H +ATOM 1035 CA GLY 107 -7.453 0.117 1.352 1.00 0.00 C +ATOM 1036 C GLY 107 -8.901 -0.239 1.063 1.00 0.00 C +ATOM 1037 O GLY 107 -9.803 0.300 1.714 1.00 0.00 O +ATOM 1038 N HIS 108 -9.115 -1.163 0.116 1.00 0.00 N +ATOM 1039 H HIS 108 -8.340 -1.539 -0.353 1.00 0.00 H +ATOM 1040 CA HIS 108 -10.448 -1.663 -0.282 1.00 0.00 C +ATOM 1041 CB HIS 108 -11.094 -0.810 -1.411 1.00 0.00 C +ATOM 1042 CG HIS 108 -10.174 -0.477 -2.553 1.00 0.00 C +ATOM 1043 CD2 HIS 108 -10.263 -0.754 -3.876 1.00 0.00 C +ATOM 1044 ND1 HIS 108 -9.009 0.243 -2.392 1.00 0.00 N +ATOM 1045 HD1 HIS 108 -8.666 0.591 -1.543 1.00 0.00 H +ATOM 1046 CE1 HIS 108 -8.420 0.394 -3.564 1.00 0.00 C +ATOM 1047 NE2 HIS 108 -9.160 -0.201 -4.481 1.00 0.00 N +ATOM 1048 HE2 HIS 108 -8.956 -0.242 -5.439 1.00 0.00 H +ATOM 1049 C HIS 108 -10.392 -3.141 -0.693 1.00 0.00 C +ATOM 1050 O HIS 108 -11.175 -3.958 -0.194 1.00 0.00 O +ATOM 1051 N GLY 109 -9.464 -3.459 -1.600 1.00 0.00 N +ATOM 1052 H GLY 109 -8.858 -2.780 -1.970 1.00 0.00 H +ATOM 1053 CA GLY 109 -9.290 -4.816 -2.094 1.00 0.00 C +ATOM 1054 C GLY 109 -8.450 -4.846 -3.355 1.00 0.00 C +ATOM 1055 O GLY 109 -7.243 -5.107 -3.288 1.00 0.00 O +ATOM 1056 N THR 110 -9.106 -4.612 -4.499 1.00 0.00 N +ATOM 1057 H THR 110 -10.073 -4.453 -4.466 1.00 0.00 H +ATOM 1058 CA THR 110 -8.471 -4.577 -5.829 1.00 0.00 C +ATOM 1059 CB THR 110 -9.093 -5.643 -6.824 1.00 0.00 C +ATOM 1060 OG1 THR 110 -8.561 -5.457 -8.144 1.00 0.00 O +ATOM 1061 HG1 THR 110 -7.611 -5.597 -8.142 1.00 0.00 H +ATOM 1062 CG2 THR 110 -10.637 -5.589 -6.862 1.00 0.00 C +ATOM 1063 C THR 110 -8.522 -3.143 -6.401 1.00 0.00 C +ATOM 1064 O THR 110 -9.563 -2.477 -6.318 1.00 0.00 O +ATOM 1065 N LEU 111 -7.399 -2.693 -6.973 1.00 0.00 N +ATOM 1066 H LEU 111 -6.604 -3.267 -7.031 1.00 0.00 H +ATOM 1067 CA LEU 111 -7.259 -1.345 -7.547 1.00 0.00 C +ATOM 1068 CB LEU 111 -5.881 -0.756 -7.185 1.00 0.00 C +ATOM 1069 CG LEU 111 -5.812 0.439 -6.226 1.00 0.00 C +ATOM 1070 CD1 LEU 111 -4.571 0.315 -5.361 1.00 0.00 C +ATOM 1071 CD2 LEU 111 -5.842 1.772 -6.994 1.00 0.00 C +ATOM 1072 C LEU 111 -7.494 -1.224 -9.059 1.00 0.00 C +ATOM 1073 O LEU 111 -7.951 -0.172 -9.524 1.00 0.00 O +ATOM 1074 N PHE 112 -7.185 -2.297 -9.809 1.00 0.00 N +ATOM 1075 H PHE 112 -6.840 -3.106 -9.371 1.00 0.00 H +ATOM 1076 CA PHE 112 -7.309 -2.408 -11.291 1.00 0.00 C +ATOM 1077 CB PHE 112 -8.747 -2.085 -11.800 1.00 0.00 C +ATOM 1078 CG PHE 112 -9.838 -3.015 -11.274 1.00 0.00 C +ATOM 1079 CD1 PHE 112 -10.164 -4.212 -11.957 1.00 0.00 C +ATOM 1080 CD2 PHE 112 -10.578 -2.677 -10.116 1.00 0.00 C +ATOM 1081 CE1 PHE 112 -11.210 -5.059 -11.497 1.00 0.00 C +ATOM 1082 CE2 PHE 112 -11.627 -3.514 -9.643 1.00 0.00 C +ATOM 1083 CZ PHE 112 -11.943 -4.708 -10.336 1.00 0.00 C +ATOM 1084 C PHE 112 -6.275 -1.579 -12.080 1.00 0.00 C +ATOM 1085 O PHE 112 -5.816 -2.014 -13.145 1.00 0.00 O +ATOM 1086 N ASP 113 -5.917 -0.404 -11.542 1.00 0.00 N +ATOM 1087 H ASP 113 -6.304 -0.084 -10.704 1.00 0.00 H +ATOM 1088 CA ASP 113 -4.940 0.523 -12.142 1.00 0.00 C +ATOM 1089 CB ASP 113 -5.453 1.987 -12.087 1.00 0.00 C +ATOM 1090 CG ASP 113 -6.008 2.391 -10.716 1.00 0.00 C +ATOM 1091 OD1 ASP 113 -5.234 2.921 -9.891 1.00 0.00 O +ATOM 1092 OD2 ASP 113 -7.221 2.204 -10.480 1.00 0.00 O +ATOM 1093 C ASP 113 -3.516 0.387 -11.552 1.00 0.00 C +ATOM 1094 O ASP 113 -2.546 0.875 -12.148 1.00 0.00 O +ATOM 1095 N TYR 114 -3.414 -0.296 -10.401 1.00 0.00 N +ATOM 1096 H TYR 114 -4.216 -0.665 -9.971 1.00 0.00 H +ATOM 1097 CA TYR 114 -2.139 -0.545 -9.700 1.00 0.00 C +ATOM 1098 CB TYR 114 -2.268 -0.244 -8.187 1.00 0.00 C +ATOM 1099 CG TYR 114 -2.017 1.194 -7.722 1.00 0.00 C +ATOM 1100 CD1 TYR 114 -2.620 2.312 -8.357 1.00 0.00 C +ATOM 1101 CE1 TYR 114 -2.399 3.636 -7.888 1.00 0.00 C +ATOM 1102 CD2 TYR 114 -1.189 1.441 -6.607 1.00 0.00 C +ATOM 1103 CE2 TYR 114 -0.961 2.761 -6.130 1.00 0.00 C +ATOM 1104 CZ TYR 114 -1.569 3.848 -6.777 1.00 0.00 C +ATOM 1105 OH TYR 114 -1.344 5.127 -6.324 1.00 0.00 O +ATOM 1106 HH TYR 114 -0.750 5.111 -5.571 1.00 0.00 H +ATOM 1107 C TYR 114 -1.604 -1.985 -9.945 1.00 0.00 C +ATOM 1108 O TYR 114 -0.444 -2.118 -10.356 1.00 0.00 O +ATOM 1109 N PRO 115 -2.417 -3.076 -9.703 1.00 0.00 N +ATOM 1110 CD PRO 115 -3.726 -3.224 -9.023 1.00 0.00 C +ATOM 1111 CA PRO 115 -1.864 -4.427 -9.959 1.00 0.00 C +ATOM 1112 CB PRO 115 -2.771 -5.347 -9.124 1.00 0.00 C +ATOM 1113 CG PRO 115 -3.481 -4.424 -8.161 1.00 0.00 C +ATOM 1114 C PRO 115 -1.927 -4.803 -11.458 1.00 0.00 C +ATOM 1115 O PRO 115 -2.842 -4.356 -12.162 1.00 0.00 O +ATOM 1116 N LYS 116 -0.951 -5.597 -11.932 1.00 0.00 N +ATOM 1117 H LYS 116 -0.251 -5.917 -11.321 1.00 0.00 H +ATOM 1118 CA LYS 116 -0.816 -6.061 -13.342 1.00 0.00 C +ATOM 1119 CB LYS 116 -1.955 -7.028 -13.747 1.00 0.00 C +ATOM 1120 CG LYS 116 -1.933 -8.373 -13.030 1.00 0.00 C +ATOM 1121 CD LYS 116 -3.085 -9.263 -13.485 1.00 0.00 C +ATOM 1122 CE LYS 116 -3.082 -10.617 -12.780 1.00 0.00 C +ATOM 1123 NZ LYS 116 -3.408 -10.534 -11.324 1.00 0.00 N +ATOM 1124 HZ1 LYS 116 -4.356 -10.123 -11.204 1.00 0.00 H +ATOM 1125 HZ2 LYS 116 -2.707 -9.933 -10.846 1.00 0.00 H +ATOM 1126 HZ3 LYS 116 -3.388 -11.487 -10.909 1.00 0.00 H +ATOM 1127 C LYS 116 -0.673 -4.904 -14.365 1.00 0.00 C +ATOM 1128 O LYS 116 -0.674 -5.130 -15.586 1.00 0.00 O +ATOM 1129 N ALA 117 -0.489 -3.684 -13.836 1.00 0.00 N +ATOM 1130 H ALA 117 -0.435 -3.562 -12.865 1.00 0.00 H +ATOM 1131 CA ALA 117 -0.330 -2.437 -14.610 1.00 0.00 C +ATOM 1132 CB ALA 117 -0.872 -1.257 -13.810 1.00 0.00 C +ATOM 1133 C ALA 117 1.146 -2.204 -14.972 1.00 0.00 C +ATOM 1134 O ALA 117 2.024 -2.425 -14.137 1.00 0.00 O +ATOM 1135 N LYS 118 1.397 -1.738 -16.202 1.00 0.00 N +ATOM 1136 H LYS 118 0.647 -1.541 -16.806 1.00 0.00 H +ATOM 1137 CA LYS 118 2.752 -1.485 -16.737 1.00 0.00 C +ATOM 1138 CB LYS 118 2.703 -1.316 -18.264 1.00 0.00 C +ATOM 1139 CG LYS 118 2.372 -2.589 -19.037 1.00 0.00 C +ATOM 1140 CD LYS 118 2.344 -2.333 -20.540 1.00 0.00 C +ATOM 1141 CE LYS 118 2.015 -3.595 -21.334 1.00 0.00 C +ATOM 1142 NZ LYS 118 3.094 -4.627 -21.290 1.00 0.00 N +ATOM 1143 HZ1 LYS 118 3.259 -4.914 -20.304 1.00 0.00 H +ATOM 1144 HZ2 LYS 118 2.805 -5.455 -21.849 1.00 0.00 H +ATOM 1145 HZ3 LYS 118 3.970 -4.230 -21.686 1.00 0.00 H +ATOM 1146 C LYS 118 3.568 -0.334 -16.120 1.00 0.00 C +ATOM 1147 O LYS 118 4.735 -0.539 -15.772 1.00 0.00 O +ATOM 1148 N ASP 119 2.942 0.838 -15.935 1.00 0.00 N +ATOM 1149 H ASP 119 1.991 0.926 -16.168 1.00 0.00 H +ATOM 1150 CA ASP 119 3.606 2.039 -15.384 1.00 0.00 C +ATOM 1151 CB ASP 119 2.761 3.306 -15.659 1.00 0.00 C +ATOM 1152 CG ASP 119 1.295 3.166 -15.229 1.00 0.00 C +ATOM 1153 OD1 ASP 119 0.985 3.468 -14.056 1.00 0.00 O +ATOM 1154 OD2 ASP 119 0.459 2.767 -16.069 1.00 0.00 O +ATOM 1155 C ASP 119 4.049 1.986 -13.905 1.00 0.00 C +ATOM 1156 O ASP 119 5.213 2.274 -13.609 1.00 0.00 O +ATOM 1157 N LEU 120 3.148 1.549 -13.012 1.00 0.00 N +ATOM 1158 H LEU 120 2.252 1.281 -13.314 1.00 0.00 H +ATOM 1159 CA LEU 120 3.422 1.439 -11.564 1.00 0.00 C +ATOM 1160 CB LEU 120 2.112 1.241 -10.770 1.00 0.00 C +ATOM 1161 CG LEU 120 1.985 1.808 -9.340 1.00 0.00 C +ATOM 1162 CD1 LEU 120 0.829 2.797 -9.261 1.00 0.00 C +ATOM 1163 CD2 LEU 120 1.809 0.677 -8.326 1.00 0.00 C +ATOM 1164 C LEU 120 4.430 0.312 -11.260 1.00 0.00 C +ATOM 1165 O LEU 120 5.301 0.477 -10.395 1.00 0.00 O +ATOM 1166 N GLN 121 4.303 -0.810 -11.984 1.00 0.00 N +ATOM 1167 H GLN 121 3.584 -0.884 -12.651 1.00 0.00 H +ATOM 1168 CA GLN 121 5.193 -1.977 -11.847 1.00 0.00 C +ATOM 1169 CB GLN 121 4.624 -3.204 -12.565 1.00 0.00 C +ATOM 1170 CG GLN 121 3.520 -3.926 -11.800 1.00 0.00 C +ATOM 1171 CD GLN 121 3.163 -5.269 -12.415 1.00 0.00 C +ATOM 1172 OE1 GLN 121 3.569 -6.317 -11.915 1.00 0.00 O +ATOM 1173 NE2 GLN 121 2.399 -5.244 -13.503 1.00 0.00 N +ATOM 1174 HE21 GLN 121 2.164 -6.104 -13.909 1.00 0.00 H +ATOM 1175 HE22 GLN 121 2.098 -4.385 -13.861 1.00 0.00 H +ATOM 1176 C GLN 121 6.612 -1.646 -12.341 1.00 0.00 C +ATOM 1177 O GLN 121 7.595 -2.138 -11.773 1.00 0.00 O +ATOM 1178 N ASP 122 6.699 -0.817 -13.395 1.00 0.00 N +ATOM 1179 H ASP 122 5.878 -0.496 -13.838 1.00 0.00 H +ATOM 1180 CA ASP 122 7.976 -0.349 -13.978 1.00 0.00 C +ATOM 1181 CB ASP 122 7.753 0.340 -15.333 1.00 0.00 C +ATOM 1182 CG ASP 122 7.937 -0.607 -16.516 1.00 0.00 C +ATOM 1183 OD1 ASP 122 9.066 -0.684 -17.048 1.00 0.00 O +ATOM 1184 OD2 ASP 122 6.955 -1.263 -16.928 1.00 0.00 O +ATOM 1185 C ASP 122 8.721 0.598 -13.019 1.00 0.00 C +ATOM 1186 O ASP 122 9.952 0.527 -12.919 1.00 0.00 O +ATOM 1187 N ILE 123 7.963 1.450 -12.304 1.00 0.00 N +ATOM 1188 H ILE 123 6.987 1.464 -12.449 1.00 0.00 H +ATOM 1189 CA ILE 123 8.509 2.406 -11.309 1.00 0.00 C +ATOM 1190 CB ILE 123 7.419 3.494 -10.831 1.00 0.00 C +ATOM 1191 CG2 ILE 123 7.955 4.379 -9.663 1.00 0.00 C +ATOM 1192 CG1 ILE 123 6.872 4.336 -12.020 1.00 0.00 C +ATOM 1193 CD1 ILE 123 7.823 5.369 -12.751 1.00 0.00 C +ATOM 1194 C ILE 123 9.054 1.577 -10.124 1.00 0.00 C +ATOM 1195 O ILE 123 10.170 1.830 -9.664 1.00 0.00 O +ATOM 1196 N ALA 124 8.303 0.535 -9.730 1.00 0.00 N +ATOM 1197 H ALA 124 7.449 0.351 -10.184 1.00 0.00 H +ATOM 1198 CA ALA 124 8.653 -0.388 -8.629 1.00 0.00 C +ATOM 1199 CB ALA 124 7.486 -1.332 -8.340 1.00 0.00 C +ATOM 1200 C ALA 124 9.916 -1.192 -8.985 1.00 0.00 C +ATOM 1201 O ALA 124 10.780 -1.412 -8.129 1.00 0.00 O +ATOM 1202 N SER 125 10.028 -1.557 -10.272 1.00 0.00 N +ATOM 1203 H SER 125 9.312 -1.316 -10.902 1.00 0.00 H +ATOM 1204 CA SER 125 11.165 -2.307 -10.842 1.00 0.00 C +ATOM 1205 CB SER 125 10.856 -2.732 -12.285 1.00 0.00 C +ATOM 1206 OG SER 125 11.853 -3.600 -12.803 1.00 0.00 O +ATOM 1207 HG SER 125 12.701 -3.150 -12.846 1.00 0.00 H +ATOM 1208 C SER 125 12.419 -1.415 -10.802 1.00 0.00 C +ATOM 1209 O SER 125 13.530 -1.911 -10.580 1.00 0.00 O +ATOM 1210 N GLU 126 12.211 -0.105 -11.018 1.00 0.00 N +ATOM 1211 H GLU 126 11.301 0.214 -11.220 1.00 0.00 H +ATOM 1212 CA GLU 126 13.268 0.927 -10.994 1.00 0.00 C +ATOM 1213 CB GLU 126 12.753 2.260 -11.554 1.00 0.00 C +ATOM 1214 CG GLU 126 12.612 2.296 -13.072 1.00 0.00 C +ATOM 1215 CD GLU 126 12.101 3.631 -13.581 1.00 0.00 C +ATOM 1216 OE1 GLU 126 12.933 4.517 -13.871 1.00 0.00 O +ATOM 1217 OE2 GLU 126 10.868 3.794 -13.695 1.00 0.00 O +ATOM 1218 C GLU 126 13.835 1.137 -9.579 1.00 0.00 C +ATOM 1219 O GLU 126 15.046 1.328 -9.430 1.00 0.00 O +ATOM 1220 N ILE 127 12.961 1.087 -8.558 1.00 0.00 N +ATOM 1221 H ILE 127 12.003 0.953 -8.748 1.00 0.00 H +ATOM 1222 CA ILE 127 13.352 1.239 -7.135 1.00 0.00 C +ATOM 1223 CB ILE 127 12.106 1.433 -6.138 1.00 0.00 C +ATOM 1224 CG2 ILE 127 12.564 2.069 -4.794 1.00 0.00 C +ATOM 1225 CG1 ILE 127 10.915 2.198 -6.779 1.00 0.00 C +ATOM 1226 CD1 ILE 127 11.124 3.664 -7.303 1.00 0.00 C +ATOM 1227 C ILE 127 14.172 -0.008 -6.725 1.00 0.00 C +ATOM 1228 O ILE 127 15.169 0.117 -6.007 1.00 0.00 O +ATOM 1229 N TYR 128 13.742 -1.186 -7.206 1.00 0.00 N +ATOM 1230 H TYR 128 12.931 -1.213 -7.764 1.00 0.00 H +ATOM 1231 CA TYR 128 14.395 -2.489 -6.955 1.00 0.00 C +ATOM 1232 CB TYR 128 13.472 -3.663 -7.357 1.00 0.00 C +ATOM 1233 CG TYR 128 12.525 -4.187 -6.279 1.00 0.00 C +ATOM 1234 CD1 TYR 128 12.952 -5.159 -5.339 1.00 0.00 C +ATOM 1235 CE1 TYR 128 12.064 -5.677 -4.362 1.00 0.00 C +ATOM 1236 CD2 TYR 128 11.183 -3.748 -6.213 1.00 0.00 C +ATOM 1237 CE2 TYR 128 10.290 -4.260 -5.242 1.00 0.00 C +ATOM 1238 CZ TYR 128 10.739 -5.221 -4.325 1.00 0.00 C +ATOM 1239 OH TYR 128 9.863 -5.723 -3.396 1.00 0.00 O +ATOM 1240 HH TYR 128 10.303 -6.368 -2.836 1.00 0.00 H +ATOM 1241 C TYR 128 15.763 -2.654 -7.638 1.00 0.00 C +ATOM 1242 O TYR 128 16.668 -3.273 -7.065 1.00 0.00 O +ATOM 1243 N ALA 129 15.894 -2.095 -8.850 1.00 0.00 N +ATOM 1244 H ALA 129 15.135 -1.610 -9.245 1.00 0.00 H +ATOM 1245 CA ALA 129 17.120 -2.145 -9.677 1.00 0.00 C +ATOM 1246 CB ALA 129 16.865 -1.489 -11.029 1.00 0.00 C +ATOM 1247 C ALA 129 18.358 -1.519 -9.009 1.00 0.00 C +ATOM 1248 O ALA 129 19.468 -2.037 -9.165 1.00 0.00 O +ATOM 1249 N ASN 130 18.147 -0.420 -8.271 1.00 0.00 N +ATOM 1250 H ASN 130 17.243 -0.044 -8.188 1.00 0.00 H +ATOM 1251 CA ASN 130 19.208 0.303 -7.541 1.00 0.00 C +ATOM 1252 CB ASN 130 19.235 1.808 -7.924 1.00 0.00 C +ATOM 1253 CG ASN 130 17.847 2.461 -7.942 1.00 0.00 C +ATOM 1254 OD1 ASN 130 17.299 2.825 -6.899 1.00 0.00 O +ATOM 1255 ND2 ASN 130 17.294 2.632 -9.137 1.00 0.00 N +ATOM 1256 HD21 ASN 130 16.407 3.047 -9.170 1.00 0.00 H +ATOM 1257 HD22 ASN 130 17.780 2.342 -9.938 1.00 0.00 H +ATOM 1258 C ASN 130 19.079 0.099 -6.016 1.00 0.00 C +ATOM 1259 O ASN 130 18.180 -0.622 -5.569 1.00 0.00 O +ATOM 1260 N GLY 131 19.970 0.730 -5.239 1.00 0.00 N +ATOM 1261 H GLY 131 20.668 1.297 -5.635 1.00 0.00 H +ATOM 1262 CA GLY 131 19.963 0.619 -3.781 1.00 0.00 C +ATOM 1263 C GLY 131 18.933 1.483 -3.069 1.00 0.00 C +ATOM 1264 O GLY 131 19.265 2.554 -2.549 1.00 0.00 O +ATOM 1265 N GLY 132 17.689 1.001 -3.058 1.00 0.00 N +ATOM 1266 H GLY 132 17.495 0.143 -3.492 1.00 0.00 H +ATOM 1267 CA GLY 132 16.586 1.701 -2.418 1.00 0.00 C +ATOM 1268 C GLY 132 15.531 0.721 -1.933 1.00 0.00 C +ATOM 1269 O GLY 132 15.147 -0.189 -2.678 1.00 0.00 O +ATOM 1270 N VAL 133 15.071 0.912 -0.689 1.00 0.00 N +ATOM 1271 H VAL 133 15.426 1.664 -0.171 1.00 0.00 H +ATOM 1272 CA VAL 133 14.053 0.060 -0.041 1.00 0.00 C +ATOM 1273 CB VAL 133 14.347 -0.159 1.492 1.00 0.00 C +ATOM 1274 CG1 VAL 133 15.435 -1.208 1.661 1.00 0.00 C +ATOM 1275 CG2 VAL 133 14.781 1.149 2.190 1.00 0.00 C +ATOM 1276 C VAL 133 12.589 0.508 -0.262 1.00 0.00 C +ATOM 1277 O VAL 133 12.292 1.709 -0.232 1.00 0.00 O +ATOM 1278 N VAL 134 11.705 -0.472 -0.507 1.00 0.00 N +ATOM 1279 H VAL 134 11.998 -1.409 -0.528 1.00 0.00 H +ATOM 1280 CA VAL 134 10.266 -0.255 -0.758 1.00 0.00 C +ATOM 1281 CB VAL 134 9.844 -0.846 -2.187 1.00 0.00 C +ATOM 1282 CG1 VAL 134 10.017 -2.369 -2.255 1.00 0.00 C +ATOM 1283 CG2 VAL 134 8.427 -0.404 -2.596 1.00 0.00 C +ATOM 1284 C VAL 134 9.379 -0.795 0.397 1.00 0.00 C +ATOM 1285 O VAL 134 9.596 -1.915 0.878 1.00 0.00 O +ATOM 1286 N ALA 135 8.416 0.027 0.838 1.00 0.00 N +ATOM 1287 H ALA 135 8.312 0.924 0.452 1.00 0.00 H +ATOM 1288 CA ALA 135 7.462 -0.329 1.904 1.00 0.00 C +ATOM 1289 CB ALA 135 7.749 0.476 3.182 1.00 0.00 C +ATOM 1290 C ALA 135 6.030 -0.069 1.412 1.00 0.00 C +ATOM 1291 O ALA 135 5.727 1.035 0.950 1.00 0.00 O +ATOM 1292 N ALA 136 5.175 -1.099 1.481 1.00 0.00 N +ATOM 1293 H ALA 136 5.472 -1.968 1.830 1.00 0.00 H +ATOM 1294 CA ALA 136 3.763 -1.030 1.056 1.00 0.00 C +ATOM 1295 CB ALA 136 3.560 -1.798 -0.247 1.00 0.00 C +ATOM 1296 C ALA 136 2.829 -1.573 2.144 1.00 0.00 C +ATOM 1297 O ALA 136 3.174 -2.554 2.809 1.00 0.00 O +ATOM 1298 N VAL 137 1.656 -0.944 2.306 1.00 0.00 N +ATOM 1299 H VAL 137 1.423 -0.174 1.742 1.00 0.00 H +ATOM 1300 CA VAL 137 0.644 -1.337 3.313 1.00 0.00 C +ATOM 1301 CB VAL 137 0.264 -0.140 4.283 1.00 0.00 C +ATOM 1302 CG1 VAL 137 1.449 0.242 5.128 1.00 0.00 C +ATOM 1303 CG2 VAL 137 -0.228 1.092 3.514 1.00 0.00 C +ATOM 1304 C VAL 137 -0.633 -1.963 2.706 1.00 0.00 C +ATOM 1305 O VAL 137 -1.055 -1.567 1.612 1.00 0.00 O +ATOM 1306 N CYS 138 -1.226 -2.931 3.432 1.00 0.00 N +ATOM 1307 H CYS 138 -0.825 -3.201 4.287 1.00 0.00 H +ATOM 1308 CA CYS 138 -2.469 -3.676 3.083 1.00 0.00 C +ATOM 1309 CB CYS 138 -3.711 -2.908 3.591 1.00 0.00 C +ATOM 1310 SG CYS 138 -5.342 -3.476 3.030 1.00 0.00 S +ATOM 1311 C CYS 138 -2.634 -4.160 1.623 1.00 0.00 C +ATOM 1312 O CYS 138 -2.449 -5.346 1.330 1.00 0.00 O +ATOM 1313 N HIS 139 -2.998 -3.220 0.744 1.00 0.00 N +ATOM 1314 H HIS 139 -3.127 -2.304 1.082 1.00 0.00 H +ATOM 1315 CA HIS 139 -3.222 -3.392 -0.696 1.00 0.00 C +ATOM 1316 CB HIS 139 -3.949 -2.155 -1.238 1.00 0.00 C +ATOM 1317 CG HIS 139 -4.793 -2.416 -2.455 1.00 0.00 C +ATOM 1318 CD2 HIS 139 -6.099 -2.158 -2.707 1.00 0.00 C +ATOM 1319 ND1 HIS 139 -4.296 -3.010 -3.597 1.00 0.00 N +ATOM 1320 HD1 HIS 139 -3.380 -3.330 -3.714 1.00 0.00 H +ATOM 1321 CE1 HIS 139 -5.257 -3.106 -4.498 1.00 0.00 C +ATOM 1322 NE2 HIS 139 -6.361 -2.596 -3.982 1.00 0.00 N +ATOM 1323 HE2 HIS 139 -7.228 -2.535 -4.432 1.00 0.00 H +ATOM 1324 C HIS 139 -1.927 -3.663 -1.474 1.00 0.00 C +ATOM 1325 O HIS 139 -1.946 -4.333 -2.517 1.00 0.00 O +ATOM 1326 N GLY 140 -0.819 -3.119 -0.955 1.00 0.00 N +ATOM 1327 H GLY 140 -0.848 -2.610 -0.115 1.00 0.00 H +ATOM 1328 CA GLY 140 0.492 -3.239 -1.584 1.00 0.00 C +ATOM 1329 C GLY 140 0.972 -4.657 -1.903 1.00 0.00 C +ATOM 1330 O GLY 140 1.436 -4.834 -3.034 1.00 0.00 O +ATOM 1331 N PRO 141 0.871 -5.680 -0.997 1.00 0.00 N +ATOM 1332 CD PRO 141 0.594 -5.601 0.455 1.00 0.00 C +ATOM 1333 CA PRO 141 1.320 -7.051 -1.317 1.00 0.00 C +ATOM 1334 CB PRO 141 0.975 -7.824 -0.047 1.00 0.00 C +ATOM 1335 CG PRO 141 1.281 -6.848 0.978 1.00 0.00 C +ATOM 1336 C PRO 141 0.570 -7.597 -2.543 1.00 0.00 C +ATOM 1337 O PRO 141 1.139 -8.345 -3.346 1.00 0.00 O +ATOM 1338 N ALA 142 -0.706 -7.201 -2.660 1.00 0.00 N +ATOM 1339 H ALA 142 -1.110 -6.628 -1.971 1.00 0.00 H +ATOM 1340 CA ALA 142 -1.588 -7.566 -3.779 1.00 0.00 C +ATOM 1341 CB ALA 142 -3.031 -7.187 -3.459 1.00 0.00 C +ATOM 1342 C ALA 142 -1.115 -6.877 -5.074 1.00 0.00 C +ATOM 1343 O ALA 142 -1.151 -7.492 -6.147 1.00 0.00 O +ATOM 1344 N ILE 143 -0.679 -5.610 -4.955 1.00 0.00 N +ATOM 1345 H ILE 143 -0.694 -5.179 -4.069 1.00 0.00 H +ATOM 1346 CA ILE 143 -0.172 -4.802 -6.093 1.00 0.00 C +ATOM 1347 CB ILE 143 -0.139 -3.250 -5.757 1.00 0.00 C +ATOM 1348 CG2 ILE 143 0.390 -2.426 -6.969 1.00 0.00 C +ATOM 1349 CG1 ILE 143 -1.543 -2.759 -5.359 1.00 0.00 C +ATOM 1350 CD1 ILE 143 -1.572 -1.568 -4.382 1.00 0.00 C +ATOM 1351 C ILE 143 1.213 -5.247 -6.632 1.00 0.00 C +ATOM 1352 O ILE 143 1.345 -5.450 -7.844 1.00 0.00 O +ATOM 1353 N PHE 144 2.220 -5.396 -5.751 1.00 0.00 N +ATOM 1354 H PHE 144 2.076 -5.234 -4.798 1.00 0.00 H +ATOM 1355 CA PHE 144 3.574 -5.808 -6.175 1.00 0.00 C +ATOM 1356 CB PHE 144 4.718 -5.236 -5.276 1.00 0.00 C +ATOM 1357 CG PHE 144 4.695 -5.648 -3.805 1.00 0.00 C +ATOM 1358 CD1 PHE 144 5.093 -6.944 -3.394 1.00 0.00 C +ATOM 1359 CD2 PHE 144 4.402 -4.693 -2.809 1.00 0.00 C +ATOM 1360 CE1 PHE 144 5.205 -7.274 -2.021 1.00 0.00 C +ATOM 1361 CE2 PHE 144 4.510 -5.012 -1.429 1.00 0.00 C +ATOM 1362 CZ PHE 144 4.915 -6.306 -1.035 1.00 0.00 C +ATOM 1363 C PHE 144 3.833 -7.261 -6.617 1.00 0.00 C +ATOM 1364 O PHE 144 4.603 -7.481 -7.558 1.00 0.00 O +ATOM 1365 N ASP 145 3.179 -8.231 -5.960 1.00 0.00 N +ATOM 1366 H ASP 145 2.566 -7.996 -5.228 1.00 0.00 H +ATOM 1367 CA ASP 145 3.323 -9.669 -6.274 1.00 0.00 C +ATOM 1368 CB ASP 145 2.684 -10.541 -5.172 1.00 0.00 C +ATOM 1369 CG ASP 145 3.507 -10.575 -3.890 1.00 0.00 C +ATOM 1370 OD1 ASP 145 3.417 -9.628 -3.078 1.00 0.00 O +ATOM 1371 OD2 ASP 145 4.234 -11.570 -3.683 1.00 0.00 O +ATOM 1372 C ASP 145 2.781 -10.038 -7.673 1.00 0.00 C +ATOM 1373 O ASP 145 1.565 -10.019 -7.911 1.00 0.00 O +ATOM 1374 N GLY 146 3.714 -10.295 -8.596 1.00 0.00 N +ATOM 1375 H GLY 146 4.671 -10.263 -8.375 1.00 0.00 H +ATOM 1376 CA GLY 146 3.391 -10.637 -9.977 1.00 0.00 C +ATOM 1377 C GLY 146 4.008 -9.610 -10.915 1.00 0.00 C +ATOM 1378 O GLY 146 3.298 -9.001 -11.724 1.00 0.00 O +ATOM 1379 N LEU 147 5.331 -9.437 -10.797 1.00 0.00 N +ATOM 1380 H LEU 147 5.820 -9.983 -10.145 1.00 0.00 H +ATOM 1381 CA LEU 147 6.126 -8.477 -11.582 1.00 0.00 C +ATOM 1382 CB LEU 147 7.146 -7.771 -10.640 1.00 0.00 C +ATOM 1383 CG LEU 147 7.732 -6.324 -10.606 1.00 0.00 C +ATOM 1384 CD1 LEU 147 8.545 -5.950 -11.854 1.00 0.00 C +ATOM 1385 CD2 LEU 147 6.665 -5.267 -10.300 1.00 0.00 C +ATOM 1386 C LEU 147 6.878 -9.139 -12.756 1.00 0.00 C +ATOM 1387 O LEU 147 6.852 -10.364 -12.903 1.00 0.00 O +ATOM 1388 N THR 148 7.462 -8.295 -13.622 1.00 0.00 N +ATOM 1389 H THR 148 7.350 -7.327 -13.515 1.00 0.00 H +ATOM 1390 CA THR 148 8.272 -8.687 -14.793 1.00 0.00 C +ATOM 1391 CB THR 148 7.415 -8.835 -16.128 1.00 0.00 C +ATOM 1392 OG1 THR 148 8.283 -9.051 -17.249 1.00 0.00 O +ATOM 1393 HG1 THR 148 8.774 -9.869 -17.136 1.00 0.00 H +ATOM 1394 CG2 THR 148 6.508 -7.611 -16.389 1.00 0.00 C +ATOM 1395 C THR 148 9.412 -7.649 -14.931 1.00 0.00 C +ATOM 1396 O THR 148 9.150 -6.437 -14.946 1.00 0.00 O +ATOM 1397 N ASP 149 10.660 -8.134 -14.992 1.00 0.00 N +ATOM 1398 H ASP 149 10.817 -9.098 -14.943 1.00 0.00 H +ATOM 1399 CA ASP 149 11.862 -7.287 -15.102 1.00 0.00 C +ATOM 1400 CB ASP 149 12.996 -7.850 -14.220 1.00 0.00 C +ATOM 1401 CG ASP 149 12.676 -7.789 -12.729 1.00 0.00 C +ATOM 1402 OD1 ASP 149 13.010 -6.771 -12.085 1.00 0.00 O +ATOM 1403 OD2 ASP 149 12.107 -8.768 -12.198 1.00 0.00 O +ATOM 1404 C ASP 149 12.353 -7.030 -16.544 1.00 0.00 C +ATOM 1405 O ASP 149 12.227 -5.901 -17.034 1.00 0.00 O +ATOM 1406 N LYS 150 12.902 -8.061 -17.205 1.00 0.00 N +ATOM 1407 H LYS 150 12.980 -8.936 -16.769 1.00 0.00 H +ATOM 1408 CA LYS 150 13.419 -7.969 -18.587 1.00 0.00 C +ATOM 1409 CB LYS 150 14.969 -8.068 -18.627 1.00 0.00 C +ATOM 1410 CG LYS 150 15.622 -9.201 -17.805 1.00 0.00 C +ATOM 1411 CD LYS 150 17.136 -9.176 -17.936 1.00 0.00 C +ATOM 1412 CE LYS 150 17.779 -10.291 -17.127 1.00 0.00 C +ATOM 1413 NZ LYS 150 19.263 -10.280 -17.247 1.00 0.00 N +ATOM 1414 HZ1 LYS 150 19.531 -10.404 -18.244 1.00 0.00 H +ATOM 1415 HZ2 LYS 150 19.662 -11.055 -16.680 1.00 0.00 H +ATOM 1416 HZ3 LYS 150 19.631 -9.371 -16.899 1.00 0.00 H +ATOM 1417 C LYS 150 12.763 -8.969 -19.565 1.00 0.00 C +ATOM 1418 O LYS 150 12.130 -8.550 -20.542 1.00 0.00 O +ATOM 1419 N LYS 151 12.925 -10.271 -19.288 1.00 0.00 N +ATOM 1420 H LYS 151 13.442 -10.546 -18.500 1.00 0.00 H +ATOM 1421 CA LYS 151 12.377 -11.375 -20.101 1.00 0.00 C +ATOM 1422 CB LYS 151 13.498 -12.378 -20.490 1.00 0.00 C +ATOM 1423 CG LYS 151 14.440 -12.855 -19.364 1.00 0.00 C +ATOM 1424 CD LYS 151 15.482 -13.828 -19.891 1.00 0.00 C +ATOM 1425 CE LYS 151 16.410 -14.298 -18.782 1.00 0.00 C +ATOM 1426 NZ LYS 151 17.438 -15.251 -19.284 1.00 0.00 N +ATOM 1427 HZ1 LYS 151 18.050 -15.547 -18.498 1.00 0.00 H +ATOM 1428 HZ2 LYS 151 16.968 -16.085 -19.690 1.00 0.00 H +ATOM 1429 HZ3 LYS 151 18.013 -14.787 -20.016 1.00 0.00 H +ATOM 1430 C LYS 151 11.179 -12.064 -19.400 1.00 0.00 C +ATOM 1431 O LYS 151 10.562 -11.455 -18.518 1.00 0.00 O +ATOM 1432 N THR 152 10.854 -13.304 -19.801 1.00 0.00 N +ATOM 1433 H THR 152 11.363 -13.738 -20.520 1.00 0.00 H +ATOM 1434 CA THR 152 9.746 -14.094 -19.227 1.00 0.00 C +ATOM 1435 CB THR 152 9.026 -14.989 -20.325 1.00 0.00 C +ATOM 1436 OG1 THR 152 8.022 -15.810 -19.713 1.00 0.00 O +ATOM 1437 HG1 THR 152 7.345 -15.261 -19.310 1.00 0.00 H +ATOM 1438 CG2 THR 152 10.021 -15.872 -21.111 1.00 0.00 C +ATOM 1439 C THR 152 10.178 -14.912 -17.984 1.00 0.00 C +ATOM 1440 O THR 152 11.150 -15.678 -18.040 1.00 0.00 O +ATOM 1441 N GLY 153 9.471 -14.695 -16.870 1.00 0.00 N +ATOM 1442 H GLY 153 8.723 -14.058 -16.858 1.00 0.00 H +ATOM 1443 CA GLY 153 9.761 -15.381 -15.618 1.00 0.00 C +ATOM 1444 C GLY 153 10.141 -14.412 -14.511 1.00 0.00 C +ATOM 1445 O GLY 153 9.805 -13.224 -14.595 1.00 0.00 O +ATOM 1446 N ARG 154 10.853 -14.926 -13.494 1.00 0.00 N +ATOM 1447 H ARG 154 11.078 -15.880 -13.533 1.00 0.00 H +ATOM 1448 CA ARG 154 11.349 -14.201 -12.293 1.00 0.00 C +ATOM 1449 CB ARG 154 12.890 -13.963 -12.352 1.00 0.00 C +ATOM 1450 CG ARG 154 13.560 -13.633 -13.724 1.00 0.00 C +ATOM 1451 CD ARG 154 13.530 -12.142 -14.130 1.00 0.00 C +ATOM 1452 NE ARG 154 12.188 -11.700 -14.522 1.00 0.00 N +ATOM 1453 HE ARG 154 11.459 -11.827 -13.880 1.00 0.00 H +ATOM 1454 CZ ARG 154 11.873 -11.140 -15.691 1.00 0.00 C +ATOM 1455 NH1 ARG 154 10.618 -10.784 -15.927 1.00 0.00 N +ATOM 1456 HH11 ARG 154 9.916 -10.937 -15.232 1.00 0.00 H +ATOM 1457 HH12 ARG 154 10.374 -10.364 -16.801 1.00 0.00 H +ATOM 1458 NH2 ARG 154 12.795 -10.935 -16.627 1.00 0.00 N +ATOM 1459 HH21 ARG 154 13.744 -11.202 -16.462 1.00 0.00 H +ATOM 1460 HH22 ARG 154 12.537 -10.513 -17.495 1.00 0.00 H +ATOM 1461 C ARG 154 10.604 -12.931 -11.769 1.00 0.00 C +ATOM 1462 O ARG 154 11.121 -11.811 -11.904 1.00 0.00 O +ATOM 1463 N PRO 155 9.366 -13.089 -11.199 1.00 0.00 N +ATOM 1464 CD PRO 155 8.473 -14.268 -11.266 1.00 0.00 C +ATOM 1465 CA PRO 155 8.601 -11.935 -10.676 1.00 0.00 C +ATOM 1466 CB PRO 155 7.185 -12.505 -10.506 1.00 0.00 C +ATOM 1467 CG PRO 155 7.129 -13.631 -11.484 1.00 0.00 C +ATOM 1468 C PRO 155 9.122 -11.338 -9.348 1.00 0.00 C +ATOM 1469 O PRO 155 9.349 -12.076 -8.379 1.00 0.00 O +ATOM 1470 N LEU 156 9.322 -10.006 -9.342 1.00 0.00 N +ATOM 1471 H LEU 156 9.140 -9.491 -10.158 1.00 0.00 H +ATOM 1472 CA LEU 156 9.806 -9.176 -8.204 1.00 0.00 C +ATOM 1473 CB LEU 156 8.599 -8.654 -7.364 1.00 0.00 C +ATOM 1474 CG LEU 156 8.657 -7.490 -6.357 1.00 0.00 C +ATOM 1475 CD1 LEU 156 7.827 -6.311 -6.841 1.00 0.00 C +ATOM 1476 CD2 LEU 156 8.162 -7.962 -4.996 1.00 0.00 C +ATOM 1477 C LEU 156 10.901 -9.803 -7.298 1.00 0.00 C +ATOM 1478 O LEU 156 12.086 -9.480 -7.441 1.00 0.00 O +ATOM 1479 N ILE 157 10.473 -10.689 -6.387 1.00 0.00 N +ATOM 1480 H ILE 157 9.519 -10.916 -6.333 1.00 0.00 H +ATOM 1481 CA ILE 157 11.336 -11.386 -5.416 1.00 0.00 C +ATOM 1482 CB ILE 157 10.855 -11.113 -3.917 1.00 0.00 C +ATOM 1483 CG2 ILE 157 11.145 -9.669 -3.529 1.00 0.00 C +ATOM 1484 CG1 ILE 157 9.368 -11.445 -3.690 1.00 0.00 C +ATOM 1485 CD1 ILE 157 9.104 -12.779 -2.961 1.00 0.00 C +ATOM 1486 C ILE 157 11.435 -12.902 -5.711 1.00 0.00 C +ATOM 1487 O ILE 157 10.564 -13.448 -6.399 1.00 0.00 O +ATOM 1488 N GLU 158 12.488 -13.558 -5.200 1.00 0.00 N +ATOM 1489 H GLU 158 13.156 -13.079 -4.663 1.00 0.00 H +ATOM 1490 CA GLU 158 12.720 -15.003 -5.396 1.00 0.00 C +ATOM 1491 CB GLU 158 14.024 -15.253 -6.171 1.00 0.00 C +ATOM 1492 CG GLU 158 13.996 -14.809 -7.632 1.00 0.00 C +ATOM 1493 CD GLU 158 15.305 -15.076 -8.351 1.00 0.00 C +ATOM 1494 OE1 GLU 158 16.183 -14.187 -8.341 1.00 0.00 O +ATOM 1495 OE2 GLU 158 15.455 -16.173 -8.929 1.00 0.00 O +ATOM 1496 C GLU 158 12.729 -15.814 -4.093 1.00 0.00 C +ATOM 1497 O GLU 158 12.055 -16.847 -4.008 1.00 0.00 O +ATOM 1498 N GLY 159 13.486 -15.345 -3.094 1.00 0.00 N +ATOM 1499 H GLY 159 14.001 -14.515 -3.194 1.00 0.00 H +ATOM 1500 CA GLY 159 13.585 -16.035 -1.813 1.00 0.00 C +ATOM 1501 C GLY 159 13.185 -15.186 -0.623 1.00 0.00 C +ATOM 1502 O GLY 159 13.812 -15.274 0.440 1.00 0.00 O +ATOM 1503 N LYS 160 12.143 -14.369 -0.812 1.00 0.00 N +ATOM 1504 H LYS 160 11.701 -14.355 -1.688 1.00 0.00 H +ATOM 1505 CA LYS 160 11.605 -13.476 0.223 1.00 0.00 C +ATOM 1506 CB LYS 160 11.583 -12.017 -0.286 1.00 0.00 C +ATOM 1507 CG LYS 160 11.922 -10.916 0.747 1.00 0.00 C +ATOM 1508 CD LYS 160 10.683 -10.265 1.383 1.00 0.00 C +ATOM 1509 CE LYS 160 11.093 -9.241 2.418 1.00 0.00 C +ATOM 1510 NZ LYS 160 9.941 -8.715 3.196 1.00 0.00 N +ATOM 1511 HZ1 LYS 160 9.480 -9.500 3.698 1.00 0.00 H +ATOM 1512 HZ2 LYS 160 10.283 -8.018 3.887 1.00 0.00 H +ATOM 1513 HZ3 LYS 160 9.255 -8.265 2.564 1.00 0.00 H +ATOM 1514 C LYS 160 10.182 -13.928 0.595 1.00 0.00 C +ATOM 1515 O LYS 160 9.520 -14.607 -0.198 1.00 0.00 O +ATOM 1516 N SER 161 9.737 -13.544 1.800 1.00 0.00 N +ATOM 1517 H SER 161 10.308 -13.006 2.391 1.00 0.00 H +ATOM 1518 CA SER 161 8.407 -13.874 2.337 1.00 0.00 C +ATOM 1519 CB SER 161 8.548 -14.466 3.749 1.00 0.00 C +ATOM 1520 OG SER 161 9.315 -13.625 4.597 1.00 0.00 O +ATOM 1521 HG SER 161 10.213 -13.551 4.266 1.00 0.00 H +ATOM 1522 C SER 161 7.507 -12.629 2.385 1.00 0.00 C +ATOM 1523 O SER 161 7.946 -11.587 2.876 1.00 0.00 O +ATOM 1524 N ILE 162 6.298 -12.717 1.801 1.00 0.00 N +ATOM 1525 H ILE 162 6.029 -13.545 1.347 1.00 0.00 H +ATOM 1526 CA ILE 162 5.308 -11.611 1.791 1.00 0.00 C +ATOM 1527 CB ILE 162 5.132 -10.901 0.378 1.00 0.00 C +ATOM 1528 CG2 ILE 162 4.278 -9.603 0.530 1.00 0.00 C +ATOM 1529 CG1 ILE 162 6.492 -10.525 -0.232 1.00 0.00 C +ATOM 1530 CD1 ILE 162 6.521 -10.539 -1.755 1.00 0.00 C +ATOM 1531 C ILE 162 3.937 -12.103 2.307 1.00 0.00 C +ATOM 1532 O ILE 162 3.482 -13.193 1.937 1.00 0.00 O +ATOM 1533 N THR 163 3.310 -11.280 3.163 1.00 0.00 N +ATOM 1534 H THR 163 3.730 -10.432 3.427 1.00 0.00 H +ATOM 1535 CA THR 163 1.989 -11.533 3.777 1.00 0.00 C +ATOM 1536 CB THR 163 2.060 -11.743 5.361 1.00 0.00 C +ATOM 1537 OG1 THR 163 0.743 -11.981 5.878 1.00 0.00 O +ATOM 1538 HG1 THR 163 0.766 -12.006 6.834 1.00 0.00 H +ATOM 1539 CG2 THR 163 2.694 -10.567 6.100 1.00 0.00 C +ATOM 1540 C THR 163 0.957 -10.449 3.409 1.00 0.00 C +ATOM 1541 O THR 163 1.328 -9.295 3.175 1.00 0.00 O +ATOM 1542 N GLY 164 -0.313 -10.856 3.298 1.00 0.00 N +ATOM 1543 H GLY 164 -0.554 -11.801 3.418 1.00 0.00 H +ATOM 1544 CA GLY 164 -1.410 -9.941 2.996 1.00 0.00 C +ATOM 1545 C GLY 164 -2.169 -9.792 4.301 1.00 0.00 C +ATOM 1546 O GLY 164 -2.518 -10.799 4.921 1.00 0.00 O +ATOM 1547 N PHE 165 -2.473 -8.541 4.659 1.00 0.00 N +ATOM 1548 H PHE 165 -2.277 -7.811 4.033 1.00 0.00 H +ATOM 1549 CA PHE 165 -3.093 -8.162 5.939 1.00 0.00 C +ATOM 1550 CB PHE 165 -2.178 -7.096 6.595 1.00 0.00 C +ATOM 1551 CG PHE 165 -0.845 -6.886 5.880 1.00 0.00 C +ATOM 1552 CD1 PHE 165 -0.742 -5.961 4.829 1.00 0.00 C +ATOM 1553 CD2 PHE 165 0.306 -7.615 6.239 1.00 0.00 C +ATOM 1554 CE1 PHE 165 0.465 -5.761 4.147 1.00 0.00 C +ATOM 1555 CE2 PHE 165 1.526 -7.423 5.561 1.00 0.00 C +ATOM 1556 CZ PHE 165 1.600 -6.494 4.513 1.00 0.00 C +ATOM 1557 C PHE 165 -4.553 -7.678 5.967 1.00 0.00 C +ATOM 1558 O PHE 165 -5.321 -7.961 5.047 1.00 0.00 O +ATOM 1559 N THR 166 -4.910 -6.963 7.051 1.00 0.00 N +ATOM 1560 H THR 166 -4.248 -6.825 7.764 1.00 0.00 H +ATOM 1561 CA THR 166 -6.242 -6.380 7.333 1.00 0.00 C +ATOM 1562 CB THR 166 -6.180 -5.513 8.633 1.00 0.00 C +ATOM 1563 OG1 THR 166 -5.298 -6.132 9.578 1.00 0.00 O +ATOM 1564 HG1 THR 166 -5.598 -7.015 9.805 1.00 0.00 H +ATOM 1565 CG2 THR 166 -7.571 -5.360 9.277 1.00 0.00 C +ATOM 1566 C THR 166 -6.786 -5.546 6.149 1.00 0.00 C +ATOM 1567 O THR 166 -5.999 -5.031 5.346 1.00 0.00 O +ATOM 1568 N ASP 167 -8.128 -5.455 6.050 1.00 0.00 N +ATOM 1569 H ASP 167 -8.682 -5.886 6.738 1.00 0.00 H +ATOM 1570 CA ASP 167 -8.922 -4.759 4.996 1.00 0.00 C +ATOM 1571 CB ASP 167 -8.421 -3.322 4.693 1.00 0.00 C +ATOM 1572 CG ASP 167 -9.553 -2.359 4.332 1.00 0.00 C +ATOM 1573 OD1 ASP 167 -10.050 -1.656 5.239 1.00 0.00 O +ATOM 1574 OD2 ASP 167 -9.937 -2.298 3.143 1.00 0.00 O +ATOM 1575 C ASP 167 -8.951 -5.625 3.718 1.00 0.00 C +ATOM 1576 O ASP 167 -9.960 -5.654 3.004 1.00 0.00 O +ATOM 1577 N VAL 168 -7.827 -6.313 3.458 1.00 0.00 N +ATOM 1578 H VAL 168 -7.027 -6.224 4.008 1.00 0.00 H +ATOM 1579 CA VAL 168 -7.640 -7.238 2.325 1.00 0.00 C +ATOM 1580 CB VAL 168 -6.353 -6.897 1.458 1.00 0.00 C +ATOM 1581 CG1 VAL 168 -6.592 -5.630 0.650 1.00 0.00 C +ATOM 1582 CG2 VAL 168 -5.087 -6.739 2.317 1.00 0.00 C +ATOM 1583 C VAL 168 -7.611 -8.688 2.862 1.00 0.00 C +ATOM 1584 O VAL 168 -7.619 -9.652 2.090 1.00 0.00 O +ATOM 1585 N GLY 169 -7.640 -8.809 4.198 1.00 0.00 N +ATOM 1586 H GLY 169 -7.669 -8.014 4.774 1.00 0.00 H +ATOM 1587 CA GLY 169 -7.631 -10.095 4.896 1.00 0.00 C +ATOM 1588 C GLY 169 -8.896 -10.897 4.625 1.00 0.00 C +ATOM 1589 O GLY 169 -8.852 -12.129 4.516 1.00 0.00 O +ATOM 1590 N GLU 170 -10.015 -10.169 4.503 1.00 0.00 N +ATOM 1591 H GLU 170 -9.938 -9.198 4.619 1.00 0.00 H +ATOM 1592 CA GLU 170 -11.354 -10.717 4.214 1.00 0.00 C +ATOM 1593 CB GLU 170 -12.443 -9.629 4.365 1.00 0.00 C +ATOM 1594 CG GLU 170 -12.118 -8.226 3.793 1.00 0.00 C +ATOM 1595 CD GLU 170 -13.187 -7.195 4.106 1.00 0.00 C +ATOM 1596 OE1 GLU 170 -13.186 -6.651 5.231 1.00 0.00 O +ATOM 1597 OE2 GLU 170 -14.023 -6.920 3.221 1.00 0.00 O +ATOM 1598 C GLU 170 -11.415 -11.387 2.824 1.00 0.00 C +ATOM 1599 O GLU 170 -12.082 -12.415 2.656 1.00 0.00 O +ATOM 1600 N THR 171 -10.714 -10.781 1.852 1.00 0.00 N +ATOM 1601 H THR 171 -10.231 -9.951 2.067 1.00 0.00 H +ATOM 1602 CA THR 171 -10.602 -11.275 0.461 1.00 0.00 C +ATOM 1603 CB THR 171 -10.019 -10.193 -0.508 1.00 0.00 C +ATOM 1604 OG1 THR 171 -8.734 -9.758 -0.051 1.00 0.00 O +ATOM 1605 HG1 THR 171 -8.387 -9.096 -0.653 1.00 0.00 H +ATOM 1606 CG2 THR 171 -10.954 -8.991 -0.609 1.00 0.00 C +ATOM 1607 C THR 171 -9.749 -12.563 0.410 1.00 0.00 C +ATOM 1608 O THR 171 -10.045 -13.482 -0.366 1.00 0.00 O +ATOM 1609 N ILE 172 -8.712 -12.608 1.265 1.00 0.00 N +ATOM 1610 H ILE 172 -8.559 -11.832 1.851 1.00 0.00 H +ATOM 1611 CA ILE 172 -7.767 -13.742 1.412 1.00 0.00 C +ATOM 1612 CB ILE 172 -6.496 -13.338 2.263 1.00 0.00 C +ATOM 1613 CG2 ILE 172 -5.528 -14.545 2.431 1.00 0.00 C +ATOM 1614 CG1 ILE 172 -5.750 -12.176 1.585 1.00 0.00 C +ATOM 1615 CD1 ILE 172 -4.951 -11.258 2.529 1.00 0.00 C +ATOM 1616 C ILE 172 -8.491 -14.966 2.029 1.00 0.00 C +ATOM 1617 O ILE 172 -8.202 -16.110 1.655 1.00 0.00 O +ATOM 1618 N LEU 173 -9.420 -14.701 2.960 1.00 0.00 N +ATOM 1619 H LEU 173 -9.585 -13.768 3.229 1.00 0.00 H +ATOM 1620 CA LEU 173 -10.228 -15.731 3.648 1.00 0.00 C +ATOM 1621 CB LEU 173 -11.012 -15.127 4.832 1.00 0.00 C +ATOM 1622 CG LEU 173 -10.335 -14.661 6.137 1.00 0.00 C +ATOM 1623 CD1 LEU 173 -11.183 -13.565 6.757 1.00 0.00 C +ATOM 1624 CD2 LEU 173 -10.124 -15.804 7.151 1.00 0.00 C +ATOM 1625 C LEU 173 -11.195 -16.430 2.681 1.00 0.00 C +ATOM 1626 O LEU 173 -11.464 -17.627 2.823 1.00 0.00 O +ATOM 1627 N GLY 174 -11.716 -15.657 1.723 1.00 0.00 N +ATOM 1628 H GLY 174 -11.493 -14.702 1.659 1.00 0.00 H +ATOM 1629 CA GLY 174 -12.637 -16.174 0.721 1.00 0.00 C +ATOM 1630 C GLY 174 -12.234 -15.771 -0.688 1.00 0.00 C +ATOM 1631 O GLY 174 -12.794 -14.817 -1.238 1.00 0.00 O +ATOM 1632 N VAL 175 -11.267 -16.501 -1.263 1.00 0.00 N +ATOM 1633 H VAL 175 -10.875 -17.242 -0.752 1.00 0.00 H +ATOM 1634 CA VAL 175 -10.744 -16.271 -2.628 1.00 0.00 C +ATOM 1635 CB VAL 175 -9.192 -16.570 -2.726 1.00 0.00 C +ATOM 1636 CG1 VAL 175 -8.586 -15.948 -3.993 1.00 0.00 C +ATOM 1637 CG2 VAL 175 -8.455 -16.051 -1.501 1.00 0.00 C +ATOM 1638 C VAL 175 -11.534 -17.182 -3.599 1.00 0.00 C +ATOM 1639 O VAL 175 -12.091 -18.198 -3.167 1.00 0.00 O +ATOM 1640 N ASP 176 -11.568 -16.813 -4.889 1.00 0.00 N +ATOM 1641 H ASP 176 -11.085 -16.007 -5.176 1.00 0.00 H +ATOM 1642 CA ASP 176 -12.295 -17.554 -5.942 1.00 0.00 C +ATOM 1643 CB ASP 176 -12.495 -16.665 -7.194 1.00 0.00 C +ATOM 1644 CG ASP 176 -11.202 -15.990 -7.675 1.00 0.00 C +ATOM 1645 OD1 ASP 176 -10.492 -16.586 -8.514 1.00 0.00 O +ATOM 1646 OD2 ASP 176 -10.911 -14.861 -7.222 1.00 0.00 O +ATOM 1647 C ASP 176 -11.781 -18.955 -6.348 1.00 0.00 C +ATOM 1648 O ASP 176 -12.588 -19.881 -6.481 1.00 0.00 O +ATOM 1649 N SER 177 -10.470 -19.089 -6.598 1.00 0.00 N +ATOM 1650 H SER 177 -9.876 -18.310 -6.526 1.00 0.00 H +ATOM 1651 CA SER 177 -9.857 -20.377 -6.984 1.00 0.00 C +ATOM 1652 CB SER 177 -8.512 -20.131 -7.683 1.00 0.00 C +ATOM 1653 OG SER 177 -7.634 -19.370 -6.870 1.00 0.00 O +ATOM 1654 HG SER 177 -7.998 -18.496 -6.706 1.00 0.00 H +ATOM 1655 C SER 177 -9.693 -21.436 -5.868 1.00 0.00 C +ATOM 1656 O SER 177 -10.126 -22.582 -6.038 1.00 0.00 O +ATOM 1657 N ILE 178 -9.072 -21.036 -4.746 1.00 0.00 N +ATOM 1658 H ILE 178 -8.768 -20.102 -4.681 1.00 0.00 H +ATOM 1659 CA ILE 178 -8.814 -21.896 -3.569 1.00 0.00 C +ATOM 1660 CB ILE 178 -7.512 -21.401 -2.783 1.00 0.00 C +ATOM 1661 CG2 ILE 178 -7.749 -20.023 -2.109 1.00 0.00 C +ATOM 1662 CG1 ILE 178 -6.992 -22.481 -1.810 1.00 0.00 C +ATOM 1663 CD1 ILE 178 -5.465 -22.551 -1.667 1.00 0.00 C +ATOM 1664 C ILE 178 -10.014 -22.227 -2.629 1.00 0.00 C +ATOM 1665 O ILE 178 -10.213 -23.396 -2.274 1.00 0.00 O +ATOM 1666 N LEU 179 -10.784 -21.195 -2.253 1.00 0.00 N +ATOM 1667 H LEU 179 -10.601 -20.294 -2.597 1.00 0.00 H +ATOM 1668 CA LEU 179 -11.930 -21.312 -1.328 1.00 0.00 C +ATOM 1669 CB LEU 179 -11.753 -20.334 -0.139 1.00 0.00 C +ATOM 1670 CG LEU 179 -10.673 -20.594 0.929 1.00 0.00 C +ATOM 1671 CD1 LEU 179 -9.663 -19.446 0.963 1.00 0.00 C +ATOM 1672 CD2 LEU 179 -11.316 -20.772 2.306 1.00 0.00 C +ATOM 1673 C LEU 179 -13.319 -21.121 -1.963 1.00 0.00 C +ATOM 1674 O LEU 179 -14.333 -21.500 -1.360 1.00 0.00 O +ATOM 1675 N LYS 180 -13.352 -20.566 -3.187 1.00 0.00 N +ATOM 1676 H LYS 180 -12.509 -20.319 -3.626 1.00 0.00 H +ATOM 1677 CA LYS 180 -14.574 -20.273 -3.990 1.00 0.00 C +ATOM 1678 CB LYS 180 -15.318 -21.557 -4.431 1.00 0.00 C +ATOM 1679 CG LYS 180 -14.555 -22.424 -5.426 1.00 0.00 C +ATOM 1680 CD LYS 180 -15.355 -23.665 -5.808 1.00 0.00 C +ATOM 1681 CE LYS 180 -14.610 -24.548 -6.806 1.00 0.00 C +ATOM 1682 NZ LYS 180 -13.403 -25.213 -6.230 1.00 0.00 N +ATOM 1683 HZ1 LYS 180 -13.687 -25.818 -5.433 1.00 0.00 H +ATOM 1684 HZ2 LYS 180 -12.946 -25.795 -6.961 1.00 0.00 H +ATOM 1685 HZ3 LYS 180 -12.735 -24.490 -5.895 1.00 0.00 H +ATOM 1686 C LYS 180 -15.551 -19.243 -3.377 1.00 0.00 C +ATOM 1687 O LYS 180 -16.331 -19.569 -2.469 1.00 0.00 O +ATOM 1688 N ALA 181 -15.443 -17.992 -3.851 1.00 0.00 N +ATOM 1689 H ALA 181 -14.775 -17.781 -4.541 1.00 0.00 H +ATOM 1690 CA ALA 181 -16.270 -16.848 -3.417 1.00 0.00 C +ATOM 1691 CB ALA 181 -15.533 -16.032 -2.338 1.00 0.00 C +ATOM 1692 C ALA 181 -16.596 -15.960 -4.630 1.00 0.00 C +ATOM 1693 O ALA 181 -16.041 -16.175 -5.715 1.00 0.00 O +ATOM 1694 N LYS 182 -17.486 -14.973 -4.438 1.00 0.00 N +ATOM 1695 H LYS 182 -17.895 -14.840 -3.555 1.00 0.00 H +ATOM 1696 CA LYS 182 -17.914 -14.035 -5.496 1.00 0.00 C +ATOM 1697 CB LYS 182 -19.447 -13.885 -5.506 1.00 0.00 C +ATOM 1698 CG LYS 182 -20.207 -15.128 -5.959 1.00 0.00 C +ATOM 1699 CD LYS 182 -21.714 -14.893 -5.938 1.00 0.00 C +ATOM 1700 CE LYS 182 -22.496 -16.125 -6.388 1.00 0.00 C +ATOM 1701 NZ LYS 182 -22.419 -17.266 -5.427 1.00 0.00 N +ATOM 1702 HZ1 LYS 182 -22.971 -18.067 -5.795 1.00 0.00 H +ATOM 1703 HZ2 LYS 182 -22.807 -16.972 -4.508 1.00 0.00 H +ATOM 1704 HZ3 LYS 182 -21.427 -17.554 -5.309 1.00 0.00 H +ATOM 1705 C LYS 182 -17.237 -12.650 -5.415 1.00 0.00 C +ATOM 1706 O LYS 182 -17.441 -11.903 -4.448 1.00 0.00 O +ATOM 1707 N ASN 183 -16.427 -12.340 -6.444 1.00 0.00 N +ATOM 1708 H ASN 183 -16.305 -12.989 -7.172 1.00 0.00 H +ATOM 1709 CA ASN 183 -15.653 -11.081 -6.633 1.00 0.00 C +ATOM 1710 CB ASN 183 -16.500 -10.003 -7.354 1.00 0.00 C +ATOM 1711 CG ASN 183 -16.876 -10.399 -8.778 1.00 0.00 C +ATOM 1712 OD1 ASN 183 -16.153 -10.098 -9.730 1.00 0.00 O +ATOM 1713 ND2 ASN 183 -18.019 -11.062 -8.928 1.00 0.00 N +ATOM 1714 HD21 ASN 183 -18.275 -11.324 -9.837 1.00 0.00 H +ATOM 1715 HD22 ASN 183 -18.563 -11.266 -8.138 1.00 0.00 H +ATOM 1716 C ASN 183 -14.895 -10.471 -5.425 1.00 0.00 C +ATOM 1717 O ASN 183 -15.458 -9.675 -4.658 1.00 0.00 O +ATOM 1718 N LEU 184 -13.640 -10.911 -5.245 1.00 0.00 N +ATOM 1719 H LEU 184 -13.263 -11.588 -5.849 1.00 0.00 H +ATOM 1720 CA LEU 184 -12.726 -10.455 -4.174 1.00 0.00 C +ATOM 1721 CB LEU 184 -12.740 -11.429 -2.953 1.00 0.00 C +ATOM 1722 CG LEU 184 -13.842 -11.719 -1.891 1.00 0.00 C +ATOM 1723 CD1 LEU 184 -14.261 -10.472 -1.091 1.00 0.00 C +ATOM 1724 CD2 LEU 184 -15.066 -12.433 -2.470 1.00 0.00 C +ATOM 1725 C LEU 184 -11.295 -10.343 -4.735 1.00 0.00 C +ATOM 1726 O LEU 184 -11.053 -10.742 -5.881 1.00 0.00 O +ATOM 1727 N ALA 185 -10.366 -9.805 -3.928 1.00 0.00 N +ATOM 1728 H ALA 185 -10.616 -9.498 -3.031 1.00 0.00 H +ATOM 1729 CA ALA 185 -8.946 -9.624 -4.293 1.00 0.00 C +ATOM 1730 CB ALA 185 -8.349 -8.460 -3.513 1.00 0.00 C +ATOM 1731 C ALA 185 -8.122 -10.903 -4.053 1.00 0.00 C +ATOM 1732 O ALA 185 -8.355 -11.614 -3.067 1.00 0.00 O +ATOM 1733 N THR 186 -7.174 -11.176 -4.961 1.00 0.00 N +ATOM 1734 H THR 186 -7.024 -10.569 -5.718 1.00 0.00 H +ATOM 1735 CA THR 186 -6.297 -12.365 -4.919 1.00 0.00 C +ATOM 1736 CB THR 186 -6.264 -13.082 -6.317 1.00 0.00 C +ATOM 1737 OG1 THR 186 -5.882 -12.145 -7.333 1.00 0.00 O +ATOM 1738 HG1 THR 186 -6.534 -11.443 -7.405 1.00 0.00 H +ATOM 1739 CG2 THR 186 -7.626 -13.674 -6.662 1.00 0.00 C +ATOM 1740 C THR 186 -4.858 -12.053 -4.425 1.00 0.00 C +ATOM 1741 O THR 186 -3.885 -12.210 -5.175 1.00 0.00 O +ATOM 1742 N VAL 187 -4.743 -11.610 -3.163 1.00 0.00 N +ATOM 1743 H VAL 187 -5.560 -11.514 -2.623 1.00 0.00 H +ATOM 1744 CA VAL 187 -3.456 -11.256 -2.508 1.00 0.00 C +ATOM 1745 CB VAL 187 -3.694 -10.434 -1.167 1.00 0.00 C +ATOM 1746 CG1 VAL 187 -2.428 -9.670 -0.740 1.00 0.00 C +ATOM 1747 CG2 VAL 187 -4.868 -9.464 -1.314 1.00 0.00 C +ATOM 1748 C VAL 187 -2.568 -12.504 -2.225 1.00 0.00 C +ATOM 1749 O VAL 187 -1.373 -12.509 -2.561 1.00 0.00 O +ATOM 1750 N GLU 188 -3.175 -13.550 -1.643 1.00 0.00 N +ATOM 1751 H GLU 188 -4.131 -13.489 -1.425 1.00 0.00 H +ATOM 1752 CA GLU 188 -2.501 -14.818 -1.299 1.00 0.00 C +ATOM 1753 CB GLU 188 -3.387 -15.658 -0.359 1.00 0.00 C +ATOM 1754 CG GLU 188 -2.628 -16.581 0.616 1.00 0.00 C +ATOM 1755 CD GLU 188 -3.551 -17.413 1.492 1.00 0.00 C +ATOM 1756 OE1 GLU 188 -4.141 -18.394 0.989 1.00 0.00 O +ATOM 1757 OE2 GLU 188 -3.676 -17.093 2.693 1.00 0.00 O +ATOM 1758 C GLU 188 -2.129 -15.613 -2.568 1.00 0.00 C +ATOM 1759 O GLU 188 -1.053 -16.215 -2.624 1.00 0.00 O +ATOM 1760 N ASP 189 -3.009 -15.562 -3.580 1.00 0.00 N +ATOM 1761 H ASP 189 -3.830 -15.030 -3.478 1.00 0.00 H +ATOM 1762 CA ASP 189 -2.836 -16.257 -4.871 1.00 0.00 C +ATOM 1763 CB ASP 189 -4.146 -16.228 -5.677 1.00 0.00 C +ATOM 1764 CG ASP 189 -4.499 -17.583 -6.290 1.00 0.00 C +ATOM 1765 OD1 ASP 189 -5.214 -18.370 -5.631 1.00 0.00 O +ATOM 1766 OD2 ASP 189 -4.077 -17.854 -7.435 1.00 0.00 O +ATOM 1767 C ASP 189 -1.673 -15.685 -5.709 1.00 0.00 C +ATOM 1768 O ASP 189 -0.895 -16.459 -6.277 1.00 0.00 O +ATOM 1769 N VAL 190 -1.544 -14.347 -5.745 1.00 0.00 N +ATOM 1770 H VAL 190 -2.185 -13.783 -5.258 1.00 0.00 H +ATOM 1771 CA VAL 190 -0.465 -13.658 -6.490 1.00 0.00 C +ATOM 1772 CB VAL 190 -0.732 -12.113 -6.710 1.00 0.00 C +ATOM 1773 CG1 VAL 190 -1.917 -11.913 -7.645 1.00 0.00 C +ATOM 1774 CG2 VAL 190 -0.953 -11.359 -5.389 1.00 0.00 C +ATOM 1775 C VAL 190 0.917 -13.917 -5.852 1.00 0.00 C +ATOM 1776 O VAL 190 1.908 -14.100 -6.568 1.00 0.00 O +ATOM 1777 N ALA 191 0.955 -13.933 -4.510 1.00 0.00 N +ATOM 1778 H ALA 191 0.139 -13.732 -3.986 1.00 0.00 H +ATOM 1779 CA ALA 191 2.169 -14.208 -3.716 1.00 0.00 C +ATOM 1780 CB ALA 191 1.945 -13.841 -2.255 1.00 0.00 C +ATOM 1781 C ALA 191 2.585 -15.689 -3.850 1.00 0.00 C +ATOM 1782 O ALA 191 3.781 -16.000 -3.892 1.00 0.00 O +ATOM 1783 N LYS 192 1.577 -16.575 -3.908 1.00 0.00 N +ATOM 1784 H LYS 192 0.651 -16.246 -3.848 1.00 0.00 H +ATOM 1785 CA LYS 192 1.719 -18.042 -4.060 1.00 0.00 C +ATOM 1786 CB LYS 192 0.390 -18.756 -3.781 1.00 0.00 C +ATOM 1787 CG LYS 192 0.159 -19.188 -2.342 1.00 0.00 C +ATOM 1788 CD LYS 192 -0.973 -20.214 -2.287 1.00 0.00 C +ATOM 1789 CE LYS 192 -1.274 -20.685 -0.871 1.00 0.00 C +ATOM 1790 NZ LYS 192 -2.021 -19.671 -0.077 1.00 0.00 N +ATOM 1791 HZ1 LYS 192 -2.922 -19.457 -0.550 1.00 0.00 H +ATOM 1792 HZ2 LYS 192 -1.454 -18.802 -0.002 1.00 0.00 H +ATOM 1793 HZ3 LYS 192 -2.212 -20.046 0.873 1.00 0.00 H +ATOM 1794 C LYS 192 2.234 -18.517 -5.431 1.00 0.00 C +ATOM 1795 O LYS 192 2.985 -19.498 -5.500 1.00 0.00 O +ATOM 1796 N LYS 193 1.843 -17.803 -6.498 1.00 0.00 N +ATOM 1797 H LYS 193 1.273 -17.010 -6.363 1.00 0.00 H +ATOM 1798 CA LYS 193 2.188 -18.132 -7.900 1.00 0.00 C +ATOM 1799 CB LYS 193 1.515 -17.148 -8.867 1.00 0.00 C +ATOM 1800 CG LYS 193 0.045 -17.427 -9.142 1.00 0.00 C +ATOM 1801 CD LYS 193 -0.516 -16.442 -10.163 1.00 0.00 C +ATOM 1802 CE LYS 193 -1.995 -16.685 -10.449 1.00 0.00 C +ATOM 1803 NZ LYS 193 -2.886 -16.325 -9.306 1.00 0.00 N +ATOM 1804 HZ1 LYS 193 -2.631 -16.895 -8.475 1.00 0.00 H +ATOM 1805 HZ2 LYS 193 -3.875 -16.513 -9.566 1.00 0.00 H +ATOM 1806 HZ3 LYS 193 -2.772 -15.315 -9.083 1.00 0.00 H +ATOM 1807 C LYS 193 3.673 -18.260 -8.276 1.00 0.00 C +ATOM 1808 O LYS 193 4.023 -19.178 -9.028 1.00 0.00 O +ATOM 1809 N TYR 194 4.535 -17.373 -7.757 1.00 0.00 N +ATOM 1810 H TYR 194 4.220 -16.665 -7.155 1.00 0.00 H +ATOM 1811 CA TYR 194 5.978 -17.414 -8.058 1.00 0.00 C +ATOM 1812 CB TYR 194 6.476 -16.054 -8.630 1.00 0.00 C +ATOM 1813 CG TYR 194 6.398 -14.818 -7.727 1.00 0.00 C +ATOM 1814 CD1 TYR 194 5.230 -14.020 -7.668 1.00 0.00 C +ATOM 1815 CE1 TYR 194 5.181 -12.849 -6.865 1.00 0.00 C +ATOM 1816 CD2 TYR 194 7.515 -14.414 -6.959 1.00 0.00 C +ATOM 1817 CE2 TYR 194 7.473 -13.250 -6.158 1.00 0.00 C +ATOM 1818 CZ TYR 194 6.309 -12.475 -6.116 1.00 0.00 C +ATOM 1819 OH TYR 194 6.287 -11.340 -5.339 1.00 0.00 O +ATOM 1820 HH TYR 194 5.426 -10.929 -5.376 1.00 0.00 H +ATOM 1821 C TYR 194 6.873 -17.918 -6.910 1.00 0.00 C +ATOM 1822 O TYR 194 7.580 -18.918 -7.081 1.00 0.00 O +ATOM 1823 N GLY 195 6.838 -17.233 -5.761 1.00 0.00 N +ATOM 1824 H GLY 195 6.266 -16.441 -5.657 1.00 0.00 H +ATOM 1825 CA GLY 195 7.649 -17.636 -4.619 1.00 0.00 C +ATOM 1826 C GLY 195 7.760 -16.659 -3.462 1.00 0.00 C +ATOM 1827 O GLY 195 8.783 -15.976 -3.329 1.00 0.00 O +ATOM 1828 N ALA 196 6.708 -16.597 -2.635 1.00 0.00 N +ATOM 1829 H ALA 196 5.927 -17.160 -2.826 1.00 0.00 H +ATOM 1830 CA ALA 196 6.635 -15.734 -1.443 1.00 0.00 C +ATOM 1831 CB ALA 196 6.004 -14.369 -1.779 1.00 0.00 C +ATOM 1832 C ALA 196 5.823 -16.441 -0.349 1.00 0.00 C +ATOM 1833 O ALA 196 4.785 -17.049 -0.643 1.00 0.00 O +ATOM 1834 N LYS 197 6.311 -16.363 0.897 1.00 0.00 N +ATOM 1835 H LYS 197 7.143 -15.873 1.073 1.00 0.00 H +ATOM 1836 CA LYS 197 5.677 -16.981 2.080 1.00 0.00 C +ATOM 1837 CB LYS 197 6.737 -17.662 2.959 1.00 0.00 C +ATOM 1838 CG LYS 197 7.371 -18.908 2.348 1.00 0.00 C +ATOM 1839 CD LYS 197 8.408 -19.518 3.284 1.00 0.00 C +ATOM 1840 CE LYS 197 9.057 -20.767 2.691 1.00 0.00 C +ATOM 1841 NZ LYS 197 9.935 -20.484 1.516 1.00 0.00 N +ATOM 1842 HZ1 LYS 197 10.342 -21.375 1.165 1.00 0.00 H +ATOM 1843 HZ2 LYS 197 9.374 -20.038 0.763 1.00 0.00 H +ATOM 1844 HZ3 LYS 197 10.702 -19.843 1.803 1.00 0.00 H +ATOM 1845 C LYS 197 4.882 -15.949 2.903 1.00 0.00 C +ATOM 1846 O LYS 197 5.338 -14.813 3.074 1.00 0.00 O +ATOM 1847 N TYR 198 3.703 -16.351 3.397 1.00 0.00 N +ATOM 1848 H TYR 198 3.383 -17.266 3.243 1.00 0.00 H +ATOM 1849 CA TYR 198 2.817 -15.476 4.190 1.00 0.00 C +ATOM 1850 CB TYR 198 1.406 -15.378 3.534 1.00 0.00 C +ATOM 1851 CG TYR 198 0.673 -16.701 3.249 1.00 0.00 C +ATOM 1852 CD1 TYR 198 0.905 -17.426 2.053 1.00 0.00 C +ATOM 1853 CE1 TYR 198 0.226 -18.646 1.788 1.00 0.00 C +ATOM 1854 CD2 TYR 198 -0.261 -17.230 4.173 1.00 0.00 C +ATOM 1855 CE2 TYR 198 -0.945 -18.449 3.915 1.00 0.00 C +ATOM 1856 CZ TYR 198 -0.694 -19.147 2.723 1.00 0.00 C +ATOM 1857 OH TYR 198 -1.350 -20.330 2.469 1.00 0.00 O +ATOM 1858 HH TYR 198 -1.942 -20.546 3.194 1.00 0.00 H +ATOM 1859 C TYR 198 2.699 -15.829 5.684 1.00 0.00 C +ATOM 1860 O TYR 198 2.542 -17.002 6.043 1.00 0.00 O +ATOM 1861 N LEU 199 2.791 -14.793 6.530 1.00 0.00 N +ATOM 1862 H LEU 199 2.990 -13.903 6.194 1.00 0.00 H +ATOM 1863 CA LEU 199 2.687 -14.888 7.995 1.00 0.00 C +ATOM 1864 CB LEU 199 3.895 -14.174 8.653 1.00 0.00 C +ATOM 1865 CG LEU 199 4.474 -14.560 10.033 1.00 0.00 C +ATOM 1866 CD1 LEU 199 5.986 -14.410 9.995 1.00 0.00 C +ATOM 1867 CD2 LEU 199 3.878 -13.720 11.176 1.00 0.00 C +ATOM 1868 C LEU 199 1.353 -14.225 8.415 1.00 0.00 C +ATOM 1869 O LEU 199 1.244 -12.990 8.421 1.00 0.00 O +ATOM 1870 N ALA 200 0.342 -15.051 8.713 1.00 0.00 N +ATOM 1871 H ALA 200 0.458 -16.025 8.664 1.00 0.00 H +ATOM 1872 CA ALA 200 -0.985 -14.568 9.124 1.00 0.00 C +ATOM 1873 CB ALA 200 -2.066 -15.012 8.124 1.00 0.00 C +ATOM 1874 C ALA 200 -1.384 -14.948 10.565 1.00 0.00 C +ATOM 1875 O ALA 200 -1.295 -16.127 10.934 1.00 0.00 O +ATOM 1876 N PRO 201 -1.809 -13.952 11.404 1.00 0.00 N +ATOM 1877 CD PRO 201 -1.710 -12.503 11.115 1.00 0.00 C +ATOM 1878 CA PRO 201 -2.233 -14.132 12.809 1.00 0.00 C +ATOM 1879 CB PRO 201 -2.434 -12.678 13.286 1.00 0.00 C +ATOM 1880 CG PRO 201 -2.716 -11.913 12.049 1.00 0.00 C +ATOM 1881 C PRO 201 -3.489 -15.028 13.040 1.00 0.00 C +ATOM 1882 O PRO 201 -3.908 -15.743 12.122 1.00 0.00 O +ATOM 1883 N VAL 202 -4.066 -14.971 14.251 1.00 0.00 N +ATOM 1884 H VAL 202 -3.679 -14.368 14.926 1.00 0.00 H +ATOM 1885 CA VAL 202 -5.263 -15.747 14.646 1.00 0.00 C +ATOM 1886 CB VAL 202 -5.333 -15.902 16.236 1.00 0.00 C +ATOM 1887 CG1 VAL 202 -5.542 -14.548 16.947 1.00 0.00 C +ATOM 1888 CG2 VAL 202 -6.381 -16.945 16.661 1.00 0.00 C +ATOM 1889 C VAL 202 -6.554 -15.151 14.014 1.00 0.00 C +ATOM 1890 O VAL 202 -7.589 -15.825 13.927 1.00 0.00 O +ATOM 1891 N GLY 203 -6.437 -13.904 13.549 1.00 0.00 N +ATOM 1892 H GLY 203 -5.588 -13.414 13.619 1.00 0.00 H +ATOM 1893 CA GLY 203 -7.537 -13.190 12.916 1.00 0.00 C +ATOM 1894 C GLY 203 -6.970 -12.129 11.980 1.00 0.00 C +ATOM 1895 O GLY 203 -5.962 -11.521 12.357 1.00 0.00 O +ATOM 1896 N PRO 204 -7.544 -11.887 10.760 1.00 0.00 N +ATOM 1897 CD PRO 204 -8.554 -12.712 10.061 1.00 0.00 C +ATOM 1898 CA PRO 204 -7.022 -10.865 9.827 1.00 0.00 C +ATOM 1899 CB PRO 204 -7.783 -11.164 8.523 1.00 0.00 C +ATOM 1900 CG PRO 204 -8.102 -12.616 8.627 1.00 0.00 C +ATOM 1901 C PRO 204 -7.153 -9.378 10.261 1.00 0.00 C +ATOM 1902 O PRO 204 -7.631 -8.535 9.488 1.00 0.00 O +ATOM 1903 N TRP 205 -6.717 -9.077 11.495 1.00 0.00 N +ATOM 1904 H TRP 205 -6.333 -9.759 12.078 1.00 0.00 H +ATOM 1905 CA TRP 205 -6.761 -7.721 12.082 1.00 0.00 C +ATOM 1906 CB TRP 205 -8.028 -7.533 12.952 1.00 0.00 C +ATOM 1907 CG TRP 205 -9.385 -7.530 12.208 1.00 0.00 C +ATOM 1908 CD2 TRP 205 -10.248 -8.660 11.945 1.00 0.00 C +ATOM 1909 CE2 TRP 205 -11.400 -8.159 11.274 1.00 0.00 C +ATOM 1910 CE3 TRP 205 -10.163 -10.047 12.209 1.00 0.00 C +ATOM 1911 CD1 TRP 205 -10.041 -6.431 11.697 1.00 0.00 C +ATOM 1912 NE1 TRP 205 -11.240 -6.805 11.141 1.00 0.00 N +ATOM 1913 HE1 TRP 205 -11.877 -6.192 10.717 1.00 0.00 H +ATOM 1914 CZ2 TRP 205 -12.466 -8.994 10.860 1.00 0.00 C +ATOM 1915 CZ3 TRP 205 -11.228 -10.886 11.796 1.00 0.00 C +ATOM 1916 CH2 TRP 205 -12.364 -10.347 11.128 1.00 0.00 C +ATOM 1917 C TRP 205 -5.522 -7.342 12.914 1.00 0.00 C +ATOM 1918 O TRP 205 -4.869 -8.215 13.494 1.00 0.00 O +ATOM 1919 N ASP 206 -5.236 -6.027 12.963 1.00 0.00 N +ATOM 1920 H ASP 206 -5.803 -5.397 12.465 1.00 0.00 H +ATOM 1921 CA ASP 206 -4.128 -5.355 13.701 1.00 0.00 C +ATOM 1922 CB ASP 206 -4.486 -5.163 15.194 1.00 0.00 C +ATOM 1923 CG ASP 206 -5.666 -4.220 15.405 1.00 0.00 C +ATOM 1924 OD1 ASP 206 -6.820 -4.702 15.441 1.00 0.00 O +ATOM 1925 OD2 ASP 206 -5.440 -2.999 15.553 1.00 0.00 O +ATOM 1926 C ASP 206 -2.662 -5.828 13.583 1.00 0.00 C +ATOM 1927 O ASP 206 -1.778 -5.007 13.313 1.00 0.00 O +ATOM 1928 N ASP 207 -2.419 -7.132 13.784 1.00 0.00 N +ATOM 1929 H ASP 207 -3.165 -7.728 13.994 1.00 0.00 H +ATOM 1930 CA ASP 207 -1.076 -7.760 13.740 1.00 0.00 C +ATOM 1931 CB ASP 207 -1.173 -9.214 14.228 1.00 0.00 C +ATOM 1932 CG ASP 207 -1.545 -9.322 15.705 1.00 0.00 C +ATOM 1933 OD1 ASP 207 -0.626 -9.354 16.554 1.00 0.00 O +ATOM 1934 OD2 ASP 207 -2.754 -9.393 16.016 1.00 0.00 O +ATOM 1935 C ASP 207 -0.332 -7.688 12.385 1.00 0.00 C +ATOM 1936 O ASP 207 -0.114 -6.584 11.873 1.00 0.00 O +ATOM 1937 N TYR 208 0.079 -8.850 11.840 1.00 0.00 N +ATOM 1938 H TYR 208 -0.065 -9.715 12.271 1.00 0.00 H +ATOM 1939 CA TYR 208 0.791 -9.015 10.548 1.00 0.00 C +ATOM 1940 CB TYR 208 -0.125 -8.593 9.369 1.00 0.00 C +ATOM 1941 CG TYR 208 -1.250 -9.542 8.985 1.00 0.00 C +ATOM 1942 CD1 TYR 208 -2.564 -9.342 9.464 1.00 0.00 C +ATOM 1943 CE1 TYR 208 -3.630 -10.170 9.041 1.00 0.00 C +ATOM 1944 CD2 TYR 208 -1.032 -10.602 8.072 1.00 0.00 C +ATOM 1945 CE2 TYR 208 -2.094 -11.434 7.648 1.00 0.00 C +ATOM 1946 CZ TYR 208 -3.387 -11.212 8.134 1.00 0.00 C +ATOM 1947 OH TYR 208 -4.417 -12.024 7.715 1.00 0.00 O +ATOM 1948 HH TYR 208 -5.245 -11.744 8.104 1.00 0.00 H +ATOM 1949 C TYR 208 2.205 -8.395 10.404 1.00 0.00 C +ATOM 1950 O TYR 208 2.902 -8.216 11.409 1.00 0.00 O +ATOM 1951 N SER 209 2.609 -8.104 9.149 1.00 0.00 N +ATOM 1952 H SER 209 2.037 -8.293 8.377 1.00 0.00 H +ATOM 1953 CA SER 209 3.907 -7.516 8.715 1.00 0.00 C +ATOM 1954 CB SER 209 4.220 -6.181 9.414 1.00 0.00 C +ATOM 1955 OG SER 209 3.218 -5.214 9.146 1.00 0.00 O +ATOM 1956 HG SER 209 2.372 -5.495 9.505 1.00 0.00 H +ATOM 1957 C SER 209 5.116 -8.470 8.768 1.00 0.00 C +ATOM 1958 O SER 209 5.353 -9.128 9.790 1.00 0.00 O +ATOM 1959 N ILE 210 5.852 -8.534 7.648 1.00 0.00 N +ATOM 1960 H ILE 210 5.624 -7.974 6.874 1.00 0.00 H +ATOM 1961 CA ILE 210 7.032 -9.407 7.455 1.00 0.00 C +ATOM 1962 CB ILE 210 6.770 -10.515 6.333 1.00 0.00 C +ATOM 1963 CG2 ILE 210 6.014 -11.684 6.927 1.00 0.00 C +ATOM 1964 CG1 ILE 210 6.061 -9.949 5.079 1.00 0.00 C +ATOM 1965 CD1 ILE 210 6.963 -9.240 4.038 1.00 0.00 C +ATOM 1966 C ILE 210 8.356 -8.707 7.089 1.00 0.00 C +ATOM 1967 O ILE 210 8.346 -7.683 6.392 1.00 0.00 O +ATOM 1968 N THR 211 9.472 -9.226 7.623 1.00 0.00 N +ATOM 1969 H THR 211 9.419 -9.967 8.265 1.00 0.00 H +ATOM 1970 CA THR 211 10.826 -8.741 7.306 1.00 0.00 C +ATOM 1971 CB THR 211 11.453 -7.956 8.500 1.00 0.00 C +ATOM 1972 OG1 THR 211 10.416 -7.283 9.225 1.00 0.00 O +ATOM 1973 HG1 THR 211 9.809 -7.916 9.617 1.00 0.00 H +ATOM 1974 CG2 THR 211 12.453 -6.901 8.001 1.00 0.00 C +ATOM 1975 C THR 211 11.655 -10.007 6.977 1.00 0.00 C +ATOM 1976 O THR 211 11.688 -10.951 7.782 1.00 0.00 O +ATOM 1977 N ASP 212 12.248 -10.050 5.774 1.00 0.00 N +ATOM 1978 H ASP 212 12.136 -9.308 5.140 1.00 0.00 H +ATOM 1979 CA ASP 212 13.091 -11.176 5.316 1.00 0.00 C +ATOM 1980 CB ASP 212 12.322 -12.088 4.323 1.00 0.00 C +ATOM 1981 CG ASP 212 12.801 -13.542 4.348 1.00 0.00 C +ATOM 1982 OD1 ASP 212 12.247 -14.343 5.133 1.00 0.00 O +ATOM 1983 OD2 ASP 212 13.720 -13.884 3.571 1.00 0.00 O +ATOM 1984 C ASP 212 14.416 -10.674 4.707 1.00 0.00 C +ATOM 1985 O ASP 212 15.494 -11.024 5.199 1.00 0.00 O +ATOM 1986 N GLY 213 14.313 -9.862 3.648 1.00 0.00 N +ATOM 1987 H GLY 213 13.439 -9.597 3.296 1.00 0.00 H +ATOM 1988 CA GLY 213 15.480 -9.321 2.960 1.00 0.00 C +ATOM 1989 C GLY 213 15.505 -7.802 2.896 1.00 0.00 C +ATOM 1990 O GLY 213 15.684 -7.146 3.930 1.00 0.00 O +ATOM 1991 N ARG 214 15.326 -7.255 1.686 1.00 0.00 N +ATOM 1992 H ARG 214 15.186 -7.847 0.917 1.00 0.00 H +ATOM 1993 CA ARG 214 15.324 -5.802 1.426 1.00 0.00 C +ATOM 1994 CB ARG 214 16.111 -5.461 0.136 1.00 0.00 C +ATOM 1995 CG ARG 214 15.804 -6.311 -1.122 1.00 0.00 C +ATOM 1996 CD ARG 214 16.638 -5.881 -2.328 1.00 0.00 C +ATOM 1997 NE ARG 214 18.062 -6.198 -2.178 1.00 0.00 N +ATOM 1998 HE ARG 214 18.346 -6.644 -1.352 1.00 0.00 H +ATOM 1999 CZ ARG 214 19.009 -5.928 -3.077 1.00 0.00 C +ATOM 2000 NH1 ARG 214 20.266 -6.266 -2.825 1.00 0.00 N +ATOM 2001 HH11 ARG 214 20.498 -6.720 -1.965 1.00 0.00 H +ATOM 2002 HH12 ARG 214 20.981 -6.066 -3.495 1.00 0.00 H +ATOM 2003 NH2 ARG 214 18.715 -5.325 -4.226 1.00 0.00 N +ATOM 2004 HH21 ARG 214 17.771 -5.065 -4.427 1.00 0.00 H +ATOM 2005 HH22 ARG 214 19.439 -5.130 -4.888 1.00 0.00 H +ATOM 2006 C ARG 214 13.927 -5.145 1.413 1.00 0.00 C +ATOM 2007 O ARG 214 13.802 -3.951 1.718 1.00 0.00 O +ATOM 2008 N LEU 215 12.896 -5.937 1.082 1.00 0.00 N +ATOM 2009 H LEU 215 13.054 -6.882 0.862 1.00 0.00 H +ATOM 2010 CA LEU 215 11.492 -5.486 1.021 1.00 0.00 C +ATOM 2011 CB LEU 215 10.670 -6.396 0.050 1.00 0.00 C +ATOM 2012 CG LEU 215 9.157 -6.522 -0.325 1.00 0.00 C +ATOM 2013 CD1 LEU 215 8.380 -7.348 0.702 1.00 0.00 C +ATOM 2014 CD2 LEU 215 8.458 -5.182 -0.597 1.00 0.00 C +ATOM 2015 C LEU 215 10.847 -5.431 2.421 1.00 0.00 C +ATOM 2016 O LEU 215 11.122 -6.284 3.270 1.00 0.00 O +ATOM 2017 N VAL 216 10.058 -4.375 2.657 1.00 0.00 N +ATOM 2018 H VAL 216 9.932 -3.684 1.970 1.00 0.00 H +ATOM 2019 CA VAL 216 9.328 -4.149 3.919 1.00 0.00 C +ATOM 2020 CB VAL 216 9.787 -2.839 4.678 1.00 0.00 C +ATOM 2021 CG1 VAL 216 9.313 -2.854 6.143 1.00 0.00 C +ATOM 2022 CG2 VAL 216 11.309 -2.680 4.636 1.00 0.00 C +ATOM 2023 C VAL 216 7.850 -4.025 3.505 1.00 0.00 C +ATOM 2024 O VAL 216 7.550 -3.526 2.412 1.00 0.00 O +ATOM 2025 N THR 217 6.954 -4.564 4.340 1.00 0.00 N +ATOM 2026 H THR 217 7.246 -5.013 5.164 1.00 0.00 H +ATOM 2027 CA THR 217 5.501 -4.534 4.109 1.00 0.00 C +ATOM 2028 CB THR 217 4.926 -5.956 3.893 1.00 0.00 C +ATOM 2029 OG1 THR 217 5.383 -6.825 4.935 1.00 0.00 O +ATOM 2030 HG1 THR 217 4.960 -7.678 4.826 1.00 0.00 H +ATOM 2031 CG2 THR 217 5.321 -6.496 2.528 1.00 0.00 C +ATOM 2032 C THR 217 4.788 -3.850 5.283 1.00 0.00 C +ATOM 2033 O THR 217 5.430 -3.526 6.289 1.00 0.00 O +ATOM 2034 N GLY 218 3.475 -3.642 5.150 1.00 0.00 N +ATOM 2035 H GLY 218 2.989 -3.926 4.345 1.00 0.00 H +ATOM 2036 CA GLY 218 2.706 -2.986 6.193 1.00 0.00 C +ATOM 2037 C GLY 218 1.471 -3.692 6.700 1.00 0.00 C +ATOM 2038 O GLY 218 1.538 -4.874 7.039 1.00 0.00 O +ATOM 2039 N VAL 219 0.381 -2.924 6.861 1.00 0.00 N +ATOM 2040 H VAL 219 0.448 -1.970 6.642 1.00 0.00 H +ATOM 2041 CA VAL 219 -0.940 -3.392 7.348 1.00 0.00 C +ATOM 2042 CB VAL 219 -0.971 -3.706 8.897 1.00 0.00 C +ATOM 2043 CG1 VAL 219 -0.686 -5.146 9.154 1.00 0.00 C +ATOM 2044 CG2 VAL 219 0.039 -2.856 9.665 1.00 0.00 C +ATOM 2045 C VAL 219 -2.067 -2.378 7.076 1.00 0.00 C +ATOM 2046 O VAL 219 -3.207 -2.772 6.788 1.00 0.00 O +ATOM 2047 N ASN 220 -1.720 -1.084 7.142 1.00 0.00 N +ATOM 2048 H ASN 220 -0.778 -0.857 7.316 1.00 0.00 H +ATOM 2049 CA ASN 220 -2.644 0.053 6.969 1.00 0.00 C +ATOM 2050 CB ASN 220 -1.885 1.371 7.148 1.00 0.00 C +ATOM 2051 CG ASN 220 -2.608 2.351 8.076 1.00 0.00 C +ATOM 2052 OD1 ASN 220 -2.490 2.274 9.300 1.00 0.00 O +ATOM 2053 ND2 ASN 220 -3.365 3.269 7.489 1.00 0.00 N +ATOM 2054 HD21 ASN 220 -3.418 3.261 6.518 1.00 0.00 H +ATOM 2055 HD22 ASN 220 -3.837 3.915 8.055 1.00 0.00 H +ATOM 2056 C ASN 220 -3.542 0.104 5.702 1.00 0.00 C +ATOM 2057 O ASN 220 -3.035 -0.110 4.597 1.00 0.00 O +ATOM 2058 N PRO 221 -4.868 0.447 5.839 1.00 0.00 N +ATOM 2059 CD PRO 221 -5.624 0.536 4.573 1.00 0.00 C +ATOM 2060 CA PRO 221 -5.773 0.820 6.956 1.00 0.00 C +ATOM 2061 CB PRO 221 -7.100 1.108 6.239 1.00 0.00 C +ATOM 2062 CG PRO 221 -6.682 1.557 4.900 1.00 0.00 C +ATOM 2063 C PRO 221 -5.929 -0.192 8.129 1.00 0.00 C +ATOM 2064 O PRO 221 -6.863 -1.008 8.157 1.00 0.00 O +ATOM 2065 N ALA 222 -4.963 -0.133 9.061 1.00 0.00 N +ATOM 2066 H ALA 222 -4.247 0.533 8.985 1.00 0.00 H +ATOM 2067 CA ALA 222 -4.865 -0.971 10.276 1.00 0.00 C +ATOM 2068 CB ALA 222 -4.424 -2.422 9.935 1.00 0.00 C +ATOM 2069 C ALA 222 -3.864 -0.325 11.253 1.00 0.00 C +ATOM 2070 O ALA 222 -4.286 0.315 12.224 1.00 0.00 O +ATOM 2071 N SER 223 -2.554 -0.494 10.992 1.00 0.00 N +ATOM 2072 H SER 223 -2.274 -1.013 10.207 1.00 0.00 H +ATOM 2073 CA SER 223 -1.461 0.058 11.822 1.00 0.00 C +ATOM 2074 CB SER 223 -1.029 -0.946 12.913 1.00 0.00 C +ATOM 2075 OG SER 223 -0.683 -2.210 12.388 1.00 0.00 O +ATOM 2076 HG SER 223 0.178 -2.127 11.975 1.00 0.00 H +ATOM 2077 C SER 223 -0.239 0.574 11.023 1.00 0.00 C +ATOM 2078 O SER 223 0.709 -0.172 10.745 1.00 0.00 O +ATOM 2079 N ALA 224 -0.279 1.870 10.681 1.00 0.00 N +ATOM 2080 H ALA 224 -1.057 2.411 10.943 1.00 0.00 H +ATOM 2081 CA ALA 224 0.759 2.603 9.927 1.00 0.00 C +ATOM 2082 CB ALA 224 0.221 3.944 9.461 1.00 0.00 C +ATOM 2083 C ALA 224 2.071 2.788 10.708 1.00 0.00 C +ATOM 2084 O ALA 224 3.148 2.871 10.109 1.00 0.00 O +ATOM 2085 N HIS 225 1.949 2.922 12.036 1.00 0.00 N +ATOM 2086 H HIS 225 1.051 2.904 12.437 1.00 0.00 H +ATOM 2087 CA HIS 225 3.079 3.100 12.971 1.00 0.00 C +ATOM 2088 CB HIS 225 2.550 3.264 14.411 1.00 0.00 C +ATOM 2089 CG HIS 225 3.443 4.069 15.316 1.00 0.00 C +ATOM 2090 CD2 HIS 225 4.161 3.712 16.409 1.00 0.00 C +ATOM 2091 ND1 HIS 225 3.656 5.421 15.146 1.00 0.00 N +ATOM 2092 HD1 HIS 225 3.270 5.975 14.436 1.00 0.00 H +ATOM 2093 CE1 HIS 225 4.465 5.862 16.093 1.00 0.00 C +ATOM 2094 NE2 HIS 225 4.785 4.845 16.872 1.00 0.00 N +ATOM 2095 HE2 HIS 225 5.374 4.891 17.654 1.00 0.00 H +ATOM 2096 C HIS 225 4.072 1.917 12.885 1.00 0.00 C +ATOM 2097 O HIS 225 5.284 2.122 13.008 1.00 0.00 O +ATOM 2098 N SER 226 3.543 0.705 12.648 1.00 0.00 N +ATOM 2099 H SER 226 2.568 0.620 12.547 1.00 0.00 H +ATOM 2100 CA SER 226 4.328 -0.544 12.521 1.00 0.00 C +ATOM 2101 CB SER 226 3.390 -1.767 12.512 1.00 0.00 C +ATOM 2102 OG SER 226 4.113 -2.985 12.591 1.00 0.00 O +ATOM 2103 HG SER 226 3.499 -3.723 12.583 1.00 0.00 H +ATOM 2104 C SER 226 5.227 -0.544 11.261 1.00 0.00 C +ATOM 2105 O SER 226 6.417 -0.884 11.351 1.00 0.00 O +ATOM 2106 N THR 227 4.660 -0.135 10.114 1.00 0.00 N +ATOM 2107 H THR 227 3.715 0.136 10.118 1.00 0.00 H +ATOM 2108 CA THR 227 5.382 -0.059 8.824 1.00 0.00 C +ATOM 2109 CB THR 227 4.402 0.075 7.593 1.00 0.00 C +ATOM 2110 OG1 THR 227 5.149 0.035 6.369 1.00 0.00 O +ATOM 2111 HG1 THR 227 4.548 0.117 5.624 1.00 0.00 H +ATOM 2112 CG2 THR 227 3.572 1.365 7.643 1.00 0.00 C +ATOM 2113 C THR 227 6.448 1.059 8.813 1.00 0.00 C +ATOM 2114 O THR 227 7.561 0.856 8.314 1.00 0.00 O +ATOM 2115 N ALA 228 6.088 2.213 9.396 1.00 0.00 N +ATOM 2116 H ALA 228 5.192 2.304 9.794 1.00 0.00 H +ATOM 2117 CA ALA 228 6.952 3.401 9.493 1.00 0.00 C +ATOM 2118 CB ALA 228 6.139 4.607 9.928 1.00 0.00 C +ATOM 2119 C ALA 228 8.159 3.197 10.423 1.00 0.00 C +ATOM 2120 O ALA 228 9.258 3.667 10.107 1.00 0.00 O +ATOM 2121 N VAL 229 7.950 2.486 11.545 1.00 0.00 N +ATOM 2122 H VAL 229 7.046 2.146 11.739 1.00 0.00 H +ATOM 2123 CA VAL 229 9.013 2.179 12.528 1.00 0.00 C +ATOM 2124 CB VAL 229 8.416 1.729 13.936 1.00 0.00 C +ATOM 2125 CG1 VAL 229 7.776 0.334 13.883 1.00 0.00 C +ATOM 2126 CG2 VAL 229 9.465 1.837 15.054 1.00 0.00 C +ATOM 2127 C VAL 229 10.043 1.178 11.931 1.00 0.00 C +ATOM 2128 O VAL 229 11.255 1.347 12.114 1.00 0.00 O +ATOM 2129 N ARG 230 9.532 0.172 11.205 1.00 0.00 N +ATOM 2130 H ARG 230 8.550 0.092 11.111 1.00 0.00 H +ATOM 2131 CA ARG 230 10.336 -0.869 10.534 1.00 0.00 C +ATOM 2132 CB ARG 230 9.418 -2.014 10.043 1.00 0.00 C +ATOM 2133 CG ARG 230 10.059 -3.431 9.939 1.00 0.00 C +ATOM 2134 CD ARG 230 9.656 -4.391 11.079 1.00 0.00 C +ATOM 2135 NE ARG 230 8.230 -4.730 11.065 1.00 0.00 N +ATOM 2136 HE ARG 230 7.684 -4.372 10.334 1.00 0.00 H +ATOM 2137 CZ ARG 230 7.613 -5.490 11.971 1.00 0.00 C +ATOM 2138 NH1 ARG 230 6.314 -5.726 11.852 1.00 0.00 N +ATOM 2139 HH11 ARG 230 5.803 -5.335 11.086 1.00 0.00 H +ATOM 2140 HH12 ARG 230 5.845 -6.295 12.527 1.00 0.00 H +ATOM 2141 NH2 ARG 230 8.277 -6.017 12.995 1.00 0.00 N +ATOM 2142 HH21 ARG 230 9.258 -5.847 13.097 1.00 0.00 H +ATOM 2143 HH22 ARG 230 7.797 -6.584 13.664 1.00 0.00 H +ATOM 2144 C ARG 230 11.133 -0.254 9.359 1.00 0.00 C +ATOM 2145 O ARG 230 12.288 -0.633 9.122 1.00 0.00 O +ATOM 2146 N SER 231 10.506 0.708 8.662 1.00 0.00 N +ATOM 2147 H SER 231 9.591 0.968 8.917 1.00 0.00 H +ATOM 2148 CA SER 231 11.090 1.428 7.512 1.00 0.00 C +ATOM 2149 CB SER 231 10.007 2.227 6.773 1.00 0.00 C +ATOM 2150 OG SER 231 10.502 2.816 5.582 1.00 0.00 O +ATOM 2151 HG SER 231 9.799 3.307 5.151 1.00 0.00 H +ATOM 2152 C SER 231 12.260 2.346 7.919 1.00 0.00 C +ATOM 2153 O SER 231 13.312 2.314 7.271 1.00 0.00 O +ATOM 2154 N ILE 232 12.083 3.122 9.002 1.00 0.00 N +ATOM 2155 H ILE 232 11.228 3.093 9.487 1.00 0.00 H +ATOM 2156 CA ILE 232 13.121 4.042 9.524 1.00 0.00 C +ATOM 2157 CB ILE 232 12.562 5.129 10.536 1.00 0.00 C +ATOM 2158 CG2 ILE 232 11.633 6.094 9.796 1.00 0.00 C +ATOM 2159 CG1 ILE 232 11.853 4.501 11.751 1.00 0.00 C +ATOM 2160 CD1 ILE 232 12.372 4.971 13.113 1.00 0.00 C +ATOM 2161 C ILE 232 14.334 3.280 10.105 1.00 0.00 C +ATOM 2162 O ILE 232 15.478 3.726 9.959 1.00 0.00 O +ATOM 2163 N ASP 233 14.056 2.128 10.736 1.00 0.00 N +ATOM 2164 H ASP 233 13.115 1.842 10.834 1.00 0.00 H +ATOM 2165 CA ASP 233 15.073 1.237 11.334 1.00 0.00 C +ATOM 2166 CB ASP 233 14.389 0.127 12.158 1.00 0.00 C +ATOM 2167 CG ASP 233 15.280 -0.433 13.270 1.00 0.00 C +ATOM 2168 OD1 ASP 233 15.233 0.098 14.401 1.00 0.00 O +ATOM 2169 OD2 ASP 233 16.014 -1.413 13.014 1.00 0.00 O +ATOM 2170 C ASP 233 15.917 0.629 10.190 1.00 0.00 C +ATOM 2171 O ASP 233 17.132 0.453 10.339 1.00 0.00 O +ATOM 2172 N ALA 234 15.247 0.315 9.068 1.00 0.00 N +ATOM 2173 H ALA 234 14.269 0.435 9.029 1.00 0.00 H +ATOM 2174 CA ALA 234 15.864 -0.238 7.844 1.00 0.00 C +ATOM 2175 CB ALA 234 14.787 -0.766 6.896 1.00 0.00 C +ATOM 2176 C ALA 234 16.735 0.814 7.131 1.00 0.00 C +ATOM 2177 O ALA 234 17.811 0.485 6.618 1.00 0.00 O +ATOM 2178 N LEU 235 16.250 2.067 7.115 1.00 0.00 N +ATOM 2179 H LEU 235 15.381 2.253 7.537 1.00 0.00 H +ATOM 2180 CA LEU 235 16.928 3.231 6.502 1.00 0.00 C +ATOM 2181 CB LEU 235 15.964 4.434 6.384 1.00 0.00 C +ATOM 2182 CG LEU 235 14.864 4.486 5.306 1.00 0.00 C +ATOM 2183 CD1 LEU 235 13.636 5.169 5.886 1.00 0.00 C +ATOM 2184 CD2 LEU 235 15.323 5.211 4.027 1.00 0.00 C +ATOM 2185 C LEU 235 18.202 3.663 7.249 1.00 0.00 C +ATOM 2186 O LEU 235 19.218 3.963 6.613 1.00 0.00 O +ATOM 2187 N LYS 236 18.130 3.681 8.589 1.00 0.00 N +ATOM 2188 H LYS 236 17.289 3.423 9.029 1.00 0.00 H +ATOM 2189 CA LYS 236 19.241 4.063 9.487 1.00 0.00 C +ATOM 2190 CB LYS 236 18.730 4.293 10.917 1.00 0.00 C +ATOM 2191 CG LYS 236 17.902 5.558 11.101 1.00 0.00 C +ATOM 2192 CD LYS 236 17.456 5.719 12.546 1.00 0.00 C +ATOM 2193 CE LYS 236 16.648 6.992 12.735 1.00 0.00 C +ATOM 2194 NZ LYS 236 16.206 7.164 14.147 1.00 0.00 N +ATOM 2195 HZ1 LYS 236 15.612 6.357 14.424 1.00 0.00 H +ATOM 2196 HZ2 LYS 236 15.658 8.044 14.234 1.00 0.00 H +ATOM 2197 HZ3 LYS 236 17.039 7.211 14.768 1.00 0.00 H +ATOM 2198 C LYS 236 20.415 3.068 9.511 1.00 0.00 C +ATOM 2199 O LYS 236 21.577 3.486 9.561 1.00 0.00 O +ATOM 2200 N ASN 237 20.094 1.761 9.471 1.00 0.00 N +ATOM 2201 H ASN 237 19.147 1.501 9.429 1.00 0.00 H +ATOM 2202 CA ASN 237 21.043 0.611 9.483 1.00 0.00 C +ATOM 2203 CB ASN 237 21.885 0.567 8.177 1.00 0.00 C +ATOM 2204 CG ASN 237 22.270 -0.853 7.758 1.00 0.00 C +ATOM 2205 OD1 ASN 237 23.323 -1.364 8.146 1.00 0.00 O +ATOM 2206 ND2 ASN 237 21.421 -1.486 6.953 1.00 0.00 N +ATOM 2207 HD21 ASN 237 20.602 -1.029 6.666 1.00 0.00 H +ATOM 2208 HD22 ASN 237 21.653 -2.397 6.676 1.00 0.00 H +ATOM 2209 C ASN 237 21.943 0.532 10.748 1.00 0.00 C +ATOM 2210 O ASN 237 22.821 -0.338 10.838 1.00 0.00 O +ATOM 2211 N HIS 238 21.646 1.397 11.735 1.00 0.00 N +ATOM 2212 H HIS 238 20.887 2.010 11.629 1.00 0.00 H +ATOM 2213 CA HIS 238 22.342 1.547 13.045 1.00 0.00 C +ATOM 2214 CB HIS 238 21.633 0.747 14.181 1.00 0.00 C +ATOM 2215 CG HIS 238 21.448 -0.720 13.902 1.00 0.00 C +ATOM 2216 CD2 HIS 238 22.024 -1.814 14.458 1.00 0.00 C +ATOM 2217 ND1 HIS 238 20.562 -1.195 12.958 1.00 0.00 N +ATOM 2218 HD1 HIS 238 19.990 -0.645 12.384 1.00 0.00 H +ATOM 2219 CE1 HIS 238 20.599 -2.516 12.944 1.00 0.00 C +ATOM 2220 NE2 HIS 238 21.478 -2.916 13.845 1.00 0.00 N +ATOM 2221 HE2 HIS 238 21.705 -3.848 14.044 1.00 0.00 H +ATOM 2222 C HIS 238 23.883 1.391 13.124 1.00 0.00 C +ATOM 2223 O HIS 238 24.424 0.327 12.793 1.00 0.00 O +ATOM 2224 N HIS 239 24.558 2.465 13.557 1.00 0.00 N +ATOM 2225 H HIS 239 24.079 3.286 13.803 1.00 0.00 H +ATOM 2226 CA HIS 239 26.025 2.520 13.704 1.00 0.00 C +ATOM 2227 CB HIS 239 26.609 3.765 12.983 1.00 0.00 C +ATOM 2228 CG HIS 239 25.894 5.057 13.278 1.00 0.00 C +ATOM 2229 CD2 HIS 239 26.298 6.170 13.938 1.00 0.00 C +ATOM 2230 ND1 HIS 239 24.606 5.312 12.857 1.00 0.00 N +ATOM 2231 HD1 HIS 239 24.038 4.695 12.349 1.00 0.00 H +ATOM 2232 CE1 HIS 239 24.247 6.524 13.243 1.00 0.00 C +ATOM 2233 NE2 HIS 239 25.256 7.065 13.901 1.00 0.00 N +ATOM 2234 HE2 HIS 239 25.261 7.961 14.299 1.00 0.00 H +ATOM 2235 C HIS 239 26.490 2.462 15.173 1.00 0.00 C +ATOM 2236 O HIS 239 25.749 2.880 16.072 1.00 0.00 O +ATOM 2237 N HIS 240 27.708 1.946 15.393 1.00 0.00 N +ATOM 2238 H HIS 240 28.254 1.629 14.640 1.00 0.00 H +ATOM 2239 CA HIS 240 28.322 1.809 16.728 1.00 0.00 C +ATOM 2240 CB HIS 240 28.953 0.403 16.906 1.00 0.00 C +ATOM 2241 CG HIS 240 29.823 -0.048 15.763 1.00 0.00 C +ATOM 2242 CD2 HIS 240 31.157 -0.273 15.693 1.00 0.00 C +ATOM 2243 ND1 HIS 240 29.322 -0.339 14.512 1.00 0.00 N +ATOM 2244 HD1 HIS 240 28.381 -0.273 14.244 1.00 0.00 H +ATOM 2245 CE1 HIS 240 30.307 -0.723 13.720 1.00 0.00 C +ATOM 2246 NE2 HIS 240 31.431 -0.692 14.413 1.00 0.00 N +ATOM 2247 HE2 HIS 240 32.318 -0.929 14.069 1.00 0.00 H +ATOM 2248 C HIS 240 29.343 2.917 17.056 1.00 0.00 C +ATOM 2249 O HIS 240 30.070 3.373 16.164 1.00 0.00 O +ATOM 2250 N HIS 241 29.379 3.330 18.331 1.00 0.00 N +ATOM 2251 H HIS 241 28.778 2.932 18.998 1.00 0.00 H +ATOM 2252 CA HIS 241 30.285 4.379 18.837 1.00 0.00 C +ATOM 2253 CB HIS 241 29.507 5.429 19.673 1.00 0.00 C +ATOM 2254 CG HIS 241 28.574 4.849 20.703 1.00 0.00 C +ATOM 2255 CD2 HIS 241 27.222 4.867 20.793 1.00 0.00 C +ATOM 2256 ND1 HIS 241 29.020 4.168 21.817 1.00 0.00 N +ATOM 2257 HD1 HIS 241 29.957 3.988 22.039 1.00 0.00 H +ATOM 2258 CE1 HIS 241 27.985 3.791 22.547 1.00 0.00 C +ATOM 2259 NE2 HIS 241 26.883 4.203 21.948 1.00 0.00 N +ATOM 2260 HE2 HIS 241 25.970 4.059 22.274 1.00 0.00 H +ATOM 2261 C HIS 241 31.487 3.826 19.628 1.00 0.00 C +ATOM 2262 O HIS 241 31.368 2.788 20.289 1.00 0.00 O +ATOM 2263 N HIS 242 32.625 4.530 19.545 1.00 0.00 N +ATOM 2264 H HIS 242 32.664 5.349 19.004 1.00 0.00 H +ATOM 2265 CA HIS 242 33.880 4.162 20.229 1.00 0.00 C +ATOM 2266 CB HIS 242 35.065 4.191 19.241 1.00 0.00 C +ATOM 2267 CG HIS 242 34.978 3.171 18.142 1.00 0.00 C +ATOM 2268 CD2 HIS 242 34.815 3.313 16.803 1.00 0.00 C +ATOM 2269 ND1 HIS 242 35.084 1.815 18.369 1.00 0.00 N +ATOM 2270 HD1 HIS 242 35.211 1.390 19.244 1.00 0.00 H +ATOM 2271 CE1 HIS 242 34.990 1.166 17.222 1.00 0.00 C +ATOM 2272 NE2 HIS 242 34.826 2.052 16.257 1.00 0.00 N +ATOM 2273 HE2 HIS 242 34.728 1.845 15.304 1.00 0.00 H +ATOM 2274 C HIS 242 34.173 5.092 21.415 1.00 0.00 C +ATOM 2275 O HIS 242 33.807 6.273 21.381 1.00 0.00 O +ATOM 2276 N HIS 243 34.837 4.546 22.451 1.00 0.00 N +ATOM 2277 H HIS 243 35.101 3.600 22.407 1.00 0.00 H +ATOM 2278 CA HIS 243 35.239 5.229 23.713 1.00 0.00 C +ATOM 2279 CB HIS 243 36.357 6.276 23.476 1.00 0.00 C +ATOM 2280 CG HIS 243 37.650 5.695 22.979 1.00 0.00 C +ATOM 2281 CD2 HIS 243 38.289 5.827 21.790 1.00 0.00 C +ATOM 2282 ND1 HIS 243 38.452 4.883 23.753 1.00 0.00 N +ATOM 2283 HD1 HIS 243 38.261 4.601 24.672 1.00 0.00 H +ATOM 2284 CE1 HIS 243 39.527 4.540 23.066 1.00 0.00 C +ATOM 2285 NE2 HIS 243 39.452 5.099 21.872 1.00 0.00 N +ATOM 2286 HE2 HIS 243 40.118 5.010 21.159 1.00 0.00 H +ATOM 2287 C HIS 243 34.114 5.843 24.558 1.00 0.00 C +ATOM 2288 O HIS 243 33.200 6.471 23.981 1.00 0.00 O +ATOM 2289 OXT HIS 243 34.164 5.682 25.796 1.00 0.00 O +END diff --git a/examples/testdata/raptorxeg/models/195600_model_2.pdb b/examples/testdata/raptorxeg/models/195600_model_2.pdb new file mode 100644 index 0000000..12df18f --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600_model_2.pdb @@ -0,0 +1,2358 @@ +REMARK FILENAME="11_195600_10.pdb" +REMARK The macromolecule has 243 residues +REMARK Trial structure 10 of 10 structures +REMARK Molecular dynamics scheme : cartesian; cartesian; minimize +REMARK High temperature dynamics : +REMARK temp: 2000 steps: 1000 time(ps): 3 +REMARK 1st cooling stage : +REMARK temp: 2000->0 steps: 1000 time(ps): 5 temp step: 25 +REMARK 2nd cooling stage not used: +REMARK a total 36450 steps of minimization +REMARK VDW scale factors 20 20 0.01 0.003 0.003; 3E-03->4; 1 +REMARK 1073 NOEs in 3 class(es) with scale factors of 10; 10; 10 +REMARK averaging function(s): cent, sum, hbnd: cent +REMARK 0 3-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 1-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 carbon chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 proton chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 diffusion anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 susceptability anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 188 dihedral restraints with scale factors of 5; 50; 50 +REMARK 0 planarity restraints with a scale factor of NA +REMARK NCS restraints not used. +REMARK =============================================================== +REMARK bond, angles, improp, vdw(<1.6), dihed +REMARK violations : 33 183 28 11 313 +REMARK RMSD : 0.0203 3.911 4.548 23.695 +REMARK =============================================================== +REMARK noe, cdih, coup, oneb, carb-a, carb-b, +REMARK violations : 104 9 0 0 0 ----- +REMARK RMSD : 0.534 2.285 0.000 0.000 0.000 0.000 +REMARK 0.2/2 viol.: 245 43 0 +REMARK =============================================================== +REMARK dani, sani +REMARK violations : 0 0 +REMARK RMSD : 0.000 0.000 +REMARK .2/.1 viol.: 0 0 +REMARK =============================================================== +REMARK Protons violations, rmsd +REMARK all : 0 0.000 +REMARK class 1: 0 0.000 +REMARK class 2: 0 0.000 +REMARK class 3: 0 0.000 +REMARK class 4: 0 0.000 +REMARK =============================================================== +REMARK overall = 28043.9 +REMARK bon = 1042.83 +REMARK ang = 10240.6 +REMARK imp = 4947.1 +REMARK vdw = 8739.29 +REMARK harm = 0 +REMARK noe = 1408.15 +REMARK coup = 0 +REMARK oneb = 0 +REMARK carb = 0 +REMARK prot = 0 +REMARK dani = 0 +REMARK sani = 0 +REMARK cdih = 74.7456 +REMARK ncs = 0 +REMARK =============================================================== +REMARK DATE:15-Jan-2017 12:40:58 created by user: RaptorX +REMARK VERSION:1.3 +ATOM 1 CB MET 1 15.586 16.382 5.295 1.00 0.00 C +ATOM 2 CG MET 1 14.412 17.037 6.044 1.00 0.00 C +ATOM 3 SD MET 1 12.890 17.268 5.076 1.00 0.00 S +ATOM 4 CE MET 1 11.948 15.816 5.543 1.00 0.00 C +ATOM 5 C MET 1 17.521 16.610 3.696 1.00 0.00 C +ATOM 6 O MET 1 18.588 17.096 4.089 1.00 0.00 O +ATOM 7 HT1 MET 1 14.340 17.750 3.356 1.00 0.00 H +ATOM 8 HT2 MET 1 15.635 17.920 2.269 1.00 0.00 H +ATOM 9 N MET 1 15.227 17.326 3.019 1.00 0.00 N +ATOM 10 HT3 MET 1 15.036 16.375 2.648 1.00 0.00 H +ATOM 11 CA MET 1 16.190 17.218 4.154 1.00 0.00 C +ATOM 12 N ALA 2 17.446 15.560 2.856 1.00 0.00 N +ATOM 13 H ALA 2 16.564 15.229 2.577 1.00 0.00 H +ATOM 14 CA ALA 2 18.593 14.807 2.275 1.00 0.00 C +ATOM 15 CB ALA 2 19.351 15.668 1.233 1.00 0.00 C +ATOM 16 C ALA 2 19.595 14.170 3.281 1.00 0.00 C +ATOM 17 O ALA 2 19.826 14.753 4.346 1.00 0.00 O +ATOM 18 N PRO 3 20.189 12.968 2.976 1.00 0.00 N +ATOM 19 CD PRO 3 21.318 12.602 3.860 1.00 0.00 C +ATOM 20 CA PRO 3 20.140 12.005 1.847 1.00 0.00 C +ATOM 21 CB PRO 3 21.333 11.081 2.131 1.00 0.00 C +ATOM 22 CG PRO 3 22.269 11.934 2.901 1.00 0.00 C +ATOM 23 C PRO 3 18.833 11.186 1.738 1.00 0.00 C +ATOM 24 O PRO 3 17.912 11.380 2.540 1.00 0.00 O +ATOM 25 N LYS 4 18.778 10.279 0.744 1.00 0.00 N +ATOM 26 H LYS 4 19.548 10.184 0.141 1.00 0.00 H +ATOM 27 CA LYS 4 17.647 9.363 0.431 1.00 0.00 C +ATOM 28 CB LYS 4 17.485 8.259 1.499 1.00 0.00 C +ATOM 29 CG LYS 4 18.660 7.293 1.603 1.00 0.00 C +ATOM 30 CD LYS 4 18.438 6.269 2.710 1.00 0.00 C +ATOM 31 CE LYS 4 19.612 5.303 2.847 1.00 0.00 C +ATOM 32 NZ LYS 4 19.740 4.355 1.701 1.00 0.00 N +ATOM 33 HZ1 LYS 4 20.557 3.730 1.857 1.00 0.00 H +ATOM 34 HZ2 LYS 4 19.878 4.896 0.825 1.00 0.00 H +ATOM 35 HZ3 LYS 4 18.875 3.784 1.624 1.00 0.00 H +ATOM 36 C LYS 4 16.281 10.016 0.140 1.00 0.00 C +ATOM 37 O LYS 4 15.827 10.883 0.899 1.00 0.00 O +ATOM 38 N LYS 5 15.661 9.601 -0.974 1.00 0.00 N +ATOM 39 H LYS 5 16.078 8.926 -1.553 1.00 0.00 H +ATOM 40 CA LYS 5 14.346 10.094 -1.424 1.00 0.00 C +ATOM 41 CB LYS 5 14.462 10.849 -2.762 1.00 0.00 C +ATOM 42 CG LYS 5 15.225 12.168 -2.690 1.00 0.00 C +ATOM 43 CD LYS 5 15.290 12.843 -4.056 1.00 0.00 C +ATOM 44 CE LYS 5 16.052 14.166 -4.010 1.00 0.00 C +ATOM 45 NZ LYS 5 17.515 14.004 -3.757 1.00 0.00 N +ATOM 46 HZ1 LYS 5 17.658 13.532 -2.842 1.00 0.00 H +ATOM 47 HZ2 LYS 5 17.970 14.939 -3.740 1.00 0.00 H +ATOM 48 HZ3 LYS 5 17.936 13.427 -4.514 1.00 0.00 H +ATOM 49 C LYS 5 13.359 8.925 -1.568 1.00 0.00 C +ATOM 50 O LYS 5 13.679 7.913 -2.208 1.00 0.00 O +ATOM 51 N VAL 6 12.184 9.058 -0.932 1.00 0.00 N +ATOM 52 H VAL 6 11.987 9.863 -0.411 1.00 0.00 H +ATOM 53 CA VAL 6 11.109 8.047 -0.963 1.00 0.00 C +ATOM 54 CB VAL 6 10.740 7.517 0.507 1.00 0.00 C +ATOM 55 CG1 VAL 6 10.269 8.643 1.432 1.00 0.00 C +ATOM 56 CG2 VAL 6 9.729 6.359 0.465 1.00 0.00 C +ATOM 57 C VAL 6 9.893 8.557 -1.780 1.00 0.00 C +ATOM 58 O VAL 6 9.515 9.730 -1.666 1.00 0.00 O +ATOM 59 N LEU 7 9.306 7.658 -2.583 1.00 0.00 N +ATOM 60 H LEU 7 9.640 6.735 -2.620 1.00 0.00 H +ATOM 61 CA LEU 7 8.151 7.946 -3.455 1.00 0.00 C +ATOM 62 CB LEU 7 8.463 7.483 -4.899 1.00 0.00 C +ATOM 63 CG LEU 7 7.916 8.142 -6.183 1.00 0.00 C +ATOM 64 CD1 LEU 7 8.991 8.106 -7.255 1.00 0.00 C +ATOM 65 CD2 LEU 7 6.636 7.459 -6.685 1.00 0.00 C +ATOM 66 C LEU 7 6.881 7.248 -2.923 1.00 0.00 C +ATOM 67 O LEU 7 6.956 6.123 -2.413 1.00 0.00 O +ATOM 68 N LEU 8 5.738 7.940 -3.040 1.00 0.00 N +ATOM 69 H LEU 8 5.739 8.833 -3.449 1.00 0.00 H +ATOM 70 CA LEU 8 4.421 7.455 -2.589 1.00 0.00 C +ATOM 71 CB LEU 8 3.884 8.334 -1.433 1.00 0.00 C +ATOM 72 CG LEU 8 2.999 7.768 -0.300 1.00 0.00 C +ATOM 73 CD1 LEU 8 3.803 7.537 0.989 1.00 0.00 C +ATOM 74 CD2 LEU 8 1.862 8.741 -0.028 1.00 0.00 C +ATOM 75 C LEU 8 3.420 7.419 -3.762 1.00 0.00 C +ATOM 76 O LEU 8 3.479 8.273 -4.654 1.00 0.00 O +ATOM 77 N ALA 9 2.528 6.417 -3.748 1.00 0.00 N +ATOM 78 H ALA 9 2.538 5.755 -3.022 1.00 0.00 H +ATOM 79 CA ALA 9 1.489 6.214 -4.776 1.00 0.00 C +ATOM 80 CB ALA 9 1.516 4.773 -5.274 1.00 0.00 C +ATOM 81 C ALA 9 0.106 6.556 -4.194 1.00 0.00 C +ATOM 82 O ALA 9 -0.187 6.200 -3.044 1.00 0.00 O +ATOM 83 N LEU 10 -0.722 7.251 -4.989 1.00 0.00 N +ATOM 84 H LEU 10 -0.449 7.491 -5.902 1.00 0.00 H +ATOM 85 CA LEU 10 -2.070 7.701 -4.582 1.00 0.00 C +ATOM 86 CB LEU 10 -2.153 9.248 -4.610 1.00 0.00 C +ATOM 87 CG LEU 10 -1.004 10.247 -4.326 1.00 0.00 C +ATOM 88 CD1 LEU 10 -1.397 11.595 -4.906 1.00 0.00 C +ATOM 89 CD2 LEU 10 -0.632 10.397 -2.842 1.00 0.00 C +ATOM 90 C LEU 10 -3.205 7.128 -5.453 1.00 0.00 C +ATOM 91 O LEU 10 -2.988 6.823 -6.632 1.00 0.00 O +ATOM 92 N THR 11 -4.400 6.989 -4.853 1.00 0.00 N +ATOM 93 H THR 11 -4.499 7.230 -3.909 1.00 0.00 H +ATOM 94 CA THR 11 -5.630 6.480 -5.504 1.00 0.00 C +ATOM 95 OG1 THR 11 -6.147 5.365 -3.383 1.00 0.00 O +ATOM 96 HG1 THR 11 -6.681 6.118 -3.118 1.00 0.00 H +ATOM 97 CG2 THR 11 -5.330 3.985 -5.179 1.00 0.00 C +ATOM 98 C THR 11 -6.728 7.565 -5.495 1.00 0.00 C +ATOM 99 O THR 11 -6.668 8.485 -4.672 1.00 0.00 O +ATOM 100 CB THR 11 -6.170 5.194 -4.804 1.00 0.00 C +ATOM 101 N SER 12 -7.708 7.464 -6.409 1.00 0.00 N +ATOM 102 H SER 12 -7.715 6.716 -7.045 1.00 0.00 H +ATOM 103 CA SER 12 -8.812 8.438 -6.521 1.00 0.00 C +ATOM 104 CB SER 12 -8.829 9.079 -7.913 1.00 0.00 C +ATOM 105 OG SER 12 -9.018 8.114 -8.936 1.00 0.00 O +ATOM 106 HG SER 12 -9.875 7.689 -8.844 1.00 0.00 H +ATOM 107 C SER 12 -10.216 7.907 -6.185 1.00 0.00 C +ATOM 108 O SER 12 -10.960 8.574 -5.455 1.00 0.00 O +ATOM 109 N TYR 13 -10.566 6.724 -6.712 1.00 0.00 N +ATOM 110 H TYR 13 -9.924 6.236 -7.274 1.00 0.00 H +ATOM 111 CA TYR 13 -11.882 6.078 -6.501 1.00 0.00 C +ATOM 112 CB TYR 13 -12.059 4.872 -7.452 1.00 0.00 C +ATOM 113 CG TYR 13 -12.048 5.175 -8.956 1.00 0.00 C +ATOM 114 CD1 TYR 13 -13.249 5.458 -9.655 1.00 0.00 C +ATOM 115 CE1 TYR 13 -13.247 5.703 -11.056 1.00 0.00 C +ATOM 116 CD2 TYR 13 -10.842 5.144 -9.701 1.00 0.00 C +ATOM 117 CE2 TYR 13 -10.832 5.389 -11.102 1.00 0.00 C +ATOM 118 CZ TYR 13 -12.038 5.667 -11.767 1.00 0.00 C +ATOM 119 OH TYR 13 -12.035 5.905 -13.123 1.00 0.00 O +ATOM 120 HH TYR 13 -11.142 5.847 -13.471 1.00 0.00 H +ATOM 121 C TYR 13 -12.098 5.603 -5.062 1.00 0.00 C +ATOM 122 O TYR 13 -13.164 5.842 -4.482 1.00 0.00 O +ATOM 123 N ASN 14 -11.069 4.942 -4.506 1.00 0.00 N +ATOM 124 H ASN 14 -10.247 4.796 -5.025 1.00 0.00 H +ATOM 125 CA ASN 14 -11.019 4.379 -3.135 1.00 0.00 C +ATOM 126 CB ASN 14 -10.702 5.475 -2.091 1.00 0.00 C +ATOM 127 CG ASN 14 -9.503 6.338 -2.471 1.00 0.00 C +ATOM 128 OD1 ASN 14 -8.367 6.036 -2.114 1.00 0.00 O +ATOM 129 ND2 ASN 14 -9.763 7.437 -3.171 1.00 0.00 N +ATOM 130 HD21 ASN 14 -10.691 7.647 -3.409 1.00 0.00 H +ATOM 131 HD22 ASN 14 -9.004 8.003 -3.424 1.00 0.00 H +ATOM 132 C ASN 14 -12.260 3.530 -2.749 1.00 0.00 C +ATOM 133 O ASN 14 -12.911 3.777 -1.722 1.00 0.00 O +ATOM 134 N ASP 15 -12.560 2.533 -3.600 1.00 0.00 N +ATOM 135 H ASP 15 -11.988 2.396 -4.387 1.00 0.00 H +ATOM 136 CA ASP 15 -13.701 1.596 -3.464 1.00 0.00 C +ATOM 137 CB ASP 15 -13.704 0.587 -4.624 1.00 0.00 C +ATOM 138 CG ASP 15 -14.119 1.205 -5.951 1.00 0.00 C +ATOM 139 OD1 ASP 15 -13.287 1.879 -6.601 1.00 0.00 O +ATOM 140 OD2 ASP 15 -15.278 0.989 -6.360 1.00 0.00 O +ATOM 141 C ASP 15 -13.774 0.839 -2.127 1.00 0.00 C +ATOM 142 O ASP 15 -12.736 0.557 -1.520 1.00 0.00 O +ATOM 143 N VAL 16 -15.001 0.525 -1.689 1.00 0.00 N +ATOM 144 H VAL 16 -15.794 0.764 -2.218 1.00 0.00 H +ATOM 145 CA VAL 16 -15.269 -0.183 -0.422 1.00 0.00 C +ATOM 146 CB VAL 16 -16.497 0.444 0.355 1.00 0.00 C +ATOM 147 CG1 VAL 16 -16.116 1.802 0.930 1.00 0.00 C +ATOM 148 CG2 VAL 16 -17.738 0.581 -0.551 1.00 0.00 C +ATOM 149 C VAL 16 -15.383 -1.726 -0.526 1.00 0.00 C +ATOM 150 O VAL 16 -14.545 -2.438 0.041 1.00 0.00 O +ATOM 151 N PHE 17 -16.407 -2.220 -1.243 1.00 0.00 N +ATOM 152 H PHE 17 -17.040 -1.608 -1.676 1.00 0.00 H +ATOM 153 CA PHE 17 -16.663 -3.662 -1.438 1.00 0.00 C +ATOM 154 CB PHE 17 -17.824 -4.153 -0.526 1.00 0.00 C +ATOM 155 CG PHE 17 -17.535 -4.087 0.973 1.00 0.00 C +ATOM 156 CD1 PHE 17 -16.960 -5.190 1.650 1.00 0.00 C +ATOM 157 CD2 PHE 17 -17.871 -2.936 1.726 1.00 0.00 C +ATOM 158 CE1 PHE 17 -16.724 -5.151 3.053 1.00 0.00 C +ATOM 159 CE2 PHE 17 -17.641 -2.882 3.129 1.00 0.00 C +ATOM 160 CZ PHE 17 -17.066 -3.993 3.793 1.00 0.00 C +ATOM 161 C PHE 17 -16.999 -4.002 -2.897 1.00 0.00 C +ATOM 162 O PHE 17 -16.548 -5.035 -3.408 1.00 0.00 O +ATOM 163 N TYR 18 -17.783 -3.131 -3.549 1.00 0.00 N +ATOM 164 H TYR 18 -18.102 -2.318 -3.098 1.00 0.00 H +ATOM 165 CA TYR 18 -18.225 -3.299 -4.946 1.00 0.00 C +ATOM 166 CB TYR 18 -19.713 -2.889 -5.086 1.00 0.00 C +ATOM 167 CG TYR 18 -20.732 -3.708 -4.285 1.00 0.00 C +ATOM 168 CD1 TYR 18 -21.354 -4.852 -4.844 1.00 0.00 C +ATOM 169 CE1 TYR 18 -22.327 -5.594 -4.118 1.00 0.00 C +ATOM 170 CD2 TYR 18 -21.111 -3.325 -2.974 1.00 0.00 C +ATOM 171 CE2 TYR 18 -22.083 -4.061 -2.241 1.00 0.00 C +ATOM 172 CZ TYR 18 -22.683 -5.191 -2.821 1.00 0.00 C +ATOM 173 OH TYR 18 -23.624 -5.907 -2.117 1.00 0.00 O +ATOM 174 HH TYR 18 -23.764 -5.515 -1.252 1.00 0.00 H +ATOM 175 C TYR 18 -17.371 -2.518 -5.960 1.00 0.00 C +ATOM 176 O TYR 18 -16.714 -1.537 -5.592 1.00 0.00 O +ATOM 177 N SER 19 -17.395 -2.968 -7.224 1.00 0.00 N +ATOM 178 H SER 19 -17.934 -3.756 -7.458 1.00 0.00 H +ATOM 179 CA SER 19 -16.653 -2.360 -8.343 1.00 0.00 C +ATOM 180 CB SER 19 -16.101 -3.455 -9.268 1.00 0.00 C +ATOM 181 OG SER 19 -17.123 -4.338 -9.701 1.00 0.00 O +ATOM 182 HG SER 19 -17.505 -4.805 -8.953 1.00 0.00 H +ATOM 183 C SER 19 -17.527 -1.375 -9.143 1.00 0.00 C +ATOM 184 O SER 19 -17.005 -0.431 -9.750 1.00 0.00 O +ATOM 185 N ASP 20 -18.848 -1.603 -9.114 1.00 0.00 N +ATOM 186 H ASP 20 -19.210 -2.366 -8.610 1.00 0.00 H +ATOM 187 CA ASP 20 -19.850 -0.769 -9.806 1.00 0.00 C +ATOM 188 CB ASP 20 -20.892 -1.646 -10.547 1.00 0.00 C +ATOM 189 CG ASP 20 -21.465 -2.777 -9.681 1.00 0.00 C +ATOM 190 OD1 ASP 20 -20.892 -3.888 -9.690 1.00 0.00 O +ATOM 191 OD2 ASP 20 -22.495 -2.553 -9.007 1.00 0.00 O +ATOM 192 C ASP 20 -20.527 0.249 -8.866 1.00 0.00 C +ATOM 193 O ASP 20 -21.097 -0.130 -7.835 1.00 0.00 O +ATOM 194 N GLY 21 -20.420 1.534 -9.224 1.00 0.00 N +ATOM 195 H GLY 21 -19.945 1.796 -10.043 1.00 0.00 H +ATOM 196 CA GLY 21 -20.994 2.617 -8.432 1.00 0.00 C +ATOM 197 C GLY 21 -19.914 3.413 -7.722 1.00 0.00 C +ATOM 198 O GLY 21 -19.931 4.649 -7.737 1.00 0.00 O +ATOM 199 N ALA 22 -18.970 2.677 -7.114 1.00 0.00 N +ATOM 200 H ALA 22 -19.047 1.700 -7.162 1.00 0.00 H +ATOM 201 CA ALA 22 -17.799 3.179 -6.360 1.00 0.00 C +ATOM 202 CB ALA 22 -16.673 3.624 -7.319 1.00 0.00 C +ATOM 203 C ALA 22 -18.008 4.239 -5.265 1.00 0.00 C +ATOM 204 O ALA 22 -18.652 5.270 -5.498 1.00 0.00 O +ATOM 205 N LYS 23 -17.457 3.952 -4.078 1.00 0.00 N +ATOM 206 H LYS 23 -16.981 3.102 -3.944 1.00 0.00 H +ATOM 207 CA LYS 23 -17.496 4.829 -2.893 1.00 0.00 C +ATOM 208 CB LYS 23 -18.112 4.101 -1.690 1.00 0.00 C +ATOM 209 CG LYS 23 -19.619 3.886 -1.799 1.00 0.00 C +ATOM 210 CD LYS 23 -20.206 3.324 -0.509 1.00 0.00 C +ATOM 211 CE LYS 23 -21.709 3.080 -0.621 1.00 0.00 C +ATOM 212 NZ LYS 23 -22.513 4.336 -0.716 1.00 0.00 N +ATOM 213 HZ1 LYS 23 -22.221 4.872 -1.558 1.00 0.00 H +ATOM 214 HZ2 LYS 23 -22.356 4.915 0.134 1.00 0.00 H +ATOM 215 HZ3 LYS 23 -23.522 4.097 -0.790 1.00 0.00 H +ATOM 216 C LYS 23 -16.044 5.228 -2.595 1.00 0.00 C +ATOM 217 O LYS 23 -15.124 4.536 -3.038 1.00 0.00 O +ATOM 218 N THR 24 -15.842 6.342 -1.878 1.00 0.00 N +ATOM 219 H THR 24 -16.604 6.866 -1.546 1.00 0.00 H +ATOM 220 CA THR 24 -14.496 6.848 -1.544 1.00 0.00 C +ATOM 221 CB THR 24 -14.348 8.361 -1.894 1.00 0.00 C +ATOM 222 OG1 THR 24 -15.423 9.101 -1.302 1.00 0.00 O +ATOM 223 HG1 THR 24 -16.267 8.826 -1.672 1.00 0.00 H +ATOM 224 CG2 THR 24 -14.353 8.576 -3.404 1.00 0.00 C +ATOM 225 C THR 24 -14.019 6.599 -0.100 1.00 0.00 C +ATOM 226 O THR 24 -14.832 6.423 0.813 1.00 0.00 O +ATOM 227 N GLY 25 -12.692 6.587 0.063 1.00 0.00 N +ATOM 228 H GLY 25 -12.113 6.788 -0.696 1.00 0.00 H +ATOM 229 CA GLY 25 -12.019 6.372 1.338 1.00 0.00 C +ATOM 230 C GLY 25 -10.628 6.963 1.212 1.00 0.00 C +ATOM 231 O GLY 25 -10.370 7.627 0.200 1.00 0.00 O +ATOM 232 N VAL 26 -9.743 6.773 2.206 1.00 0.00 N +ATOM 233 H VAL 26 -10.009 6.257 2.995 1.00 0.00 H +ATOM 234 CA VAL 26 -8.378 7.331 2.124 1.00 0.00 C +ATOM 235 CB VAL 26 -8.358 8.894 2.413 1.00 0.00 C +ATOM 236 CG1 VAL 26 -8.333 9.191 3.919 1.00 0.00 C +ATOM 237 CG2 VAL 26 -7.245 9.599 1.632 1.00 0.00 C +ATOM 238 C VAL 26 -7.160 6.653 2.809 1.00 0.00 C +ATOM 239 O VAL 26 -7.203 6.219 3.967 1.00 0.00 O +ATOM 240 N PHE 27 -6.115 6.558 1.983 1.00 0.00 N +ATOM 241 H PHE 27 -6.281 6.864 1.072 1.00 0.00 H +ATOM 242 CA PHE 27 -4.748 6.071 2.219 1.00 0.00 C +ATOM 243 CG PHE 27 -4.216 6.913 -0.175 1.00 0.00 C +ATOM 244 CD1 PHE 27 -3.238 7.927 -0.289 1.00 0.00 C +ATOM 245 CD2 PHE 27 -5.363 6.990 -0.997 1.00 0.00 C +ATOM 246 CE1 PHE 27 -3.406 8.999 -1.196 1.00 0.00 C +ATOM 247 CE2 PHE 27 -5.542 8.055 -1.906 1.00 0.00 C +ATOM 248 CZ PHE 27 -4.564 9.063 -2.005 1.00 0.00 C +ATOM 249 C PHE 27 -3.901 7.065 3.044 1.00 0.00 C +ATOM 250 O PHE 27 -2.936 6.668 3.699 1.00 0.00 O +ATOM 251 CB PHE 27 -4.065 5.788 0.856 1.00 0.00 C +ATOM 252 N VAL 28 -4.256 8.360 2.955 1.00 0.00 N +ATOM 253 H VAL 28 -5.065 8.589 2.444 1.00 0.00 H +ATOM 254 CA VAL 28 -3.512 9.480 3.579 1.00 0.00 C +ATOM 255 CB VAL 28 -4.232 10.879 3.324 1.00 0.00 C +ATOM 256 CG1 VAL 28 -5.366 11.155 4.327 1.00 0.00 C +ATOM 257 CG2 VAL 28 -3.215 12.031 3.280 1.00 0.00 C +ATOM 258 C VAL 28 -3.150 9.287 5.070 1.00 0.00 C +ATOM 259 O VAL 28 -2.070 9.709 5.475 1.00 0.00 O +ATOM 260 N VAL 29 -4.015 8.626 5.847 1.00 0.00 N +ATOM 261 H VAL 29 -4.856 8.301 5.453 1.00 0.00 H +ATOM 262 CA VAL 29 -3.763 8.348 7.278 1.00 0.00 C +ATOM 263 CB VAL 29 -5.111 7.954 8.030 1.00 0.00 C +ATOM 264 CG1 VAL 29 -5.899 6.881 7.267 1.00 0.00 C +ATOM 265 CG2 VAL 29 -4.866 7.560 9.499 1.00 0.00 C +ATOM 266 C VAL 29 -2.586 7.341 7.460 1.00 0.00 C +ATOM 267 O VAL 29 -1.670 7.603 8.257 1.00 0.00 O +ATOM 268 N GLU 30 -2.593 6.248 6.675 1.00 0.00 N +ATOM 269 H GLU 30 -3.332 6.094 6.047 1.00 0.00 H +ATOM 270 CA GLU 30 -1.522 5.228 6.702 1.00 0.00 C +ATOM 271 CB GLU 30 -1.920 3.902 5.989 1.00 0.00 C +ATOM 272 CG GLU 30 -2.456 3.978 4.548 1.00 0.00 C +ATOM 273 CD GLU 30 -2.998 2.654 4.039 1.00 0.00 C +ATOM 274 OE1 GLU 30 -2.199 1.814 3.576 1.00 0.00 O +ATOM 275 OE2 GLU 30 -4.230 2.458 4.090 1.00 0.00 O +ATOM 276 C GLU 30 -0.235 5.851 6.136 1.00 0.00 C +ATOM 277 O GLU 30 0.853 5.586 6.641 1.00 0.00 O +ATOM 278 N ALA 31 -0.403 6.717 5.125 1.00 0.00 N +ATOM 279 H ALA 31 -1.304 6.896 4.783 1.00 0.00 H +ATOM 280 CA ALA 31 0.682 7.464 4.458 1.00 0.00 C +ATOM 281 CB ALA 31 0.160 8.129 3.186 1.00 0.00 C +ATOM 282 C ALA 31 1.283 8.519 5.406 1.00 0.00 C +ATOM 283 O ALA 31 2.502 8.714 5.416 1.00 0.00 O +ATOM 284 N LEU 32 0.417 9.134 6.232 1.00 0.00 N +ATOM 285 H LEU 32 -0.527 8.876 6.213 1.00 0.00 H +ATOM 286 CA LEU 32 0.781 10.169 7.226 1.00 0.00 C +ATOM 287 CB LEU 32 -0.471 10.832 7.845 1.00 0.00 C +ATOM 288 CG LEU 32 -0.988 12.189 7.328 1.00 0.00 C +ATOM 289 CD1 LEU 32 -2.506 12.195 7.386 1.00 0.00 C +ATOM 290 CD2 LEU 32 -0.420 13.380 8.121 1.00 0.00 C +ATOM 291 C LEU 32 1.688 9.626 8.336 1.00 0.00 C +ATOM 292 O LEU 32 2.602 10.335 8.773 1.00 0.00 O +ATOM 293 N HIS 33 1.452 8.371 8.761 1.00 0.00 N +ATOM 294 H HIS 33 0.689 7.856 8.400 1.00 0.00 H +ATOM 295 CA HIS 33 2.275 7.721 9.801 1.00 0.00 C +ATOM 296 CB HIS 33 1.628 6.422 10.328 1.00 0.00 C +ATOM 297 CG HIS 33 0.374 6.637 11.127 1.00 0.00 C +ATOM 298 CD2 HIS 33 -0.897 6.214 10.921 1.00 0.00 C +ATOM 299 ND1 HIS 33 0.352 7.343 12.312 1.00 0.00 N +ATOM 300 HD1 HIS 33 1.124 7.776 12.732 1.00 0.00 H +ATOM 301 CE1 HIS 33 -0.875 7.347 12.800 1.00 0.00 C +ATOM 302 NE2 HIS 33 -1.652 6.668 11.975 1.00 0.00 N +ATOM 303 HE2 HIS 33 -2.612 6.514 12.096 1.00 0.00 H +ATOM 304 C HIS 33 3.710 7.485 9.248 1.00 0.00 C +ATOM 305 O HIS 33 4.667 7.862 9.930 1.00 0.00 O +ATOM 306 N PRO 34 3.888 6.898 8.011 1.00 0.00 N +ATOM 307 CD PRO 34 3.009 6.000 7.233 1.00 0.00 C +ATOM 308 CA PRO 34 5.257 6.716 7.497 1.00 0.00 C +ATOM 309 CB PRO 34 5.046 5.884 6.235 1.00 0.00 C +ATOM 310 CG PRO 34 3.976 5.001 6.634 1.00 0.00 C +ATOM 311 C PRO 34 5.912 8.072 7.176 1.00 0.00 C +ATOM 312 O PRO 34 7.125 8.218 7.331 1.00 0.00 O +ATOM 313 N PHE 35 5.091 9.039 6.729 1.00 0.00 N +ATOM 314 H PHE 35 4.135 8.840 6.618 1.00 0.00 H +ATOM 315 CA PHE 35 5.518 10.414 6.381 1.00 0.00 C +ATOM 316 CB PHE 35 4.305 11.244 5.877 1.00 0.00 C +ATOM 317 CG PHE 35 4.319 11.576 4.386 1.00 0.00 C +ATOM 318 CD1 PHE 35 3.854 10.648 3.422 1.00 0.00 C +ATOM 319 CD2 PHE 35 4.725 12.857 3.942 1.00 0.00 C +ATOM 320 CE1 PHE 35 3.790 10.989 2.043 1.00 0.00 C +ATOM 321 CE2 PHE 35 4.665 13.213 2.566 1.00 0.00 C +ATOM 322 CZ PHE 35 4.196 12.276 1.614 1.00 0.00 C +ATOM 323 C PHE 35 6.161 11.133 7.584 1.00 0.00 C +ATOM 324 O PHE 35 7.254 11.685 7.442 1.00 0.00 O +ATOM 325 N ASN 36 5.516 11.068 8.762 1.00 0.00 N +ATOM 326 H ASN 36 4.660 10.591 8.833 1.00 0.00 H +ATOM 327 CA ASN 36 6.031 11.694 9.999 1.00 0.00 C +ATOM 328 CB ASN 36 4.935 11.882 11.081 1.00 0.00 C +ATOM 329 CG ASN 36 4.187 10.590 11.447 1.00 0.00 C +ATOM 330 OD1 ASN 36 2.966 10.523 11.316 1.00 0.00 O +ATOM 331 ND2 ASN 36 4.907 9.599 11.973 1.00 0.00 N +ATOM 332 HD21 ASN 36 4.438 8.770 12.207 1.00 0.00 H +ATOM 333 HD22 ASN 36 5.868 9.730 12.110 1.00 0.00 H +ATOM 334 C ASN 36 7.287 11.010 10.578 1.00 0.00 C +ATOM 335 O ASN 36 8.202 11.697 11.047 1.00 0.00 O +ATOM 336 N THR 37 7.331 9.671 10.488 1.00 0.00 N +ATOM 337 H THR 37 6.564 9.197 10.079 1.00 0.00 H +ATOM 338 CA THR 37 8.456 8.845 10.979 1.00 0.00 C +ATOM 339 CB THR 37 8.091 7.315 10.969 1.00 0.00 C +ATOM 340 OG1 THR 37 6.752 7.145 11.451 1.00 0.00 O +ATOM 341 HG1 THR 37 6.137 7.629 10.905 1.00 0.00 H +ATOM 342 CG2 THR 37 9.027 6.507 11.888 1.00 0.00 C +ATOM 343 C THR 37 9.719 9.130 10.127 1.00 0.00 C +ATOM 344 O THR 37 10.813 9.280 10.682 1.00 0.00 O +ATOM 345 N PHE 38 9.546 9.195 8.797 1.00 0.00 N +ATOM 346 H PHE 38 8.653 9.042 8.418 1.00 0.00 H +ATOM 347 CA PHE 38 10.621 9.490 7.829 1.00 0.00 C +ATOM 348 CB PHE 38 10.209 9.060 6.401 1.00 0.00 C +ATOM 349 CG PHE 38 10.523 7.605 6.065 1.00 0.00 C +ATOM 350 CD1 PHE 38 11.723 7.264 5.395 1.00 0.00 C +ATOM 351 CD2 PHE 38 9.621 6.566 6.401 1.00 0.00 C +ATOM 352 CE1 PHE 38 12.024 5.915 5.067 1.00 0.00 C +ATOM 353 CE2 PHE 38 9.909 5.213 6.080 1.00 0.00 C +ATOM 354 CZ PHE 38 11.115 4.887 5.411 1.00 0.00 C +ATOM 355 C PHE 38 11.129 10.945 7.839 1.00 0.00 C +ATOM 356 O PHE 38 12.332 11.177 7.675 1.00 0.00 O +ATOM 357 N ARG 39 10.208 11.902 8.035 1.00 0.00 N +ATOM 358 H ARG 39 9.264 11.648 8.150 1.00 0.00 H +ATOM 359 CA ARG 39 10.501 13.352 8.093 1.00 0.00 C +ATOM 360 CB ARG 39 9.214 14.180 8.008 1.00 0.00 C +ATOM 361 CG ARG 39 8.675 14.361 6.591 1.00 0.00 C +ATOM 362 CD ARG 39 7.389 15.186 6.561 1.00 0.00 C +ATOM 363 NE ARG 39 6.244 14.480 7.145 1.00 0.00 N +ATOM 364 HE ARG 39 6.398 13.582 7.505 1.00 0.00 H +ATOM 365 CZ ARG 39 5.004 14.964 7.229 1.00 0.00 C +ATOM 366 NH1 ARG 39 4.051 14.226 7.782 1.00 0.00 N +ATOM 367 HH11 ARG 39 4.265 13.314 8.132 1.00 0.00 H +ATOM 368 HH12 ARG 39 3.119 14.581 7.848 1.00 0.00 H +ATOM 369 NH2 ARG 39 4.704 16.174 6.768 1.00 0.00 N +ATOM 370 HH21 ARG 39 5.414 16.740 6.349 1.00 0.00 H +ATOM 371 HH22 ARG 39 3.768 16.519 6.840 1.00 0.00 H +ATOM 372 C ARG 39 11.312 13.776 9.330 1.00 0.00 C +ATOM 373 O ARG 39 12.161 14.670 9.236 1.00 0.00 O +ATOM 374 N LYS 40 11.039 13.127 10.471 1.00 0.00 N +ATOM 375 H LYS 40 10.330 12.438 10.480 1.00 0.00 H +ATOM 376 CA LYS 40 11.712 13.381 11.763 1.00 0.00 C +ATOM 377 CB LYS 40 11.021 12.614 12.898 1.00 0.00 C +ATOM 378 CG LYS 40 9.720 13.240 13.382 1.00 0.00 C +ATOM 379 CD LYS 40 9.095 12.421 14.506 1.00 0.00 C +ATOM 380 CE LYS 40 7.787 13.030 15.006 1.00 0.00 C +ATOM 381 NZ LYS 40 6.675 12.954 14.012 1.00 0.00 N +ATOM 382 HZ1 LYS 40 5.819 13.386 14.415 1.00 0.00 H +ATOM 383 HZ2 LYS 40 6.947 13.465 13.148 1.00 0.00 H +ATOM 384 HZ3 LYS 40 6.484 11.959 13.780 1.00 0.00 H +ATOM 385 C LYS 40 13.220 13.073 11.771 1.00 0.00 C +ATOM 386 O LYS 40 13.990 13.787 12.424 1.00 0.00 O +ATOM 387 N GLU 41 13.625 12.023 11.039 1.00 0.00 N +ATOM 388 H GLU 41 12.965 11.504 10.528 1.00 0.00 H +ATOM 389 CA GLU 41 15.031 11.572 10.933 1.00 0.00 C +ATOM 390 CB GLU 41 15.093 10.100 10.500 1.00 0.00 C +ATOM 391 CG GLU 41 14.685 9.114 11.590 1.00 0.00 C +ATOM 392 CD GLU 41 14.652 7.680 11.102 1.00 0.00 C +ATOM 393 OE1 GLU 41 13.573 7.231 10.663 1.00 0.00 O +ATOM 394 OE2 GLU 41 15.700 7.002 11.161 1.00 0.00 O +ATOM 395 C GLU 41 15.942 12.431 10.036 1.00 0.00 C +ATOM 396 O GLU 41 17.020 12.845 10.478 1.00 0.00 O +ATOM 397 N GLY 42 15.511 12.688 8.796 1.00 0.00 N +ATOM 398 H GLY 42 14.652 12.337 8.473 1.00 0.00 H +ATOM 399 CA GLY 42 16.294 13.499 7.871 1.00 0.00 C +ATOM 400 C GLY 42 16.366 12.979 6.446 1.00 0.00 C +ATOM 401 O GLY 42 17.422 13.083 5.810 1.00 0.00 O +ATOM 402 N PHE 43 15.251 12.425 5.954 1.00 0.00 N +ATOM 403 H PHE 43 14.455 12.375 6.525 1.00 0.00 H +ATOM 404 CA PHE 43 15.145 11.878 4.591 1.00 0.00 C +ATOM 405 CB PHE 43 14.906 10.341 4.622 1.00 0.00 C +ATOM 406 CG PHE 43 15.908 9.559 5.476 1.00 0.00 C +ATOM 407 CD1 PHE 43 15.565 9.145 6.784 1.00 0.00 C +ATOM 408 CD2 PHE 43 17.192 9.226 4.979 1.00 0.00 C +ATOM 409 CE1 PHE 43 16.484 8.414 7.587 1.00 0.00 C +ATOM 410 CE2 PHE 43 18.120 8.496 5.771 1.00 0.00 C +ATOM 411 CZ PHE 43 17.764 8.091 7.079 1.00 0.00 C +ATOM 412 C PHE 43 14.009 12.586 3.838 1.00 0.00 C +ATOM 413 O PHE 43 13.017 12.989 4.458 1.00 0.00 O +ATOM 414 N GLU 44 14.166 12.730 2.514 1.00 0.00 N +ATOM 415 H GLU 44 14.970 12.375 2.075 1.00 0.00 H +ATOM 416 CA GLU 44 13.190 13.399 1.625 1.00 0.00 C +ATOM 417 CB GLU 44 13.893 13.957 0.378 1.00 0.00 C +ATOM 418 CG GLU 44 14.833 15.130 0.641 1.00 0.00 C +ATOM 419 CD GLU 44 15.505 15.638 -0.621 1.00 0.00 C +ATOM 420 OE1 GLU 44 14.938 16.535 -1.280 1.00 0.00 O +ATOM 421 OE2 GLU 44 16.603 15.142 -0.952 1.00 0.00 O +ATOM 422 C GLU 44 12.006 12.505 1.206 1.00 0.00 C +ATOM 423 O GLU 44 12.208 11.350 0.811 1.00 0.00 O +ATOM 424 N VAL 45 10.783 13.040 1.340 1.00 0.00 N +ATOM 425 H VAL 45 10.675 13.953 1.687 1.00 0.00 H +ATOM 426 CA VAL 45 9.530 12.338 0.994 1.00 0.00 C +ATOM 427 CG1 VAL 45 8.214 13.229 3.065 1.00 0.00 C +ATOM 428 CG2 VAL 45 7.524 11.012 1.992 1.00 0.00 C +ATOM 429 C VAL 45 8.711 13.117 -0.068 1.00 0.00 C +ATOM 430 O VAL 45 8.494 14.328 0.074 1.00 0.00 O +ATOM 431 CB VAL 45 8.682 11.972 2.306 1.00 0.00 C +ATOM 432 N ASP 46 8.308 12.408 -1.132 1.00 0.00 N +ATOM 433 H ASP 46 8.543 11.458 -1.210 1.00 0.00 H +ATOM 434 CA ASP 46 7.508 12.954 -2.247 1.00 0.00 C +ATOM 435 CB ASP 46 8.365 13.127 -3.533 1.00 0.00 C +ATOM 436 CG ASP 46 9.214 11.895 -3.875 1.00 0.00 C +ATOM 437 OD1 ASP 46 8.733 11.033 -4.642 1.00 0.00 O +ATOM 438 OD2 ASP 46 10.362 11.802 -3.388 1.00 0.00 O +ATOM 439 C ASP 46 6.262 12.092 -2.530 1.00 0.00 C +ATOM 440 O ASP 46 6.331 10.862 -2.422 1.00 0.00 O +ATOM 441 N PHE 47 5.141 12.745 -2.873 1.00 0.00 N +ATOM 442 H PHE 47 5.132 13.726 -2.920 1.00 0.00 H +ATOM 443 CA PHE 47 3.868 12.067 -3.196 1.00 0.00 C +ATOM 444 CB PHE 47 2.685 12.625 -2.344 1.00 0.00 C +ATOM 445 CG PHE 47 2.607 14.158 -2.253 1.00 0.00 C +ATOM 446 CD1 PHE 47 1.836 14.900 -3.180 1.00 0.00 C +ATOM 447 CD2 PHE 47 3.274 14.857 -1.219 1.00 0.00 C +ATOM 448 CE1 PHE 47 1.728 16.314 -3.081 1.00 0.00 C +ATOM 449 CE2 PHE 47 3.176 16.272 -1.106 1.00 0.00 C +ATOM 450 CZ PHE 47 2.401 17.002 -2.041 1.00 0.00 C +ATOM 451 C PHE 47 3.565 12.181 -4.700 1.00 0.00 C +ATOM 452 O PHE 47 3.562 13.286 -5.252 1.00 0.00 O +ATOM 453 N VAL 48 3.332 11.030 -5.346 1.00 0.00 N +ATOM 454 H VAL 48 3.339 10.183 -4.856 1.00 0.00 H +ATOM 455 CA VAL 48 3.048 10.939 -6.793 1.00 0.00 C +ATOM 456 CB VAL 48 4.247 10.277 -7.601 1.00 0.00 C +ATOM 457 CG1 VAL 48 4.044 10.415 -9.106 1.00 0.00 C +ATOM 458 CG2 VAL 48 5.580 10.929 -7.233 1.00 0.00 C +ATOM 459 C VAL 48 1.754 10.141 -7.043 1.00 0.00 C +ATOM 460 O VAL 48 1.456 9.182 -6.320 1.00 0.00 O +ATOM 461 N SER 49 0.997 10.581 -8.058 1.00 0.00 N +ATOM 462 H SER 49 1.266 11.375 -8.571 1.00 0.00 H +ATOM 463 CA SER 49 -0.260 9.958 -8.500 1.00 0.00 C +ATOM 464 CB SER 49 -1.373 11.012 -8.590 1.00 0.00 C +ATOM 465 OG SER 49 -0.976 12.127 -9.369 1.00 0.00 O +ATOM 466 HG SER 49 -0.234 12.579 -8.958 1.00 0.00 H +ATOM 467 C SER 49 -0.004 9.307 -9.872 1.00 0.00 C +ATOM 468 O SER 49 0.654 9.917 -10.725 1.00 0.00 O +ATOM 469 N GLU 50 -0.526 8.087 -10.066 1.00 0.00 N +ATOM 470 H GLU 50 -1.057 7.680 -9.346 1.00 0.00 H +ATOM 471 CA GLU 50 -0.374 7.265 -11.296 1.00 0.00 C +ATOM 472 CB GLU 50 -1.276 6.016 -11.233 1.00 0.00 C +ATOM 473 CG GLU 50 -2.732 6.251 -10.786 1.00 0.00 C +ATOM 474 CD GLU 50 -3.615 5.044 -11.005 1.00 0.00 C +ATOM 475 OE1 GLU 50 -3.669 4.169 -10.115 1.00 0.00 O +ATOM 476 OE2 GLU 50 -4.265 4.973 -12.069 1.00 0.00 O +ATOM 477 C GLU 50 -0.485 7.931 -12.689 1.00 0.00 C +ATOM 478 O GLU 50 0.382 7.713 -13.545 1.00 0.00 O +ATOM 479 N THR 51 -1.552 8.714 -12.900 1.00 0.00 N +ATOM 480 H THR 51 -2.219 8.843 -12.190 1.00 0.00 H +ATOM 481 CA THR 51 -1.813 9.427 -14.165 1.00 0.00 C +ATOM 482 CB THR 51 -3.272 9.188 -14.676 1.00 0.00 C +ATOM 483 OG1 THR 51 -4.209 9.484 -13.633 1.00 0.00 O +ATOM 484 HG1 THR 51 -4.072 8.882 -12.899 1.00 0.00 H +ATOM 485 CG2 THR 51 -3.457 7.745 -15.135 1.00 0.00 C +ATOM 486 C THR 51 -1.562 10.935 -13.999 1.00 0.00 C +ATOM 487 O THR 51 -1.137 11.610 -14.946 1.00 0.00 O +ATOM 488 N GLY 52 -1.796 11.430 -12.779 1.00 0.00 N +ATOM 489 H GLY 52 -2.103 10.853 -12.045 1.00 0.00 H +ATOM 490 CA GLY 52 -1.613 12.839 -12.457 1.00 0.00 C +ATOM 491 C GLY 52 -2.945 13.535 -12.204 1.00 0.00 C +ATOM 492 O GLY 52 -3.074 14.738 -12.447 1.00 0.00 O +ATOM 493 N LYS 53 -3.949 12.749 -11.791 1.00 0.00 N +ATOM 494 H LYS 53 -3.779 11.789 -11.684 1.00 0.00 H +ATOM 495 CA LYS 53 -5.314 13.221 -11.480 1.00 0.00 C +ATOM 496 CB LYS 53 -6.291 12.910 -12.634 1.00 0.00 C +ATOM 497 CG LYS 53 -6.123 13.778 -13.876 1.00 0.00 C +ATOM 498 CD LYS 53 -7.127 13.400 -14.954 1.00 0.00 C +ATOM 499 CE LYS 53 -6.960 14.265 -16.192 1.00 0.00 C +ATOM 500 NZ LYS 53 -7.937 13.905 -17.257 1.00 0.00 N +ATOM 501 HZ1 LYS 53 -7.789 14.517 -18.084 1.00 0.00 H +ATOM 502 HZ2 LYS 53 -7.798 12.911 -17.532 1.00 0.00 H +ATOM 503 HZ3 LYS 53 -8.904 14.033 -16.898 1.00 0.00 H +ATOM 504 C LYS 53 -5.812 12.538 -10.195 1.00 0.00 C +ATOM 505 O LYS 53 -6.812 12.966 -9.601 1.00 0.00 O +ATOM 506 N PHE 54 -5.074 11.507 -9.760 1.00 0.00 N +ATOM 507 H PHE 54 -4.262 11.253 -10.255 1.00 0.00 H +ATOM 508 CA PHE 54 -5.370 10.695 -8.564 1.00 0.00 C +ATOM 509 CB PHE 54 -4.734 9.297 -8.723 1.00 0.00 C +ATOM 510 CG PHE 54 -5.488 8.354 -9.663 1.00 0.00 C +ATOM 511 CD1 PHE 54 -6.068 7.169 -9.162 1.00 0.00 C +ATOM 512 CD2 PHE 54 -5.604 8.625 -11.048 1.00 0.00 C +ATOM 513 CE1 PHE 54 -6.758 6.265 -10.018 1.00 0.00 C +ATOM 514 CE2 PHE 54 -6.290 7.733 -11.918 1.00 0.00 C +ATOM 515 CZ PHE 54 -6.868 6.549 -11.400 1.00 0.00 C +ATOM 516 C PHE 54 -4.930 11.302 -7.227 1.00 0.00 C +ATOM 517 O PHE 54 -4.030 12.148 -7.192 1.00 0.00 O +ATOM 518 N GLY 55 -5.593 10.878 -6.146 1.00 0.00 N +ATOM 519 H GLY 55 -6.326 10.227 -6.215 1.00 0.00 H +ATOM 520 CA GLY 55 -5.266 11.357 -4.813 1.00 0.00 C +ATOM 521 C GLY 55 -6.443 11.757 -3.938 1.00 0.00 C +ATOM 522 O GLY 55 -6.532 11.297 -2.794 1.00 0.00 O +ATOM 523 N TRP 56 -7.338 12.601 -4.467 1.00 0.00 N +ATOM 524 H TRP 56 -7.213 12.905 -5.391 1.00 0.00 H +ATOM 525 CA TRP 56 -8.512 13.101 -3.728 1.00 0.00 C +ATOM 526 CB TRP 56 -8.968 14.475 -4.266 1.00 0.00 C +ATOM 527 CG TRP 56 -9.276 14.587 -5.792 1.00 0.00 C +ATOM 528 CD2 TRP 56 -8.422 15.130 -6.823 1.00 0.00 C +ATOM 529 CE2 TRP 56 -9.149 15.063 -8.046 1.00 0.00 C +ATOM 530 CE3 TRP 56 -7.114 15.668 -6.836 1.00 0.00 C +ATOM 531 CD1 TRP 56 -10.446 14.227 -6.426 1.00 0.00 C +ATOM 532 NE1 TRP 56 -10.371 14.511 -7.767 1.00 0.00 N +ATOM 533 HE1 TRP 56 -11.084 14.342 -8.417 1.00 0.00 H +ATOM 534 CZ2 TRP 56 -8.614 15.515 -9.277 1.00 0.00 C +ATOM 535 CZ3 TRP 56 -6.576 16.121 -8.067 1.00 0.00 C +ATOM 536 CH2 TRP 56 -7.333 16.038 -9.269 1.00 0.00 C +ATOM 537 C TRP 56 -9.728 12.172 -3.581 1.00 0.00 C +ATOM 538 O TRP 56 -9.998 11.341 -4.457 1.00 0.00 O +ATOM 539 N ASP 57 -10.439 12.344 -2.458 1.00 0.00 N +ATOM 540 H ASP 57 -10.169 13.019 -1.797 1.00 0.00 H +ATOM 541 CA ASP 57 -11.645 11.583 -2.094 1.00 0.00 C +ATOM 542 CB ASP 57 -11.350 10.557 -0.970 1.00 0.00 C +ATOM 543 CG ASP 57 -9.927 10.646 -0.437 1.00 0.00 C +ATOM 544 OD1 ASP 57 -9.047 9.929 -0.963 1.00 0.00 O +ATOM 545 OD2 ASP 57 -9.686 11.422 0.514 1.00 0.00 O +ATOM 546 C ASP 57 -12.751 12.565 -1.665 1.00 0.00 C +ATOM 547 O ASP 57 -13.638 12.874 -2.470 1.00 0.00 O +ATOM 548 N GLU 58 -12.690 13.047 -0.410 1.00 0.00 N +ATOM 549 H GLU 58 -11.959 12.768 0.184 1.00 0.00 H +ATOM 550 CA GLU 58 -13.654 14.001 0.189 1.00 0.00 C +ATOM 551 CB GLU 58 -15.047 13.346 0.412 1.00 0.00 C +ATOM 552 CG GLU 58 -15.083 11.964 1.098 1.00 0.00 C +ATOM 553 CD GLU 58 -16.490 11.409 1.209 1.00 0.00 C +ATOM 554 OE1 GLU 58 -17.171 11.702 2.213 1.00 0.00 O +ATOM 555 OE2 GLU 58 -16.917 10.680 0.289 1.00 0.00 O +ATOM 556 C GLU 58 -13.098 14.637 1.490 1.00 0.00 C +ATOM 557 O GLU 58 -11.880 14.822 1.603 1.00 0.00 O +ATOM 558 N HIS 59 -13.984 14.963 2.448 1.00 0.00 N +ATOM 559 H HIS 59 -14.946 14.826 2.325 1.00 0.00 H +ATOM 560 CA HIS 59 -13.626 15.565 3.747 1.00 0.00 C +ATOM 561 CB HIS 59 -14.732 16.541 4.203 1.00 0.00 C +ATOM 562 CG HIS 59 -14.256 17.641 5.112 1.00 0.00 C +ATOM 563 CD2 HIS 59 -14.519 17.898 6.417 1.00 0.00 C +ATOM 564 ND1 HIS 59 -13.417 18.651 4.688 1.00 0.00 N +ATOM 565 HD1 HIS 59 -13.047 18.745 3.785 1.00 0.00 H +ATOM 566 CE1 HIS 59 -13.183 19.480 5.690 1.00 0.00 C +ATOM 567 NE2 HIS 59 -13.840 19.045 6.750 1.00 0.00 N +ATOM 568 HE2 HIS 59 -13.843 19.472 7.632 1.00 0.00 H +ATOM 569 C HIS 59 -13.401 14.456 4.800 1.00 0.00 C +ATOM 570 O HIS 59 -12.477 14.558 5.615 1.00 0.00 O +ATOM 571 N SER 60 -14.268 13.429 4.786 1.00 0.00 N +ATOM 572 H SER 60 -15.009 13.425 4.141 1.00 0.00 H +ATOM 573 CA SER 60 -14.211 12.254 5.687 1.00 0.00 C +ATOM 574 CB SER 60 -14.657 12.591 7.118 1.00 0.00 C +ATOM 575 OG SER 60 -13.785 13.526 7.730 1.00 0.00 O +ATOM 576 HG SER 60 -13.801 14.362 7.257 1.00 0.00 H +ATOM 577 C SER 60 -15.064 11.100 5.143 1.00 0.00 C +ATOM 578 O SER 60 -16.190 11.322 4.679 1.00 0.00 O +ATOM 579 N LEU 61 -14.505 9.878 5.212 1.00 0.00 N +ATOM 580 H LEU 61 -13.613 9.780 5.610 1.00 0.00 H +ATOM 581 CA LEU 61 -15.097 8.589 4.761 1.00 0.00 C +ATOM 582 CB LEU 61 -15.587 7.740 5.974 1.00 0.00 C +ATOM 583 CG LEU 61 -16.494 8.228 7.129 1.00 0.00 C +ATOM 584 CD1 LEU 61 -17.348 7.069 7.611 1.00 0.00 C +ATOM 585 CD2 LEU 61 -15.692 8.829 8.294 1.00 0.00 C +ATOM 586 C LEU 61 -16.112 8.562 3.583 1.00 0.00 C +ATOM 587 O LEU 61 -15.698 8.422 2.426 1.00 0.00 O +ATOM 588 N ALA 62 -17.412 8.696 3.891 1.00 0.00 N +ATOM 589 H ALA 62 -17.688 8.813 4.824 1.00 0.00 H +ATOM 590 CA ALA 62 -18.505 8.689 2.900 1.00 0.00 C +ATOM 591 CB ALA 62 -19.169 7.303 2.838 1.00 0.00 C +ATOM 592 C ALA 62 -19.557 9.754 3.229 1.00 0.00 C +ATOM 593 O ALA 62 -20.214 10.272 2.318 1.00 0.00 O +ATOM 594 N LYS 63 -19.680 10.086 4.528 1.00 0.00 N +ATOM 595 H LYS 63 -19.100 9.651 5.190 1.00 0.00 H +ATOM 596 CA LYS 63 -20.629 11.075 5.120 1.00 0.00 C +ATOM 597 CB LYS 63 -19.974 12.473 5.326 1.00 0.00 C +ATOM 598 CG LYS 63 -19.381 13.176 4.087 1.00 0.00 C +ATOM 599 CD LYS 63 -18.880 14.569 4.429 1.00 0.00 C +ATOM 600 CE LYS 63 -18.347 15.281 3.197 1.00 0.00 C +ATOM 601 NZ LYS 63 -17.900 16.667 3.508 1.00 0.00 N +ATOM 602 HZ1 LYS 63 -17.543 17.118 2.641 1.00 0.00 H +ATOM 603 HZ2 LYS 63 -18.702 17.215 3.879 1.00 0.00 H +ATOM 604 HZ3 LYS 63 -17.143 16.636 4.220 1.00 0.00 H +ATOM 605 C LYS 63 -22.062 11.193 4.535 1.00 0.00 C +ATOM 606 O LYS 63 -22.237 11.621 3.385 1.00 0.00 O +ATOM 607 N ASP 64 -23.058 10.790 5.337 1.00 0.00 N +ATOM 608 H ASP 64 -22.863 10.446 6.236 1.00 0.00 H +ATOM 609 CA ASP 64 -24.484 10.823 4.962 1.00 0.00 C +ATOM 610 CB ASP 64 -25.137 9.426 5.122 1.00 0.00 C +ATOM 611 CG ASP 64 -24.818 8.753 6.465 1.00 0.00 C +ATOM 612 OD1 ASP 64 -23.808 8.019 6.543 1.00 0.00 O +ATOM 613 OD2 ASP 64 -25.586 8.950 7.432 1.00 0.00 O +ATOM 614 C ASP 64 -25.295 11.895 5.715 1.00 0.00 C +ATOM 615 O ASP 64 -25.019 12.169 6.890 1.00 0.00 O +ATOM 616 N PHE 65 -26.282 12.483 5.024 1.00 0.00 N +ATOM 617 H PHE 65 -26.453 12.229 4.091 1.00 0.00 H +ATOM 618 CA PHE 65 -27.171 13.525 5.571 1.00 0.00 C +ATOM 619 CB PHE 65 -27.218 14.770 4.629 1.00 0.00 C +ATOM 620 CG PHE 65 -27.423 14.458 3.139 1.00 0.00 C +ATOM 621 CD1 PHE 65 -26.317 14.206 2.291 1.00 0.00 C +ATOM 622 CD2 PHE 65 -28.720 14.458 2.573 1.00 0.00 C +ATOM 623 CE1 PHE 65 -26.498 13.958 0.902 1.00 0.00 C +ATOM 624 CE2 PHE 65 -28.916 14.211 1.186 1.00 0.00 C +ATOM 625 CZ PHE 65 -27.802 13.961 0.348 1.00 0.00 C +ATOM 626 C PHE 65 -28.587 12.989 5.872 1.00 0.00 C +ATOM 627 O PHE 65 -29.342 13.607 6.636 1.00 0.00 O +ATOM 628 N LEU 66 -28.910 11.826 5.286 1.00 0.00 N +ATOM 629 H LEU 66 -28.266 11.369 4.702 1.00 0.00 H +ATOM 630 CA LEU 66 -30.209 11.142 5.448 1.00 0.00 C +ATOM 631 CB LEU 66 -30.743 10.657 4.083 1.00 0.00 C +ATOM 632 CG LEU 66 -31.208 11.637 2.989 1.00 0.00 C +ATOM 633 CD1 LEU 66 -30.744 11.121 1.636 1.00 0.00 C +ATOM 634 CD2 LEU 66 -32.733 11.837 2.992 1.00 0.00 C +ATOM 635 C LEU 66 -30.090 9.949 6.413 1.00 0.00 C +ATOM 636 O LEU 66 -28.990 9.416 6.600 1.00 0.00 O +ATOM 637 N ASN 67 -31.222 9.547 7.011 1.00 0.00 N +ATOM 638 H ASN 67 -32.070 10.007 6.824 1.00 0.00 H +ATOM 639 CA ASN 67 -31.301 8.425 7.965 1.00 0.00 C +ATOM 640 CB ASN 67 -32.209 8.808 9.151 1.00 0.00 C +ATOM 641 CG ASN 67 -31.840 8.083 10.448 1.00 0.00 C +ATOM 642 OD1 ASN 67 -31.035 8.575 11.241 1.00 0.00 O +ATOM 643 ND2 ASN 67 -32.443 6.918 10.670 1.00 0.00 N +ATOM 644 HD21 ASN 67 -32.218 6.441 11.496 1.00 0.00 H +ATOM 645 HD22 ASN 67 -33.084 6.578 10.011 1.00 0.00 H +ATOM 646 C ASN 67 -31.833 7.158 7.269 1.00 0.00 C +ATOM 647 O ASN 67 -32.632 7.253 6.330 1.00 0.00 O +ATOM 648 N GLY 68 -31.376 5.995 7.740 1.00 0.00 N +ATOM 649 H GLY 68 -30.739 5.962 8.488 1.00 0.00 H +ATOM 650 CA GLY 68 -31.788 4.714 7.180 1.00 0.00 C +ATOM 651 C GLY 68 -31.291 3.536 8.000 1.00 0.00 C +ATOM 652 O GLY 68 -30.426 3.709 8.868 1.00 0.00 O +ATOM 653 N GLN 69 -31.840 2.349 7.716 1.00 0.00 N +ATOM 654 H GLN 69 -32.517 2.298 7.009 1.00 0.00 H +ATOM 655 CA GLN 69 -31.492 1.093 8.403 1.00 0.00 C +ATOM 656 CB GLN 69 -32.759 0.396 8.963 1.00 0.00 C +ATOM 657 CG GLN 69 -33.971 0.267 8.014 1.00 0.00 C +ATOM 658 CD GLN 69 -35.152 -0.426 8.666 1.00 0.00 C +ATOM 659 OE1 GLN 69 -35.270 -1.650 8.621 1.00 0.00 O +ATOM 660 NE2 GLN 69 -36.036 0.357 9.277 1.00 0.00 N +ATOM 661 HE21 GLN 69 -35.896 1.327 9.284 1.00 0.00 H +ATOM 662 HE22 GLN 69 -36.805 -0.077 9.702 1.00 0.00 H +ATOM 663 C GLN 69 -30.653 0.120 7.545 1.00 0.00 C +ATOM 664 O GLN 69 -29.916 -0.711 8.092 1.00 0.00 O +ATOM 665 N ASP 70 -30.763 0.254 6.216 1.00 0.00 N +ATOM 666 H ASP 70 -31.345 0.947 5.834 1.00 0.00 H +ATOM 667 CA ASP 70 -30.048 -0.589 5.237 1.00 0.00 C +ATOM 668 CB ASP 70 -30.985 -0.979 4.080 1.00 0.00 C +ATOM 669 CG ASP 70 -32.136 -1.878 4.523 1.00 0.00 C +ATOM 670 OD1 ASP 70 -33.207 -1.344 4.888 1.00 0.00 O +ATOM 671 OD2 ASP 70 -31.977 -3.118 4.489 1.00 0.00 O +ATOM 672 C ASP 70 -28.777 0.066 4.672 1.00 0.00 C +ATOM 673 O ASP 70 -27.790 -0.631 4.405 1.00 0.00 O +ATOM 674 N GLU 71 -28.805 1.399 4.523 1.00 0.00 N +ATOM 675 H GLU 71 -29.612 1.897 4.781 1.00 0.00 H +ATOM 676 CA GLU 71 -27.687 2.210 3.989 1.00 0.00 C +ATOM 677 CB GLU 71 -28.169 3.623 3.586 1.00 0.00 C +ATOM 678 CG GLU 71 -29.024 4.396 4.615 1.00 0.00 C +ATOM 679 CD GLU 71 -29.442 5.765 4.116 1.00 0.00 C +ATOM 680 OE1 GLU 71 -30.518 5.869 3.490 1.00 0.00 O +ATOM 681 OE2 GLU 71 -28.695 6.739 4.351 1.00 0.00 O +ATOM 682 C GLU 71 -26.421 2.287 4.871 1.00 0.00 C +ATOM 683 O GLU 71 -25.301 2.264 4.346 1.00 0.00 O +ATOM 684 N THR 72 -26.619 2.342 6.197 1.00 0.00 N +ATOM 685 H THR 72 -27.545 2.325 6.532 1.00 0.00 H +ATOM 686 CA THR 72 -25.534 2.420 7.200 1.00 0.00 C +ATOM 687 CB THR 72 -26.086 2.736 8.623 1.00 0.00 C +ATOM 688 OG1 THR 72 -27.162 1.841 8.936 1.00 0.00 O +ATOM 689 HG1 THR 72 -27.897 1.972 8.332 1.00 0.00 H +ATOM 690 CG2 THR 72 -26.580 4.176 8.705 1.00 0.00 C +ATOM 691 C THR 72 -24.677 1.136 7.243 1.00 0.00 C +ATOM 692 O THR 72 -23.449 1.213 7.391 1.00 0.00 O +ATOM 693 N ASP 73 -25.337 -0.023 7.092 1.00 0.00 N +ATOM 694 H ASP 73 -26.314 -0.009 6.979 1.00 0.00 H +ATOM 695 CA ASP 73 -24.701 -1.358 7.077 1.00 0.00 C +ATOM 696 CG ASP 73 -26.458 -2.455 8.573 1.00 0.00 C +ATOM 697 OD1 ASP 73 -27.498 -1.775 8.709 1.00 0.00 O +ATOM 698 OD2 ASP 73 -25.975 -3.142 9.501 1.00 0.00 O +ATOM 699 C ASP 73 -23.855 -1.591 5.809 1.00 0.00 C +ATOM 700 O ASP 73 -22.742 -2.123 5.896 1.00 0.00 O +ATOM 701 CB ASP 73 -25.760 -2.466 7.216 1.00 0.00 C +ATOM 702 N PHE 74 -24.402 -1.186 4.651 1.00 0.00 N +ATOM 703 H PHE 74 -25.294 -0.773 4.656 1.00 0.00 H +ATOM 704 CA PHE 74 -23.757 -1.308 3.326 1.00 0.00 C +ATOM 705 CB PHE 74 -24.793 -1.090 2.190 1.00 0.00 C +ATOM 706 CG PHE 74 -25.887 -2.241 2.054 1.00 0.00 C +ATOM 707 CD1 PHE 74 -27.280 -2.234 1.799 1.00 0.00 C +ATOM 708 CD2 PHE 74 -26.049 -3.329 1.165 1.00 0.00 C +ATOM 709 CE1 PHE 74 -26.560 -3.299 1.107 1.00 0.00 C +ATOM 710 CE2 PHE 74 -27.310 -2.644 1.483 1.00 0.00 C +ATOM 711 CZ PHE 74 -26.109 -2.385 1.921 1.00 0.00 C +ATOM 712 C PHE 74 -22.538 -0.395 3.100 1.00 0.00 C +ATOM 713 O PHE 74 -21.562 -0.818 2.468 1.00 0.00 O +ATOM 714 N LYS 75 -22.607 0.842 3.615 1.00 0.00 N +ATOM 715 H LYS 75 -23.418 1.121 4.102 1.00 0.00 H +ATOM 716 CA LYS 75 -21.534 1.856 3.496 1.00 0.00 C +ATOM 717 CB LYS 75 -22.052 3.247 3.888 1.00 0.00 C +ATOM 718 CG LYS 75 -22.970 3.894 2.859 1.00 0.00 C +ATOM 719 CD LYS 75 -23.435 5.267 3.317 1.00 0.00 C +ATOM 720 CE LYS 75 -24.350 5.911 2.288 1.00 0.00 C +ATOM 721 NZ LYS 75 -24.812 7.258 2.722 1.00 0.00 N +ATOM 722 HZ1 LYS 75 -25.335 7.173 3.616 1.00 0.00 H +ATOM 723 HZ2 LYS 75 -23.989 7.878 2.861 1.00 0.00 H +ATOM 724 HZ3 LYS 75 -25.433 7.664 1.994 1.00 0.00 H +ATOM 725 C LYS 75 -20.246 1.536 4.279 1.00 0.00 C +ATOM 726 O LYS 75 -19.146 1.661 3.730 1.00 0.00 O +ATOM 727 N ASN 76 -20.401 1.109 5.547 1.00 0.00 N +ATOM 728 H ASN 76 -21.308 1.023 5.915 1.00 0.00 H +ATOM 729 CA ASN 76 -19.318 0.735 6.503 1.00 0.00 C +ATOM 730 CB ASN 76 -18.678 -0.624 6.118 1.00 0.00 C +ATOM 731 CG ASN 76 -18.313 -1.480 7.332 1.00 0.00 C +ATOM 732 OD1 ASN 76 -17.199 -1.397 7.853 1.00 0.00 O +ATOM 733 ND2 ASN 76 -19.250 -2.315 7.774 1.00 0.00 N +ATOM 734 HD21 ASN 76 -19.032 -2.870 8.551 1.00 0.00 H +ATOM 735 HD22 ASN 76 -20.116 -2.349 7.315 1.00 0.00 H +ATOM 736 C ASN 76 -18.221 1.804 6.748 1.00 0.00 C +ATOM 737 O ASN 76 -17.951 2.635 5.873 1.00 0.00 O +ATOM 738 N LYS 77 -17.609 1.761 7.941 1.00 0.00 N +ATOM 739 H LYS 77 -17.862 1.083 8.605 1.00 0.00 H +ATOM 740 CA LYS 77 -16.539 2.692 8.352 1.00 0.00 C +ATOM 741 CB LYS 77 -16.809 3.250 9.762 1.00 0.00 C +ATOM 742 CG LYS 77 -18.020 4.172 9.865 1.00 0.00 C +ATOM 743 CD LYS 77 -18.213 4.675 11.292 1.00 0.00 C +ATOM 744 CE LYS 77 -19.420 5.601 11.419 1.00 0.00 C +ATOM 745 NZ LYS 77 -19.242 6.914 10.728 1.00 0.00 N +ATOM 746 HZ1 LYS 77 -18.424 7.411 11.135 1.00 0.00 H +ATOM 747 HZ2 LYS 77 -20.098 7.491 10.855 1.00 0.00 H +ATOM 748 HZ3 LYS 77 -19.080 6.752 9.714 1.00 0.00 H +ATOM 749 C LYS 77 -15.149 2.027 8.294 1.00 0.00 C +ATOM 750 O LYS 77 -14.898 1.034 8.992 1.00 0.00 O +ATOM 751 N ASP 78 -14.282 2.555 7.417 1.00 0.00 N +ATOM 752 H ASP 78 -14.545 3.320 6.858 1.00 0.00 H +ATOM 753 CA ASP 78 -12.905 2.063 7.211 1.00 0.00 C +ATOM 754 CB ASP 78 -12.753 1.362 5.833 1.00 0.00 C +ATOM 755 CG ASP 78 -13.360 2.162 4.671 1.00 0.00 C +ATOM 756 OD1 ASP 78 -14.556 1.961 4.365 1.00 0.00 O +ATOM 757 OD2 ASP 78 -12.634 2.977 4.061 1.00 0.00 O +ATOM 758 C ASP 78 -11.843 3.165 7.382 1.00 0.00 C +ATOM 759 O ASP 78 -10.787 2.918 7.977 1.00 0.00 O +ATOM 760 N SER 79 -12.141 4.363 6.858 1.00 0.00 N +ATOM 761 H SER 79 -12.999 4.504 6.400 1.00 0.00 H +ATOM 762 CA SER 79 -11.253 5.538 6.915 1.00 0.00 C +ATOM 763 CB SER 79 -11.177 6.210 5.535 1.00 0.00 C +ATOM 764 OG SER 79 -12.468 6.513 5.033 1.00 0.00 O +ATOM 765 HG SER 79 -12.387 6.932 4.173 1.00 0.00 H +ATOM 766 C SER 79 -11.682 6.561 7.982 1.00 0.00 C +ATOM 767 O SER 79 -12.861 6.608 8.354 1.00 0.00 O +ATOM 768 N ASP 80 -10.718 7.363 8.458 1.00 0.00 N +ATOM 769 H ASP 80 -9.799 7.282 8.122 1.00 0.00 H +ATOM 770 CA ASP 80 -10.931 8.403 9.484 1.00 0.00 C +ATOM 771 CB ASP 80 -9.804 8.366 10.549 1.00 0.00 C +ATOM 772 CG ASP 80 -8.410 8.150 9.952 1.00 0.00 C +ATOM 773 OD1 ASP 80 -7.743 9.149 9.611 1.00 0.00 O +ATOM 774 OD2 ASP 80 -7.983 6.981 9.839 1.00 0.00 O +ATOM 775 C ASP 80 -11.136 9.826 8.911 1.00 0.00 C +ATOM 776 O ASP 80 -12.277 10.302 8.857 1.00 0.00 O +ATOM 777 N PHE 81 -10.043 10.482 8.494 1.00 0.00 N +ATOM 778 H PHE 81 -9.160 10.062 8.561 1.00 0.00 H +ATOM 779 CA PHE 81 -10.068 11.838 7.912 1.00 0.00 C +ATOM 780 CB PHE 81 -9.275 12.868 8.785 1.00 0.00 C +ATOM 781 CG PHE 81 -7.981 12.340 9.416 1.00 0.00 C +ATOM 782 CD1 PHE 81 -7.953 11.968 10.781 1.00 0.00 C +ATOM 783 CD2 PHE 81 -6.780 12.259 8.670 1.00 0.00 C +ATOM 784 CE1 PHE 81 -6.750 11.522 11.397 1.00 0.00 C +ATOM 785 CE2 PHE 81 -5.570 11.816 9.272 1.00 0.00 C +ATOM 786 CZ PHE 81 -5.556 11.447 10.639 1.00 0.00 C +ATOM 787 C PHE 81 -9.573 11.853 6.455 1.00 0.00 C +ATOM 788 O PHE 81 -8.455 11.400 6.172 1.00 0.00 O +ATOM 789 N ASN 82 -10.425 12.351 5.546 1.00 0.00 N +ATOM 790 H ASN 82 -11.310 12.678 5.818 1.00 0.00 H +ATOM 791 CA ASN 82 -10.121 12.449 4.106 1.00 0.00 C +ATOM 792 CB ASN 82 -11.307 11.966 3.249 1.00 0.00 C +ATOM 793 CG ASN 82 -11.633 10.486 3.452 1.00 0.00 C +ATOM 794 OD1 ASN 82 -11.950 10.043 4.560 1.00 0.00 O +ATOM 795 ND2 ASN 82 -11.575 9.719 2.369 1.00 0.00 N +ATOM 796 HD21 ASN 82 -11.783 8.768 2.474 1.00 0.00 H +ATOM 797 HD22 ASN 82 -11.326 10.123 1.515 1.00 0.00 H +ATOM 798 C ASN 82 -9.719 13.873 3.702 1.00 0.00 C +ATOM 799 O ASN 82 -10.405 14.844 4.044 1.00 0.00 O +ATOM 800 N LYS 83 -8.570 13.980 3.027 1.00 0.00 N +ATOM 801 H LYS 83 -8.035 13.183 2.816 1.00 0.00 H +ATOM 802 CA LYS 83 -8.011 15.254 2.549 1.00 0.00 C +ATOM 803 CB LYS 83 -6.701 15.578 3.284 1.00 0.00 C +ATOM 804 CG LYS 83 -6.865 15.937 4.758 1.00 0.00 C +ATOM 805 CD LYS 83 -5.524 16.238 5.405 1.00 0.00 C +ATOM 806 CE LYS 83 -5.687 16.595 6.874 1.00 0.00 C +ATOM 807 NZ LYS 83 -4.380 16.892 7.522 1.00 0.00 N +ATOM 808 HZ1 LYS 83 -3.929 17.696 7.040 1.00 0.00 H +ATOM 809 HZ2 LYS 83 -4.535 17.131 8.522 1.00 0.00 H +ATOM 810 HZ3 LYS 83 -3.763 16.058 7.456 1.00 0.00 H +ATOM 811 C LYS 83 -7.752 15.143 1.044 1.00 0.00 C +ATOM 812 O LYS 83 -7.523 14.035 0.542 1.00 0.00 O +ATOM 813 N THR 84 -7.790 16.282 0.338 1.00 0.00 N +ATOM 814 H THR 84 -7.972 17.134 0.794 1.00 0.00 H +ATOM 815 CA THR 84 -7.562 16.344 -1.120 1.00 0.00 C +ATOM 816 CB THR 84 -8.320 17.564 -1.795 1.00 0.00 C +ATOM 817 OG1 THR 84 -7.982 17.648 -3.187 1.00 0.00 O +ATOM 818 HG1 THR 84 -8.268 16.856 -3.647 1.00 0.00 H +ATOM 819 CG2 THR 84 -8.008 18.906 -1.098 1.00 0.00 C +ATOM 820 C THR 84 -6.062 16.275 -1.503 1.00 0.00 C +ATOM 821 O THR 84 -5.288 17.205 -1.224 1.00 0.00 O +ATOM 822 N LEU 85 -5.675 15.130 -2.080 1.00 0.00 N +ATOM 823 H LEU 85 -6.321 14.407 -2.236 1.00 0.00 H +ATOM 824 CA LEU 85 -4.301 14.842 -2.526 1.00 0.00 C +ATOM 825 CB LEU 85 -3.876 13.424 -2.078 1.00 0.00 C +ATOM 826 CG LEU 85 -3.772 13.059 -0.586 1.00 0.00 C +ATOM 827 CD1 LEU 85 -4.932 12.148 -0.170 1.00 0.00 C +ATOM 828 CD2 LEU 85 -2.442 12.365 -0.318 1.00 0.00 C +ATOM 829 C LEU 85 -4.243 14.970 -4.057 1.00 0.00 C +ATOM 830 O LEU 85 -5.155 14.501 -4.749 1.00 0.00 O +ATOM 831 N ALA 86 -3.212 15.658 -4.564 1.00 0.00 N +ATOM 832 H ALA 86 -2.529 16.043 -3.973 1.00 0.00 H +ATOM 833 CA ALA 86 -3.022 15.885 -6.007 1.00 0.00 C +ATOM 834 CB ALA 86 -3.308 17.350 -6.352 1.00 0.00 C +ATOM 835 C ALA 86 -1.628 15.477 -6.506 1.00 0.00 C +ATOM 836 O ALA 86 -0.879 14.810 -5.781 1.00 0.00 O +ATOM 837 N LYS 87 -1.300 15.890 -7.739 1.00 0.00 N +ATOM 838 H LYS 87 -1.931 16.431 -8.264 1.00 0.00 H +ATOM 839 CA LYS 87 -0.024 15.594 -8.410 1.00 0.00 C +ATOM 840 CB LYS 87 -0.271 15.222 -9.890 1.00 0.00 C +ATOM 841 CG LYS 87 -0.946 16.307 -10.770 1.00 0.00 C +ATOM 842 CD LYS 87 -0.339 16.358 -12.175 1.00 0.00 C +ATOM 843 CE LYS 87 -0.969 17.451 -13.037 1.00 0.00 C +ATOM 844 NZ LYS 87 -2.393 17.182 -13.400 1.00 0.00 N +ATOM 845 HZ1 LYS 87 -2.452 16.293 -13.936 1.00 0.00 H +ATOM 846 HZ2 LYS 87 -2.755 17.963 -13.983 1.00 0.00 H +ATOM 847 HZ3 LYS 87 -2.963 17.103 -12.533 1.00 0.00 H +ATOM 848 C LYS 87 1.040 16.708 -8.332 1.00 0.00 C +ATOM 849 O LYS 87 0.731 17.854 -7.986 1.00 0.00 O +ATOM 850 N ILE 88 2.283 16.327 -8.658 1.00 0.00 N +ATOM 851 H ILE 88 2.457 15.386 -8.887 1.00 0.00 H +ATOM 852 CA ILE 88 3.482 17.188 -8.713 1.00 0.00 C +ATOM 853 CB ILE 88 4.201 17.387 -7.307 1.00 0.00 C +ATOM 854 CG2 ILE 88 3.553 18.566 -6.567 1.00 0.00 C +ATOM 855 CG1 ILE 88 4.193 16.098 -6.458 1.00 0.00 C +ATOM 856 CD1 ILE 88 5.455 15.866 -5.615 1.00 0.00 C +ATOM 857 C ILE 88 4.440 16.536 -9.731 1.00 0.00 C +ATOM 858 O ILE 88 5.156 17.231 -10.464 1.00 0.00 O +ATOM 859 N LYS 89 4.408 15.193 -9.760 1.00 0.00 N +ATOM 860 H LYS 89 3.803 14.702 -9.161 1.00 0.00 H +ATOM 861 CA LYS 89 5.222 14.329 -10.639 1.00 0.00 C +ATOM 862 CB LYS 89 6.354 13.662 -9.836 1.00 0.00 C +ATOM 863 CG LYS 89 7.475 14.608 -9.408 1.00 0.00 C +ATOM 864 CD LYS 89 8.521 13.901 -8.564 1.00 0.00 C +ATOM 865 CE LYS 89 9.598 14.874 -8.108 1.00 0.00 C +ATOM 866 NZ LYS 89 10.627 14.218 -7.256 1.00 0.00 N +ATOM 867 HZ1 LYS 89 11.095 13.464 -7.797 1.00 0.00 H +ATOM 868 HZ2 LYS 89 11.335 14.922 -6.964 1.00 0.00 H +ATOM 869 HZ3 LYS 89 10.174 13.812 -6.412 1.00 0.00 H +ATOM 870 C LYS 89 4.327 13.232 -11.240 1.00 0.00 C +ATOM 871 O LYS 89 3.227 12.989 -10.729 1.00 0.00 O +ATOM 872 N THR 90 4.792 12.602 -12.331 1.00 0.00 N +ATOM 873 H THR 90 5.654 12.863 -12.722 1.00 0.00 H +ATOM 874 CA THR 90 4.082 11.503 -13.021 1.00 0.00 C +ATOM 875 CB THR 90 3.618 11.894 -14.465 1.00 0.00 C +ATOM 876 OG1 THR 90 4.719 12.455 -15.194 1.00 0.00 O +ATOM 877 HG1 THR 90 5.019 13.267 -14.778 1.00 0.00 H +ATOM 878 CG2 THR 90 2.477 12.903 -14.411 1.00 0.00 C +ATOM 879 C THR 90 4.999 10.252 -13.084 1.00 0.00 C +ATOM 880 O THR 90 6.186 10.388 -13.412 1.00 0.00 O +ATOM 881 N PRO 91 4.475 9.025 -12.758 1.00 0.00 N +ATOM 882 CD PRO 91 3.138 8.724 -12.202 1.00 0.00 C +ATOM 883 CA PRO 91 5.266 7.774 -12.785 1.00 0.00 C +ATOM 884 CB PRO 91 4.294 6.745 -12.194 1.00 0.00 C +ATOM 885 CG PRO 91 3.431 7.545 -11.315 1.00 0.00 C +ATOM 886 C PRO 91 5.738 7.338 -14.189 1.00 0.00 C +ATOM 887 O PRO 91 6.632 6.491 -14.317 1.00 0.00 O +ATOM 888 N LYS 92 5.137 7.952 -15.217 1.00 0.00 N +ATOM 889 H LYS 92 4.451 8.634 -15.049 1.00 0.00 H +ATOM 890 CA LYS 92 5.430 7.686 -16.637 1.00 0.00 C +ATOM 891 CB LYS 92 4.140 7.808 -17.487 1.00 0.00 C +ATOM 892 CG LYS 92 3.271 9.068 -17.277 1.00 0.00 C +ATOM 893 CD LYS 92 2.042 9.050 -18.179 1.00 0.00 C +ATOM 894 CE LYS 92 1.167 10.287 -17.988 1.00 0.00 C +ATOM 895 NZ LYS 92 1.801 11.548 -18.477 1.00 0.00 N +ATOM 896 HZ1 LYS 92 1.154 12.346 -18.317 1.00 0.00 H +ATOM 897 HZ2 LYS 92 2.001 11.464 -19.494 1.00 0.00 H +ATOM 898 HZ3 LYS 92 2.689 11.712 -17.961 1.00 0.00 H +ATOM 899 C LYS 92 6.582 8.553 -17.204 1.00 0.00 C +ATOM 900 O LYS 92 7.129 8.245 -18.273 1.00 0.00 O +ATOM 901 N GLU 93 6.951 9.602 -16.454 1.00 0.00 N +ATOM 902 H GLU 93 6.500 9.786 -15.601 1.00 0.00 H +ATOM 903 CA GLU 93 8.025 10.545 -16.822 1.00 0.00 C +ATOM 904 CB GLU 93 7.508 11.994 -16.814 1.00 0.00 C +ATOM 905 CG GLU 93 6.539 12.330 -17.946 1.00 0.00 C +ATOM 906 CD GLU 93 6.109 13.785 -17.938 1.00 0.00 C +ATOM 907 OE1 GLU 93 6.797 14.614 -18.572 1.00 0.00 O +ATOM 908 OE2 GLU 93 5.082 14.101 -17.301 1.00 0.00 O +ATOM 909 C GLU 93 9.260 10.435 -15.912 1.00 0.00 C +ATOM 910 O GLU 93 10.390 10.614 -16.385 1.00 0.00 O +ATOM 911 N VAL 94 9.037 10.132 -14.623 1.00 0.00 N +ATOM 912 H VAL 94 8.121 9.984 -14.302 1.00 0.00 H +ATOM 913 CA VAL 94 10.107 9.995 -13.610 1.00 0.00 C +ATOM 914 CB VAL 94 9.681 10.680 -12.229 1.00 0.00 C +ATOM 915 CG1 VAL 94 8.584 9.888 -11.495 1.00 0.00 C +ATOM 916 CG2 VAL 94 10.900 10.946 -11.330 1.00 0.00 C +ATOM 917 C VAL 94 10.584 8.526 -13.435 1.00 0.00 C +ATOM 918 O VAL 94 9.784 7.593 -13.572 1.00 0.00 O +ATOM 919 N ASN 95 11.881 8.362 -13.137 1.00 0.00 N +ATOM 920 H ASN 95 12.470 9.143 -13.046 1.00 0.00 H +ATOM 921 CA ASN 95 12.530 7.054 -12.925 1.00 0.00 C +ATOM 922 CB ASN 95 13.771 6.914 -13.826 1.00 0.00 C +ATOM 923 CG ASN 95 13.430 6.913 -15.313 1.00 0.00 C +ATOM 924 OD1 ASN 95 13.201 5.858 -15.910 1.00 0.00 O +ATOM 925 ND2 ASN 95 13.411 8.097 -15.920 1.00 0.00 N +ATOM 926 HD21 ASN 95 13.193 8.114 -16.875 1.00 0.00 H +ATOM 927 HD22 ASN 95 13.613 8.904 -15.401 1.00 0.00 H +ATOM 928 C ASN 95 12.937 6.893 -11.451 1.00 0.00 C +ATOM 929 O ASN 95 13.123 7.897 -10.752 1.00 0.00 O +ATOM 930 N ALA 96 13.071 5.639 -10.997 1.00 0.00 N +ATOM 931 H ALA 96 12.913 4.876 -11.595 1.00 0.00 H +ATOM 932 CA ALA 96 13.454 5.299 -9.614 1.00 0.00 C +ATOM 933 CB ALA 96 12.561 4.171 -9.085 1.00 0.00 C +ATOM 934 C ALA 96 14.949 4.928 -9.498 1.00 0.00 C +ATOM 935 O ALA 96 15.336 4.095 -8.664 1.00 0.00 O +ATOM 936 N ASP 97 15.776 5.590 -10.320 1.00 0.00 N +ATOM 937 H ASP 97 15.420 6.258 -10.946 1.00 0.00 H +ATOM 938 CA ASP 97 17.239 5.396 -10.368 1.00 0.00 C +ATOM 939 CB ASP 97 17.761 5.631 -11.797 1.00 0.00 C +ATOM 940 CG ASP 97 17.269 4.582 -12.790 1.00 0.00 C +ATOM 941 OD1 ASP 97 17.964 3.558 -12.974 1.00 0.00 O +ATOM 942 OD2 ASP 97 16.198 4.789 -13.401 1.00 0.00 O +ATOM 943 C ASP 97 17.956 6.336 -9.380 1.00 0.00 C +ATOM 944 O ASP 97 19.122 6.109 -9.029 1.00 0.00 O +ATOM 945 N ASP 98 17.223 7.360 -8.922 1.00 0.00 N +ATOM 946 H ASP 98 16.293 7.478 -9.216 1.00 0.00 H +ATOM 947 CA ASP 98 17.709 8.376 -7.970 1.00 0.00 C +ATOM 948 CB ASP 98 17.401 9.788 -8.496 1.00 0.00 C +ATOM 949 CG ASP 98 18.169 10.129 -9.770 1.00 0.00 C +ATOM 950 OD1 ASP 98 17.645 9.868 -10.876 1.00 0.00 O +ATOM 951 OD2 ASP 98 19.290 10.676 -9.668 1.00 0.00 O +ATOM 952 C ASP 98 17.080 8.181 -6.578 1.00 0.00 C +ATOM 953 O ASP 98 17.630 8.657 -5.575 1.00 0.00 O +ATOM 954 N TYR 99 15.951 7.457 -6.533 1.00 0.00 N +ATOM 955 H TYR 99 15.567 7.088 -7.359 1.00 0.00 H +ATOM 956 CA TYR 99 15.203 7.154 -5.296 1.00 0.00 C +ATOM 957 CB TYR 99 13.687 7.044 -5.590 1.00 0.00 C +ATOM 958 CG TYR 99 13.006 8.279 -6.192 1.00 0.00 C +ATOM 959 CD1 TYR 99 12.400 9.258 -5.364 1.00 0.00 C +ATOM 960 CE1 TYR 99 11.734 10.385 -5.921 1.00 0.00 C +ATOM 961 CD2 TYR 99 12.926 8.460 -7.596 1.00 0.00 C +ATOM 962 CE2 TYR 99 12.262 9.584 -8.159 1.00 0.00 C +ATOM 963 CZ TYR 99 11.671 10.536 -7.316 1.00 0.00 C +ATOM 964 OH TYR 99 11.026 11.622 -7.862 1.00 0.00 O +ATOM 965 HH TYR 99 10.672 12.183 -7.168 1.00 0.00 H +ATOM 966 C TYR 99 15.706 5.849 -4.654 1.00 0.00 C +ATOM 967 O TYR 99 16.157 4.946 -5.370 1.00 0.00 O +ATOM 968 N GLN 100 15.624 5.766 -3.319 1.00 0.00 N +ATOM 969 H GLN 100 15.244 6.506 -2.796 1.00 0.00 H +ATOM 970 CA GLN 100 16.080 4.597 -2.545 1.00 0.00 C +ATOM 971 CB GLN 100 17.001 5.040 -1.383 1.00 0.00 C +ATOM 972 CG GLN 100 18.355 5.662 -1.795 1.00 0.00 C +ATOM 973 CD GLN 100 19.503 4.655 -1.868 1.00 0.00 C +ATOM 974 OE1 GLN 100 20.297 4.533 -0.936 1.00 0.00 O +ATOM 975 NE2 GLN 100 19.591 3.935 -2.982 1.00 0.00 N +ATOM 976 HE21 GLN 100 20.322 3.285 -3.046 1.00 0.00 H +ATOM 977 HE22 GLN 100 18.934 4.075 -3.697 1.00 0.00 H +ATOM 978 C GLN 100 14.958 3.686 -2.015 1.00 0.00 C +ATOM 979 O GLN 100 15.004 2.471 -2.229 1.00 0.00 O +ATOM 980 N ILE 101 13.959 4.278 -1.343 1.00 0.00 N +ATOM 981 H ILE 101 13.955 5.252 -1.221 1.00 0.00 H +ATOM 982 CA ILE 101 12.816 3.548 -0.749 1.00 0.00 C +ATOM 983 CB ILE 101 12.674 3.830 0.826 1.00 0.00 C +ATOM 984 CG2 ILE 101 11.821 2.725 1.516 1.00 0.00 C +ATOM 985 CG1 ILE 101 14.050 4.050 1.523 1.00 0.00 C +ATOM 986 CD1 ILE 101 15.094 2.862 1.581 1.00 0.00 C +ATOM 987 C ILE 101 11.502 3.912 -1.474 1.00 0.00 C +ATOM 988 O ILE 101 11.352 5.039 -1.953 1.00 0.00 O +ATOM 989 N PHE 102 10.605 2.925 -1.616 1.00 0.00 N +ATOM 990 H PHE 102 10.804 2.022 -1.283 1.00 0.00 H +ATOM 991 CA PHE 102 9.289 3.095 -2.259 1.00 0.00 C +ATOM 992 CB PHE 102 9.207 2.270 -3.581 1.00 0.00 C +ATOM 993 CG PHE 102 8.023 2.616 -4.496 1.00 0.00 C +ATOM 994 CD1 PHE 102 8.136 3.626 -5.480 1.00 0.00 C +ATOM 995 CD2 PHE 102 6.803 1.902 -4.401 1.00 0.00 C +ATOM 996 CE1 PHE 102 7.055 3.922 -6.354 1.00 0.00 C +ATOM 997 CE2 PHE 102 5.714 2.187 -5.268 1.00 0.00 C +ATOM 998 CZ PHE 102 5.841 3.201 -6.246 1.00 0.00 C +ATOM 999 C PHE 102 8.189 2.644 -1.282 1.00 0.00 C +ATOM 1000 O PHE 102 8.323 1.599 -0.634 1.00 0.00 O +ATOM 1001 N PHE 103 7.136 3.462 -1.164 1.00 0.00 N +ATOM 1002 H PHE 103 7.104 4.305 -1.663 1.00 0.00 H +ATOM 1003 CA PHE 103 5.969 3.187 -0.311 1.00 0.00 C +ATOM 1004 CB PHE 103 5.937 4.110 0.939 1.00 0.00 C +ATOM 1005 CG PHE 103 6.683 3.562 2.152 1.00 0.00 C +ATOM 1006 CD1 PHE 103 5.974 2.944 3.209 1.00 0.00 C +ATOM 1007 CD2 PHE 103 8.089 3.683 2.264 1.00 0.00 C +ATOM 1008 CE1 PHE 103 6.650 2.453 4.360 1.00 0.00 C +ATOM 1009 CE2 PHE 103 8.777 3.197 3.406 1.00 0.00 C +ATOM 1010 CZ PHE 103 8.056 2.580 4.458 1.00 0.00 C +ATOM 1011 C PHE 103 4.683 3.321 -1.131 1.00 0.00 C +ATOM 1012 O PHE 103 4.492 4.323 -1.826 1.00 0.00 O +ATOM 1013 N ALA 104 3.841 2.281 -1.088 1.00 0.00 N +ATOM 1014 H ALA 104 4.057 1.484 -0.555 1.00 0.00 H +ATOM 1015 CA ALA 104 2.561 2.238 -1.812 1.00 0.00 C +ATOM 1016 CB ALA 104 2.486 0.983 -2.696 1.00 0.00 C +ATOM 1017 C ALA 104 1.393 2.278 -0.815 1.00 0.00 C +ATOM 1018 O ALA 104 1.153 1.300 -0.093 1.00 0.00 O +ATOM 1019 N SER 105 0.706 3.428 -0.758 1.00 0.00 N +ATOM 1020 H SER 105 0.948 4.186 -1.334 1.00 0.00 H +ATOM 1021 CA SER 105 -0.437 3.648 0.143 1.00 0.00 C +ATOM 1022 CB SER 105 -0.371 5.041 0.783 1.00 0.00 C +ATOM 1023 OG SER 105 -0.276 6.062 -0.199 1.00 0.00 O +ATOM 1024 HG SER 105 -1.063 6.074 -0.750 1.00 0.00 H +ATOM 1025 C SER 105 -1.805 3.430 -0.511 1.00 0.00 C +ATOM 1026 O SER 105 -2.137 4.074 -1.519 1.00 0.00 O +ATOM 1027 N ALA 106 -2.565 2.484 0.057 1.00 0.00 N +ATOM 1028 H ALA 106 -2.221 1.980 0.828 1.00 0.00 H +ATOM 1029 CA ALA 106 -3.924 2.102 -0.373 1.00 0.00 C +ATOM 1030 CB ALA 106 -3.912 1.487 -1.784 1.00 0.00 C +ATOM 1031 C ALA 106 -4.482 1.100 0.642 1.00 0.00 C +ATOM 1032 O ALA 106 -3.820 0.106 0.968 1.00 0.00 O +ATOM 1033 N GLY 107 -5.678 1.391 1.157 1.00 0.00 N +ATOM 1034 H GLY 107 -6.167 2.202 0.892 1.00 0.00 H +ATOM 1035 CA GLY 107 -6.326 0.530 2.135 1.00 0.00 C +ATOM 1036 C GLY 107 -7.833 0.582 2.005 1.00 0.00 C +ATOM 1037 O GLY 107 -8.547 0.705 3.007 1.00 0.00 O +ATOM 1038 N HIS 108 -8.301 0.485 0.755 1.00 0.00 N +ATOM 1039 H HIS 108 -7.664 0.366 0.017 1.00 0.00 H +ATOM 1040 CA HIS 108 -9.724 0.542 0.388 1.00 0.00 C +ATOM 1041 CB HIS 108 -10.037 1.877 -0.331 1.00 0.00 C +ATOM 1042 CG HIS 108 -8.852 2.792 -0.469 1.00 0.00 C +ATOM 1043 CD2 HIS 108 -7.997 3.006 -1.500 1.00 0.00 C +ATOM 1044 ND1 HIS 108 -8.413 3.596 0.561 1.00 0.00 N +ATOM 1045 HD1 HIS 108 -8.827 3.668 1.446 1.00 0.00 H +ATOM 1046 CE1 HIS 108 -7.339 4.262 0.174 1.00 0.00 C +ATOM 1047 NE2 HIS 108 -7.067 3.922 -1.073 1.00 0.00 N +ATOM 1048 HE2 HIS 108 -6.321 4.268 -1.606 1.00 0.00 H +ATOM 1049 C HIS 108 -10.124 -0.652 -0.493 1.00 0.00 C +ATOM 1050 O HIS 108 -10.667 -1.637 0.021 1.00 0.00 O +ATOM 1051 N GLY 109 -9.856 -0.561 -1.802 1.00 0.00 N +ATOM 1052 H GLY 109 -9.419 0.232 -2.182 1.00 0.00 H +ATOM 1053 CA GLY 109 -10.190 -1.633 -2.730 1.00 0.00 C +ATOM 1054 C GLY 109 -10.481 -1.204 -4.156 1.00 0.00 C +ATOM 1055 O GLY 109 -11.421 -1.724 -4.771 1.00 0.00 O +ATOM 1056 N THR 110 -9.678 -0.267 -4.676 1.00 0.00 N +ATOM 1057 H THR 110 -8.954 0.097 -4.123 1.00 0.00 H +ATOM 1058 CA THR 110 -9.816 0.256 -6.046 1.00 0.00 C +ATOM 1059 CB THR 110 -9.983 1.838 -6.065 1.00 0.00 C +ATOM 1060 OG1 THR 110 -10.111 2.301 -7.416 1.00 0.00 O +ATOM 1061 HG1 THR 110 -9.316 2.097 -7.914 1.00 0.00 H +ATOM 1062 CG2 THR 110 -8.807 2.561 -5.382 1.00 0.00 C +ATOM 1063 C THR 110 -8.672 -0.219 -6.975 1.00 0.00 C +ATOM 1064 O THR 110 -8.920 -0.976 -7.920 1.00 0.00 O +ATOM 1065 N LEU 111 -7.433 0.199 -6.654 1.00 0.00 N +ATOM 1066 H LEU 111 -7.293 0.737 -5.848 1.00 0.00 H +ATOM 1067 CA LEU 111 -6.172 -0.093 -7.377 1.00 0.00 C +ATOM 1068 CB LEU 111 -5.612 -1.499 -7.002 1.00 0.00 C +ATOM 1069 CG LEU 111 -5.294 -2.064 -5.586 1.00 0.00 C +ATOM 1070 CD1 LEU 111 -4.100 -1.355 -4.923 1.00 0.00 C +ATOM 1071 CD2 LEU 111 -6.516 -2.108 -4.650 1.00 0.00 C +ATOM 1072 C LEU 111 -6.180 0.127 -8.903 1.00 0.00 C +ATOM 1073 O LEU 111 -5.550 1.074 -9.382 1.00 0.00 O +ATOM 1074 N PHE 112 -6.937 -0.709 -9.638 1.00 0.00 N +ATOM 1075 H PHE 112 -7.440 -1.422 -9.188 1.00 0.00 H +ATOM 1076 CA PHE 112 -7.098 -0.688 -11.118 1.00 0.00 C +ATOM 1077 CB PHE 112 -8.049 0.459 -11.580 1.00 0.00 C +ATOM 1078 CG PHE 112 -9.528 0.228 -11.274 1.00 0.00 C +ATOM 1079 CD1 PHE 112 -10.127 0.808 -10.133 1.00 0.00 C +ATOM 1080 CD2 PHE 112 -10.342 -0.534 -12.149 1.00 0.00 C +ATOM 1081 CE1 PHE 112 -11.513 0.637 -9.861 1.00 0.00 C +ATOM 1082 CE2 PHE 112 -11.729 -0.714 -11.891 1.00 0.00 C +ATOM 1083 CZ PHE 112 -12.315 -0.127 -10.744 1.00 0.00 C +ATOM 1084 C PHE 112 -5.813 -0.688 -11.974 1.00 0.00 C +ATOM 1085 O PHE 112 -5.620 -1.591 -12.797 1.00 0.00 O +ATOM 1086 N ASP 113 -4.957 0.323 -11.767 1.00 0.00 N +ATOM 1087 H ASP 113 -5.164 1.033 -11.130 1.00 0.00 H +ATOM 1088 CA ASP 113 -3.684 0.503 -12.486 1.00 0.00 C +ATOM 1089 CB ASP 113 -3.528 1.976 -12.912 1.00 0.00 C +ATOM 1090 CG ASP 113 -4.562 2.409 -13.948 1.00 0.00 C +ATOM 1091 OD1 ASP 113 -5.645 2.892 -13.549 1.00 0.00 O +ATOM 1092 OD2 ASP 113 -4.286 2.282 -15.161 1.00 0.00 O +ATOM 1093 C ASP 113 -2.458 0.046 -11.666 1.00 0.00 C +ATOM 1094 O ASP 113 -1.310 0.257 -12.084 1.00 0.00 O +ATOM 1095 N TYR 114 -2.713 -0.618 -10.532 1.00 0.00 N +ATOM 1096 H TYR 114 -3.639 -0.794 -10.255 1.00 0.00 H +ATOM 1097 CA TYR 114 -1.664 -1.126 -9.629 1.00 0.00 C +ATOM 1098 CB TYR 114 -2.051 -0.876 -8.150 1.00 0.00 C +ATOM 1099 CG TYR 114 -1.930 0.555 -7.616 1.00 0.00 C +ATOM 1100 CD1 TYR 114 -0.921 0.892 -6.686 1.00 0.00 C +ATOM 1101 CE1 TYR 114 -0.832 2.199 -6.134 1.00 0.00 C +ATOM 1102 CD2 TYR 114 -2.852 1.567 -7.986 1.00 0.00 C +ATOM 1103 CE2 TYR 114 -2.768 2.876 -7.441 1.00 0.00 C +ATOM 1104 CZ TYR 114 -1.758 3.180 -6.518 1.00 0.00 C +ATOM 1105 OH TYR 114 -1.678 4.447 -5.987 1.00 0.00 O +ATOM 1106 HH TYR 114 -0.962 4.499 -5.350 1.00 0.00 H +ATOM 1107 C TYR 114 -1.260 -2.618 -9.818 1.00 0.00 C +ATOM 1108 O TYR 114 -0.064 -2.919 -9.721 1.00 0.00 O +ATOM 1109 N PRO 115 -2.224 -3.565 -10.089 1.00 0.00 N +ATOM 1110 CD PRO 115 -3.709 -3.498 -10.021 1.00 0.00 C +ATOM 1111 CA PRO 115 -1.791 -4.972 -10.255 1.00 0.00 C +ATOM 1112 CB PRO 115 -3.067 -5.760 -9.930 1.00 0.00 C +ATOM 1113 CG PRO 115 -4.154 -4.874 -10.457 1.00 0.00 C +ATOM 1114 C PRO 115 -1.100 -5.439 -11.571 1.00 0.00 C +ATOM 1115 O PRO 115 0.108 -5.701 -11.563 1.00 0.00 O +ATOM 1116 N LYS 116 -1.870 -5.539 -12.665 1.00 0.00 N +ATOM 1117 H LYS 116 -2.823 -5.307 -12.617 1.00 0.00 H +ATOM 1118 CA LYS 116 -1.378 -5.985 -13.983 1.00 0.00 C +ATOM 1119 CB LYS 116 -2.276 -7.120 -14.546 1.00 0.00 C +ATOM 1120 CG LYS 116 -3.801 -6.879 -14.534 1.00 0.00 C +ATOM 1121 CD LYS 116 -4.555 -8.070 -15.116 1.00 0.00 C +ATOM 1122 CE LYS 116 -6.066 -7.852 -15.115 1.00 0.00 C +ATOM 1123 NZ LYS 116 -6.518 -6.796 -16.070 1.00 0.00 N +ATOM 1124 HZ1 LYS 116 -6.243 -7.062 -17.037 1.00 0.00 H +ATOM 1125 HZ2 LYS 116 -6.074 -5.889 -15.820 1.00 0.00 H +ATOM 1126 HZ3 LYS 116 -7.553 -6.701 -16.018 1.00 0.00 H +ATOM 1127 C LYS 116 -1.149 -4.844 -15.009 1.00 0.00 C +ATOM 1128 O LYS 116 -1.282 -5.050 -16.226 1.00 0.00 O +ATOM 1129 N ALA 117 -0.771 -3.664 -14.499 1.00 0.00 N +ATOM 1130 H ALA 117 -0.655 -3.554 -13.530 1.00 0.00 H +ATOM 1131 CA ALA 117 -0.503 -2.467 -15.315 1.00 0.00 C +ATOM 1132 CB ALA 117 -1.171 -1.260 -14.707 1.00 0.00 C +ATOM 1133 C ALA 117 1.000 -2.211 -15.488 1.00 0.00 C +ATOM 1134 O ALA 117 1.790 -2.545 -14.602 1.00 0.00 O +ATOM 1135 N LYS 118 1.367 -1.592 -16.617 1.00 0.00 N +ATOM 1136 H LYS 118 0.676 -1.311 -17.258 1.00 0.00 H +ATOM 1137 CA LYS 118 2.761 -1.277 -16.993 1.00 0.00 C +ATOM 1138 CB LYS 118 2.846 -0.945 -18.491 1.00 0.00 C +ATOM 1139 CG LYS 118 2.607 -2.129 -19.423 1.00 0.00 C +ATOM 1140 CD LYS 118 2.710 -1.710 -20.886 1.00 0.00 C +ATOM 1141 CE LYS 118 2.475 -2.881 -21.839 1.00 0.00 C +ATOM 1142 NZ LYS 118 3.565 -3.903 -21.809 1.00 0.00 N +ATOM 1143 HZ1 LYS 118 3.342 -4.667 -22.478 1.00 0.00 H +ATOM 1144 HZ2 LYS 118 4.465 -3.457 -22.079 1.00 0.00 H +ATOM 1145 HZ3 LYS 118 3.647 -4.294 -20.849 1.00 0.00 H +ATOM 1146 C LYS 118 3.535 -0.213 -16.192 1.00 0.00 C +ATOM 1147 O LYS 118 4.672 -0.474 -15.795 1.00 0.00 O +ATOM 1148 N ASP 119 2.906 0.940 -15.915 1.00 0.00 N +ATOM 1149 H ASP 119 1.971 1.060 -16.192 1.00 0.00 H +ATOM 1150 CA ASP 119 3.544 2.069 -15.196 1.00 0.00 C +ATOM 1151 CB ASP 119 2.683 3.339 -15.324 1.00 0.00 C +ATOM 1152 CG ASP 119 2.574 3.842 -16.761 1.00 0.00 C +ATOM 1153 OD1 ASP 119 3.429 4.653 -17.180 1.00 0.00 O +ATOM 1154 OD2 ASP 119 1.624 3.439 -17.467 1.00 0.00 O +ATOM 1155 C ASP 119 3.924 1.846 -13.718 1.00 0.00 C +ATOM 1156 O ASP 119 5.068 2.129 -13.335 1.00 0.00 O +ATOM 1157 N LEU 120 2.987 1.328 -12.910 1.00 0.00 N +ATOM 1158 H LEU 120 2.092 1.120 -13.258 1.00 0.00 H +ATOM 1159 CA LEU 120 3.224 1.041 -11.482 1.00 0.00 C +ATOM 1160 CB LEU 120 1.907 0.919 -10.695 1.00 0.00 C +ATOM 1161 CG LEU 120 1.403 2.220 -10.034 1.00 0.00 C +ATOM 1162 CD1 LEU 120 -0.102 2.343 -10.173 1.00 0.00 C +ATOM 1163 CD2 LEU 120 1.814 2.314 -8.551 1.00 0.00 C +ATOM 1164 C LEU 120 4.161 -0.150 -11.232 1.00 0.00 C +ATOM 1165 O LEU 120 4.967 -0.124 -10.293 1.00 0.00 O +ATOM 1166 N GLN 121 4.044 -1.182 -12.080 1.00 0.00 N +ATOM 1167 H GLN 121 3.365 -1.162 -12.790 1.00 0.00 H +ATOM 1168 CA GLN 121 4.893 -2.387 -12.018 1.00 0.00 C +ATOM 1169 CB GLN 121 4.336 -3.510 -12.899 1.00 0.00 C +ATOM 1170 CG GLN 121 3.153 -4.259 -12.304 1.00 0.00 C +ATOM 1171 CD GLN 121 2.793 -5.498 -13.102 1.00 0.00 C +ATOM 1172 OE1 GLN 121 3.303 -6.588 -12.840 1.00 0.00 O +ATOM 1173 NE2 GLN 121 1.910 -5.339 -14.081 1.00 0.00 N +ATOM 1174 HE21 GLN 121 1.675 -6.131 -14.609 1.00 0.00 H +ATOM 1175 HE22 GLN 121 1.520 -4.456 -14.243 1.00 0.00 H +ATOM 1176 C GLN 121 6.339 -2.035 -12.420 1.00 0.00 C +ATOM 1177 O GLN 121 7.292 -2.580 -11.851 1.00 0.00 O +ATOM 1178 N ASP 122 6.476 -1.116 -13.392 1.00 0.00 N +ATOM 1179 H ASP 122 5.673 -0.736 -13.819 1.00 0.00 H +ATOM 1180 CA ASP 122 7.774 -0.620 -13.903 1.00 0.00 C +ATOM 1181 CB ASP 122 7.578 0.184 -15.204 1.00 0.00 C +ATOM 1182 CG ASP 122 8.776 0.092 -16.154 1.00 0.00 C +ATOM 1183 OD1 ASP 122 9.687 0.943 -16.054 1.00 0.00 O +ATOM 1184 OD2 ASP 122 8.795 -0.821 -17.008 1.00 0.00 O +ATOM 1185 C ASP 122 8.514 0.240 -12.854 1.00 0.00 C +ATOM 1186 O ASP 122 9.734 0.106 -12.709 1.00 0.00 O +ATOM 1187 N ILE 123 7.771 1.093 -12.126 1.00 0.00 N +ATOM 1188 H ILE 123 6.801 1.150 -12.297 1.00 0.00 H +ATOM 1189 CA ILE 123 8.331 1.975 -11.077 1.00 0.00 C +ATOM 1190 CB ILE 123 7.315 3.149 -10.677 1.00 0.00 C +ATOM 1191 CG2 ILE 123 6.174 2.643 -9.772 1.00 0.00 C +ATOM 1192 CG1 ILE 123 8.070 4.336 -10.046 1.00 0.00 C +ATOM 1193 CD1 ILE 123 7.622 5.717 -10.536 1.00 0.00 C +ATOM 1194 C ILE 123 8.831 1.115 -9.882 1.00 0.00 C +ATOM 1195 O ILE 123 9.872 1.423 -9.287 1.00 0.00 O +ATOM 1196 N ALA 124 8.090 0.037 -9.579 1.00 0.00 N +ATOM 1197 H ALA 124 7.254 -0.146 -10.071 1.00 0.00 H +ATOM 1198 CA ALA 124 8.424 -0.924 -8.508 1.00 0.00 C +ATOM 1199 CB ALA 124 7.253 -1.884 -8.256 1.00 0.00 C +ATOM 1200 C ALA 124 9.687 -1.709 -8.905 1.00 0.00 C +ATOM 1201 O ALA 124 10.585 -1.904 -8.080 1.00 0.00 O +ATOM 1202 N SER 125 9.767 -2.076 -10.194 1.00 0.00 N +ATOM 1203 H SER 125 9.031 -1.847 -10.808 1.00 0.00 H +ATOM 1204 CA SER 125 10.898 -2.821 -10.787 1.00 0.00 C +ATOM 1205 CB SER 125 10.538 -3.312 -12.196 1.00 0.00 C +ATOM 1206 OG SER 125 11.522 -4.192 -12.716 1.00 0.00 O +ATOM 1207 HG SER 125 12.363 -3.738 -12.811 1.00 0.00 H +ATOM 1208 C SER 125 12.174 -1.966 -10.819 1.00 0.00 C +ATOM 1209 O SER 125 13.268 -2.473 -10.548 1.00 0.00 O +ATOM 1210 N GLU 126 12.002 -0.667 -11.110 1.00 0.00 N +ATOM 1211 H GLU 126 11.099 -0.325 -11.292 1.00 0.00 H +ATOM 1212 CA GLU 126 13.094 0.323 -11.170 1.00 0.00 C +ATOM 1213 CB GLU 126 12.615 1.634 -11.805 1.00 0.00 C +ATOM 1214 CG GLU 126 12.484 1.589 -13.324 1.00 0.00 C +ATOM 1215 CD GLU 126 12.008 2.905 -13.910 1.00 0.00 C +ATOM 1216 OE1 GLU 126 12.862 3.756 -14.236 1.00 0.00 O +ATOM 1217 OE2 GLU 126 10.780 3.088 -14.047 1.00 0.00 O +ATOM 1218 C GLU 126 13.696 0.596 -9.784 1.00 0.00 C +ATOM 1219 O GLU 126 14.915 0.749 -9.666 1.00 0.00 O +ATOM 1220 N ILE 127 12.841 0.648 -8.748 1.00 0.00 N +ATOM 1221 H ILE 127 11.874 0.533 -8.905 1.00 0.00 H +ATOM 1222 CA ILE 127 13.280 0.884 -7.359 1.00 0.00 C +ATOM 1223 CB ILE 127 12.095 1.429 -6.432 1.00 0.00 C +ATOM 1224 CG2 ILE 127 11.076 0.338 -6.099 1.00 0.00 C +ATOM 1225 CG1 ILE 127 12.635 2.111 -5.159 1.00 0.00 C +ATOM 1226 CD1 ILE 127 12.331 3.610 -5.056 1.00 0.00 C +ATOM 1227 C ILE 127 14.066 -0.310 -6.756 1.00 0.00 C +ATOM 1228 O ILE 127 15.106 -0.088 -6.134 1.00 0.00 O +ATOM 1229 N TYR 128 13.563 -1.545 -6.915 1.00 0.00 N +ATOM 1230 H TYR 128 12.706 -1.683 -7.379 1.00 0.00 H +ATOM 1231 CA TYR 128 14.273 -2.729 -6.393 1.00 0.00 C +ATOM 1232 CB TYR 128 13.339 -3.948 -6.112 1.00 0.00 C +ATOM 1233 CG TYR 128 12.650 -4.693 -7.263 1.00 0.00 C +ATOM 1234 CD1 TYR 128 11.249 -4.654 -7.397 1.00 0.00 C +ATOM 1235 CE1 TYR 128 10.582 -5.419 -8.383 1.00 0.00 C +ATOM 1236 CD2 TYR 128 13.377 -5.524 -8.158 1.00 0.00 C +ATOM 1237 CE2 TYR 128 12.717 -6.294 -9.150 1.00 0.00 C +ATOM 1238 CZ TYR 128 11.320 -6.235 -9.252 1.00 0.00 C +ATOM 1239 OH TYR 128 10.668 -6.983 -10.204 1.00 0.00 O +ATOM 1240 HH TYR 128 11.302 -7.503 -10.701 1.00 0.00 H +ATOM 1241 C TYR 128 15.567 -3.135 -7.134 1.00 0.00 C +ATOM 1242 O TYR 128 16.532 -3.554 -6.491 1.00 0.00 O +ATOM 1243 N ALA 129 15.569 -2.995 -8.468 1.00 0.00 N +ATOM 1244 H ALA 129 14.772 -2.646 -8.929 1.00 0.00 H +ATOM 1245 CA ALA 129 16.713 -3.340 -9.342 1.00 0.00 C +ATOM 1246 CB ALA 129 16.250 -3.437 -10.792 1.00 0.00 C +ATOM 1247 C ALA 129 17.974 -2.455 -9.250 1.00 0.00 C +ATOM 1248 O ALA 129 19.086 -2.987 -9.162 1.00 0.00 O +ATOM 1249 N ASN 130 17.791 -1.126 -9.267 1.00 0.00 N +ATOM 1250 H ASN 130 16.884 -0.753 -9.323 1.00 0.00 H +ATOM 1251 CA ASN 130 18.896 -0.144 -9.203 1.00 0.00 C +ATOM 1252 CB ASN 130 18.977 0.708 -10.499 1.00 0.00 C +ATOM 1253 CG ASN 130 17.607 1.090 -11.063 1.00 0.00 C +ATOM 1254 OD1 ASN 130 17.025 2.107 -10.683 1.00 0.00 O +ATOM 1255 ND2 ASN 130 17.094 0.273 -11.978 1.00 0.00 N +ATOM 1256 HD21 ASN 130 16.217 0.502 -12.350 1.00 0.00 H +ATOM 1257 HD22 ASN 130 17.602 -0.522 -12.249 1.00 0.00 H +ATOM 1258 C ASN 130 18.898 0.764 -7.962 1.00 0.00 C +ATOM 1259 O ASN 130 19.955 1.276 -7.570 1.00 0.00 O +ATOM 1260 N GLY 131 17.726 0.929 -7.339 1.00 0.00 N +ATOM 1261 H GLY 131 16.913 0.482 -7.661 1.00 0.00 H +ATOM 1262 CA GLY 131 17.584 1.775 -6.156 1.00 0.00 C +ATOM 1263 C GLY 131 17.851 1.099 -4.823 1.00 0.00 C +ATOM 1264 O GLY 131 19.011 0.976 -4.413 1.00 0.00 O +ATOM 1265 N GLY 132 16.779 0.666 -4.157 1.00 0.00 N +ATOM 1266 H GLY 132 15.883 0.798 -4.529 1.00 0.00 H +ATOM 1267 CA GLY 132 16.904 0.008 -2.867 1.00 0.00 C +ATOM 1268 C GLY 132 15.771 -0.941 -2.515 1.00 0.00 C +ATOM 1269 O GLY 132 15.341 -1.738 -3.358 1.00 0.00 O +ATOM 1270 N VAL 133 15.299 -0.842 -1.266 1.00 0.00 N +ATOM 1271 H VAL 133 15.694 -0.170 -0.669 1.00 0.00 H +ATOM 1272 CA VAL 133 14.214 -1.671 -0.706 1.00 0.00 C +ATOM 1273 CB VAL 133 14.471 -2.036 0.807 1.00 0.00 C +ATOM 1274 CG1 VAL 133 15.577 -3.078 0.908 1.00 0.00 C +ATOM 1275 CG2 VAL 133 14.852 -0.794 1.645 1.00 0.00 C +ATOM 1276 C VAL 133 12.789 -1.100 -0.895 1.00 0.00 C +ATOM 1277 O VAL 133 12.599 0.123 -0.841 1.00 0.00 O +ATOM 1278 N VAL 134 11.817 -1.994 -1.135 1.00 0.00 N +ATOM 1279 H VAL 134 12.024 -2.953 -1.177 1.00 0.00 H +ATOM 1280 CA VAL 134 10.400 -1.634 -1.349 1.00 0.00 C +ATOM 1281 CB VAL 134 9.809 -2.268 -2.677 1.00 0.00 C +ATOM 1282 CG1 VAL 134 8.659 -1.410 -3.233 1.00 0.00 C +ATOM 1283 CG2 VAL 134 10.894 -2.438 -3.739 1.00 0.00 C +ATOM 1284 C VAL 134 9.536 -2.077 -0.145 1.00 0.00 C +ATOM 1285 O VAL 134 9.651 -3.216 0.332 1.00 0.00 O +ATOM 1286 N ALA 135 8.724 -1.138 0.359 1.00 0.00 N +ATOM 1287 H ALA 135 8.721 -0.234 -0.018 1.00 0.00 H +ATOM 1288 CA ALA 135 7.795 -1.351 1.481 1.00 0.00 C +ATOM 1289 CB ALA 135 8.253 -0.569 2.721 1.00 0.00 C +ATOM 1290 C ALA 135 6.414 -0.869 1.019 1.00 0.00 C +ATOM 1291 O ALA 135 6.298 0.243 0.506 1.00 0.00 O +ATOM 1292 N ALA 136 5.394 -1.725 1.150 1.00 0.00 N +ATOM 1293 H ALA 136 5.540 -2.617 1.533 1.00 0.00 H +ATOM 1294 CA ALA 136 4.010 -1.412 0.744 1.00 0.00 C +ATOM 1295 CB ALA 136 3.626 -2.205 -0.498 1.00 0.00 C +ATOM 1296 C ALA 136 3.023 -1.693 1.878 1.00 0.00 C +ATOM 1297 O ALA 136 3.213 -2.653 2.627 1.00 0.00 O +ATOM 1298 N VAL 137 1.978 -0.858 1.992 1.00 0.00 N +ATOM 1299 H VAL 137 1.867 -0.112 1.363 1.00 0.00 H +ATOM 1300 CA VAL 137 0.940 -0.983 3.037 1.00 0.00 C +ATOM 1301 CB VAL 137 0.779 0.336 3.896 1.00 0.00 C +ATOM 1302 CG1 VAL 137 1.819 0.365 4.986 1.00 0.00 C +ATOM 1303 CG2 VAL 137 0.908 1.603 3.035 1.00 0.00 C +ATOM 1304 C VAL 137 -0.439 -1.472 2.540 1.00 0.00 C +ATOM 1305 O VAL 137 -0.974 -0.957 1.547 1.00 0.00 O +ATOM 1306 N CYS 138 -0.967 -2.505 3.224 1.00 0.00 N +ATOM 1307 H CYS 138 -0.468 -2.884 3.979 1.00 0.00 H +ATOM 1308 CA CYS 138 -2.276 -3.175 2.978 1.00 0.00 C +ATOM 1309 CB CYS 138 -3.438 -2.276 3.439 1.00 0.00 C +ATOM 1310 SG CYS 138 -5.071 -3.048 3.427 1.00 0.00 S +ATOM 1311 C CYS 138 -2.522 -3.731 1.555 1.00 0.00 C +ATOM 1312 O CYS 138 -2.296 -4.923 1.312 1.00 0.00 O +ATOM 1313 N HIS 139 -3.039 -2.878 0.662 1.00 0.00 N +ATOM 1314 H HIS 139 -3.246 -1.959 0.942 1.00 0.00 H +ATOM 1315 CA HIS 139 -3.322 -3.170 -0.751 1.00 0.00 C +ATOM 1316 CB HIS 139 -4.312 -2.150 -1.318 1.00 0.00 C +ATOM 1317 CG HIS 139 -5.750 -2.553 -1.162 1.00 0.00 C +ATOM 1318 CD2 HIS 139 -6.764 -1.999 -0.453 1.00 0.00 C +ATOM 1319 ND1 HIS 139 -6.283 -3.665 -1.780 1.00 0.00 N +ATOM 1320 HD1 HIS 139 -5.796 -4.279 -2.370 1.00 0.00 H +ATOM 1321 CE1 HIS 139 -7.558 -3.782 -1.457 1.00 0.00 C +ATOM 1322 NE2 HIS 139 -7.874 -2.784 -0.652 1.00 0.00 N +ATOM 1323 HE2 HIS 139 -8.755 -2.642 -0.250 1.00 0.00 H +ATOM 1324 C HIS 139 -2.057 -3.311 -1.605 1.00 0.00 C +ATOM 1325 O HIS 139 -2.041 -4.059 -2.595 1.00 0.00 O +ATOM 1326 N GLY 140 -1.019 -2.558 -1.211 1.00 0.00 N +ATOM 1327 H GLY 140 -1.095 -1.950 -0.442 1.00 0.00 H +ATOM 1328 CA GLY 140 0.283 -2.575 -1.877 1.00 0.00 C +ATOM 1329 C GLY 140 0.847 -3.999 -1.901 1.00 0.00 C +ATOM 1330 O GLY 140 1.367 -4.401 -2.949 1.00 0.00 O +ATOM 1331 N PRO 141 0.781 -4.780 -0.777 1.00 0.00 N +ATOM 1332 CD PRO 141 0.694 -4.226 0.594 1.00 0.00 C +ATOM 1333 CA PRO 141 1.260 -6.168 -0.681 1.00 0.00 C +ATOM 1334 CB PRO 141 0.875 -6.546 0.742 1.00 0.00 C +ATOM 1335 CG PRO 141 1.233 -5.337 1.467 1.00 0.00 C +ATOM 1336 C PRO 141 0.568 -7.089 -1.703 1.00 0.00 C +ATOM 1337 O PRO 141 1.199 -8.008 -2.230 1.00 0.00 O +ATOM 1338 N ALA 142 -0.724 -6.833 -1.967 1.00 0.00 N +ATOM 1339 H ALA 142 -1.186 -6.098 -1.506 1.00 0.00 H +ATOM 1340 CA ALA 142 -1.532 -7.603 -2.934 1.00 0.00 C +ATOM 1341 CB ALA 142 -3.012 -7.240 -2.798 1.00 0.00 C +ATOM 1342 C ALA 142 -1.069 -7.365 -4.382 1.00 0.00 C +ATOM 1343 O ALA 142 -0.872 -8.324 -5.133 1.00 0.00 O +ATOM 1344 N ILE 143 -0.897 -6.086 -4.747 1.00 0.00 N +ATOM 1345 H ILE 143 -1.071 -5.369 -4.093 1.00 0.00 H +ATOM 1346 CA ILE 143 -0.454 -5.659 -6.093 1.00 0.00 C +ATOM 1347 CB ILE 143 -0.909 -4.186 -6.447 1.00 0.00 C +ATOM 1348 CG2 ILE 143 -2.412 -4.157 -6.608 1.00 0.00 C +ATOM 1349 CG1 ILE 143 -0.474 -3.148 -5.393 1.00 0.00 C +ATOM 1350 CD1 ILE 143 0.668 -2.219 -5.832 1.00 0.00 C +ATOM 1351 C ILE 143 1.014 -5.882 -6.516 1.00 0.00 C +ATOM 1352 O ILE 143 1.274 -6.226 -7.677 1.00 0.00 O +ATOM 1353 N PHE 144 1.948 -5.719 -5.566 1.00 0.00 N +ATOM 1354 H PHE 144 1.674 -5.510 -4.645 1.00 0.00 H +ATOM 1355 CA PHE 144 3.399 -5.840 -5.814 1.00 0.00 C +ATOM 1356 CB PHE 144 4.210 -5.330 -4.576 1.00 0.00 C +ATOM 1357 CG PHE 144 4.853 -6.416 -3.706 1.00 0.00 C +ATOM 1358 CD1 PHE 144 6.242 -6.660 -3.783 1.00 0.00 C +ATOM 1359 CD2 PHE 144 4.092 -7.163 -2.781 1.00 0.00 C +ATOM 1360 CE1 PHE 144 6.861 -7.629 -2.955 1.00 0.00 C +ATOM 1361 CE2 PHE 144 4.698 -8.136 -1.945 1.00 0.00 C +ATOM 1362 CZ PHE 144 6.088 -8.369 -2.034 1.00 0.00 C +ATOM 1363 C PHE 144 3.936 -7.179 -6.363 1.00 0.00 C +ATOM 1364 O PHE 144 4.705 -7.166 -7.325 1.00 0.00 O +ATOM 1365 N ASP 145 3.500 -8.311 -5.793 1.00 0.00 N +ATOM 1366 H ASP 145 2.854 -8.276 -5.054 1.00 0.00 H +ATOM 1367 CA ASP 145 3.949 -9.654 -6.224 1.00 0.00 C +ATOM 1368 CB ASP 145 3.879 -10.675 -5.055 1.00 0.00 C +ATOM 1369 CG ASP 145 2.507 -10.741 -4.380 1.00 0.00 C +ATOM 1370 OD1 ASP 145 1.662 -11.551 -4.817 1.00 0.00 O +ATOM 1371 OD2 ASP 145 2.291 -10.003 -3.396 1.00 0.00 O +ATOM 1372 C ASP 145 3.285 -10.193 -7.515 1.00 0.00 C +ATOM 1373 O ASP 145 2.135 -10.648 -7.493 1.00 0.00 O +ATOM 1374 N GLY 146 4.016 -10.092 -8.630 1.00 0.00 N +ATOM 1375 H GLY 146 4.917 -9.700 -8.617 1.00 0.00 H +ATOM 1376 CA GLY 146 3.523 -10.553 -9.922 1.00 0.00 C +ATOM 1377 C GLY 146 4.447 -10.219 -11.082 1.00 0.00 C +ATOM 1378 O GLY 146 4.180 -10.633 -12.217 1.00 0.00 O +ATOM 1379 N LEU 147 5.524 -9.477 -10.794 1.00 0.00 N +ATOM 1380 H LEU 147 5.666 -9.191 -9.866 1.00 0.00 H +ATOM 1381 CA LEU 147 6.523 -9.057 -11.793 1.00 0.00 C +ATOM 1382 CB LEU 147 6.755 -7.520 -11.743 1.00 0.00 C +ATOM 1383 CG LEU 147 6.892 -6.613 -10.502 1.00 0.00 C +ATOM 1384 CD1 LEU 147 7.901 -5.520 -10.797 1.00 0.00 C +ATOM 1385 CD2 LEU 147 5.552 -6.002 -10.085 1.00 0.00 C +ATOM 1386 C LEU 147 7.863 -9.819 -11.722 1.00 0.00 C +ATOM 1387 O LEU 147 8.158 -10.462 -10.708 1.00 0.00 O +ATOM 1388 N THR 148 8.650 -9.733 -12.807 1.00 0.00 N +ATOM 1389 H THR 148 8.352 -9.201 -13.579 1.00 0.00 H +ATOM 1390 CA THR 148 9.973 -10.378 -12.945 1.00 0.00 C +ATOM 1391 CB THR 148 10.236 -10.858 -14.436 1.00 0.00 C +ATOM 1392 OG1 THR 148 11.574 -11.357 -14.566 1.00 0.00 O +ATOM 1393 HG1 THR 148 11.700 -12.119 -13.998 1.00 0.00 H +ATOM 1394 CG2 THR 148 9.990 -9.736 -15.471 1.00 0.00 C +ATOM 1395 C THR 148 11.115 -9.474 -12.417 1.00 0.00 C +ATOM 1396 O THR 148 11.027 -8.245 -12.524 1.00 0.00 O +ATOM 1397 N ASP 149 12.173 -10.098 -11.876 1.00 0.00 N +ATOM 1398 H ASP 149 12.194 -11.080 -11.848 1.00 0.00 H +ATOM 1399 CA ASP 149 13.346 -9.405 -11.307 1.00 0.00 C +ATOM 1400 CB ASP 149 14.038 -10.316 -10.272 1.00 0.00 C +ATOM 1401 CG ASP 149 14.737 -9.535 -9.155 1.00 0.00 C +ATOM 1402 OD1 ASP 149 15.935 -9.212 -9.308 1.00 0.00 O +ATOM 1403 OD2 ASP 149 14.091 -9.262 -8.119 1.00 0.00 O +ATOM 1404 C ASP 149 14.349 -8.937 -12.388 1.00 0.00 C +ATOM 1405 O ASP 149 14.808 -7.789 -12.343 1.00 0.00 O +ATOM 1406 N LYS 150 14.672 -9.827 -13.338 1.00 0.00 N +ATOM 1407 H LYS 150 14.284 -10.729 -13.324 1.00 0.00 H +ATOM 1408 CA LYS 150 15.605 -9.540 -14.446 1.00 0.00 C +ATOM 1409 CB LYS 150 16.849 -10.472 -14.407 1.00 0.00 C +ATOM 1410 CG LYS 150 16.602 -11.966 -14.110 1.00 0.00 C +ATOM 1411 CD LYS 150 17.908 -12.753 -14.103 1.00 0.00 C +ATOM 1412 CE LYS 150 17.687 -14.235 -13.811 1.00 0.00 C +ATOM 1413 NZ LYS 150 16.979 -14.962 -14.908 1.00 0.00 N +ATOM 1414 HZ1 LYS 150 16.044 -14.532 -15.061 1.00 0.00 H +ATOM 1415 HZ2 LYS 150 16.863 -15.961 -14.643 1.00 0.00 H +ATOM 1416 HZ3 LYS 150 17.538 -14.897 -15.783 1.00 0.00 H +ATOM 1417 C LYS 150 14.915 -9.530 -15.832 1.00 0.00 C +ATOM 1418 O LYS 150 14.577 -8.452 -16.336 1.00 0.00 O +ATOM 1419 N LYS 151 14.716 -10.717 -16.427 1.00 0.00 N +ATOM 1420 H LYS 151 14.999 -11.546 -15.990 1.00 0.00 H +ATOM 1421 CA LYS 151 14.066 -10.903 -17.743 1.00 0.00 C +ATOM 1422 CB LYS 151 15.096 -10.904 -18.909 1.00 0.00 C +ATOM 1423 CG LYS 151 16.380 -11.739 -18.715 1.00 0.00 C +ATOM 1424 CD LYS 151 17.288 -11.646 -19.931 1.00 0.00 C +ATOM 1425 CE LYS 151 18.552 -12.469 -19.740 1.00 0.00 C +ATOM 1426 NZ LYS 151 19.451 -12.387 -20.924 1.00 0.00 N +ATOM 1427 HZ1 LYS 151 20.302 -12.962 -20.754 1.00 0.00 H +ATOM 1428 HZ2 LYS 151 18.953 -12.746 -21.763 1.00 0.00 H +ATOM 1429 HZ3 LYS 151 19.728 -11.397 -21.082 1.00 0.00 H +ATOM 1430 C LYS 151 13.202 -12.179 -17.765 1.00 0.00 C +ATOM 1431 O LYS 151 12.031 -12.130 -18.161 1.00 0.00 O +ATOM 1432 N THR 152 13.799 -13.303 -17.336 1.00 0.00 N +ATOM 1433 H THR 152 14.733 -13.280 -17.033 1.00 0.00 H +ATOM 1434 CA THR 152 13.151 -14.629 -17.274 1.00 0.00 C +ATOM 1435 CB THR 152 13.963 -15.717 -18.113 1.00 0.00 C +ATOM 1436 OG1 THR 152 13.376 -17.014 -17.939 1.00 0.00 O +ATOM 1437 HG1 THR 152 12.474 -17.015 -18.268 1.00 0.00 H +ATOM 1438 CG2 THR 152 15.461 -15.761 -17.733 1.00 0.00 C +ATOM 1439 C THR 152 12.921 -15.075 -15.810 1.00 0.00 C +ATOM 1440 O THR 152 12.152 -16.011 -15.549 1.00 0.00 O +ATOM 1441 N GLY 153 13.551 -14.353 -14.874 1.00 0.00 N +ATOM 1442 H GLY 153 14.113 -13.586 -15.121 1.00 0.00 H +ATOM 1443 CA GLY 153 13.450 -14.646 -13.446 1.00 0.00 C +ATOM 1444 C GLY 153 12.202 -14.138 -12.736 1.00 0.00 C +ATOM 1445 O GLY 153 12.256 -13.124 -12.029 1.00 0.00 O +ATOM 1446 N ARG 154 11.088 -14.854 -12.936 1.00 0.00 N +ATOM 1447 H ARG 154 11.133 -15.642 -13.519 1.00 0.00 H +ATOM 1448 CA ARG 154 9.777 -14.548 -12.341 1.00 0.00 C +ATOM 1449 CB ARG 154 8.699 -14.502 -13.442 1.00 0.00 C +ATOM 1450 CG ARG 154 7.589 -13.457 -13.241 1.00 0.00 C +ATOM 1451 CD ARG 154 6.563 -13.478 -14.374 1.00 0.00 C +ATOM 1452 NE ARG 154 7.107 -12.985 -15.644 1.00 0.00 N +ATOM 1453 HE ARG 154 8.043 -12.695 -15.658 1.00 0.00 H +ATOM 1454 CZ ARG 154 6.427 -12.899 -16.788 1.00 0.00 C +ATOM 1455 NH1 ARG 154 7.032 -12.435 -17.873 1.00 0.00 N +ATOM 1456 HH11 ARG 154 7.990 -12.153 -17.830 1.00 0.00 H +ATOM 1457 HH12 ARG 154 6.529 -12.368 -18.735 1.00 0.00 H +ATOM 1458 NH2 ARG 154 5.153 -13.270 -16.863 1.00 0.00 N +ATOM 1459 HH21 ARG 154 4.686 -13.622 -16.051 1.00 0.00 H +ATOM 1460 HH22 ARG 154 4.661 -13.198 -17.730 1.00 0.00 H +ATOM 1461 C ARG 154 9.457 -15.676 -11.317 1.00 0.00 C +ATOM 1462 O ARG 154 9.846 -16.825 -11.562 1.00 0.00 O +ATOM 1463 N PRO 155 8.784 -15.375 -10.155 1.00 0.00 N +ATOM 1464 CD PRO 155 8.349 -16.574 -9.406 1.00 0.00 C +ATOM 1465 CA PRO 155 8.207 -14.173 -9.504 1.00 0.00 C +ATOM 1466 CB PRO 155 7.429 -14.768 -8.321 1.00 0.00 C +ATOM 1467 CG PRO 155 7.054 -16.117 -8.792 1.00 0.00 C +ATOM 1468 C PRO 155 9.227 -13.112 -9.017 1.00 0.00 C +ATOM 1469 O PRO 155 10.415 -13.198 -9.351 1.00 0.00 O +ATOM 1470 N LEU 156 8.746 -12.137 -8.227 1.00 0.00 N +ATOM 1471 H LEU 156 7.791 -12.136 -7.993 1.00 0.00 H +ATOM 1472 CA LEU 156 9.547 -11.034 -7.657 1.00 0.00 C +ATOM 1473 CB LEU 156 8.620 -9.827 -7.326 1.00 0.00 C +ATOM 1474 CG LEU 156 9.010 -8.347 -7.091 1.00 0.00 C +ATOM 1475 CD1 LEU 156 7.735 -7.551 -6.961 1.00 0.00 C +ATOM 1476 CD2 LEU 156 9.887 -8.089 -5.852 1.00 0.00 C +ATOM 1477 C LEU 156 10.282 -11.489 -6.374 1.00 0.00 C +ATOM 1478 O LEU 156 11.516 -11.437 -6.308 1.00 0.00 O +ATOM 1479 N ILE 157 9.497 -11.930 -5.382 1.00 0.00 N +ATOM 1480 H ILE 157 8.526 -11.980 -5.530 1.00 0.00 H +ATOM 1481 CA ILE 157 9.971 -12.376 -4.059 1.00 0.00 C +ATOM 1482 CB ILE 157 8.920 -11.999 -2.919 1.00 0.00 C +ATOM 1483 CG2 ILE 157 8.933 -10.504 -2.673 1.00 0.00 C +ATOM 1484 CG1 ILE 157 7.486 -12.470 -3.246 1.00 0.00 C +ATOM 1485 CD1 ILE 157 7.086 -13.790 -2.586 1.00 0.00 C +ATOM 1486 C ILE 157 10.383 -13.864 -3.964 1.00 0.00 C +ATOM 1487 O ILE 157 11.411 -14.183 -3.354 1.00 0.00 O +ATOM 1488 N GLU 158 9.576 -14.745 -4.585 1.00 0.00 N +ATOM 1489 H GLU 158 8.784 -14.413 -5.061 1.00 0.00 H +ATOM 1490 CA GLU 158 9.740 -16.226 -4.642 1.00 0.00 C +ATOM 1491 CB GLU 158 11.039 -16.648 -5.362 1.00 0.00 C +ATOM 1492 CG GLU 158 11.102 -16.283 -6.842 1.00 0.00 C +ATOM 1493 CD GLU 158 12.397 -16.721 -7.500 1.00 0.00 C +ATOM 1494 OE1 GLU 158 13.363 -15.928 -7.503 1.00 0.00 O +ATOM 1495 OE2 GLU 158 12.449 -17.857 -8.017 1.00 0.00 O +ATOM 1496 C GLU 158 9.604 -16.994 -3.315 1.00 0.00 C +ATOM 1497 O GLU 158 9.021 -18.084 -3.292 1.00 0.00 O +ATOM 1498 N GLY 159 10.132 -16.419 -2.229 1.00 0.00 N +ATOM 1499 H GLY 159 10.585 -15.555 -2.263 1.00 0.00 H +ATOM 1500 CA GLY 159 10.068 -17.052 -0.917 1.00 0.00 C +ATOM 1501 C GLY 159 10.336 -16.108 0.242 1.00 0.00 C +ATOM 1502 O GLY 159 11.266 -16.341 1.024 1.00 0.00 O +ATOM 1503 N LYS 160 9.521 -15.051 0.344 1.00 0.00 N +ATOM 1504 H LYS 160 8.809 -14.936 -0.321 1.00 0.00 H +ATOM 1505 CA LYS 160 9.622 -14.032 1.404 1.00 0.00 C +ATOM 1506 CB LYS 160 9.932 -12.648 0.801 1.00 0.00 C +ATOM 1507 CG LYS 160 11.326 -12.532 0.185 1.00 0.00 C +ATOM 1508 CD LYS 160 11.644 -11.103 -0.237 1.00 0.00 C +ATOM 1509 CE LYS 160 12.979 -11.003 -0.973 1.00 0.00 C +ATOM 1510 NZ LYS 160 14.169 -11.288 -0.116 1.00 0.00 N +ATOM 1511 HZ1 LYS 160 14.099 -12.254 0.264 1.00 0.00 H +ATOM 1512 HZ2 LYS 160 15.035 -11.201 -0.686 1.00 0.00 H +ATOM 1513 HZ3 LYS 160 14.201 -10.608 0.669 1.00 0.00 H +ATOM 1514 C LYS 160 8.341 -14.018 2.269 1.00 0.00 C +ATOM 1515 O LYS 160 7.886 -15.092 2.681 1.00 0.00 O +ATOM 1516 N SER 161 7.781 -12.830 2.561 1.00 0.00 N +ATOM 1517 H SER 161 8.164 -11.983 2.257 1.00 0.00 H +ATOM 1518 CA SER 161 6.555 -12.664 3.370 1.00 0.00 C +ATOM 1519 CB SER 161 6.905 -12.421 4.847 1.00 0.00 C +ATOM 1520 OG SER 161 7.811 -11.341 4.990 1.00 0.00 O +ATOM 1521 HG SER 161 8.638 -11.520 4.537 1.00 0.00 H +ATOM 1522 C SER 161 5.666 -11.518 2.854 1.00 0.00 C +ATOM 1523 O SER 161 6.165 -10.414 2.590 1.00 0.00 O +ATOM 1524 N ILE 162 4.365 -11.803 2.682 1.00 0.00 N +ATOM 1525 H ILE 162 4.025 -12.704 2.880 1.00 0.00 H +ATOM 1526 CA ILE 162 3.356 -10.830 2.199 1.00 0.00 C +ATOM 1527 CB ILE 162 2.757 -11.209 0.766 1.00 0.00 C +ATOM 1528 CG2 ILE 162 2.265 -9.937 0.026 1.00 0.00 C +ATOM 1529 CG1 ILE 162 3.702 -12.106 -0.087 1.00 0.00 C +ATOM 1530 CD1 ILE 162 5.030 -11.496 -0.662 1.00 0.00 C +ATOM 1531 C ILE 162 2.213 -10.717 3.238 1.00 0.00 C +ATOM 1532 O ILE 162 1.804 -11.728 3.823 1.00 0.00 O +ATOM 1533 N THR 163 1.695 -9.492 3.425 1.00 0.00 N +ATOM 1534 H THR 163 2.022 -8.734 2.893 1.00 0.00 H +ATOM 1535 CA THR 163 0.630 -9.173 4.400 1.00 0.00 C +ATOM 1536 CB THR 163 1.112 -8.024 5.370 1.00 0.00 C +ATOM 1537 OG1 THR 163 2.241 -8.479 6.123 1.00 0.00 O +ATOM 1538 HG1 THR 163 1.996 -9.220 6.683 1.00 0.00 H +ATOM 1539 CG2 THR 163 0.014 -7.555 6.323 1.00 0.00 C +ATOM 1540 C THR 163 -0.762 -8.809 3.838 1.00 0.00 C +ATOM 1541 O THR 163 -0.877 -8.118 2.820 1.00 0.00 O +ATOM 1542 N GLY 164 -1.800 -9.329 4.503 1.00 0.00 N +ATOM 1543 H GLY 164 -1.664 -9.947 5.254 1.00 0.00 H +ATOM 1544 CA GLY 164 -3.183 -9.024 4.163 1.00 0.00 C +ATOM 1545 C GLY 164 -3.907 -8.651 5.444 1.00 0.00 C +ATOM 1546 O GLY 164 -4.029 -9.505 6.317 1.00 0.00 O +ATOM 1547 N PHE 165 -4.512 -7.459 5.503 1.00 0.00 N +ATOM 1548 H PHE 165 -4.499 -6.881 4.712 1.00 0.00 H +ATOM 1549 CA PHE 165 -5.197 -6.988 6.719 1.00 0.00 C +ATOM 1550 CB PHE 165 -4.569 -5.647 7.189 1.00 0.00 C +ATOM 1551 CG PHE 165 -4.764 -5.321 8.679 1.00 0.00 C +ATOM 1552 CD1 PHE 165 -5.726 -4.371 9.088 1.00 0.00 C +ATOM 1553 CD2 PHE 165 -3.954 -5.918 9.669 1.00 0.00 C +ATOM 1554 CE1 PHE 165 -5.880 -4.017 10.453 1.00 0.00 C +ATOM 1555 CE2 PHE 165 -4.097 -5.575 11.034 1.00 0.00 C +ATOM 1556 CZ PHE 165 -5.062 -4.621 11.428 1.00 0.00 C +ATOM 1557 C PHE 165 -6.728 -6.869 6.611 1.00 0.00 C +ATOM 1558 O PHE 165 -7.286 -6.993 5.520 1.00 0.00 O +ATOM 1559 N THR 166 -7.369 -6.598 7.762 1.00 0.00 N +ATOM 1560 H THR 166 -6.820 -6.516 8.573 1.00 0.00 H +ATOM 1561 CA THR 166 -8.830 -6.432 7.952 1.00 0.00 C +ATOM 1562 CB THR 166 -9.160 -6.011 9.427 1.00 0.00 C +ATOM 1563 OG1 THR 166 -8.769 -4.650 9.649 1.00 0.00 O +ATOM 1564 HG1 THR 166 -8.975 -4.401 10.554 1.00 0.00 H +ATOM 1565 CG2 THR 166 -8.429 -6.896 10.426 1.00 0.00 C +ATOM 1566 C THR 166 -9.453 -5.428 6.954 1.00 0.00 C +ATOM 1567 O THR 166 -8.757 -4.511 6.496 1.00 0.00 O +ATOM 1568 N ASP 167 -10.737 -5.643 6.600 1.00 0.00 N +ATOM 1569 H ASP 167 -11.220 -6.392 7.013 1.00 0.00 H +ATOM 1570 CA ASP 167 -11.558 -4.860 5.624 1.00 0.00 C +ATOM 1571 CB ASP 167 -11.407 -3.320 5.785 1.00 0.00 C +ATOM 1572 CG ASP 167 -12.629 -2.541 5.291 1.00 0.00 C +ATOM 1573 OD1 ASP 167 -13.548 -2.291 6.102 1.00 0.00 O +ATOM 1574 OD2 ASP 167 -12.660 -2.168 4.098 1.00 0.00 O +ATOM 1575 C ASP 167 -11.194 -5.322 4.190 1.00 0.00 C +ATOM 1576 O ASP 167 -11.986 -5.165 3.252 1.00 0.00 O +ATOM 1577 N VAL 168 -9.991 -5.904 4.073 1.00 0.00 N +ATOM 1578 H VAL 168 -9.387 -6.003 4.829 1.00 0.00 H +ATOM 1579 CA VAL 168 -9.401 -6.466 2.842 1.00 0.00 C +ATOM 1580 CB VAL 168 -7.979 -5.833 2.538 1.00 0.00 C +ATOM 1581 CG1 VAL 168 -7.452 -6.271 1.163 1.00 0.00 C +ATOM 1582 CG2 VAL 168 -8.060 -4.309 2.580 1.00 0.00 C +ATOM 1583 C VAL 168 -9.288 -7.974 3.173 1.00 0.00 C +ATOM 1584 O VAL 168 -9.294 -8.823 2.275 1.00 0.00 O +ATOM 1585 N GLY 169 -9.191 -8.265 4.479 1.00 0.00 N +ATOM 1586 H GLY 169 -9.181 -7.548 5.150 1.00 0.00 H +ATOM 1587 CA GLY 169 -9.106 -9.620 5.021 1.00 0.00 C +ATOM 1588 C GLY 169 -10.417 -10.381 4.868 1.00 0.00 C +ATOM 1589 O GLY 169 -10.418 -11.594 4.627 1.00 0.00 O +ATOM 1590 N GLU 170 -11.526 -9.641 5.010 1.00 0.00 N +ATOM 1591 H GLU 170 -11.418 -8.683 5.200 1.00 0.00 H +ATOM 1592 CA GLU 170 -12.909 -10.151 4.901 1.00 0.00 C +ATOM 1593 CB GLU 170 -13.922 -9.062 5.286 1.00 0.00 C +ATOM 1594 CG GLU 170 -13.888 -8.632 6.748 1.00 0.00 C +ATOM 1595 CD GLU 170 -14.909 -7.556 7.066 1.00 0.00 C +ATOM 1596 OE1 GLU 170 -14.572 -6.359 6.948 1.00 0.00 O +ATOM 1597 OE2 GLU 170 -16.049 -7.907 7.438 1.00 0.00 O +ATOM 1598 C GLU 170 -13.231 -10.660 3.486 1.00 0.00 C +ATOM 1599 O GLU 170 -13.935 -11.667 3.336 1.00 0.00 O +ATOM 1600 N THR 171 -12.711 -9.956 2.468 1.00 0.00 N +ATOM 1601 H THR 171 -12.164 -9.163 2.673 1.00 0.00 H +ATOM 1602 CA THR 171 -12.895 -10.295 1.042 1.00 0.00 C +ATOM 1603 CB THR 171 -12.488 -9.121 0.099 1.00 0.00 C +ATOM 1604 OG1 THR 171 -11.172 -8.662 0.432 1.00 0.00 O +ATOM 1605 HG1 THR 171 -10.525 -9.356 0.284 1.00 0.00 H +ATOM 1606 CG2 THR 171 -13.477 -7.966 0.215 1.00 0.00 C +ATOM 1607 C THR 171 -12.156 -11.587 0.634 1.00 0.00 C +ATOM 1608 O THR 171 -12.747 -12.449 -0.026 1.00 0.00 O +ATOM 1609 N ILE 172 -10.889 -11.725 1.061 1.00 0.00 N +ATOM 1610 H ILE 172 -10.492 -11.004 1.599 1.00 0.00 H +ATOM 1611 CA ILE 172 -10.051 -12.910 0.767 1.00 0.00 C +ATOM 1612 CB ILE 172 -8.508 -12.651 1.004 1.00 0.00 C +ATOM 1613 CG2 ILE 172 -7.930 -11.915 -0.187 1.00 0.00 C +ATOM 1614 CG1 ILE 172 -8.233 -11.882 2.311 1.00 0.00 C +ATOM 1615 CD1 ILE 172 -7.262 -12.564 3.279 1.00 0.00 C +ATOM 1616 C ILE 172 -10.500 -14.206 1.478 1.00 0.00 C +ATOM 1617 O ILE 172 -10.605 -15.256 0.834 1.00 0.00 O +ATOM 1618 N LEU 173 -10.760 -14.111 2.791 1.00 0.00 N +ATOM 1619 H LEU 173 -10.647 -13.249 3.252 1.00 0.00 H +ATOM 1620 CA LEU 173 -11.219 -15.241 3.624 1.00 0.00 C +ATOM 1621 CB LEU 173 -11.029 -14.934 5.127 1.00 0.00 C +ATOM 1622 CG LEU 173 -9.646 -14.649 5.754 1.00 0.00 C +ATOM 1623 CD1 LEU 173 -9.851 -13.854 7.032 1.00 0.00 C +ATOM 1624 CD2 LEU 173 -8.819 -15.920 6.038 1.00 0.00 C +ATOM 1625 C LEU 173 -12.672 -15.645 3.330 1.00 0.00 C +ATOM 1626 O LEU 173 -12.959 -16.833 3.143 1.00 0.00 O +ATOM 1627 N GLY 174 -13.560 -14.639 3.263 1.00 0.00 N +ATOM 1628 H GLY 174 -13.271 -13.711 3.406 1.00 0.00 H +ATOM 1629 CA GLY 174 -14.988 -14.816 2.983 1.00 0.00 C +ATOM 1630 C GLY 174 -15.718 -15.918 3.739 1.00 0.00 C +ATOM 1631 O GLY 174 -16.114 -15.736 4.896 1.00 0.00 O +ATOM 1632 N VAL 175 -15.883 -17.057 3.054 1.00 0.00 N +ATOM 1633 H VAL 175 -15.554 -17.105 2.131 1.00 0.00 H +ATOM 1634 CA VAL 175 -16.532 -18.273 3.576 1.00 0.00 C +ATOM 1635 CB VAL 175 -17.753 -18.729 2.677 1.00 0.00 C +ATOM 1636 CG1 VAL 175 -18.623 -19.765 3.411 1.00 0.00 C +ATOM 1637 CG2 VAL 175 -18.612 -17.530 2.275 1.00 0.00 C +ATOM 1638 C VAL 175 -15.398 -19.328 3.569 1.00 0.00 C +ATOM 1639 O VAL 175 -14.645 -19.421 2.587 1.00 0.00 O +ATOM 1640 N ASP 176 -15.262 -20.077 4.672 1.00 0.00 N +ATOM 1641 H ASP 176 -15.888 -19.961 5.421 1.00 0.00 H +ATOM 1642 CA ASP 176 -14.208 -21.098 4.845 1.00 0.00 C +ATOM 1643 CB ASP 176 -14.027 -21.440 6.344 1.00 0.00 C +ATOM 1644 CG ASP 176 -15.345 -21.777 7.055 1.00 0.00 C +ATOM 1645 OD1 ASP 176 -15.988 -20.851 7.597 1.00 0.00 O +ATOM 1646 OD2 ASP 176 -15.724 -22.969 7.082 1.00 0.00 O +ATOM 1647 C ASP 176 -14.240 -22.392 3.998 1.00 0.00 C +ATOM 1648 O ASP 176 -13.215 -22.752 3.407 1.00 0.00 O +ATOM 1649 N SER 177 -15.396 -23.071 3.944 1.00 0.00 N +ATOM 1650 H SER 177 -16.184 -22.732 4.423 1.00 0.00 H +ATOM 1651 CA SER 177 -15.558 -24.327 3.181 1.00 0.00 C +ATOM 1652 CB SER 177 -16.789 -25.092 3.682 1.00 0.00 C +ATOM 1653 OG SER 177 -16.663 -25.417 5.056 1.00 0.00 O +ATOM 1654 HG SER 177 -17.445 -25.894 5.345 1.00 0.00 H +ATOM 1655 C SER 177 -15.595 -24.222 1.641 1.00 0.00 C +ATOM 1656 O SER 177 -14.843 -24.929 0.960 1.00 0.00 O +ATOM 1657 N ILE 178 -16.466 -23.346 1.113 1.00 0.00 N +ATOM 1658 H ILE 178 -17.029 -22.813 1.717 1.00 0.00 H +ATOM 1659 CA ILE 178 -16.635 -23.110 -0.338 1.00 0.00 C +ATOM 1660 CB ILE 178 -18.110 -22.591 -0.663 1.00 0.00 C +ATOM 1661 CG2 ILE 178 -18.326 -21.141 -0.168 1.00 0.00 C +ATOM 1662 CG1 ILE 178 -18.456 -22.779 -2.155 1.00 0.00 C +ATOM 1663 CD1 ILE 178 -19.868 -23.307 -2.425 1.00 0.00 C +ATOM 1664 C ILE 178 -15.509 -22.285 -1.027 1.00 0.00 C +ATOM 1665 O ILE 178 -15.008 -22.687 -2.084 1.00 0.00 O +ATOM 1666 N LEU 179 -15.125 -21.161 -0.391 1.00 0.00 N +ATOM 1667 H LEU 179 -15.544 -20.932 0.467 1.00 0.00 H +ATOM 1668 CA LEU 179 -14.099 -20.180 -0.845 1.00 0.00 C +ATOM 1669 CB LEU 179 -12.689 -20.465 -0.235 1.00 0.00 C +ATOM 1670 CG LEU 179 -11.911 -21.803 -0.254 1.00 0.00 C +ATOM 1671 CD1 LEU 179 -11.062 -21.967 -1.526 1.00 0.00 C +ATOM 1672 CD2 LEU 179 -11.004 -21.849 0.965 1.00 0.00 C +ATOM 1673 C LEU 179 -14.032 -19.848 -2.361 1.00 0.00 C +ATOM 1674 O LEU 179 -13.452 -20.609 -3.150 1.00 0.00 O +ATOM 1675 N LYS 180 -14.680 -18.737 -2.741 1.00 0.00 N +ATOM 1676 H LYS 180 -15.155 -18.189 -2.079 1.00 0.00 H +ATOM 1677 CA LYS 180 -14.745 -18.243 -4.131 1.00 0.00 C +ATOM 1678 CB LYS 180 -16.199 -17.947 -4.536 1.00 0.00 C +ATOM 1679 CG LYS 180 -17.086 -19.175 -4.705 1.00 0.00 C +ATOM 1680 CD LYS 180 -18.468 -18.781 -5.219 1.00 0.00 C +ATOM 1681 CE LYS 180 -19.385 -19.987 -5.401 1.00 0.00 C +ATOM 1682 NZ LYS 180 -19.826 -20.593 -4.111 1.00 0.00 N +ATOM 1683 HZ1 LYS 180 -18.994 -20.911 -3.575 1.00 0.00 H +ATOM 1684 HZ2 LYS 180 -20.347 -19.885 -3.555 1.00 0.00 H +ATOM 1685 HZ3 LYS 180 -20.445 -21.406 -4.304 1.00 0.00 H +ATOM 1686 C LYS 180 -13.891 -16.977 -4.310 1.00 0.00 C +ATOM 1687 O LYS 180 -13.550 -16.320 -3.319 1.00 0.00 O +ATOM 1688 N ALA 181 -13.558 -16.651 -5.567 1.00 0.00 N +ATOM 1689 H ALA 181 -13.855 -17.208 -6.320 1.00 0.00 H +ATOM 1690 CA ALA 181 -12.748 -15.474 -5.923 1.00 0.00 C +ATOM 1691 CB ALA 181 -11.643 -15.869 -6.907 1.00 0.00 C +ATOM 1692 C ALA 181 -13.595 -14.322 -6.493 1.00 0.00 C +ATOM 1693 O ALA 181 -13.595 -13.225 -5.922 1.00 0.00 O +ATOM 1694 N LYS 182 -14.315 -14.597 -7.597 1.00 0.00 N +ATOM 1695 H LYS 182 -14.271 -15.500 -7.982 1.00 0.00 H +ATOM 1696 CA LYS 182 -15.209 -13.668 -8.343 1.00 0.00 C +ATOM 1697 CB LYS 182 -16.686 -14.138 -8.266 1.00 0.00 C +ATOM 1698 CG LYS 182 -17.253 -14.419 -6.859 1.00 0.00 C +ATOM 1699 CD LYS 182 -18.712 -14.841 -6.926 1.00 0.00 C +ATOM 1700 CE LYS 182 -19.279 -15.089 -5.538 1.00 0.00 C +ATOM 1701 NZ LYS 182 -20.708 -15.505 -5.588 1.00 0.00 N +ATOM 1702 HZ1 LYS 182 -21.271 -14.757 -6.041 1.00 0.00 H +ATOM 1703 HZ2 LYS 182 -21.057 -15.664 -4.621 1.00 0.00 H +ATOM 1704 HZ3 LYS 182 -20.794 -16.384 -6.137 1.00 0.00 H +ATOM 1705 C LYS 182 -15.097 -12.131 -8.143 1.00 0.00 C +ATOM 1706 O LYS 182 -14.632 -11.425 -9.046 1.00 0.00 O +ATOM 1707 N ASN 183 -15.524 -11.645 -6.967 1.00 0.00 N +ATOM 1708 H ASN 183 -15.886 -12.254 -6.286 1.00 0.00 H +ATOM 1709 CA ASN 183 -15.496 -10.218 -6.595 1.00 0.00 C +ATOM 1710 CB ASN 183 -16.933 -9.668 -6.456 1.00 0.00 C +ATOM 1711 CG ASN 183 -17.029 -8.165 -6.726 1.00 0.00 C +ATOM 1712 OD1 ASN 183 -16.907 -7.348 -5.811 1.00 0.00 O +ATOM 1713 ND2 ASN 183 -17.265 -7.801 -7.983 1.00 0.00 N +ATOM 1714 HD21 ASN 183 -17.330 -6.842 -8.174 1.00 0.00 H +ATOM 1715 HD22 ASN 183 -17.365 -8.493 -8.671 1.00 0.00 H +ATOM 1716 C ASN 183 -14.741 -10.067 -5.261 1.00 0.00 C +ATOM 1717 O ASN 183 -14.117 -9.026 -5.016 1.00 0.00 O +ATOM 1718 N LEU 184 -14.803 -11.113 -4.424 1.00 0.00 N +ATOM 1719 H LEU 184 -15.301 -11.921 -4.676 1.00 0.00 H +ATOM 1720 CA LEU 184 -14.155 -11.154 -3.099 1.00 0.00 C +ATOM 1721 CB LEU 184 -15.117 -11.769 -2.049 1.00 0.00 C +ATOM 1722 CG LEU 184 -16.407 -11.043 -1.620 1.00 0.00 C +ATOM 1723 CD1 LEU 184 -17.651 -11.730 -2.201 1.00 0.00 C +ATOM 1724 CD2 LEU 184 -16.494 -11.024 -0.099 1.00 0.00 C +ATOM 1725 C LEU 184 -12.790 -11.888 -3.117 1.00 0.00 C +ATOM 1726 O LEU 184 -12.671 -13.025 -2.633 1.00 0.00 O +ATOM 1727 N ALA 185 -11.787 -11.240 -3.732 1.00 0.00 N +ATOM 1728 H ALA 185 -11.945 -10.360 -4.141 1.00 0.00 H +ATOM 1729 CA ALA 185 -10.404 -11.750 -3.856 1.00 0.00 C +ATOM 1730 CB ALA 185 -10.276 -12.726 -5.049 1.00 0.00 C +ATOM 1731 C ALA 185 -9.405 -10.593 -4.018 1.00 0.00 C +ATOM 1732 O ALA 185 -9.536 -9.783 -4.947 1.00 0.00 O +ATOM 1733 N THR 186 -8.439 -10.502 -3.087 1.00 0.00 N +ATOM 1734 H THR 186 -8.405 -11.160 -2.370 1.00 0.00 H +ATOM 1735 CA THR 186 -7.382 -9.466 -3.078 1.00 0.00 C +ATOM 1736 CB THR 186 -7.698 -8.286 -2.083 1.00 0.00 C +ATOM 1737 OG1 THR 186 -8.097 -8.819 -0.814 1.00 0.00 O +ATOM 1738 HG1 THR 186 -8.361 -8.106 -0.232 1.00 0.00 H +ATOM 1739 CG2 THR 186 -8.798 -7.386 -2.632 1.00 0.00 C +ATOM 1740 C THR 186 -5.964 -10.037 -2.817 1.00 0.00 C +ATOM 1741 O THR 186 -5.282 -10.408 -3.775 1.00 0.00 O +ATOM 1742 N VAL 187 -5.540 -10.119 -1.543 1.00 0.00 N +ATOM 1743 H VAL 187 -6.149 -9.873 -0.813 1.00 0.00 H +ATOM 1744 CA VAL 187 -4.208 -10.612 -1.114 1.00 0.00 C +ATOM 1745 CB VAL 187 -3.844 -10.136 0.353 1.00 0.00 C +ATOM 1746 CG1 VAL 187 -3.537 -8.651 0.376 1.00 0.00 C +ATOM 1747 CG2 VAL 187 -4.981 -10.441 1.343 1.00 0.00 C +ATOM 1748 C VAL 187 -3.881 -12.120 -1.264 1.00 0.00 C +ATOM 1749 O VAL 187 -2.809 -12.462 -1.778 1.00 0.00 O +ATOM 1750 N GLU 188 -4.812 -12.994 -0.845 1.00 0.00 N +ATOM 1751 H GLU 188 -5.651 -12.656 -0.476 1.00 0.00 H +ATOM 1752 CA GLU 188 -4.652 -14.465 -0.888 1.00 0.00 C +ATOM 1753 CB GLU 188 -5.802 -15.170 -0.160 1.00 0.00 C +ATOM 1754 CG GLU 188 -5.627 -15.248 1.349 1.00 0.00 C +ATOM 1755 CD GLU 188 -6.677 -16.118 2.018 1.00 0.00 C +ATOM 1756 OE1 GLU 188 -6.436 -17.335 2.166 1.00 0.00 O +ATOM 1757 OE2 GLU 188 -7.742 -15.588 2.400 1.00 0.00 O +ATOM 1758 C GLU 188 -4.451 -15.102 -2.269 1.00 0.00 C +ATOM 1759 O GLU 188 -3.625 -16.010 -2.405 1.00 0.00 O +ATOM 1760 N ASP 189 -5.176 -14.609 -3.283 1.00 0.00 N +ATOM 1761 H ASP 189 -5.806 -13.872 -3.121 1.00 0.00 H +ATOM 1762 CA ASP 189 -5.086 -15.111 -4.670 1.00 0.00 C +ATOM 1763 CB ASP 189 -6.260 -14.585 -5.530 1.00 0.00 C +ATOM 1764 CG ASP 189 -6.468 -13.069 -5.417 1.00 0.00 C +ATOM 1765 OD1 ASP 189 -7.137 -12.623 -4.459 1.00 0.00 O +ATOM 1766 OD2 ASP 189 -5.969 -12.333 -6.294 1.00 0.00 O +ATOM 1767 C ASP 189 -3.722 -14.802 -5.322 1.00 0.00 C +ATOM 1768 O ASP 189 -3.104 -15.692 -5.923 1.00 0.00 O +ATOM 1769 N VAL 190 -3.257 -13.553 -5.152 1.00 0.00 N +ATOM 1770 H VAL 190 -3.795 -12.908 -4.640 1.00 0.00 H +ATOM 1771 CA VAL 190 -1.963 -13.071 -5.685 1.00 0.00 C +ATOM 1772 CB VAL 190 -1.840 -11.496 -5.647 1.00 0.00 C +ATOM 1773 CG1 VAL 190 -0.815 -11.012 -6.678 1.00 0.00 C +ATOM 1774 CG2 VAL 190 -3.180 -10.836 -5.950 1.00 0.00 C +ATOM 1775 C VAL 190 -0.789 -13.742 -4.927 1.00 0.00 C +ATOM 1776 O VAL 190 0.230 -14.083 -5.542 1.00 0.00 O +ATOM 1777 N ALA 191 -0.960 -13.932 -3.608 1.00 0.00 N +ATOM 1778 H ALA 191 -1.791 -13.637 -3.174 1.00 0.00 H +ATOM 1779 CA ALA 191 0.034 -14.571 -2.720 1.00 0.00 C +ATOM 1780 CB ALA 191 -0.309 -14.311 -1.259 1.00 0.00 C +ATOM 1781 C ALA 191 0.206 -16.081 -2.974 1.00 0.00 C +ATOM 1782 O ALA 191 1.327 -16.593 -2.923 1.00 0.00 O +ATOM 1783 N LYS 192 -0.912 -16.784 -3.207 1.00 0.00 N +ATOM 1784 H LYS 192 -1.784 -16.331 -3.195 1.00 0.00 H +ATOM 1785 CA LYS 192 -0.928 -18.235 -3.494 1.00 0.00 C +ATOM 1786 CB LYS 192 -2.343 -18.809 -3.355 1.00 0.00 C +ATOM 1787 CG LYS 192 -2.806 -19.037 -1.924 1.00 0.00 C +ATOM 1788 CD LYS 192 -4.192 -19.675 -1.899 1.00 0.00 C +ATOM 1789 CE LYS 192 -4.710 -19.882 -0.480 1.00 0.00 C +ATOM 1790 NZ LYS 192 -5.060 -18.606 0.212 1.00 0.00 N +ATOM 1791 HZ1 LYS 192 -5.803 -18.114 -0.324 1.00 0.00 H +ATOM 1792 HZ2 LYS 192 -4.217 -18.001 0.271 1.00 0.00 H +ATOM 1793 HZ3 LYS 192 -5.405 -18.815 1.170 1.00 0.00 H +ATOM 1794 C LYS 192 -0.344 -18.609 -4.870 1.00 0.00 C +ATOM 1795 O LYS 192 0.369 -19.612 -4.986 1.00 0.00 O +ATOM 1796 N LYS 193 -0.657 -17.800 -5.894 1.00 0.00 N +ATOM 1797 H LYS 193 -1.239 -17.017 -5.735 1.00 0.00 H +ATOM 1798 CA LYS 193 -0.201 -17.996 -7.288 1.00 0.00 C +ATOM 1799 CB LYS 193 -1.042 -17.149 -8.255 1.00 0.00 C +ATOM 1800 CG LYS 193 -2.476 -17.633 -8.443 1.00 0.00 C +ATOM 1801 CD LYS 193 -3.240 -16.739 -9.414 1.00 0.00 C +ATOM 1802 CE LYS 193 -4.680 -17.205 -9.617 1.00 0.00 C +ATOM 1803 NZ LYS 193 -5.540 -17.031 -8.408 1.00 0.00 N +ATOM 1804 HZ1 LYS 193 -5.144 -17.580 -7.619 1.00 0.00 H +ATOM 1805 HZ2 LYS 193 -6.502 -17.367 -8.616 1.00 0.00 H +ATOM 1806 HZ3 LYS 193 -5.573 -16.024 -8.149 1.00 0.00 H +ATOM 1807 C LYS 193 1.299 -17.779 -7.581 1.00 0.00 C +ATOM 1808 O LYS 193 1.914 -18.613 -8.257 1.00 0.00 O +ATOM 1809 N TYR 194 1.870 -16.673 -7.076 1.00 0.00 N +ATOM 1810 H TYR 194 1.338 -16.047 -6.537 1.00 0.00 H +ATOM 1811 CA TYR 194 3.291 -16.313 -7.276 1.00 0.00 C +ATOM 1812 CB TYR 194 3.437 -15.197 -8.347 1.00 0.00 C +ATOM 1813 CG TYR 194 2.972 -15.541 -9.768 1.00 0.00 C +ATOM 1814 CD1 TYR 194 3.869 -16.089 -10.719 1.00 0.00 C +ATOM 1815 CE1 TYR 194 3.451 -16.376 -12.048 1.00 0.00 C +ATOM 1816 CD2 TYR 194 1.641 -15.287 -10.185 1.00 0.00 C +ATOM 1817 CE2 TYR 194 1.216 -15.571 -11.512 1.00 0.00 C +ATOM 1818 CZ TYR 194 2.127 -16.114 -12.433 1.00 0.00 C +ATOM 1819 OH TYR 194 1.721 -16.392 -13.718 1.00 0.00 O +ATOM 1820 HH TYR 194 0.796 -16.162 -13.834 1.00 0.00 H +ATOM 1821 C TYR 194 3.976 -15.844 -5.991 1.00 0.00 C +ATOM 1822 O TYR 194 5.189 -16.031 -5.828 1.00 0.00 O +ATOM 1823 N GLY 195 3.191 -15.259 -5.079 1.00 0.00 N +ATOM 1824 H GLY 195 2.225 -15.162 -5.230 1.00 0.00 H +ATOM 1825 CA GLY 195 3.703 -14.733 -3.814 1.00 0.00 C +ATOM 1826 C GLY 195 4.193 -15.720 -2.761 1.00 0.00 C +ATOM 1827 O GLY 195 4.565 -16.853 -3.090 1.00 0.00 O +ATOM 1828 N ALA 196 4.181 -15.270 -1.501 1.00 0.00 N +ATOM 1829 H ALA 196 3.847 -14.364 -1.324 1.00 0.00 H +ATOM 1830 CA ALA 196 4.639 -16.044 -0.340 1.00 0.00 C +ATOM 1831 CB ALA 196 5.674 -15.229 0.435 1.00 0.00 C +ATOM 1832 C ALA 196 3.510 -16.505 0.600 1.00 0.00 C +ATOM 1833 O ALA 196 2.338 -16.526 0.205 1.00 0.00 O +ATOM 1834 N LYS 197 3.890 -16.867 1.836 1.00 0.00 N +ATOM 1835 H LYS 197 4.840 -16.832 2.086 1.00 0.00 H +ATOM 1836 CA LYS 197 2.997 -17.341 2.912 1.00 0.00 C +ATOM 1837 CB LYS 197 3.781 -18.212 3.903 1.00 0.00 C +ATOM 1838 CG LYS 197 4.228 -19.563 3.353 1.00 0.00 C +ATOM 1839 CD LYS 197 4.997 -20.361 4.400 1.00 0.00 C +ATOM 1840 CE LYS 197 5.454 -21.719 3.871 1.00 0.00 C +ATOM 1841 NZ LYS 197 4.331 -22.673 3.624 1.00 0.00 N +ATOM 1842 HZ1 LYS 197 4.713 -23.572 3.266 1.00 0.00 H +ATOM 1843 HZ2 LYS 197 3.819 -22.843 4.513 1.00 0.00 H +ATOM 1844 HZ3 LYS 197 3.680 -22.268 2.921 1.00 0.00 H +ATOM 1845 C LYS 197 2.322 -16.187 3.674 1.00 0.00 C +ATOM 1846 O LYS 197 2.940 -15.132 3.871 1.00 0.00 O +ATOM 1847 N TYR 198 1.061 -16.395 4.075 1.00 0.00 N +ATOM 1848 H TYR 198 0.608 -17.246 3.883 1.00 0.00 H +ATOM 1849 CA TYR 198 0.270 -15.397 4.816 1.00 0.00 C +ATOM 1850 CB TYR 198 -1.084 -15.101 4.096 1.00 0.00 C +ATOM 1851 CG TYR 198 -1.976 -16.304 3.740 1.00 0.00 C +ATOM 1852 CD1 TYR 198 -1.836 -16.981 2.503 1.00 0.00 C +ATOM 1853 CE1 TYR 198 -2.675 -18.079 2.164 1.00 0.00 C +ATOM 1854 CD2 TYR 198 -2.982 -16.755 4.631 1.00 0.00 C +ATOM 1855 CE2 TYR 198 -3.825 -17.851 4.299 1.00 0.00 C +ATOM 1856 CZ TYR 198 -3.663 -18.504 3.066 1.00 0.00 C +ATOM 1857 OH TYR 198 -4.475 -19.566 2.741 1.00 0.00 O +ATOM 1858 HH TYR 198 -5.097 -19.741 3.452 1.00 0.00 H +ATOM 1859 C TYR 198 0.042 -15.776 6.294 1.00 0.00 C +ATOM 1860 O TYR 198 -0.261 -16.935 6.604 1.00 0.00 O +ATOM 1861 N LEU 199 0.192 -14.784 7.181 1.00 0.00 N +ATOM 1862 H LEU 199 0.454 -13.887 6.886 1.00 0.00 H +ATOM 1863 CA LEU 199 0.026 -14.928 8.638 1.00 0.00 C +ATOM 1864 CB LEU 199 1.279 -14.359 9.367 1.00 0.00 C +ATOM 1865 CG LEU 199 2.659 -15.044 9.604 1.00 0.00 C +ATOM 1866 CD1 LEU 199 2.582 -16.174 10.646 1.00 0.00 C +ATOM 1867 CD2 LEU 199 3.355 -15.522 8.315 1.00 0.00 C +ATOM 1868 C LEU 199 -1.258 -14.223 9.120 1.00 0.00 C +ATOM 1869 O LEU 199 -1.209 -13.328 9.975 1.00 0.00 O +ATOM 1870 N ALA 200 -2.401 -14.640 8.559 1.00 0.00 N +ATOM 1871 H ALA 200 -2.400 -15.361 7.892 1.00 0.00 H +ATOM 1872 CA ALA 200 -3.715 -14.069 8.888 1.00 0.00 C +ATOM 1873 CB ALA 200 -4.537 -13.855 7.615 1.00 0.00 C +ATOM 1874 C ALA 200 -4.522 -14.847 9.959 1.00 0.00 C +ATOM 1875 O ALA 200 -4.946 -15.984 9.710 1.00 0.00 O +ATOM 1876 N PRO 201 -4.707 -14.252 11.180 1.00 0.00 N +ATOM 1877 CD PRO 201 -4.002 -13.024 11.619 1.00 0.00 C +ATOM 1878 CA PRO 201 -5.440 -14.812 12.335 1.00 0.00 C +ATOM 1879 CB PRO 201 -5.294 -13.706 13.381 1.00 0.00 C +ATOM 1880 CG PRO 201 -3.950 -13.188 13.116 1.00 0.00 C +ATOM 1881 C PRO 201 -6.926 -15.197 12.140 1.00 0.00 C +ATOM 1882 O PRO 201 -7.529 -15.790 13.045 1.00 0.00 O +ATOM 1883 N VAL 202 -7.481 -14.907 10.947 1.00 0.00 N +ATOM 1884 H VAL 202 -6.929 -14.476 10.259 1.00 0.00 H +ATOM 1885 CA VAL 202 -8.891 -15.167 10.521 1.00 0.00 C +ATOM 1886 CB VAL 202 -9.108 -16.666 9.952 1.00 0.00 C +ATOM 1887 CG1 VAL 202 -9.003 -17.738 11.053 1.00 0.00 C +ATOM 1888 CG2 VAL 202 -10.426 -16.794 9.168 1.00 0.00 C +ATOM 1889 C VAL 202 -10.018 -14.710 11.493 1.00 0.00 C +ATOM 1890 O VAL 202 -9.963 -14.989 12.697 1.00 0.00 O +ATOM 1891 N GLY 203 -11.023 -14.023 10.941 1.00 0.00 N +ATOM 1892 H GLY 203 -11.039 -13.831 9.977 1.00 0.00 H +ATOM 1893 CA GLY 203 -12.144 -13.525 11.728 1.00 0.00 C +ATOM 1894 C GLY 203 -12.823 -12.271 11.169 1.00 0.00 C +ATOM 1895 O GLY 203 -14.060 -12.265 11.156 1.00 0.00 O +ATOM 1896 N PRO 204 -12.099 -11.197 10.717 1.00 0.00 N +ATOM 1897 CD PRO 204 -12.860 -10.134 10.021 1.00 0.00 C +ATOM 1898 CA PRO 204 -10.648 -10.919 10.627 1.00 0.00 C +ATOM 1899 CB PRO 204 -10.584 -9.704 9.679 1.00 0.00 C +ATOM 1900 CG PRO 204 -11.876 -8.989 9.946 1.00 0.00 C +ATOM 1901 C PRO 204 -9.860 -10.749 11.965 1.00 0.00 C +ATOM 1902 O PRO 204 -10.299 -11.253 13.005 1.00 0.00 O +ATOM 1903 N TRP 205 -8.731 -10.032 11.913 1.00 0.00 N +ATOM 1904 H TRP 205 -8.475 -9.583 11.081 1.00 0.00 H +ATOM 1905 CA TRP 205 -7.809 -9.811 13.045 1.00 0.00 C +ATOM 1906 CB TRP 205 -6.397 -10.290 12.622 1.00 0.00 C +ATOM 1907 CG TRP 205 -5.982 -9.966 11.161 1.00 0.00 C +ATOM 1908 CD2 TRP 205 -6.589 -10.454 9.910 1.00 0.00 C +ATOM 1909 CE2 TRP 205 -5.746 -10.055 8.835 1.00 0.00 C +ATOM 1910 CE3 TRP 205 -7.051 -11.757 9.297 1.00 0.00 C +ATOM 1911 CD1 TRP 205 -4.931 -9.112 10.724 1.00 0.00 C +ATOM 1912 NE1 TRP 205 -4.843 -9.124 9.302 1.00 0.00 N +ATOM 1913 HE1 TRP 205 -4.246 -8.567 8.761 1.00 0.00 H +ATOM 1914 CZ2 TRP 205 -6.745 -10.227 7.749 1.00 0.00 C +ATOM 1915 CZ3 TRP 205 -6.259 -11.366 9.332 1.00 0.00 C +ATOM 1916 CH2 TRP 205 -6.998 -10.166 9.008 1.00 0.00 C +ATOM 1917 C TRP 205 -7.746 -8.380 13.624 1.00 0.00 C +ATOM 1918 O TRP 205 -8.667 -7.582 13.416 1.00 0.00 O +ATOM 1919 N ASP 206 -6.682 -8.106 14.398 1.00 0.00 N +ATOM 1920 H ASP 206 -6.012 -8.795 14.598 1.00 0.00 H +ATOM 1921 CA ASP 206 -6.406 -6.806 15.036 1.00 0.00 C +ATOM 1922 CB ASP 206 -6.532 -6.893 16.580 1.00 0.00 C +ATOM 1923 CG ASP 206 -5.822 -8.113 17.185 1.00 0.00 C +ATOM 1924 OD1 ASP 206 -4.627 -7.998 17.536 1.00 0.00 O +ATOM 1925 OD2 ASP 206 -6.467 -9.176 17.319 1.00 0.00 O +ATOM 1926 C ASP 206 -5.018 -6.271 14.627 1.00 0.00 C +ATOM 1927 O ASP 206 -4.845 -5.056 14.480 1.00 0.00 O +ATOM 1928 N ASP 207 -4.045 -7.186 14.480 1.00 0.00 N +ATOM 1929 H ASP 207 -4.236 -8.137 14.634 1.00 0.00 H +ATOM 1930 CA ASP 207 -2.651 -6.874 14.089 1.00 0.00 C +ATOM 1931 CB ASP 207 -1.734 -6.813 15.324 1.00 0.00 C +ATOM 1932 CG ASP 207 -0.567 -5.835 15.159 1.00 0.00 C +ATOM 1933 OD1 ASP 207 -0.725 -4.648 15.520 1.00 0.00 O +ATOM 1934 OD2 ASP 207 0.509 -6.259 14.684 1.00 0.00 O +ATOM 1935 C ASP 207 -2.114 -7.941 13.119 1.00 0.00 C +ATOM 1936 O ASP 207 -2.550 -9.098 13.170 1.00 0.00 O +ATOM 1937 N TYR 208 -1.179 -7.534 12.245 1.00 0.00 N +ATOM 1938 H TYR 208 -0.882 -6.597 12.238 1.00 0.00 H +ATOM 1939 CA TYR 208 -0.530 -8.412 11.249 1.00 0.00 C +ATOM 1940 CB TYR 208 -1.374 -8.487 9.934 1.00 0.00 C +ATOM 1941 CG TYR 208 -1.124 -9.665 8.967 1.00 0.00 C +ATOM 1942 CD1 TYR 208 0.184 -10.095 8.607 1.00 0.00 C +ATOM 1943 CE1 TYR 208 0.392 -11.070 7.609 1.00 0.00 C +ATOM 1944 CD2 TYR 208 -2.202 -10.266 8.305 1.00 0.00 C +ATOM 1945 CE2 TYR 208 -2.000 -11.245 7.300 1.00 0.00 C +ATOM 1946 CZ TYR 208 -0.706 -11.632 6.958 1.00 0.00 C +ATOM 1947 OH TYR 208 -0.522 -12.539 5.949 1.00 0.00 O +ATOM 1948 HH TYR 208 0.414 -12.714 5.822 1.00 0.00 H +ATOM 1949 C TYR 208 0.932 -7.957 10.969 1.00 0.00 C +ATOM 1950 O TYR 208 1.764 -7.947 11.883 1.00 0.00 O +ATOM 1951 N SER 209 1.209 -7.580 9.704 1.00 0.00 N +ATOM 1952 H SER 209 0.519 -7.544 9.013 1.00 0.00 H +ATOM 1953 CA SER 209 2.507 -7.149 9.123 1.00 0.00 C +ATOM 1954 CB SER 209 2.893 -5.727 9.583 1.00 0.00 C +ATOM 1955 OG SER 209 3.998 -5.219 8.853 1.00 0.00 O +ATOM 1956 HG SER 209 4.210 -4.336 9.165 1.00 0.00 H +ATOM 1957 C SER 209 3.665 -8.153 9.331 1.00 0.00 C +ATOM 1958 O SER 209 3.992 -8.508 10.471 1.00 0.00 O +ATOM 1959 N ILE 210 4.253 -8.612 8.212 1.00 0.00 N +ATOM 1960 H ILE 210 3.944 -8.306 7.332 1.00 0.00 H +ATOM 1961 CA ILE 210 5.373 -9.581 8.187 1.00 0.00 C +ATOM 1962 CB ILE 210 4.902 -11.073 7.887 1.00 0.00 C +ATOM 1963 CG2 ILE 210 4.399 -11.696 9.200 1.00 0.00 C +ATOM 1964 CG1 ILE 210 3.875 -11.142 6.731 1.00 0.00 C +ATOM 1965 CD1 ILE 210 3.541 -12.552 6.203 1.00 0.00 C +ATOM 1966 C ILE 210 6.568 -9.197 7.290 1.00 0.00 C +ATOM 1967 O ILE 210 6.370 -8.677 6.185 1.00 0.00 O +ATOM 1968 N THR 211 7.789 -9.427 7.795 1.00 0.00 N +ATOM 1969 H THR 211 7.887 -9.804 8.697 1.00 0.00 H +ATOM 1970 CA THR 211 9.057 -9.152 7.084 1.00 0.00 C +ATOM 1971 CB THR 211 9.814 -7.879 7.660 1.00 0.00 C +ATOM 1972 OG1 THR 211 11.094 -7.738 7.028 1.00 0.00 O +ATOM 1973 HG1 THR 211 11.644 -8.502 7.218 1.00 0.00 H +ATOM 1974 CG2 THR 211 9.986 -7.937 9.195 1.00 0.00 C +ATOM 1975 C THR 211 9.949 -10.418 7.096 1.00 0.00 C +ATOM 1976 O THR 211 10.107 -11.050 8.150 1.00 0.00 O +ATOM 1977 N ASP 212 10.477 -10.797 5.921 1.00 0.00 N +ATOM 1978 H ASP 212 10.298 -10.278 5.106 1.00 0.00 H +ATOM 1979 CA ASP 212 11.341 -11.984 5.762 1.00 0.00 C +ATOM 1980 CB ASP 212 10.580 -13.113 5.024 1.00 0.00 C +ATOM 1981 CG ASP 212 11.027 -14.515 5.446 1.00 0.00 C +ATOM 1982 OD1 ASP 212 10.436 -15.072 6.397 1.00 0.00 O +ATOM 1983 OD2 ASP 212 11.957 -15.063 4.815 1.00 0.00 O +ATOM 1984 C ASP 212 12.668 -11.667 5.043 1.00 0.00 C +ATOM 1985 O ASP 212 13.742 -11.949 5.587 1.00 0.00 O +ATOM 1986 N GLY 213 12.584 -11.087 3.839 1.00 0.00 N +ATOM 1987 H GLY 213 11.712 -10.864 3.446 1.00 0.00 H +ATOM 1988 CA GLY 213 13.769 -10.757 3.051 1.00 0.00 C +ATOM 1989 C GLY 213 14.095 -9.273 2.959 1.00 0.00 C +ATOM 1990 O GLY 213 14.111 -8.581 3.984 1.00 0.00 O +ATOM 1991 N ARG 214 14.352 -8.799 1.731 1.00 0.00 N +ATOM 1992 H ARG 214 14.318 -9.419 0.972 1.00 0.00 H +ATOM 1993 CA ARG 214 14.687 -7.392 1.433 1.00 0.00 C +ATOM 1994 CB ARG 214 15.511 -7.286 0.141 1.00 0.00 C +ATOM 1995 CG ARG 214 16.927 -7.861 0.234 1.00 0.00 C +ATOM 1996 CD ARG 214 17.696 -7.721 -1.079 1.00 0.00 C +ATOM 1997 NE ARG 214 18.043 -6.331 -1.392 1.00 0.00 N +ATOM 1998 HE ARG 214 17.766 -5.638 -0.757 1.00 0.00 H +ATOM 1999 CZ ARG 214 18.708 -5.930 -2.476 1.00 0.00 C +ATOM 2000 NH1 ARG 214 18.962 -4.640 -2.647 1.00 0.00 N +ATOM 2001 HH11 ARG 214 18.655 -3.975 -1.966 1.00 0.00 H +ATOM 2002 HH12 ARG 214 19.460 -4.331 -3.457 1.00 0.00 H +ATOM 2003 NH2 ARG 214 19.123 -6.801 -3.391 1.00 0.00 N +ATOM 2004 HH21 ARG 214 18.938 -7.777 -3.273 1.00 0.00 H +ATOM 2005 HH22 ARG 214 19.621 -6.481 -4.197 1.00 0.00 H +ATOM 2006 C ARG 214 13.427 -6.521 1.310 1.00 0.00 C +ATOM 2007 O ARG 214 13.465 -5.323 1.617 1.00 0.00 O +ATOM 2008 N LEU 215 12.320 -7.147 0.889 1.00 0.00 N +ATOM 2009 H LEU 215 12.338 -8.105 0.672 1.00 0.00 H +ATOM 2010 CA LEU 215 11.015 -6.482 0.716 1.00 0.00 C +ATOM 2011 CB LEU 215 10.312 -6.967 -0.575 1.00 0.00 C +ATOM 2012 CG LEU 215 10.983 -6.677 -1.935 1.00 0.00 C +ATOM 2013 CD1 LEU 215 11.536 -7.959 -2.572 1.00 0.00 C +ATOM 2014 CD2 LEU 215 9.992 -6.018 -2.877 1.00 0.00 C +ATOM 2015 C LEU 215 10.126 -6.718 1.947 1.00 0.00 C +ATOM 2016 O LEU 215 9.950 -7.865 2.385 1.00 0.00 O +ATOM 2017 N VAL 216 9.609 -5.617 2.510 1.00 0.00 N +ATOM 2018 H VAL 216 9.796 -4.730 2.133 1.00 0.00 H +ATOM 2019 CA VAL 216 8.742 -5.621 3.704 1.00 0.00 C +ATOM 2020 CB VAL 216 9.263 -4.618 4.814 1.00 0.00 C +ATOM 2021 CG1 VAL 216 8.441 -4.723 6.111 1.00 0.00 C +ATOM 2022 CG2 VAL 216 10.738 -4.877 5.120 1.00 0.00 C +ATOM 2023 C VAL 216 7.312 -5.243 3.280 1.00 0.00 C +ATOM 2024 O VAL 216 7.121 -4.436 2.362 1.00 0.00 O +ATOM 2025 N THR 217 6.330 -5.890 3.920 1.00 0.00 N +ATOM 2026 H THR 217 6.537 -6.568 4.601 1.00 0.00 H +ATOM 2027 CA THR 217 4.899 -5.661 3.676 1.00 0.00 C +ATOM 2028 CB THR 217 4.178 -6.955 3.202 1.00 0.00 C +ATOM 2029 OG1 THR 217 4.544 -8.051 4.050 1.00 0.00 O +ATOM 2030 HG1 THR 217 4.060 -8.836 3.792 1.00 0.00 H +ATOM 2031 CG2 THR 217 4.550 -7.271 1.758 1.00 0.00 C +ATOM 2032 C THR 217 4.242 -5.109 4.948 1.00 0.00 C +ATOM 2033 O THR 217 4.556 -5.550 6.063 1.00 0.00 O +ATOM 2034 N GLY 218 3.369 -4.117 4.763 1.00 0.00 N +ATOM 2035 H GLY 218 3.139 -3.812 3.868 1.00 0.00 H +ATOM 2036 CA GLY 218 2.671 -3.476 5.867 1.00 0.00 C +ATOM 2037 C GLY 218 1.167 -3.588 5.733 1.00 0.00 C +ATOM 2038 O GLY 218 0.677 -4.275 4.827 1.00 0.00 O +ATOM 2039 N VAL 219 0.442 -2.921 6.640 1.00 0.00 N +ATOM 2040 H VAL 219 0.905 -2.394 7.326 1.00 0.00 H +ATOM 2041 CA VAL 219 -1.029 -2.931 6.670 1.00 0.00 C +ATOM 2042 CB VAL 219 -1.595 -3.615 7.988 1.00 0.00 C +ATOM 2043 CG1 VAL 219 -0.777 -4.835 8.387 1.00 0.00 C +ATOM 2044 CG2 VAL 219 -1.707 -2.639 9.153 1.00 0.00 C +ATOM 2045 C VAL 219 -1.617 -1.511 6.521 1.00 0.00 C +ATOM 2046 O VAL 219 -0.864 -0.535 6.467 1.00 0.00 O +ATOM 2047 N ASN 220 -2.957 -1.412 6.549 1.00 0.00 N +ATOM 2048 H ASN 220 -3.487 -2.236 6.633 1.00 0.00 H +ATOM 2049 CA ASN 220 -3.723 -0.149 6.462 1.00 0.00 C +ATOM 2050 CB ASN 220 -5.219 -0.456 6.172 1.00 0.00 C +ATOM 2051 CG ASN 220 -5.797 -1.572 7.040 1.00 0.00 C +ATOM 2052 OD1 ASN 220 -6.163 -1.358 8.198 1.00 0.00 O +ATOM 2053 ND2 ASN 220 -5.905 -2.765 6.465 1.00 0.00 N +ATOM 2054 HD21 ASN 220 -5.594 -2.877 5.546 1.00 0.00 H +ATOM 2055 HD22 ASN 220 -6.309 -3.493 6.974 1.00 0.00 H +ATOM 2056 C ASN 220 -3.496 0.719 7.748 1.00 0.00 C +ATOM 2057 O ASN 220 -2.606 0.367 8.531 1.00 0.00 O +ATOM 2058 N PRO 221 -4.242 1.853 7.977 1.00 0.00 N +ATOM 2059 CD PRO 221 -5.218 2.603 7.148 1.00 0.00 C +ATOM 2060 CA PRO 221 -3.973 2.626 9.211 1.00 0.00 C +ATOM 2061 CB PRO 221 -4.872 3.856 9.035 1.00 0.00 C +ATOM 2062 CG PRO 221 -5.996 3.360 8.168 1.00 0.00 C +ATOM 2063 C PRO 221 -4.147 1.913 10.591 1.00 0.00 C +ATOM 2064 O PRO 221 -5.157 2.101 11.288 1.00 0.00 O +ATOM 2065 N ALA 222 -3.153 1.077 10.934 1.00 0.00 N +ATOM 2066 H ALA 222 -2.375 0.962 10.349 1.00 0.00 H +ATOM 2067 CA ALA 222 -3.092 0.293 12.184 1.00 0.00 C +ATOM 2068 CB ALA 222 -3.902 -1.022 12.055 1.00 0.00 C +ATOM 2069 C ALA 222 -1.631 -0.025 12.552 1.00 0.00 C +ATOM 2070 O ALA 222 -1.200 0.272 13.672 1.00 0.00 O +ATOM 2071 N SER 223 -0.890 -0.623 11.605 1.00 0.00 N +ATOM 2072 H SER 223 -1.281 -0.809 10.726 1.00 0.00 H +ATOM 2073 CA SER 223 0.523 -1.015 11.779 1.00 0.00 C +ATOM 2074 CB SER 223 0.671 -2.543 11.690 1.00 0.00 C +ATOM 2075 OG SER 223 -0.092 -3.192 12.694 1.00 0.00 O +ATOM 2076 HG SER 223 -1.029 -3.022 12.570 1.00 0.00 H +ATOM 2077 C SER 223 1.462 -0.324 10.769 1.00 0.00 C +ATOM 2078 O SER 223 2.492 -0.891 10.372 1.00 0.00 O +ATOM 2079 N ALA 224 1.112 0.911 10.383 1.00 0.00 N +ATOM 2080 H ALA 224 0.288 1.318 10.731 1.00 0.00 H +ATOM 2081 CA ALA 224 1.892 1.743 9.442 1.00 0.00 C +ATOM 2082 CB ALA 224 1.105 2.972 9.047 1.00 0.00 C +ATOM 2083 C ALA 224 3.229 2.139 10.091 1.00 0.00 C +ATOM 2084 O ALA 224 4.253 2.265 9.408 1.00 0.00 O +ATOM 2085 N HIS 225 3.181 2.340 11.416 1.00 0.00 N +ATOM 2086 H HIS 225 2.319 2.248 11.883 1.00 0.00 H +ATOM 2087 CA HIS 225 4.334 2.695 12.267 1.00 0.00 C +ATOM 2088 CB HIS 225 3.853 3.058 13.689 1.00 0.00 C +ATOM 2089 CG HIS 225 4.778 3.971 14.445 1.00 0.00 C +ATOM 2090 CD2 HIS 225 5.530 3.761 15.554 1.00 0.00 C +ATOM 2091 ND1 HIS 225 4.990 5.286 14.086 1.00 0.00 N +ATOM 2092 HD1 HIS 225 4.583 5.741 13.320 1.00 0.00 H +ATOM 2093 CE1 HIS 225 5.831 5.846 14.937 1.00 0.00 C +ATOM 2094 NE2 HIS 225 6.174 4.941 15.837 1.00 0.00 N +ATOM 2095 HE2 HIS 225 6.788 5.089 16.587 1.00 0.00 H +ATOM 2096 C HIS 225 5.313 1.500 12.311 1.00 0.00 C +ATOM 2097 O HIS 225 6.531 1.700 12.364 1.00 0.00 O +ATOM 2098 N SER 226 4.757 0.276 12.281 1.00 0.00 N +ATOM 2099 H SER 226 3.778 0.197 12.235 1.00 0.00 H +ATOM 2100 CA SER 226 5.516 -0.994 12.307 1.00 0.00 C +ATOM 2101 CB SER 226 4.554 -2.185 12.495 1.00 0.00 C +ATOM 2102 OG SER 226 5.255 -3.399 12.722 1.00 0.00 O +ATOM 2103 HG SER 226 5.796 -3.621 11.960 1.00 0.00 H +ATOM 2104 C SER 226 6.374 -1.188 11.035 1.00 0.00 C +ATOM 2105 O SER 226 7.567 -1.501 11.140 1.00 0.00 O +ATOM 2106 N THR 227 5.774 -0.956 9.856 1.00 0.00 N +ATOM 2107 H THR 227 4.828 -0.690 9.845 1.00 0.00 H +ATOM 2108 CA THR 227 6.460 -1.071 8.549 1.00 0.00 C +ATOM 2109 CB THR 227 5.447 -1.165 7.338 1.00 0.00 C +ATOM 2110 OG1 THR 227 6.166 -1.273 6.102 1.00 0.00 O +ATOM 2111 HG1 THR 227 6.698 -0.486 5.957 1.00 0.00 H +ATOM 2112 CG2 THR 227 4.497 0.033 7.280 1.00 0.00 C +ATOM 2113 C THR 227 7.508 0.052 8.351 1.00 0.00 C +ATOM 2114 O THR 227 8.582 -0.188 7.788 1.00 0.00 O +ATOM 2115 N ALA 228 7.172 1.256 8.841 1.00 0.00 N +ATOM 2116 H ALA 228 6.297 1.385 9.276 1.00 0.00 H +ATOM 2117 CA ALA 228 8.027 2.457 8.772 1.00 0.00 C +ATOM 2118 CB ALA 228 7.227 3.697 9.152 1.00 0.00 C +ATOM 2119 C ALA 228 9.287 2.338 9.651 1.00 0.00 C +ATOM 2120 O ALA 228 10.379 2.725 9.214 1.00 0.00 O +ATOM 2121 N VAL 229 9.125 1.787 10.866 1.00 0.00 N +ATOM 2122 H VAL 229 8.227 1.499 11.146 1.00 0.00 H +ATOM 2123 CA VAL 229 10.231 1.575 11.827 1.00 0.00 C +ATOM 2124 CB VAL 229 9.698 1.319 13.307 1.00 0.00 C +ATOM 2125 CG1 VAL 229 9.021 -0.049 13.460 1.00 0.00 C +ATOM 2126 CG2 VAL 229 10.809 1.528 14.349 1.00 0.00 C +ATOM 2127 C VAL 229 11.196 0.477 11.299 1.00 0.00 C +ATOM 2128 O VAL 229 12.420 0.601 11.433 1.00 0.00 O +ATOM 2129 N ARG 230 10.614 -0.568 10.693 1.00 0.00 N +ATOM 2130 H ARG 230 9.628 -0.613 10.646 1.00 0.00 H +ATOM 2131 CA ARG 230 11.342 -1.701 10.088 1.00 0.00 C +ATOM 2132 CB ARG 230 10.375 -2.850 9.776 1.00 0.00 C +ATOM 2133 CG ARG 230 10.176 -3.826 10.941 1.00 0.00 C +ATOM 2134 CD ARG 230 8.769 -4.438 10.995 1.00 0.00 C +ATOM 2135 NE ARG 230 8.395 -5.187 9.792 1.00 0.00 N +ATOM 2136 HE ARG 230 9.088 -5.343 9.117 1.00 0.00 H +ATOM 2137 CZ ARG 230 7.178 -5.673 9.545 1.00 0.00 C +ATOM 2138 NH1 ARG 230 6.951 -6.333 8.419 1.00 0.00 N +ATOM 2139 HH11 ARG 230 7.691 -6.465 7.759 1.00 0.00 H +ATOM 2140 HH12 ARG 230 6.041 -6.700 8.229 1.00 0.00 H +ATOM 2141 NH2 ARG 230 6.184 -5.512 10.414 1.00 0.00 N +ATOM 2142 HH21 ARG 230 6.343 -5.018 11.269 1.00 0.00 H +ATOM 2143 HH22 ARG 230 5.278 -5.883 10.212 1.00 0.00 H +ATOM 2144 C ARG 230 12.115 -1.279 8.824 1.00 0.00 C +ATOM 2145 O ARG 230 13.233 -1.755 8.593 1.00 0.00 O +ATOM 2146 N SER 231 11.512 -0.371 8.037 1.00 0.00 N +ATOM 2147 H SER 231 10.623 -0.032 8.287 1.00 0.00 H +ATOM 2148 CA SER 231 12.090 0.178 6.792 1.00 0.00 C +ATOM 2149 CB SER 231 11.022 0.938 5.987 1.00 0.00 C +ATOM 2150 OG SER 231 11.493 1.306 4.699 1.00 0.00 O +ATOM 2151 HG SER 231 11.697 0.524 4.180 1.00 0.00 H +ATOM 2152 C SER 231 13.307 1.083 7.071 1.00 0.00 C +ATOM 2153 O SER 231 14.329 0.966 6.383 1.00 0.00 O +ATOM 2154 N ILE 232 13.194 1.959 8.085 1.00 0.00 N +ATOM 2155 H ILE 232 12.355 2.011 8.598 1.00 0.00 H +ATOM 2156 CA ILE 232 14.285 2.876 8.483 1.00 0.00 C +ATOM 2157 CB ILE 232 13.808 4.094 9.377 1.00 0.00 C +ATOM 2158 CG2 ILE 232 12.898 5.010 8.553 1.00 0.00 C +ATOM 2159 CG1 ILE 232 13.112 3.640 10.673 1.00 0.00 C +ATOM 2160 CD1 ILE 232 13.622 4.318 11.949 1.00 0.00 C +ATOM 2161 C ILE 232 15.483 2.123 9.100 1.00 0.00 C +ATOM 2162 O ILE 232 16.639 2.449 8.809 1.00 0.00 O +ATOM 2163 N ASP 233 15.173 1.081 9.887 1.00 0.00 N +ATOM 2164 H ASP 233 14.223 0.871 10.059 1.00 0.00 H +ATOM 2165 CA ASP 233 16.158 0.203 10.552 1.00 0.00 C +ATOM 2166 CB ASP 233 15.446 -0.732 11.552 1.00 0.00 C +ATOM 2167 CG ASP 233 16.358 -1.203 12.688 1.00 0.00 C +ATOM 2168 OD1 ASP 233 16.412 -0.521 13.736 1.00 0.00 O +ATOM 2169 OD2 ASP 233 17.006 -2.262 12.538 1.00 0.00 O +ATOM 2170 C ASP 233 16.891 -0.614 9.466 1.00 0.00 C +ATOM 2171 O ASP 233 18.092 -0.881 9.589 1.00 0.00 O +ATOM 2172 N ALA 234 16.140 -0.995 8.420 1.00 0.00 N +ATOM 2173 H ALA 234 15.181 -0.770 8.397 1.00 0.00 H +ATOM 2174 CA ALA 234 16.630 -1.764 7.259 1.00 0.00 C +ATOM 2175 CB ALA 234 15.457 -2.278 6.432 1.00 0.00 C +ATOM 2176 C ALA 234 17.598 -0.967 6.367 1.00 0.00 C +ATOM 2177 O ALA 234 18.611 -1.518 5.921 1.00 0.00 O +ATOM 2178 N LEU 235 17.279 0.314 6.114 1.00 0.00 N +ATOM 2179 H LEU 235 16.454 0.703 6.481 1.00 0.00 H +ATOM 2180 CA LEU 235 18.112 1.209 5.283 1.00 0.00 C +ATOM 2181 CB LEU 235 17.327 2.472 4.822 1.00 0.00 C +ATOM 2182 CG LEU 235 16.720 3.604 5.679 1.00 0.00 C +ATOM 2183 CD1 LEU 235 17.742 4.698 6.015 1.00 0.00 C +ATOM 2184 CD2 LEU 235 15.553 4.220 4.929 1.00 0.00 C +ATOM 2185 C LEU 235 19.462 1.590 5.927 1.00 0.00 C +ATOM 2186 O LEU 235 20.496 1.531 5.255 1.00 0.00 O +ATOM 2187 N LYS 236 19.436 1.971 7.215 1.00 0.00 N +ATOM 2188 H LYS 236 18.582 2.008 7.707 1.00 0.00 H +ATOM 2189 CA LYS 236 20.645 2.362 7.972 1.00 0.00 C +ATOM 2190 CB LYS 236 20.299 3.171 9.245 1.00 0.00 C +ATOM 2191 CG LYS 236 19.363 2.524 10.284 1.00 0.00 C +ATOM 2192 CD LYS 236 19.268 3.395 11.534 1.00 0.00 C +ATOM 2193 CE LYS 236 18.267 2.851 12.547 1.00 0.00 C +ATOM 2194 NZ LYS 236 16.848 3.055 12.131 1.00 0.00 N +ATOM 2195 HZ1 LYS 236 16.215 2.664 12.858 1.00 0.00 H +ATOM 2196 HZ2 LYS 236 16.678 2.570 11.227 1.00 0.00 H +ATOM 2197 HZ3 LYS 236 16.662 4.072 12.020 1.00 0.00 H +ATOM 2198 C LYS 236 21.641 1.224 8.283 1.00 0.00 C +ATOM 2199 O LYS 236 22.856 1.434 8.219 1.00 0.00 O +ATOM 2200 N ASN 237 21.106 0.031 8.601 1.00 0.00 N +ATOM 2201 H ASN 237 20.128 -0.065 8.622 1.00 0.00 H +ATOM 2202 CA ASN 237 21.850 -1.215 8.941 1.00 0.00 C +ATOM 2203 CB ASN 237 22.567 -1.816 7.710 1.00 0.00 C +ATOM 2204 CG ASN 237 21.600 -2.250 6.614 1.00 0.00 C +ATOM 2205 OD1 ASN 237 21.297 -1.482 5.699 1.00 0.00 O +ATOM 2206 ND2 ASN 237 21.130 -3.493 6.692 1.00 0.00 N +ATOM 2207 HD21 ASN 237 21.416 -4.067 7.434 1.00 0.00 H +ATOM 2208 HD22 ASN 237 20.507 -3.787 5.995 1.00 0.00 H +ATOM 2209 C ASN 237 22.831 -1.139 10.128 1.00 0.00 C +ATOM 2210 O ASN 237 23.531 -0.133 10.292 1.00 0.00 O +ATOM 2211 N HIS 238 22.878 -2.226 10.920 1.00 0.00 N +ATOM 2212 H HIS 238 22.302 -2.995 10.711 1.00 0.00 H +ATOM 2213 CA HIS 238 23.726 -2.432 12.129 1.00 0.00 C +ATOM 2214 CB HIS 238 24.980 -3.300 11.809 1.00 0.00 C +ATOM 2215 CG HIS 238 25.828 -2.791 10.674 1.00 0.00 C +ATOM 2216 CD2 HIS 238 27.085 -2.284 10.657 1.00 0.00 C +ATOM 2217 ND1 HIS 238 25.399 -2.789 9.364 1.00 0.00 N +ATOM 2218 HD1 HIS 238 24.525 -3.100 9.048 1.00 0.00 H +ATOM 2219 CE1 HIS 238 26.352 -2.304 8.588 1.00 0.00 C +ATOM 2220 NE2 HIS 238 27.386 -1.990 9.349 1.00 0.00 N +ATOM 2221 HE2 HIS 238 28.231 -1.608 9.031 1.00 0.00 H +ATOM 2222 C HIS 238 24.093 -1.239 13.047 1.00 0.00 C +ATOM 2223 O HIS 238 23.693 -1.219 14.217 1.00 0.00 O +ATOM 2224 N HIS 239 24.844 -0.263 12.502 1.00 0.00 N +ATOM 2225 H HIS 239 25.121 -0.345 11.563 1.00 0.00 H +ATOM 2226 CA HIS 239 25.325 0.976 13.176 1.00 0.00 C +ATOM 2227 CB HIS 239 24.149 1.928 13.529 1.00 0.00 C +ATOM 2228 CG HIS 239 24.492 3.391 13.469 1.00 0.00 C +ATOM 2229 CD2 HIS 239 24.572 4.330 14.443 1.00 0.00 C +ATOM 2230 ND1 HIS 239 24.781 4.044 12.288 1.00 0.00 N +ATOM 2231 HD1 HIS 239 24.804 3.632 11.399 1.00 0.00 H +ATOM 2232 CE1 HIS 239 25.025 5.318 12.537 1.00 0.00 C +ATOM 2233 NE2 HIS 239 24.904 5.517 13.837 1.00 0.00 N +ATOM 2234 HE2 HIS 239 25.031 6.374 14.296 1.00 0.00 H +ATOM 2235 C HIS 239 26.229 0.738 14.411 1.00 0.00 C +ATOM 2236 O HIS 239 25.939 -0.135 15.239 1.00 0.00 O +ATOM 2237 N HIS 240 27.310 1.525 14.508 1.00 0.00 N +ATOM 2238 H HIS 240 27.493 2.204 13.823 1.00 0.00 H +ATOM 2239 CA HIS 240 28.292 1.452 15.608 1.00 0.00 C +ATOM 2240 CB HIS 240 29.742 1.420 15.056 1.00 0.00 C +ATOM 2241 CG HIS 240 30.042 2.461 14.010 1.00 0.00 C +ATOM 2242 CD2 HIS 240 30.327 2.343 12.690 1.00 0.00 C +ATOM 2243 ND1 HIS 240 30.089 3.810 14.289 1.00 0.00 N +ATOM 2244 HD1 HIS 240 29.926 4.218 15.165 1.00 0.00 H +ATOM 2245 CE1 HIS 240 30.389 4.478 13.190 1.00 0.00 C +ATOM 2246 NE2 HIS 240 30.539 3.611 12.205 1.00 0.00 N +ATOM 2247 HE2 HIS 240 30.765 3.835 11.278 1.00 0.00 H +ATOM 2248 C HIS 240 28.126 2.567 16.660 1.00 0.00 C +ATOM 2249 O HIS 240 27.695 3.676 16.323 1.00 0.00 O +ATOM 2250 N HIS 241 28.470 2.251 17.917 1.00 0.00 N +ATOM 2251 H HIS 241 28.807 1.353 18.128 1.00 0.00 H +ATOM 2252 CA HIS 241 28.381 3.180 19.060 1.00 0.00 C +ATOM 2253 CB HIS 241 27.678 2.504 20.254 1.00 0.00 C +ATOM 2254 CG HIS 241 26.240 2.149 20.004 1.00 0.00 C +ATOM 2255 CD2 HIS 241 25.094 2.628 20.549 1.00 0.00 C +ATOM 2256 ND1 HIS 241 25.855 1.171 19.110 1.00 0.00 N +ATOM 2257 HD1 HIS 241 26.459 0.635 18.555 1.00 0.00 H +ATOM 2258 CE1 HIS 241 24.538 1.064 19.114 1.00 0.00 C +ATOM 2259 NE2 HIS 241 24.053 1.937 19.978 1.00 0.00 N +ATOM 2260 HE2 HIS 241 23.103 2.070 20.180 1.00 0.00 H +ATOM 2261 C HIS 241 29.767 3.683 19.493 1.00 0.00 C +ATOM 2262 O HIS 241 30.762 2.964 19.339 1.00 0.00 O +ATOM 2263 N HIS 242 29.813 4.913 20.027 1.00 0.00 N +ATOM 2264 H HIS 242 28.991 5.442 20.125 1.00 0.00 H +ATOM 2265 CA HIS 242 31.049 5.566 20.500 1.00 0.00 C +ATOM 2266 CB HIS 242 31.140 7.008 19.962 1.00 0.00 C +ATOM 2267 CG HIS 242 31.271 7.103 18.468 1.00 0.00 C +ATOM 2268 CD2 HIS 242 30.425 7.589 17.527 1.00 0.00 C +ATOM 2269 ND1 HIS 242 32.395 6.684 17.788 1.00 0.00 N +ATOM 2270 HD1 HIS 242 33.192 6.283 18.194 1.00 0.00 H +ATOM 2271 CE1 HIS 242 32.237 6.905 16.495 1.00 0.00 C +ATOM 2272 NE2 HIS 242 31.050 7.454 16.310 1.00 0.00 N +ATOM 2273 HE2 HIS 242 30.675 7.722 15.445 1.00 0.00 H +ATOM 2274 C HIS 242 31.136 5.580 22.035 1.00 0.00 C +ATOM 2275 O HIS 242 32.235 5.473 22.593 1.00 0.00 O +ATOM 2276 N HIS 243 29.975 5.706 22.694 1.00 0.00 N +ATOM 2277 H HIS 243 29.130 5.784 22.200 1.00 0.00 H +ATOM 2278 CA HIS 243 29.856 5.740 24.165 1.00 0.00 C +ATOM 2279 CB HIS 243 29.016 6.954 24.615 1.00 0.00 C +ATOM 2280 CG HIS 243 29.642 8.285 24.310 1.00 0.00 C +ATOM 2281 CD2 HIS 243 30.127 9.251 25.128 1.00 0.00 C +ATOM 2282 ND1 HIS 243 29.803 8.760 23.025 1.00 0.00 N +ATOM 2283 HD1 HIS 243 29.547 8.287 22.206 1.00 0.00 H +ATOM 2284 CE1 HIS 243 30.360 9.957 23.064 1.00 0.00 C +ATOM 2285 NE2 HIS 243 30.567 10.278 24.328 1.00 0.00 N +ATOM 2286 HE2 HIS 243 30.969 11.114 24.645 1.00 0.00 H +ATOM 2287 C HIS 243 29.239 4.450 24.710 1.00 0.00 C +ATOM 2288 O HIS 243 28.389 3.861 24.009 1.00 0.00 O +ATOM 2289 OXT HIS 243 29.623 4.040 25.827 1.00 0.00 O +END diff --git a/examples/testdata/raptorxeg/models/195600_model_3.pdb b/examples/testdata/raptorxeg/models/195600_model_3.pdb new file mode 100644 index 0000000..6ba9576 --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600_model_3.pdb @@ -0,0 +1,2358 @@ +REMARK FILENAME="7_195600_9.pdb" +REMARK The macromolecule has 243 residues +REMARK Trial structure 9 of 10 structures +REMARK Molecular dynamics scheme : cartesian; cartesian; minimize +REMARK High temperature dynamics : +REMARK temp: 2000 steps: 1000 time(ps): 3 +REMARK 1st cooling stage : +REMARK temp: 2000->0 steps: 1000 time(ps): 5 temp step: 25 +REMARK 2nd cooling stage not used: +REMARK a total 36450 steps of minimization +REMARK VDW scale factors 20 20 0.01 0.003 0.003; 3E-03->4; 1 +REMARK 1072 NOEs in 3 class(es) with scale factors of 10; 10; 10 +REMARK averaging function(s): cent, sum, hbnd: cent +REMARK 0 3-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 1-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 carbon chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 proton chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 diffusion anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 susceptability anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 188 dihedral restraints with scale factors of 5; 50; 50 +REMARK 0 planarity restraints with a scale factor of NA +REMARK NCS restraints not used. +REMARK =============================================================== +REMARK bond, angles, improp, vdw(<1.6), dihed +REMARK violations : 19 200 22 7 311 +REMARK RMSD : 0.0169 2.413 1.595 23.726 +REMARK =============================================================== +REMARK noe, cdih, coup, oneb, carb-a, carb-b, +REMARK violations : 119 11 0 0 0 ----- +REMARK RMSD : 0.591 2.345 0.000 0.000 0.000 0.000 +REMARK 0.2/2 viol.: 257 41 0 +REMARK =============================================================== +REMARK dani, sani +REMARK violations : 0 0 +REMARK RMSD : 0.000 0.000 +REMARK .2/.1 viol.: 0 0 +REMARK =============================================================== +REMARK Protons violations, rmsd +REMARK all : 0 0.000 +REMARK class 1: 0 0.000 +REMARK class 2: 0 0.000 +REMARK class 3: 0 0.000 +REMARK class 4: 0 0.000 +REMARK =============================================================== +REMARK overall = 13032.1 +REMARK bon = 831.697 +REMARK ang = 1390.3 +REMARK imp = 257.914 +REMARK vdw = 8027.36 +REMARK harm = 0 +REMARK noe = 1666.78 +REMARK coup = 0 +REMARK oneb = 0 +REMARK carb = 0 +REMARK prot = 0 +REMARK dani = 0 +REMARK sani = 0 +REMARK cdih = 78.7111 +REMARK ncs = 0 +REMARK =============================================================== +REMARK DATE:15-Jan-2017 12:37:41 created by user: RaptorX +REMARK VERSION:1.3 +ATOM 1 CB MET 1 17.207 18.389 8.010 1.00 0.00 C +ATOM 2 CG MET 1 16.371 19.400 8.807 1.00 0.00 C +ATOM 3 SD MET 1 14.596 19.402 8.432 1.00 0.00 S +ATOM 4 CE MET 1 14.443 20.920 7.488 1.00 0.00 C +ATOM 5 C MET 1 18.505 17.803 5.938 1.00 0.00 C +ATOM 6 O MET 1 19.687 18.165 5.897 1.00 0.00 O +ATOM 7 HT1 MET 1 15.453 19.271 6.179 1.00 0.00 H +ATOM 8 HT2 MET 1 16.329 18.905 4.772 1.00 0.00 H +ATOM 9 N MET 1 16.160 18.635 5.762 1.00 0.00 N +ATOM 10 HT3 MET 1 15.810 17.656 5.799 1.00 0.00 H +ATOM 11 CA MET 1 17.437 18.734 6.529 1.00 0.00 C +ATOM 12 N ALA 2 18.073 16.616 5.488 1.00 0.00 N +ATOM 13 H ALA 2 17.121 16.381 5.544 1.00 0.00 H +ATOM 14 CA ALA 2 18.944 15.589 4.890 1.00 0.00 C +ATOM 15 CB ALA 2 18.914 14.314 5.741 1.00 0.00 C +ATOM 16 C ALA 2 18.497 15.274 3.443 1.00 0.00 C +ATOM 17 O ALA 2 17.327 15.498 3.114 1.00 0.00 O +ATOM 18 N PRO 3 19.418 14.773 2.556 1.00 0.00 N +ATOM 19 CD PRO 3 20.891 14.723 2.713 1.00 0.00 C +ATOM 20 CA PRO 3 19.077 14.438 1.153 1.00 0.00 C +ATOM 21 CB PRO 3 20.445 14.124 0.542 1.00 0.00 C +ATOM 22 CG PRO 3 21.372 14.981 1.312 1.00 0.00 C +ATOM 23 C PRO 3 18.108 13.244 0.964 1.00 0.00 C +ATOM 24 O PRO 3 17.481 12.794 1.930 1.00 0.00 O +ATOM 25 N LYS 4 18.003 12.753 -0.286 1.00 0.00 N +ATOM 26 H LYS 4 18.523 13.170 -1.008 1.00 0.00 H +ATOM 27 CA LYS 4 17.161 11.609 -0.726 1.00 0.00 C +ATOM 28 CB LYS 4 17.641 10.281 -0.105 1.00 0.00 C +ATOM 29 CG LYS 4 19.015 9.829 -0.604 1.00 0.00 C +ATOM 30 CD LYS 4 19.494 8.564 0.097 1.00 0.00 C +ATOM 31 CE LYS 4 20.866 8.112 -0.401 1.00 0.00 C +ATOM 32 NZ LYS 4 21.976 9.032 -0.011 1.00 0.00 N +ATOM 33 HZ1 LYS 4 21.798 9.978 -0.407 1.00 0.00 H +ATOM 34 HZ2 LYS 4 22.876 8.666 -0.381 1.00 0.00 H +ATOM 35 HZ3 LYS 4 22.027 9.094 1.026 1.00 0.00 H +ATOM 36 C LYS 4 15.636 11.773 -0.572 1.00 0.00 C +ATOM 37 O LYS 4 15.164 12.265 0.461 1.00 0.00 O +ATOM 38 N LYS 5 14.894 11.362 -1.611 1.00 0.00 N +ATOM 39 H LYS 5 15.324 10.965 -2.401 1.00 0.00 H +ATOM 40 CA LYS 5 13.421 11.455 -1.676 1.00 0.00 C +ATOM 41 CB LYS 5 12.986 12.218 -2.937 1.00 0.00 C +ATOM 42 CG LYS 5 13.368 13.694 -2.963 1.00 0.00 C +ATOM 43 CD LYS 5 12.897 14.366 -4.248 1.00 0.00 C +ATOM 44 CE LYS 5 13.269 15.847 -4.295 1.00 0.00 C +ATOM 45 NZ LYS 5 14.737 16.090 -4.426 1.00 0.00 N +ATOM 46 HZ1 LYS 5 15.084 15.655 -5.304 1.00 0.00 H +ATOM 47 HZ2 LYS 5 15.232 15.671 -3.613 1.00 0.00 H +ATOM 48 HZ3 LYS 5 14.918 17.114 -4.452 1.00 0.00 H +ATOM 49 C LYS 5 12.692 10.103 -1.643 1.00 0.00 C +ATOM 50 O LYS 5 13.168 9.122 -2.229 1.00 0.00 O +ATOM 51 N VAL 6 11.541 10.075 -0.953 1.00 0.00 N +ATOM 52 H VAL 6 11.214 10.879 -0.502 1.00 0.00 H +ATOM 53 CA VAL 6 10.670 8.889 -0.818 1.00 0.00 C +ATOM 54 CB VAL 6 10.554 8.406 0.715 1.00 0.00 C +ATOM 55 CG1 VAL 6 9.921 9.476 1.625 1.00 0.00 C +ATOM 56 CG2 VAL 6 9.820 7.063 0.835 1.00 0.00 C +ATOM 57 C VAL 6 9.301 9.220 -1.479 1.00 0.00 C +ATOM 58 O VAL 6 8.705 10.264 -1.180 1.00 0.00 O +ATOM 59 N LEU 7 8.852 8.353 -2.398 1.00 0.00 N +ATOM 60 H LEU 7 9.376 7.555 -2.627 1.00 0.00 H +ATOM 61 CA LEU 7 7.574 8.523 -3.117 1.00 0.00 C +ATOM 62 CB LEU 7 7.802 8.716 -4.646 1.00 0.00 C +ATOM 63 CG LEU 7 8.640 7.841 -5.605 1.00 0.00 C +ATOM 64 CD1 LEU 7 7.771 6.802 -6.318 1.00 0.00 C +ATOM 65 CD2 LEU 7 9.281 8.742 -6.645 1.00 0.00 C +ATOM 66 C LEU 7 6.552 7.405 -2.826 1.00 0.00 C +ATOM 67 O LEU 7 6.882 6.217 -2.933 1.00 0.00 O +ATOM 68 N LEU 8 5.334 7.808 -2.434 1.00 0.00 N +ATOM 69 H LEU 8 5.132 8.765 -2.346 1.00 0.00 H +ATOM 70 CA LEU 8 4.222 6.893 -2.110 1.00 0.00 C +ATOM 71 CB LEU 8 3.847 6.982 -0.596 1.00 0.00 C +ATOM 72 CG LEU 8 3.700 8.195 0.373 1.00 0.00 C +ATOM 73 CD1 LEU 8 5.045 8.896 0.625 1.00 0.00 C +ATOM 74 CD2 LEU 8 2.619 9.197 -0.072 1.00 0.00 C +ATOM 75 C LEU 8 2.986 7.125 -2.998 1.00 0.00 C +ATOM 76 O LEU 8 2.621 8.278 -3.258 1.00 0.00 O +ATOM 77 N ALA 9 2.354 6.027 -3.437 1.00 0.00 N +ATOM 78 H ALA 9 2.678 5.134 -3.188 1.00 0.00 H +ATOM 79 CA ALA 9 1.160 6.055 -4.302 1.00 0.00 C +ATOM 80 CB ALA 9 1.393 5.211 -5.558 1.00 0.00 C +ATOM 81 C ALA 9 -0.119 5.600 -3.582 1.00 0.00 C +ATOM 82 O ALA 9 -0.090 4.629 -2.816 1.00 0.00 O +ATOM 83 N LEU 10 -1.224 6.318 -3.836 1.00 0.00 N +ATOM 84 H LEU 10 -1.188 7.085 -4.450 1.00 0.00 H +ATOM 85 CA LEU 10 -2.550 6.044 -3.247 1.00 0.00 C +ATOM 86 CB LEU 10 -3.023 7.230 -2.370 1.00 0.00 C +ATOM 87 CG LEU 10 -2.306 7.608 -1.060 1.00 0.00 C +ATOM 88 CD1 LEU 10 -1.343 8.792 -1.255 1.00 0.00 C +ATOM 89 CD2 LEU 10 -3.355 7.975 -0.023 1.00 0.00 C +ATOM 90 C LEU 10 -3.600 5.761 -4.333 1.00 0.00 C +ATOM 91 O LEU 10 -3.445 6.205 -5.476 1.00 0.00 O +ATOM 92 N THR 11 -4.656 5.021 -3.957 1.00 0.00 N +ATOM 93 H THR 11 -4.717 4.719 -3.025 1.00 0.00 H +ATOM 94 CA THR 11 -5.787 4.644 -4.838 1.00 0.00 C +ATOM 95 OG1 THR 11 -7.678 3.096 -4.271 1.00 0.00 O +ATOM 96 HG1 THR 11 -8.184 3.389 -5.031 1.00 0.00 H +ATOM 97 CG2 THR 11 -5.492 2.465 -3.456 1.00 0.00 C +ATOM 98 C THR 11 -6.919 5.680 -4.631 1.00 0.00 C +ATOM 99 O THR 11 -6.664 6.739 -4.047 1.00 0.00 O +ATOM 100 CB THR 11 -6.277 3.139 -4.577 1.00 0.00 C +ATOM 101 N SER 12 -8.132 5.397 -5.126 1.00 0.00 N +ATOM 102 H SER 12 -8.280 4.568 -5.629 1.00 0.00 H +ATOM 103 CA SER 12 -9.293 6.284 -4.969 1.00 0.00 C +ATOM 104 CB SER 12 -9.836 6.720 -6.332 1.00 0.00 C +ATOM 105 OG SER 12 -8.847 7.407 -7.079 1.00 0.00 O +ATOM 106 HG SER 12 -8.108 6.827 -7.281 1.00 0.00 H +ATOM 107 C SER 12 -10.400 5.597 -4.156 1.00 0.00 C +ATOM 108 O SER 12 -11.139 6.271 -3.431 1.00 0.00 O +ATOM 109 N TYR 13 -10.467 4.261 -4.253 1.00 0.00 N +ATOM 110 H TYR 13 -9.823 3.772 -4.811 1.00 0.00 H +ATOM 111 CA TYR 13 -11.469 3.424 -3.562 1.00 0.00 C +ATOM 112 CB TYR 13 -12.127 2.447 -4.564 1.00 0.00 C +ATOM 113 CG TYR 13 -12.871 3.067 -5.753 1.00 0.00 C +ATOM 114 CD1 TYR 13 -12.191 3.396 -6.953 1.00 0.00 C +ATOM 115 CE1 TYR 13 -12.885 3.938 -8.071 1.00 0.00 C +ATOM 116 CD2 TYR 13 -14.268 3.295 -5.702 1.00 0.00 C +ATOM 117 CE2 TYR 13 -14.970 3.837 -6.815 1.00 0.00 C +ATOM 118 CZ TYR 13 -14.270 4.153 -7.991 1.00 0.00 C +ATOM 119 OH TYR 13 -14.948 4.677 -9.068 1.00 0.00 O +ATOM 120 HH TYR 13 -14.343 4.842 -9.795 1.00 0.00 H +ATOM 121 C TYR 13 -10.896 2.617 -2.385 1.00 0.00 C +ATOM 122 O TYR 13 -9.767 2.122 -2.469 1.00 0.00 O +ATOM 123 N ASN 14 -11.681 2.505 -1.301 1.00 0.00 N +ATOM 124 H ASN 14 -12.563 2.938 -1.285 1.00 0.00 H +ATOM 125 CA ASN 14 -11.325 1.759 -0.073 1.00 0.00 C +ATOM 126 CB ASN 14 -10.754 2.715 1.011 1.00 0.00 C +ATOM 127 CG ASN 14 -10.175 1.987 2.227 1.00 0.00 C +ATOM 128 OD1 ASN 14 -10.911 1.531 3.106 1.00 0.00 O +ATOM 129 ND2 ASN 14 -8.852 1.912 2.295 1.00 0.00 N +ATOM 130 HD21 ASN 14 -8.309 2.315 1.590 1.00 0.00 H +ATOM 131 HD22 ASN 14 -8.467 1.446 3.066 1.00 0.00 H +ATOM 132 C ASN 14 -12.579 1.012 0.443 1.00 0.00 C +ATOM 133 O ASN 14 -12.696 -0.200 0.239 1.00 0.00 O +ATOM 134 N ASP 15 -13.528 1.754 1.037 1.00 0.00 N +ATOM 135 H ASP 15 -13.393 2.727 1.098 1.00 0.00 H +ATOM 136 CA ASP 15 -14.784 1.226 1.617 1.00 0.00 C +ATOM 137 CB ASP 15 -15.587 2.372 2.262 1.00 0.00 C +ATOM 138 CG ASP 15 -14.901 2.960 3.491 1.00 0.00 C +ATOM 139 OD1 ASP 15 -15.180 2.488 4.615 1.00 0.00 O +ATOM 140 OD2 ASP 15 -14.097 3.906 3.337 1.00 0.00 O +ATOM 141 C ASP 15 -15.689 0.437 0.649 1.00 0.00 C +ATOM 142 O ASP 15 -15.487 0.495 -0.567 1.00 0.00 O +ATOM 143 N VAL 16 -16.645 -0.326 1.215 1.00 0.00 N +ATOM 144 H VAL 16 -16.716 -0.350 2.195 1.00 0.00 H +ATOM 145 CA VAL 16 -17.656 -1.178 0.520 1.00 0.00 C +ATOM 146 CB VAL 16 -18.869 -0.331 -0.090 1.00 0.00 C +ATOM 147 CG1 VAL 16 -20.094 -1.221 -0.371 1.00 0.00 C +ATOM 148 CG2 VAL 16 -19.269 0.804 0.853 1.00 0.00 C +ATOM 149 C VAL 16 -17.102 -2.181 -0.530 1.00 0.00 C +ATOM 150 O VAL 16 -16.182 -1.857 -1.291 1.00 0.00 O +ATOM 151 N PHE 17 -17.687 -3.388 -0.546 1.00 0.00 N +ATOM 152 H PHE 17 -18.412 -3.595 0.084 1.00 0.00 H +ATOM 153 CA PHE 17 -17.322 -4.479 -1.468 1.00 0.00 C +ATOM 154 CB PHE 17 -17.157 -5.807 -0.673 1.00 0.00 C +ATOM 155 CG PHE 17 -16.315 -6.879 -1.373 1.00 0.00 C +ATOM 156 CD1 PHE 17 -16.919 -7.828 -2.234 1.00 0.00 C +ATOM 157 CD2 PHE 17 -14.921 -6.968 -1.145 1.00 0.00 C +ATOM 158 CE1 PHE 17 -16.149 -8.847 -2.858 1.00 0.00 C +ATOM 159 CE2 PHE 17 -14.139 -7.982 -1.762 1.00 0.00 C +ATOM 160 CZ PHE 17 -14.755 -8.923 -2.621 1.00 0.00 C +ATOM 161 C PHE 17 -18.425 -4.610 -2.544 1.00 0.00 C +ATOM 162 O PHE 17 -18.200 -5.217 -3.600 1.00 0.00 O +ATOM 163 N TYR 18 -19.591 -4.012 -2.261 1.00 0.00 N +ATOM 164 H TYR 18 -19.707 -3.532 -1.412 1.00 0.00 H +ATOM 165 CA TYR 18 -20.771 -4.009 -3.146 1.00 0.00 C +ATOM 166 CB TYR 18 -22.048 -4.346 -2.330 1.00 0.00 C +ATOM 167 CG TYR 18 -22.100 -5.731 -1.673 1.00 0.00 C +ATOM 168 CD1 TYR 18 -21.623 -5.934 -0.354 1.00 0.00 C +ATOM 169 CE1 TYR 18 -21.702 -7.209 0.272 1.00 0.00 C +ATOM 170 CD2 TYR 18 -22.661 -6.842 -2.352 1.00 0.00 C +ATOM 171 CE2 TYR 18 -22.744 -8.121 -1.733 1.00 0.00 C +ATOM 172 CZ TYR 18 -22.263 -8.292 -0.425 1.00 0.00 C +ATOM 173 OH TYR 18 -22.343 -9.528 0.175 1.00 0.00 O +ATOM 174 HH TYR 18 -21.977 -9.493 1.062 1.00 0.00 H +ATOM 175 C TYR 18 -20.922 -2.642 -3.847 1.00 0.00 C +ATOM 176 O TYR 18 -20.117 -1.736 -3.601 1.00 0.00 O +ATOM 177 N SER 19 -21.946 -2.508 -4.705 1.00 0.00 N +ATOM 178 H SER 19 -22.557 -3.263 -4.854 1.00 0.00 H +ATOM 179 CA SER 19 -22.238 -1.276 -5.465 1.00 0.00 C +ATOM 180 CB SER 19 -22.953 -1.624 -6.775 1.00 0.00 C +ATOM 181 OG SER 19 -22.155 -2.468 -7.587 1.00 0.00 O +ATOM 182 HG SER 19 -22.004 -3.312 -7.154 1.00 0.00 H +ATOM 183 C SER 19 -23.070 -0.251 -4.674 1.00 0.00 C +ATOM 184 O SER 19 -23.880 -0.635 -3.822 1.00 0.00 O +ATOM 185 N ASP 20 -22.857 1.044 -4.973 1.00 0.00 N +ATOM 186 H ASP 20 -22.201 1.275 -5.667 1.00 0.00 H +ATOM 187 CA ASP 20 -23.525 2.223 -4.352 1.00 0.00 C +ATOM 188 CB ASP 20 -25.017 2.323 -4.751 1.00 0.00 C +ATOM 189 CG ASP 20 -25.218 2.554 -6.245 1.00 0.00 C +ATOM 190 OD1 ASP 20 -25.277 3.729 -6.668 1.00 0.00 O +ATOM 191 OD2 ASP 20 -25.336 1.559 -6.995 1.00 0.00 O +ATOM 192 C ASP 20 -23.370 2.371 -2.827 1.00 0.00 C +ATOM 193 O ASP 20 -23.569 1.405 -2.079 1.00 0.00 O +ATOM 194 N GLY 21 -22.999 3.580 -2.393 1.00 0.00 N +ATOM 195 H GLY 21 -22.839 4.320 -3.019 1.00 0.00 H +ATOM 196 CA GLY 21 -22.809 3.877 -0.977 1.00 0.00 C +ATOM 197 C GLY 21 -21.378 4.264 -0.645 1.00 0.00 C +ATOM 198 O GLY 21 -20.705 3.549 0.105 1.00 0.00 O +ATOM 199 N ALA 22 -20.934 5.408 -1.193 1.00 0.00 N +ATOM 200 H ALA 22 -21.555 5.915 -1.759 1.00 0.00 H +ATOM 201 CA ALA 22 -19.581 6.002 -1.034 1.00 0.00 C +ATOM 202 CB ALA 22 -19.277 6.355 0.447 1.00 0.00 C +ATOM 203 C ALA 22 -18.417 5.197 -1.636 1.00 0.00 C +ATOM 204 O ALA 22 -17.616 5.749 -2.400 1.00 0.00 O +ATOM 205 N LYS 23 -18.351 3.897 -1.294 1.00 0.00 N +ATOM 206 H LYS 23 -19.022 3.517 -0.694 1.00 0.00 H +ATOM 207 CA LYS 23 -17.326 2.903 -1.724 1.00 0.00 C +ATOM 208 CB LYS 23 -17.779 2.092 -2.978 1.00 0.00 C +ATOM 209 CG LYS 23 -18.190 2.882 -4.238 1.00 0.00 C +ATOM 210 CD LYS 23 -18.645 1.946 -5.353 1.00 0.00 C +ATOM 211 CE LYS 23 -19.125 2.707 -6.587 1.00 0.00 C +ATOM 212 NZ LYS 23 -18.034 3.425 -7.312 1.00 0.00 N +ATOM 213 HZ1 LYS 23 -17.319 2.740 -7.629 1.00 0.00 H +ATOM 214 HZ2 LYS 23 -17.592 4.118 -6.674 1.00 0.00 H +ATOM 215 HZ3 LYS 23 -18.432 3.918 -8.136 1.00 0.00 H +ATOM 216 C LYS 23 -15.833 3.334 -1.799 1.00 0.00 C +ATOM 217 O LYS 23 -14.990 2.611 -2.351 1.00 0.00 O +ATOM 218 N THR 24 -15.531 4.491 -1.191 1.00 0.00 N +ATOM 219 H THR 24 -16.218 5.004 -0.716 1.00 0.00 H +ATOM 220 CA THR 24 -14.183 5.088 -1.146 1.00 0.00 C +ATOM 221 CB THR 24 -14.114 6.408 -1.980 1.00 0.00 C +ATOM 222 OG1 THR 24 -15.154 7.304 -1.563 1.00 0.00 O +ATOM 223 HG1 THR 24 -16.018 6.922 -1.737 1.00 0.00 H +ATOM 224 CG2 THR 24 -14.270 6.120 -3.470 1.00 0.00 C +ATOM 225 C THR 24 -13.770 5.387 0.306 1.00 0.00 C +ATOM 226 O THR 24 -14.632 5.460 1.189 1.00 0.00 O +ATOM 227 N GLY 25 -12.462 5.553 0.535 1.00 0.00 N +ATOM 228 H GLY 25 -11.806 5.482 -0.192 1.00 0.00 H +ATOM 229 CA GLY 25 -11.940 5.847 1.864 1.00 0.00 C +ATOM 230 C GLY 25 -10.556 6.461 1.828 1.00 0.00 C +ATOM 231 O GLY 25 -10.144 6.964 0.777 1.00 0.00 O +ATOM 232 N VAL 26 -9.838 6.415 2.963 1.00 0.00 N +ATOM 233 H VAL 26 -10.219 5.969 3.748 1.00 0.00 H +ATOM 234 CA VAL 26 -8.490 7.011 3.086 1.00 0.00 C +ATOM 235 CB VAL 26 -8.520 8.393 3.839 1.00 0.00 C +ATOM 236 CG1 VAL 26 -9.181 9.448 3.000 1.00 0.00 C +ATOM 237 CG2 VAL 26 -9.250 8.275 5.185 1.00 0.00 C +ATOM 238 C VAL 26 -7.276 6.189 3.603 1.00 0.00 C +ATOM 239 O VAL 26 -7.219 5.769 4.769 1.00 0.00 O +ATOM 240 N PHE 27 -6.375 5.907 2.656 1.00 0.00 N +ATOM 241 H PHE 27 -6.582 6.227 1.753 1.00 0.00 H +ATOM 242 CA PHE 27 -5.072 5.215 2.782 1.00 0.00 C +ATOM 243 CG PHE 27 -5.704 4.514 0.389 1.00 0.00 C +ATOM 244 CD1 PHE 27 -6.419 3.297 0.358 1.00 0.00 C +ATOM 245 CD2 PHE 27 -6.097 5.545 -0.488 1.00 0.00 C +ATOM 246 CE1 PHE 27 -7.508 3.113 -0.521 1.00 0.00 C +ATOM 247 CE2 PHE 27 -7.182 5.371 -1.365 1.00 0.00 C +ATOM 248 CZ PHE 27 -7.890 4.159 -1.383 1.00 0.00 C +ATOM 249 C PHE 27 -4.065 6.168 3.441 1.00 0.00 C +ATOM 250 O PHE 27 -3.066 5.736 4.030 1.00 0.00 O +ATOM 251 CB PHE 27 -4.583 4.745 1.393 1.00 0.00 C +ATOM 252 N VAL 28 -4.346 7.471 3.283 1.00 0.00 N +ATOM 253 H VAL 28 -5.175 7.709 2.806 1.00 0.00 H +ATOM 254 CA VAL 28 -3.526 8.602 3.760 1.00 0.00 C +ATOM 255 CB VAL 28 -4.214 9.995 3.412 1.00 0.00 C +ATOM 256 CG1 VAL 28 -5.385 10.324 4.342 1.00 0.00 C +ATOM 257 CG2 VAL 28 -3.182 11.129 3.354 1.00 0.00 C +ATOM 258 C VAL 28 -3.104 8.490 5.248 1.00 0.00 C +ATOM 259 O VAL 28 -2.054 9.020 5.612 1.00 0.00 O +ATOM 260 N VAL 29 -3.934 7.849 6.085 1.00 0.00 N +ATOM 261 H VAL 29 -4.778 7.499 5.724 1.00 0.00 H +ATOM 262 CA VAL 29 -3.635 7.628 7.523 1.00 0.00 C +ATOM 263 CB VAL 29 -4.841 6.953 8.292 1.00 0.00 C +ATOM 264 CG1 VAL 29 -4.756 7.236 9.802 1.00 0.00 C +ATOM 265 CG2 VAL 29 -6.187 7.433 7.748 1.00 0.00 C +ATOM 266 C VAL 29 -2.373 6.723 7.615 1.00 0.00 C +ATOM 267 O VAL 29 -1.477 6.983 8.433 1.00 0.00 O +ATOM 268 N GLU 30 -2.301 5.718 6.721 1.00 0.00 N +ATOM 269 H GLU 30 -3.031 5.585 6.078 1.00 0.00 H +ATOM 270 CA GLU 30 -1.171 4.766 6.626 1.00 0.00 C +ATOM 271 CB GLU 30 -1.474 3.605 5.654 1.00 0.00 C +ATOM 272 CG GLU 30 -2.751 2.829 5.936 1.00 0.00 C +ATOM 273 CD GLU 30 -2.941 1.654 4.997 1.00 0.00 C +ATOM 274 OE1 GLU 30 -2.454 0.550 5.321 1.00 0.00 O +ATOM 275 OE2 GLU 30 -3.578 1.832 3.937 1.00 0.00 O +ATOM 276 C GLU 30 0.046 5.550 6.125 1.00 0.00 C +ATOM 277 O GLU 30 1.146 5.374 6.643 1.00 0.00 O +ATOM 278 N ALA 31 -0.194 6.451 5.161 1.00 0.00 N +ATOM 279 H ALA 31 -1.108 6.549 4.802 1.00 0.00 H +ATOM 280 CA ALA 31 0.825 7.333 4.556 1.00 0.00 C +ATOM 281 CB ALA 31 0.257 8.036 3.323 1.00 0.00 C +ATOM 282 C ALA 31 1.323 8.367 5.579 1.00 0.00 C +ATOM 283 O ALA 31 2.512 8.695 5.596 1.00 0.00 O +ATOM 284 N LEU 32 0.404 8.815 6.453 1.00 0.00 N +ATOM 285 H LEU 32 -0.496 8.433 6.426 1.00 0.00 H +ATOM 286 CA LEU 32 0.643 9.812 7.522 1.00 0.00 C +ATOM 287 CB LEU 32 -0.697 10.218 8.192 1.00 0.00 C +ATOM 288 CG LEU 32 -0.938 11.512 9.006 1.00 0.00 C +ATOM 289 CD1 LEU 32 -1.366 12.695 8.123 1.00 0.00 C +ATOM 290 CD2 LEU 32 -2.019 11.235 10.038 1.00 0.00 C +ATOM 291 C LEU 32 1.647 9.304 8.576 1.00 0.00 C +ATOM 292 O LEU 32 2.525 10.068 8.993 1.00 0.00 O +ATOM 293 N HIS 33 1.529 8.025 8.976 1.00 0.00 N +ATOM 294 H HIS 33 0.799 7.460 8.625 1.00 0.00 H +ATOM 295 CA HIS 33 2.442 7.419 9.966 1.00 0.00 C +ATOM 296 CB HIS 33 1.932 6.049 10.459 1.00 0.00 C +ATOM 297 CG HIS 33 0.663 6.114 11.261 1.00 0.00 C +ATOM 298 CD2 HIS 33 -0.558 5.565 11.043 1.00 0.00 C +ATOM 299 ND1 HIS 33 0.567 6.789 12.460 1.00 0.00 N +ATOM 300 HD1 HIS 33 1.289 7.292 12.891 1.00 0.00 H +ATOM 301 CE1 HIS 33 -0.654 6.656 12.945 1.00 0.00 C +ATOM 302 NE2 HIS 33 -1.356 5.918 12.105 1.00 0.00 N +ATOM 303 HE2 HIS 33 -2.295 5.663 12.219 1.00 0.00 H +ATOM 304 C HIS 33 3.882 7.346 9.378 1.00 0.00 C +ATOM 305 O HIS 33 4.818 7.762 10.070 1.00 0.00 O +ATOM 306 N PRO 34 4.085 6.847 8.107 1.00 0.00 N +ATOM 307 CD PRO 34 3.266 5.927 7.291 1.00 0.00 C +ATOM 308 CA PRO 34 5.451 6.817 7.555 1.00 0.00 C +ATOM 309 CB PRO 34 5.281 6.050 6.247 1.00 0.00 C +ATOM 310 CG PRO 34 4.300 5.055 6.610 1.00 0.00 C +ATOM 311 C PRO 34 5.970 8.246 7.312 1.00 0.00 C +ATOM 312 O PRO 34 7.167 8.495 7.441 1.00 0.00 O +ATOM 313 N PHE 35 5.047 9.158 6.960 1.00 0.00 N +ATOM 314 H PHE 35 4.112 8.871 6.861 1.00 0.00 H +ATOM 315 CA PHE 35 5.318 10.591 6.698 1.00 0.00 C +ATOM 316 CB PHE 35 4.000 11.320 6.331 1.00 0.00 C +ATOM 317 CG PHE 35 3.930 11.853 4.909 1.00 0.00 C +ATOM 318 CD1 PHE 35 4.061 13.237 4.660 1.00 0.00 C +ATOM 319 CD2 PHE 35 3.665 10.993 3.816 1.00 0.00 C +ATOM 320 CE1 PHE 35 3.927 13.760 3.349 1.00 0.00 C +ATOM 321 CE2 PHE 35 3.530 11.504 2.502 1.00 0.00 C +ATOM 322 CZ PHE 35 3.662 12.888 2.268 1.00 0.00 C +ATOM 323 C PHE 35 5.941 11.273 7.930 1.00 0.00 C +ATOM 324 O PHE 35 6.948 11.972 7.797 1.00 0.00 O +ATOM 325 N ASN 36 5.365 11.019 9.117 1.00 0.00 N +ATOM 326 H ASN 36 4.579 10.430 9.159 1.00 0.00 H +ATOM 327 CA ASN 36 5.841 11.572 10.401 1.00 0.00 C +ATOM 328 CB ASN 36 4.809 11.350 11.518 1.00 0.00 C +ATOM 329 CG ASN 36 3.624 12.308 11.431 1.00 0.00 C +ATOM 330 OD1 ASN 36 3.728 13.485 11.789 1.00 0.00 O +ATOM 331 ND2 ASN 36 2.482 11.795 10.991 1.00 0.00 N +ATOM 332 HD21 ASN 36 1.714 12.398 10.911 1.00 0.00 H +ATOM 333 HD22 ASN 36 2.438 10.841 10.776 1.00 0.00 H +ATOM 334 C ASN 36 7.204 10.995 10.821 1.00 0.00 C +ATOM 335 O ASN 36 8.076 11.743 11.279 1.00 0.00 O +ATOM 336 N THR 37 7.390 9.683 10.598 1.00 0.00 N +ATOM 337 H THR 37 6.652 9.162 10.196 1.00 0.00 H +ATOM 338 CA THR 37 8.635 8.956 10.930 1.00 0.00 C +ATOM 339 CB THR 37 8.443 7.406 10.806 1.00 0.00 C +ATOM 340 OG1 THR 37 7.105 7.063 11.186 1.00 0.00 O +ATOM 341 HG1 THR 37 6.984 6.113 11.111 1.00 0.00 H +ATOM 342 CG2 THR 37 9.408 6.650 11.737 1.00 0.00 C +ATOM 343 C THR 37 9.798 9.441 10.026 1.00 0.00 C +ATOM 344 O THR 37 10.910 9.657 10.519 1.00 0.00 O +ATOM 345 N PHE 38 9.518 9.605 8.723 1.00 0.00 N +ATOM 346 H PHE 38 8.614 9.409 8.399 1.00 0.00 H +ATOM 347 CA PHE 38 10.482 10.081 7.710 1.00 0.00 C +ATOM 348 CB PHE 38 9.982 9.755 6.283 1.00 0.00 C +ATOM 349 CG PHE 38 10.393 8.380 5.768 1.00 0.00 C +ATOM 350 CD1 PHE 38 11.535 8.236 4.946 1.00 0.00 C +ATOM 351 CD2 PHE 38 9.638 7.224 6.082 1.00 0.00 C +ATOM 352 CE1 PHE 38 11.922 6.967 4.446 1.00 0.00 C +ATOM 353 CE2 PHE 38 10.014 5.947 5.589 1.00 0.00 C +ATOM 354 CZ PHE 38 11.160 5.819 4.769 1.00 0.00 C +ATOM 355 C PHE 38 10.870 11.567 7.826 1.00 0.00 C +ATOM 356 O PHE 38 12.034 11.919 7.599 1.00 0.00 O +ATOM 357 N ARG 39 9.893 12.417 8.180 1.00 0.00 N +ATOM 358 H ARG 39 8.985 12.071 8.336 1.00 0.00 H +ATOM 359 CA ARG 39 10.072 13.875 8.361 1.00 0.00 C +ATOM 360 CB ARG 39 8.720 14.590 8.470 1.00 0.00 C +ATOM 361 CG ARG 39 8.044 14.858 7.133 1.00 0.00 C +ATOM 362 CD ARG 39 6.716 15.576 7.318 1.00 0.00 C +ATOM 363 NE ARG 39 6.053 15.848 6.041 1.00 0.00 N +ATOM 364 HE ARG 39 6.493 15.546 5.219 1.00 0.00 H +ATOM 365 CZ ARG 39 4.887 16.480 5.900 1.00 0.00 C +ATOM 366 NH1 ARG 39 4.387 16.666 4.686 1.00 0.00 N +ATOM 367 HH11 ARG 39 4.884 16.334 3.884 1.00 0.00 H +ATOM 368 HH12 ARG 39 3.514 17.139 4.572 1.00 0.00 H +ATOM 369 NH2 ARG 39 4.214 16.927 6.956 1.00 0.00 N +ATOM 370 HH21 ARG 39 4.581 16.793 7.877 1.00 0.00 H +ATOM 371 HH22 ARG 39 3.341 17.399 6.829 1.00 0.00 H +ATOM 372 C ARG 39 10.949 14.219 9.576 1.00 0.00 C +ATOM 373 O ARG 39 11.716 15.187 9.533 1.00 0.00 O +ATOM 374 N LYS 40 10.819 13.419 10.645 1.00 0.00 N +ATOM 375 H LYS 40 10.158 12.682 10.624 1.00 0.00 H +ATOM 376 CA LYS 40 11.580 13.569 11.904 1.00 0.00 C +ATOM 377 CB LYS 40 11.074 12.588 12.969 1.00 0.00 C +ATOM 378 CG LYS 40 9.778 13.010 13.648 1.00 0.00 C +ATOM 379 CD LYS 40 9.341 11.987 14.691 1.00 0.00 C +ATOM 380 CE LYS 40 8.042 12.391 15.385 1.00 0.00 C +ATOM 381 NZ LYS 40 8.185 13.585 16.271 1.00 0.00 N +ATOM 382 HZ1 LYS 40 8.885 13.384 17.014 1.00 0.00 H +ATOM 383 HZ2 LYS 40 8.501 14.399 15.707 1.00 0.00 H +ATOM 384 HZ3 LYS 40 7.267 13.803 16.710 1.00 0.00 H +ATOM 385 C LYS 40 13.105 13.420 11.744 1.00 0.00 C +ATOM 386 O LYS 40 13.863 14.116 12.429 1.00 0.00 O +ATOM 387 N GLU 41 13.534 12.526 10.839 1.00 0.00 N +ATOM 388 H GLU 41 12.884 12.009 10.314 1.00 0.00 H +ATOM 389 CA GLU 41 14.959 12.249 10.560 1.00 0.00 C +ATOM 390 CB GLU 41 15.131 10.801 10.036 1.00 0.00 C +ATOM 391 CG GLU 41 16.432 10.061 10.454 1.00 0.00 C +ATOM 392 CD GLU 41 16.317 9.302 11.777 1.00 0.00 C +ATOM 393 OE1 GLU 41 16.080 8.077 11.742 1.00 0.00 O +ATOM 394 OE2 GLU 41 16.470 9.935 12.844 1.00 0.00 O +ATOM 395 C GLU 41 15.614 13.272 9.600 1.00 0.00 C +ATOM 396 O GLU 41 16.610 13.903 9.969 1.00 0.00 O +ATOM 397 N GLY 42 15.056 13.423 8.393 1.00 0.00 N +ATOM 398 H GLY 42 14.267 12.902 8.130 1.00 0.00 H +ATOM 399 CA GLY 42 15.597 14.365 7.419 1.00 0.00 C +ATOM 400 C GLY 42 15.320 14.030 5.966 1.00 0.00 C +ATOM 401 O GLY 42 15.743 14.777 5.079 1.00 0.00 O +ATOM 402 N PHE 43 14.581 12.940 5.728 1.00 0.00 N +ATOM 403 H PHE 43 14.247 12.420 6.489 1.00 0.00 H +ATOM 404 CA PHE 43 14.235 12.469 4.375 1.00 0.00 C +ATOM 405 CB PHE 43 13.971 10.940 4.384 1.00 0.00 C +ATOM 406 CG PHE 43 15.063 10.104 5.058 1.00 0.00 C +ATOM 407 CD1 PHE 43 16.242 9.744 4.364 1.00 0.00 C +ATOM 408 CD2 PHE 43 14.900 9.650 6.388 1.00 0.00 C +ATOM 409 CE1 PHE 43 17.244 8.945 4.981 1.00 0.00 C +ATOM 410 CE2 PHE 43 15.893 8.850 7.018 1.00 0.00 C +ATOM 411 CZ PHE 43 17.068 8.497 6.312 1.00 0.00 C +ATOM 412 C PHE 43 13.033 13.221 3.772 1.00 0.00 C +ATOM 413 O PHE 43 12.057 13.502 4.480 1.00 0.00 O +ATOM 414 N GLU 44 13.128 13.548 2.474 1.00 0.00 N +ATOM 415 H GLU 44 13.930 13.295 1.964 1.00 0.00 H +ATOM 416 CA GLU 44 12.090 14.281 1.715 1.00 0.00 C +ATOM 417 CB GLU 44 12.712 15.010 0.516 1.00 0.00 C +ATOM 418 CG GLU 44 13.618 16.184 0.881 1.00 0.00 C +ATOM 419 CD GLU 44 14.206 16.871 -0.338 1.00 0.00 C +ATOM 420 OE1 GLU 44 13.576 17.819 -0.851 1.00 0.00 O +ATOM 421 OE2 GLU 44 15.301 16.464 -0.781 1.00 0.00 O +ATOM 422 C GLU 44 10.933 13.382 1.244 1.00 0.00 C +ATOM 423 O GLU 44 11.162 12.232 0.856 1.00 0.00 O +ATOM 424 N VAL 45 9.708 13.926 1.285 1.00 0.00 N +ATOM 425 H VAL 45 9.588 14.855 1.583 1.00 0.00 H +ATOM 426 CA VAL 45 8.466 13.220 0.903 1.00 0.00 C +ATOM 427 CG1 VAL 45 7.783 12.144 3.094 1.00 0.00 C +ATOM 428 CG2 VAL 45 7.334 14.589 2.779 1.00 0.00 C +ATOM 429 C VAL 45 7.804 13.699 -0.411 1.00 0.00 C +ATOM 430 O VAL 45 7.816 14.898 -0.717 1.00 0.00 O +ATOM 431 CB VAL 45 7.413 13.213 2.078 1.00 0.00 C +ATOM 432 N ASP 46 7.256 12.738 -1.172 1.00 0.00 N +ATOM 433 H ASP 46 7.290 11.801 -0.879 1.00 0.00 H +ATOM 434 CA ASP 46 6.575 12.960 -2.465 1.00 0.00 C +ATOM 435 CB ASP 46 7.413 12.388 -3.626 1.00 0.00 C +ATOM 436 CG ASP 46 8.743 13.111 -3.814 1.00 0.00 C +ATOM 437 OD1 ASP 46 8.788 14.094 -4.587 1.00 0.00 O +ATOM 438 OD2 ASP 46 9.748 12.688 -3.202 1.00 0.00 O +ATOM 439 C ASP 46 5.178 12.313 -2.470 1.00 0.00 C +ATOM 440 O ASP 46 4.992 11.253 -1.858 1.00 0.00 O +ATOM 441 N PHE 47 4.211 12.961 -3.140 1.00 0.00 N +ATOM 442 H PHE 47 4.405 13.810 -3.593 1.00 0.00 H +ATOM 443 CA PHE 47 2.818 12.470 -3.249 1.00 0.00 C +ATOM 444 CB PHE 47 1.791 13.590 -2.932 1.00 0.00 C +ATOM 445 CG PHE 47 1.962 14.279 -1.581 1.00 0.00 C +ATOM 446 CD1 PHE 47 2.948 15.279 -1.387 1.00 0.00 C +ATOM 447 CD2 PHE 47 1.065 14.006 -0.523 1.00 0.00 C +ATOM 448 CE1 PHE 47 3.035 15.999 -0.163 1.00 0.00 C +ATOM 449 CE2 PHE 47 1.138 14.717 0.706 1.00 0.00 C +ATOM 450 CZ PHE 47 2.126 15.718 0.885 1.00 0.00 C +ATOM 451 C PHE 47 2.528 11.972 -4.677 1.00 0.00 C +ATOM 452 O PHE 47 2.799 12.685 -5.655 1.00 0.00 O +ATOM 453 N VAL 48 2.031 10.731 -4.784 1.00 0.00 N +ATOM 454 H VAL 48 1.891 10.183 -3.980 1.00 0.00 H +ATOM 455 CA VAL 48 1.662 10.087 -6.063 1.00 0.00 C +ATOM 456 CB VAL 48 2.685 8.955 -6.491 1.00 0.00 C +ATOM 457 CG1 VAL 48 2.202 8.181 -7.718 1.00 0.00 C +ATOM 458 CG2 VAL 48 4.059 9.555 -6.774 1.00 0.00 C +ATOM 459 C VAL 48 0.236 9.514 -5.955 1.00 0.00 C +ATOM 460 O VAL 48 -0.173 9.045 -4.885 1.00 0.00 O +ATOM 461 N SER 49 -0.515 9.623 -7.059 1.00 0.00 N +ATOM 462 H SER 49 -0.158 10.068 -7.859 1.00 0.00 H +ATOM 463 CA SER 49 -1.891 9.117 -7.196 1.00 0.00 C +ATOM 464 CB SER 49 -2.882 10.288 -7.286 1.00 0.00 C +ATOM 465 OG SER 49 -4.218 9.829 -7.420 1.00 0.00 O +ATOM 466 HG SER 49 -4.483 9.332 -6.642 1.00 0.00 H +ATOM 467 C SER 49 -1.969 8.279 -8.482 1.00 0.00 C +ATOM 468 O SER 49 -0.987 8.207 -9.232 1.00 0.00 O +ATOM 469 N GLU 50 -3.132 7.653 -8.722 1.00 0.00 N +ATOM 470 H GLU 50 -3.870 7.709 -8.075 1.00 0.00 H +ATOM 471 CA GLU 50 -3.395 6.855 -9.930 1.00 0.00 C +ATOM 472 CB GLU 50 -4.227 5.607 -9.603 1.00 0.00 C +ATOM 473 CG GLU 50 -4.129 4.461 -10.624 1.00 0.00 C +ATOM 474 CD GLU 50 -5.116 3.343 -10.347 1.00 0.00 C +ATOM 475 OE1 GLU 50 -4.742 2.378 -9.649 1.00 0.00 O +ATOM 476 OE2 GLU 50 -6.265 3.426 -10.831 1.00 0.00 O +ATOM 477 C GLU 50 -4.152 7.802 -10.884 1.00 0.00 C +ATOM 478 O GLU 50 -4.986 8.595 -10.428 1.00 0.00 O +ATOM 479 N THR 51 -3.829 7.720 -12.187 1.00 0.00 N +ATOM 480 H THR 51 -3.177 7.051 -12.475 1.00 0.00 H +ATOM 481 CA THR 51 -4.379 8.537 -13.308 1.00 0.00 C +ATOM 482 CB THR 51 -5.920 8.311 -13.577 1.00 0.00 C +ATOM 483 OG1 THR 51 -6.680 8.635 -12.406 1.00 0.00 O +ATOM 484 HG1 THR 51 -6.571 9.563 -12.184 1.00 0.00 H +ATOM 485 CG2 THR 51 -6.195 6.867 -13.981 1.00 0.00 C +ATOM 486 C THR 51 -4.057 10.047 -13.253 1.00 0.00 C +ATOM 487 O THR 51 -3.777 10.660 -14.291 1.00 0.00 O +ATOM 488 N GLY 52 -4.073 10.621 -12.042 1.00 0.00 N +ATOM 489 H GLY 52 -4.285 10.128 -11.230 1.00 0.00 H +ATOM 490 CA GLY 52 -3.786 12.038 -11.832 1.00 0.00 C +ATOM 491 C GLY 52 -5.034 12.912 -11.905 1.00 0.00 C +ATOM 492 O GLY 52 -5.126 13.778 -12.784 1.00 0.00 O +ATOM 493 N LYS 53 -5.983 12.674 -10.991 1.00 0.00 N +ATOM 494 H LYS 53 -5.831 11.967 -10.329 1.00 0.00 H +ATOM 495 CA LYS 53 -7.258 13.412 -10.911 1.00 0.00 C +ATOM 496 CB LYS 53 -8.465 12.452 -11.075 1.00 0.00 C +ATOM 497 CG LYS 53 -8.442 11.138 -10.266 1.00 0.00 C +ATOM 498 CD LYS 53 -9.677 10.300 -10.554 1.00 0.00 C +ATOM 499 CE LYS 53 -9.651 8.992 -9.783 1.00 0.00 C +ATOM 500 NZ LYS 53 -10.857 8.162 -10.057 1.00 0.00 N +ATOM 501 HZ1 LYS 53 -10.800 7.278 -9.512 1.00 0.00 H +ATOM 502 HZ2 LYS 53 -11.710 8.687 -9.779 1.00 0.00 H +ATOM 503 HZ3 LYS 53 -10.902 7.941 -11.073 1.00 0.00 H +ATOM 504 C LYS 53 -7.401 14.285 -9.644 1.00 0.00 C +ATOM 505 O LYS 53 -8.355 15.067 -9.526 1.00 0.00 O +ATOM 506 N PHE 54 -6.408 14.180 -8.745 1.00 0.00 N +ATOM 507 H PHE 54 -5.654 13.579 -8.932 1.00 0.00 H +ATOM 508 CA PHE 54 -6.297 14.891 -7.443 1.00 0.00 C +ATOM 509 CB PHE 54 -5.534 16.254 -7.572 1.00 0.00 C +ATOM 510 CG PHE 54 -6.238 17.329 -8.421 1.00 0.00 C +ATOM 511 CD1 PHE 54 -7.137 18.248 -7.825 1.00 0.00 C +ATOM 512 CD2 PHE 54 -5.968 17.456 -9.803 1.00 0.00 C +ATOM 513 CE1 PHE 54 -7.756 19.274 -8.590 1.00 0.00 C +ATOM 514 CE2 PHE 54 -6.579 18.478 -10.583 1.00 0.00 C +ATOM 515 CZ PHE 54 -7.476 19.389 -9.973 1.00 0.00 C +ATOM 516 C PHE 54 -7.538 15.012 -6.523 1.00 0.00 C +ATOM 517 O PHE 54 -8.555 15.600 -6.912 1.00 0.00 O +ATOM 518 N GLY 55 -7.432 14.430 -5.320 1.00 0.00 N +ATOM 519 H GLY 55 -6.610 13.965 -5.056 1.00 0.00 H +ATOM 520 CA GLY 55 -8.503 14.448 -4.325 1.00 0.00 C +ATOM 521 C GLY 55 -9.515 13.320 -4.470 1.00 0.00 C +ATOM 522 O GLY 55 -9.982 13.064 -5.587 1.00 0.00 O +ATOM 523 N TRP 56 -9.850 12.656 -3.354 1.00 0.00 N +ATOM 524 H TRP 56 -9.458 12.943 -2.505 1.00 0.00 H +ATOM 525 CA TRP 56 -10.804 11.532 -3.338 1.00 0.00 C +ATOM 526 CB TRP 56 -10.053 10.169 -3.424 1.00 0.00 C +ATOM 527 CG TRP 56 -9.239 9.612 -2.196 1.00 0.00 C +ATOM 528 CD2 TRP 56 -8.349 10.315 -1.285 1.00 0.00 C +ATOM 529 CE2 TRP 56 -7.763 9.334 -0.439 1.00 0.00 C +ATOM 530 CE3 TRP 56 -7.985 11.668 -1.105 1.00 0.00 C +ATOM 531 CD1 TRP 56 -9.153 8.292 -1.844 1.00 0.00 C +ATOM 532 NE1 TRP 56 -8.277 8.121 -0.804 1.00 0.00 N +ATOM 533 HE1 TRP 56 -8.085 7.279 -0.351 1.00 0.00 H +ATOM 534 CZ2 TRP 56 -6.829 9.658 0.571 1.00 0.00 C +ATOM 535 CZ3 TRP 56 -7.054 11.990 -0.094 1.00 0.00 C +ATOM 536 CH2 TRP 56 -6.490 10.986 0.726 1.00 0.00 C +ATOM 537 C TRP 56 -11.821 11.527 -2.180 1.00 0.00 C +ATOM 538 O TRP 56 -13.031 11.462 -2.426 1.00 0.00 O +ATOM 539 N ASP 57 -11.318 11.599 -0.937 1.00 0.00 N +ATOM 540 H ASP 57 -10.354 11.677 -0.795 1.00 0.00 H +ATOM 541 CA ASP 57 -12.138 11.573 0.291 1.00 0.00 C +ATOM 542 CB ASP 57 -11.988 10.213 0.996 1.00 0.00 C +ATOM 543 CG ASP 57 -12.622 9.067 0.219 1.00 0.00 C +ATOM 544 OD1 ASP 57 -13.812 8.763 0.456 1.00 0.00 O +ATOM 545 OD2 ASP 57 -11.925 8.455 -0.617 1.00 0.00 O +ATOM 546 C ASP 57 -11.823 12.688 1.303 1.00 0.00 C +ATOM 547 O ASP 57 -10.984 13.556 1.042 1.00 0.00 O +ATOM 548 N GLU 58 -12.468 12.603 2.482 1.00 0.00 N +ATOM 549 H GLU 58 -13.097 11.863 2.632 1.00 0.00 H +ATOM 550 CA GLU 58 -12.359 13.520 3.648 1.00 0.00 C +ATOM 551 CB GLU 58 -11.207 13.115 4.608 1.00 0.00 C +ATOM 552 CG GLU 58 -9.801 12.875 4.020 1.00 0.00 C +ATOM 553 CD GLU 58 -8.796 12.386 5.055 1.00 0.00 C +ATOM 554 OE1 GLU 58 -7.771 13.065 5.253 1.00 0.00 O +ATOM 555 OE2 GLU 58 -9.018 11.319 5.668 1.00 0.00 O +ATOM 556 C GLU 58 -12.442 15.052 3.453 1.00 0.00 C +ATOM 557 O GLU 58 -13.434 15.665 3.866 1.00 0.00 O +ATOM 558 N HIS 59 -11.412 15.648 2.835 1.00 0.00 N +ATOM 559 H HIS 59 -10.643 15.117 2.536 1.00 0.00 H +ATOM 560 CA HIS 59 -11.347 17.097 2.562 1.00 0.00 C +ATOM 561 CB HIS 59 -9.894 17.597 2.726 1.00 0.00 C +ATOM 562 CG HIS 59 -9.772 19.066 3.026 1.00 0.00 C +ATOM 563 CD2 HIS 59 -9.258 20.086 2.297 1.00 0.00 C +ATOM 564 ND1 HIS 59 -10.191 19.624 4.216 1.00 0.00 N +ATOM 565 HD1 HIS 59 -10.609 19.139 4.958 1.00 0.00 H +ATOM 566 CE1 HIS 59 -9.942 20.921 4.207 1.00 0.00 C +ATOM 567 NE2 HIS 59 -9.376 21.227 3.054 1.00 0.00 N +ATOM 568 HE2 HIS 59 -9.088 22.123 2.782 1.00 0.00 H +ATOM 569 C HIS 59 -11.864 17.330 1.124 1.00 0.00 C +ATOM 570 O HIS 59 -12.141 18.470 0.725 1.00 0.00 O +ATOM 571 N SER 60 -12.014 16.219 0.389 1.00 0.00 N +ATOM 572 H SER 60 -11.796 15.343 0.771 1.00 0.00 H +ATOM 573 CA SER 60 -12.500 16.178 -0.999 1.00 0.00 C +ATOM 574 CB SER 60 -11.461 15.483 -1.895 1.00 0.00 C +ATOM 575 OG SER 60 -10.978 14.290 -1.315 1.00 0.00 O +ATOM 576 HG SER 60 -11.712 13.691 -1.189 1.00 0.00 H +ATOM 577 C SER 60 -13.863 15.455 -1.066 1.00 0.00 C +ATOM 578 O SER 60 -14.475 15.361 -2.141 1.00 0.00 O +ATOM 579 N LEU 61 -14.342 15.002 0.104 1.00 0.00 N +ATOM 580 H LEU 61 -13.831 15.138 0.932 1.00 0.00 H +ATOM 581 CA LEU 61 -15.625 14.287 0.272 1.00 0.00 C +ATOM 582 CB LEU 61 -15.464 13.187 1.356 1.00 0.00 C +ATOM 583 CG LEU 61 -16.317 11.901 1.478 1.00 0.00 C +ATOM 584 CD1 LEU 61 -15.483 10.832 2.159 1.00 0.00 C +ATOM 585 CD2 LEU 61 -17.631 12.118 2.249 1.00 0.00 C +ATOM 586 C LEU 61 -16.747 15.290 0.652 1.00 0.00 C +ATOM 587 O LEU 61 -17.918 14.902 0.785 1.00 0.00 O +ATOM 588 N ALA 62 -16.377 16.575 0.758 1.00 0.00 N +ATOM 589 H ALA 62 -15.444 16.833 0.590 1.00 0.00 H +ATOM 590 CA ALA 62 -17.283 17.685 1.117 1.00 0.00 C +ATOM 591 CB ALA 62 -16.470 18.843 1.706 1.00 0.00 C +ATOM 592 C ALA 62 -18.156 18.176 -0.060 1.00 0.00 C +ATOM 593 O ALA 62 -18.894 19.164 0.073 1.00 0.00 O +ATOM 594 N LYS 63 -18.095 17.444 -1.181 1.00 0.00 N +ATOM 595 H LYS 63 -17.520 16.650 -1.226 1.00 0.00 H +ATOM 596 CA LYS 63 -18.852 17.745 -2.414 1.00 0.00 C +ATOM 597 CB LYS 63 -18.008 17.430 -3.672 1.00 0.00 C +ATOM 598 CG LYS 63 -17.288 16.064 -3.716 1.00 0.00 C +ATOM 599 CD LYS 63 -16.499 15.894 -5.010 1.00 0.00 C +ATOM 600 CE LYS 63 -15.779 14.549 -5.075 1.00 0.00 C +ATOM 601 NZ LYS 63 -16.703 13.383 -5.207 1.00 0.00 N +ATOM 602 HZ1 LYS 63 -17.343 13.353 -4.388 1.00 0.00 H +ATOM 603 HZ2 LYS 63 -17.260 13.479 -6.080 1.00 0.00 H +ATOM 604 HZ3 LYS 63 -16.148 12.504 -5.245 1.00 0.00 H +ATOM 605 C LYS 63 -20.241 17.069 -2.485 1.00 0.00 C +ATOM 606 O LYS 63 -21.160 17.603 -3.120 1.00 0.00 O +ATOM 607 N ASP 64 -20.371 15.912 -1.819 1.00 0.00 N +ATOM 608 H ASP 64 -19.610 15.536 -1.324 1.00 0.00 H +ATOM 609 CA ASP 64 -21.617 15.122 -1.766 1.00 0.00 C +ATOM 610 CB ASP 64 -21.336 13.641 -2.086 1.00 0.00 C +ATOM 611 CG ASP 64 -20.858 13.422 -3.519 1.00 0.00 C +ATOM 612 OD1 ASP 64 -19.630 13.454 -3.753 1.00 0.00 O +ATOM 613 OD2 ASP 64 -21.710 13.201 -4.408 1.00 0.00 O +ATOM 614 C ASP 64 -22.304 15.236 -0.395 1.00 0.00 C +ATOM 615 O ASP 64 -21.623 15.316 0.635 1.00 0.00 O +ATOM 616 N PHE 65 -23.645 15.258 -0.405 1.00 0.00 N +ATOM 617 H PHE 65 -24.137 15.200 -1.253 1.00 0.00 H +ATOM 618 CA PHE 65 -24.480 15.366 0.807 1.00 0.00 C +ATOM 619 CB PHE 65 -25.434 16.586 0.707 1.00 0.00 C +ATOM 620 CG PHE 65 -24.733 17.943 0.642 1.00 0.00 C +ATOM 621 CD1 PHE 65 -24.451 18.671 1.823 1.00 0.00 C +ATOM 622 CD2 PHE 65 -24.387 18.521 -0.604 1.00 0.00 C +ATOM 623 CE1 PHE 65 -23.834 19.952 1.769 1.00 0.00 C +ATOM 624 CE2 PHE 65 -23.770 19.801 -0.675 1.00 0.00 C +ATOM 625 CZ PHE 65 -23.493 20.518 0.516 1.00 0.00 C +ATOM 626 C PHE 65 -25.300 14.090 1.050 1.00 0.00 C +ATOM 627 O PHE 65 -25.677 13.406 0.093 1.00 0.00 O +ATOM 628 N LEU 66 -25.582 13.803 2.335 1.00 0.00 N +ATOM 629 H LEU 66 -25.261 14.404 3.043 1.00 0.00 H +ATOM 630 CA LEU 66 -26.357 12.634 2.842 1.00 0.00 C +ATOM 631 CB LEU 66 -27.856 12.706 2.444 1.00 0.00 C +ATOM 632 CG LEU 66 -28.780 13.804 3.004 1.00 0.00 C +ATOM 633 CD1 LEU 66 -29.614 14.386 1.872 1.00 0.00 C +ATOM 634 CD2 LEU 66 -29.689 13.271 4.122 1.00 0.00 C +ATOM 635 C LEU 66 -25.793 11.232 2.537 1.00 0.00 C +ATOM 636 O LEU 66 -25.612 10.430 3.461 1.00 0.00 O +ATOM 637 N ASN 67 -25.505 10.961 1.250 1.00 0.00 N +ATOM 638 H ASN 67 -25.670 11.635 0.564 1.00 0.00 H +ATOM 639 CA ASN 67 -24.958 9.687 0.705 1.00 0.00 C +ATOM 640 CB ASN 67 -23.523 9.402 1.210 1.00 0.00 C +ATOM 641 CG ASN 67 -22.513 10.444 0.743 1.00 0.00 C +ATOM 642 OD1 ASN 67 -22.276 11.445 1.422 1.00 0.00 O +ATOM 643 ND2 ASN 67 -21.901 10.202 -0.414 1.00 0.00 N +ATOM 644 HD21 ASN 67 -21.249 10.863 -0.728 1.00 0.00 H +ATOM 645 HD22 ASN 67 -22.118 9.384 -0.909 1.00 0.00 H +ATOM 646 C ASN 67 -25.836 8.431 0.860 1.00 0.00 C +ATOM 647 O ASN 67 -26.053 7.709 -0.120 1.00 0.00 O +ATOM 648 N GLY 68 -26.327 8.186 2.079 1.00 0.00 N +ATOM 649 H GLY 68 -26.132 8.765 2.841 1.00 0.00 H +ATOM 650 CA GLY 68 -27.173 7.031 2.352 1.00 0.00 C +ATOM 651 C GLY 68 -27.472 6.845 3.830 1.00 0.00 C +ATOM 652 O GLY 68 -26.974 7.610 4.664 1.00 0.00 O +ATOM 653 N GLN 69 -28.288 5.828 4.139 1.00 0.00 N +ATOM 654 H GLN 69 -28.644 5.270 3.414 1.00 0.00 H +ATOM 655 CA GLN 69 -28.698 5.480 5.510 1.00 0.00 C +ATOM 656 CB GLN 69 -30.235 5.416 5.602 1.00 0.00 C +ATOM 657 CG GLN 69 -30.832 5.938 6.914 1.00 0.00 C +ATOM 658 CD GLN 69 -32.346 5.848 6.942 1.00 0.00 C +ATOM 659 OE1 GLN 69 -33.042 6.787 6.555 1.00 0.00 O +ATOM 660 NE2 GLN 69 -32.864 4.714 7.402 1.00 0.00 N +ATOM 661 HE21 GLN 69 -32.266 3.996 7.698 1.00 0.00 H +ATOM 662 HE22 GLN 69 -33.841 4.641 7.426 1.00 0.00 H +ATOM 663 C GLN 69 -28.080 4.122 5.904 1.00 0.00 C +ATOM 664 O GLN 69 -27.840 3.869 7.091 1.00 0.00 O +ATOM 665 N ASP 70 -27.823 3.277 4.895 1.00 0.00 N +ATOM 666 H ASP 70 -28.027 3.536 3.969 1.00 0.00 H +ATOM 667 CA ASP 70 -27.234 1.933 5.059 1.00 0.00 C +ATOM 668 CB ASP 70 -27.980 0.902 4.170 1.00 0.00 C +ATOM 669 CG ASP 70 -28.161 1.364 2.717 1.00 0.00 C +ATOM 670 OD1 ASP 70 -29.193 2.002 2.415 1.00 0.00 O +ATOM 671 OD2 ASP 70 -27.276 1.075 1.882 1.00 0.00 O +ATOM 672 C ASP 70 -25.703 1.917 4.810 1.00 0.00 C +ATOM 673 O ASP 70 -25.090 0.847 4.694 1.00 0.00 O +ATOM 674 N GLU 71 -25.105 3.116 4.798 1.00 0.00 N +ATOM 675 H GLU 71 -25.645 3.923 4.951 1.00 0.00 H +ATOM 676 CA GLU 71 -23.662 3.345 4.572 1.00 0.00 C +ATOM 677 CB GLU 71 -23.381 4.831 4.245 1.00 0.00 C +ATOM 678 CG GLU 71 -24.010 5.889 5.178 1.00 0.00 C +ATOM 679 CD GLU 71 -23.640 7.307 4.787 1.00 0.00 C +ATOM 680 OE1 GLU 71 -24.372 7.913 3.976 1.00 0.00 O +ATOM 681 OE2 GLU 71 -22.617 7.816 5.290 1.00 0.00 O +ATOM 682 C GLU 71 -22.705 2.834 5.672 1.00 0.00 C +ATOM 683 O GLU 71 -21.617 2.338 5.357 1.00 0.00 O +ATOM 684 N THR 72 -23.137 2.933 6.939 1.00 0.00 N +ATOM 685 H THR 72 -24.033 3.311 7.095 1.00 0.00 H +ATOM 686 CA THR 72 -22.359 2.509 8.126 1.00 0.00 C +ATOM 687 CB THR 72 -23.096 2.861 9.454 1.00 0.00 C +ATOM 688 OG1 THR 72 -24.445 2.379 9.403 1.00 0.00 O +ATOM 689 HG1 THR 72 -24.935 2.820 8.704 1.00 0.00 H +ATOM 690 CG2 THR 72 -23.100 4.368 9.689 1.00 0.00 C +ATOM 691 C THR 72 -21.968 1.014 8.128 1.00 0.00 C +ATOM 692 O THR 72 -20.815 0.680 8.432 1.00 0.00 O +ATOM 693 N ASP 73 -22.924 0.139 7.777 1.00 0.00 N +ATOM 694 H ASP 73 -23.825 0.462 7.555 1.00 0.00 H +ATOM 695 CA ASP 73 -22.721 -1.323 7.695 1.00 0.00 C +ATOM 696 CG ASP 73 -25.104 -1.500 6.729 1.00 0.00 C +ATOM 697 OD1 ASP 73 -25.828 -0.556 7.116 1.00 0.00 O +ATOM 698 OD2 ASP 73 -25.200 -2.002 5.590 1.00 0.00 O +ATOM 699 C ASP 73 -21.817 -1.768 6.522 1.00 0.00 C +ATOM 700 O ASP 73 -20.969 -2.652 6.694 1.00 0.00 O +ATOM 701 CB ASP 73 -24.069 -2.084 7.699 1.00 0.00 C +ATOM 702 N PHE 74 -22.020 -1.146 5.349 1.00 0.00 N +ATOM 703 H PHE 74 -22.720 -0.459 5.280 1.00 0.00 H +ATOM 704 CA PHE 74 -21.252 -1.411 4.111 1.00 0.00 C +ATOM 705 CB PHE 74 -21.966 -0.808 2.876 1.00 0.00 C +ATOM 706 CG PHE 74 -23.110 -1.657 2.319 1.00 0.00 C +ATOM 707 CD1 PHE 74 -24.452 -1.372 2.658 1.00 0.00 C +ATOM 708 CD2 PHE 74 -22.855 -2.719 1.416 1.00 0.00 C +ATOM 709 CE1 PHE 74 -25.526 -2.128 2.111 1.00 0.00 C +ATOM 710 CE2 PHE 74 -23.918 -3.484 0.861 1.00 0.00 C +ATOM 711 CZ PHE 74 -25.257 -3.187 1.210 1.00 0.00 C +ATOM 712 C PHE 74 -19.781 -0.949 4.138 1.00 0.00 C +ATOM 713 O PHE 74 -18.909 -1.636 3.592 1.00 0.00 O +ATOM 714 N LYS 75 -19.527 0.199 4.783 1.00 0.00 N +ATOM 715 H LYS 75 -20.271 0.686 5.206 1.00 0.00 H +ATOM 716 CA LYS 75 -18.186 0.816 4.917 1.00 0.00 C +ATOM 717 CB LYS 75 -18.299 2.237 5.486 1.00 0.00 C +ATOM 718 CG LYS 75 -18.727 3.292 4.475 1.00 0.00 C +ATOM 719 CD LYS 75 -18.825 4.664 5.123 1.00 0.00 C +ATOM 720 CE LYS 75 -19.264 5.719 4.122 1.00 0.00 C +ATOM 721 NZ LYS 75 -19.364 7.068 4.745 1.00 0.00 N +ATOM 722 HZ1 LYS 75 -20.060 7.042 5.517 1.00 0.00 H +ATOM 723 HZ2 LYS 75 -18.436 7.345 5.124 1.00 0.00 H +ATOM 724 HZ3 LYS 75 -19.666 7.759 4.029 1.00 0.00 H +ATOM 725 C LYS 75 -17.160 0.014 5.739 1.00 0.00 C +ATOM 726 O LYS 75 -15.965 0.032 5.417 1.00 0.00 O +ATOM 727 N ASN 76 -17.641 -0.665 6.798 1.00 0.00 N +ATOM 728 H ASN 76 -18.603 -0.624 6.995 1.00 0.00 H +ATOM 729 CA ASN 76 -16.862 -1.507 7.751 1.00 0.00 C +ATOM 730 CB ASN 76 -16.067 -2.628 7.017 1.00 0.00 C +ATOM 731 CG ASN 76 -15.842 -3.869 7.883 1.00 0.00 C +ATOM 732 OD1 ASN 76 -16.650 -4.799 7.878 1.00 0.00 O +ATOM 733 ND2 ASN 76 -14.733 -3.888 8.617 1.00 0.00 N +ATOM 734 HD21 ASN 76 -14.118 -3.125 8.576 1.00 0.00 H +ATOM 735 HD22 ASN 76 -14.573 -4.676 9.178 1.00 0.00 H +ATOM 736 C ASN 76 -15.957 -0.662 8.690 1.00 0.00 C +ATOM 737 O ASN 76 -15.191 -1.212 9.495 1.00 0.00 O +ATOM 738 N LYS 77 -16.117 0.671 8.606 1.00 0.00 N +ATOM 739 H LYS 77 -16.771 1.037 7.969 1.00 0.00 H +ATOM 740 CA LYS 77 -15.395 1.713 9.390 1.00 0.00 C +ATOM 741 CB LYS 77 -15.936 1.824 10.832 1.00 0.00 C +ATOM 742 CG LYS 77 -17.358 2.362 10.940 1.00 0.00 C +ATOM 743 CD LYS 77 -17.812 2.439 12.394 1.00 0.00 C +ATOM 744 CE LYS 77 -19.236 2.976 12.526 1.00 0.00 C +ATOM 745 NZ LYS 77 -20.278 2.043 12.002 1.00 0.00 N +ATOM 746 HZ1 LYS 77 -21.218 2.470 12.123 1.00 0.00 H +ATOM 747 HZ2 LYS 77 -20.234 1.145 12.526 1.00 0.00 H +ATOM 748 HZ3 LYS 77 -20.106 1.863 10.992 1.00 0.00 H +ATOM 749 C LYS 77 -13.853 1.682 9.406 1.00 0.00 C +ATOM 750 O LYS 77 -13.248 0.631 9.661 1.00 0.00 O +ATOM 751 N ASP 78 -13.245 2.841 9.109 1.00 0.00 N +ATOM 752 H ASP 78 -13.779 3.636 8.893 1.00 0.00 H +ATOM 753 CA ASP 78 -11.780 3.049 9.072 1.00 0.00 C +ATOM 754 CB ASP 78 -11.232 2.939 7.618 1.00 0.00 C +ATOM 755 CG ASP 78 -12.036 3.757 6.597 1.00 0.00 C +ATOM 756 OD1 ASP 78 -11.697 4.940 6.377 1.00 0.00 O +ATOM 757 OD2 ASP 78 -12.994 3.208 6.012 1.00 0.00 O +ATOM 758 C ASP 78 -11.407 4.406 9.718 1.00 0.00 C +ATOM 759 O ASP 78 -12.281 5.075 10.282 1.00 0.00 O +ATOM 760 N SER 79 -10.123 4.791 9.631 1.00 0.00 N +ATOM 761 H SER 79 -9.473 4.211 9.176 1.00 0.00 H +ATOM 762 CA SER 79 -9.588 6.055 10.177 1.00 0.00 C +ATOM 763 CB SER 79 -8.127 5.860 10.605 1.00 0.00 C +ATOM 764 OG SER 79 -7.625 6.993 11.297 1.00 0.00 O +ATOM 765 HG SER 79 -7.622 7.764 10.723 1.00 0.00 H +ATOM 766 C SER 79 -9.696 7.171 9.117 1.00 0.00 C +ATOM 767 O SER 79 -9.325 6.952 7.957 1.00 0.00 O +ATOM 768 N ASP 80 -10.240 8.334 9.512 1.00 0.00 N +ATOM 769 H ASP 80 -10.528 8.453 10.444 1.00 0.00 H +ATOM 770 CA ASP 80 -10.445 9.496 8.618 1.00 0.00 C +ATOM 771 CB ASP 80 -11.849 9.404 7.962 1.00 0.00 C +ATOM 772 CG ASP 80 -12.056 10.396 6.817 1.00 0.00 C +ATOM 773 OD1 ASP 80 -11.801 10.032 5.649 1.00 0.00 O +ATOM 774 OD2 ASP 80 -12.499 11.534 7.089 1.00 0.00 O +ATOM 775 C ASP 80 -10.291 10.853 9.343 1.00 0.00 C +ATOM 776 O ASP 80 -10.665 10.984 10.515 1.00 0.00 O +ATOM 777 N PHE 81 -9.725 11.835 8.621 1.00 0.00 N +ATOM 778 H PHE 81 -9.408 11.652 7.709 1.00 0.00 H +ATOM 779 CA PHE 81 -9.516 13.230 9.076 1.00 0.00 C +ATOM 780 CB PHE 81 -8.078 13.474 9.654 1.00 0.00 C +ATOM 781 CG PHE 81 -6.941 12.760 8.920 1.00 0.00 C +ATOM 782 CD1 PHE 81 -6.216 13.415 7.897 1.00 0.00 C +ATOM 783 CD2 PHE 81 -6.545 11.456 9.298 1.00 0.00 C +ATOM 784 CE1 PHE 81 -5.113 12.784 7.262 1.00 0.00 C +ATOM 785 CE2 PHE 81 -5.444 10.813 8.672 1.00 0.00 C +ATOM 786 CZ PHE 81 -4.727 11.479 7.652 1.00 0.00 C +ATOM 787 C PHE 81 -9.887 14.188 7.915 1.00 0.00 C +ATOM 788 O PHE 81 -11.056 14.198 7.515 1.00 0.00 O +ATOM 789 N ASN 82 -8.941 15.007 7.416 1.00 0.00 N +ATOM 790 H ASN 82 -8.038 15.029 7.788 1.00 0.00 H +ATOM 791 CA ASN 82 -9.152 15.948 6.286 1.00 0.00 C +ATOM 792 CB ASN 82 -9.737 17.306 6.742 1.00 0.00 C +ATOM 793 CG ASN 82 -11.229 17.242 7.050 1.00 0.00 C +ATOM 794 OD1 ASN 82 -11.630 16.981 8.186 1.00 0.00 O +ATOM 795 ND2 ASN 82 -12.055 17.498 6.039 1.00 0.00 N +ATOM 796 HD21 ASN 82 -13.018 17.460 6.220 1.00 0.00 H +ATOM 797 HD22 ASN 82 -11.683 17.712 5.158 1.00 0.00 H +ATOM 798 C ASN 82 -7.865 16.184 5.467 1.00 0.00 C +ATOM 799 O ASN 82 -6.958 16.906 5.911 1.00 0.00 O +ATOM 800 N LYS 83 -7.781 15.522 4.301 1.00 0.00 N +ATOM 801 H LYS 83 -8.515 14.950 4.012 1.00 0.00 H +ATOM 802 CA LYS 83 -6.654 15.601 3.340 1.00 0.00 C +ATOM 803 CB LYS 83 -5.478 14.689 3.733 1.00 0.00 C +ATOM 804 CG LYS 83 -4.441 15.368 4.623 1.00 0.00 C +ATOM 805 CD LYS 83 -3.159 14.559 4.721 1.00 0.00 C +ATOM 806 CE LYS 83 -2.109 15.290 5.542 1.00 0.00 C +ATOM 807 NZ LYS 83 -0.821 14.544 5.584 1.00 0.00 N +ATOM 808 HZ1 LYS 83 -0.976 13.606 6.004 1.00 0.00 H +ATOM 809 HZ2 LYS 83 -0.454 14.433 4.618 1.00 0.00 H +ATOM 810 HZ3 LYS 83 -0.133 15.073 6.158 1.00 0.00 H +ATOM 811 C LYS 83 -7.112 15.218 1.929 1.00 0.00 C +ATOM 812 O LYS 83 -8.035 14.408 1.775 1.00 0.00 O +ATOM 813 N THR 84 -6.466 15.813 0.916 1.00 0.00 N +ATOM 814 H THR 84 -5.751 16.463 1.095 1.00 0.00 H +ATOM 815 CA THR 84 -6.750 15.563 -0.510 1.00 0.00 C +ATOM 816 CB THR 84 -7.189 16.866 -1.263 1.00 0.00 C +ATOM 817 OG1 THR 84 -6.198 17.888 -1.086 1.00 0.00 O +ATOM 818 HG1 THR 84 -5.364 17.619 -1.478 1.00 0.00 H +ATOM 819 CG2 THR 84 -8.526 17.372 -0.739 1.00 0.00 C +ATOM 820 C THR 84 -5.507 14.962 -1.197 1.00 0.00 C +ATOM 821 O THR 84 -4.377 15.378 -0.903 1.00 0.00 O +ATOM 822 N LEU 85 -5.719 13.960 -2.068 1.00 0.00 N +ATOM 823 H LEU 85 -6.630 13.629 -2.228 1.00 0.00 H +ATOM 824 CA LEU 85 -4.643 13.293 -2.833 1.00 0.00 C +ATOM 825 CB LEU 85 -5.051 11.869 -3.322 1.00 0.00 C +ATOM 826 CG LEU 85 -6.181 11.341 -4.237 1.00 0.00 C +ATOM 827 CD1 LEU 85 -5.978 11.656 -5.713 1.00 0.00 C +ATOM 828 CD2 LEU 85 -6.213 9.835 -4.076 1.00 0.00 C +ATOM 829 C LEU 85 -4.186 14.225 -3.976 1.00 0.00 C +ATOM 830 O LEU 85 -4.998 15.015 -4.467 1.00 0.00 O +ATOM 831 N ALA 86 -2.898 14.182 -4.338 1.00 0.00 N +ATOM 832 H ALA 86 -2.280 13.547 -3.915 1.00 0.00 H +ATOM 833 CA ALA 86 -2.344 15.068 -5.376 1.00 0.00 C +ATOM 834 CB ALA 86 -1.097 15.764 -4.853 1.00 0.00 C +ATOM 835 C ALA 86 -2.050 14.422 -6.736 1.00 0.00 C +ATOM 836 O ALA 86 -1.718 13.235 -6.818 1.00 0.00 O +ATOM 837 N LYS 87 -2.155 15.255 -7.782 1.00 0.00 N +ATOM 838 H LYS 87 -2.377 16.199 -7.609 1.00 0.00 H +ATOM 839 CA LYS 87 -1.954 14.910 -9.203 1.00 0.00 C +ATOM 840 CB LYS 87 -2.639 15.989 -10.064 1.00 0.00 C +ATOM 841 CG LYS 87 -2.809 15.688 -11.564 1.00 0.00 C +ATOM 842 CD LYS 87 -3.381 16.881 -12.313 1.00 0.00 C +ATOM 843 CE LYS 87 -3.546 16.577 -13.793 1.00 0.00 C +ATOM 844 NZ LYS 87 -4.106 17.737 -14.539 1.00 0.00 N +ATOM 845 HZ1 LYS 87 -5.039 17.980 -14.151 1.00 0.00 H +ATOM 846 HZ2 LYS 87 -4.202 17.488 -15.545 1.00 0.00 H +ATOM 847 HZ3 LYS 87 -3.467 18.552 -14.443 1.00 0.00 H +ATOM 848 C LYS 87 -0.466 14.781 -9.597 1.00 0.00 C +ATOM 849 O LYS 87 -0.152 14.156 -10.621 1.00 0.00 O +ATOM 850 N ILE 88 0.428 15.344 -8.771 1.00 0.00 N +ATOM 851 H ILE 88 0.103 15.790 -7.956 1.00 0.00 H +ATOM 852 CA ILE 88 1.889 15.335 -9.005 1.00 0.00 C +ATOM 853 CB ILE 88 2.681 16.156 -7.915 1.00 0.00 C +ATOM 854 CG2 ILE 88 2.514 17.659 -8.194 1.00 0.00 C +ATOM 855 CG1 ILE 88 2.248 15.781 -6.478 1.00 0.00 C +ATOM 856 CD1 ILE 88 3.357 15.873 -5.418 1.00 0.00 C +ATOM 857 C ILE 88 2.538 13.952 -9.261 1.00 0.00 C +ATOM 858 O ILE 88 2.451 13.046 -8.420 1.00 0.00 O +ATOM 859 N LYS 89 3.156 13.819 -10.448 1.00 0.00 N +ATOM 860 H LYS 89 3.177 14.583 -11.066 1.00 0.00 H +ATOM 861 CA LYS 89 3.848 12.613 -10.980 1.00 0.00 C +ATOM 862 CB LYS 89 5.334 12.533 -10.540 1.00 0.00 C +ATOM 863 CG LYS 89 5.668 12.551 -9.038 1.00 0.00 C +ATOM 864 CD LYS 89 7.172 12.510 -8.830 1.00 0.00 C +ATOM 865 CE LYS 89 7.529 12.571 -7.359 1.00 0.00 C +ATOM 866 NZ LYS 89 9.002 12.545 -7.144 1.00 0.00 N +ATOM 867 HZ1 LYS 89 9.436 13.362 -7.618 1.00 0.00 H +ATOM 868 HZ2 LYS 89 9.204 12.589 -6.124 1.00 0.00 H +ATOM 869 HZ3 LYS 89 9.394 11.666 -7.538 1.00 0.00 H +ATOM 870 C LYS 89 3.160 11.232 -10.897 1.00 0.00 C +ATOM 871 O LYS 89 2.431 10.955 -9.939 1.00 0.00 O +ATOM 872 N THR 90 3.435 10.372 -11.898 1.00 0.00 N +ATOM 873 H THR 90 4.047 10.651 -12.614 1.00 0.00 H +ATOM 874 CA THR 90 2.903 8.988 -12.062 1.00 0.00 C +ATOM 875 CB THR 90 3.558 7.951 -11.076 1.00 0.00 C +ATOM 876 OG1 THR 90 4.310 8.633 -10.064 1.00 0.00 O +ATOM 877 HG1 THR 90 5.032 9.128 -10.462 1.00 0.00 H +ATOM 878 CG2 THR 90 4.466 6.998 -11.827 1.00 0.00 C +ATOM 879 C THR 90 1.352 8.826 -12.039 1.00 0.00 C +ATOM 880 O THR 90 0.678 9.613 -11.365 1.00 0.00 O +ATOM 881 N PRO 91 0.761 7.831 -12.784 1.00 0.00 N +ATOM 882 CD PRO 91 -0.670 7.644 -12.474 1.00 0.00 C +ATOM 883 CA PRO 91 1.178 6.747 -13.705 1.00 0.00 C +ATOM 884 CB PRO 91 -0.123 5.975 -13.927 1.00 0.00 C +ATOM 885 CG PRO 91 -0.847 6.160 -12.679 1.00 0.00 C +ATOM 886 C PRO 91 1.798 7.208 -15.041 1.00 0.00 C +ATOM 887 O PRO 91 2.480 6.422 -15.713 1.00 0.00 O +ATOM 888 N LYS 92 1.567 8.480 -15.392 1.00 0.00 N +ATOM 889 H LYS 92 1.027 9.065 -14.818 1.00 0.00 H +ATOM 890 CA LYS 92 2.084 9.097 -16.629 1.00 0.00 C +ATOM 891 CB LYS 92 0.946 9.743 -17.458 1.00 0.00 C +ATOM 892 CG LYS 92 -0.132 10.563 -16.686 1.00 0.00 C +ATOM 893 CD LYS 92 -1.128 11.294 -17.617 1.00 0.00 C +ATOM 894 CE LYS 92 -2.372 10.465 -18.008 1.00 0.00 C +ATOM 895 NZ LYS 92 -3.262 10.148 -16.855 1.00 0.00 N +ATOM 896 HZ1 LYS 92 -3.600 11.032 -16.425 1.00 0.00 H +ATOM 897 HZ2 LYS 92 -2.732 9.598 -16.149 1.00 0.00 H +ATOM 898 HZ3 LYS 92 -4.075 9.591 -17.189 1.00 0.00 H +ATOM 899 C LYS 92 3.249 10.083 -16.391 1.00 0.00 C +ATOM 900 O LYS 92 3.125 11.016 -15.586 1.00 0.00 O +ATOM 901 N GLU 93 4.374 9.841 -17.091 1.00 0.00 N +ATOM 902 H GLU 93 4.401 9.075 -17.705 1.00 0.00 H +ATOM 903 CA GLU 93 5.641 10.626 -17.051 1.00 0.00 C +ATOM 904 CB GLU 93 5.573 11.872 -17.966 1.00 0.00 C +ATOM 905 CG GLU 93 5.508 11.563 -19.459 1.00 0.00 C +ATOM 906 CD GLU 93 5.443 12.815 -20.314 1.00 0.00 C +ATOM 907 OE1 GLU 93 4.322 13.285 -20.600 1.00 0.00 O +ATOM 908 OE2 GLU 93 6.514 13.327 -20.704 1.00 0.00 O +ATOM 909 C GLU 93 6.205 10.996 -15.657 1.00 0.00 C +ATOM 910 O GLU 93 5.706 11.921 -14.999 1.00 0.00 O +ATOM 911 N VAL 94 7.204 10.220 -15.206 1.00 0.00 N +ATOM 912 H VAL 94 7.532 9.471 -15.751 1.00 0.00 H +ATOM 913 CA VAL 94 7.887 10.396 -13.905 1.00 0.00 C +ATOM 914 CB VAL 94 7.316 9.381 -12.799 1.00 0.00 C +ATOM 915 CG1 VAL 94 7.691 7.920 -13.110 1.00 0.00 C +ATOM 916 CG2 VAL 94 7.735 9.795 -11.378 1.00 0.00 C +ATOM 917 C VAL 94 9.419 10.242 -14.093 1.00 0.00 C +ATOM 918 O VAL 94 10.199 10.759 -13.283 1.00 0.00 O +ATOM 919 N ASN 95 9.814 9.559 -15.185 1.00 0.00 N +ATOM 920 H ASN 95 9.131 9.224 -15.807 1.00 0.00 H +ATOM 921 CA ASN 95 11.209 9.231 -15.598 1.00 0.00 C +ATOM 922 CB ASN 95 11.925 10.394 -16.353 1.00 0.00 C +ATOM 923 CG ASN 95 12.058 11.677 -15.525 1.00 0.00 C +ATOM 924 OD1 ASN 95 11.185 12.547 -15.562 1.00 0.00 O +ATOM 925 ND2 ASN 95 13.158 11.797 -14.788 1.00 0.00 N +ATOM 926 HD21 ASN 95 13.824 11.078 -14.802 1.00 0.00 H +ATOM 927 HD22 ASN 95 13.259 12.612 -14.252 1.00 0.00 H +ATOM 928 C ASN 95 12.131 8.555 -14.554 1.00 0.00 C +ATOM 929 O ASN 95 12.623 7.447 -14.798 1.00 0.00 O +ATOM 930 N ALA 96 12.334 9.225 -13.406 1.00 0.00 N +ATOM 931 H ALA 96 11.939 10.111 -13.286 1.00 0.00 H +ATOM 932 CA ALA 96 13.161 8.781 -12.251 1.00 0.00 C +ATOM 933 CB ALA 96 12.384 7.766 -11.370 1.00 0.00 C +ATOM 934 C ALA 96 14.588 8.266 -12.534 1.00 0.00 C +ATOM 935 O ALA 96 14.765 7.282 -13.264 1.00 0.00 O +ATOM 936 N ASP 97 15.585 8.954 -11.959 1.00 0.00 N +ATOM 937 H ASP 97 15.391 9.740 -11.401 1.00 0.00 H +ATOM 938 CA ASP 97 17.011 8.613 -12.102 1.00 0.00 C +ATOM 939 CB ASP 97 17.763 9.724 -12.873 1.00 0.00 C +ATOM 940 CG ASP 97 19.002 9.210 -13.612 1.00 0.00 C +ATOM 941 OD1 ASP 97 18.875 8.815 -14.792 1.00 0.00 O +ATOM 942 OD2 ASP 97 20.101 9.218 -13.017 1.00 0.00 O +ATOM 943 C ASP 97 17.627 8.408 -10.703 1.00 0.00 C +ATOM 944 O ASP 97 18.280 7.384 -10.464 1.00 0.00 O +ATOM 945 N ASP 98 17.412 9.379 -9.801 1.00 0.00 N +ATOM 946 H ASP 98 16.883 10.170 -10.041 1.00 0.00 H +ATOM 947 CA ASP 98 17.932 9.345 -8.421 1.00 0.00 C +ATOM 948 CB ASP 98 19.030 10.421 -8.229 1.00 0.00 C +ATOM 949 CG ASP 98 20.059 10.046 -7.158 1.00 0.00 C +ATOM 950 OD1 ASP 98 21.081 9.414 -7.504 1.00 0.00 O +ATOM 951 OD2 ASP 98 19.850 10.398 -5.976 1.00 0.00 O +ATOM 952 C ASP 98 16.796 9.525 -7.388 1.00 0.00 C +ATOM 953 O ASP 98 16.250 10.628 -7.232 1.00 0.00 O +ATOM 954 N TYR 99 16.417 8.412 -6.742 1.00 0.00 N +ATOM 955 H TYR 99 16.839 7.550 -6.954 1.00 0.00 H +ATOM 956 CA TYR 99 15.376 8.353 -5.695 1.00 0.00 C +ATOM 957 CB TYR 99 13.967 8.068 -6.286 1.00 0.00 C +ATOM 958 CG TYR 99 13.271 9.263 -6.949 1.00 0.00 C +ATOM 959 CD1 TYR 99 12.516 10.189 -6.184 1.00 0.00 C +ATOM 960 CE1 TYR 99 11.853 11.287 -6.797 1.00 0.00 C +ATOM 961 CD2 TYR 99 13.344 9.468 -8.349 1.00 0.00 C +ATOM 962 CE2 TYR 99 12.683 10.566 -8.969 1.00 0.00 C +ATOM 963 CZ TYR 99 11.943 11.465 -8.186 1.00 0.00 C +ATOM 964 OH TYR 99 11.304 12.527 -8.786 1.00 0.00 O +ATOM 965 HH TYR 99 10.841 13.052 -8.129 1.00 0.00 H +ATOM 966 C TYR 99 15.758 7.292 -4.655 1.00 0.00 C +ATOM 967 O TYR 99 16.551 6.392 -4.957 1.00 0.00 O +ATOM 968 N GLN 100 15.187 7.404 -3.447 1.00 0.00 N +ATOM 969 H GLN 100 14.541 8.121 -3.271 1.00 0.00 H +ATOM 970 CA GLN 100 15.465 6.499 -2.319 1.00 0.00 C +ATOM 971 CB GLN 100 15.550 7.328 -1.015 1.00 0.00 C +ATOM 972 CG GLN 100 16.241 6.651 0.180 1.00 0.00 C +ATOM 973 CD GLN 100 16.068 7.414 1.483 1.00 0.00 C +ATOM 974 OE1 GLN 100 17.032 7.942 2.032 1.00 0.00 O +ATOM 975 NE2 GLN 100 14.840 7.454 1.997 1.00 0.00 N +ATOM 976 HE21 GLN 100 14.715 7.943 2.837 1.00 0.00 H +ATOM 977 HE22 GLN 100 14.110 7.000 1.527 1.00 0.00 H +ATOM 978 C GLN 100 14.507 5.282 -2.175 1.00 0.00 C +ATOM 979 O GLN 100 14.718 4.255 -2.831 1.00 0.00 O +ATOM 980 N ILE 101 13.474 5.419 -1.328 1.00 0.00 N +ATOM 981 H ILE 101 13.305 6.270 -0.871 1.00 0.00 H +ATOM 982 CA ILE 101 12.494 4.360 -1.011 1.00 0.00 C +ATOM 983 CB ILE 101 12.338 4.181 0.561 1.00 0.00 C +ATOM 984 CG2 ILE 101 11.529 2.887 0.894 1.00 0.00 C +ATOM 985 CG1 ILE 101 13.727 4.070 1.220 1.00 0.00 C +ATOM 986 CD1 ILE 101 13.818 4.522 2.685 1.00 0.00 C +ATOM 987 C ILE 101 11.108 4.567 -1.663 1.00 0.00 C +ATOM 988 O ILE 101 10.668 5.707 -1.857 1.00 0.00 O +ATOM 989 N PHE 102 10.478 3.446 -2.045 1.00 0.00 N +ATOM 990 H PHE 102 10.911 2.571 -1.932 1.00 0.00 H +ATOM 991 CA PHE 102 9.135 3.401 -2.649 1.00 0.00 C +ATOM 992 CB PHE 102 9.151 2.574 -3.974 1.00 0.00 C +ATOM 993 CG PHE 102 7.779 2.394 -4.650 1.00 0.00 C +ATOM 994 CD1 PHE 102 7.205 3.423 -5.432 1.00 0.00 C +ATOM 995 CD2 PHE 102 7.065 1.179 -4.512 1.00 0.00 C +ATOM 996 CE1 PHE 102 5.943 3.250 -6.064 1.00 0.00 C +ATOM 997 CE2 PHE 102 5.803 0.991 -5.138 1.00 0.00 C +ATOM 998 CZ PHE 102 5.241 2.030 -5.916 1.00 0.00 C +ATOM 999 C PHE 102 8.160 2.775 -1.632 1.00 0.00 C +ATOM 1000 O PHE 102 8.489 1.772 -0.985 1.00 0.00 O +ATOM 1001 N PHE 103 6.984 3.399 -1.491 1.00 0.00 N +ATOM 1002 H PHE 103 6.791 4.218 -1.998 1.00 0.00 H +ATOM 1003 CA PHE 103 5.908 2.942 -0.600 1.00 0.00 C +ATOM 1004 CB PHE 103 5.712 3.908 0.602 1.00 0.00 C +ATOM 1005 CG PHE 103 6.622 3.634 1.795 1.00 0.00 C +ATOM 1006 CD1 PHE 103 6.151 2.886 2.900 1.00 0.00 C +ATOM 1007 CD2 PHE 103 7.939 4.149 1.842 1.00 0.00 C +ATOM 1008 CE1 PHE 103 6.975 2.654 4.036 1.00 0.00 C +ATOM 1009 CE2 PHE 103 8.773 3.925 2.969 1.00 0.00 C +ATOM 1010 CZ PHE 103 8.290 3.175 4.069 1.00 0.00 C +ATOM 1011 C PHE 103 4.614 2.814 -1.412 1.00 0.00 C +ATOM 1012 O PHE 103 4.302 3.689 -2.224 1.00 0.00 O +ATOM 1013 N ALA 104 3.910 1.689 -1.237 1.00 0.00 N +ATOM 1014 H ALA 104 4.225 0.991 -0.622 1.00 0.00 H +ATOM 1015 CA ALA 104 2.643 1.411 -1.932 1.00 0.00 C +ATOM 1016 CB ALA 104 2.702 0.043 -2.630 1.00 0.00 C +ATOM 1017 C ALA 104 1.492 1.467 -0.915 1.00 0.00 C +ATOM 1018 O ALA 104 1.262 0.500 -0.175 1.00 0.00 O +ATOM 1019 N SER 105 0.815 2.623 -0.854 1.00 0.00 N +ATOM 1020 H SER 105 1.049 3.376 -1.441 1.00 0.00 H +ATOM 1021 CA SER 105 -0.303 2.849 0.073 1.00 0.00 C +ATOM 1022 CB SER 105 -0.213 4.229 0.732 1.00 0.00 C +ATOM 1023 OG SER 105 0.990 4.367 1.470 1.00 0.00 O +ATOM 1024 HG SER 105 1.015 3.740 2.199 1.00 0.00 H +ATOM 1025 C SER 105 -1.703 2.601 -0.500 1.00 0.00 C +ATOM 1026 O SER 105 -2.188 3.350 -1.359 1.00 0.00 O +ATOM 1027 N ALA 106 -2.300 1.492 -0.049 1.00 0.00 N +ATOM 1028 H ALA 106 -1.844 0.900 0.590 1.00 0.00 H +ATOM 1029 CA ALA 106 -3.644 1.045 -0.435 1.00 0.00 C +ATOM 1030 CB ALA 106 -3.568 0.011 -1.545 1.00 0.00 C +ATOM 1031 C ALA 106 -4.312 0.455 0.808 1.00 0.00 C +ATOM 1032 O ALA 106 -3.617 0.005 1.727 1.00 0.00 O +ATOM 1033 N GLY 107 -5.647 0.453 0.826 1.00 0.00 N +ATOM 1034 H GLY 107 -6.171 0.793 0.068 1.00 0.00 H +ATOM 1035 CA GLY 107 -6.390 -0.056 1.970 1.00 0.00 C +ATOM 1036 C GLY 107 -7.321 -1.224 1.705 1.00 0.00 C +ATOM 1037 O GLY 107 -6.871 -2.371 1.617 1.00 0.00 O +ATOM 1038 N HIS 108 -8.619 -0.918 1.596 1.00 0.00 N +ATOM 1039 H HIS 108 -8.889 0.019 1.667 1.00 0.00 H +ATOM 1040 CA HIS 108 -9.691 -1.897 1.362 1.00 0.00 C +ATOM 1041 CB HIS 108 -10.847 -1.621 2.354 1.00 0.00 C +ATOM 1042 CG HIS 108 -11.762 -2.791 2.591 1.00 0.00 C +ATOM 1043 CD2 HIS 108 -13.070 -2.976 2.286 1.00 0.00 C +ATOM 1044 ND1 HIS 108 -11.356 -3.943 3.231 1.00 0.00 N +ATOM 1045 HD1 HIS 108 -10.457 -4.112 3.573 1.00 0.00 H +ATOM 1046 CE1 HIS 108 -12.370 -4.786 3.310 1.00 0.00 C +ATOM 1047 NE2 HIS 108 -13.422 -4.223 2.744 1.00 0.00 N +ATOM 1048 HE2 HIS 108 -14.310 -4.629 2.663 1.00 0.00 H +ATOM 1049 C HIS 108 -10.184 -1.843 -0.100 1.00 0.00 C +ATOM 1050 O HIS 108 -11.197 -2.468 -0.447 1.00 0.00 O +ATOM 1051 N GLY 109 -9.437 -1.129 -0.952 1.00 0.00 N +ATOM 1052 H GLY 109 -8.620 -0.675 -0.650 1.00 0.00 H +ATOM 1053 CA GLY 109 -9.782 -0.984 -2.365 1.00 0.00 C +ATOM 1054 C GLY 109 -9.464 -2.192 -3.231 1.00 0.00 C +ATOM 1055 O GLY 109 -8.824 -2.046 -4.277 1.00 0.00 O +ATOM 1056 N THR 110 -9.943 -3.368 -2.784 1.00 0.00 N +ATOM 1057 H THR 110 -10.462 -3.376 -1.958 1.00 0.00 H +ATOM 1058 CA THR 110 -9.790 -4.709 -3.409 1.00 0.00 C +ATOM 1059 CB THR 110 -11.048 -5.124 -4.240 1.00 0.00 C +ATOM 1060 OG1 THR 110 -11.346 -4.108 -5.206 1.00 0.00 O +ATOM 1061 HG1 THR 110 -10.627 -4.021 -5.838 1.00 0.00 H +ATOM 1062 CG2 THR 110 -12.255 -5.333 -3.333 1.00 0.00 C +ATOM 1063 C THR 110 -8.504 -4.971 -4.222 1.00 0.00 C +ATOM 1064 O THR 110 -7.650 -5.755 -3.790 1.00 0.00 O +ATOM 1065 N LEU 111 -8.388 -4.313 -5.386 1.00 0.00 N +ATOM 1066 H LEU 111 -9.111 -3.719 -5.684 1.00 0.00 H +ATOM 1067 CA LEU 111 -7.237 -4.397 -6.303 1.00 0.00 C +ATOM 1068 CB LEU 111 -7.399 -5.541 -7.332 1.00 0.00 C +ATOM 1069 CG LEU 111 -7.314 -7.043 -6.994 1.00 0.00 C +ATOM 1070 CD1 LEU 111 -8.688 -7.641 -6.642 1.00 0.00 C +ATOM 1071 CD2 LEU 111 -6.746 -7.775 -8.200 1.00 0.00 C +ATOM 1072 C LEU 111 -7.125 -3.059 -7.046 1.00 0.00 C +ATOM 1073 O LEU 111 -6.036 -2.477 -7.104 1.00 0.00 O +ATOM 1074 N PHE 112 -8.267 -2.580 -7.577 1.00 0.00 N +ATOM 1075 H PHE 112 -9.099 -3.090 -7.464 1.00 0.00 H +ATOM 1076 CA PHE 112 -8.441 -1.319 -8.349 1.00 0.00 C +ATOM 1077 CB PHE 112 -9.145 -0.228 -7.486 1.00 0.00 C +ATOM 1078 CG PHE 112 -10.646 -0.435 -7.294 1.00 0.00 C +ATOM 1079 CD1 PHE 112 -11.143 -1.143 -6.174 1.00 0.00 C +ATOM 1080 CD2 PHE 112 -11.576 0.113 -8.210 1.00 0.00 C +ATOM 1081 CE1 PHE 112 -12.541 -1.305 -5.968 1.00 0.00 C +ATOM 1082 CE2 PHE 112 -12.977 -0.039 -8.017 1.00 0.00 C +ATOM 1083 CZ PHE 112 -13.460 -0.751 -6.892 1.00 0.00 C +ATOM 1084 C PHE 112 -7.223 -0.737 -9.103 1.00 0.00 C +ATOM 1085 O PHE 112 -6.523 0.151 -8.592 1.00 0.00 O +ATOM 1086 N ASP 113 -6.974 -1.283 -10.307 1.00 0.00 N +ATOM 1087 H ASP 113 -7.557 -1.999 -10.644 1.00 0.00 H +ATOM 1088 CA ASP 113 -5.871 -0.917 -11.237 1.00 0.00 C +ATOM 1089 CB ASP 113 -6.247 0.319 -12.094 1.00 0.00 C +ATOM 1090 CG ASP 113 -7.422 0.056 -13.031 1.00 0.00 C +ATOM 1091 OD1 ASP 113 -7.186 -0.368 -14.184 1.00 0.00 O +ATOM 1092 OD2 ASP 113 -8.580 0.291 -12.622 1.00 0.00 O +ATOM 1093 C ASP 113 -4.465 -0.764 -10.600 1.00 0.00 C +ATOM 1094 O ASP 113 -3.731 0.190 -10.901 1.00 0.00 O +ATOM 1095 N TYR 114 -4.125 -1.701 -9.701 1.00 0.00 N +ATOM 1096 H TYR 114 -4.753 -2.421 -9.478 1.00 0.00 H +ATOM 1097 CA TYR 114 -2.831 -1.731 -8.992 1.00 0.00 C +ATOM 1098 CB TYR 114 -3.003 -1.396 -7.482 1.00 0.00 C +ATOM 1099 CG TYR 114 -2.614 0.016 -7.040 1.00 0.00 C +ATOM 1100 CD1 TYR 114 -1.325 0.284 -6.517 1.00 0.00 C +ATOM 1101 CE1 TYR 114 -0.963 1.585 -6.078 1.00 0.00 C +ATOM 1102 CD2 TYR 114 -3.536 1.090 -7.110 1.00 0.00 C +ATOM 1103 CE2 TYR 114 -3.181 2.395 -6.674 1.00 0.00 C +ATOM 1104 CZ TYR 114 -1.895 2.630 -6.162 1.00 0.00 C +ATOM 1105 OH TYR 114 -1.540 3.893 -5.750 1.00 0.00 O +ATOM 1106 HH TYR 114 -2.255 4.509 -5.920 1.00 0.00 H +ATOM 1107 C TYR 114 -2.021 -3.046 -9.162 1.00 0.00 C +ATOM 1108 O TYR 114 -0.827 -2.964 -9.476 1.00 0.00 O +ATOM 1109 N PRO 115 -2.634 -4.266 -8.964 1.00 0.00 N +ATOM 1110 CD PRO 115 -3.969 -4.621 -8.430 1.00 0.00 C +ATOM 1111 CA PRO 115 -1.848 -5.512 -9.126 1.00 0.00 C +ATOM 1112 CB PRO 115 -2.747 -6.580 -8.481 1.00 0.00 C +ATOM 1113 CG PRO 115 -3.647 -5.810 -7.579 1.00 0.00 C +ATOM 1114 C PRO 115 -1.484 -5.905 -10.577 1.00 0.00 C +ATOM 1115 O PRO 115 -0.388 -6.423 -10.821 1.00 0.00 O +ATOM 1116 N LYS 116 -2.413 -5.650 -11.509 1.00 0.00 N +ATOM 1117 H LYS 116 -3.267 -5.235 -11.256 1.00 0.00 H +ATOM 1118 CA LYS 116 -2.256 -5.951 -12.945 1.00 0.00 C +ATOM 1119 CB LYS 116 -3.533 -6.612 -13.494 1.00 0.00 C +ATOM 1120 CG LYS 116 -3.795 -8.023 -12.978 1.00 0.00 C +ATOM 1121 CD LYS 116 -5.076 -8.601 -13.570 1.00 0.00 C +ATOM 1122 CE LYS 116 -5.358 -10.015 -13.067 1.00 0.00 C +ATOM 1123 NZ LYS 116 -4.386 -11.033 -13.568 1.00 0.00 N +ATOM 1124 HZ1 LYS 116 -3.427 -10.778 -13.257 1.00 0.00 H +ATOM 1125 HZ2 LYS 116 -4.418 -11.061 -14.607 1.00 0.00 H +ATOM 1126 HZ3 LYS 116 -4.637 -11.968 -13.188 1.00 0.00 H +ATOM 1127 C LYS 116 -1.911 -4.674 -13.742 1.00 0.00 C +ATOM 1128 O LYS 116 -1.901 -4.684 -14.983 1.00 0.00 O +ATOM 1129 N ALA 117 -1.570 -3.605 -13.007 1.00 0.00 N +ATOM 1130 H ALA 117 -1.551 -3.663 -12.026 1.00 0.00 H +ATOM 1131 CA ALA 117 -1.206 -2.288 -13.563 1.00 0.00 C +ATOM 1132 CB ALA 117 -1.479 -1.196 -12.538 1.00 0.00 C +ATOM 1133 C ALA 117 0.259 -2.224 -14.026 1.00 0.00 C +ATOM 1134 O ALA 117 1.170 -2.555 -13.259 1.00 0.00 O +ATOM 1135 N LYS 118 0.461 -1.821 -15.287 1.00 0.00 N +ATOM 1136 H LYS 118 -0.310 -1.581 -15.848 1.00 0.00 H +ATOM 1137 CA LYS 118 1.788 -1.699 -15.924 1.00 0.00 C +ATOM 1138 CB LYS 118 1.647 -1.571 -17.449 1.00 0.00 C +ATOM 1139 CG LYS 118 1.156 -2.831 -18.154 1.00 0.00 C +ATOM 1140 CD LYS 118 1.044 -2.617 -19.654 1.00 0.00 C +ATOM 1141 CE LYS 118 0.555 -3.873 -20.357 1.00 0.00 C +ATOM 1142 NZ LYS 118 0.441 -3.677 -21.828 1.00 0.00 N +ATOM 1143 HZ1 LYS 118 0.105 -4.557 -22.270 1.00 0.00 H +ATOM 1144 HZ2 LYS 118 -0.233 -2.911 -22.025 1.00 0.00 H +ATOM 1145 HZ3 LYS 118 1.373 -3.428 -22.218 1.00 0.00 H +ATOM 1146 C LYS 118 2.684 -0.568 -15.388 1.00 0.00 C +ATOM 1147 O LYS 118 3.856 -0.809 -15.094 1.00 0.00 O +ATOM 1148 N ASP 119 2.107 0.632 -15.217 1.00 0.00 N +ATOM 1149 H ASP 119 1.149 0.734 -15.414 1.00 0.00 H +ATOM 1150 CA ASP 119 2.811 1.844 -14.739 1.00 0.00 C +ATOM 1151 CB ASP 119 1.943 3.091 -14.980 1.00 0.00 C +ATOM 1152 CG ASP 119 1.702 3.371 -16.462 1.00 0.00 C +ATOM 1153 OD1 ASP 119 2.519 4.089 -17.079 1.00 0.00 O +ATOM 1154 OD2 ASP 119 0.685 2.885 -17.005 1.00 0.00 O +ATOM 1155 C ASP 119 3.297 1.829 -13.276 1.00 0.00 C +ATOM 1156 O ASP 119 4.456 2.177 -13.010 1.00 0.00 O +ATOM 1157 N LEU 120 2.423 1.403 -12.351 1.00 0.00 N +ATOM 1158 H LEU 120 1.524 1.118 -12.628 1.00 0.00 H +ATOM 1159 CA LEU 120 2.721 1.323 -10.904 1.00 0.00 C +ATOM 1160 CB LEU 120 1.431 1.105 -10.086 1.00 0.00 C +ATOM 1161 CG LEU 120 0.337 2.194 -10.032 1.00 0.00 C +ATOM 1162 CD1 LEU 120 -1.017 1.524 -9.906 1.00 0.00 C +ATOM 1163 CD2 LEU 120 0.547 3.208 -8.892 1.00 0.00 C +ATOM 1164 C LEU 120 3.761 0.234 -10.591 1.00 0.00 C +ATOM 1165 O LEU 120 4.673 0.448 -9.778 1.00 0.00 O +ATOM 1166 N GLN 121 3.613 -0.920 -11.255 1.00 0.00 N +ATOM 1167 H GLN 121 2.859 -1.037 -11.875 1.00 0.00 H +ATOM 1168 CA GLN 121 4.526 -2.068 -11.123 1.00 0.00 C +ATOM 1169 CB GLN 121 3.895 -3.348 -11.703 1.00 0.00 C +ATOM 1170 CG GLN 121 2.724 -3.941 -10.884 1.00 0.00 C +ATOM 1171 CD GLN 121 3.151 -4.979 -9.845 1.00 0.00 C +ATOM 1172 OE1 GLN 121 3.734 -4.642 -8.813 1.00 0.00 O +ATOM 1173 NE2 GLN 121 2.848 -6.243 -10.114 1.00 0.00 N +ATOM 1174 HE21 GLN 121 3.113 -6.921 -9.459 1.00 0.00 H +ATOM 1175 HE22 GLN 121 2.375 -6.456 -10.946 1.00 0.00 H +ATOM 1176 C GLN 121 5.901 -1.774 -11.753 1.00 0.00 C +ATOM 1177 O GLN 121 6.932 -2.175 -11.202 1.00 0.00 O +ATOM 1178 N ASP 122 5.900 -1.021 -12.867 1.00 0.00 N +ATOM 1179 H ASP 122 5.044 -0.708 -13.243 1.00 0.00 H +ATOM 1180 CA ASP 122 7.120 -0.623 -13.606 1.00 0.00 C +ATOM 1181 CB ASP 122 6.758 0.014 -14.962 1.00 0.00 C +ATOM 1182 CG ASP 122 7.824 -0.214 -16.038 1.00 0.00 C +ATOM 1183 OD1 ASP 122 7.734 -1.227 -16.767 1.00 0.00 O +ATOM 1184 OD2 ASP 122 8.740 0.628 -16.163 1.00 0.00 O +ATOM 1185 C ASP 122 7.987 0.347 -12.777 1.00 0.00 C +ATOM 1186 O ASP 122 9.211 0.185 -12.737 1.00 0.00 O +ATOM 1187 N ILE 123 7.350 1.327 -12.112 1.00 0.00 N +ATOM 1188 H ILE 123 6.372 1.417 -12.185 1.00 0.00 H +ATOM 1189 CA ILE 123 8.059 2.309 -11.261 1.00 0.00 C +ATOM 1190 CB ILE 123 7.214 3.614 -10.940 1.00 0.00 C +ATOM 1191 CG2 ILE 123 7.066 4.442 -12.227 1.00 0.00 C +ATOM 1192 CG1 ILE 123 5.851 3.294 -10.296 1.00 0.00 C +ATOM 1193 CD1 ILE 123 5.271 4.391 -9.388 1.00 0.00 C +ATOM 1194 C ILE 123 8.661 1.646 -10.002 1.00 0.00 C +ATOM 1195 O ILE 123 9.775 1.993 -9.592 1.00 0.00 O +ATOM 1196 N ALA 124 7.936 0.662 -9.443 1.00 0.00 N +ATOM 1197 H ALA 124 7.043 0.436 -9.802 1.00 0.00 H +ATOM 1198 CA ALA 124 8.368 -0.121 -8.264 1.00 0.00 C +ATOM 1199 CB ALA 124 7.222 -1.005 -7.754 1.00 0.00 C +ATOM 1200 C ALA 124 9.571 -0.995 -8.665 1.00 0.00 C +ATOM 1201 O ALA 124 10.525 -1.145 -7.891 1.00 0.00 O +ATOM 1202 N SER 125 9.512 -1.525 -9.897 1.00 0.00 N +ATOM 1203 H SER 125 8.723 -1.346 -10.458 1.00 0.00 H +ATOM 1204 CA SER 125 10.553 -2.377 -10.510 1.00 0.00 C +ATOM 1205 CB SER 125 10.022 -3.023 -11.797 1.00 0.00 C +ATOM 1206 OG SER 125 10.917 -4.001 -12.304 1.00 0.00 O +ATOM 1207 HG SER 125 10.554 -4.382 -13.106 1.00 0.00 H +ATOM 1208 C SER 125 11.833 -1.574 -10.809 1.00 0.00 C +ATOM 1209 O SER 125 12.942 -2.095 -10.649 1.00 0.00 O +ATOM 1210 N GLU 126 11.656 -0.311 -11.232 1.00 0.00 N +ATOM 1211 H GLU 126 10.744 0.039 -11.340 1.00 0.00 H +ATOM 1212 CA GLU 126 12.754 0.627 -11.555 1.00 0.00 C +ATOM 1213 CB GLU 126 12.221 1.873 -12.276 1.00 0.00 C +ATOM 1214 CG GLU 126 11.863 1.652 -13.741 1.00 0.00 C +ATOM 1215 CD GLU 126 11.341 2.908 -14.413 1.00 0.00 C +ATOM 1216 OE1 GLU 126 12.160 3.671 -14.970 1.00 0.00 O +ATOM 1217 OE2 GLU 126 10.113 3.132 -14.388 1.00 0.00 O +ATOM 1218 C GLU 126 13.550 1.039 -10.306 1.00 0.00 C +ATOM 1219 O GLU 126 14.784 1.064 -10.344 1.00 0.00 O +ATOM 1220 N ILE 127 12.834 1.324 -9.205 1.00 0.00 N +ATOM 1221 H ILE 127 11.849 1.278 -9.253 1.00 0.00 H +ATOM 1222 CA ILE 127 13.426 1.713 -7.903 1.00 0.00 C +ATOM 1223 CB ILE 127 12.350 2.329 -6.918 1.00 0.00 C +ATOM 1224 CG2 ILE 127 12.995 2.710 -5.549 1.00 0.00 C +ATOM 1225 CG1 ILE 127 11.751 3.601 -7.554 1.00 0.00 C +ATOM 1226 CD1 ILE 127 10.300 3.923 -7.183 1.00 0.00 C +ATOM 1227 C ILE 127 14.170 0.494 -7.307 1.00 0.00 C +ATOM 1228 O ILE 127 15.221 0.658 -6.676 1.00 0.00 O +ATOM 1229 N TYR 128 13.611 -0.708 -7.522 1.00 0.00 N +ATOM 1230 H TYR 128 12.748 -0.761 -7.999 1.00 0.00 H +ATOM 1231 CA TYR 128 14.186 -1.994 -7.072 1.00 0.00 C +ATOM 1232 CB TYR 128 13.152 -3.143 -7.260 1.00 0.00 C +ATOM 1233 CG TYR 128 13.445 -4.481 -6.555 1.00 0.00 C +ATOM 1234 CD1 TYR 128 13.016 -4.720 -5.225 1.00 0.00 C +ATOM 1235 CE1 TYR 128 13.263 -5.964 -4.582 1.00 0.00 C +ATOM 1236 CD2 TYR 128 14.128 -5.525 -7.226 1.00 0.00 C +ATOM 1237 CE2 TYR 128 14.379 -6.772 -6.590 1.00 0.00 C +ATOM 1238 CZ TYR 128 13.943 -6.980 -5.272 1.00 0.00 C +ATOM 1239 OH TYR 128 14.182 -8.185 -4.650 1.00 0.00 O +ATOM 1240 HH TYR 128 14.653 -8.778 -5.241 1.00 0.00 H +ATOM 1241 C TYR 128 15.476 -2.285 -7.878 1.00 0.00 C +ATOM 1242 O TYR 128 16.445 -2.826 -7.334 1.00 0.00 O +ATOM 1243 N ALA 129 15.450 -1.911 -9.167 1.00 0.00 N +ATOM 1244 H ALA 129 14.641 -1.484 -9.530 1.00 0.00 H +ATOM 1245 CA ALA 129 16.553 -2.083 -10.134 1.00 0.00 C +ATOM 1246 CB ALA 129 16.035 -1.879 -11.553 1.00 0.00 C +ATOM 1247 C ALA 129 17.812 -1.223 -9.906 1.00 0.00 C +ATOM 1248 O ALA 129 18.927 -1.707 -10.127 1.00 0.00 O +ATOM 1249 N ASN 130 17.625 0.031 -9.465 1.00 0.00 N +ATOM 1250 H ASN 130 16.713 0.354 -9.293 1.00 0.00 H +ATOM 1251 CA ASN 130 18.722 0.992 -9.207 1.00 0.00 C +ATOM 1252 CB ASN 130 18.182 2.433 -9.145 1.00 0.00 C +ATOM 1253 CG ASN 130 17.814 2.987 -10.517 1.00 0.00 C +ATOM 1254 OD1 ASN 130 18.679 3.429 -11.279 1.00 0.00 O +ATOM 1255 ND2 ASN 130 16.522 2.997 -10.822 1.00 0.00 N +ATOM 1256 HD21 ASN 130 16.265 3.336 -11.705 1.00 0.00 H +ATOM 1257 HD22 ASN 130 15.874 2.680 -10.160 1.00 0.00 H +ATOM 1258 C ASN 130 19.575 0.700 -7.960 1.00 0.00 C +ATOM 1259 O ASN 130 20.776 0.995 -7.948 1.00 0.00 O +ATOM 1260 N GLY 131 18.950 0.112 -6.935 1.00 0.00 N +ATOM 1261 H GLY 131 17.996 -0.114 -6.982 1.00 0.00 H +ATOM 1262 CA GLY 131 19.648 -0.223 -5.700 1.00 0.00 C +ATOM 1263 C GLY 131 18.975 0.343 -4.465 1.00 0.00 C +ATOM 1264 O GLY 131 19.634 0.560 -3.442 1.00 0.00 O +ATOM 1265 N GLY 132 17.665 0.578 -4.572 1.00 0.00 N +ATOM 1266 H GLY 132 17.204 0.387 -5.416 1.00 0.00 H +ATOM 1267 CA GLY 132 16.879 1.114 -3.470 1.00 0.00 C +ATOM 1268 C GLY 132 15.930 0.072 -2.902 1.00 0.00 C +ATOM 1269 O GLY 132 15.617 -0.912 -3.582 1.00 0.00 O +ATOM 1270 N VAL 133 15.479 0.296 -1.661 1.00 0.00 N +ATOM 1271 H VAL 133 15.773 1.106 -1.192 1.00 0.00 H +ATOM 1272 CA VAL 133 14.558 -0.604 -0.944 1.00 0.00 C +ATOM 1273 CB VAL 133 14.899 -0.701 0.591 1.00 0.00 C +ATOM 1274 CG1 VAL 133 16.142 -1.559 0.790 1.00 0.00 C +ATOM 1275 CG2 VAL 133 15.130 0.685 1.222 1.00 0.00 C +ATOM 1276 C VAL 133 13.062 -0.286 -1.165 1.00 0.00 C +ATOM 1277 O VAL 133 12.687 0.889 -1.270 1.00 0.00 O +ATOM 1278 N VAL 134 12.239 -1.341 -1.266 1.00 0.00 N +ATOM 1279 H VAL 134 12.592 -2.254 -1.191 1.00 0.00 H +ATOM 1280 CA VAL 134 10.782 -1.234 -1.491 1.00 0.00 C +ATOM 1281 CB VAL 134 10.319 -2.048 -2.773 1.00 0.00 C +ATOM 1282 CG1 VAL 134 8.900 -1.641 -3.214 1.00 0.00 C +ATOM 1283 CG2 VAL 134 11.291 -1.831 -3.933 1.00 0.00 C +ATOM 1284 C VAL 134 9.999 -1.720 -0.251 1.00 0.00 C +ATOM 1285 O VAL 134 10.360 -2.733 0.364 1.00 0.00 O +ATOM 1286 N ALA 135 8.989 -0.933 0.141 1.00 0.00 N +ATOM 1287 H ALA 135 8.802 -0.094 -0.331 1.00 0.00 H +ATOM 1288 CA ALA 135 8.091 -1.229 1.269 1.00 0.00 C +ATOM 1289 CB ALA 135 8.349 -0.279 2.443 1.00 0.00 C +ATOM 1290 C ALA 135 6.650 -1.081 0.770 1.00 0.00 C +ATOM 1291 O ALA 135 6.360 -0.162 0.002 1.00 0.00 O +ATOM 1292 N ALA 136 5.777 -2.018 1.158 1.00 0.00 N +ATOM 1293 H ALA 136 6.068 -2.764 1.728 1.00 0.00 H +ATOM 1294 CA ALA 136 4.352 -2.017 0.780 1.00 0.00 C +ATOM 1295 CB ALA 136 4.050 -3.152 -0.185 1.00 0.00 C +ATOM 1296 C ALA 136 3.507 -2.154 2.046 1.00 0.00 C +ATOM 1297 O ALA 136 3.906 -2.871 2.972 1.00 0.00 O +ATOM 1298 N VAL 137 2.354 -1.470 2.084 1.00 0.00 N +ATOM 1299 H VAL 137 2.069 -0.918 1.323 1.00 0.00 H +ATOM 1300 CA VAL 137 1.454 -1.501 3.253 1.00 0.00 C +ATOM 1301 CB VAL 137 1.200 -0.057 3.876 1.00 0.00 C +ATOM 1302 CG1 VAL 137 2.510 0.556 4.360 1.00 0.00 C +ATOM 1303 CG2 VAL 137 0.527 0.880 2.893 1.00 0.00 C +ATOM 1304 C VAL 137 0.133 -2.278 3.071 1.00 0.00 C +ATOM 1305 O VAL 137 -0.637 -1.999 2.142 1.00 0.00 O +ATOM 1306 N CYS 138 -0.099 -3.250 3.976 1.00 0.00 N +ATOM 1307 H CYS 138 0.563 -3.416 4.683 1.00 0.00 H +ATOM 1308 CA CYS 138 -1.286 -4.151 4.049 1.00 0.00 C +ATOM 1309 CB CYS 138 -2.457 -3.461 4.775 1.00 0.00 C +ATOM 1310 SG CYS 138 -3.084 -1.959 3.984 1.00 0.00 S +ATOM 1311 C CYS 138 -1.765 -4.777 2.720 1.00 0.00 C +ATOM 1312 O CYS 138 -1.609 -5.985 2.503 1.00 0.00 O +ATOM 1313 N HIS 139 -2.403 -3.944 1.889 1.00 0.00 N +ATOM 1314 H HIS 139 -2.525 -3.013 2.172 1.00 0.00 H +ATOM 1315 CA HIS 139 -2.929 -4.249 0.551 1.00 0.00 C +ATOM 1316 CB HIS 139 -3.890 -3.134 0.136 1.00 0.00 C +ATOM 1317 CG HIS 139 -5.128 -3.606 -0.568 1.00 0.00 C +ATOM 1318 CD2 HIS 139 -5.681 -3.220 -1.742 1.00 0.00 C +ATOM 1319 ND1 HIS 139 -5.987 -4.543 -0.032 1.00 0.00 N +ATOM 1320 HD1 HIS 139 -5.861 -5.014 0.818 1.00 0.00 H +ATOM 1321 CE1 HIS 139 -7.016 -4.710 -0.843 1.00 0.00 C +ATOM 1322 NE2 HIS 139 -6.854 -3.918 -1.886 1.00 0.00 N +ATOM 1323 HE2 HIS 139 -7.472 -3.768 -2.617 1.00 0.00 H +ATOM 1324 C HIS 139 -1.773 -4.394 -0.454 1.00 0.00 C +ATOM 1325 O HIS 139 -1.868 -5.156 -1.424 1.00 0.00 O +ATOM 1326 N GLY 140 -0.707 -3.617 -0.209 1.00 0.00 N +ATOM 1327 H GLY 140 -0.692 -3.012 0.558 1.00 0.00 H +ATOM 1328 CA GLY 140 0.492 -3.600 -1.044 1.00 0.00 C +ATOM 1329 C GLY 140 1.180 -4.957 -1.220 1.00 0.00 C +ATOM 1330 O GLY 140 1.620 -5.218 -2.347 1.00 0.00 O +ATOM 1331 N PRO 141 1.336 -5.822 -0.164 1.00 0.00 N +ATOM 1332 CD PRO 141 1.254 -5.476 1.274 1.00 0.00 C +ATOM 1333 CA PRO 141 1.974 -7.146 -0.305 1.00 0.00 C +ATOM 1334 CB PRO 141 1.802 -7.748 1.087 1.00 0.00 C +ATOM 1335 CG PRO 141 2.031 -6.584 1.949 1.00 0.00 C +ATOM 1336 C PRO 141 1.202 -7.968 -1.352 1.00 0.00 C +ATOM 1337 O PRO 141 1.798 -8.713 -2.138 1.00 0.00 O +ATOM 1338 N ALA 142 -0.127 -7.782 -1.347 1.00 0.00 N +ATOM 1339 H ALA 142 -0.528 -7.174 -0.685 1.00 0.00 H +ATOM 1340 CA ALA 142 -1.081 -8.417 -2.268 1.00 0.00 C +ATOM 1341 CB ALA 142 -2.496 -8.225 -1.746 1.00 0.00 C +ATOM 1342 C ALA 142 -0.957 -7.870 -3.707 1.00 0.00 C +ATOM 1343 O ALA 142 -1.053 -8.636 -4.673 1.00 0.00 O +ATOM 1344 N ILE 143 -0.772 -6.544 -3.821 1.00 0.00 N +ATOM 1345 H ILE 143 -0.719 -6.012 -2.993 1.00 0.00 H +ATOM 1346 CA ILE 143 -0.629 -5.807 -5.102 1.00 0.00 C +ATOM 1347 CB ILE 143 -0.856 -4.251 -4.872 1.00 0.00 C +ATOM 1348 CG2 ILE 143 -0.347 -3.409 -6.071 1.00 0.00 C +ATOM 1349 CG1 ILE 143 -2.339 -3.979 -4.569 1.00 0.00 C +ATOM 1350 CD1 ILE 143 -2.606 -2.825 -3.600 1.00 0.00 C +ATOM 1351 C ILE 143 0.686 -6.028 -5.892 1.00 0.00 C +ATOM 1352 O ILE 143 0.637 -6.323 -7.090 1.00 0.00 O +ATOM 1353 N PHE 144 1.833 -5.901 -5.210 1.00 0.00 N +ATOM 1354 H PHE 144 1.808 -5.719 -4.248 1.00 0.00 H +ATOM 1355 CA PHE 144 3.171 -6.027 -5.818 1.00 0.00 C +ATOM 1356 CB PHE 144 4.234 -5.307 -4.927 1.00 0.00 C +ATOM 1357 CG PHE 144 5.070 -6.220 -4.039 1.00 0.00 C +ATOM 1358 CD1 PHE 144 4.510 -6.884 -2.926 1.00 0.00 C +ATOM 1359 CD2 PHE 144 6.432 -6.422 -4.329 1.00 0.00 C +ATOM 1360 CE1 PHE 144 5.293 -7.738 -2.121 1.00 0.00 C +ATOM 1361 CE2 PHE 144 7.226 -7.273 -3.534 1.00 0.00 C +ATOM 1362 CZ PHE 144 6.655 -7.931 -2.432 1.00 0.00 C +ATOM 1363 C PHE 144 3.640 -7.423 -6.291 1.00 0.00 C +ATOM 1364 O PHE 144 4.322 -7.525 -7.314 1.00 0.00 O +ATOM 1365 N ASP 145 3.265 -8.469 -5.538 1.00 0.00 N +ATOM 1366 H ASP 145 2.703 -8.301 -4.749 1.00 0.00 H +ATOM 1367 CA ASP 145 3.625 -9.890 -5.784 1.00 0.00 C +ATOM 1368 CB ASP 145 2.914 -10.807 -4.755 1.00 0.00 C +ATOM 1369 CG ASP 145 1.391 -10.592 -4.684 1.00 0.00 C +ATOM 1370 OD1 ASP 145 0.831 -10.776 -3.584 1.00 0.00 O +ATOM 1371 OD2 ASP 145 0.755 -10.267 -5.713 1.00 0.00 O +ATOM 1372 C ASP 145 3.505 -10.480 -7.215 1.00 0.00 C +ATOM 1373 O ASP 145 4.012 -11.578 -7.480 1.00 0.00 O +ATOM 1374 N GLY 146 2.853 -9.741 -8.118 1.00 0.00 N +ATOM 1375 H GLY 146 2.461 -8.874 -7.876 1.00 0.00 H +ATOM 1376 CA GLY 146 2.683 -10.177 -9.501 1.00 0.00 C +ATOM 1377 C GLY 146 3.411 -9.252 -10.464 1.00 0.00 C +ATOM 1378 O GLY 146 2.782 -8.652 -11.344 1.00 0.00 O +ATOM 1379 N LEU 147 4.735 -9.155 -10.290 1.00 0.00 N +ATOM 1380 H LEU 147 5.158 -9.685 -9.581 1.00 0.00 H +ATOM 1381 CA LEU 147 5.622 -8.299 -11.095 1.00 0.00 C +ATOM 1382 CB LEU 147 6.553 -7.485 -10.139 1.00 0.00 C +ATOM 1383 CG LEU 147 7.587 -6.339 -10.365 1.00 0.00 C +ATOM 1384 CD1 LEU 147 8.946 -6.877 -10.820 1.00 0.00 C +ATOM 1385 CD2 LEU 147 7.082 -5.237 -11.302 1.00 0.00 C +ATOM 1386 C LEU 147 6.443 -9.081 -12.145 1.00 0.00 C +ATOM 1387 O LEU 147 6.400 -10.315 -12.179 1.00 0.00 O +ATOM 1388 N THR 148 7.118 -8.333 -13.034 1.00 0.00 N +ATOM 1389 H THR 148 7.053 -7.353 -12.999 1.00 0.00 H +ATOM 1390 CA THR 148 7.988 -8.855 -14.108 1.00 0.00 C +ATOM 1391 CB THR 148 7.223 -9.013 -15.472 1.00 0.00 C +ATOM 1392 OG1 THR 148 5.843 -9.305 -15.214 1.00 0.00 O +ATOM 1393 HG1 THR 148 5.756 -10.146 -14.758 1.00 0.00 H +ATOM 1394 CG2 THR 148 7.809 -10.164 -16.304 1.00 0.00 C +ATOM 1395 C THR 148 9.133 -7.830 -14.272 1.00 0.00 C +ATOM 1396 O THR 148 8.913 -6.621 -14.106 1.00 0.00 O +ATOM 1397 N ASP 149 10.344 -8.329 -14.560 1.00 0.00 N +ATOM 1398 H ASP 149 10.470 -9.298 -14.655 1.00 0.00 H +ATOM 1399 CA ASP 149 11.553 -7.506 -14.754 1.00 0.00 C +ATOM 1400 CB ASP 149 12.713 -8.079 -13.905 1.00 0.00 C +ATOM 1401 CG ASP 149 13.747 -7.022 -13.508 1.00 0.00 C +ATOM 1402 OD1 ASP 149 13.575 -6.381 -12.448 1.00 0.00 O +ATOM 1403 OD2 ASP 149 14.739 -6.847 -14.249 1.00 0.00 O +ATOM 1404 C ASP 149 11.903 -7.483 -16.263 1.00 0.00 C +ATOM 1405 O ASP 149 11.103 -7.955 -17.081 1.00 0.00 O +ATOM 1406 N LYS 150 13.080 -6.939 -16.617 1.00 0.00 N +ATOM 1407 H LYS 150 13.668 -6.578 -15.920 1.00 0.00 H +ATOM 1408 CA LYS 150 13.568 -6.835 -18.012 1.00 0.00 C +ATOM 1409 CB LYS 150 14.853 -5.997 -18.075 1.00 0.00 C +ATOM 1410 CG LYS 150 14.664 -4.514 -17.773 1.00 0.00 C +ATOM 1411 CD LYS 150 15.982 -3.761 -17.857 1.00 0.00 C +ATOM 1412 CE LYS 150 15.794 -2.283 -17.556 1.00 0.00 C +ATOM 1413 NZ LYS 150 17.077 -1.532 -17.635 1.00 0.00 N +ATOM 1414 HZ1 LYS 150 16.905 -0.529 -17.422 1.00 0.00 H +ATOM 1415 HZ2 LYS 150 17.472 -1.621 -18.593 1.00 0.00 H +ATOM 1416 HZ3 LYS 150 17.750 -1.922 -16.944 1.00 0.00 H +ATOM 1417 C LYS 150 13.809 -8.206 -18.672 1.00 0.00 C +ATOM 1418 O LYS 150 13.558 -8.370 -19.872 1.00 0.00 O +ATOM 1419 N LYS 151 14.292 -9.167 -17.872 1.00 0.00 N +ATOM 1420 H LYS 151 14.486 -8.976 -16.928 1.00 0.00 H +ATOM 1421 CA LYS 151 14.570 -10.550 -18.305 1.00 0.00 C +ATOM 1422 CB LYS 151 16.080 -10.860 -18.259 1.00 0.00 C +ATOM 1423 CG LYS 151 16.917 -10.106 -19.287 1.00 0.00 C +ATOM 1424 CD LYS 151 18.394 -10.470 -19.174 1.00 0.00 C +ATOM 1425 CE LYS 151 19.252 -9.726 -20.195 1.00 0.00 C +ATOM 1426 NZ LYS 151 19.350 -8.258 -19.936 1.00 0.00 N +ATOM 1427 HZ1 LYS 151 19.945 -7.817 -20.666 1.00 0.00 H +ATOM 1428 HZ2 LYS 151 18.399 -7.837 -19.964 1.00 0.00 H +ATOM 1429 HZ3 LYS 151 19.773 -8.099 -19.000 1.00 0.00 H +ATOM 1430 C LYS 151 13.798 -11.519 -17.395 1.00 0.00 C +ATOM 1431 O LYS 151 13.972 -11.491 -16.169 1.00 0.00 O +ATOM 1432 N THR 152 12.944 -12.359 -18.012 1.00 0.00 N +ATOM 1433 H THR 152 12.863 -12.320 -18.991 1.00 0.00 H +ATOM 1434 CA THR 152 12.064 -13.391 -17.383 1.00 0.00 C +ATOM 1435 CB THR 152 12.742 -14.843 -17.348 1.00 0.00 C +ATOM 1436 OG1 THR 152 11.823 -15.803 -16.810 1.00 0.00 O +ATOM 1437 HG1 THR 152 11.043 -15.863 -17.368 1.00 0.00 H +ATOM 1438 CG2 THR 152 14.052 -14.868 -16.532 1.00 0.00 C +ATOM 1439 C THR 152 11.335 -13.062 -16.051 1.00 0.00 C +ATOM 1440 O THR 152 11.925 -12.470 -15.141 1.00 0.00 O +ATOM 1441 N GLY 153 10.066 -13.480 -15.954 1.00 0.00 N +ATOM 1442 H GLY 153 9.637 -13.964 -16.693 1.00 0.00 H +ATOM 1443 CA GLY 153 9.248 -13.247 -14.765 1.00 0.00 C +ATOM 1444 C GLY 153 9.491 -14.247 -13.641 1.00 0.00 C +ATOM 1445 O GLY 153 9.301 -15.453 -13.838 1.00 0.00 O +ATOM 1446 N ARG 154 9.906 -13.735 -12.476 1.00 0.00 N +ATOM 1447 H ARG 154 10.017 -12.764 -12.398 1.00 0.00 H +ATOM 1448 CA ARG 154 10.211 -14.548 -11.287 1.00 0.00 C +ATOM 1449 CB ARG 154 11.532 -14.096 -10.642 1.00 0.00 C +ATOM 1450 CG ARG 154 12.781 -14.356 -11.489 1.00 0.00 C +ATOM 1451 CD ARG 154 14.052 -13.824 -10.828 1.00 0.00 C +ATOM 1452 NE ARG 154 14.107 -12.359 -10.794 1.00 0.00 N +ATOM 1453 HE ARG 154 13.355 -11.865 -11.182 1.00 0.00 H +ATOM 1454 CZ ARG 154 15.103 -11.640 -10.275 1.00 0.00 C +ATOM 1455 NH1 ARG 154 15.037 -10.316 -10.305 1.00 0.00 N +ATOM 1456 HH11 ARG 154 14.245 -9.864 -10.714 1.00 0.00 H +ATOM 1457 HH12 ARG 154 15.780 -9.769 -9.918 1.00 0.00 H +ATOM 1458 NH2 ARG 154 16.164 -12.226 -9.728 1.00 0.00 N +ATOM 1459 HH21 ARG 154 16.225 -13.224 -9.700 1.00 0.00 H +ATOM 1460 HH22 ARG 154 16.900 -11.669 -9.344 1.00 0.00 H +ATOM 1461 C ARG 154 9.091 -14.653 -10.213 1.00 0.00 C +ATOM 1462 O ARG 154 8.865 -15.762 -9.715 1.00 0.00 O +ATOM 1463 N PRO 155 8.390 -13.533 -9.821 1.00 0.00 N +ATOM 1464 CD PRO 155 7.239 -13.879 -8.955 1.00 0.00 C +ATOM 1465 CA PRO 155 8.347 -12.079 -10.123 1.00 0.00 C +ATOM 1466 CB PRO 155 7.066 -11.617 -9.406 1.00 0.00 C +ATOM 1467 CG PRO 155 6.924 -12.581 -8.269 1.00 0.00 C +ATOM 1468 C PRO 155 9.602 -11.253 -9.722 1.00 0.00 C +ATOM 1469 O PRO 155 10.475 -11.024 -10.568 1.00 0.00 O +ATOM 1470 N LEU 156 9.672 -10.816 -8.454 1.00 0.00 N +ATOM 1471 H LEU 156 8.950 -11.009 -7.818 1.00 0.00 H +ATOM 1472 CA LEU 156 10.801 -10.040 -7.915 1.00 0.00 C +ATOM 1473 CB LEU 156 10.466 -8.514 -7.837 1.00 0.00 C +ATOM 1474 CG LEU 156 9.526 -7.585 -7.020 1.00 0.00 C +ATOM 1475 CD1 LEU 156 8.087 -8.082 -6.957 1.00 0.00 C +ATOM 1476 CD2 LEU 156 10.086 -7.327 -5.624 1.00 0.00 C +ATOM 1477 C LEU 156 11.259 -10.614 -6.562 1.00 0.00 C +ATOM 1478 O LEU 156 12.445 -10.519 -6.220 1.00 0.00 O +ATOM 1479 N ILE 157 10.312 -11.201 -5.812 1.00 0.00 N +ATOM 1480 H ILE 157 9.381 -11.231 -6.125 1.00 0.00 H +ATOM 1481 CA ILE 157 10.569 -11.834 -4.501 1.00 0.00 C +ATOM 1482 CB ILE 157 9.669 -11.206 -3.312 1.00 0.00 C +ATOM 1483 CG2 ILE 157 10.135 -9.781 -2.994 1.00 0.00 C +ATOM 1484 CG1 ILE 157 8.128 -11.377 -3.495 1.00 0.00 C +ATOM 1485 CD1 ILE 157 7.393 -10.686 -4.687 1.00 0.00 C +ATOM 1486 C ILE 157 10.403 -13.371 -4.620 1.00 0.00 C +ATOM 1487 O ILE 157 9.375 -13.841 -5.124 1.00 0.00 O +ATOM 1488 N GLU 158 11.444 -14.128 -4.242 1.00 0.00 N +ATOM 1489 H GLU 158 12.266 -13.707 -3.906 1.00 0.00 H +ATOM 1490 CA GLU 158 11.441 -15.607 -4.296 1.00 0.00 C +ATOM 1491 CB GLU 158 12.382 -16.134 -5.396 1.00 0.00 C +ATOM 1492 CG GLU 158 11.923 -15.860 -6.825 1.00 0.00 C +ATOM 1493 CD GLU 158 12.859 -16.452 -7.863 1.00 0.00 C +ATOM 1494 OE1 GLU 158 13.833 -15.770 -8.247 1.00 0.00 O +ATOM 1495 OE2 GLU 158 12.620 -17.599 -8.294 1.00 0.00 O +ATOM 1496 C GLU 158 11.807 -16.245 -2.951 1.00 0.00 C +ATOM 1497 O GLU 158 11.034 -17.052 -2.422 1.00 0.00 O +ATOM 1498 N GLY 159 12.978 -15.881 -2.412 1.00 0.00 N +ATOM 1499 H GLY 159 13.566 -15.240 -2.868 1.00 0.00 H +ATOM 1500 CA GLY 159 13.451 -16.403 -1.132 1.00 0.00 C +ATOM 1501 C GLY 159 13.072 -15.486 0.016 1.00 0.00 C +ATOM 1502 O GLY 159 13.584 -15.625 1.134 1.00 0.00 O +ATOM 1503 N LYS 160 12.166 -14.551 -0.290 1.00 0.00 N +ATOM 1504 H LYS 160 11.814 -14.510 -1.205 1.00 0.00 H +ATOM 1505 CA LYS 160 11.641 -13.556 0.651 1.00 0.00 C +ATOM 1506 CB LYS 160 11.726 -12.145 0.053 1.00 0.00 C +ATOM 1507 CG LYS 160 13.142 -11.671 -0.278 1.00 0.00 C +ATOM 1508 CD LYS 160 13.136 -10.268 -0.876 1.00 0.00 C +ATOM 1509 CE LYS 160 14.501 -9.870 -1.436 1.00 0.00 C +ATOM 1510 NZ LYS 160 15.558 -9.698 -0.397 1.00 0.00 N +ATOM 1511 HZ1 LYS 160 16.452 -9.429 -0.854 1.00 0.00 H +ATOM 1512 HZ2 LYS 160 15.271 -8.953 0.269 1.00 0.00 H +ATOM 1513 HZ3 LYS 160 15.687 -10.593 0.117 1.00 0.00 H +ATOM 1514 C LYS 160 10.177 -13.888 0.954 1.00 0.00 C +ATOM 1515 O LYS 160 9.476 -14.434 0.091 1.00 0.00 O +ATOM 1516 N SER 161 9.735 -13.570 2.176 1.00 0.00 N +ATOM 1517 H SER 161 10.328 -13.137 2.822 1.00 0.00 H +ATOM 1518 CA SER 161 8.358 -13.814 2.625 1.00 0.00 C +ATOM 1519 CB SER 161 8.345 -14.504 3.996 1.00 0.00 C +ATOM 1520 OG SER 161 9.016 -15.752 3.949 1.00 0.00 O +ATOM 1521 HG SER 161 9.945 -15.629 3.739 1.00 0.00 H +ATOM 1522 C SER 161 7.561 -12.511 2.699 1.00 0.00 C +ATOM 1523 O SER 161 8.030 -11.527 3.289 1.00 0.00 O +ATOM 1524 N ILE 162 6.397 -12.491 2.034 1.00 0.00 N +ATOM 1525 H ILE 162 6.100 -13.270 1.514 1.00 0.00 H +ATOM 1526 CA ILE 162 5.494 -11.328 2.029 1.00 0.00 C +ATOM 1527 CB ILE 162 5.384 -10.607 0.613 1.00 0.00 C +ATOM 1528 CG2 ILE 162 6.745 -10.097 0.205 1.00 0.00 C +ATOM 1529 CG1 ILE 162 4.854 -11.527 -0.503 1.00 0.00 C +ATOM 1530 CD1 ILE 162 3.484 -11.139 -1.062 1.00 0.00 C +ATOM 1531 C ILE 162 4.135 -11.741 2.613 1.00 0.00 C +ATOM 1532 O ILE 162 3.533 -12.728 2.168 1.00 0.00 O +ATOM 1533 N THR 163 3.686 -10.993 3.628 1.00 0.00 N +ATOM 1534 H THR 163 4.194 -10.212 3.941 1.00 0.00 H +ATOM 1535 CA THR 163 2.431 -11.264 4.344 1.00 0.00 C +ATOM 1536 CB THR 163 2.697 -11.610 5.850 1.00 0.00 C +ATOM 1537 OG1 THR 163 3.333 -10.498 6.492 1.00 0.00 O +ATOM 1538 HG1 THR 163 3.496 -10.711 7.414 1.00 0.00 H +ATOM 1539 CG2 THR 163 3.608 -12.824 5.970 1.00 0.00 C +ATOM 1540 C THR 163 1.401 -10.131 4.243 1.00 0.00 C +ATOM 1541 O THR 163 1.762 -8.947 4.214 1.00 0.00 O +ATOM 1542 N GLY 164 0.128 -10.527 4.153 1.00 0.00 N +ATOM 1543 H GLY 164 -0.103 -11.473 4.193 1.00 0.00 H +ATOM 1544 CA GLY 164 -0.993 -9.603 4.070 1.00 0.00 C +ATOM 1545 C GLY 164 -1.877 -9.870 5.272 1.00 0.00 C +ATOM 1546 O GLY 164 -2.089 -11.040 5.618 1.00 0.00 O +ATOM 1547 N PHE 165 -2.364 -8.801 5.916 1.00 0.00 N +ATOM 1548 H PHE 165 -2.159 -7.905 5.576 1.00 0.00 H +ATOM 1549 CA PHE 165 -3.202 -8.911 7.120 1.00 0.00 C +ATOM 1550 CB PHE 165 -2.415 -8.403 8.363 1.00 0.00 C +ATOM 1551 CG PHE 165 -1.046 -9.048 8.553 1.00 0.00 C +ATOM 1552 CD1 PHE 165 0.126 -8.371 8.155 1.00 0.00 C +ATOM 1553 CD2 PHE 165 -0.919 -10.335 9.121 1.00 0.00 C +ATOM 1554 CE1 PHE 165 1.397 -8.970 8.316 1.00 0.00 C +ATOM 1555 CE2 PHE 165 0.343 -10.940 9.284 1.00 0.00 C +ATOM 1556 CZ PHE 165 1.503 -10.259 8.882 1.00 0.00 C +ATOM 1557 C PHE 165 -4.625 -8.311 7.025 1.00 0.00 C +ATOM 1558 O PHE 165 -5.462 -8.872 6.315 1.00 0.00 O +ATOM 1559 N THR 166 -4.905 -7.201 7.731 1.00 0.00 N +ATOM 1560 H THR 166 -4.213 -6.796 8.291 1.00 0.00 H +ATOM 1561 CA THR 166 -6.228 -6.533 7.734 1.00 0.00 C +ATOM 1562 CB THR 166 -6.351 -5.517 8.917 1.00 0.00 C +ATOM 1563 OG1 THR 166 -5.577 -5.984 10.028 1.00 0.00 O +ATOM 1564 HG1 THR 166 -5.938 -6.807 10.365 1.00 0.00 H +ATOM 1565 CG2 THR 166 -7.811 -5.379 9.381 1.00 0.00 C +ATOM 1566 C THR 166 -6.494 -5.837 6.381 1.00 0.00 C +ATOM 1567 O THR 166 -5.541 -5.489 5.671 1.00 0.00 O +ATOM 1568 N ASP 167 -7.787 -5.687 6.031 1.00 0.00 N +ATOM 1569 H ASP 167 -8.485 -5.993 6.651 1.00 0.00 H +ATOM 1570 CA ASP 167 -8.323 -5.089 4.773 1.00 0.00 C +ATOM 1571 CB ASP 167 -7.696 -3.714 4.431 1.00 0.00 C +ATOM 1572 CG ASP 167 -7.992 -2.649 5.481 1.00 0.00 C +ATOM 1573 OD1 ASP 167 -7.193 -2.505 6.432 1.00 0.00 O +ATOM 1574 OD2 ASP 167 -9.016 -1.943 5.347 1.00 0.00 O +ATOM 1575 C ASP 167 -8.197 -6.066 3.586 1.00 0.00 C +ATOM 1576 O ASP 167 -8.950 -5.971 2.607 1.00 0.00 O +ATOM 1577 N VAL 168 -7.251 -7.010 3.717 1.00 0.00 N +ATOM 1578 H VAL 168 -6.674 -7.058 4.501 1.00 0.00 H +ATOM 1579 CA VAL 168 -6.952 -8.072 2.740 1.00 0.00 C +ATOM 1580 CB VAL 168 -5.419 -8.009 2.267 1.00 0.00 C +ATOM 1581 CG1 VAL 168 -4.436 -8.219 3.426 1.00 0.00 C +ATOM 1582 CG2 VAL 168 -5.146 -8.970 1.098 1.00 0.00 C +ATOM 1583 C VAL 168 -7.353 -9.426 3.388 1.00 0.00 C +ATOM 1584 O VAL 168 -7.488 -10.444 2.698 1.00 0.00 O +ATOM 1585 N GLY 169 -7.557 -9.393 4.713 1.00 0.00 N +ATOM 1586 H GLY 169 -7.450 -8.556 5.216 1.00 0.00 H +ATOM 1587 CA GLY 169 -7.945 -10.562 5.500 1.00 0.00 C +ATOM 1588 C GLY 169 -9.349 -11.090 5.235 1.00 0.00 C +ATOM 1589 O GLY 169 -9.557 -12.308 5.198 1.00 0.00 O +ATOM 1590 N GLU 170 -10.294 -10.165 5.015 1.00 0.00 N +ATOM 1591 H GLU 170 -10.031 -9.220 5.039 1.00 0.00 H +ATOM 1592 CA GLU 170 -11.710 -10.472 4.735 1.00 0.00 C +ATOM 1593 CB GLU 170 -12.564 -9.198 4.785 1.00 0.00 C +ATOM 1594 CG GLU 170 -12.727 -8.592 6.177 1.00 0.00 C +ATOM 1595 CD GLU 170 -13.581 -7.338 6.175 1.00 0.00 C +ATOM 1596 OE1 GLU 170 -14.816 -7.456 6.330 1.00 0.00 O +ATOM 1597 OE2 GLU 170 -13.019 -6.234 6.022 1.00 0.00 O +ATOM 1598 C GLU 170 -11.883 -11.166 3.373 1.00 0.00 C +ATOM 1599 O GLU 170 -12.724 -12.063 3.235 1.00 0.00 O +ATOM 1600 N THR 171 -11.082 -10.734 2.386 1.00 0.00 N +ATOM 1601 H THR 171 -10.450 -10.004 2.580 1.00 0.00 H +ATOM 1602 CA THR 171 -11.070 -11.284 1.013 1.00 0.00 C +ATOM 1603 CB THR 171 -10.299 -10.356 0.021 1.00 0.00 C +ATOM 1604 OG1 THR 171 -9.002 -10.051 0.549 1.00 0.00 O +ATOM 1605 HG1 THR 171 -8.532 -9.481 -0.064 1.00 0.00 H +ATOM 1606 CG2 THR 171 -11.066 -9.062 -0.220 1.00 0.00 C +ATOM 1607 C THR 171 -10.487 -12.714 0.954 1.00 0.00 C +ATOM 1608 O THR 171 -11.069 -13.593 0.308 1.00 0.00 O +ATOM 1609 N ILE 172 -9.372 -12.931 1.673 1.00 0.00 N +ATOM 1610 H ILE 172 -9.002 -12.188 2.201 1.00 0.00 H +ATOM 1611 CA ILE 172 -8.651 -14.220 1.748 1.00 0.00 C +ATOM 1612 CB ILE 172 -7.147 -14.010 2.275 1.00 0.00 C +ATOM 1613 CG2 ILE 172 -7.112 -13.582 3.755 1.00 0.00 C +ATOM 1614 CG1 ILE 172 -6.194 -15.174 1.873 1.00 0.00 C +ATOM 1615 CD1 ILE 172 -6.153 -16.490 2.750 1.00 0.00 C +ATOM 1616 C ILE 172 -9.431 -15.337 2.499 1.00 0.00 C +ATOM 1617 O ILE 172 -9.324 -16.513 2.130 1.00 0.00 O +ATOM 1618 N LEU 173 -10.172 -14.958 3.553 1.00 0.00 N +ATOM 1619 H LEU 173 -10.175 -14.011 3.830 1.00 0.00 H +ATOM 1620 CA LEU 173 -10.990 -15.887 4.365 1.00 0.00 C +ATOM 1621 CB LEU 173 -11.659 -15.157 5.547 1.00 0.00 C +ATOM 1622 CG LEU 173 -10.898 -14.801 6.837 1.00 0.00 C +ATOM 1623 CD1 LEU 173 -11.497 -13.529 7.412 1.00 0.00 C +ATOM 1624 CD2 LEU 173 -10.933 -15.928 7.888 1.00 0.00 C +ATOM 1625 C LEU 173 -12.059 -16.607 3.531 1.00 0.00 C +ATOM 1626 O LEU 173 -12.367 -17.776 3.786 1.00 0.00 O +ATOM 1627 N GLY 174 -12.609 -15.889 2.548 1.00 0.00 N +ATOM 1628 H GLY 174 -12.344 -14.957 2.383 1.00 0.00 H +ATOM 1629 CA GLY 174 -13.629 -16.439 1.667 1.00 0.00 C +ATOM 1630 C GLY 174 -13.353 -16.187 0.193 1.00 0.00 C +ATOM 1631 O GLY 174 -13.991 -15.319 -0.411 1.00 0.00 O +ATOM 1632 N VAL 175 -12.418 -16.959 -0.381 1.00 0.00 N +ATOM 1633 H VAL 175 -11.967 -17.629 0.176 1.00 0.00 H +ATOM 1634 CA VAL 175 -12.026 -16.869 -1.805 1.00 0.00 C +ATOM 1635 CB VAL 175 -10.526 -17.326 -2.039 1.00 0.00 C +ATOM 1636 CG1 VAL 175 -10.032 -16.923 -3.439 1.00 0.00 C +ATOM 1637 CG2 VAL 175 -9.603 -16.734 -0.982 1.00 0.00 C +ATOM 1638 C VAL 175 -12.998 -17.772 -2.603 1.00 0.00 C +ATOM 1639 O VAL 175 -13.479 -18.777 -2.065 1.00 0.00 O +ATOM 1640 N ASP 176 -13.291 -17.396 -3.857 1.00 0.00 N +ATOM 1641 H ASP 176 -12.880 -16.588 -4.235 1.00 0.00 H +ATOM 1642 CA ASP 176 -14.216 -18.143 -4.736 1.00 0.00 C +ATOM 1643 CB ASP 176 -14.667 -17.267 -5.930 1.00 0.00 C +ATOM 1644 CG ASP 176 -13.501 -16.586 -6.661 1.00 0.00 C +ATOM 1645 OD1 ASP 176 -12.964 -17.183 -7.620 1.00 0.00 O +ATOM 1646 OD2 ASP 176 -13.137 -15.451 -6.283 1.00 0.00 O +ATOM 1647 C ASP 176 -13.748 -19.535 -5.220 1.00 0.00 C +ATOM 1648 O ASP 176 -14.521 -20.496 -5.148 1.00 0.00 O +ATOM 1649 N SER 177 -12.517 -19.621 -5.745 1.00 0.00 N +ATOM 1650 H SER 177 -11.962 -18.814 -5.821 1.00 0.00 H +ATOM 1651 CA SER 177 -11.925 -20.887 -6.224 1.00 0.00 C +ATOM 1652 CB SER 177 -10.769 -20.592 -7.195 1.00 0.00 C +ATOM 1653 OG SER 177 -10.313 -21.767 -7.848 1.00 0.00 O +ATOM 1654 HG SER 177 -9.959 -22.391 -7.209 1.00 0.00 H +ATOM 1655 C SER 177 -11.462 -21.849 -5.103 1.00 0.00 C +ATOM 1656 O SER 177 -11.821 -23.032 -5.113 1.00 0.00 O +ATOM 1657 N ILE 178 -10.672 -21.316 -4.158 1.00 0.00 N +ATOM 1658 H ILE 178 -10.452 -20.358 -4.216 1.00 0.00 H +ATOM 1659 CA ILE 178 -10.100 -22.049 -3.003 1.00 0.00 C +ATOM 1660 CB ILE 178 -8.808 -21.321 -2.432 1.00 0.00 C +ATOM 1661 CG2 ILE 178 -7.953 -22.303 -1.579 1.00 0.00 C +ATOM 1662 CG1 ILE 178 -7.922 -20.807 -3.582 1.00 0.00 C +ATOM 1663 CD1 ILE 178 -7.328 -19.409 -3.366 1.00 0.00 C +ATOM 1664 C ILE 178 -11.072 -22.412 -1.847 1.00 0.00 C +ATOM 1665 O ILE 178 -11.075 -23.562 -1.388 1.00 0.00 O +ATOM 1666 N LEU 179 -11.881 -21.438 -1.403 1.00 0.00 N +ATOM 1667 H LEU 179 -11.868 -20.554 -1.831 1.00 0.00 H +ATOM 1668 CA LEU 179 -12.825 -21.603 -0.280 1.00 0.00 C +ATOM 1669 CB LEU 179 -12.598 -20.476 0.771 1.00 0.00 C +ATOM 1670 CG LEU 179 -11.362 -20.179 1.671 1.00 0.00 C +ATOM 1671 CD1 LEU 179 -11.110 -21.277 2.719 1.00 0.00 C +ATOM 1672 CD2 LEU 179 -10.083 -19.867 0.874 1.00 0.00 C +ATOM 1673 C LEU 179 -14.318 -21.681 -0.639 1.00 0.00 C +ATOM 1674 O LEU 179 -15.100 -22.275 0.115 1.00 0.00 O +ATOM 1675 N LYS 180 -14.699 -21.104 -1.792 1.00 0.00 N +ATOM 1676 H LYS 180 -14.023 -20.684 -2.366 1.00 0.00 H +ATOM 1677 CA LYS 180 -16.091 -21.040 -2.324 1.00 0.00 C +ATOM 1678 CB LYS 180 -16.640 -22.436 -2.716 1.00 0.00 C +ATOM 1679 CG LYS 180 -15.918 -23.107 -3.879 1.00 0.00 C +ATOM 1680 CD LYS 180 -16.523 -24.471 -4.193 1.00 0.00 C +ATOM 1681 CE LYS 180 -15.814 -25.163 -5.356 1.00 0.00 C +ATOM 1682 NZ LYS 180 -14.419 -25.591 -5.035 1.00 0.00 N +ATOM 1683 HZ1 LYS 180 -13.999 -26.053 -5.867 1.00 0.00 H +ATOM 1684 HZ2 LYS 180 -14.437 -26.261 -4.240 1.00 0.00 H +ATOM 1685 HZ3 LYS 180 -13.852 -24.759 -4.776 1.00 0.00 H +ATOM 1686 C LYS 180 -17.085 -20.276 -1.412 1.00 0.00 C +ATOM 1687 O LYS 180 -17.864 -20.886 -0.663 1.00 0.00 O +ATOM 1688 N ALA 181 -17.002 -18.938 -1.459 1.00 0.00 N +ATOM 1689 H ALA 181 -16.347 -18.501 -2.047 1.00 0.00 H +ATOM 1690 CA ALA 181 -17.847 -18.023 -0.670 1.00 0.00 C +ATOM 1691 CB ALA 181 -17.001 -17.322 0.412 1.00 0.00 C +ATOM 1692 C ALA 181 -18.532 -16.988 -1.584 1.00 0.00 C +ATOM 1693 O ALA 181 -18.628 -17.211 -2.797 1.00 0.00 O +ATOM 1694 N LYS 182 -18.998 -15.874 -0.997 1.00 0.00 N +ATOM 1695 H LYS 182 -18.895 -15.746 -0.029 1.00 0.00 H +ATOM 1696 CA LYS 182 -19.685 -14.778 -1.709 1.00 0.00 C +ATOM 1697 CB LYS 182 -20.781 -14.169 -0.823 1.00 0.00 C +ATOM 1698 CG LYS 182 -21.979 -15.079 -0.571 1.00 0.00 C +ATOM 1699 CD LYS 182 -23.016 -14.397 0.315 1.00 0.00 C +ATOM 1700 CE LYS 182 -24.225 -15.292 0.581 1.00 0.00 C +ATOM 1701 NZ LYS 182 -23.918 -16.472 1.443 1.00 0.00 N +ATOM 1702 HZ1 LYS 182 -23.193 -17.059 0.982 1.00 0.00 H +ATOM 1703 HZ2 LYS 182 -24.781 -17.035 1.582 1.00 0.00 H +ATOM 1704 HZ3 LYS 182 -23.564 -16.146 2.365 1.00 0.00 H +ATOM 1705 C LYS 182 -18.732 -13.668 -2.192 1.00 0.00 C +ATOM 1706 O LYS 182 -19.003 -13.023 -3.213 1.00 0.00 O +ATOM 1707 N ASN 183 -17.622 -13.473 -1.465 1.00 0.00 N +ATOM 1708 H ASN 183 -17.447 -14.021 -0.669 1.00 0.00 H +ATOM 1709 CA ASN 183 -16.598 -12.456 -1.782 1.00 0.00 C +ATOM 1710 CB ASN 183 -16.084 -11.760 -0.498 1.00 0.00 C +ATOM 1711 CG ASN 183 -15.701 -12.739 0.618 1.00 0.00 C +ATOM 1712 OD1 ASN 183 -14.525 -13.053 0.802 1.00 0.00 O +ATOM 1713 ND2 ASN 183 -16.693 -13.198 1.378 1.00 0.00 N +ATOM 1714 HD21 ASN 183 -16.463 -13.825 2.096 1.00 0.00 H +ATOM 1715 HD22 ASN 183 -17.609 -12.898 1.198 1.00 0.00 H +ATOM 1716 C ASN 183 -15.435 -12.982 -2.653 1.00 0.00 C +ATOM 1717 O ASN 183 -15.099 -14.170 -2.585 1.00 0.00 O +ATOM 1718 N LEU 184 -14.847 -12.087 -3.460 1.00 0.00 N +ATOM 1719 H LEU 184 -15.155 -11.156 -3.470 1.00 0.00 H +ATOM 1720 CA LEU 184 -13.738 -12.398 -4.384 1.00 0.00 C +ATOM 1721 CB LEU 184 -13.949 -11.677 -5.729 1.00 0.00 C +ATOM 1722 CG LEU 184 -15.093 -12.063 -6.687 1.00 0.00 C +ATOM 1723 CD1 LEU 184 -15.760 -10.799 -7.210 1.00 0.00 C +ATOM 1724 CD2 LEU 184 -14.596 -12.930 -7.855 1.00 0.00 C +ATOM 1725 C LEU 184 -12.334 -12.069 -3.854 1.00 0.00 C +ATOM 1726 O LEU 184 -12.158 -11.088 -3.119 1.00 0.00 O +ATOM 1727 N ALA 185 -11.355 -12.908 -4.229 1.00 0.00 N +ATOM 1728 H ALA 185 -11.559 -13.683 -4.797 1.00 0.00 H +ATOM 1729 CA ALA 185 -9.933 -12.771 -3.849 1.00 0.00 C +ATOM 1730 CB ALA 185 -9.663 -13.406 -2.476 1.00 0.00 C +ATOM 1731 C ALA 185 -9.015 -13.406 -4.905 1.00 0.00 C +ATOM 1732 O ALA 185 -9.272 -14.526 -5.363 1.00 0.00 O +ATOM 1733 N THR 186 -7.974 -12.659 -5.300 1.00 0.00 N +ATOM 1734 H THR 186 -7.842 -11.759 -4.928 1.00 0.00 H +ATOM 1735 CA THR 186 -6.957 -13.079 -6.289 1.00 0.00 C +ATOM 1736 CB THR 186 -7.048 -12.230 -7.608 1.00 0.00 C +ATOM 1737 OG1 THR 186 -7.091 -10.833 -7.287 1.00 0.00 O +ATOM 1738 HG1 THR 186 -6.280 -10.564 -6.847 1.00 0.00 H +ATOM 1739 CG2 THR 186 -8.288 -12.607 -8.409 1.00 0.00 C +ATOM 1740 C THR 186 -5.563 -12.906 -5.646 1.00 0.00 C +ATOM 1741 O THR 186 -4.535 -13.268 -6.241 1.00 0.00 O +ATOM 1742 N VAL 187 -5.569 -12.429 -4.393 1.00 0.00 N +ATOM 1743 H VAL 187 -6.441 -12.264 -3.966 1.00 0.00 H +ATOM 1744 CA VAL 187 -4.373 -12.139 -3.569 1.00 0.00 C +ATOM 1745 CB VAL 187 -4.755 -11.206 -2.340 1.00 0.00 C +ATOM 1746 CG1 VAL 187 -5.345 -9.891 -2.848 1.00 0.00 C +ATOM 1747 CG2 VAL 187 -5.775 -11.886 -1.397 1.00 0.00 C +ATOM 1748 C VAL 187 -3.511 -13.341 -3.101 1.00 0.00 C +ATOM 1749 O VAL 187 -2.282 -13.323 -3.264 1.00 0.00 O +ATOM 1750 N GLU 188 -4.168 -14.386 -2.576 1.00 0.00 N +ATOM 1751 H GLU 188 -5.149 -14.364 -2.519 1.00 0.00 H +ATOM 1752 CA GLU 188 -3.504 -15.602 -2.067 1.00 0.00 C +ATOM 1753 CB GLU 188 -4.491 -16.460 -1.244 1.00 0.00 C +ATOM 1754 CG GLU 188 -3.886 -17.296 -0.072 1.00 0.00 C +ATOM 1755 CD GLU 188 -3.387 -18.684 -0.475 1.00 0.00 C +ATOM 1756 OE1 GLU 188 -4.224 -19.586 -0.696 1.00 0.00 O +ATOM 1757 OE2 GLU 188 -2.154 -18.865 -0.558 1.00 0.00 O +ATOM 1758 C GLU 188 -2.852 -16.439 -3.183 1.00 0.00 C +ATOM 1759 O GLU 188 -1.707 -16.868 -3.028 1.00 0.00 O +ATOM 1760 N ASP 189 -3.564 -16.612 -4.308 1.00 0.00 N +ATOM 1761 H ASP 189 -4.458 -16.211 -4.383 1.00 0.00 H +ATOM 1762 CA ASP 189 -3.090 -17.385 -5.476 1.00 0.00 C +ATOM 1763 CB ASP 189 -4.226 -17.632 -6.497 1.00 0.00 C +ATOM 1764 CG ASP 189 -5.110 -16.404 -6.737 1.00 0.00 C +ATOM 1765 OD1 ASP 189 -4.778 -15.584 -7.621 1.00 0.00 O +ATOM 1766 OD2 ASP 189 -6.146 -16.277 -6.048 1.00 0.00 O +ATOM 1767 C ASP 189 -1.846 -16.785 -6.160 1.00 0.00 C +ATOM 1768 O ASP 189 -0.905 -17.521 -6.486 1.00 0.00 O +ATOM 1769 N VAL 190 -1.828 -15.449 -6.293 1.00 0.00 N +ATOM 1770 H VAL 190 -2.592 -14.925 -5.961 1.00 0.00 H +ATOM 1771 CA VAL 190 -0.714 -14.700 -6.908 1.00 0.00 C +ATOM 1772 CB VAL 190 -1.142 -13.209 -7.288 1.00 0.00 C +ATOM 1773 CG1 VAL 190 -1.489 -12.367 -6.057 1.00 0.00 C +ATOM 1774 CG2 VAL 190 -0.090 -12.524 -8.176 1.00 0.00 C +ATOM 1775 C VAL 190 0.556 -14.791 -6.018 1.00 0.00 C +ATOM 1776 O VAL 190 1.662 -14.967 -6.539 1.00 0.00 O +ATOM 1777 N ALA 191 0.371 -14.658 -4.696 1.00 0.00 N +ATOM 1778 H ALA 191 -0.530 -14.472 -4.334 1.00 0.00 H +ATOM 1779 CA ALA 191 1.455 -14.749 -3.699 1.00 0.00 C +ATOM 1780 CB ALA 191 1.017 -14.150 -2.376 1.00 0.00 C +ATOM 1781 C ALA 191 2.036 -16.164 -3.487 1.00 0.00 C +ATOM 1782 O ALA 191 3.261 -16.322 -3.431 1.00 0.00 O +ATOM 1783 N LYS 192 1.153 -17.171 -3.371 1.00 0.00 N +ATOM 1784 H LYS 192 0.194 -16.987 -3.437 1.00 0.00 H +ATOM 1785 CA LYS 192 1.523 -18.589 -3.156 1.00 0.00 C +ATOM 1786 CB LYS 192 0.347 -19.416 -2.579 1.00 0.00 C +ATOM 1787 CG LYS 192 -0.816 -19.768 -3.523 1.00 0.00 C +ATOM 1788 CD LYS 192 -1.647 -20.919 -2.961 1.00 0.00 C +ATOM 1789 CE LYS 192 -2.830 -21.272 -3.855 1.00 0.00 C +ATOM 1790 NZ LYS 192 -3.929 -20.265 -3.797 1.00 0.00 N +ATOM 1791 HZ1 LYS 192 -3.560 -19.338 -4.075 1.00 0.00 H +ATOM 1792 HZ2 LYS 192 -4.294 -20.210 -2.824 1.00 0.00 H +ATOM 1793 HZ3 LYS 192 -4.697 -20.546 -4.440 1.00 0.00 H +ATOM 1794 C LYS 192 2.223 -19.343 -4.311 1.00 0.00 C +ATOM 1795 O LYS 192 3.071 -20.203 -4.053 1.00 0.00 O +ATOM 1796 N LYS 193 1.866 -19.007 -5.561 1.00 0.00 N +ATOM 1797 H LYS 193 1.187 -18.301 -5.700 1.00 0.00 H +ATOM 1798 CA LYS 193 2.404 -19.650 -6.784 1.00 0.00 C +ATOM 1799 CB LYS 193 1.745 -19.066 -8.039 1.00 0.00 C +ATOM 1800 CG LYS 193 0.392 -19.676 -8.376 1.00 0.00 C +ATOM 1801 CD LYS 193 -0.201 -19.051 -9.628 1.00 0.00 C +ATOM 1802 CE LYS 193 -1.552 -19.662 -9.964 1.00 0.00 C +ATOM 1803 NZ LYS 193 -2.145 -19.058 -11.189 1.00 0.00 N +ATOM 1804 HZ1 LYS 193 -1.508 -19.214 -11.996 1.00 0.00 H +ATOM 1805 HZ2 LYS 193 -2.277 -18.037 -11.043 1.00 0.00 H +ATOM 1806 HZ3 LYS 193 -3.065 -19.502 -11.383 1.00 0.00 H +ATOM 1807 C LYS 193 3.934 -19.647 -6.957 1.00 0.00 C +ATOM 1808 O LYS 193 4.488 -20.628 -7.471 1.00 0.00 O +ATOM 1809 N TYR 194 4.604 -18.569 -6.525 1.00 0.00 N +ATOM 1810 H TYR 194 4.123 -17.810 -6.129 1.00 0.00 H +ATOM 1811 CA TYR 194 6.072 -18.450 -6.614 1.00 0.00 C +ATOM 1812 CB TYR 194 6.495 -17.003 -7.008 1.00 0.00 C +ATOM 1813 CG TYR 194 6.091 -15.854 -6.071 1.00 0.00 C +ATOM 1814 CD1 TYR 194 4.959 -15.051 -6.342 1.00 0.00 C +ATOM 1815 CE1 TYR 194 4.608 -13.970 -5.490 1.00 0.00 C +ATOM 1816 CD2 TYR 194 6.860 -15.546 -4.923 1.00 0.00 C +ATOM 1817 CE2 TYR 194 6.515 -14.481 -4.072 1.00 0.00 C +ATOM 1818 CZ TYR 194 5.393 -13.697 -4.358 1.00 0.00 C +ATOM 1819 OH TYR 194 5.069 -12.662 -3.515 1.00 0.00 O +ATOM 1820 HH TYR 194 5.696 -12.605 -2.789 1.00 0.00 H +ATOM 1821 C TYR 194 6.788 -18.921 -5.327 1.00 0.00 C +ATOM 1822 O TYR 194 7.756 -19.686 -5.397 1.00 0.00 O +ATOM 1823 N GLY 195 6.295 -18.451 -4.174 1.00 0.00 N +ATOM 1824 H GLY 195 5.522 -17.844 -4.163 1.00 0.00 H +ATOM 1825 CA GLY 195 6.863 -18.803 -2.878 1.00 0.00 C +ATOM 1826 C GLY 195 7.124 -17.614 -1.972 1.00 0.00 C +ATOM 1827 O GLY 195 8.176 -16.974 -2.090 1.00 0.00 O +ATOM 1828 N ALA 196 6.171 -17.323 -1.074 1.00 0.00 N +ATOM 1829 H ALA 196 5.365 -17.881 -1.044 1.00 0.00 H +ATOM 1830 CA ALA 196 6.261 -16.204 -0.119 1.00 0.00 C +ATOM 1831 CB ALA 196 5.557 -14.968 -0.672 1.00 0.00 C +ATOM 1832 C ALA 196 5.730 -16.527 1.285 1.00 0.00 C +ATOM 1833 O ALA 196 6.494 -16.449 2.251 1.00 0.00 O +ATOM 1834 N LYS 197 4.436 -16.894 1.386 1.00 0.00 N +ATOM 1835 H LYS 197 3.893 -16.947 0.569 1.00 0.00 H +ATOM 1836 CA LYS 197 3.698 -17.243 2.639 1.00 0.00 C +ATOM 1837 CB LYS 197 4.520 -18.143 3.589 1.00 0.00 C +ATOM 1838 CG LYS 197 4.750 -19.561 3.079 1.00 0.00 C +ATOM 1839 CD LYS 197 5.566 -20.381 4.073 1.00 0.00 C +ATOM 1840 CE LYS 197 5.809 -21.807 3.582 1.00 0.00 C +ATOM 1841 NZ LYS 197 6.723 -21.886 2.403 1.00 0.00 N +ATOM 1842 HZ1 LYS 197 6.314 -21.350 1.611 1.00 0.00 H +ATOM 1843 HZ2 LYS 197 7.648 -21.482 2.654 1.00 0.00 H +ATOM 1844 HZ3 LYS 197 6.843 -22.880 2.124 1.00 0.00 H +ATOM 1845 C LYS 197 3.119 -16.049 3.430 1.00 0.00 C +ATOM 1846 O LYS 197 3.754 -14.992 3.506 1.00 0.00 O +ATOM 1847 N TYR 198 1.927 -16.249 4.019 1.00 0.00 N +ATOM 1848 H TYR 198 1.473 -17.115 3.927 1.00 0.00 H +ATOM 1849 CA TYR 198 1.204 -15.241 4.827 1.00 0.00 C +ATOM 1850 CB TYR 198 -0.266 -15.077 4.371 1.00 0.00 C +ATOM 1851 CG TYR 198 -0.521 -14.505 2.977 1.00 0.00 C +ATOM 1852 CD1 TYR 198 -0.758 -13.124 2.795 1.00 0.00 C +ATOM 1853 CE1 TYR 198 -1.063 -12.588 1.521 1.00 0.00 C +ATOM 1854 CD2 TYR 198 -0.596 -15.345 1.840 1.00 0.00 C +ATOM 1855 CE2 TYR 198 -0.903 -14.817 0.558 1.00 0.00 C +ATOM 1856 CZ TYR 198 -1.134 -13.439 0.413 1.00 0.00 C +ATOM 1857 OH TYR 198 -1.432 -12.910 -0.819 1.00 0.00 O +ATOM 1858 HH TYR 198 -1.433 -13.606 -1.480 1.00 0.00 H +ATOM 1859 C TYR 198 1.235 -15.604 6.323 1.00 0.00 C +ATOM 1860 O TYR 198 1.230 -16.794 6.669 1.00 0.00 O +ATOM 1861 N LEU 199 1.291 -14.577 7.185 1.00 0.00 N +ATOM 1862 H LEU 199 1.288 -13.653 6.853 1.00 0.00 H +ATOM 1863 CA LEU 199 1.354 -14.724 8.653 1.00 0.00 C +ATOM 1864 CB LEU 199 2.535 -13.881 9.224 1.00 0.00 C +ATOM 1865 CG LEU 199 3.722 -14.336 10.125 1.00 0.00 C +ATOM 1866 CD1 LEU 199 3.273 -14.771 11.532 1.00 0.00 C +ATOM 1867 CD2 LEU 199 4.611 -15.410 9.470 1.00 0.00 C +ATOM 1868 C LEU 199 0.041 -14.335 9.366 1.00 0.00 C +ATOM 1869 O LEU 199 -0.893 -13.834 8.726 1.00 0.00 O +ATOM 1870 N ALA 200 0.006 -14.553 10.689 1.00 0.00 N +ATOM 1871 H ALA 200 0.790 -14.930 11.144 1.00 0.00 H +ATOM 1872 CA ALA 200 -1.141 -14.271 11.571 1.00 0.00 C +ATOM 1873 CB ALA 200 -1.317 -15.431 12.513 1.00 0.00 C +ATOM 1874 C ALA 200 -0.959 -12.929 12.352 1.00 0.00 C +ATOM 1875 O ALA 200 0.007 -12.219 12.051 1.00 0.00 O +ATOM 1876 N PRO 201 -1.833 -12.560 13.361 1.00 0.00 N +ATOM 1877 CD PRO 201 -1.395 -11.253 13.904 1.00 0.00 C +ATOM 1878 CA PRO 201 -3.047 -12.983 14.113 1.00 0.00 C +ATOM 1879 CB PRO 201 -3.399 -11.726 14.906 1.00 0.00 C +ATOM 1880 CG PRO 201 -2.085 -11.193 15.249 1.00 0.00 C +ATOM 1881 C PRO 201 -4.264 -13.502 13.313 1.00 0.00 C +ATOM 1882 O PRO 201 -4.191 -13.618 12.093 1.00 0.00 O +ATOM 1883 N VAL 202 -5.345 -13.873 14.022 1.00 0.00 N +ATOM 1884 H VAL 202 -5.332 -13.815 15.002 1.00 0.00 H +ATOM 1885 CA VAL 202 -6.600 -14.382 13.424 1.00 0.00 C +ATOM 1886 CB VAL 202 -6.788 -15.954 13.697 1.00 0.00 C +ATOM 1887 CG1 VAL 202 -6.936 -16.274 15.199 1.00 0.00 C +ATOM 1888 CG2 VAL 202 -7.939 -16.543 12.864 1.00 0.00 C +ATOM 1889 C VAL 202 -7.798 -13.536 13.924 1.00 0.00 C +ATOM 1890 O VAL 202 -7.789 -13.074 15.071 1.00 0.00 O +ATOM 1891 N GLY 203 -8.801 -13.342 13.059 1.00 0.00 N +ATOM 1892 H GLY 203 -8.770 -13.715 12.151 1.00 0.00 H +ATOM 1893 CA GLY 203 -9.982 -12.568 13.427 1.00 0.00 C +ATOM 1894 C GLY 203 -10.777 -11.814 12.353 1.00 0.00 C +ATOM 1895 O GLY 203 -11.923 -11.476 12.674 1.00 0.00 O +ATOM 1896 N PRO 204 -10.274 -11.515 11.108 1.00 0.00 N +ATOM 1897 CD PRO 204 -11.248 -10.833 10.228 1.00 0.00 C +ATOM 1898 CA PRO 204 -9.011 -11.725 10.360 1.00 0.00 C +ATOM 1899 CB PRO 204 -9.275 -11.017 9.014 1.00 0.00 C +ATOM 1900 CG PRO 204 -10.366 -10.025 9.318 1.00 0.00 C +ATOM 1901 C PRO 204 -7.694 -11.253 11.024 1.00 0.00 C +ATOM 1902 O PRO 204 -7.705 -10.787 12.169 1.00 0.00 O +ATOM 1903 N TRP 205 -6.588 -11.353 10.274 1.00 0.00 N +ATOM 1904 H TRP 205 -6.688 -11.679 9.355 1.00 0.00 H +ATOM 1905 CA TRP 205 -5.230 -10.980 10.716 1.00 0.00 C +ATOM 1906 CB TRP 205 -4.166 -11.524 9.724 1.00 0.00 C +ATOM 1907 CG TRP 205 -4.651 -12.451 8.569 1.00 0.00 C +ATOM 1908 CD2 TRP 205 -4.596 -13.895 8.511 1.00 0.00 C +ATOM 1909 CE2 TRP 205 -5.116 -14.281 7.243 1.00 0.00 C +ATOM 1910 CE3 TRP 205 -4.159 -14.903 9.401 1.00 0.00 C +ATOM 1911 CD1 TRP 205 -5.187 -12.050 7.368 1.00 0.00 C +ATOM 1912 NE1 TRP 205 -5.464 -13.136 6.578 1.00 0.00 N +ATOM 1913 HE1 TRP 205 -5.829 -13.078 5.680 1.00 0.00 H +ATOM 1914 CZ2 TRP 205 -5.214 -15.635 6.837 1.00 0.00 C +ATOM 1915 CZ3 TRP 205 -4.255 -16.259 8.998 1.00 0.00 C +ATOM 1916 CH2 TRP 205 -4.781 -16.605 7.723 1.00 0.00 C +ATOM 1917 C TRP 205 -5.037 -9.464 10.955 1.00 0.00 C +ATOM 1918 O TRP 205 -5.198 -8.662 10.028 1.00 0.00 O +ATOM 1919 N ASP 206 -4.744 -9.093 12.211 1.00 0.00 N +ATOM 1920 H ASP 206 -4.650 -9.767 12.919 1.00 0.00 H +ATOM 1921 CA ASP 206 -4.543 -7.690 12.630 1.00 0.00 C +ATOM 1922 CB ASP 206 -5.575 -7.288 13.703 1.00 0.00 C +ATOM 1923 CG ASP 206 -7.006 -7.270 13.175 1.00 0.00 C +ATOM 1924 OD1 ASP 206 -7.452 -6.210 12.682 1.00 0.00 O +ATOM 1925 OD2 ASP 206 -7.694 -8.311 13.270 1.00 0.00 O +ATOM 1926 C ASP 206 -3.130 -7.380 13.141 1.00 0.00 C +ATOM 1927 O ASP 206 -2.512 -8.219 13.807 1.00 0.00 O +ATOM 1928 N ASP 207 -2.650 -6.159 12.829 1.00 0.00 N +ATOM 1929 H ASP 207 -3.209 -5.547 12.300 1.00 0.00 H +ATOM 1930 CA ASP 207 -1.325 -5.581 13.195 1.00 0.00 C +ATOM 1931 CB ASP 207 -1.442 -4.738 14.489 1.00 0.00 C +ATOM 1932 CG ASP 207 -0.320 -3.708 14.650 1.00 0.00 C +ATOM 1933 OD1 ASP 207 -0.511 -2.547 14.231 1.00 0.00 O +ATOM 1934 OD2 ASP 207 0.742 -4.058 15.210 1.00 0.00 O +ATOM 1935 C ASP 207 -0.133 -6.564 13.283 1.00 0.00 C +ATOM 1936 O ASP 207 0.009 -7.290 14.280 1.00 0.00 O +ATOM 1937 N TYR 208 0.682 -6.600 12.218 1.00 0.00 N +ATOM 1938 H TYR 208 0.508 -6.024 11.441 1.00 0.00 H +ATOM 1939 CA TYR 208 1.870 -7.469 12.112 1.00 0.00 C +ATOM 1940 CB TYR 208 1.446 -8.956 11.996 1.00 0.00 C +ATOM 1941 CG TYR 208 2.402 -9.989 12.617 1.00 0.00 C +ATOM 1942 CD1 TYR 208 2.193 -10.479 13.930 1.00 0.00 C +ATOM 1943 CE1 TYR 208 3.064 -11.445 14.506 1.00 0.00 C +ATOM 1944 CD2 TYR 208 3.510 -10.495 11.892 1.00 0.00 C +ATOM 1945 CE2 TYR 208 4.386 -11.460 12.461 1.00 0.00 C +ATOM 1946 CZ TYR 208 4.154 -11.927 13.765 1.00 0.00 C +ATOM 1947 OH TYR 208 4.998 -12.862 14.321 1.00 0.00 O +ATOM 1948 HH TYR 208 5.693 -13.095 13.700 1.00 0.00 H +ATOM 1949 C TYR 208 2.711 -7.074 10.885 1.00 0.00 C +ATOM 1950 O TYR 208 2.218 -6.354 10.008 1.00 0.00 O +ATOM 1951 N SER 209 3.969 -7.548 10.835 1.00 0.00 N +ATOM 1952 H SER 209 4.311 -8.114 11.562 1.00 0.00 H +ATOM 1953 CA SER 209 4.922 -7.278 9.735 1.00 0.00 C +ATOM 1954 CB SER 209 5.661 -5.951 9.964 1.00 0.00 C +ATOM 1955 OG SER 209 4.755 -4.872 10.112 1.00 0.00 O +ATOM 1956 HG SER 209 5.249 -4.059 10.238 1.00 0.00 H +ATOM 1957 C SER 209 5.960 -8.398 9.542 1.00 0.00 C +ATOM 1958 O SER 209 6.416 -8.996 10.526 1.00 0.00 O +ATOM 1959 N ILE 210 6.306 -8.680 8.274 1.00 0.00 N +ATOM 1960 H ILE 210 5.888 -8.196 7.530 1.00 0.00 H +ATOM 1961 CA ILE 210 7.300 -9.707 7.888 1.00 0.00 C +ATOM 1962 CB ILE 210 6.638 -10.883 7.009 1.00 0.00 C +ATOM 1963 CG2 ILE 210 6.256 -10.385 5.601 1.00 0.00 C +ATOM 1964 CG1 ILE 210 7.557 -12.121 6.944 1.00 0.00 C +ATOM 1965 CD1 ILE 210 6.907 -13.430 7.398 1.00 0.00 C +ATOM 1966 C ILE 210 8.503 -9.034 7.168 1.00 0.00 C +ATOM 1967 O ILE 210 8.307 -8.191 6.281 1.00 0.00 O +ATOM 1968 N THR 211 9.723 -9.362 7.614 1.00 0.00 N +ATOM 1969 H THR 211 9.824 -9.980 8.372 1.00 0.00 H +ATOM 1970 CA THR 211 10.979 -8.846 7.035 1.00 0.00 C +ATOM 1971 CB THR 211 11.679 -7.826 7.988 1.00 0.00 C +ATOM 1972 OG1 THR 211 10.686 -7.124 8.747 1.00 0.00 O +ATOM 1973 HG1 THR 211 10.205 -7.729 9.317 1.00 0.00 H +ATOM 1974 CG2 THR 211 12.493 -6.793 7.193 1.00 0.00 C +ATOM 1975 C THR 211 11.909 -10.046 6.750 1.00 0.00 C +ATOM 1976 O THR 211 12.067 -10.926 7.609 1.00 0.00 O +ATOM 1977 N ASP 212 12.458 -10.102 5.527 1.00 0.00 N +ATOM 1978 H ASP 212 12.264 -9.405 4.863 1.00 0.00 H +ATOM 1979 CA ASP 212 13.369 -11.179 5.087 1.00 0.00 C +ATOM 1980 CB ASP 212 12.650 -12.147 4.126 1.00 0.00 C +ATOM 1981 CG ASP 212 11.583 -12.981 4.823 1.00 0.00 C +ATOM 1982 OD1 ASP 212 10.475 -12.456 5.074 1.00 0.00 O +ATOM 1983 OD2 ASP 212 11.853 -14.165 5.118 1.00 0.00 O +ATOM 1984 C ASP 212 14.686 -10.695 4.464 1.00 0.00 C +ATOM 1985 O ASP 212 15.762 -11.130 4.890 1.00 0.00 O +ATOM 1986 N GLY 213 14.595 -9.805 3.469 1.00 0.00 N +ATOM 1987 H GLY 213 13.723 -9.472 3.163 1.00 0.00 H +ATOM 1988 CA GLY 213 15.778 -9.287 2.791 1.00 0.00 C +ATOM 1989 C GLY 213 15.832 -7.771 2.702 1.00 0.00 C +ATOM 1990 O GLY 213 15.916 -7.094 3.734 1.00 0.00 O +ATOM 1991 N ARG 214 15.785 -7.250 1.468 1.00 0.00 N +ATOM 1992 H ARG 214 15.717 -7.861 0.703 1.00 0.00 H +ATOM 1993 CA ARG 214 15.828 -5.805 1.165 1.00 0.00 C +ATOM 1994 CB ARG 214 16.491 -5.560 -0.199 1.00 0.00 C +ATOM 1995 CG ARG 214 17.990 -5.864 -0.248 1.00 0.00 C +ATOM 1996 CD ARG 214 18.590 -5.600 -1.628 1.00 0.00 C +ATOM 1997 NE ARG 214 18.136 -6.560 -2.640 1.00 0.00 N +ATOM 1998 HE ARG 214 17.512 -7.260 -2.357 1.00 0.00 H +ATOM 1999 CZ ARG 214 18.505 -6.557 -3.922 1.00 0.00 C +ATOM 2000 NH1 ARG 214 18.024 -7.481 -4.742 1.00 0.00 N +ATOM 2001 HH11 ARG 214 17.389 -8.173 -4.399 1.00 0.00 H +ATOM 2002 HH12 ARG 214 18.296 -7.485 -5.705 1.00 0.00 H +ATOM 2003 NH2 ARG 214 19.349 -5.643 -4.394 1.00 0.00 N +ATOM 2004 HH21 ARG 214 19.718 -4.942 -3.785 1.00 0.00 H +ATOM 2005 HH22 ARG 214 19.613 -5.658 -5.358 1.00 0.00 H +ATOM 2006 C ARG 214 14.423 -5.177 1.175 1.00 0.00 C +ATOM 2007 O ARG 214 14.270 -3.992 1.494 1.00 0.00 O +ATOM 2008 N LEU 215 13.417 -6.000 0.853 1.00 0.00 N +ATOM 2009 H LEU 215 13.597 -6.939 0.628 1.00 0.00 H +ATOM 2010 CA LEU 215 11.997 -5.611 0.801 1.00 0.00 C +ATOM 2011 CB LEU 215 11.325 -6.291 -0.437 1.00 0.00 C +ATOM 2012 CG LEU 215 9.865 -6.493 -0.941 1.00 0.00 C +ATOM 2013 CD1 LEU 215 9.161 -7.553 -0.100 1.00 0.00 C +ATOM 2014 CD2 LEU 215 9.034 -5.207 -1.030 1.00 0.00 C +ATOM 2015 C LEU 215 11.282 -5.975 2.124 1.00 0.00 C +ATOM 2016 O LEU 215 11.448 -7.092 2.632 1.00 0.00 O +ATOM 2017 N VAL 216 10.516 -5.017 2.671 1.00 0.00 N +ATOM 2018 H VAL 216 10.439 -4.137 2.241 1.00 0.00 H +ATOM 2019 CA VAL 216 9.747 -5.192 3.922 1.00 0.00 C +ATOM 2020 CB VAL 216 10.146 -4.134 5.034 1.00 0.00 C +ATOM 2021 CG1 VAL 216 9.663 -4.580 6.426 1.00 0.00 C +ATOM 2022 CG2 VAL 216 11.660 -3.913 5.062 1.00 0.00 C +ATOM 2023 C VAL 216 8.245 -5.063 3.573 1.00 0.00 C +ATOM 2024 O VAL 216 7.831 -4.096 2.919 1.00 0.00 O +ATOM 2025 N THR 217 7.467 -6.083 3.963 1.00 0.00 N +ATOM 2026 H THR 217 7.856 -6.849 4.438 1.00 0.00 H +ATOM 2027 CA THR 217 6.011 -6.163 3.732 1.00 0.00 C +ATOM 2028 CB THR 217 5.675 -7.213 2.648 1.00 0.00 C +ATOM 2029 OG1 THR 217 6.506 -8.364 2.834 1.00 0.00 O +ATOM 2030 HG1 THR 217 6.311 -8.793 3.671 1.00 0.00 H +ATOM 2031 CG2 THR 217 5.900 -6.638 1.259 1.00 0.00 C +ATOM 2032 C THR 217 5.253 -6.504 5.022 1.00 0.00 C +ATOM 2033 O THR 217 5.875 -6.868 6.025 1.00 0.00 O +ATOM 2034 N GLY 218 3.917 -6.380 4.983 1.00 0.00 N +ATOM 2035 H GLY 218 3.462 -6.087 4.163 1.00 0.00 H +ATOM 2036 CA GLY 218 3.062 -6.666 6.132 1.00 0.00 C +ATOM 2037 C GLY 218 2.928 -5.444 7.013 1.00 0.00 C +ATOM 2038 O GLY 218 3.927 -5.016 7.595 1.00 0.00 O +ATOM 2039 N VAL 219 1.733 -4.839 7.053 1.00 0.00 N +ATOM 2040 H VAL 219 0.989 -5.223 6.544 1.00 0.00 H +ATOM 2041 CA VAL 219 1.488 -3.611 7.835 1.00 0.00 C +ATOM 2042 CB VAL 219 1.723 -2.325 6.930 1.00 0.00 C +ATOM 2043 CG1 VAL 219 1.339 -1.028 7.619 1.00 0.00 C +ATOM 2044 CG2 VAL 219 3.179 -2.225 6.514 1.00 0.00 C +ATOM 2045 C VAL 219 0.139 -3.542 8.590 1.00 0.00 C +ATOM 2046 O VAL 219 0.026 -4.121 9.674 1.00 0.00 O +ATOM 2047 N ASN 220 -0.858 -2.861 7.984 1.00 0.00 N +ATOM 2048 H ASN 220 -0.747 -2.518 7.073 1.00 0.00 H +ATOM 2049 CA ASN 220 -2.236 -2.542 8.462 1.00 0.00 C +ATOM 2050 CB ASN 220 -2.758 -3.444 9.605 1.00 0.00 C +ATOM 2051 CG ASN 220 -2.794 -4.923 9.235 1.00 0.00 C +ATOM 2052 OD1 ASN 220 -2.490 -5.776 10.067 1.00 0.00 O +ATOM 2053 ND2 ASN 220 -3.174 -5.233 7.994 1.00 0.00 N +ATOM 2054 HD21 ASN 220 -3.434 -4.531 7.365 1.00 0.00 H +ATOM 2055 HD22 ASN 220 -3.182 -6.170 7.734 1.00 0.00 H +ATOM 2056 C ASN 220 -2.213 -1.062 8.917 1.00 0.00 C +ATOM 2057 O ASN 220 -1.150 -0.591 9.337 1.00 0.00 O +ATOM 2058 N PRO 221 -3.361 -0.310 8.860 1.00 0.00 N +ATOM 2059 CD PRO 221 -4.677 -0.650 8.268 1.00 0.00 C +ATOM 2060 CA PRO 221 -3.378 1.110 9.283 1.00 0.00 C +ATOM 2061 CB PRO 221 -4.826 1.530 8.998 1.00 0.00 C +ATOM 2062 CG PRO 221 -5.197 0.693 7.838 1.00 0.00 C +ATOM 2063 C PRO 221 -2.938 1.462 10.733 1.00 0.00 C +ATOM 2064 O PRO 221 -3.100 2.610 11.175 1.00 0.00 O +ATOM 2065 N ALA 222 -2.341 0.483 11.427 1.00 0.00 N +ATOM 2066 H ALA 222 -2.216 -0.411 11.063 1.00 0.00 H +ATOM 2067 CA ALA 222 -1.846 0.622 12.806 1.00 0.00 C +ATOM 2068 CB ALA 222 -2.661 -0.275 13.749 1.00 0.00 C +ATOM 2069 C ALA 222 -0.352 0.272 12.916 1.00 0.00 C +ATOM 2070 O ALA 222 0.321 0.729 13.849 1.00 0.00 O +ATOM 2071 N SER 223 0.154 -0.519 11.957 1.00 0.00 N +ATOM 2072 H SER 223 -0.414 -0.824 11.216 1.00 0.00 H +ATOM 2073 CA SER 223 1.556 -0.986 11.927 1.00 0.00 C +ATOM 2074 CB SER 223 1.581 -2.514 11.768 1.00 0.00 C +ATOM 2075 OG SER 223 2.875 -3.050 12.000 1.00 0.00 O +ATOM 2076 HG SER 223 2.851 -4.003 11.892 1.00 0.00 H +ATOM 2077 C SER 223 2.479 -0.318 10.880 1.00 0.00 C +ATOM 2078 O SER 223 3.525 -0.877 10.528 1.00 0.00 O +ATOM 2079 N ALA 224 2.106 0.875 10.404 1.00 0.00 N +ATOM 2080 H ALA 224 1.270 1.288 10.711 1.00 0.00 H +ATOM 2081 CA ALA 224 2.890 1.646 9.415 1.00 0.00 C +ATOM 2082 CB ALA 224 2.073 2.780 8.850 1.00 0.00 C +ATOM 2083 C ALA 224 4.217 2.138 10.012 1.00 0.00 C +ATOM 2084 O ALA 224 5.211 2.292 9.292 1.00 0.00 O +ATOM 2085 N HIS 225 4.192 2.420 11.323 1.00 0.00 N +ATOM 2086 H HIS 225 3.345 2.334 11.816 1.00 0.00 H +ATOM 2087 CA HIS 225 5.356 2.863 12.116 1.00 0.00 C +ATOM 2088 CB HIS 225 4.949 3.137 13.576 1.00 0.00 C +ATOM 2089 CG HIS 225 4.026 4.309 13.751 1.00 0.00 C +ATOM 2090 CD2 HIS 225 2.728 4.372 14.137 1.00 0.00 C +ATOM 2091 ND1 HIS 225 4.426 5.613 13.547 1.00 0.00 N +ATOM 2092 HD1 HIS 225 5.318 5.898 13.260 1.00 0.00 H +ATOM 2093 CE1 HIS 225 3.417 6.428 13.800 1.00 0.00 C +ATOM 2094 NE2 HIS 225 2.376 5.700 14.160 1.00 0.00 N +ATOM 2095 HE2 HIS 225 1.494 6.051 14.404 1.00 0.00 H +ATOM 2096 C HIS 225 6.475 1.803 12.080 1.00 0.00 C +ATOM 2097 O HIS 225 7.660 2.156 12.053 1.00 0.00 O +ATOM 2098 N SER 226 6.078 0.517 12.052 1.00 0.00 N +ATOM 2099 H SER 226 5.118 0.307 12.058 1.00 0.00 H +ATOM 2100 CA SER 226 6.998 -0.642 12.010 1.00 0.00 C +ATOM 2101 CB SER 226 6.240 -1.960 12.282 1.00 0.00 C +ATOM 2102 OG SER 226 5.358 -2.304 11.228 1.00 0.00 O +ATOM 2103 HG SER 226 4.911 -3.127 11.440 1.00 0.00 H +ATOM 2104 C SER 226 7.790 -0.734 10.687 1.00 0.00 C +ATOM 2105 O SER 226 9.013 -0.918 10.715 1.00 0.00 O +ATOM 2106 N THR 227 7.093 -0.571 9.550 1.00 0.00 N +ATOM 2107 H THR 227 6.124 -0.411 9.600 1.00 0.00 H +ATOM 2108 CA THR 227 7.705 -0.612 8.202 1.00 0.00 C +ATOM 2109 CB THR 227 6.632 -0.811 7.058 1.00 0.00 C +ATOM 2110 OG1 THR 227 7.290 -0.939 5.790 1.00 0.00 O +ATOM 2111 HG1 THR 227 7.850 -1.720 5.781 1.00 0.00 H +ATOM 2112 CG2 THR 227 5.617 0.346 6.993 1.00 0.00 C +ATOM 2113 C THR 227 8.615 0.609 7.931 1.00 0.00 C +ATOM 2114 O THR 227 9.683 0.468 7.323 1.00 0.00 O +ATOM 2115 N ALA 228 8.183 1.782 8.420 1.00 0.00 N +ATOM 2116 H ALA 228 7.327 1.828 8.905 1.00 0.00 H +ATOM 2117 CA ALA 228 8.906 3.059 8.277 1.00 0.00 C +ATOM 2118 CB ALA 228 8.011 4.220 8.685 1.00 0.00 C +ATOM 2119 C ALA 228 10.218 3.081 9.081 1.00 0.00 C +ATOM 2120 O ALA 228 11.249 3.526 8.561 1.00 0.00 O +ATOM 2121 N VAL 229 10.173 2.563 10.320 1.00 0.00 N +ATOM 2122 H VAL 229 9.319 2.210 10.662 1.00 0.00 H +ATOM 2123 CA VAL 229 11.343 2.486 11.223 1.00 0.00 C +ATOM 2124 CB VAL 229 10.912 2.224 12.734 1.00 0.00 C +ATOM 2125 CG1 VAL 229 10.391 0.797 12.958 1.00 0.00 C +ATOM 2126 CG2 VAL 229 12.043 2.581 13.712 1.00 0.00 C +ATOM 2127 C VAL 229 12.383 1.468 10.680 1.00 0.00 C +ATOM 2128 O VAL 229 13.591 1.728 10.731 1.00 0.00 O +ATOM 2129 N ARG 230 11.883 0.343 10.146 1.00 0.00 N +ATOM 2130 H ARG 230 10.907 0.195 10.147 1.00 0.00 H +ATOM 2131 CA ARG 230 12.700 -0.735 9.552 1.00 0.00 C +ATOM 2132 CB ARG 230 11.859 -1.996 9.315 1.00 0.00 C +ATOM 2133 CG ARG 230 11.579 -2.805 10.576 1.00 0.00 C +ATOM 2134 CD ARG 230 10.700 -4.011 10.283 1.00 0.00 C +ATOM 2135 NE ARG 230 10.424 -4.794 11.489 1.00 0.00 N +ATOM 2136 HE ARG 230 10.907 -4.562 12.310 1.00 0.00 H +ATOM 2137 CZ ARG 230 9.562 -5.809 11.567 1.00 0.00 C +ATOM 2138 NH1 ARG 230 9.401 -6.442 12.721 1.00 0.00 N +ATOM 2139 HH11 ARG 230 9.923 -6.157 13.525 1.00 0.00 H +ATOM 2140 HH12 ARG 230 8.756 -7.204 12.787 1.00 0.00 H +ATOM 2141 NH2 ARG 230 8.858 -6.197 10.508 1.00 0.00 N +ATOM 2142 HH21 ARG 230 8.970 -5.726 9.633 1.00 0.00 H +ATOM 2143 HH22 ARG 230 8.217 -6.961 10.587 1.00 0.00 H +ATOM 2144 C ARG 230 13.376 -0.294 8.242 1.00 0.00 C +ATOM 2145 O ARG 230 14.525 -0.672 7.983 1.00 0.00 O +ATOM 2146 N SER 231 12.661 0.518 7.445 1.00 0.00 N +ATOM 2147 H SER 231 11.751 0.782 7.713 1.00 0.00 H +ATOM 2148 CA SER 231 13.145 1.062 6.157 1.00 0.00 C +ATOM 2149 CB SER 231 11.992 1.696 5.362 1.00 0.00 C +ATOM 2150 OG SER 231 11.062 0.716 4.933 1.00 0.00 O +ATOM 2151 HG SER 231 10.683 0.235 5.671 1.00 0.00 H +ATOM 2152 C SER 231 14.290 2.076 6.342 1.00 0.00 C +ATOM 2153 O SER 231 15.304 1.990 5.638 1.00 0.00 O +ATOM 2154 N ILE 232 14.129 3.009 7.296 1.00 0.00 N +ATOM 2155 H ILE 232 13.294 3.031 7.821 1.00 0.00 H +ATOM 2156 CA ILE 232 15.149 4.036 7.610 1.00 0.00 C +ATOM 2157 CB ILE 232 14.573 5.270 8.421 1.00 0.00 C +ATOM 2158 CG2 ILE 232 13.626 6.078 7.516 1.00 0.00 C +ATOM 2159 CG1 ILE 232 13.890 4.837 9.736 1.00 0.00 C +ATOM 2160 CD1 ILE 232 13.998 5.838 10.895 1.00 0.00 C +ATOM 2161 C ILE 232 16.415 3.450 8.280 1.00 0.00 C +ATOM 2162 O ILE 232 17.534 3.871 7.966 1.00 0.00 O +ATOM 2163 N ASP 233 16.214 2.455 9.159 1.00 0.00 N +ATOM 2164 H ASP 233 15.292 2.159 9.351 1.00 0.00 H +ATOM 2165 CA ASP 233 17.289 1.753 9.893 1.00 0.00 C +ATOM 2166 CB ASP 233 16.687 0.861 10.998 1.00 0.00 C +ATOM 2167 CG ASP 233 17.637 0.640 12.178 1.00 0.00 C +ATOM 2168 OD1 ASP 233 17.595 1.439 13.140 1.00 0.00 O +ATOM 2169 OD2 ASP 233 18.412 -0.341 12.148 1.00 0.00 O +ATOM 2170 C ASP 233 18.137 0.911 8.913 1.00 0.00 C +ATOM 2171 O ASP 233 19.366 0.867 9.037 1.00 0.00 O +ATOM 2172 N ALA 234 17.459 0.255 7.958 1.00 0.00 N +ATOM 2173 H ALA 234 16.475 0.307 7.932 1.00 0.00 H +ATOM 2174 CA ALA 234 18.076 -0.580 6.907 1.00 0.00 C +ATOM 2175 CB ALA 234 17.012 -1.400 6.190 1.00 0.00 C +ATOM 2176 C ALA 234 18.856 0.277 5.895 1.00 0.00 C +ATOM 2177 O ALA 234 19.912 -0.142 5.407 1.00 0.00 O +ATOM 2178 N LEU 235 18.311 1.467 5.596 1.00 0.00 N +ATOM 2179 H LEU 235 17.456 1.724 6.013 1.00 0.00 H +ATOM 2180 CA LEU 235 18.890 2.452 4.658 1.00 0.00 C +ATOM 2181 CB LEU 235 17.844 3.559 4.330 1.00 0.00 C +ATOM 2182 CG LEU 235 17.649 4.398 3.030 1.00 0.00 C +ATOM 2183 CD1 LEU 235 18.799 5.389 2.782 1.00 0.00 C +ATOM 2184 CD2 LEU 235 17.384 3.529 1.786 1.00 0.00 C +ATOM 2185 C LEU 235 20.193 3.081 5.197 1.00 0.00 C +ATOM 2186 O LEU 235 21.125 3.332 4.424 1.00 0.00 O +ATOM 2187 N LYS 236 20.232 3.324 6.516 1.00 0.00 N +ATOM 2188 H LYS 236 19.443 3.116 7.070 1.00 0.00 H +ATOM 2189 CA LYS 236 21.389 3.913 7.226 1.00 0.00 C +ATOM 2190 CB LYS 236 20.995 4.343 8.645 1.00 0.00 C +ATOM 2191 CG LYS 236 20.133 5.596 8.707 1.00 0.00 C +ATOM 2192 CD LYS 236 19.759 5.938 10.143 1.00 0.00 C +ATOM 2193 CE LYS 236 18.869 7.173 10.224 1.00 0.00 C +ATOM 2194 NZ LYS 236 17.498 6.955 9.672 1.00 0.00 N +ATOM 2195 HZ1 LYS 236 17.028 6.196 10.204 1.00 0.00 H +ATOM 2196 HZ2 LYS 236 17.568 6.684 8.670 1.00 0.00 H +ATOM 2197 HZ3 LYS 236 16.944 7.830 9.755 1.00 0.00 H +ATOM 2198 C LYS 236 22.620 2.993 7.286 1.00 0.00 C +ATOM 2199 O LYS 236 23.753 3.472 7.172 1.00 0.00 O +ATOM 2200 N ASN 237 22.381 1.679 7.453 1.00 0.00 N +ATOM 2201 H ASN 237 21.453 1.366 7.534 1.00 0.00 H +ATOM 2202 CA ASN 237 23.401 0.595 7.533 1.00 0.00 C +ATOM 2203 CB ASN 237 24.030 0.311 6.145 1.00 0.00 C +ATOM 2204 CG ASN 237 23.025 -0.241 5.141 1.00 0.00 C +ATOM 2205 OD1 ASN 237 22.850 -1.456 5.023 1.00 0.00 O +ATOM 2206 ND2 ASN 237 22.373 0.651 4.401 1.00 0.00 N +ATOM 2207 HD21 ASN 237 21.723 0.312 3.750 1.00 0.00 H +ATOM 2208 HD22 ASN 237 22.559 1.606 4.526 1.00 0.00 H +ATOM 2209 C ASN 237 24.505 0.747 8.612 1.00 0.00 C +ATOM 2210 O ASN 237 25.454 -0.052 8.656 1.00 0.00 O +ATOM 2211 N HIS 238 24.334 1.734 9.504 1.00 0.00 N +ATOM 2212 H HIS 238 23.541 2.311 9.460 1.00 0.00 H +ATOM 2213 CA HIS 238 25.283 2.030 10.595 1.00 0.00 C +ATOM 2214 CB HIS 238 25.390 3.560 10.800 1.00 0.00 C +ATOM 2215 CG HIS 238 26.705 4.023 11.364 1.00 0.00 C +ATOM 2216 CD2 HIS 238 27.696 4.771 10.820 1.00 0.00 C +ATOM 2217 ND1 HIS 238 27.109 3.735 12.651 1.00 0.00 N +ATOM 2218 HD1 HIS 238 26.604 3.206 13.304 1.00 0.00 H +ATOM 2219 CE1 HIS 238 28.290 4.283 12.875 1.00 0.00 C +ATOM 2220 NE2 HIS 238 28.668 4.917 11.780 1.00 0.00 N +ATOM 2221 HE2 HIS 238 29.506 5.412 11.670 1.00 0.00 H +ATOM 2222 C HIS 238 24.886 1.317 11.910 1.00 0.00 C +ATOM 2223 O HIS 238 25.703 0.585 12.481 1.00 0.00 O +ATOM 2224 N HIS 239 23.645 1.541 12.368 1.00 0.00 N +ATOM 2225 H HIS 239 23.037 2.135 11.877 1.00 0.00 H +ATOM 2226 CA HIS 239 23.101 0.939 13.601 1.00 0.00 C +ATOM 2227 CB HIS 239 22.778 2.019 14.670 1.00 0.00 C +ATOM 2228 CG HIS 239 22.075 3.240 14.143 1.00 0.00 C +ATOM 2229 CD2 HIS 239 20.813 3.696 14.332 1.00 0.00 C +ATOM 2230 ND1 HIS 239 22.697 4.168 13.333 1.00 0.00 N +ATOM 2231 HD1 HIS 239 23.623 4.119 13.015 1.00 0.00 H +ATOM 2232 CE1 HIS 239 21.850 5.140 13.046 1.00 0.00 C +ATOM 2233 NE2 HIS 239 20.700 4.878 13.640 1.00 0.00 N +ATOM 2234 HE2 HIS 239 19.896 5.436 13.594 1.00 0.00 H +ATOM 2235 C HIS 239 21.875 0.047 13.335 1.00 0.00 C +ATOM 2236 O HIS 239 21.055 0.364 12.464 1.00 0.00 O +ATOM 2237 N HIS 240 21.772 -1.057 14.089 1.00 0.00 N +ATOM 2238 H HIS 240 22.454 -1.261 14.766 1.00 0.00 H +ATOM 2239 CA HIS 240 20.671 -2.034 13.983 1.00 0.00 C +ATOM 2240 CB HIS 240 21.221 -3.480 13.852 1.00 0.00 C +ATOM 2241 CG HIS 240 22.301 -3.837 14.837 1.00 0.00 C +ATOM 2242 CD2 HIS 240 23.619 -4.099 14.660 1.00 0.00 C +ATOM 2243 ND1 HIS 240 22.064 -3.980 16.188 1.00 0.00 N +ATOM 2244 HD1 HIS 240 21.199 -3.855 16.633 1.00 0.00 H +ATOM 2245 CE1 HIS 240 23.186 -4.313 16.801 1.00 0.00 C +ATOM 2246 NE2 HIS 240 24.145 -4.392 15.896 1.00 0.00 N +ATOM 2247 HE2 HIS 240 25.080 -4.623 16.076 1.00 0.00 H +ATOM 2248 C HIS 240 19.647 -1.929 15.131 1.00 0.00 C +ATOM 2249 O HIS 240 20.003 -1.506 16.235 1.00 0.00 O +ATOM 2250 N HIS 241 18.396 -2.337 14.846 1.00 0.00 N +ATOM 2251 H HIS 241 18.201 -2.677 13.945 1.00 0.00 H +ATOM 2252 CA HIS 241 17.212 -2.345 15.752 1.00 0.00 C +ATOM 2253 CB HIS 241 16.965 -3.748 16.382 1.00 0.00 C +ATOM 2254 CG HIS 241 18.160 -4.360 17.061 1.00 0.00 C +ATOM 2255 CD2 HIS 241 18.948 -5.406 16.708 1.00 0.00 C +ATOM 2256 ND1 HIS 241 18.641 -3.914 18.273 1.00 0.00 N +ATOM 2257 HD1 HIS 241 18.280 -3.163 18.790 1.00 0.00 H +ATOM 2258 CE1 HIS 241 19.671 -4.656 18.639 1.00 0.00 C +ATOM 2259 NE2 HIS 241 19.878 -5.568 17.706 1.00 0.00 N +ATOM 2260 HE2 HIS 241 20.581 -6.250 17.724 1.00 0.00 H +ATOM 2261 C HIS 241 16.974 -1.218 16.788 1.00 0.00 C +ATOM 2262 O HIS 241 15.908 -0.590 16.768 1.00 0.00 O +ATOM 2263 N HIS 242 17.954 -0.976 17.670 1.00 0.00 N +ATOM 2264 H HIS 242 18.769 -1.519 17.669 1.00 0.00 H +ATOM 2265 CA HIS 242 17.880 0.063 18.719 1.00 0.00 C +ATOM 2266 CB HIS 242 18.676 -0.370 19.977 1.00 0.00 C +ATOM 2267 CG HIS 242 20.128 -0.683 19.730 1.00 0.00 C +ATOM 2268 CD2 HIS 242 21.256 -0.131 20.239 1.00 0.00 C +ATOM 2269 ND1 HIS 242 20.546 -1.683 18.878 1.00 0.00 N +ATOM 2270 HD1 HIS 242 19.958 -2.258 18.346 1.00 0.00 H +ATOM 2271 CE1 HIS 242 21.866 -1.735 18.872 1.00 0.00 C +ATOM 2272 NE2 HIS 242 22.321 -0.803 19.690 1.00 0.00 N +ATOM 2273 HE2 HIS 242 23.266 -0.621 19.875 1.00 0.00 H +ATOM 2274 C HIS 242 18.300 1.477 18.258 1.00 0.00 C +ATOM 2275 O HIS 242 19.190 1.612 17.409 1.00 0.00 O +ATOM 2276 N HIS 243 17.651 2.503 18.827 1.00 0.00 N +ATOM 2277 H HIS 243 16.952 2.336 19.497 1.00 0.00 H +ATOM 2278 CA HIS 243 17.909 3.922 18.519 1.00 0.00 C +ATOM 2279 CB HIS 243 16.585 4.637 18.159 1.00 0.00 C +ATOM 2280 CG HIS 243 16.746 5.831 17.259 1.00 0.00 C +ATOM 2281 CD2 HIS 243 16.539 7.152 17.482 1.00 0.00 C +ATOM 2282 ND1 HIS 243 17.149 5.727 15.944 1.00 0.00 N +ATOM 2283 HD1 HIS 243 17.376 4.894 15.480 1.00 0.00 H +ATOM 2284 CE1 HIS 243 17.184 6.929 15.397 1.00 0.00 C +ATOM 2285 NE2 HIS 243 16.818 7.811 16.309 1.00 0.00 N +ATOM 2286 HE2 HIS 243 16.756 8.779 16.172 1.00 0.00 H +ATOM 2287 C HIS 243 18.578 4.601 19.722 1.00 0.00 C +ATOM 2288 O HIS 243 18.290 4.189 20.866 1.00 0.00 O +ATOM 2289 OXT HIS 243 19.385 5.529 19.501 1.00 0.00 O +END diff --git a/examples/testdata/raptorxeg/models/195600_model_4.pdb b/examples/testdata/raptorxeg/models/195600_model_4.pdb new file mode 100644 index 0000000..eb684bc --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600_model_4.pdb @@ -0,0 +1,2358 @@ +REMARK FILENAME="17_195600_4.pdb" +REMARK The macromolecule has 243 residues +REMARK Trial structure 4 of 10 structures +REMARK Molecular dynamics scheme : cartesian; cartesian; minimize +REMARK High temperature dynamics : +REMARK temp: 2000 steps: 1000 time(ps): 3 +REMARK 1st cooling stage : +REMARK temp: 2000->0 steps: 1000 time(ps): 5 temp step: 25 +REMARK 2nd cooling stage not used: +REMARK a total 36450 steps of minimization +REMARK VDW scale factors 20 20 0.01 0.003 0.003; 3E-03->4; 1 +REMARK 1070 NOEs in 3 class(es) with scale factors of 10; 10; 10 +REMARK averaging function(s): cent, sum, hbnd: cent +REMARK 0 3-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 1-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 carbon chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 proton chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 diffusion anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 susceptability anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 188 dihedral restraints with scale factors of 5; 50; 50 +REMARK 0 planarity restraints with a scale factor of NA +REMARK NCS restraints not used. +REMARK =============================================================== +REMARK bond, angles, improp, vdw(<1.6), dihed +REMARK violations : 25 205 23 3 287 +REMARK RMSD : 0.0172 2.451 1.766 23.177 +REMARK =============================================================== +REMARK noe, cdih, coup, oneb, carb-a, carb-b, +REMARK violations : 126 9 0 0 0 ----- +REMARK RMSD : 0.713 2.449 0.000 0.000 0.000 0.000 +REMARK 0.2/2 viol.: 259 44 0 +REMARK =============================================================== +REMARK dani, sani +REMARK violations : 0 0 +REMARK RMSD : 0.000 0.000 +REMARK .2/.1 viol.: 0 0 +REMARK =============================================================== +REMARK Protons violations, rmsd +REMARK all : 0 0.000 +REMARK class 1: 0 0.000 +REMARK class 2: 0 0.000 +REMARK class 3: 0 0.000 +REMARK class 4: 0 0.000 +REMARK =============================================================== +REMARK overall = 13627.9 +REMARK bon = 859.895 +REMARK ang = 1505.32 +REMARK imp = 312.812 +REMARK vdw = 8093.12 +REMARK harm = 0 +REMARK noe = 1944.29 +REMARK coup = 0 +REMARK oneb = 0 +REMARK carb = 0 +REMARK prot = 0 +REMARK dani = 0 +REMARK sani = 0 +REMARK cdih = 85.8989 +REMARK ncs = 0 +REMARK =============================================================== +REMARK DATE:15-Jan-2017 12:30:25 created by user: RaptorX +REMARK VERSION:1.3 +ATOM 1 CB MET 1 18.356 15.599 8.421 1.00 0.00 C +ATOM 2 CG MET 1 18.099 17.128 8.510 1.00 0.00 C +ATOM 3 SD MET 1 19.072 17.994 9.769 1.00 0.00 S +ATOM 4 CE MET 1 20.175 18.965 8.742 1.00 0.00 C +ATOM 5 C MET 1 19.736 15.188 6.315 1.00 0.00 C +ATOM 6 O MET 1 20.108 16.222 5.747 1.00 0.00 O +ATOM 7 HT1 MET 1 21.749 15.424 8.181 1.00 0.00 H +ATOM 8 HT2 MET 1 20.830 16.846 8.184 1.00 0.00 H +ATOM 9 N MET 1 20.852 15.853 8.486 1.00 0.00 N +ATOM 10 HT3 MET 1 20.774 15.797 9.521 1.00 0.00 H +ATOM 11 CA MET 1 19.715 15.120 7.854 1.00 0.00 C +ATOM 12 N ALA 2 19.336 14.085 5.668 1.00 0.00 N +ATOM 13 H ALA 2 19.050 13.290 6.170 1.00 0.00 H +ATOM 14 CA ALA 2 19.287 13.960 4.201 1.00 0.00 C +ATOM 15 CB ALA 2 20.055 12.726 3.751 1.00 0.00 C +ATOM 16 C ALA 2 17.834 13.889 3.686 1.00 0.00 C +ATOM 17 O ALA 2 16.973 13.352 4.392 1.00 0.00 O +ATOM 18 N PRO 3 17.538 14.424 2.457 1.00 0.00 N +ATOM 19 CD PRO 3 18.395 15.279 1.603 1.00 0.00 C +ATOM 20 CA PRO 3 16.171 14.394 1.891 1.00 0.00 C +ATOM 21 CB PRO 3 16.304 15.250 0.628 1.00 0.00 C +ATOM 22 CG PRO 3 17.391 16.203 0.969 1.00 0.00 C +ATOM 23 C PRO 3 15.626 12.991 1.544 1.00 0.00 C +ATOM 24 O PRO 3 14.486 12.668 1.896 1.00 0.00 O +ATOM 25 N LYS 4 16.458 12.172 0.872 1.00 0.00 N +ATOM 26 H LYS 4 17.360 12.488 0.645 1.00 0.00 H +ATOM 27 CA LYS 4 16.163 10.786 0.414 1.00 0.00 C +ATOM 28 CB LYS 4 15.949 9.810 1.593 1.00 0.00 C +ATOM 29 CG LYS 4 17.223 9.426 2.334 1.00 0.00 C +ATOM 30 CD LYS 4 17.017 8.171 3.178 1.00 0.00 C +ATOM 31 CE LYS 4 18.295 7.738 3.893 1.00 0.00 C +ATOM 32 NZ LYS 4 19.354 7.229 2.969 1.00 0.00 N +ATOM 33 HZ1 LYS 4 19.613 7.977 2.294 1.00 0.00 H +ATOM 34 HZ2 LYS 4 18.993 6.403 2.450 1.00 0.00 H +ATOM 35 HZ3 LYS 4 20.191 6.954 3.521 1.00 0.00 H +ATOM 36 C LYS 4 15.033 10.618 -0.623 1.00 0.00 C +ATOM 37 O LYS 4 15.133 9.763 -1.510 1.00 0.00 O +ATOM 38 N LYS 5 13.991 11.461 -0.520 1.00 0.00 N +ATOM 39 H LYS 5 13.962 12.147 0.167 1.00 0.00 H +ATOM 40 CA LYS 5 12.778 11.493 -1.384 1.00 0.00 C +ATOM 41 CB LYS 5 13.088 12.010 -2.807 1.00 0.00 C +ATOM 42 CG LYS 5 13.490 13.478 -2.877 1.00 0.00 C +ATOM 43 CD LYS 5 13.778 13.906 -4.312 1.00 0.00 C +ATOM 44 CE LYS 5 14.183 15.375 -4.406 1.00 0.00 C +ATOM 45 NZ LYS 5 13.071 16.323 -4.096 1.00 0.00 N +ATOM 46 HZ1 LYS 5 12.290 16.173 -4.766 1.00 0.00 H +ATOM 47 HZ2 LYS 5 13.416 17.301 -4.178 1.00 0.00 H +ATOM 48 HZ3 LYS 5 12.733 16.155 -3.126 1.00 0.00 H +ATOM 49 C LYS 5 11.987 10.170 -1.447 1.00 0.00 C +ATOM 50 O LYS 5 12.556 9.112 -1.751 1.00 0.00 O +ATOM 51 N VAL 6 10.683 10.251 -1.139 1.00 0.00 N +ATOM 52 H VAL 6 10.282 11.115 -0.900 1.00 0.00 H +ATOM 53 CA VAL 6 9.757 9.097 -1.130 1.00 0.00 C +ATOM 54 CB VAL 6 9.239 8.730 0.331 1.00 0.00 C +ATOM 55 CG1 VAL 6 8.706 7.286 0.383 1.00 0.00 C +ATOM 56 CG2 VAL 6 10.343 8.906 1.372 1.00 0.00 C +ATOM 57 C VAL 6 8.554 9.419 -2.037 1.00 0.00 C +ATOM 58 O VAL 6 8.124 10.577 -2.112 1.00 0.00 O +ATOM 59 N LEU 7 8.061 8.397 -2.750 1.00 0.00 N +ATOM 60 H LEU 7 8.470 7.506 -2.693 1.00 0.00 H +ATOM 61 CA LEU 7 6.903 8.511 -3.656 1.00 0.00 C +ATOM 62 CB LEU 7 7.292 8.132 -5.107 1.00 0.00 C +ATOM 63 CG LEU 7 8.349 8.921 -5.905 1.00 0.00 C +ATOM 64 CD1 LEU 7 9.193 7.943 -6.707 1.00 0.00 C +ATOM 65 CD2 LEU 7 7.723 9.975 -6.830 1.00 0.00 C +ATOM 66 C LEU 7 5.764 7.608 -3.139 1.00 0.00 C +ATOM 67 O LEU 7 5.986 6.419 -2.867 1.00 0.00 O +ATOM 68 N LEU 8 4.571 8.197 -2.973 1.00 0.00 N +ATOM 69 H LEU 8 4.458 9.150 -3.181 1.00 0.00 H +ATOM 70 CA LEU 8 3.359 7.510 -2.482 1.00 0.00 C +ATOM 71 CB LEU 8 2.754 8.266 -1.269 1.00 0.00 C +ATOM 72 CG LEU 8 3.333 8.498 0.157 1.00 0.00 C +ATOM 73 CD1 LEU 8 3.391 7.206 0.989 1.00 0.00 C +ATOM 74 CD2 LEU 8 4.689 9.228 0.166 1.00 0.00 C +ATOM 75 C LEU 8 2.309 7.367 -3.592 1.00 0.00 C +ATOM 76 O LEU 8 2.173 8.268 -4.420 1.00 0.00 O +ATOM 77 N ALA 9 1.579 6.242 -3.594 1.00 0.00 N +ATOM 78 H ALA 9 1.714 5.562 -2.897 1.00 0.00 H +ATOM 79 CA ALA 9 0.547 5.931 -4.602 1.00 0.00 C +ATOM 80 CB ALA 9 0.817 4.550 -5.210 1.00 0.00 C +ATOM 81 C ALA 9 -0.897 5.995 -4.071 1.00 0.00 C +ATOM 82 O ALA 9 -1.176 5.499 -2.973 1.00 0.00 O +ATOM 83 N LEU 10 -1.790 6.624 -4.853 1.00 0.00 N +ATOM 84 H LEU 10 -1.506 7.026 -5.703 1.00 0.00 H +ATOM 85 CA LEU 10 -3.227 6.771 -4.532 1.00 0.00 C +ATOM 86 CB LEU 10 -3.592 8.249 -4.217 1.00 0.00 C +ATOM 87 CG LEU 10 -4.566 8.848 -3.159 1.00 0.00 C +ATOM 88 CD1 LEU 10 -5.920 8.122 -3.036 1.00 0.00 C +ATOM 89 CD2 LEU 10 -3.877 8.964 -1.798 1.00 0.00 C +ATOM 90 C LEU 10 -4.068 6.268 -5.721 1.00 0.00 C +ATOM 91 O LEU 10 -3.538 6.115 -6.828 1.00 0.00 O +ATOM 92 N THR 11 -5.367 6.021 -5.479 1.00 0.00 N +ATOM 93 H THR 11 -5.740 6.166 -4.583 1.00 0.00 H +ATOM 94 CA THR 11 -6.317 5.519 -6.492 1.00 0.00 C +ATOM 95 OG1 THR 11 -5.588 3.344 -5.677 1.00 0.00 O +ATOM 96 HG1 THR 11 -4.907 3.281 -6.353 1.00 0.00 H +ATOM 97 CG2 THR 11 -7.176 3.303 -7.440 1.00 0.00 C +ATOM 98 C THR 11 -7.562 6.430 -6.642 1.00 0.00 C +ATOM 99 O THR 11 -8.443 6.148 -7.468 1.00 0.00 O +ATOM 100 CB THR 11 -6.734 4.040 -6.166 1.00 0.00 C +ATOM 101 N SER 12 -7.588 7.547 -5.894 1.00 0.00 N +ATOM 102 H SER 12 -6.829 7.745 -5.307 1.00 0.00 H +ATOM 103 CA SER 12 -8.679 8.565 -5.867 1.00 0.00 C +ATOM 104 CB SER 12 -8.831 9.289 -7.223 1.00 0.00 C +ATOM 105 OG SER 12 -9.256 8.421 -8.261 1.00 0.00 O +ATOM 106 HG SER 12 -9.335 8.917 -9.080 1.00 0.00 H +ATOM 107 C SER 12 -10.049 8.059 -5.365 1.00 0.00 C +ATOM 108 O SER 12 -11.104 8.610 -5.722 1.00 0.00 O +ATOM 109 N TYR 13 -10.008 7.033 -4.511 1.00 0.00 N +ATOM 110 H TYR 13 -9.149 6.646 -4.231 1.00 0.00 H +ATOM 111 CA TYR 13 -11.203 6.407 -3.928 1.00 0.00 C +ATOM 112 CB TYR 13 -11.264 4.921 -4.362 1.00 0.00 C +ATOM 113 CG TYR 13 -11.489 4.658 -5.860 1.00 0.00 C +ATOM 114 CD1 TYR 13 -12.707 5.003 -6.504 1.00 0.00 C +ATOM 115 CE1 TYR 13 -12.920 4.729 -7.883 1.00 0.00 C +ATOM 116 CD2 TYR 13 -10.495 4.032 -6.638 1.00 0.00 C +ATOM 117 CE2 TYR 13 -10.698 3.753 -8.020 1.00 0.00 C +ATOM 118 CZ TYR 13 -11.911 4.105 -8.630 1.00 0.00 C +ATOM 119 OH TYR 13 -12.113 3.839 -9.965 1.00 0.00 O +ATOM 120 HH TYR 13 -11.339 3.412 -10.341 1.00 0.00 H +ATOM 121 C TYR 13 -11.204 6.559 -2.392 1.00 0.00 C +ATOM 122 O TYR 13 -10.159 6.886 -1.825 1.00 0.00 O +ATOM 123 N ASN 14 -12.381 6.424 -1.749 1.00 0.00 N +ATOM 124 H ASN 14 -13.200 6.300 -2.258 1.00 0.00 H +ATOM 125 CA ASN 14 -12.543 6.540 -0.276 1.00 0.00 C +ATOM 126 CB ASN 14 -13.129 7.905 0.104 1.00 0.00 C +ATOM 127 CG ASN 14 -12.963 8.238 1.590 1.00 0.00 C +ATOM 128 OD1 ASN 14 -13.822 7.910 2.408 1.00 0.00 O +ATOM 129 ND2 ASN 14 -11.862 8.897 1.934 1.00 0.00 N +ATOM 130 HD21 ASN 14 -11.215 9.135 1.238 1.00 0.00 H +ATOM 131 HD22 ASN 14 -11.741 9.120 2.880 1.00 0.00 H +ATOM 132 C ASN 14 -13.346 5.404 0.412 1.00 0.00 C +ATOM 133 O ASN 14 -14.469 5.088 0.008 1.00 0.00 O +ATOM 134 N ASP 15 -12.760 4.844 1.487 1.00 0.00 N +ATOM 135 H ASP 15 -11.889 5.166 1.772 1.00 0.00 H +ATOM 136 CA ASP 15 -13.300 3.743 2.335 1.00 0.00 C +ATOM 137 CB ASP 15 -14.386 4.251 3.305 1.00 0.00 C +ATOM 138 CG ASP 15 -13.810 4.975 4.512 1.00 0.00 C +ATOM 139 OD1 ASP 15 -13.564 6.198 4.425 1.00 0.00 O +ATOM 140 OD2 ASP 15 -13.619 4.321 5.558 1.00 0.00 O +ATOM 141 C ASP 15 -13.760 2.437 1.653 1.00 0.00 C +ATOM 142 O ASP 15 -14.424 2.478 0.614 1.00 0.00 O +ATOM 143 N VAL 16 -13.458 1.301 2.300 1.00 0.00 N +ATOM 144 H VAL 16 -12.991 1.376 3.164 1.00 0.00 H +ATOM 145 CA VAL 16 -13.769 -0.076 1.833 1.00 0.00 C +ATOM 146 CB VAL 16 -13.187 -1.164 2.820 1.00 0.00 C +ATOM 147 CG1 VAL 16 -11.684 -1.273 2.647 1.00 0.00 C +ATOM 148 CG2 VAL 16 -13.512 -0.842 4.291 1.00 0.00 C +ATOM 149 C VAL 16 -15.233 -0.419 1.435 1.00 0.00 C +ATOM 150 O VAL 16 -16.124 0.417 1.601 1.00 0.00 O +ATOM 151 N PHE 17 -15.443 -1.646 0.921 1.00 0.00 N +ATOM 152 H PHE 17 -14.667 -2.245 0.838 1.00 0.00 H +ATOM 153 CA PHE 17 -16.732 -2.218 0.448 1.00 0.00 C +ATOM 154 CB PHE 17 -16.582 -3.762 0.264 1.00 0.00 C +ATOM 155 CG PHE 17 -15.951 -4.503 1.453 1.00 0.00 C +ATOM 156 CD1 PHE 17 -14.545 -4.610 1.581 1.00 0.00 C +ATOM 157 CD2 PHE 17 -16.763 -5.129 2.426 1.00 0.00 C +ATOM 158 CE1 PHE 17 -13.956 -5.327 2.659 1.00 0.00 C +ATOM 159 CE2 PHE 17 -16.189 -5.849 3.511 1.00 0.00 C +ATOM 160 CZ PHE 17 -14.782 -5.948 3.626 1.00 0.00 C +ATOM 161 C PHE 17 -18.055 -1.891 1.194 1.00 0.00 C +ATOM 162 O PHE 17 -18.028 -1.250 2.251 1.00 0.00 O +ATOM 163 N TYR 18 -19.187 -2.354 0.632 1.00 0.00 N +ATOM 164 H TYR 18 -19.121 -2.870 -0.203 1.00 0.00 H +ATOM 165 CA TYR 18 -20.562 -2.158 1.156 1.00 0.00 C +ATOM 166 CB TYR 18 -21.574 -3.043 0.375 1.00 0.00 C +ATOM 167 CG TYR 18 -21.231 -4.533 0.192 1.00 0.00 C +ATOM 168 CD1 TYR 18 -21.656 -5.502 1.134 1.00 0.00 C +ATOM 169 CE1 TYR 18 -21.369 -6.884 0.953 1.00 0.00 C +ATOM 170 CD2 TYR 18 -20.508 -4.984 -0.941 1.00 0.00 C +ATOM 171 CE2 TYR 18 -20.217 -6.364 -1.130 1.00 0.00 C +ATOM 172 CZ TYR 18 -20.651 -7.302 -0.179 1.00 0.00 C +ATOM 173 OH TYR 18 -20.373 -8.638 -0.356 1.00 0.00 O +ATOM 174 HH TYR 18 -19.879 -8.772 -1.169 1.00 0.00 H +ATOM 175 C TYR 18 -20.742 -2.346 2.677 1.00 0.00 C +ATOM 176 O TYR 18 -21.530 -1.627 3.300 1.00 0.00 O +ATOM 177 N SER 19 -19.991 -3.301 3.244 1.00 0.00 N +ATOM 178 H SER 19 -19.390 -3.850 2.695 1.00 0.00 H +ATOM 179 CA SER 19 -19.990 -3.612 4.684 1.00 0.00 C +ATOM 180 CB SER 19 -20.151 -5.122 4.919 1.00 0.00 C +ATOM 181 OG SER 19 -19.228 -5.878 4.155 1.00 0.00 O +ATOM 182 HG SER 19 -19.383 -5.748 3.216 1.00 0.00 H +ATOM 183 C SER 19 -18.671 -3.102 5.285 1.00 0.00 C +ATOM 184 O SER 19 -17.664 -3.026 4.571 1.00 0.00 O +ATOM 185 N ASP 20 -18.686 -2.760 6.587 1.00 0.00 N +ATOM 186 H ASP 20 -19.517 -2.867 7.099 1.00 0.00 H +ATOM 187 CA ASP 20 -17.541 -2.217 7.377 1.00 0.00 C +ATOM 188 CB ASP 20 -16.631 -3.342 7.969 1.00 0.00 C +ATOM 189 CG ASP 20 -16.008 -4.255 6.905 1.00 0.00 C +ATOM 190 OD1 ASP 20 -14.898 -3.942 6.423 1.00 0.00 O +ATOM 191 OD2 ASP 20 -16.626 -5.287 6.568 1.00 0.00 O +ATOM 192 C ASP 20 -16.730 -1.053 6.740 1.00 0.00 C +ATOM 193 O ASP 20 -15.606 -0.748 7.165 1.00 0.00 O +ATOM 194 N GLY 21 -17.349 -0.394 5.754 1.00 0.00 N +ATOM 195 H GLY 21 -18.255 -0.644 5.466 1.00 0.00 H +ATOM 196 CA GLY 21 -16.734 0.724 5.049 1.00 0.00 C +ATOM 197 C GLY 21 -17.700 1.415 4.101 1.00 0.00 C +ATOM 198 O GLY 21 -18.880 1.047 4.051 1.00 0.00 O +ATOM 199 N ALA 22 -17.197 2.409 3.357 1.00 0.00 N +ATOM 200 H ALA 22 -16.249 2.620 3.451 1.00 0.00 H +ATOM 201 CA ALA 22 -17.990 3.190 2.396 1.00 0.00 C +ATOM 202 CB ALA 22 -18.023 4.677 2.805 1.00 0.00 C +ATOM 203 C ALA 22 -17.537 3.026 0.928 1.00 0.00 C +ATOM 204 O ALA 22 -16.788 3.853 0.391 1.00 0.00 O +ATOM 205 N LYS 23 -17.986 1.918 0.314 1.00 0.00 N +ATOM 206 H LYS 23 -18.537 1.279 0.819 1.00 0.00 H +ATOM 207 CA LYS 23 -17.750 1.502 -1.095 1.00 0.00 C +ATOM 208 CB LYS 23 -18.828 2.095 -2.025 1.00 0.00 C +ATOM 209 CG LYS 23 -20.228 1.524 -1.826 1.00 0.00 C +ATOM 210 CD LYS 23 -21.229 2.164 -2.781 1.00 0.00 C +ATOM 211 CE LYS 23 -22.639 1.605 -2.599 1.00 0.00 C +ATOM 212 NZ LYS 23 -22.778 0.181 -3.030 1.00 0.00 N +ATOM 213 HZ1 LYS 23 -23.758 -0.132 -2.879 1.00 0.00 H +ATOM 214 HZ2 LYS 23 -22.133 -0.414 -2.472 1.00 0.00 H +ATOM 215 HZ3 LYS 23 -22.539 0.099 -4.039 1.00 0.00 H +ATOM 216 C LYS 23 -16.383 1.599 -1.811 1.00 0.00 C +ATOM 217 O LYS 23 -15.853 0.570 -2.247 1.00 0.00 O +ATOM 218 N THR 24 -15.825 2.816 -1.921 1.00 0.00 N +ATOM 219 H THR 24 -16.267 3.583 -1.495 1.00 0.00 H +ATOM 220 CA THR 24 -14.566 3.080 -2.652 1.00 0.00 C +ATOM 221 CB THR 24 -14.602 4.510 -3.285 1.00 0.00 C +ATOM 222 OG1 THR 24 -15.075 5.461 -2.328 1.00 0.00 O +ATOM 223 HG1 THR 24 -14.344 5.689 -1.774 1.00 0.00 H +ATOM 224 CG2 THR 24 -15.537 4.529 -4.490 1.00 0.00 C +ATOM 225 C THR 24 -13.172 2.639 -2.098 1.00 0.00 C +ATOM 226 O THR 24 -12.914 1.437 -2.114 1.00 0.00 O +ATOM 227 N GLY 25 -12.299 3.545 -1.621 1.00 0.00 N +ATOM 228 H GLY 25 -12.529 4.481 -1.661 1.00 0.00 H +ATOM 229 CA GLY 25 -10.974 3.136 -1.130 1.00 0.00 C +ATOM 230 C GLY 25 -10.240 3.745 0.070 1.00 0.00 C +ATOM 231 O GLY 25 -10.237 3.152 1.153 1.00 0.00 O +ATOM 232 N VAL 26 -9.575 4.892 -0.162 1.00 0.00 N +ATOM 233 H VAL 26 -9.605 5.223 -1.082 1.00 0.00 H +ATOM 234 CA VAL 26 -8.762 5.732 0.776 1.00 0.00 C +ATOM 235 CB VAL 26 -9.604 6.404 1.975 1.00 0.00 C +ATOM 236 CG1 VAL 26 -9.889 5.426 3.135 1.00 0.00 C +ATOM 237 CG2 VAL 26 -8.949 7.691 2.479 1.00 0.00 C +ATOM 238 C VAL 26 -7.312 5.323 1.180 1.00 0.00 C +ATOM 239 O VAL 26 -7.069 4.707 2.230 1.00 0.00 O +ATOM 240 N PHE 27 -6.394 5.608 0.251 1.00 0.00 N +ATOM 241 H PHE 27 -6.698 5.995 -0.603 1.00 0.00 H +ATOM 242 CA PHE 27 -4.938 5.418 0.345 1.00 0.00 C +ATOM 243 CG PHE 27 -4.639 4.183 -1.918 1.00 0.00 C +ATOM 244 CD1 PHE 27 -5.937 3.608 -1.970 1.00 0.00 C +ATOM 245 CD2 PHE 27 -3.610 3.572 -2.660 1.00 0.00 C +ATOM 246 CE1 PHE 27 -6.196 2.438 -2.740 1.00 0.00 C +ATOM 247 CE2 PHE 27 -3.848 2.401 -3.436 1.00 0.00 C +ATOM 248 CZ PHE 27 -5.147 1.832 -3.473 1.00 0.00 C +ATOM 249 C PHE 27 -4.260 6.472 1.248 1.00 0.00 C +ATOM 250 O PHE 27 -3.273 6.175 1.929 1.00 0.00 O +ATOM 251 CB PHE 27 -4.322 5.420 -1.070 1.00 0.00 C +ATOM 252 N VAL 28 -4.827 7.690 1.249 1.00 0.00 N +ATOM 253 H VAL 28 -5.654 7.816 0.729 1.00 0.00 H +ATOM 254 CA VAL 28 -4.312 8.869 1.982 1.00 0.00 C +ATOM 255 CB VAL 28 -5.128 10.178 1.596 1.00 0.00 C +ATOM 256 CG1 VAL 28 -6.447 10.286 2.361 1.00 0.00 C +ATOM 257 CG2 VAL 28 -4.266 11.443 1.745 1.00 0.00 C +ATOM 258 C VAL 28 -4.098 8.761 3.517 1.00 0.00 C +ATOM 259 O VAL 28 -3.121 9.322 4.018 1.00 0.00 O +ATOM 260 N VAL 29 -4.978 8.052 4.240 1.00 0.00 N +ATOM 261 H VAL 29 -5.733 7.618 3.784 1.00 0.00 H +ATOM 262 CA VAL 29 -4.856 7.888 5.710 1.00 0.00 C +ATOM 263 CB VAL 29 -6.167 7.307 6.366 1.00 0.00 C +ATOM 264 CG1 VAL 29 -7.218 8.400 6.471 1.00 0.00 C +ATOM 265 CG2 VAL 29 -6.737 6.119 5.563 1.00 0.00 C +ATOM 266 C VAL 29 -3.604 7.079 6.118 1.00 0.00 C +ATOM 267 O VAL 29 -2.834 7.515 6.989 1.00 0.00 O +ATOM 268 N GLU 30 -3.385 5.946 5.432 1.00 0.00 N +ATOM 269 H GLU 30 -4.032 5.674 4.747 1.00 0.00 H +ATOM 270 CA GLU 30 -2.216 5.074 5.650 1.00 0.00 C +ATOM 271 CB GLU 30 -2.371 3.674 5.001 1.00 0.00 C +ATOM 272 CG GLU 30 -3.262 3.547 3.753 1.00 0.00 C +ATOM 273 CD GLU 30 -4.555 2.803 4.029 1.00 0.00 C +ATOM 274 OE1 GLU 30 -4.567 1.560 3.903 1.00 0.00 O +ATOM 275 OE2 GLU 30 -5.561 3.459 4.369 1.00 0.00 O +ATOM 276 C GLU 30 -0.957 5.795 5.163 1.00 0.00 C +ATOM 277 O GLU 30 0.090 5.690 5.792 1.00 0.00 O +ATOM 278 N ALA 31 -1.096 6.554 4.067 1.00 0.00 N +ATOM 279 H ALA 31 -1.965 6.598 3.606 1.00 0.00 H +ATOM 280 CA ALA 31 -0.013 7.353 3.462 1.00 0.00 C +ATOM 281 CB ALA 31 -0.434 7.851 2.089 1.00 0.00 C +ATOM 282 C ALA 31 0.389 8.538 4.359 1.00 0.00 C +ATOM 283 O ALA 31 1.579 8.853 4.464 1.00 0.00 O +ATOM 284 N LEU 32 -0.609 9.149 5.024 1.00 0.00 N +ATOM 285 H LEU 32 -1.526 8.817 4.938 1.00 0.00 H +ATOM 286 CA LEU 32 -0.422 10.299 5.934 1.00 0.00 C +ATOM 287 CB LEU 32 -1.762 11.011 6.250 1.00 0.00 C +ATOM 288 CG LEU 32 -1.765 12.544 6.468 1.00 0.00 C +ATOM 289 CD1 LEU 32 -2.555 13.257 5.372 1.00 0.00 C +ATOM 290 CD2 LEU 32 -2.322 12.892 7.849 1.00 0.00 C +ATOM 291 C LEU 32 0.337 9.926 7.223 1.00 0.00 C +ATOM 292 O LEU 32 1.137 10.737 7.707 1.00 0.00 O +ATOM 293 N HIS 33 0.091 8.719 7.763 1.00 0.00 N +ATOM 294 H HIS 33 -0.591 8.125 7.364 1.00 0.00 H +ATOM 295 CA HIS 33 0.785 8.238 8.977 1.00 0.00 C +ATOM 296 CB HIS 33 0.153 6.942 9.526 1.00 0.00 C +ATOM 297 CG HIS 33 -1.159 7.146 10.228 1.00 0.00 C +ATOM 298 CD2 HIS 33 -1.558 6.815 11.480 1.00 0.00 C +ATOM 299 ND1 HIS 33 -2.249 7.741 9.628 1.00 0.00 N +ATOM 300 HD1 HIS 33 -2.265 8.118 8.727 1.00 0.00 H +ATOM 301 CE1 HIS 33 -3.261 7.768 10.477 1.00 0.00 C +ATOM 302 NE2 HIS 33 -2.867 7.213 11.608 1.00 0.00 N +ATOM 303 HE2 HIS 33 -3.420 7.102 12.410 1.00 0.00 H +ATOM 304 C HIS 33 2.300 8.077 8.660 1.00 0.00 C +ATOM 305 O HIS 33 3.122 8.564 9.445 1.00 0.00 O +ATOM 306 N PRO 34 2.694 7.410 7.517 1.00 0.00 N +ATOM 307 CD PRO 34 2.006 6.372 6.722 1.00 0.00 C +ATOM 308 CA PRO 34 4.130 7.298 7.218 1.00 0.00 C +ATOM 309 CB PRO 34 4.164 6.341 6.032 1.00 0.00 C +ATOM 310 CG PRO 34 3.122 5.410 6.375 1.00 0.00 C +ATOM 311 C PRO 34 4.728 8.673 6.863 1.00 0.00 C +ATOM 312 O PRO 34 5.870 8.953 7.218 1.00 0.00 O +ATOM 313 N PHE 35 3.919 9.522 6.208 1.00 0.00 N +ATOM 314 H PHE 35 3.006 9.227 5.988 1.00 0.00 H +ATOM 315 CA PHE 35 4.285 10.892 5.775 1.00 0.00 C +ATOM 316 CB PHE 35 3.072 11.534 5.041 1.00 0.00 C +ATOM 317 CG PHE 35 3.419 12.602 3.999 1.00 0.00 C +ATOM 318 CD1 PHE 35 3.521 13.966 4.364 1.00 0.00 C +ATOM 319 CD2 PHE 35 3.559 12.259 2.632 1.00 0.00 C +ATOM 320 CE1 PHE 35 3.756 14.975 3.388 1.00 0.00 C +ATOM 321 CE2 PHE 35 3.794 13.255 1.643 1.00 0.00 C +ATOM 322 CZ PHE 35 3.892 14.617 2.023 1.00 0.00 C +ATOM 323 C PHE 35 4.698 11.770 6.978 1.00 0.00 C +ATOM 324 O PHE 35 5.754 12.407 6.928 1.00 0.00 O +ATOM 325 N ASN 36 3.901 11.748 8.060 1.00 0.00 N +ATOM 326 H ASN 36 3.088 11.197 8.065 1.00 0.00 H +ATOM 327 CA ASN 36 4.179 12.527 9.285 1.00 0.00 C +ATOM 328 CB ASN 36 2.923 12.698 10.179 1.00 0.00 C +ATOM 329 CG ASN 36 2.263 11.372 10.587 1.00 0.00 C +ATOM 330 OD1 ASN 36 2.882 10.512 11.222 1.00 0.00 O +ATOM 331 ND2 ASN 36 0.978 11.242 10.277 1.00 0.00 N +ATOM 332 HD21 ASN 36 0.534 10.406 10.530 1.00 0.00 H +ATOM 333 HD22 ASN 36 0.519 11.972 9.810 1.00 0.00 H +ATOM 334 C ASN 36 5.394 12.042 10.099 1.00 0.00 C +ATOM 335 O ASN 36 6.201 12.867 10.549 1.00 0.00 O +ATOM 336 N THR 37 5.534 10.714 10.246 1.00 0.00 N +ATOM 337 H THR 37 4.862 10.103 9.853 1.00 0.00 H +ATOM 338 CA THR 37 6.658 10.104 10.990 1.00 0.00 C +ATOM 339 CB THR 37 6.392 8.592 11.367 1.00 0.00 C +ATOM 340 OG1 THR 37 7.469 8.096 12.174 1.00 0.00 O +ATOM 341 HG1 THR 37 8.293 8.116 11.681 1.00 0.00 H +ATOM 342 CG2 THR 37 6.233 7.707 10.141 1.00 0.00 C +ATOM 343 C THR 37 8.005 10.324 10.257 1.00 0.00 C +ATOM 344 O THR 37 9.029 10.572 10.903 1.00 0.00 O +ATOM 345 N PHE 38 7.975 10.220 8.919 1.00 0.00 N +ATOM 346 H PHE 38 7.136 9.978 8.468 1.00 0.00 H +ATOM 347 CA PHE 38 9.137 10.447 8.035 1.00 0.00 C +ATOM 348 CB PHE 38 8.892 9.871 6.619 1.00 0.00 C +ATOM 349 CG PHE 38 9.298 8.406 6.449 1.00 0.00 C +ATOM 350 CD1 PHE 38 10.617 8.061 6.065 1.00 0.00 C +ATOM 351 CD2 PHE 38 8.361 7.362 6.641 1.00 0.00 C +ATOM 352 CE1 PHE 38 10.996 6.704 5.876 1.00 0.00 C +ATOM 353 CE2 PHE 38 8.726 6.001 6.455 1.00 0.00 C +ATOM 354 CZ PHE 38 10.048 5.672 6.072 1.00 0.00 C +ATOM 355 C PHE 38 9.546 11.931 7.963 1.00 0.00 C +ATOM 356 O PHE 38 10.741 12.239 7.880 1.00 0.00 O +ATOM 357 N ARG 39 8.545 12.829 8.000 1.00 0.00 N +ATOM 358 H ARG 39 7.613 12.514 8.047 1.00 0.00 H +ATOM 359 CA ARG 39 8.734 14.298 7.963 1.00 0.00 C +ATOM 360 CB ARG 39 7.389 15.030 7.870 1.00 0.00 C +ATOM 361 CG ARG 39 6.915 15.322 6.453 1.00 0.00 C +ATOM 362 CD ARG 39 5.640 16.166 6.434 1.00 0.00 C +ATOM 363 NE ARG 39 4.472 15.455 6.966 1.00 0.00 N +ATOM 364 HE ARG 39 4.558 14.491 7.119 1.00 0.00 H +ATOM 365 CZ ARG 39 3.298 16.017 7.259 1.00 0.00 C +ATOM 366 NH1 ARG 39 2.315 15.266 7.735 1.00 0.00 N +ATOM 367 HH11 ARG 39 2.456 14.285 7.873 1.00 0.00 H +ATOM 368 HH12 ARG 39 1.432 15.679 7.957 1.00 0.00 H +ATOM 369 NH2 ARG 39 3.095 17.319 7.081 1.00 0.00 N +ATOM 370 HH21 ARG 39 3.829 17.895 6.722 1.00 0.00 H +ATOM 371 HH22 ARG 39 2.207 17.721 7.307 1.00 0.00 H +ATOM 372 C ARG 39 9.501 14.818 9.187 1.00 0.00 C +ATOM 373 O ARG 39 10.386 15.668 9.042 1.00 0.00 O +ATOM 374 N LYS 40 9.149 14.307 10.378 1.00 0.00 N +ATOM 375 H LYS 40 8.407 13.658 10.445 1.00 0.00 H +ATOM 376 CA LYS 40 9.801 14.683 11.647 1.00 0.00 C +ATOM 377 CB LYS 40 8.943 14.335 12.888 1.00 0.00 C +ATOM 378 CG LYS 40 8.396 12.907 13.031 1.00 0.00 C +ATOM 379 CD LYS 40 7.852 12.701 14.444 1.00 0.00 C +ATOM 380 CE LYS 40 7.195 11.340 14.632 1.00 0.00 C +ATOM 381 NZ LYS 40 5.847 11.258 13.999 1.00 0.00 N +ATOM 382 HZ1 LYS 40 5.449 10.309 14.151 1.00 0.00 H +ATOM 383 HZ2 LYS 40 5.221 11.969 14.428 1.00 0.00 H +ATOM 384 HZ3 LYS 40 5.930 11.443 12.980 1.00 0.00 H +ATOM 385 C LYS 40 11.261 14.201 11.796 1.00 0.00 C +ATOM 386 O LYS 40 12.081 14.909 12.388 1.00 0.00 O +ATOM 387 N GLU 41 11.563 13.013 11.248 1.00 0.00 N +ATOM 388 H GLU 41 10.860 12.508 10.782 1.00 0.00 H +ATOM 389 CA GLU 41 12.906 12.384 11.286 1.00 0.00 C +ATOM 390 CB GLU 41 12.856 10.952 10.711 1.00 0.00 C +ATOM 391 CG GLU 41 12.133 9.910 11.582 1.00 0.00 C +ATOM 392 CD GLU 41 13.084 8.974 12.324 1.00 0.00 C +ATOM 393 OE1 GLU 41 13.346 9.219 13.521 1.00 0.00 O +ATOM 394 OE2 GLU 41 13.566 7.999 11.709 1.00 0.00 O +ATOM 395 C GLU 41 14.031 13.177 10.592 1.00 0.00 C +ATOM 396 O GLU 41 15.119 13.325 11.159 1.00 0.00 O +ATOM 397 N GLY 42 13.759 13.674 9.380 1.00 0.00 N +ATOM 398 H GLY 42 12.884 13.533 8.957 1.00 0.00 H +ATOM 399 CA GLY 42 14.743 14.447 8.630 1.00 0.00 C +ATOM 400 C GLY 42 14.811 14.109 7.153 1.00 0.00 C +ATOM 401 O GLY 42 15.712 14.592 6.455 1.00 0.00 O +ATOM 402 N PHE 43 13.865 13.287 6.686 1.00 0.00 N +ATOM 403 H PHE 43 13.182 12.948 7.303 1.00 0.00 H +ATOM 404 CA PHE 43 13.785 12.855 5.281 1.00 0.00 C +ATOM 405 CB PHE 43 13.831 11.303 5.173 1.00 0.00 C +ATOM 406 CG PHE 43 14.868 10.632 6.077 1.00 0.00 C +ATOM 407 CD1 PHE 43 14.469 10.009 7.282 1.00 0.00 C +ATOM 408 CD2 PHE 43 16.242 10.615 5.732 1.00 0.00 C +ATOM 409 CE1 PHE 43 15.418 9.381 8.134 1.00 0.00 C +ATOM 410 CE2 PHE 43 17.203 9.991 6.575 1.00 0.00 C +ATOM 411 CZ PHE 43 16.789 9.373 7.779 1.00 0.00 C +ATOM 412 C PHE 43 12.515 13.413 4.622 1.00 0.00 C +ATOM 413 O PHE 43 11.433 13.379 5.224 1.00 0.00 O +ATOM 414 N GLU 44 12.670 13.940 3.399 1.00 0.00 N +ATOM 415 H GLU 44 13.560 13.960 2.988 1.00 0.00 H +ATOM 416 CA GLU 44 11.582 14.540 2.600 1.00 0.00 C +ATOM 417 CB GLU 44 12.155 15.547 1.592 1.00 0.00 C +ATOM 418 CG GLU 44 12.673 16.842 2.212 1.00 0.00 C +ATOM 419 CD GLU 44 13.145 17.843 1.173 1.00 0.00 C +ATOM 420 OE1 GLU 44 12.317 18.651 0.702 1.00 0.00 O +ATOM 421 OE2 GLU 44 14.346 17.825 0.831 1.00 0.00 O +ATOM 422 C GLU 44 10.689 13.515 1.874 1.00 0.00 C +ATOM 423 O GLU 44 11.193 12.530 1.321 1.00 0.00 O +ATOM 424 N VAL 45 9.369 13.745 1.930 1.00 0.00 N +ATOM 425 H VAL 45 9.022 14.528 2.412 1.00 0.00 H +ATOM 426 CA VAL 45 8.342 12.887 1.302 1.00 0.00 C +ATOM 427 CG1 VAL 45 8.048 11.086 3.071 1.00 0.00 C +ATOM 428 CG2 VAL 45 6.923 13.266 3.423 1.00 0.00 C +ATOM 429 C VAL 45 7.536 13.629 0.212 1.00 0.00 C +ATOM 430 O VAL 45 7.238 14.822 0.363 1.00 0.00 O +ATOM 431 CB VAL 45 7.364 12.241 2.367 1.00 0.00 C +ATOM 432 N ASP 46 7.221 12.917 -0.879 1.00 0.00 N +ATOM 433 H ASP 46 7.496 11.979 -0.943 1.00 0.00 H +ATOM 434 CA ASP 46 6.455 13.441 -2.027 1.00 0.00 C +ATOM 435 CB ASP 46 7.365 13.545 -3.275 1.00 0.00 C +ATOM 436 CG ASP 46 6.893 14.602 -4.277 1.00 0.00 C +ATOM 437 OD1 ASP 46 6.103 14.258 -5.183 1.00 0.00 O +ATOM 438 OD2 ASP 46 7.326 15.770 -4.165 1.00 0.00 O +ATOM 439 C ASP 46 5.286 12.473 -2.301 1.00 0.00 C +ATOM 440 O ASP 46 5.453 11.254 -2.164 1.00 0.00 O +ATOM 441 N PHE 47 4.117 13.022 -2.667 1.00 0.00 N +ATOM 442 H PHE 47 4.027 13.997 -2.738 1.00 0.00 H +ATOM 443 CA PHE 47 2.911 12.230 -2.983 1.00 0.00 C +ATOM 444 CB PHE 47 1.689 12.662 -2.115 1.00 0.00 C +ATOM 445 CG PHE 47 1.447 14.174 -2.021 1.00 0.00 C +ATOM 446 CD1 PHE 47 0.456 14.792 -2.819 1.00 0.00 C +ATOM 447 CD2 PHE 47 2.163 14.973 -1.097 1.00 0.00 C +ATOM 448 CE1 PHE 47 0.178 16.181 -2.700 1.00 0.00 C +ATOM 449 CE2 PHE 47 1.897 16.364 -0.967 1.00 0.00 C +ATOM 450 CZ PHE 47 0.901 16.969 -1.771 1.00 0.00 C +ATOM 451 C PHE 47 2.579 12.269 -4.485 1.00 0.00 C +ATOM 452 O PHE 47 2.478 13.352 -5.077 1.00 0.00 O +ATOM 453 N VAL 48 2.439 11.077 -5.083 1.00 0.00 N +ATOM 454 H VAL 48 2.524 10.249 -4.561 1.00 0.00 H +ATOM 455 CA VAL 48 2.155 10.889 -6.522 1.00 0.00 C +ATOM 456 CB VAL 48 3.436 10.424 -7.319 1.00 0.00 C +ATOM 457 CG1 VAL 48 4.458 11.551 -7.362 1.00 0.00 C +ATOM 458 CG2 VAL 48 4.086 9.168 -6.699 1.00 0.00 C +ATOM 459 C VAL 48 0.943 9.974 -6.822 1.00 0.00 C +ATOM 460 O VAL 48 0.691 9.020 -6.081 1.00 0.00 O +ATOM 461 N SER 49 0.188 10.299 -7.882 1.00 0.00 N +ATOM 462 H SER 49 0.415 11.082 -8.430 1.00 0.00 H +ATOM 463 CA SER 49 -1.004 9.537 -8.303 1.00 0.00 C +ATOM 464 CB SER 49 -2.193 10.481 -8.481 1.00 0.00 C +ATOM 465 OG SER 49 -3.409 9.771 -8.659 1.00 0.00 O +ATOM 466 HG SER 49 -4.131 10.394 -8.767 1.00 0.00 H +ATOM 467 C SER 49 -0.775 8.767 -9.612 1.00 0.00 C +ATOM 468 O SER 49 -0.014 9.227 -10.469 1.00 0.00 O +ATOM 469 N GLU 50 -1.509 7.654 -9.780 1.00 0.00 N +ATOM 470 H GLU 50 -2.147 7.400 -9.075 1.00 0.00 H +ATOM 471 CA GLU 50 -1.452 6.744 -10.954 1.00 0.00 C +ATOM 472 CB GLU 50 -2.503 5.636 -10.818 1.00 0.00 C +ATOM 473 CG GLU 50 -2.291 4.708 -9.621 1.00 0.00 C +ATOM 474 CD GLU 50 -3.405 3.695 -9.456 1.00 0.00 C +ATOM 475 OE1 GLU 50 -4.453 4.044 -8.871 1.00 0.00 O +ATOM 476 OE2 GLU 50 -3.229 2.544 -9.902 1.00 0.00 O +ATOM 477 C GLU 50 -1.599 7.446 -12.318 1.00 0.00 C +ATOM 478 O GLU 50 -1.092 6.957 -13.337 1.00 0.00 O +ATOM 479 N THR 51 -2.282 8.599 -12.300 1.00 0.00 N +ATOM 480 H THR 51 -2.667 8.932 -11.459 1.00 0.00 H +ATOM 481 CA THR 51 -2.528 9.461 -13.471 1.00 0.00 C +ATOM 482 CB THR 51 -4.060 9.605 -13.760 1.00 0.00 C +ATOM 483 OG1 THR 51 -4.756 9.929 -12.549 1.00 0.00 O +ATOM 484 HG1 THR 51 -4.466 10.780 -12.211 1.00 0.00 H +ATOM 485 CG2 THR 51 -4.623 8.314 -14.342 1.00 0.00 C +ATOM 486 C THR 51 -1.910 10.838 -13.158 1.00 0.00 C +ATOM 487 O THR 51 -1.259 10.990 -12.117 1.00 0.00 O +ATOM 488 N GLY 52 -2.107 11.824 -14.043 1.00 0.00 N +ATOM 489 H GLY 52 -2.619 11.664 -14.866 1.00 0.00 H +ATOM 490 CA GLY 52 -1.581 13.173 -13.839 1.00 0.00 C +ATOM 491 C GLY 52 -2.359 13.960 -12.792 1.00 0.00 C +ATOM 492 O GLY 52 -1.950 15.062 -12.413 1.00 0.00 O +ATOM 493 N LYS 53 -3.487 13.382 -12.355 1.00 0.00 N +ATOM 494 H LYS 53 -3.750 12.516 -12.733 1.00 0.00 H +ATOM 495 CA LYS 53 -4.381 13.954 -11.332 1.00 0.00 C +ATOM 496 CB LYS 53 -5.746 14.383 -11.926 1.00 0.00 C +ATOM 497 CG LYS 53 -6.443 13.390 -12.883 1.00 0.00 C +ATOM 498 CD LYS 53 -7.771 13.945 -13.386 1.00 0.00 C +ATOM 499 CE LYS 53 -8.478 12.979 -14.335 1.00 0.00 C +ATOM 500 NZ LYS 53 -8.978 11.741 -13.663 1.00 0.00 N +ATOM 501 HZ1 LYS 53 -9.658 12.001 -12.920 1.00 0.00 H +ATOM 502 HZ2 LYS 53 -9.446 11.132 -14.364 1.00 0.00 H +ATOM 503 HZ3 LYS 53 -8.178 11.230 -13.238 1.00 0.00 H +ATOM 504 C LYS 53 -4.567 12.997 -10.140 1.00 0.00 C +ATOM 505 O LYS 53 -4.519 11.774 -10.319 1.00 0.00 O +ATOM 506 N PHE 54 -4.790 13.564 -8.945 1.00 0.00 N +ATOM 507 H PHE 54 -4.828 14.542 -8.862 1.00 0.00 H +ATOM 508 CA PHE 54 -4.990 12.808 -7.692 1.00 0.00 C +ATOM 509 CB PHE 54 -4.477 13.619 -6.483 1.00 0.00 C +ATOM 510 CG PHE 54 -3.303 12.989 -5.738 1.00 0.00 C +ATOM 511 CD1 PHE 54 -3.513 12.244 -4.558 1.00 0.00 C +ATOM 512 CD2 PHE 54 -1.975 13.193 -6.170 1.00 0.00 C +ATOM 513 CE1 PHE 54 -2.420 11.717 -3.820 1.00 0.00 C +ATOM 514 CE2 PHE 54 -0.879 12.674 -5.444 1.00 0.00 C +ATOM 515 CZ PHE 54 -1.102 11.933 -4.266 1.00 0.00 C +ATOM 516 C PHE 54 -6.450 12.418 -7.465 1.00 0.00 C +ATOM 517 O PHE 54 -6.730 11.449 -6.752 1.00 0.00 O +ATOM 518 N GLY 55 -7.361 13.201 -8.051 1.00 0.00 N +ATOM 519 H GLY 55 -7.096 13.983 -8.583 1.00 0.00 H +ATOM 520 CA GLY 55 -8.794 12.953 -7.941 1.00 0.00 C +ATOM 521 C GLY 55 -9.479 13.508 -6.704 1.00 0.00 C +ATOM 522 O GLY 55 -9.285 14.679 -6.361 1.00 0.00 O +ATOM 523 N TRP 56 -10.301 12.664 -6.068 1.00 0.00 N +ATOM 524 H TRP 56 -10.419 11.759 -6.428 1.00 0.00 H +ATOM 525 CA TRP 56 -11.055 12.993 -4.849 1.00 0.00 C +ATOM 526 CB TRP 56 -12.569 13.119 -5.143 1.00 0.00 C +ATOM 527 CG TRP 56 -12.981 14.236 -6.133 1.00 0.00 C +ATOM 528 CD2 TRP 56 -13.056 14.152 -7.575 1.00 0.00 C +ATOM 529 CE2 TRP 56 -13.519 15.415 -8.043 1.00 0.00 C +ATOM 530 CE3 TRP 56 -12.778 13.135 -8.519 1.00 0.00 C +ATOM 531 CD1 TRP 56 -13.391 15.510 -5.810 1.00 0.00 C +ATOM 532 NE1 TRP 56 -13.712 16.212 -6.946 1.00 0.00 N +ATOM 533 HE1 TRP 56 -14.029 17.139 -6.962 1.00 0.00 H +ATOM 534 CZ2 TRP 56 -13.714 15.694 -9.418 1.00 0.00 C +ATOM 535 CZ3 TRP 56 -12.972 13.413 -9.896 1.00 0.00 C +ATOM 536 CH2 TRP 56 -13.436 14.687 -10.325 1.00 0.00 C +ATOM 537 C TRP 56 -10.878 11.890 -3.812 1.00 0.00 C +ATOM 538 O TRP 56 -10.600 10.743 -4.170 1.00 0.00 O +ATOM 539 N ASP 57 -11.024 12.254 -2.532 1.00 0.00 N +ATOM 540 H ASP 57 -11.195 13.192 -2.293 1.00 0.00 H +ATOM 541 CA ASP 57 -10.944 11.317 -1.403 1.00 0.00 C +ATOM 542 CB ASP 57 -9.913 11.792 -0.367 1.00 0.00 C +ATOM 543 CG ASP 57 -9.442 10.677 0.561 1.00 0.00 C +ATOM 544 OD1 ASP 57 -9.888 10.652 1.726 1.00 0.00 O +ATOM 545 OD2 ASP 57 -8.616 9.839 0.133 1.00 0.00 O +ATOM 546 C ASP 57 -12.372 11.277 -0.827 1.00 0.00 C +ATOM 547 O ASP 57 -12.579 10.975 0.356 1.00 0.00 O +ATOM 548 N GLU 58 -13.337 11.610 -1.702 1.00 0.00 N +ATOM 549 H GLU 58 -13.090 11.873 -2.616 1.00 0.00 H +ATOM 550 CA GLU 58 -14.803 11.639 -1.470 1.00 0.00 C +ATOM 551 CB GLU 58 -15.416 10.272 -1.829 1.00 0.00 C +ATOM 552 CG GLU 58 -15.520 10.010 -3.329 1.00 0.00 C +ATOM 553 CD GLU 58 -16.170 8.679 -3.651 1.00 0.00 C +ATOM 554 OE1 GLU 58 -17.416 8.624 -3.731 1.00 0.00 O +ATOM 555 OE2 GLU 58 -15.434 7.688 -3.832 1.00 0.00 O +ATOM 556 C GLU 58 -15.378 12.148 -0.128 1.00 0.00 C +ATOM 557 O GLU 58 -14.635 12.353 0.838 1.00 0.00 O +ATOM 558 N HIS 59 -16.700 12.376 -0.105 1.00 0.00 N +ATOM 559 H HIS 59 -17.243 12.233 -0.912 1.00 0.00 H +ATOM 560 CA HIS 59 -17.438 12.844 1.079 1.00 0.00 C +ATOM 561 CB HIS 59 -18.456 13.932 0.684 1.00 0.00 C +ATOM 562 CG HIS 59 -17.840 15.193 0.147 1.00 0.00 C +ATOM 563 CD2 HIS 59 -17.811 15.711 -1.106 1.00 0.00 C +ATOM 564 ND1 HIS 59 -17.173 16.097 0.947 1.00 0.00 N +ATOM 565 HD1 HIS 59 -17.024 16.006 1.911 1.00 0.00 H +ATOM 566 CE1 HIS 59 -16.760 17.115 0.213 1.00 0.00 C +ATOM 567 NE2 HIS 59 -17.134 16.905 -1.036 1.00 0.00 N +ATOM 568 HE2 HIS 59 -16.958 17.504 -1.792 1.00 0.00 H +ATOM 569 C HIS 59 -18.120 11.633 1.756 1.00 0.00 C +ATOM 570 O HIS 59 -19.239 11.730 2.285 1.00 0.00 O +ATOM 571 N SER 60 -17.389 10.507 1.757 1.00 0.00 N +ATOM 572 H SER 60 -16.493 10.518 1.351 1.00 0.00 H +ATOM 573 CA SER 60 -17.809 9.214 2.335 1.00 0.00 C +ATOM 574 CB SER 60 -16.937 8.089 1.761 1.00 0.00 C +ATOM 575 OG SER 60 -17.062 8.016 0.352 1.00 0.00 O +ATOM 576 HG SER 60 -16.508 7.306 0.017 1.00 0.00 H +ATOM 577 C SER 60 -17.728 9.216 3.876 1.00 0.00 C +ATOM 578 O SER 60 -18.272 8.320 4.538 1.00 0.00 O +ATOM 579 N LEU 61 -17.079 10.256 4.418 1.00 0.00 N +ATOM 580 H LEU 61 -16.689 10.952 3.845 1.00 0.00 H +ATOM 581 CA LEU 61 -16.888 10.462 5.863 1.00 0.00 C +ATOM 582 CB LEU 61 -15.402 10.746 6.165 1.00 0.00 C +ATOM 583 CG LEU 61 -14.407 9.608 6.429 1.00 0.00 C +ATOM 584 CD1 LEU 61 -13.573 9.269 5.189 1.00 0.00 C +ATOM 585 CD2 LEU 61 -13.486 10.053 7.554 1.00 0.00 C +ATOM 586 C LEU 61 -17.761 11.608 6.405 1.00 0.00 C +ATOM 587 O LEU 61 -18.233 12.446 5.629 1.00 0.00 O +ATOM 588 N ALA 62 -17.958 11.627 7.736 1.00 0.00 N +ATOM 589 H ALA 62 -17.552 10.926 8.292 1.00 0.00 H +ATOM 590 CA ALA 62 -18.752 12.623 8.505 1.00 0.00 C +ATOM 591 CB ALA 62 -18.142 14.046 8.388 1.00 0.00 C +ATOM 592 C ALA 62 -20.273 12.666 8.256 1.00 0.00 C +ATOM 593 O ALA 62 -21.050 12.486 9.202 1.00 0.00 O +ATOM 594 N LYS 63 -20.680 12.899 7.000 1.00 0.00 N +ATOM 595 H LYS 63 -20.026 13.033 6.281 1.00 0.00 H +ATOM 596 CA LYS 63 -22.101 12.979 6.602 1.00 0.00 C +ATOM 597 CB LYS 63 -22.365 14.241 5.761 1.00 0.00 C +ATOM 598 CG LYS 63 -22.251 15.555 6.526 1.00 0.00 C +ATOM 599 CD LYS 63 -22.527 16.750 5.620 1.00 0.00 C +ATOM 600 CE LYS 63 -22.417 18.078 6.367 1.00 0.00 C +ATOM 601 NZ LYS 63 -21.024 18.416 6.785 1.00 0.00 N +ATOM 602 HZ1 LYS 63 -20.415 18.481 5.944 1.00 0.00 H +ATOM 603 HZ2 LYS 63 -21.023 19.327 7.286 1.00 0.00 H +ATOM 604 HZ3 LYS 63 -20.662 17.673 7.417 1.00 0.00 H +ATOM 605 C LYS 63 -22.607 11.724 5.867 1.00 0.00 C +ATOM 606 O LYS 63 -23.462 11.008 6.401 1.00 0.00 O +ATOM 607 N ASP 64 -22.058 11.460 4.665 1.00 0.00 N +ATOM 608 H ASP 64 -21.368 12.066 4.316 1.00 0.00 H +ATOM 609 CA ASP 64 -22.376 10.318 3.757 1.00 0.00 C +ATOM 610 CB ASP 64 -21.368 9.143 3.944 1.00 0.00 C +ATOM 611 CG ASP 64 -21.283 8.632 5.388 1.00 0.00 C +ATOM 612 OD1 ASP 64 -20.447 9.153 6.158 1.00 0.00 O +ATOM 613 OD2 ASP 64 -22.043 7.704 5.741 1.00 0.00 O +ATOM 614 C ASP 64 -23.840 9.802 3.623 1.00 0.00 C +ATOM 615 O ASP 64 -24.080 8.735 3.038 1.00 0.00 O +ATOM 616 N PHE 65 -24.803 10.599 4.120 1.00 0.00 N +ATOM 617 H PHE 65 -24.565 11.463 4.519 1.00 0.00 H +ATOM 618 CA PHE 65 -26.268 10.325 4.118 1.00 0.00 C +ATOM 619 CB PHE 65 -26.870 10.399 2.683 1.00 0.00 C +ATOM 620 CG PHE 65 -26.759 11.768 2.012 1.00 0.00 C +ATOM 621 CD1 PHE 65 -27.792 12.726 2.145 1.00 0.00 C +ATOM 622 CD2 PHE 65 -25.638 12.092 1.210 1.00 0.00 C +ATOM 623 CE1 PHE 65 -27.714 13.988 1.492 1.00 0.00 C +ATOM 624 CE2 PHE 65 -25.546 13.350 0.550 1.00 0.00 C +ATOM 625 CZ PHE 65 -26.587 14.299 0.693 1.00 0.00 C +ATOM 626 C PHE 65 -26.724 9.025 4.815 1.00 0.00 C +ATOM 627 O PHE 65 -25.996 8.025 4.804 1.00 0.00 O +ATOM 628 N LEU 66 -27.928 9.058 5.405 1.00 0.00 N +ATOM 629 H LEU 66 -28.471 9.875 5.379 1.00 0.00 H +ATOM 630 CA LEU 66 -28.527 7.914 6.120 1.00 0.00 C +ATOM 631 CB LEU 66 -29.238 8.384 7.419 1.00 0.00 C +ATOM 632 CG LEU 66 -30.226 9.568 7.572 1.00 0.00 C +ATOM 633 CD1 LEU 66 -31.678 9.162 7.265 1.00 0.00 C +ATOM 634 CD2 LEU 66 -30.138 10.086 8.999 1.00 0.00 C +ATOM 635 C LEU 66 -29.459 7.044 5.248 1.00 0.00 C +ATOM 636 O LEU 66 -29.283 5.822 5.189 1.00 0.00 O +ATOM 637 N ASN 67 -30.417 7.694 4.561 1.00 0.00 N +ATOM 638 H ASN 67 -30.482 8.671 4.641 1.00 0.00 H +ATOM 639 CA ASN 67 -31.433 7.089 3.655 1.00 0.00 C +ATOM 640 CB ASN 67 -30.793 6.499 2.378 1.00 0.00 C +ATOM 641 CG ASN 67 -30.133 7.557 1.502 1.00 0.00 C +ATOM 642 OD1 ASN 67 -30.766 8.126 0.610 1.00 0.00 O +ATOM 643 ND2 ASN 67 -28.849 7.813 1.743 1.00 0.00 N +ATOM 644 HD21 ASN 67 -28.410 8.491 1.189 1.00 0.00 H +ATOM 645 HD22 ASN 67 -28.389 7.322 2.457 1.00 0.00 H +ATOM 646 C ASN 67 -32.421 6.076 4.262 1.00 0.00 C +ATOM 647 O ASN 67 -33.619 6.131 3.963 1.00 0.00 O +ATOM 648 N GLY 68 -31.914 5.168 5.102 1.00 0.00 N +ATOM 649 H GLY 68 -30.966 5.134 5.324 1.00 0.00 H +ATOM 650 CA GLY 68 -32.745 4.155 5.739 1.00 0.00 C +ATOM 651 C GLY 68 -32.236 3.739 7.108 1.00 0.00 C +ATOM 652 O GLY 68 -31.505 4.500 7.754 1.00 0.00 O +ATOM 653 N GLN 69 -32.628 2.533 7.539 1.00 0.00 N +ATOM 654 H GLN 69 -33.205 1.989 6.961 1.00 0.00 H +ATOM 655 CA GLN 69 -32.247 1.953 8.839 1.00 0.00 C +ATOM 656 CB GLN 69 -33.489 1.440 9.587 1.00 0.00 C +ATOM 657 CG GLN 69 -34.436 2.530 10.077 1.00 0.00 C +ATOM 658 CD GLN 69 -35.642 1.971 10.807 1.00 0.00 C +ATOM 659 OE1 GLN 69 -36.679 1.703 10.199 1.00 0.00 O +ATOM 660 NE2 GLN 69 -35.513 1.791 12.117 1.00 0.00 N +ATOM 661 HE21 GLN 69 -34.665 2.021 12.553 1.00 0.00 H +ATOM 662 HE22 GLN 69 -36.284 1.430 12.602 1.00 0.00 H +ATOM 663 C GLN 69 -31.223 0.814 8.690 1.00 0.00 C +ATOM 664 O GLN 69 -30.474 0.524 9.633 1.00 0.00 O +ATOM 665 N ASP 70 -31.184 0.203 7.497 1.00 0.00 N +ATOM 666 H ASP 70 -31.784 0.489 6.773 1.00 0.00 H +ATOM 667 CA ASP 70 -30.276 -0.913 7.164 1.00 0.00 C +ATOM 668 CB ASP 70 -30.977 -1.915 6.232 1.00 0.00 C +ATOM 669 CG ASP 70 -32.152 -2.626 6.898 1.00 0.00 C +ATOM 670 OD1 ASP 70 -33.291 -2.117 6.809 1.00 0.00 O +ATOM 671 OD2 ASP 70 -31.940 -3.704 7.497 1.00 0.00 O +ATOM 672 C ASP 70 -28.959 -0.441 6.522 1.00 0.00 C +ATOM 673 O ASP 70 -27.909 -1.057 6.739 1.00 0.00 O +ATOM 674 N GLU 71 -29.031 0.663 5.765 1.00 0.00 N +ATOM 675 H GLU 71 -29.898 1.115 5.659 1.00 0.00 H +ATOM 676 CA GLU 71 -27.889 1.286 5.057 1.00 0.00 C +ATOM 677 CB GLU 71 -28.383 2.343 4.061 1.00 0.00 C +ATOM 678 CG GLU 71 -29.101 1.774 2.839 1.00 0.00 C +ATOM 679 CD GLU 71 -29.607 2.851 1.899 1.00 0.00 C +ATOM 680 OE1 GLU 71 -28.843 3.272 1.005 1.00 0.00 O +ATOM 681 OE2 GLU 71 -30.773 3.273 2.052 1.00 0.00 O +ATOM 682 C GLU 71 -26.839 1.902 5.999 1.00 0.00 C +ATOM 683 O GLU 71 -25.637 1.829 5.718 1.00 0.00 O +ATOM 684 N THR 72 -27.311 2.483 7.114 1.00 0.00 N +ATOM 685 H THR 72 -28.285 2.482 7.262 1.00 0.00 H +ATOM 686 CA THR 72 -26.471 3.126 8.150 1.00 0.00 C +ATOM 687 CB THR 72 -27.337 3.835 9.235 1.00 0.00 C +ATOM 688 OG1 THR 72 -28.343 2.934 9.719 1.00 0.00 O +ATOM 689 HG1 THR 72 -27.939 2.180 10.155 1.00 0.00 H +ATOM 690 CG2 THR 72 -28.001 5.084 8.667 1.00 0.00 C +ATOM 691 C THR 72 -25.502 2.130 8.825 1.00 0.00 C +ATOM 692 O THR 72 -24.355 2.486 9.129 1.00 0.00 O +ATOM 693 N ASP 73 -25.974 0.889 9.026 1.00 0.00 N +ATOM 694 H ASP 73 -26.895 0.676 8.755 1.00 0.00 H +ATOM 695 CA ASP 73 -25.205 -0.216 9.636 1.00 0.00 C +ATOM 696 CG ASP 73 -27.140 -1.042 11.085 1.00 0.00 C +ATOM 697 OD1 ASP 73 -26.826 -1.242 12.280 1.00 0.00 O +ATOM 698 OD2 ASP 73 -28.254 -0.583 10.748 1.00 0.00 O +ATOM 699 C ASP 73 -24.060 -0.703 8.724 1.00 0.00 C +ATOM 700 O ASP 73 -22.940 -0.917 9.202 1.00 0.00 O +ATOM 701 CB ASP 73 -26.132 -1.391 9.995 1.00 0.00 C +ATOM 702 N PHE 74 -24.364 -0.876 7.427 1.00 0.00 N +ATOM 703 H PHE 74 -25.280 -0.700 7.118 1.00 0.00 H +ATOM 704 CA PHE 74 -23.407 -1.319 6.391 1.00 0.00 C +ATOM 705 CB PHE 74 -24.149 -1.772 5.109 1.00 0.00 C +ATOM 706 CG PHE 74 -24.790 -3.157 5.197 1.00 0.00 C +ATOM 707 CD1 PHE 74 -26.130 -3.312 5.625 1.00 0.00 C +ATOM 708 CD2 PHE 74 -24.069 -4.314 4.814 1.00 0.00 C +ATOM 709 CE1 PHE 74 -26.745 -4.594 5.671 1.00 0.00 C +ATOM 710 CE2 PHE 74 -24.669 -5.603 4.855 1.00 0.00 C +ATOM 711 CZ PHE 74 -26.011 -5.742 5.285 1.00 0.00 C +ATOM 712 C PHE 74 -22.316 -0.294 6.029 1.00 0.00 C +ATOM 713 O PHE 74 -21.166 -0.678 5.789 1.00 0.00 O +ATOM 714 N LYS 75 -22.685 0.997 6.015 1.00 0.00 N +ATOM 715 H LYS 75 -23.616 1.237 6.230 1.00 0.00 H +ATOM 716 CA LYS 75 -21.776 2.120 5.685 1.00 0.00 C +ATOM 717 CB LYS 75 -22.565 3.425 5.513 1.00 0.00 C +ATOM 718 CG LYS 75 -23.347 3.524 4.209 1.00 0.00 C +ATOM 719 CD LYS 75 -24.083 4.855 4.105 1.00 0.00 C +ATOM 720 CE LYS 75 -24.841 4.995 2.786 1.00 0.00 C +ATOM 721 NZ LYS 75 -26.004 4.066 2.663 1.00 0.00 N +ATOM 722 HZ1 LYS 75 -26.471 4.215 1.745 1.00 0.00 H +ATOM 723 HZ2 LYS 75 -25.671 3.083 2.726 1.00 0.00 H +ATOM 724 HZ3 LYS 75 -26.681 4.253 3.430 1.00 0.00 H +ATOM 725 C LYS 75 -20.630 2.335 6.690 1.00 0.00 C +ATOM 726 O LYS 75 -19.509 2.664 6.286 1.00 0.00 O +ATOM 727 N ASN 76 -20.925 2.150 7.990 1.00 0.00 N +ATOM 728 H ASN 76 -21.841 1.902 8.244 1.00 0.00 H +ATOM 729 CA ASN 76 -19.985 2.282 9.139 1.00 0.00 C +ATOM 730 CB ASN 76 -19.042 1.057 9.224 1.00 0.00 C +ATOM 731 CG ASN 76 -19.765 -0.214 9.649 1.00 0.00 C +ATOM 732 OD1 ASN 76 -20.281 -0.959 8.813 1.00 0.00 O +ATOM 733 ND2 ASN 76 -19.793 -0.475 10.953 1.00 0.00 N +ATOM 734 HD21 ASN 76 -19.358 0.146 11.575 1.00 0.00 H +ATOM 735 HD22 ASN 76 -20.255 -1.289 11.243 1.00 0.00 H +ATOM 736 C ASN 76 -19.183 3.597 9.314 1.00 0.00 C +ATOM 737 O ASN 76 -18.601 3.830 10.383 1.00 0.00 O +ATOM 738 N LYS 77 -19.209 4.464 8.286 1.00 0.00 N +ATOM 739 H LYS 77 -19.730 4.275 7.484 1.00 0.00 H +ATOM 740 CA LYS 77 -18.517 5.781 8.216 1.00 0.00 C +ATOM 741 CB LYS 77 -19.166 6.832 9.148 1.00 0.00 C +ATOM 742 CG LYS 77 -20.587 7.231 8.769 1.00 0.00 C +ATOM 743 CD LYS 77 -21.149 8.267 9.737 1.00 0.00 C +ATOM 744 CE LYS 77 -22.573 8.682 9.375 1.00 0.00 C +ATOM 745 NZ LYS 77 -23.581 7.599 9.577 1.00 0.00 N +ATOM 746 HZ1 LYS 77 -23.586 7.312 10.577 1.00 0.00 H +ATOM 747 HZ2 LYS 77 -23.336 6.781 8.983 1.00 0.00 H +ATOM 748 HZ3 LYS 77 -24.524 7.949 9.313 1.00 0.00 H +ATOM 749 C LYS 77 -16.983 5.768 8.398 1.00 0.00 C +ATOM 750 O LYS 77 -16.254 6.078 7.449 1.00 0.00 O +ATOM 751 N ASP 78 -16.518 5.388 9.605 1.00 0.00 N +ATOM 752 H ASP 78 -17.157 5.153 10.310 1.00 0.00 H +ATOM 753 CA ASP 78 -15.092 5.292 10.033 1.00 0.00 C +ATOM 754 CB ASP 78 -14.605 3.811 10.031 1.00 0.00 C +ATOM 755 CG ASP 78 -14.780 3.111 8.679 1.00 0.00 C +ATOM 756 OD1 ASP 78 -13.807 3.081 7.896 1.00 0.00 O +ATOM 757 OD2 ASP 78 -15.880 2.579 8.412 1.00 0.00 O +ATOM 758 C ASP 78 -14.047 6.275 9.422 1.00 0.00 C +ATOM 759 O ASP 78 -14.421 7.383 9.020 1.00 0.00 O +ATOM 760 N SER 79 -12.762 5.872 9.371 1.00 0.00 N +ATOM 761 H SER 79 -12.499 4.995 9.717 1.00 0.00 H +ATOM 762 CA SER 79 -11.611 6.650 8.835 1.00 0.00 C +ATOM 763 CB SER 79 -11.709 6.841 7.306 1.00 0.00 C +ATOM 764 OG SER 79 -11.573 5.604 6.630 1.00 0.00 O +ATOM 765 HG SER 79 -11.637 5.747 5.683 1.00 0.00 H +ATOM 766 C SER 79 -11.305 7.986 9.557 1.00 0.00 C +ATOM 767 O SER 79 -11.968 8.310 10.549 1.00 0.00 O +ATOM 768 N ASP 80 -10.312 8.736 9.055 1.00 0.00 N +ATOM 769 H ASP 80 -9.832 8.442 8.250 1.00 0.00 H +ATOM 770 CA ASP 80 -9.867 10.017 9.638 1.00 0.00 C +ATOM 771 CB ASP 80 -8.326 10.104 9.600 1.00 0.00 C +ATOM 772 CG ASP 80 -7.650 9.072 10.498 1.00 0.00 C +ATOM 773 OD1 ASP 80 -7.356 7.956 10.014 1.00 0.00 O +ATOM 774 OD2 ASP 80 -7.396 9.381 11.683 1.00 0.00 O +ATOM 775 C ASP 80 -10.485 11.318 9.077 1.00 0.00 C +ATOM 776 O ASP 80 -11.261 11.977 9.780 1.00 0.00 O +ATOM 777 N PHE 81 -10.141 11.671 7.828 1.00 0.00 N +ATOM 778 H PHE 81 -9.545 11.092 7.304 1.00 0.00 H +ATOM 779 CA PHE 81 -10.601 12.902 7.148 1.00 0.00 C +ATOM 780 CB PHE 81 -9.391 13.848 6.877 1.00 0.00 C +ATOM 781 CG PHE 81 -8.033 13.146 6.808 1.00 0.00 C +ATOM 782 CD1 PHE 81 -7.172 13.144 7.930 1.00 0.00 C +ATOM 783 CD2 PHE 81 -7.615 12.474 5.635 1.00 0.00 C +ATOM 784 CE1 PHE 81 -5.918 12.480 7.890 1.00 0.00 C +ATOM 785 CE2 PHE 81 -6.364 11.806 5.582 1.00 0.00 C +ATOM 786 CZ PHE 81 -5.516 11.808 6.712 1.00 0.00 C +ATOM 787 C PHE 81 -11.377 12.661 5.841 1.00 0.00 C +ATOM 788 O PHE 81 -11.441 11.527 5.357 1.00 0.00 O +ATOM 789 N ASN 82 -11.926 13.749 5.274 1.00 0.00 N +ATOM 790 H ASN 82 -11.805 14.627 5.700 1.00 0.00 H +ATOM 791 CA ASN 82 -12.713 13.757 4.024 1.00 0.00 C +ATOM 792 CB ASN 82 -13.736 14.909 4.074 1.00 0.00 C +ATOM 793 CG ASN 82 -14.990 14.635 3.255 1.00 0.00 C +ATOM 794 OD1 ASN 82 -15.042 14.929 2.059 1.00 0.00 O +ATOM 795 ND2 ASN 82 -16.015 14.088 3.904 1.00 0.00 N +ATOM 796 HD21 ASN 82 -16.838 13.912 3.408 1.00 0.00 H +ATOM 797 HD22 ASN 82 -15.916 13.879 4.857 1.00 0.00 H +ATOM 798 C ASN 82 -11.792 13.907 2.790 1.00 0.00 C +ATOM 799 O ASN 82 -11.858 13.088 1.868 1.00 0.00 O +ATOM 800 N LYS 83 -10.942 14.951 2.803 1.00 0.00 N +ATOM 801 H LYS 83 -10.947 15.561 3.573 1.00 0.00 H +ATOM 802 CA LYS 83 -9.956 15.312 1.750 1.00 0.00 C +ATOM 803 CB LYS 83 -8.678 14.465 1.872 1.00 0.00 C +ATOM 804 CG LYS 83 -7.700 15.002 2.905 1.00 0.00 C +ATOM 805 CD LYS 83 -6.328 14.356 2.775 1.00 0.00 C +ATOM 806 CE LYS 83 -5.287 15.054 3.647 1.00 0.00 C +ATOM 807 NZ LYS 83 -5.507 14.876 5.114 1.00 0.00 N +ATOM 808 HZ1 LYS 83 -4.768 15.387 5.638 1.00 0.00 H +ATOM 809 HZ2 LYS 83 -6.441 15.253 5.374 1.00 0.00 H +ATOM 810 HZ3 LYS 83 -5.460 13.866 5.351 1.00 0.00 H +ATOM 811 C LYS 83 -10.387 15.412 0.270 1.00 0.00 C +ATOM 812 O LYS 83 -11.313 14.716 -0.162 1.00 0.00 O +ATOM 813 N THR 84 -9.699 16.291 -0.477 1.00 0.00 N +ATOM 814 H THR 84 -8.974 16.819 -0.076 1.00 0.00 H +ATOM 815 CA THR 84 -9.940 16.554 -1.911 1.00 0.00 C +ATOM 816 CB THR 84 -10.141 18.105 -2.197 1.00 0.00 C +ATOM 817 OG1 THR 84 -10.270 18.337 -3.607 1.00 0.00 O +ATOM 818 HG1 THR 84 -11.045 17.885 -3.947 1.00 0.00 H +ATOM 819 CG2 THR 84 -8.991 18.966 -1.623 1.00 0.00 C +ATOM 820 C THR 84 -8.852 15.949 -2.832 1.00 0.00 C +ATOM 821 O THR 84 -9.139 15.607 -3.985 1.00 0.00 O +ATOM 822 N LEU 85 -7.622 15.816 -2.301 1.00 0.00 N +ATOM 823 H LEU 85 -7.470 16.092 -1.371 1.00 0.00 H +ATOM 824 CA LEU 85 -6.411 15.274 -2.986 1.00 0.00 C +ATOM 825 CB LEU 85 -6.588 13.776 -3.389 1.00 0.00 C +ATOM 826 CG LEU 85 -6.794 12.648 -2.361 1.00 0.00 C +ATOM 827 CD1 LEU 85 -7.388 11.456 -3.087 1.00 0.00 C +ATOM 828 CD2 LEU 85 -5.514 12.234 -1.614 1.00 0.00 C +ATOM 829 C LEU 85 -5.915 16.125 -4.184 1.00 0.00 C +ATOM 830 O LEU 85 -6.705 16.445 -5.083 1.00 0.00 O +ATOM 831 N ALA 86 -4.622 16.492 -4.171 1.00 0.00 N +ATOM 832 H ALA 86 -4.037 16.207 -3.436 1.00 0.00 H +ATOM 833 CA ALA 86 -3.988 17.324 -5.219 1.00 0.00 C +ATOM 834 CB ALA 86 -3.450 18.610 -4.616 1.00 0.00 C +ATOM 835 C ALA 86 -2.890 16.622 -6.037 1.00 0.00 C +ATOM 836 O ALA 86 -1.958 16.041 -5.469 1.00 0.00 O +ATOM 837 N LYS 87 -3.000 16.749 -7.368 1.00 0.00 N +ATOM 838 H LYS 87 -3.744 17.291 -7.717 1.00 0.00 H +ATOM 839 CA LYS 87 -2.120 16.159 -8.413 1.00 0.00 C +ATOM 840 CB LYS 87 -2.479 16.762 -9.789 1.00 0.00 C +ATOM 841 CG LYS 87 -2.618 18.297 -9.864 1.00 0.00 C +ATOM 842 CD LYS 87 -2.973 18.753 -11.275 1.00 0.00 C +ATOM 843 CE LYS 87 -3.115 20.271 -11.373 1.00 0.00 C +ATOM 844 NZ LYS 87 -4.304 20.807 -10.645 1.00 0.00 N +ATOM 845 HZ1 LYS 87 -5.170 20.388 -11.039 1.00 0.00 H +ATOM 846 HZ2 LYS 87 -4.339 21.841 -10.753 1.00 0.00 H +ATOM 847 HZ3 LYS 87 -4.231 20.566 -9.636 1.00 0.00 H +ATOM 848 C LYS 87 -0.576 16.020 -8.268 1.00 0.00 C +ATOM 849 O LYS 87 -0.102 15.069 -7.638 1.00 0.00 O +ATOM 850 N ILE 88 0.173 16.951 -8.889 1.00 0.00 N +ATOM 851 H ILE 88 -0.242 17.691 -9.373 1.00 0.00 H +ATOM 852 CA ILE 88 1.658 17.057 -8.939 1.00 0.00 C +ATOM 853 CB ILE 88 2.361 17.124 -7.492 1.00 0.00 C +ATOM 854 CG2 ILE 88 3.908 17.294 -7.621 1.00 0.00 C +ATOM 855 CG1 ILE 88 1.789 18.311 -6.691 1.00 0.00 C +ATOM 856 CD1 ILE 88 1.827 18.165 -5.162 1.00 0.00 C +ATOM 857 C ILE 88 2.408 16.138 -9.951 1.00 0.00 C +ATOM 858 O ILE 88 2.584 16.549 -11.105 1.00 0.00 O +ATOM 859 N LYS 89 2.833 14.928 -9.540 1.00 0.00 N +ATOM 860 H LYS 89 2.619 14.622 -8.633 1.00 0.00 H +ATOM 861 CA LYS 89 3.622 14.009 -10.401 1.00 0.00 C +ATOM 862 CB LYS 89 5.106 14.060 -9.970 1.00 0.00 C +ATOM 863 CG LYS 89 5.865 15.315 -10.392 1.00 0.00 C +ATOM 864 CD LYS 89 7.304 15.289 -9.889 1.00 0.00 C +ATOM 865 CE LYS 89 8.082 16.537 -10.300 1.00 0.00 C +ATOM 866 NZ LYS 89 7.617 17.783 -9.619 1.00 0.00 N +ATOM 867 HZ1 LYS 89 7.723 17.675 -8.590 1.00 0.00 H +ATOM 868 HZ2 LYS 89 8.187 18.589 -9.944 1.00 0.00 H +ATOM 869 HZ3 LYS 89 6.616 17.950 -9.848 1.00 0.00 H +ATOM 870 C LYS 89 3.205 12.522 -10.559 1.00 0.00 C +ATOM 871 O LYS 89 2.147 12.103 -10.078 1.00 0.00 O +ATOM 872 N THR 90 4.072 11.775 -11.274 1.00 0.00 N +ATOM 873 H THR 90 4.842 12.238 -11.677 1.00 0.00 H +ATOM 874 CA THR 90 4.058 10.322 -11.623 1.00 0.00 C +ATOM 875 CB THR 90 5.538 9.755 -11.498 1.00 0.00 C +ATOM 876 OG1 THR 90 5.561 8.329 -11.647 1.00 0.00 O +ATOM 877 HG1 THR 90 6.464 8.013 -11.568 1.00 0.00 H +ATOM 878 CG2 THR 90 6.205 10.141 -10.167 1.00 0.00 C +ATOM 879 C THR 90 3.048 9.293 -10.997 1.00 0.00 C +ATOM 880 O THR 90 2.533 9.557 -9.914 1.00 0.00 O +ATOM 881 N PRO 91 2.678 8.168 -11.707 1.00 0.00 N +ATOM 882 CD PRO 91 2.228 7.126 -10.752 1.00 0.00 C +ATOM 883 CA PRO 91 2.915 7.507 -13.012 1.00 0.00 C +ATOM 884 CB PRO 91 2.056 6.257 -12.901 1.00 0.00 C +ATOM 885 CG PRO 91 2.356 5.827 -11.543 1.00 0.00 C +ATOM 886 C PRO 91 2.598 8.332 -14.273 1.00 0.00 C +ATOM 887 O PRO 91 2.049 9.435 -14.166 1.00 0.00 O +ATOM 888 N LYS 92 2.986 7.792 -15.446 1.00 0.00 N +ATOM 889 H LYS 92 3.421 6.910 -15.442 1.00 0.00 H +ATOM 890 CA LYS 92 2.840 8.372 -16.815 1.00 0.00 C +ATOM 891 CB LYS 92 1.427 8.935 -17.098 1.00 0.00 C +ATOM 892 CG LYS 92 0.322 7.886 -17.139 1.00 0.00 C +ATOM 893 CD LYS 92 -1.030 8.520 -17.422 1.00 0.00 C +ATOM 894 CE LYS 92 -2.132 7.473 -17.463 1.00 0.00 C +ATOM 895 NZ LYS 92 -3.464 8.080 -17.739 1.00 0.00 N +ATOM 896 HZ1 LYS 92 -3.440 8.564 -18.659 1.00 0.00 H +ATOM 897 HZ2 LYS 92 -4.188 7.333 -17.759 1.00 0.00 H +ATOM 898 HZ3 LYS 92 -3.694 8.766 -16.992 1.00 0.00 H +ATOM 899 C LYS 92 3.922 9.424 -17.134 1.00 0.00 C +ATOM 900 O LYS 92 4.286 9.612 -18.303 1.00 0.00 O +ATOM 901 N GLU 93 4.432 10.077 -16.080 1.00 0.00 N +ATOM 902 H GLU 93 4.117 9.899 -15.171 1.00 0.00 H +ATOM 903 CA GLU 93 5.487 11.109 -16.152 1.00 0.00 C +ATOM 904 CB GLU 93 4.939 12.479 -15.704 1.00 0.00 C +ATOM 905 CG GLU 93 3.920 13.102 -16.656 1.00 0.00 C +ATOM 906 CD GLU 93 3.412 14.447 -16.172 1.00 0.00 C +ATOM 907 OE1 GLU 93 2.399 14.475 -15.441 1.00 0.00 O +ATOM 908 OE2 GLU 93 4.024 15.478 -16.524 1.00 0.00 O +ATOM 909 C GLU 93 6.652 10.678 -15.240 1.00 0.00 C +ATOM 910 O GLU 93 6.575 9.614 -14.616 1.00 0.00 O +ATOM 911 N VAL 94 7.725 11.494 -15.179 1.00 0.00 N +ATOM 912 H VAL 94 7.723 12.316 -15.717 1.00 0.00 H +ATOM 913 CA VAL 94 8.968 11.297 -14.364 1.00 0.00 C +ATOM 914 CB VAL 94 8.746 11.582 -12.794 1.00 0.00 C +ATOM 915 CG1 VAL 94 10.077 11.899 -12.084 1.00 0.00 C +ATOM 916 CG2 VAL 94 7.774 12.744 -12.579 1.00 0.00 C +ATOM 917 C VAL 94 9.694 9.935 -14.572 1.00 0.00 C +ATOM 918 O VAL 94 9.068 8.944 -14.966 1.00 0.00 O +ATOM 919 N ASN 95 11.009 9.920 -14.306 1.00 0.00 N +ATOM 920 H ASN 95 11.461 10.740 -14.009 1.00 0.00 H +ATOM 921 CA ASN 95 11.871 8.731 -14.426 1.00 0.00 C +ATOM 922 CB ASN 95 13.253 9.143 -14.966 1.00 0.00 C +ATOM 923 CG ASN 95 13.853 8.111 -15.917 1.00 0.00 C +ATOM 924 OD1 ASN 95 13.606 8.141 -17.125 1.00 0.00 O +ATOM 925 ND2 ASN 95 14.662 7.208 -15.376 1.00 0.00 N +ATOM 926 HD21 ASN 95 15.056 6.538 -15.972 1.00 0.00 H +ATOM 927 HD22 ASN 95 14.839 7.238 -14.412 1.00 0.00 H +ATOM 928 C ASN 95 12.000 8.067 -13.036 1.00 0.00 C +ATOM 929 O ASN 95 12.134 8.770 -12.025 1.00 0.00 O +ATOM 930 N ALA 96 11.937 6.728 -13.002 1.00 0.00 N +ATOM 931 H ALA 96 11.830 6.215 -13.833 1.00 0.00 H +ATOM 932 CA ALA 96 12.021 5.937 -11.761 1.00 0.00 C +ATOM 933 CB ALA 96 10.949 4.847 -11.763 1.00 0.00 C +ATOM 934 C ALA 96 13.413 5.339 -11.474 1.00 0.00 C +ATOM 935 O ALA 96 13.584 4.601 -10.492 1.00 0.00 O +ATOM 936 N ASP 97 14.403 5.700 -12.305 1.00 0.00 N +ATOM 937 H ASP 97 14.214 6.305 -13.056 1.00 0.00 H +ATOM 938 CA ASP 97 15.803 5.243 -12.170 1.00 0.00 C +ATOM 939 CB ASP 97 16.546 5.377 -13.511 1.00 0.00 C +ATOM 940 CG ASP 97 16.111 4.335 -14.536 1.00 0.00 C +ATOM 941 OD1 ASP 97 16.733 3.251 -14.589 1.00 0.00 O +ATOM 942 OD2 ASP 97 15.159 4.602 -15.303 1.00 0.00 O +ATOM 943 C ASP 97 16.528 6.041 -11.063 1.00 0.00 C +ATOM 944 O ASP 97 17.649 5.697 -10.662 1.00 0.00 O +ATOM 945 N ASP 98 15.835 7.074 -10.561 1.00 0.00 N +ATOM 946 H ASP 98 14.940 7.285 -10.907 1.00 0.00 H +ATOM 947 CA ASP 98 16.304 7.970 -9.489 1.00 0.00 C +ATOM 948 CB ASP 98 16.047 9.439 -9.876 1.00 0.00 C +ATOM 949 CG ASP 98 16.873 9.891 -11.077 1.00 0.00 C +ATOM 950 OD1 ASP 98 16.389 9.758 -12.223 1.00 0.00 O +ATOM 951 OD2 ASP 98 18.000 10.396 -10.875 1.00 0.00 O +ATOM 952 C ASP 98 15.569 7.607 -8.181 1.00 0.00 C +ATOM 953 O ASP 98 15.018 6.503 -8.084 1.00 0.00 O +ATOM 954 N TYR 99 15.571 8.518 -7.188 1.00 0.00 N +ATOM 955 H TYR 99 16.031 9.375 -7.323 1.00 0.00 H +ATOM 956 CA TYR 99 14.932 8.367 -5.848 1.00 0.00 C +ATOM 957 CB TYR 99 13.380 8.242 -5.941 1.00 0.00 C +ATOM 958 CG TYR 99 12.639 9.366 -6.677 1.00 0.00 C +ATOM 959 CD1 TYR 99 12.416 9.303 -8.075 1.00 0.00 C +ATOM 960 CE1 TYR 99 11.698 10.326 -8.756 1.00 0.00 C +ATOM 961 CD2 TYR 99 12.123 10.483 -5.976 1.00 0.00 C +ATOM 962 CE2 TYR 99 11.403 11.510 -6.648 1.00 0.00 C +ATOM 963 CZ TYR 99 11.198 11.421 -8.033 1.00 0.00 C +ATOM 964 OH TYR 99 10.502 12.415 -8.684 1.00 0.00 O +ATOM 965 HH TYR 99 10.441 12.220 -9.622 1.00 0.00 H +ATOM 966 C TYR 99 15.502 7.205 -5.012 1.00 0.00 C +ATOM 967 O TYR 99 16.002 6.224 -5.578 1.00 0.00 O +ATOM 968 N GLN 100 15.419 7.319 -3.680 1.00 0.00 N +ATOM 969 H GLN 100 15.009 8.112 -3.270 1.00 0.00 H +ATOM 970 CA GLN 100 15.925 6.291 -2.757 1.00 0.00 C +ATOM 971 CB GLN 100 16.614 6.930 -1.538 1.00 0.00 C +ATOM 972 CG GLN 100 18.020 7.452 -1.846 1.00 0.00 C +ATOM 973 CD GLN 100 18.774 7.924 -0.615 1.00 0.00 C +ATOM 974 OE1 GLN 100 18.936 9.125 -0.398 1.00 0.00 O +ATOM 975 NE2 GLN 100 19.260 6.980 0.186 1.00 0.00 N +ATOM 976 HE21 GLN 100 19.750 7.271 0.983 1.00 0.00 H +ATOM 977 HE22 GLN 100 19.115 6.037 -0.040 1.00 0.00 H +ATOM 978 C GLN 100 14.893 5.238 -2.320 1.00 0.00 C +ATOM 979 O GLN 100 15.065 4.057 -2.634 1.00 0.00 O +ATOM 980 N ILE 101 13.818 5.669 -1.641 1.00 0.00 N +ATOM 981 H ILE 101 13.700 6.627 -1.459 1.00 0.00 H +ATOM 982 CA ILE 101 12.758 4.770 -1.130 1.00 0.00 C +ATOM 983 CB ILE 101 12.783 4.668 0.455 1.00 0.00 C +ATOM 984 CG2 ILE 101 14.058 3.913 0.883 1.00 0.00 C +ATOM 985 CG1 ILE 101 12.725 6.059 1.130 1.00 0.00 C +ATOM 986 CD1 ILE 101 12.209 6.064 2.578 1.00 0.00 C +ATOM 987 C ILE 101 11.328 5.046 -1.647 1.00 0.00 C +ATOM 988 O ILE 101 10.968 6.204 -1.875 1.00 0.00 O +ATOM 989 N PHE 102 10.556 3.970 -1.870 1.00 0.00 N +ATOM 990 H PHE 102 10.913 3.068 -1.719 1.00 0.00 H +ATOM 991 CA PHE 102 9.157 4.029 -2.344 1.00 0.00 C +ATOM 992 CB PHE 102 9.000 3.252 -3.687 1.00 0.00 C +ATOM 993 CG PHE 102 7.726 3.566 -4.486 1.00 0.00 C +ATOM 994 CD1 PHE 102 7.745 4.525 -5.526 1.00 0.00 C +ATOM 995 CD2 PHE 102 6.521 2.860 -4.246 1.00 0.00 C +ATOM 996 CE1 PHE 102 6.588 4.777 -6.316 1.00 0.00 C +ATOM 997 CE2 PHE 102 5.357 3.101 -5.026 1.00 0.00 C +ATOM 998 CZ PHE 102 5.392 4.063 -6.064 1.00 0.00 C +ATOM 999 C PHE 102 8.253 3.402 -1.264 1.00 0.00 C +ATOM 1000 O PHE 102 8.601 2.366 -0.682 1.00 0.00 O +ATOM 1001 N PHE 103 7.117 4.058 -0.998 1.00 0.00 N +ATOM 1002 H PHE 103 6.906 4.898 -1.462 1.00 0.00 H +ATOM 1003 CA PHE 103 6.109 3.608 -0.022 1.00 0.00 C +ATOM 1004 CB PHE 103 6.034 4.580 1.190 1.00 0.00 C +ATOM 1005 CG PHE 103 5.773 3.910 2.540 1.00 0.00 C +ATOM 1006 CD1 PHE 103 4.510 3.347 2.855 1.00 0.00 C +ATOM 1007 CD2 PHE 103 6.786 3.880 3.524 1.00 0.00 C +ATOM 1008 CE1 PHE 103 4.263 2.766 4.129 1.00 0.00 C +ATOM 1009 CE2 PHE 103 6.554 3.304 4.804 1.00 0.00 C +ATOM 1010 CZ PHE 103 5.289 2.745 5.106 1.00 0.00 C +ATOM 1011 C PHE 103 4.768 3.602 -0.774 1.00 0.00 C +ATOM 1012 O PHE 103 4.426 4.591 -1.433 1.00 0.00 O +ATOM 1013 N ALA 104 4.051 2.473 -0.720 1.00 0.00 N +ATOM 1014 H ALA 104 4.376 1.698 -0.221 1.00 0.00 H +ATOM 1015 CA ALA 104 2.747 2.314 -1.384 1.00 0.00 C +ATOM 1016 CB ALA 104 2.796 1.168 -2.413 1.00 0.00 C +ATOM 1017 C ALA 104 1.633 2.074 -0.357 1.00 0.00 C +ATOM 1018 O ALA 104 1.758 1.196 0.506 1.00 0.00 O +ATOM 1019 N SER 105 0.574 2.889 -0.440 1.00 0.00 N +ATOM 1020 H SER 105 0.541 3.595 -1.123 1.00 0.00 H +ATOM 1021 CA SER 105 -0.603 2.818 0.445 1.00 0.00 C +ATOM 1022 CB SER 105 -1.083 4.230 0.802 1.00 0.00 C +ATOM 1023 OG SER 105 -1.204 5.045 -0.351 1.00 0.00 O +ATOM 1024 HG SER 105 -1.505 5.919 -0.095 1.00 0.00 H +ATOM 1025 C SER 105 -1.733 2.037 -0.237 1.00 0.00 C +ATOM 1026 O SER 105 -1.588 1.647 -1.402 1.00 0.00 O +ATOM 1027 N ALA 106 -2.824 1.774 0.499 1.00 0.00 N +ATOM 1028 H ALA 106 -2.873 2.064 1.436 1.00 0.00 H +ATOM 1029 CA ALA 106 -3.999 1.053 -0.017 1.00 0.00 C +ATOM 1030 CB ALA 106 -3.726 -0.434 -0.102 1.00 0.00 C +ATOM 1031 C ALA 106 -5.281 1.340 0.773 1.00 0.00 C +ATOM 1032 O ALA 106 -5.406 2.408 1.369 1.00 0.00 O +ATOM 1033 N GLY 107 -6.247 0.421 0.712 1.00 0.00 N +ATOM 1034 H GLY 107 -6.151 -0.398 0.179 1.00 0.00 H +ATOM 1035 CA GLY 107 -7.508 0.578 1.417 1.00 0.00 C +ATOM 1036 C GLY 107 -8.436 -0.555 1.032 1.00 0.00 C +ATOM 1037 O GLY 107 -8.657 -1.480 1.822 1.00 0.00 O +ATOM 1038 N HIS 108 -8.957 -0.470 -0.196 1.00 0.00 N +ATOM 1039 H HIS 108 -8.724 0.299 -0.759 1.00 0.00 H +ATOM 1040 CA HIS 108 -9.872 -1.454 -0.788 1.00 0.00 C +ATOM 1041 CB HIS 108 -11.267 -0.814 -1.001 1.00 0.00 C +ATOM 1042 CG HIS 108 -12.322 -1.759 -1.511 1.00 0.00 C +ATOM 1043 CD2 HIS 108 -13.197 -1.640 -2.539 1.00 0.00 C +ATOM 1044 ND1 HIS 108 -12.544 -3.007 -0.967 1.00 0.00 N +ATOM 1045 HD1 HIS 108 -12.067 -3.389 -0.200 1.00 0.00 H +ATOM 1046 CE1 HIS 108 -13.504 -3.617 -1.638 1.00 0.00 C +ATOM 1047 NE2 HIS 108 -13.918 -2.808 -2.597 1.00 0.00 N +ATOM 1048 HE2 HIS 108 -14.625 -3.009 -3.245 1.00 0.00 H +ATOM 1049 C HIS 108 -9.268 -1.916 -2.125 1.00 0.00 C +ATOM 1050 O HIS 108 -8.295 -1.325 -2.608 1.00 0.00 O +ATOM 1051 N GLY 109 -9.859 -2.968 -2.706 1.00 0.00 N +ATOM 1052 H GLY 109 -10.621 -3.420 -2.281 1.00 0.00 H +ATOM 1053 CA GLY 109 -9.422 -3.510 -3.987 1.00 0.00 C +ATOM 1054 C GLY 109 -10.163 -2.860 -5.143 1.00 0.00 C +ATOM 1055 O GLY 109 -10.505 -3.518 -6.132 1.00 0.00 O +ATOM 1056 N THR 110 -10.398 -1.552 -4.984 1.00 0.00 N +ATOM 1057 H THR 110 -10.075 -1.124 -4.166 1.00 0.00 H +ATOM 1058 CA THR 110 -11.082 -0.675 -5.950 1.00 0.00 C +ATOM 1059 CB THR 110 -11.708 0.576 -5.216 1.00 0.00 C +ATOM 1060 OG1 THR 110 -12.254 1.489 -6.178 1.00 0.00 O +ATOM 1061 HG1 THR 110 -12.632 2.246 -5.723 1.00 0.00 H +ATOM 1062 CG2 THR 110 -10.678 1.299 -4.322 1.00 0.00 C +ATOM 1063 C THR 110 -10.076 -0.265 -7.056 1.00 0.00 C +ATOM 1064 O THR 110 -10.454 0.321 -8.082 1.00 0.00 O +ATOM 1065 N LEU 111 -8.810 -0.645 -6.826 1.00 0.00 N +ATOM 1066 H LEU 111 -8.629 -1.128 -5.992 1.00 0.00 H +ATOM 1067 CA LEU 111 -7.658 -0.395 -7.715 1.00 0.00 C +ATOM 1068 CB LEU 111 -6.330 -0.845 -7.034 1.00 0.00 C +ATOM 1069 CG LEU 111 -6.202 -1.936 -5.945 1.00 0.00 C +ATOM 1070 CD1 LEU 111 -6.094 -3.355 -6.526 1.00 0.00 C +ATOM 1071 CD2 LEU 111 -4.983 -1.623 -5.095 1.00 0.00 C +ATOM 1072 C LEU 111 -7.848 -1.007 -9.125 1.00 0.00 C +ATOM 1073 O LEU 111 -7.623 -2.208 -9.340 1.00 0.00 O +ATOM 1074 N PHE 112 -8.319 -0.155 -10.048 1.00 0.00 N +ATOM 1075 H PHE 112 -8.481 0.781 -9.791 1.00 0.00 H +ATOM 1076 CA PHE 112 -8.618 -0.488 -11.455 1.00 0.00 C +ATOM 1077 CB PHE 112 -9.474 0.653 -12.079 1.00 0.00 C +ATOM 1078 CG PHE 112 -10.371 0.226 -13.247 1.00 0.00 C +ATOM 1079 CD1 PHE 112 -9.903 0.289 -14.582 1.00 0.00 C +ATOM 1080 CD2 PHE 112 -11.701 -0.205 -13.019 1.00 0.00 C +ATOM 1081 CE1 PHE 112 -10.742 -0.069 -15.673 1.00 0.00 C +ATOM 1082 CE2 PHE 112 -12.552 -0.567 -14.101 1.00 0.00 C +ATOM 1083 CZ PHE 112 -12.070 -0.498 -15.431 1.00 0.00 C +ATOM 1084 C PHE 112 -7.353 -0.753 -12.302 1.00 0.00 C +ATOM 1085 O PHE 112 -7.436 -1.386 -13.364 1.00 0.00 O +ATOM 1086 N ASP 113 -6.199 -0.287 -11.804 1.00 0.00 N +ATOM 1087 H ASP 113 -6.185 0.199 -10.951 1.00 0.00 H +ATOM 1088 CA ASP 113 -4.893 -0.454 -12.466 1.00 0.00 C +ATOM 1089 CB ASP 113 -4.104 0.865 -12.454 1.00 0.00 C +ATOM 1090 CG ASP 113 -4.763 1.962 -13.285 1.00 0.00 C +ATOM 1091 OD1 ASP 113 -4.451 2.070 -14.492 1.00 0.00 O +ATOM 1092 OD2 ASP 113 -5.580 2.728 -12.729 1.00 0.00 O +ATOM 1093 C ASP 113 -4.077 -1.580 -11.808 1.00 0.00 C +ATOM 1094 O ASP 113 -3.532 -2.434 -12.512 1.00 0.00 O +ATOM 1095 N TYR 114 -4.046 -1.597 -10.466 1.00 0.00 N +ATOM 1096 H TYR 114 -4.522 -0.903 -9.958 1.00 0.00 H +ATOM 1097 CA TYR 114 -3.331 -2.613 -9.664 1.00 0.00 C +ATOM 1098 CB TYR 114 -3.040 -2.078 -8.240 1.00 0.00 C +ATOM 1099 CG TYR 114 -2.009 -0.961 -8.070 1.00 0.00 C +ATOM 1100 CD1 TYR 114 -2.420 0.370 -7.826 1.00 0.00 C +ATOM 1101 CE1 TYR 114 -1.475 1.396 -7.544 1.00 0.00 C +ATOM 1102 CD2 TYR 114 -0.619 -1.241 -8.034 1.00 0.00 C +ATOM 1103 CE2 TYR 114 0.333 -0.223 -7.750 1.00 0.00 C +ATOM 1104 CZ TYR 114 -0.106 1.089 -7.507 1.00 0.00 C +ATOM 1105 OH TYR 114 0.813 2.075 -7.231 1.00 0.00 O +ATOM 1106 HH TYR 114 0.369 2.915 -7.087 1.00 0.00 H +ATOM 1107 C TYR 114 -4.199 -3.900 -9.547 1.00 0.00 C +ATOM 1108 O TYR 114 -5.430 -3.787 -9.606 1.00 0.00 O +ATOM 1109 N PRO 115 -3.595 -5.126 -9.419 1.00 0.00 N +ATOM 1110 CD PRO 115 -4.532 -6.214 -9.048 1.00 0.00 C +ATOM 1111 CA PRO 115 -2.201 -5.630 -9.358 1.00 0.00 C +ATOM 1112 CB PRO 115 -2.375 -7.058 -8.821 1.00 0.00 C +ATOM 1113 CG PRO 115 -3.736 -7.464 -9.306 1.00 0.00 C +ATOM 1114 C PRO 115 -1.393 -5.596 -10.682 1.00 0.00 C +ATOM 1115 O PRO 115 -0.158 -5.691 -10.659 1.00 0.00 O +ATOM 1116 N LYS 116 -2.107 -5.441 -11.806 1.00 0.00 N +ATOM 1117 H LYS 116 -3.085 -5.353 -11.759 1.00 0.00 H +ATOM 1118 CA LYS 116 -1.525 -5.388 -13.162 1.00 0.00 C +ATOM 1119 CB LYS 116 -2.511 -5.976 -14.185 1.00 0.00 C +ATOM 1120 CG LYS 116 -2.725 -7.483 -14.074 1.00 0.00 C +ATOM 1121 CD LYS 116 -3.714 -7.981 -15.122 1.00 0.00 C +ATOM 1122 CE LYS 116 -3.943 -9.488 -15.030 1.00 0.00 C +ATOM 1123 NZ LYS 116 -4.675 -9.906 -13.797 1.00 0.00 N +ATOM 1124 HZ1 LYS 116 -5.608 -9.448 -13.775 1.00 0.00 H +ATOM 1125 HZ2 LYS 116 -4.130 -9.623 -12.957 1.00 0.00 H +ATOM 1126 HZ3 LYS 116 -4.795 -10.939 -13.799 1.00 0.00 H +ATOM 1127 C LYS 116 -1.073 -3.955 -13.537 1.00 0.00 C +ATOM 1128 O LYS 116 -0.499 -3.274 -12.684 1.00 0.00 O +ATOM 1129 N ALA 117 -1.323 -3.504 -14.782 1.00 0.00 N +ATOM 1130 H ALA 117 -1.779 -4.065 -15.442 1.00 0.00 H +ATOM 1131 CA ALA 117 -0.951 -2.166 -15.323 1.00 0.00 C +ATOM 1132 CB ALA 117 -1.671 -1.023 -14.572 1.00 0.00 C +ATOM 1133 C ALA 117 0.568 -1.909 -15.387 1.00 0.00 C +ATOM 1134 O ALA 117 1.284 -2.178 -14.418 1.00 0.00 O +ATOM 1135 N LYS 118 1.032 -1.371 -16.523 1.00 0.00 N +ATOM 1136 H LYS 118 0.395 -1.130 -17.233 1.00 0.00 H +ATOM 1137 CA LYS 118 2.455 -1.091 -16.808 1.00 0.00 C +ATOM 1138 CB LYS 118 2.662 -0.896 -18.318 1.00 0.00 C +ATOM 1139 CG LYS 118 2.493 -2.161 -19.155 1.00 0.00 C +ATOM 1140 CD LYS 118 2.715 -1.878 -20.632 1.00 0.00 C +ATOM 1141 CE LYS 118 2.547 -3.138 -21.466 1.00 0.00 C +ATOM 1142 NZ LYS 118 2.761 -2.876 -22.916 1.00 0.00 N +ATOM 1143 HZ1 LYS 118 2.638 -3.760 -23.450 1.00 0.00 H +ATOM 1144 HZ2 LYS 118 2.071 -2.172 -23.247 1.00 0.00 H +ATOM 1145 HZ3 LYS 118 3.724 -2.513 -23.064 1.00 0.00 H +ATOM 1146 C LYS 118 3.225 0.009 -16.051 1.00 0.00 C +ATOM 1147 O LYS 118 4.318 -0.265 -15.555 1.00 0.00 O +ATOM 1148 N ASP 119 2.641 1.208 -15.909 1.00 0.00 N +ATOM 1149 H ASP 119 1.729 1.344 -16.249 1.00 0.00 H +ATOM 1150 CA ASP 119 3.301 2.363 -15.252 1.00 0.00 C +ATOM 1151 CB ASP 119 2.512 3.654 -15.535 1.00 0.00 C +ATOM 1152 CG ASP 119 2.528 4.049 -17.009 1.00 0.00 C +ATOM 1153 OD1 ASP 119 3.438 4.804 -17.418 1.00 0.00 O +ATOM 1154 OD2 ASP 119 1.620 3.620 -17.755 1.00 0.00 O +ATOM 1155 C ASP 119 3.610 2.256 -13.743 1.00 0.00 C +ATOM 1156 O ASP 119 4.749 2.526 -13.332 1.00 0.00 O +ATOM 1157 N LEU 120 2.619 1.842 -12.941 1.00 0.00 N +ATOM 1158 H LEU 120 1.745 1.629 -13.328 1.00 0.00 H +ATOM 1159 CA LEU 120 2.761 1.664 -11.479 1.00 0.00 C +ATOM 1160 CB LEU 120 1.375 1.590 -10.779 1.00 0.00 C +ATOM 1161 CG LEU 120 0.009 1.011 -11.252 1.00 0.00 C +ATOM 1162 CD1 LEU 120 -0.550 1.747 -12.482 1.00 0.00 C +ATOM 1163 CD2 LEU 120 0.065 -0.500 -11.475 1.00 0.00 C +ATOM 1164 C LEU 120 3.649 0.458 -11.123 1.00 0.00 C +ATOM 1165 O LEU 120 4.422 0.510 -10.157 1.00 0.00 O +ATOM 1166 N GLN 121 3.523 -0.617 -11.916 1.00 0.00 N +ATOM 1167 H GLN 121 2.871 -0.615 -12.651 1.00 0.00 H +ATOM 1168 CA GLN 121 4.323 -1.844 -11.756 1.00 0.00 C +ATOM 1169 CB GLN 121 3.754 -3.002 -12.578 1.00 0.00 C +ATOM 1170 CG GLN 121 2.584 -3.727 -11.927 1.00 0.00 C +ATOM 1171 CD GLN 121 2.309 -5.085 -12.556 1.00 0.00 C +ATOM 1172 OE1 GLN 121 2.575 -6.123 -11.950 1.00 0.00 O +ATOM 1173 NE2 GLN 121 1.774 -5.085 -13.775 1.00 0.00 N +ATOM 1174 HE21 GLN 121 1.592 -5.953 -14.191 1.00 0.00 H +ATOM 1175 HE22 GLN 121 1.582 -4.229 -14.213 1.00 0.00 H +ATOM 1176 C GLN 121 5.795 -1.580 -12.121 1.00 0.00 C +ATOM 1177 O GLN 121 6.696 -2.148 -11.496 1.00 0.00 O +ATOM 1178 N ASP 122 6.014 -0.723 -13.135 1.00 0.00 N +ATOM 1179 H ASP 122 5.251 -0.329 -13.615 1.00 0.00 H +ATOM 1180 CA ASP 122 7.358 -0.315 -13.608 1.00 0.00 C +ATOM 1181 CB ASP 122 7.283 0.397 -14.967 1.00 0.00 C +ATOM 1182 CG ASP 122 7.502 -0.549 -16.145 1.00 0.00 C +ATOM 1183 OD1 ASP 122 8.664 -0.693 -16.586 1.00 0.00 O +ATOM 1184 OD2 ASP 122 6.518 -1.137 -16.644 1.00 0.00 O +ATOM 1185 C ASP 122 8.126 0.558 -12.601 1.00 0.00 C +ATOM 1186 O ASP 122 9.340 0.382 -12.444 1.00 0.00 O +ATOM 1187 N ILE 123 7.420 1.485 -11.928 1.00 0.00 N +ATOM 1188 H ILE 123 6.459 1.598 -12.125 1.00 0.00 H +ATOM 1189 CA ILE 123 8.017 2.376 -10.905 1.00 0.00 C +ATOM 1190 CB ILE 123 7.064 3.621 -10.549 1.00 0.00 C +ATOM 1191 CG2 ILE 123 5.799 3.182 -9.783 1.00 0.00 C +ATOM 1192 CG1 ILE 123 7.837 4.717 -9.789 1.00 0.00 C +ATOM 1193 CD1 ILE 123 7.590 6.143 -10.291 1.00 0.00 C +ATOM 1194 C ILE 123 8.414 1.496 -9.686 1.00 0.00 C +ATOM 1195 O ILE 123 9.471 1.707 -9.077 1.00 0.00 O +ATOM 1196 N ALA 124 7.570 0.493 -9.395 1.00 0.00 N +ATOM 1197 H ALA 124 6.735 0.382 -9.911 1.00 0.00 H +ATOM 1198 CA ALA 124 7.774 -0.485 -8.307 1.00 0.00 C +ATOM 1199 CB ALA 124 6.499 -1.312 -8.082 1.00 0.00 C +ATOM 1200 C ALA 124 8.961 -1.411 -8.630 1.00 0.00 C +ATOM 1201 O ALA 124 9.854 -1.583 -7.800 1.00 0.00 O +ATOM 1202 N SER 125 9.004 -1.908 -9.876 1.00 0.00 N +ATOM 1203 H SER 125 8.304 -1.649 -10.512 1.00 0.00 H +ATOM 1204 CA SER 125 10.054 -2.816 -10.388 1.00 0.00 C +ATOM 1205 CB SER 125 9.691 -3.294 -11.801 1.00 0.00 C +ATOM 1206 OG SER 125 10.584 -4.289 -12.271 1.00 0.00 O +ATOM 1207 HG SER 125 10.536 -5.072 -11.716 1.00 0.00 H +ATOM 1208 C SER 125 11.439 -2.144 -10.396 1.00 0.00 C +ATOM 1209 O SER 125 12.444 -2.793 -10.078 1.00 0.00 O +ATOM 1210 N GLU 126 11.469 -0.849 -10.746 1.00 0.00 N +ATOM 1211 H GLU 126 10.634 -0.390 -10.989 1.00 0.00 H +ATOM 1212 CA GLU 126 12.697 -0.033 -10.792 1.00 0.00 C +ATOM 1213 CB GLU 126 12.473 1.263 -11.579 1.00 0.00 C +ATOM 1214 CG GLU 126 12.428 1.049 -13.093 1.00 0.00 C +ATOM 1215 CD GLU 126 12.280 2.338 -13.875 1.00 0.00 C +ATOM 1216 OE1 GLU 126 13.313 2.951 -14.215 1.00 0.00 O +ATOM 1217 OE2 GLU 126 11.129 2.737 -14.153 1.00 0.00 O +ATOM 1218 C GLU 126 13.290 0.249 -9.401 1.00 0.00 C +ATOM 1219 O GLU 126 14.516 0.230 -9.248 1.00 0.00 O +ATOM 1220 N ILE 127 12.425 0.514 -8.407 1.00 0.00 N +ATOM 1221 H ILE 127 11.457 0.570 -8.601 1.00 0.00 H +ATOM 1222 CA ILE 127 12.846 0.758 -7.009 1.00 0.00 C +ATOM 1223 CB ILE 127 11.726 1.517 -6.141 1.00 0.00 C +ATOM 1224 CG2 ILE 127 10.505 0.612 -5.835 1.00 0.00 C +ATOM 1225 CG1 ILE 127 12.344 2.311 -4.949 1.00 0.00 C +ATOM 1226 CD1 ILE 127 12.731 1.548 -3.621 1.00 0.00 C +ATOM 1227 C ILE 127 13.375 -0.560 -6.374 1.00 0.00 C +ATOM 1228 O ILE 127 14.312 -0.524 -5.569 1.00 0.00 O +ATOM 1229 N TYR 128 12.753 -1.692 -6.748 1.00 0.00 N +ATOM 1230 H TYR 128 11.986 -1.639 -7.363 1.00 0.00 H +ATOM 1231 CA TYR 128 13.130 -3.051 -6.291 1.00 0.00 C +ATOM 1232 CB TYR 128 12.153 -4.114 -6.856 1.00 0.00 C +ATOM 1233 CG TYR 128 10.926 -4.504 -6.025 1.00 0.00 C +ATOM 1234 CD1 TYR 128 9.750 -3.716 -6.028 1.00 0.00 C +ATOM 1235 CE1 TYR 128 8.576 -4.131 -5.351 1.00 0.00 C +ATOM 1236 CD2 TYR 128 10.896 -5.724 -5.310 1.00 0.00 C +ATOM 1237 CE2 TYR 128 9.723 -6.148 -4.628 1.00 0.00 C +ATOM 1238 CZ TYR 128 8.571 -5.346 -4.657 1.00 0.00 C +ATOM 1239 OH TYR 128 7.428 -5.759 -4.012 1.00 0.00 O +ATOM 1240 HH TYR 128 6.729 -5.109 -4.119 1.00 0.00 H +ATOM 1241 C TYR 128 14.551 -3.370 -6.799 1.00 0.00 C +ATOM 1242 O TYR 128 15.379 -3.896 -6.047 1.00 0.00 O +ATOM 1243 N ALA 129 14.803 -3.036 -8.076 1.00 0.00 N +ATOM 1244 H ALA 129 14.087 -2.637 -8.622 1.00 0.00 H +ATOM 1245 CA ALA 129 16.092 -3.224 -8.774 1.00 0.00 C +ATOM 1246 CB ALA 129 15.905 -3.039 -10.275 1.00 0.00 C +ATOM 1247 C ALA 129 17.201 -2.290 -8.258 1.00 0.00 C +ATOM 1248 O ALA 129 18.366 -2.695 -8.175 1.00 0.00 O +ATOM 1249 N ASN 130 16.815 -1.050 -7.919 1.00 0.00 N +ATOM 1250 H ASN 130 15.870 -0.792 -8.005 1.00 0.00 H +ATOM 1251 CA ASN 130 17.716 0.001 -7.401 1.00 0.00 C +ATOM 1252 CB ASN 130 17.166 1.394 -7.786 1.00 0.00 C +ATOM 1253 CG ASN 130 18.257 2.462 -7.891 1.00 0.00 C +ATOM 1254 OD1 ASN 130 18.829 2.680 -8.960 1.00 0.00 O +ATOM 1255 ND2 ASN 130 18.534 3.139 -6.780 1.00 0.00 N +ATOM 1256 HD21 ASN 130 19.230 3.827 -6.829 1.00 0.00 H +ATOM 1257 HD22 ASN 130 18.041 2.933 -5.958 1.00 0.00 H +ATOM 1258 C ASN 130 17.856 -0.135 -5.868 1.00 0.00 C +ATOM 1259 O ASN 130 17.088 -0.876 -5.243 1.00 0.00 O +ATOM 1260 N GLY 131 18.828 0.580 -5.286 1.00 0.00 N +ATOM 1261 H GLY 131 19.411 1.163 -5.820 1.00 0.00 H +ATOM 1262 CA GLY 131 19.081 0.541 -3.847 1.00 0.00 C +ATOM 1263 C GLY 131 18.104 1.324 -2.984 1.00 0.00 C +ATOM 1264 O GLY 131 18.303 2.518 -2.736 1.00 0.00 O +ATOM 1265 N GLY 132 17.054 0.633 -2.538 1.00 0.00 N +ATOM 1266 H GLY 132 16.957 -0.314 -2.774 1.00 0.00 H +ATOM 1267 CA GLY 132 16.026 1.232 -1.702 1.00 0.00 C +ATOM 1268 C GLY 132 15.149 0.175 -1.053 1.00 0.00 C +ATOM 1269 O GLY 132 15.210 -0.999 -1.441 1.00 0.00 O +ATOM 1270 N VAL 133 14.339 0.596 -0.072 1.00 0.00 N +ATOM 1271 H VAL 133 14.351 1.544 0.173 1.00 0.00 H +ATOM 1272 CA VAL 133 13.422 -0.282 0.674 1.00 0.00 C +ATOM 1273 CB VAL 133 13.522 -0.006 2.242 1.00 0.00 C +ATOM 1274 CG1 VAL 133 12.726 1.229 2.686 1.00 0.00 C +ATOM 1275 CG2 VAL 133 13.130 -1.244 3.053 1.00 0.00 C +ATOM 1276 C VAL 133 11.976 -0.164 0.126 1.00 0.00 C +ATOM 1277 O VAL 133 11.551 0.933 -0.261 1.00 0.00 O +ATOM 1278 N VAL 134 11.256 -1.295 0.084 1.00 0.00 N +ATOM 1279 H VAL 134 11.645 -2.145 0.385 1.00 0.00 H +ATOM 1280 CA VAL 134 9.862 -1.352 -0.404 1.00 0.00 C +ATOM 1281 CB VAL 134 9.658 -2.461 -1.523 1.00 0.00 C +ATOM 1282 CG1 VAL 134 8.357 -2.221 -2.310 1.00 0.00 C +ATOM 1283 CG2 VAL 134 10.844 -2.488 -2.489 1.00 0.00 C +ATOM 1284 C VAL 134 8.921 -1.618 0.794 1.00 0.00 C +ATOM 1285 O VAL 134 9.135 -2.561 1.570 1.00 0.00 O +ATOM 1286 N ALA 135 7.924 -0.738 0.953 1.00 0.00 N +ATOM 1287 H ALA 135 7.832 0.026 0.342 1.00 0.00 H +ATOM 1288 CA ALA 135 6.909 -0.821 2.014 1.00 0.00 C +ATOM 1289 CB ALA 135 7.130 0.276 3.061 1.00 0.00 C +ATOM 1290 C ALA 135 5.518 -0.690 1.383 1.00 0.00 C +ATOM 1291 O ALA 135 5.278 0.241 0.606 1.00 0.00 O +ATOM 1292 N ALA 136 4.633 -1.647 1.687 1.00 0.00 N +ATOM 1293 H ALA 136 4.884 -2.387 2.282 1.00 0.00 H +ATOM 1294 CA ALA 136 3.252 -1.681 1.176 1.00 0.00 C +ATOM 1295 CB ALA 136 3.080 -2.810 0.182 1.00 0.00 C +ATOM 1296 C ALA 136 2.266 -1.843 2.333 1.00 0.00 C +ATOM 1297 O ALA 136 2.553 -2.577 3.281 1.00 0.00 O +ATOM 1298 N VAL 137 1.106 -1.179 2.234 1.00 0.00 N +ATOM 1299 H VAL 137 0.910 -0.632 1.442 1.00 0.00 H +ATOM 1300 CA VAL 137 0.053 -1.211 3.272 1.00 0.00 C +ATOM 1301 CB VAL 137 -0.385 0.249 3.710 1.00 0.00 C +ATOM 1302 CG1 VAL 137 -0.946 0.247 5.131 1.00 0.00 C +ATOM 1303 CG2 VAL 137 0.792 1.224 3.632 1.00 0.00 C +ATOM 1304 C VAL 137 -1.170 -2.025 2.780 1.00 0.00 C +ATOM 1305 O VAL 137 -1.562 -1.918 1.612 1.00 0.00 O +ATOM 1306 N CYS 138 -1.733 -2.841 3.691 1.00 0.00 N +ATOM 1307 H CYS 138 -1.362 -2.845 4.589 1.00 0.00 H +ATOM 1308 CA CYS 138 -2.907 -3.741 3.506 1.00 0.00 C +ATOM 1309 CB CYS 138 -4.212 -3.024 3.885 1.00 0.00 C +ATOM 1310 SG CYS 138 -4.501 -1.464 3.025 1.00 0.00 S +ATOM 1311 C CYS 138 -3.042 -4.535 2.186 1.00 0.00 C +ATOM 1312 O CYS 138 -2.702 -5.723 2.144 1.00 0.00 O +ATOM 1313 N HIS 139 -3.626 -3.897 1.166 1.00 0.00 N +ATOM 1314 H HIS 139 -3.967 -2.987 1.317 1.00 0.00 H +ATOM 1315 CA HIS 139 -3.818 -4.413 -0.197 1.00 0.00 C +ATOM 1316 CB HIS 139 -4.927 -3.644 -0.922 1.00 0.00 C +ATOM 1317 CG HIS 139 -6.315 -4.070 -0.534 1.00 0.00 C +ATOM 1318 CD2 HIS 139 -7.285 -4.700 -1.242 1.00 0.00 C +ATOM 1319 ND1 HIS 139 -6.835 -3.868 0.727 1.00 0.00 N +ATOM 1320 HD1 HIS 139 -6.373 -3.431 1.472 1.00 0.00 H +ATOM 1321 CE1 HIS 139 -8.062 -4.356 0.781 1.00 0.00 C +ATOM 1322 NE2 HIS 139 -8.358 -4.865 -0.400 1.00 0.00 N +ATOM 1323 HE2 HIS 139 -9.207 -5.293 -0.639 1.00 0.00 H +ATOM 1324 C HIS 139 -2.501 -4.480 -0.980 1.00 0.00 C +ATOM 1325 O HIS 139 -2.371 -5.243 -1.949 1.00 0.00 O +ATOM 1326 N GLY 140 -1.553 -3.627 -0.560 1.00 0.00 N +ATOM 1327 H GLY 140 -1.725 -3.022 0.186 1.00 0.00 H +ATOM 1328 CA GLY 140 -0.229 -3.525 -1.170 1.00 0.00 C +ATOM 1329 C GLY 140 0.500 -4.871 -1.280 1.00 0.00 C +ATOM 1330 O GLY 140 1.108 -5.094 -2.336 1.00 0.00 O +ATOM 1331 N PRO 141 0.494 -5.771 -0.244 1.00 0.00 N +ATOM 1332 CD PRO 141 0.217 -5.476 1.181 1.00 0.00 C +ATOM 1333 CA PRO 141 1.161 -7.084 -0.333 1.00 0.00 C +ATOM 1334 CB PRO 141 0.831 -7.720 1.012 1.00 0.00 C +ATOM 1335 CG PRO 141 0.954 -6.576 1.914 1.00 0.00 C +ATOM 1336 C PRO 141 0.570 -7.902 -1.496 1.00 0.00 C +ATOM 1337 O PRO 141 1.293 -8.642 -2.169 1.00 0.00 O +ATOM 1338 N ALA 142 -0.745 -7.736 -1.712 1.00 0.00 N +ATOM 1339 H ALA 142 -1.269 -7.140 -1.132 1.00 0.00 H +ATOM 1340 CA ALA 142 -1.509 -8.396 -2.788 1.00 0.00 C +ATOM 1341 CB ALA 142 -3.024 -8.236 -2.544 1.00 0.00 C +ATOM 1342 C ALA 142 -1.128 -7.876 -4.187 1.00 0.00 C +ATOM 1343 O ALA 142 -0.930 -8.676 -5.110 1.00 0.00 O +ATOM 1344 N ILE 143 -1.031 -6.544 -4.322 1.00 0.00 N +ATOM 1345 H ILE 143 -1.191 -5.966 -3.542 1.00 0.00 H +ATOM 1346 CA ILE 143 -0.684 -5.860 -5.590 1.00 0.00 C +ATOM 1347 CB ILE 143 -1.243 -4.385 -5.659 1.00 0.00 C +ATOM 1348 CG2 ILE 143 -2.779 -4.449 -5.579 1.00 0.00 C +ATOM 1349 CG1 ILE 143 -0.641 -3.497 -4.548 1.00 0.00 C +ATOM 1350 CD1 ILE 143 -0.859 -1.978 -4.658 1.00 0.00 C +ATOM 1351 C ILE 143 0.750 -5.932 -6.162 1.00 0.00 C +ATOM 1352 O ILE 143 0.903 -6.151 -7.371 1.00 0.00 O +ATOM 1353 N PHE 144 1.780 -5.780 -5.311 1.00 0.00 N +ATOM 1354 H PHE 144 1.621 -5.654 -4.350 1.00 0.00 H +ATOM 1355 CA PHE 144 3.182 -5.794 -5.784 1.00 0.00 C +ATOM 1356 CB PHE 144 4.189 -5.169 -4.762 1.00 0.00 C +ATOM 1357 CG PHE 144 4.352 -5.908 -3.421 1.00 0.00 C +ATOM 1358 CD1 PHE 144 4.755 -7.268 -3.344 1.00 0.00 C +ATOM 1359 CD2 PHE 144 4.223 -5.190 -2.220 1.00 0.00 C +ATOM 1360 CE1 PHE 144 5.027 -7.888 -2.097 1.00 0.00 C +ATOM 1361 CE2 PHE 144 4.495 -5.799 -0.963 1.00 0.00 C +ATOM 1362 CZ PHE 144 4.898 -7.150 -0.904 1.00 0.00 C +ATOM 1363 C PHE 144 3.752 -7.072 -6.436 1.00 0.00 C +ATOM 1364 O PHE 144 4.517 -6.967 -7.399 1.00 0.00 O +ATOM 1365 N ASP 145 3.364 -8.252 -5.931 1.00 0.00 N +ATOM 1366 H ASP 145 2.734 -8.279 -5.178 1.00 0.00 H +ATOM 1367 CA ASP 145 3.835 -9.556 -6.450 1.00 0.00 C +ATOM 1368 CB ASP 145 3.746 -10.665 -5.362 1.00 0.00 C +ATOM 1369 CG ASP 145 2.444 -10.627 -4.546 1.00 0.00 C +ATOM 1370 OD1 ASP 145 2.543 -10.556 -3.304 1.00 0.00 O +ATOM 1371 OD2 ASP 145 1.337 -10.696 -5.128 1.00 0.00 O +ATOM 1372 C ASP 145 3.197 -10.010 -7.787 1.00 0.00 C +ATOM 1373 O ASP 145 2.014 -10.376 -7.833 1.00 0.00 O +ATOM 1374 N GLY 146 3.988 -9.926 -8.864 1.00 0.00 N +ATOM 1375 H GLY 146 4.911 -9.596 -8.793 1.00 0.00 H +ATOM 1376 CA GLY 146 3.539 -10.313 -10.197 1.00 0.00 C +ATOM 1377 C GLY 146 4.374 -9.714 -11.321 1.00 0.00 C +ATOM 1378 O GLY 146 3.925 -9.688 -12.474 1.00 0.00 O +ATOM 1379 N LEU 147 5.579 -9.240 -10.979 1.00 0.00 N +ATOM 1380 H LEU 147 5.846 -9.302 -10.041 1.00 0.00 H +ATOM 1381 CA LEU 147 6.531 -8.619 -11.919 1.00 0.00 C +ATOM 1382 CB LEU 147 6.949 -7.228 -11.405 1.00 0.00 C +ATOM 1383 CG LEU 147 6.089 -5.992 -11.707 1.00 0.00 C +ATOM 1384 CD1 LEU 147 5.986 -5.125 -10.460 1.00 0.00 C +ATOM 1385 CD2 LEU 147 6.674 -5.183 -12.879 1.00 0.00 C +ATOM 1386 C LEU 147 7.785 -9.476 -12.169 1.00 0.00 C +ATOM 1387 O LEU 147 8.066 -10.395 -11.397 1.00 0.00 O +ATOM 1388 N THR 148 8.540 -9.140 -13.228 1.00 0.00 N +ATOM 1389 H THR 148 8.285 -8.375 -13.789 1.00 0.00 H +ATOM 1390 CA THR 148 9.773 -9.847 -13.640 1.00 0.00 C +ATOM 1391 CB THR 148 9.821 -10.054 -15.211 1.00 0.00 C +ATOM 1392 OG1 THR 148 11.100 -10.572 -15.603 1.00 0.00 O +ATOM 1393 HG1 THR 148 11.794 -9.946 -15.382 1.00 0.00 H +ATOM 1394 CG2 THR 148 9.526 -8.749 -15.986 1.00 0.00 C +ATOM 1395 C THR 148 11.102 -9.239 -13.124 1.00 0.00 C +ATOM 1396 O THR 148 12.029 -9.986 -12.781 1.00 0.00 O +ATOM 1397 N ASP 149 11.172 -7.895 -13.085 1.00 0.00 N +ATOM 1398 H ASP 149 10.391 -7.371 -13.368 1.00 0.00 H +ATOM 1399 CA ASP 149 12.333 -7.064 -12.650 1.00 0.00 C +ATOM 1400 CB ASP 149 12.826 -7.428 -11.223 1.00 0.00 C +ATOM 1401 CG ASP 149 13.344 -6.219 -10.440 1.00 0.00 C +ATOM 1402 OD1 ASP 149 12.538 -5.568 -9.740 1.00 0.00 O +ATOM 1403 OD2 ASP 149 14.559 -5.932 -10.515 1.00 0.00 O +ATOM 1404 C ASP 149 13.516 -7.040 -13.646 1.00 0.00 C +ATOM 1405 O ASP 149 14.150 -5.992 -13.818 1.00 0.00 O +ATOM 1406 N LYS 150 13.793 -8.186 -14.287 1.00 0.00 N +ATOM 1407 H LYS 150 13.270 -8.997 -14.119 1.00 0.00 H +ATOM 1408 CA LYS 150 14.885 -8.331 -15.271 1.00 0.00 C +ATOM 1409 CB LYS 150 15.728 -9.586 -14.973 1.00 0.00 C +ATOM 1410 CG LYS 150 16.557 -9.511 -13.695 1.00 0.00 C +ATOM 1411 CD LYS 150 17.358 -10.790 -13.478 1.00 0.00 C +ATOM 1412 CE LYS 150 18.196 -10.737 -12.202 1.00 0.00 C +ATOM 1413 NZ LYS 150 17.381 -10.753 -10.951 1.00 0.00 N +ATOM 1414 HZ1 LYS 150 18.012 -10.715 -10.125 1.00 0.00 H +ATOM 1415 HZ2 LYS 150 16.817 -11.626 -10.916 1.00 0.00 H +ATOM 1416 HZ3 LYS 150 16.746 -9.930 -10.940 1.00 0.00 H +ATOM 1417 C LYS 150 14.372 -8.329 -16.729 1.00 0.00 C +ATOM 1418 O LYS 150 14.315 -7.261 -17.350 1.00 0.00 O +ATOM 1419 N LYS 151 14.008 -9.508 -17.260 1.00 0.00 N +ATOM 1420 H LYS 151 14.067 -10.333 -16.732 1.00 0.00 H +ATOM 1421 CA LYS 151 13.492 -9.674 -18.634 1.00 0.00 C +ATOM 1422 CB LYS 151 14.508 -10.412 -19.533 1.00 0.00 C +ATOM 1423 CG LYS 151 15.769 -9.619 -19.860 1.00 0.00 C +ATOM 1424 CD LYS 151 16.710 -10.419 -20.746 1.00 0.00 C +ATOM 1425 CE LYS 151 17.966 -9.629 -21.073 1.00 0.00 C +ATOM 1426 NZ LYS 151 18.898 -10.401 -21.941 1.00 0.00 N +ATOM 1427 HZ1 LYS 151 19.181 -11.275 -21.454 1.00 0.00 H +ATOM 1428 HZ2 LYS 151 18.422 -10.639 -22.834 1.00 0.00 H +ATOM 1429 HZ3 LYS 151 19.742 -9.826 -22.140 1.00 0.00 H +ATOM 1430 C LYS 151 12.144 -10.418 -18.615 1.00 0.00 C +ATOM 1431 O LYS 151 11.096 -9.791 -18.814 1.00 0.00 O +ATOM 1432 N THR 152 12.182 -11.740 -18.377 1.00 0.00 N +ATOM 1433 H THR 152 13.045 -12.187 -18.234 1.00 0.00 H +ATOM 1434 CA THR 152 10.993 -12.613 -18.311 1.00 0.00 C +ATOM 1435 CB THR 152 10.980 -13.674 -19.472 1.00 0.00 C +ATOM 1436 OG1 THR 152 11.667 -13.143 -20.612 1.00 0.00 O +ATOM 1437 HG1 THR 152 11.210 -12.368 -20.951 1.00 0.00 H +ATOM 1438 CG2 THR 152 9.541 -14.012 -19.894 1.00 0.00 C +ATOM 1439 C THR 152 11.010 -13.324 -16.943 1.00 0.00 C +ATOM 1440 O THR 152 12.065 -13.799 -16.497 1.00 0.00 O +ATOM 1441 N GLY 153 9.854 -13.338 -16.274 1.00 0.00 N +ATOM 1442 H GLY 153 9.045 -12.919 -16.640 1.00 0.00 H +ATOM 1443 CA GLY 153 9.732 -13.976 -14.970 1.00 0.00 C +ATOM 1444 C GLY 153 8.560 -13.467 -14.148 1.00 0.00 C +ATOM 1445 O GLY 153 7.803 -12.605 -14.607 1.00 0.00 O +ATOM 1446 N ARG 154 8.403 -14.038 -12.947 1.00 0.00 N +ATOM 1447 H ARG 154 9.017 -14.763 -12.724 1.00 0.00 H +ATOM 1448 CA ARG 154 7.335 -13.694 -11.989 1.00 0.00 C +ATOM 1449 CB ARG 154 6.327 -14.854 -11.854 1.00 0.00 C +ATOM 1450 CG ARG 154 5.462 -15.096 -13.088 1.00 0.00 C +ATOM 1451 CD ARG 154 4.523 -16.274 -12.886 1.00 0.00 C +ATOM 1452 NE ARG 154 3.685 -16.519 -14.063 1.00 0.00 N +ATOM 1453 HE ARG 154 3.797 -15.932 -14.840 1.00 0.00 H +ATOM 1454 CZ ARG 154 2.772 -17.486 -14.168 1.00 0.00 C +ATOM 1455 NH1 ARG 154 2.075 -17.607 -15.289 1.00 0.00 N +ATOM 1456 HH11 ARG 154 2.235 -16.975 -16.048 1.00 0.00 H +ATOM 1457 HH12 ARG 154 1.388 -18.329 -15.375 1.00 0.00 H +ATOM 1458 NH2 ARG 154 2.548 -18.333 -13.168 1.00 0.00 N +ATOM 1459 HH21 ARG 154 3.068 -18.252 -12.317 1.00 0.00 H +ATOM 1460 HH22 ARG 154 1.859 -19.051 -13.266 1.00 0.00 H +ATOM 1461 C ARG 154 7.819 -13.261 -10.572 1.00 0.00 C +ATOM 1462 O ARG 154 7.135 -12.445 -9.940 1.00 0.00 O +ATOM 1463 N PRO 155 8.985 -13.780 -10.053 1.00 0.00 N +ATOM 1464 CD PRO 155 9.812 -14.928 -10.493 1.00 0.00 C +ATOM 1465 CA PRO 155 9.437 -13.366 -8.702 1.00 0.00 C +ATOM 1466 CB PRO 155 10.407 -14.483 -8.301 1.00 0.00 C +ATOM 1467 CG PRO 155 10.081 -15.626 -9.204 1.00 0.00 C +ATOM 1468 C PRO 155 10.135 -11.996 -8.521 1.00 0.00 C +ATOM 1469 O PRO 155 10.705 -11.448 -9.473 1.00 0.00 O +ATOM 1470 N LEU 156 10.064 -11.477 -7.284 1.00 0.00 N +ATOM 1471 H LEU 156 9.557 -11.955 -6.590 1.00 0.00 H +ATOM 1472 CA LEU 156 10.681 -10.210 -6.825 1.00 0.00 C +ATOM 1473 CB LEU 156 9.712 -8.993 -6.940 1.00 0.00 C +ATOM 1474 CG LEU 156 8.879 -8.468 -8.135 1.00 0.00 C +ATOM 1475 CD1 LEU 156 9.730 -8.234 -9.392 1.00 0.00 C +ATOM 1476 CD2 LEU 156 7.679 -9.376 -8.424 1.00 0.00 C +ATOM 1477 C LEU 156 10.981 -10.424 -5.340 1.00 0.00 C +ATOM 1478 O LEU 156 12.044 -10.031 -4.844 1.00 0.00 O +ATOM 1479 N ILE 157 10.015 -11.057 -4.657 1.00 0.00 N +ATOM 1480 H ILE 157 9.201 -11.361 -5.118 1.00 0.00 H +ATOM 1481 CA ILE 157 10.038 -11.367 -3.217 1.00 0.00 C +ATOM 1482 CB ILE 157 8.745 -10.756 -2.483 1.00 0.00 C +ATOM 1483 CG2 ILE 157 9.095 -10.330 -1.062 1.00 0.00 C +ATOM 1484 CG1 ILE 157 8.202 -9.500 -3.197 1.00 0.00 C +ATOM 1485 CD1 ILE 157 7.158 -9.756 -4.303 1.00 0.00 C +ATOM 1486 C ILE 157 10.098 -12.916 -3.084 1.00 0.00 C +ATOM 1487 O ILE 157 9.238 -13.541 -2.443 1.00 0.00 O +ATOM 1488 N GLU 158 11.135 -13.510 -3.694 1.00 0.00 N +ATOM 1489 H GLU 158 11.800 -12.970 -4.175 1.00 0.00 H +ATOM 1490 CA GLU 158 11.375 -14.970 -3.708 1.00 0.00 C +ATOM 1491 CB GLU 158 12.156 -15.390 -4.982 1.00 0.00 C +ATOM 1492 CG GLU 158 13.429 -14.574 -5.364 1.00 0.00 C +ATOM 1493 CD GLU 158 14.726 -15.191 -4.851 1.00 0.00 C +ATOM 1494 OE1 GLU 158 15.339 -15.989 -5.591 1.00 0.00 O +ATOM 1495 OE2 GLU 158 15.127 -14.876 -3.711 1.00 0.00 O +ATOM 1496 C GLU 158 12.031 -15.556 -2.442 1.00 0.00 C +ATOM 1497 O GLU 158 11.640 -16.635 -1.983 1.00 0.00 O +ATOM 1498 N GLY 159 13.018 -14.834 -1.900 1.00 0.00 N +ATOM 1499 H GLY 159 13.304 -13.984 -2.299 1.00 0.00 H +ATOM 1500 CA GLY 159 13.725 -15.259 -0.695 1.00 0.00 C +ATOM 1501 C GLY 159 13.330 -14.432 0.517 1.00 0.00 C +ATOM 1502 O GLY 159 13.774 -14.711 1.637 1.00 0.00 O +ATOM 1503 N LYS 160 12.494 -13.416 0.271 1.00 0.00 N +ATOM 1504 H LYS 160 12.196 -13.261 -0.651 1.00 0.00 H +ATOM 1505 CA LYS 160 11.975 -12.494 1.293 1.00 0.00 C +ATOM 1506 CB LYS 160 12.184 -11.034 0.865 1.00 0.00 C +ATOM 1507 CG LYS 160 13.645 -10.636 0.656 1.00 0.00 C +ATOM 1508 CD LYS 160 13.766 -9.259 0.017 1.00 0.00 C +ATOM 1509 CE LYS 160 15.213 -8.913 -0.332 1.00 0.00 C +ATOM 1510 NZ LYS 160 15.774 -9.739 -1.443 1.00 0.00 N +ATOM 1511 HZ1 LYS 160 15.205 -9.596 -2.302 1.00 0.00 H +ATOM 1512 HZ2 LYS 160 16.756 -9.451 -1.627 1.00 0.00 H +ATOM 1513 HZ3 LYS 160 15.751 -10.743 -1.175 1.00 0.00 H +ATOM 1514 C LYS 160 10.480 -12.787 1.492 1.00 0.00 C +ATOM 1515 O LYS 160 9.730 -12.863 0.512 1.00 0.00 O +ATOM 1516 N SER 161 10.064 -12.958 2.753 1.00 0.00 N +ATOM 1517 H SER 161 10.695 -12.871 3.499 1.00 0.00 H +ATOM 1518 CA SER 161 8.672 -13.278 3.119 1.00 0.00 C +ATOM 1519 CB SER 161 8.664 -14.170 4.364 1.00 0.00 C +ATOM 1520 OG SER 161 9.407 -13.588 5.423 1.00 0.00 O +ATOM 1521 HG SER 161 9.028 -12.745 5.687 1.00 0.00 H +ATOM 1522 C SER 161 7.723 -12.080 3.315 1.00 0.00 C +ATOM 1523 O SER 161 8.033 -11.148 4.068 1.00 0.00 O +ATOM 1524 N ILE 162 6.587 -12.114 2.600 1.00 0.00 N +ATOM 1525 H ILE 162 6.405 -12.864 1.992 1.00 0.00 H +ATOM 1526 CA ILE 162 5.537 -11.074 2.649 1.00 0.00 C +ATOM 1527 CB ILE 162 5.555 -10.126 1.365 1.00 0.00 C +ATOM 1528 CG2 ILE 162 6.718 -9.150 1.461 1.00 0.00 C +ATOM 1529 CG1 ILE 162 5.621 -10.913 0.034 1.00 0.00 C +ATOM 1530 CD1 ILE 162 4.271 -11.112 -0.684 1.00 0.00 C +ATOM 1531 C ILE 162 4.125 -11.663 2.894 1.00 0.00 C +ATOM 1532 O ILE 162 3.713 -12.596 2.193 1.00 0.00 O +ATOM 1533 N THR 163 3.429 -11.147 3.920 1.00 0.00 N +ATOM 1534 H THR 163 3.821 -10.435 4.472 1.00 0.00 H +ATOM 1535 CA THR 163 2.065 -11.577 4.307 1.00 0.00 C +ATOM 1536 CB THR 163 2.085 -12.349 5.679 1.00 0.00 C +ATOM 1537 OG1 THR 163 3.275 -13.140 5.766 1.00 0.00 O +ATOM 1538 HG1 THR 163 4.074 -12.643 5.607 1.00 0.00 H +ATOM 1539 CG2 THR 163 0.859 -13.264 5.830 1.00 0.00 C +ATOM 1540 C THR 163 1.155 -10.341 4.457 1.00 0.00 C +ATOM 1541 O THR 163 1.539 -9.377 5.134 1.00 0.00 O +ATOM 1542 N GLY 164 0.001 -10.328 3.779 1.00 0.00 N +ATOM 1543 H GLY 164 -0.254 -11.058 3.174 1.00 0.00 H +ATOM 1544 CA GLY 164 -0.898 -9.195 3.945 1.00 0.00 C +ATOM 1545 C GLY 164 -2.389 -9.378 4.178 1.00 0.00 C +ATOM 1546 O GLY 164 -3.085 -9.935 3.323 1.00 0.00 O +ATOM 1547 N PHE 165 -2.857 -8.919 5.351 1.00 0.00 N +ATOM 1548 H PHE 165 -2.219 -8.550 5.998 1.00 0.00 H +ATOM 1549 CA PHE 165 -4.277 -8.925 5.754 1.00 0.00 C +ATOM 1550 CB PHE 165 -4.670 -10.197 6.567 1.00 0.00 C +ATOM 1551 CG PHE 165 -6.186 -10.495 6.601 1.00 0.00 C +ATOM 1552 CD1 PHE 165 -6.808 -11.198 5.551 1.00 0.00 C +ATOM 1553 CD2 PHE 165 -6.994 -10.065 7.681 1.00 0.00 C +ATOM 1554 CE1 PHE 165 -8.201 -11.467 5.561 1.00 0.00 C +ATOM 1555 CE2 PHE 165 -8.389 -10.325 7.708 1.00 0.00 C +ATOM 1556 CZ PHE 165 -8.994 -11.028 6.642 1.00 0.00 C +ATOM 1557 C PHE 165 -4.719 -7.633 6.478 1.00 0.00 C +ATOM 1558 O PHE 165 -4.678 -6.540 5.902 1.00 0.00 O +ATOM 1559 N THR 166 -5.111 -7.799 7.762 1.00 0.00 N +ATOM 1560 H THR 166 -5.065 -8.664 8.215 1.00 0.00 H +ATOM 1561 CA THR 166 -5.617 -6.794 8.732 1.00 0.00 C +ATOM 1562 CB THR 166 -4.463 -5.878 9.296 1.00 0.00 C +ATOM 1563 OG1 THR 166 -3.356 -6.705 9.665 1.00 0.00 O +ATOM 1564 HG1 THR 166 -3.008 -7.176 8.904 1.00 0.00 H +ATOM 1565 CG2 THR 166 -4.911 -5.084 10.539 1.00 0.00 C +ATOM 1566 C THR 166 -6.896 -6.034 8.281 1.00 0.00 C +ATOM 1567 O THR 166 -7.665 -5.552 9.126 1.00 0.00 O +ATOM 1568 N ASP 167 -7.128 -5.989 6.961 1.00 0.00 N +ATOM 1569 H ASP 167 -6.537 -6.386 6.305 1.00 0.00 H +ATOM 1570 CA ASP 167 -8.304 -5.350 6.352 1.00 0.00 C +ATOM 1571 CB ASP 167 -7.895 -4.432 5.174 1.00 0.00 C +ATOM 1572 CG ASP 167 -8.911 -3.319 4.899 1.00 0.00 C +ATOM 1573 OD1 ASP 167 -8.772 -2.222 5.484 1.00 0.00 O +ATOM 1574 OD2 ASP 167 -9.837 -3.539 4.088 1.00 0.00 O +ATOM 1575 C ASP 167 -9.221 -6.484 5.859 1.00 0.00 C +ATOM 1576 O ASP 167 -10.245 -6.760 6.496 1.00 0.00 O +ATOM 1577 N VAL 168 -8.819 -7.153 4.760 1.00 0.00 N +ATOM 1578 H VAL 168 -7.969 -6.917 4.328 1.00 0.00 H +ATOM 1579 CA VAL 168 -9.571 -8.254 4.120 1.00 0.00 C +ATOM 1580 CB VAL 168 -10.942 -7.685 3.493 1.00 0.00 C +ATOM 1581 CG1 VAL 168 -10.711 -6.852 2.218 1.00 0.00 C +ATOM 1582 CG2 VAL 168 -11.996 -8.788 3.320 1.00 0.00 C +ATOM 1583 C VAL 168 -8.705 -8.980 3.048 1.00 0.00 C +ATOM 1584 O VAL 168 -9.254 -9.688 2.199 1.00 0.00 O +ATOM 1585 N GLY 169 -7.373 -8.931 3.171 1.00 0.00 N +ATOM 1586 H GLY 169 -6.953 -8.504 3.949 1.00 0.00 H +ATOM 1587 CA GLY 169 -6.508 -9.519 2.144 1.00 0.00 C +ATOM 1588 C GLY 169 -6.569 -10.991 1.742 1.00 0.00 C +ATOM 1589 O GLY 169 -6.841 -11.273 0.568 1.00 0.00 O +ATOM 1590 N GLU 170 -6.450 -11.910 2.705 1.00 0.00 N +ATOM 1591 H GLU 170 -6.251 -11.602 3.597 1.00 0.00 H +ATOM 1592 CA GLU 170 -6.512 -13.363 2.459 1.00 0.00 C +ATOM 1593 CB GLU 170 -5.936 -14.157 3.636 1.00 0.00 C +ATOM 1594 CG GLU 170 -4.417 -14.089 3.743 1.00 0.00 C +ATOM 1595 CD GLU 170 -3.858 -15.066 4.754 1.00 0.00 C +ATOM 1596 OE1 GLU 170 -3.745 -14.693 5.938 1.00 0.00 O +ATOM 1597 OE2 GLU 170 -3.528 -16.206 4.366 1.00 0.00 O +ATOM 1598 C GLU 170 -7.918 -13.866 2.109 1.00 0.00 C +ATOM 1599 O GLU 170 -8.071 -14.733 1.240 1.00 0.00 O +ATOM 1600 N THR 171 -8.925 -13.313 2.800 1.00 0.00 N +ATOM 1601 H THR 171 -8.713 -12.626 3.471 1.00 0.00 H +ATOM 1602 CA THR 171 -10.351 -13.651 2.617 1.00 0.00 C +ATOM 1603 CB THR 171 -11.222 -13.129 3.799 1.00 0.00 C +ATOM 1604 OG1 THR 171 -11.007 -11.723 3.979 1.00 0.00 O +ATOM 1605 HG1 THR 171 -10.086 -11.518 4.136 1.00 0.00 H +ATOM 1606 CG2 THR 171 -10.888 -13.868 5.092 1.00 0.00 C +ATOM 1607 C THR 171 -10.959 -13.176 1.281 1.00 0.00 C +ATOM 1608 O THR 171 -11.639 -13.961 0.606 1.00 0.00 O +ATOM 1609 N ILE 172 -10.704 -11.909 0.908 1.00 0.00 N +ATOM 1610 H ILE 172 -10.137 -11.348 1.481 1.00 0.00 H +ATOM 1611 CA ILE 172 -11.224 -11.313 -0.339 1.00 0.00 C +ATOM 1612 CB ILE 172 -11.235 -9.724 -0.255 1.00 0.00 C +ATOM 1613 CG2 ILE 172 -9.903 -9.085 -0.747 1.00 0.00 C +ATOM 1614 CG1 ILE 172 -12.475 -9.161 -0.976 1.00 0.00 C +ATOM 1615 CD1 ILE 172 -13.161 -7.988 -0.267 1.00 0.00 C +ATOM 1616 C ILE 172 -10.570 -11.859 -1.634 1.00 0.00 C +ATOM 1617 O ILE 172 -11.282 -12.251 -2.562 1.00 0.00 O +ATOM 1618 N LEU 173 -9.230 -11.876 -1.671 1.00 0.00 N +ATOM 1619 H LEU 173 -8.705 -11.549 -0.899 1.00 0.00 H +ATOM 1620 CA LEU 173 -8.450 -12.377 -2.813 1.00 0.00 C +ATOM 1621 CB LEU 173 -7.011 -11.833 -2.773 1.00 0.00 C +ATOM 1622 CG LEU 173 -6.723 -10.368 -3.158 1.00 0.00 C +ATOM 1623 CD1 LEU 173 -6.396 -9.510 -1.930 1.00 0.00 C +ATOM 1624 CD2 LEU 173 -5.559 -10.314 -4.139 1.00 0.00 C +ATOM 1625 C LEU 173 -8.473 -13.906 -2.940 1.00 0.00 C +ATOM 1626 O LEU 173 -8.673 -14.439 -4.038 1.00 0.00 O +ATOM 1627 N GLY 174 -8.265 -14.586 -1.802 1.00 0.00 N +ATOM 1628 H GLY 174 -8.100 -14.111 -0.957 1.00 0.00 H +ATOM 1629 CA GLY 174 -8.264 -16.046 -1.712 1.00 0.00 C +ATOM 1630 C GLY 174 -7.360 -16.799 -2.676 1.00 0.00 C +ATOM 1631 O GLY 174 -6.136 -16.621 -2.658 1.00 0.00 O +ATOM 1632 N VAL 175 -7.987 -17.659 -3.490 1.00 0.00 N +ATOM 1633 H VAL 175 -8.959 -17.762 -3.409 1.00 0.00 H +ATOM 1634 CA VAL 175 -7.327 -18.482 -4.520 1.00 0.00 C +ATOM 1635 CB VAL 175 -7.424 -20.034 -4.209 1.00 0.00 C +ATOM 1636 CG1 VAL 175 -6.433 -20.834 -5.074 1.00 0.00 C +ATOM 1637 CG2 VAL 175 -7.155 -20.323 -2.730 1.00 0.00 C +ATOM 1638 C VAL 175 -8.060 -18.156 -5.843 1.00 0.00 C +ATOM 1639 O VAL 175 -9.212 -17.701 -5.813 1.00 0.00 O +ATOM 1640 N ASP 176 -7.391 -18.393 -6.982 1.00 0.00 N +ATOM 1641 H ASP 176 -6.481 -18.762 -6.931 1.00 0.00 H +ATOM 1642 CA ASP 176 -7.927 -18.141 -8.337 1.00 0.00 C +ATOM 1643 CB ASP 176 -6.796 -18.254 -9.378 1.00 0.00 C +ATOM 1644 CG ASP 176 -7.004 -17.346 -10.594 1.00 0.00 C +ATOM 1645 OD1 ASP 176 -6.532 -16.188 -10.566 1.00 0.00 O +ATOM 1646 OD2 ASP 176 -7.626 -17.798 -11.581 1.00 0.00 O +ATOM 1647 C ASP 176 -9.094 -19.089 -8.703 1.00 0.00 C +ATOM 1648 O ASP 176 -10.048 -18.668 -9.368 1.00 0.00 O +ATOM 1649 N SER 177 -8.992 -20.353 -8.265 1.00 0.00 N +ATOM 1650 H SER 177 -8.204 -20.613 -7.737 1.00 0.00 H +ATOM 1651 CA SER 177 -9.993 -21.413 -8.508 1.00 0.00 C +ATOM 1652 CB SER 177 -9.395 -22.788 -8.186 1.00 0.00 C +ATOM 1653 OG SER 177 -8.261 -23.053 -8.994 1.00 0.00 O +ATOM 1654 HG SER 177 -7.906 -23.917 -8.774 1.00 0.00 H +ATOM 1655 C SER 177 -11.347 -21.251 -7.783 1.00 0.00 C +ATOM 1656 O SER 177 -12.400 -21.455 -8.399 1.00 0.00 O +ATOM 1657 N ILE 178 -11.302 -20.888 -6.491 1.00 0.00 N +ATOM 1658 H ILE 178 -10.423 -20.727 -6.079 1.00 0.00 H +ATOM 1659 CA ILE 178 -12.494 -20.697 -5.632 1.00 0.00 C +ATOM 1660 CB ILE 178 -12.092 -20.750 -4.085 1.00 0.00 C +ATOM 1661 CG2 ILE 178 -11.188 -19.544 -3.694 1.00 0.00 C +ATOM 1662 CG1 ILE 178 -13.336 -20.909 -3.184 1.00 0.00 C +ATOM 1663 CD1 ILE 178 -13.124 -21.756 -1.922 1.00 0.00 C +ATOM 1664 C ILE 178 -13.373 -19.463 -6.003 1.00 0.00 C +ATOM 1665 O ILE 178 -14.602 -19.584 -6.074 1.00 0.00 O +ATOM 1666 N LEU 179 -12.727 -18.310 -6.229 1.00 0.00 N +ATOM 1667 H LEU 179 -11.748 -18.270 -6.157 1.00 0.00 H +ATOM 1668 CA LEU 179 -13.403 -17.049 -6.592 1.00 0.00 C +ATOM 1669 CB LEU 179 -13.098 -15.925 -5.559 1.00 0.00 C +ATOM 1670 CG LEU 179 -11.704 -15.489 -5.059 1.00 0.00 C +ATOM 1671 CD1 LEU 179 -11.560 -13.983 -5.228 1.00 0.00 C +ATOM 1672 CD2 LEU 179 -11.489 -15.889 -3.599 1.00 0.00 C +ATOM 1673 C LEU 179 -13.075 -16.598 -8.031 1.00 0.00 C +ATOM 1674 O LEU 179 -12.057 -17.019 -8.593 1.00 0.00 O +ATOM 1675 N LYS 180 -13.943 -15.749 -8.602 1.00 0.00 N +ATOM 1676 H LYS 180 -14.738 -15.450 -8.109 1.00 0.00 H +ATOM 1677 CA LYS 180 -13.797 -15.204 -9.966 1.00 0.00 C +ATOM 1678 CB LYS 180 -15.163 -15.119 -10.662 1.00 0.00 C +ATOM 1679 CG LYS 180 -15.787 -16.468 -11.007 1.00 0.00 C +ATOM 1680 CD LYS 180 -17.135 -16.297 -11.688 1.00 0.00 C +ATOM 1681 CE LYS 180 -17.755 -17.641 -12.031 1.00 0.00 C +ATOM 1682 NZ LYS 180 -19.077 -17.489 -12.700 1.00 0.00 N +ATOM 1683 HZ1 LYS 180 -19.728 -16.981 -12.069 1.00 0.00 H +ATOM 1684 HZ2 LYS 180 -18.959 -16.950 -13.582 1.00 0.00 H +ATOM 1685 HZ3 LYS 180 -19.466 -18.428 -12.917 1.00 0.00 H +ATOM 1686 C LYS 180 -13.135 -13.815 -9.939 1.00 0.00 C +ATOM 1687 O LYS 180 -13.247 -13.100 -8.936 1.00 0.00 O +ATOM 1688 N ALA 181 -12.457 -13.452 -11.038 1.00 0.00 N +ATOM 1689 H ALA 181 -12.406 -14.055 -11.812 1.00 0.00 H +ATOM 1690 CA ALA 181 -11.754 -12.164 -11.181 1.00 0.00 C +ATOM 1691 CB ALA 181 -10.457 -12.356 -11.980 1.00 0.00 C +ATOM 1692 C ALA 181 -12.622 -11.044 -11.795 1.00 0.00 C +ATOM 1693 O ALA 181 -12.713 -10.911 -13.025 1.00 0.00 O +ATOM 1694 N LYS 182 -13.292 -10.285 -10.916 1.00 0.00 N +ATOM 1695 H LYS 182 -13.222 -10.461 -9.952 1.00 0.00 H +ATOM 1696 CA LYS 182 -14.168 -9.155 -11.284 1.00 0.00 C +ATOM 1697 CB LYS 182 -15.645 -9.470 -10.985 1.00 0.00 C +ATOM 1698 CG LYS 182 -16.268 -10.526 -11.891 1.00 0.00 C +ATOM 1699 CD LYS 182 -17.734 -10.758 -11.542 1.00 0.00 C +ATOM 1700 CE LYS 182 -18.388 -11.793 -12.454 1.00 0.00 C +ATOM 1701 NZ LYS 182 -17.872 -13.180 -12.251 1.00 0.00 N +ATOM 1702 HZ1 LYS 182 -18.358 -13.829 -12.901 1.00 0.00 H +ATOM 1703 HZ2 LYS 182 -18.049 -13.475 -11.269 1.00 0.00 H +ATOM 1704 HZ3 LYS 182 -16.850 -13.201 -12.440 1.00 0.00 H +ATOM 1705 C LYS 182 -13.739 -7.902 -10.508 1.00 0.00 C +ATOM 1706 O LYS 182 -13.724 -6.801 -11.071 1.00 0.00 O +ATOM 1707 N ASN 183 -13.397 -8.088 -9.224 1.00 0.00 N +ATOM 1708 H ASN 183 -13.430 -8.986 -8.826 1.00 0.00 H +ATOM 1709 CA ASN 183 -12.956 -7.010 -8.319 1.00 0.00 C +ATOM 1710 CB ASN 183 -13.897 -6.879 -7.089 1.00 0.00 C +ATOM 1711 CG ASN 183 -14.298 -8.230 -6.483 1.00 0.00 C +ATOM 1712 OD1 ASN 183 -15.339 -8.793 -6.828 1.00 0.00 O +ATOM 1713 ND2 ASN 183 -13.475 -8.744 -5.574 1.00 0.00 N +ATOM 1714 HD21 ASN 183 -13.718 -9.603 -5.170 1.00 0.00 H +ATOM 1715 HD22 ASN 183 -12.660 -8.255 -5.346 1.00 0.00 H +ATOM 1716 C ASN 183 -11.483 -7.143 -7.882 1.00 0.00 C +ATOM 1717 O ASN 183 -10.701 -6.203 -8.066 1.00 0.00 O +ATOM 1718 N LEU 184 -11.125 -8.305 -7.311 1.00 0.00 N +ATOM 1719 H LEU 184 -11.786 -9.023 -7.197 1.00 0.00 H +ATOM 1720 CA LEU 184 -9.761 -8.606 -6.823 1.00 0.00 C +ATOM 1721 CB LEU 184 -9.728 -8.632 -5.272 1.00 0.00 C +ATOM 1722 CG LEU 184 -9.819 -7.290 -4.518 1.00 0.00 C +ATOM 1723 CD1 LEU 184 -11.132 -7.173 -3.742 1.00 0.00 C +ATOM 1724 CD2 LEU 184 -8.636 -7.124 -3.571 1.00 0.00 C +ATOM 1725 C LEU 184 -9.205 -9.923 -7.390 1.00 0.00 C +ATOM 1726 O LEU 184 -9.978 -10.772 -7.851 1.00 0.00 O +ATOM 1727 N ALA 185 -7.871 -10.074 -7.347 1.00 0.00 N +ATOM 1728 H ALA 185 -7.308 -9.365 -6.966 1.00 0.00 H +ATOM 1729 CA ALA 185 -7.140 -11.259 -7.840 1.00 0.00 C +ATOM 1730 CB ALA 185 -5.806 -10.822 -8.464 1.00 0.00 C +ATOM 1731 C ALA 185 -6.929 -12.316 -6.727 1.00 0.00 C +ATOM 1732 O ALA 185 -7.892 -12.647 -6.028 1.00 0.00 O +ATOM 1733 N THR 186 -5.705 -12.860 -6.589 1.00 0.00 N +ATOM 1734 H THR 186 -4.963 -12.613 -7.177 1.00 0.00 H +ATOM 1735 CA THR 186 -5.354 -13.875 -5.568 1.00 0.00 C +ATOM 1736 CB THR 186 -5.406 -15.363 -6.152 1.00 0.00 C +ATOM 1737 OG1 THR 186 -4.939 -16.292 -5.166 1.00 0.00 O +ATOM 1738 HG1 THR 186 -5.534 -16.277 -4.418 1.00 0.00 H +ATOM 1739 CG2 THR 186 -4.586 -15.515 -7.452 1.00 0.00 C +ATOM 1740 C THR 186 -4.010 -13.583 -4.840 1.00 0.00 C +ATOM 1741 O THR 186 -2.939 -13.670 -5.451 1.00 0.00 O +ATOM 1742 N VAL 187 -4.093 -13.166 -3.566 1.00 0.00 N +ATOM 1743 H VAL 187 -4.973 -13.097 -3.150 1.00 0.00 H +ATOM 1744 CA VAL 187 -2.925 -12.853 -2.706 1.00 0.00 C +ATOM 1745 CB VAL 187 -3.344 -11.919 -1.473 1.00 0.00 C +ATOM 1746 CG1 VAL 187 -4.297 -12.640 -0.514 1.00 0.00 C +ATOM 1747 CG2 VAL 187 -2.114 -11.395 -0.711 1.00 0.00 C +ATOM 1748 C VAL 187 -2.116 -14.097 -2.239 1.00 0.00 C +ATOM 1749 O VAL 187 -0.885 -14.113 -2.354 1.00 0.00 O +ATOM 1750 N GLU 188 -2.834 -15.118 -1.747 1.00 0.00 N +ATOM 1751 H GLU 188 -3.815 -15.052 -1.732 1.00 0.00 H +ATOM 1752 CA GLU 188 -2.261 -16.371 -1.216 1.00 0.00 C +ATOM 1753 CB GLU 188 -3.306 -17.143 -0.399 1.00 0.00 C +ATOM 1754 CG GLU 188 -3.703 -16.486 0.919 1.00 0.00 C +ATOM 1755 CD GLU 188 -4.745 -17.284 1.681 1.00 0.00 C +ATOM 1756 OE1 GLU 188 -5.952 -17.046 1.467 1.00 0.00 O +ATOM 1757 OE2 GLU 188 -4.356 -18.147 2.496 1.00 0.00 O +ATOM 1758 C GLU 188 -1.586 -17.303 -2.236 1.00 0.00 C +ATOM 1759 O GLU 188 -0.522 -17.855 -1.941 1.00 0.00 O +ATOM 1760 N ASP 189 -2.184 -17.445 -3.429 1.00 0.00 N +ATOM 1761 H ASP 189 -3.021 -16.963 -3.611 1.00 0.00 H +ATOM 1762 CA ASP 189 -1.654 -18.297 -4.518 1.00 0.00 C +ATOM 1763 CB ASP 189 -2.702 -18.452 -5.639 1.00 0.00 C +ATOM 1764 CG ASP 189 -2.554 -19.757 -6.426 1.00 0.00 C +ATOM 1765 OD1 ASP 189 -3.168 -20.771 -6.027 1.00 0.00 O +ATOM 1766 OD2 ASP 189 -1.837 -19.761 -7.450 1.00 0.00 O +ATOM 1767 C ASP 189 -0.340 -17.700 -5.071 1.00 0.00 C +ATOM 1768 O ASP 189 0.626 -18.439 -5.305 1.00 0.00 O +ATOM 1769 N VAL 190 -0.322 -16.368 -5.247 1.00 0.00 N +ATOM 1770 H VAL 190 -1.131 -15.852 -5.031 1.00 0.00 H +ATOM 1771 CA VAL 190 0.848 -15.608 -5.742 1.00 0.00 C +ATOM 1772 CB VAL 190 0.453 -14.141 -6.182 1.00 0.00 C +ATOM 1773 CG1 VAL 190 1.658 -13.377 -6.744 1.00 0.00 C +ATOM 1774 CG2 VAL 190 -0.618 -14.194 -7.269 1.00 0.00 C +ATOM 1775 C VAL 190 1.967 -15.616 -4.671 1.00 0.00 C +ATOM 1776 O VAL 190 3.152 -15.707 -5.015 1.00 0.00 O +ATOM 1777 N ALA 191 1.567 -15.530 -3.392 1.00 0.00 N +ATOM 1778 H ALA 191 0.610 -15.441 -3.179 1.00 0.00 H +ATOM 1779 CA ALA 191 2.479 -15.547 -2.231 1.00 0.00 C +ATOM 1780 CB ALA 191 1.750 -15.096 -0.969 1.00 0.00 C +ATOM 1781 C ALA 191 3.137 -16.925 -2.016 1.00 0.00 C +ATOM 1782 O ALA 191 4.323 -16.999 -1.682 1.00 0.00 O +ATOM 1783 N LYS 192 2.354 -17.997 -2.213 1.00 0.00 N +ATOM 1784 H LYS 192 1.416 -17.866 -2.474 1.00 0.00 H +ATOM 1785 CA LYS 192 2.801 -19.402 -2.076 1.00 0.00 C +ATOM 1786 CB LYS 192 1.599 -20.357 -2.042 1.00 0.00 C +ATOM 1787 CG LYS 192 0.845 -20.402 -0.724 1.00 0.00 C +ATOM 1788 CD LYS 192 -0.352 -21.344 -0.817 1.00 0.00 C +ATOM 1789 CE LYS 192 -1.166 -21.378 0.473 1.00 0.00 C +ATOM 1790 NZ LYS 192 -1.891 -20.103 0.755 1.00 0.00 N +ATOM 1791 HZ1 LYS 192 -1.205 -19.326 0.841 1.00 0.00 H +ATOM 1792 HZ2 LYS 192 -2.423 -20.196 1.644 1.00 0.00 H +ATOM 1793 HZ3 LYS 192 -2.550 -19.899 -0.023 1.00 0.00 H +ATOM 1794 C LYS 192 3.783 -19.867 -3.168 1.00 0.00 C +ATOM 1795 O LYS 192 4.801 -20.494 -2.854 1.00 0.00 O +ATOM 1796 N LYS 193 3.465 -19.552 -4.433 1.00 0.00 N +ATOM 1797 H LYS 193 2.643 -19.038 -4.613 1.00 0.00 H +ATOM 1798 CA LYS 193 4.270 -19.925 -5.617 1.00 0.00 C +ATOM 1799 CB LYS 193 3.442 -19.769 -6.901 1.00 0.00 C +ATOM 1800 CG LYS 193 2.343 -20.809 -7.081 1.00 0.00 C +ATOM 1801 CD LYS 193 1.600 -20.609 -8.397 1.00 0.00 C +ATOM 1802 CE LYS 193 0.521 -21.667 -8.617 1.00 0.00 C +ATOM 1803 NZ LYS 193 1.067 -23.037 -8.859 1.00 0.00 N +ATOM 1804 HZ1 LYS 193 0.281 -23.703 -9.000 1.00 0.00 H +ATOM 1805 HZ2 LYS 193 1.632 -23.335 -8.039 1.00 0.00 H +ATOM 1806 HZ3 LYS 193 1.667 -23.025 -9.708 1.00 0.00 H +ATOM 1807 C LYS 193 5.638 -19.240 -5.796 1.00 0.00 C +ATOM 1808 O LYS 193 6.629 -19.926 -6.075 1.00 0.00 O +ATOM 1809 N TYR 194 5.685 -17.907 -5.636 1.00 0.00 N +ATOM 1810 H TYR 194 4.872 -17.409 -5.401 1.00 0.00 H +ATOM 1811 CA TYR 194 6.919 -17.106 -5.792 1.00 0.00 C +ATOM 1812 CB TYR 194 7.083 -16.609 -7.264 1.00 0.00 C +ATOM 1813 CG TYR 194 5.861 -15.990 -7.960 1.00 0.00 C +ATOM 1814 CD1 TYR 194 5.695 -14.586 -8.028 1.00 0.00 C +ATOM 1815 CE1 TYR 194 4.595 -14.005 -8.717 1.00 0.00 C +ATOM 1816 CD2 TYR 194 4.891 -16.802 -8.600 1.00 0.00 C +ATOM 1817 CE2 TYR 194 3.788 -16.230 -9.290 1.00 0.00 C +ATOM 1818 CZ TYR 194 3.650 -14.834 -9.342 1.00 0.00 C +ATOM 1819 OH TYR 194 2.583 -14.278 -10.011 1.00 0.00 O +ATOM 1820 HH TYR 194 2.622 -13.320 -9.962 1.00 0.00 H +ATOM 1821 C TYR 194 7.080 -15.937 -4.803 1.00 0.00 C +ATOM 1822 O TYR 194 8.181 -15.385 -4.668 1.00 0.00 O +ATOM 1823 N GLY 195 5.999 -15.598 -4.091 1.00 0.00 N +ATOM 1824 H GLY 195 5.150 -16.080 -4.199 1.00 0.00 H +ATOM 1825 CA GLY 195 6.015 -14.503 -3.122 1.00 0.00 C +ATOM 1826 C GLY 195 6.500 -14.882 -1.729 1.00 0.00 C +ATOM 1827 O GLY 195 6.259 -14.150 -0.762 1.00 0.00 O +ATOM 1828 N ALA 196 7.178 -16.038 -1.648 1.00 0.00 N +ATOM 1829 H ALA 196 7.302 -16.563 -2.466 1.00 0.00 H +ATOM 1830 CA ALA 196 7.774 -16.630 -0.427 1.00 0.00 C +ATOM 1831 CB ALA 196 8.877 -15.708 0.149 1.00 0.00 C +ATOM 1832 C ALA 196 6.832 -17.149 0.690 1.00 0.00 C +ATOM 1833 O ALA 196 5.813 -17.783 0.390 1.00 0.00 O +ATOM 1834 N LYS 197 7.190 -16.881 1.956 1.00 0.00 N +ATOM 1835 H LYS 197 7.988 -16.356 2.169 1.00 0.00 H +ATOM 1836 CA LYS 197 6.458 -17.316 3.160 1.00 0.00 C +ATOM 1837 CB LYS 197 7.456 -17.709 4.255 1.00 0.00 C +ATOM 1838 CG LYS 197 8.238 -18.990 3.980 1.00 0.00 C +ATOM 1839 CD LYS 197 9.204 -19.305 5.117 1.00 0.00 C +ATOM 1840 CE LYS 197 9.999 -20.584 4.861 1.00 0.00 C +ATOM 1841 NZ LYS 197 10.982 -20.463 3.743 1.00 0.00 N +ATOM 1842 HZ1 LYS 197 11.485 -21.366 3.625 1.00 0.00 H +ATOM 1843 HZ2 LYS 197 10.479 -20.229 2.863 1.00 0.00 H +ATOM 1844 HZ3 LYS 197 11.666 -19.711 3.961 1.00 0.00 H +ATOM 1845 C LYS 197 5.433 -16.325 3.740 1.00 0.00 C +ATOM 1846 O LYS 197 5.650 -15.107 3.700 1.00 0.00 O +ATOM 1847 N TYR 198 4.316 -16.869 4.249 1.00 0.00 N +ATOM 1848 H TYR 198 4.183 -17.842 4.225 1.00 0.00 H +ATOM 1849 CA TYR 198 3.218 -16.102 4.869 1.00 0.00 C +ATOM 1850 CB TYR 198 1.899 -16.254 4.049 1.00 0.00 C +ATOM 1851 CG TYR 198 1.301 -17.668 3.925 1.00 0.00 C +ATOM 1852 CD1 TYR 198 1.784 -18.595 2.969 1.00 0.00 C +ATOM 1853 CE1 TYR 198 1.226 -19.899 2.859 1.00 0.00 C +ATOM 1854 CD2 TYR 198 0.239 -18.081 4.767 1.00 0.00 C +ATOM 1855 CE2 TYR 198 -0.324 -19.382 4.663 1.00 0.00 C +ATOM 1856 CZ TYR 198 0.176 -20.280 3.709 1.00 0.00 C +ATOM 1857 OH TYR 198 -0.366 -21.542 3.612 1.00 0.00 O +ATOM 1858 HH TYR 198 0.074 -22.041 2.919 1.00 0.00 H +ATOM 1859 C TYR 198 3.012 -16.531 6.340 1.00 0.00 C +ATOM 1860 O TYR 198 3.176 -17.718 6.650 1.00 0.00 O +ATOM 1861 N LEU 199 2.687 -15.574 7.225 1.00 0.00 N +ATOM 1862 H LEU 199 2.606 -14.642 6.940 1.00 0.00 H +ATOM 1863 CA LEU 199 2.448 -15.845 8.659 1.00 0.00 C +ATOM 1864 CB LEU 199 3.406 -15.016 9.572 1.00 0.00 C +ATOM 1865 CG LEU 199 3.637 -13.499 9.764 1.00 0.00 C +ATOM 1866 CD1 LEU 199 2.539 -12.830 10.596 1.00 0.00 C +ATOM 1867 CD2 LEU 199 4.950 -13.338 10.513 1.00 0.00 C +ATOM 1868 C LEU 199 0.972 -15.709 9.105 1.00 0.00 C +ATOM 1869 O LEU 199 0.339 -16.714 9.453 1.00 0.00 O +ATOM 1870 N ALA 200 0.454 -14.468 9.089 1.00 0.00 N +ATOM 1871 H ALA 200 1.021 -13.721 8.797 1.00 0.00 H +ATOM 1872 CA ALA 200 -0.923 -14.062 9.470 1.00 0.00 C +ATOM 1873 CB ALA 200 -1.822 -13.957 8.219 1.00 0.00 C +ATOM 1874 C ALA 200 -1.675 -14.785 10.633 1.00 0.00 C +ATOM 1875 O ALA 200 -1.973 -15.981 10.521 1.00 0.00 O +ATOM 1876 N PRO 201 -1.930 -14.080 11.782 1.00 0.00 N +ATOM 1877 CD PRO 201 -1.226 -12.822 12.111 1.00 0.00 C +ATOM 1878 CA PRO 201 -2.628 -14.543 13.000 1.00 0.00 C +ATOM 1879 CB PRO 201 -2.521 -13.320 13.909 1.00 0.00 C +ATOM 1880 CG PRO 201 -1.188 -12.833 13.618 1.00 0.00 C +ATOM 1881 C PRO 201 -4.104 -14.984 12.819 1.00 0.00 C +ATOM 1882 O PRO 201 -4.514 -15.313 11.703 1.00 0.00 O +ATOM 1883 N VAL 202 -4.865 -15.035 13.926 1.00 0.00 N +ATOM 1884 H VAL 202 -4.478 -14.800 14.798 1.00 0.00 H +ATOM 1885 CA VAL 202 -6.291 -15.429 13.940 1.00 0.00 C +ATOM 1886 CB VAL 202 -6.547 -16.756 14.771 1.00 0.00 C +ATOM 1887 CG1 VAL 202 -6.091 -17.964 13.967 1.00 0.00 C +ATOM 1888 CG2 VAL 202 -5.818 -16.733 16.135 1.00 0.00 C +ATOM 1889 C VAL 202 -7.251 -14.311 14.404 1.00 0.00 C +ATOM 1890 O VAL 202 -6.931 -13.563 15.338 1.00 0.00 O +ATOM 1891 N GLY 203 -8.399 -14.195 13.725 1.00 0.00 N +ATOM 1892 H GLY 203 -8.600 -14.790 12.971 1.00 0.00 H +ATOM 1893 CA GLY 203 -9.409 -13.198 14.069 1.00 0.00 C +ATOM 1894 C GLY 203 -9.887 -12.161 13.041 1.00 0.00 C +ATOM 1895 O GLY 203 -10.266 -11.079 13.503 1.00 0.00 O +ATOM 1896 N PRO 204 -9.883 -12.390 11.686 1.00 0.00 N +ATOM 1897 CD PRO 204 -10.619 -11.389 10.882 1.00 0.00 C +ATOM 1898 CA PRO 204 -9.489 -13.513 10.805 1.00 0.00 C +ATOM 1899 CB PRO 204 -10.021 -13.081 9.427 1.00 0.00 C +ATOM 1900 CG PRO 204 -11.186 -12.227 9.760 1.00 0.00 C +ATOM 1901 C PRO 204 -7.962 -13.729 10.763 1.00 0.00 C +ATOM 1902 O PRO 204 -7.490 -14.851 10.975 1.00 0.00 O +ATOM 1903 N TRP 205 -7.223 -12.659 10.423 1.00 0.00 N +ATOM 1904 H TRP 205 -7.671 -11.811 10.208 1.00 0.00 H +ATOM 1905 CA TRP 205 -5.746 -12.623 10.331 1.00 0.00 C +ATOM 1906 CB TRP 205 -5.243 -13.052 8.915 1.00 0.00 C +ATOM 1907 CG TRP 205 -5.939 -14.264 8.219 1.00 0.00 C +ATOM 1908 CD2 TRP 205 -5.536 -15.652 8.243 1.00 0.00 C +ATOM 1909 CE2 TRP 205 -6.463 -16.370 7.434 1.00 0.00 C +ATOM 1910 CE3 TRP 205 -4.484 -16.362 8.864 1.00 0.00 C +ATOM 1911 CD1 TRP 205 -7.058 -14.215 7.418 1.00 0.00 C +ATOM 1912 NE1 TRP 205 -7.372 -15.467 6.951 1.00 0.00 N +ATOM 1913 HE1 TRP 205 -8.129 -15.674 6.365 1.00 0.00 H +ATOM 1914 CZ2 TRP 205 -6.374 -17.769 7.228 1.00 0.00 C +ATOM 1915 CZ3 TRP 205 -4.392 -17.762 8.660 1.00 0.00 C +ATOM 1916 CH2 TRP 205 -5.338 -18.445 7.846 1.00 0.00 C +ATOM 1917 C TRP 205 -5.354 -11.149 10.622 1.00 0.00 C +ATOM 1918 O TRP 205 -4.788 -10.460 9.763 1.00 0.00 O +ATOM 1919 N ASP 206 -5.657 -10.685 11.844 1.00 0.00 N +ATOM 1920 H ASP 206 -6.069 -11.288 12.502 1.00 0.00 H +ATOM 1921 CA ASP 206 -5.411 -9.297 12.306 1.00 0.00 C +ATOM 1922 CB ASP 206 -6.348 -8.959 13.493 1.00 0.00 C +ATOM 1923 CG ASP 206 -6.303 -10.001 14.620 1.00 0.00 C +ATOM 1924 OD1 ASP 206 -7.105 -10.959 14.582 1.00 0.00 O +ATOM 1925 OD2 ASP 206 -5.476 -9.848 15.545 1.00 0.00 O +ATOM 1926 C ASP 206 -3.963 -8.827 12.607 1.00 0.00 C +ATOM 1927 O ASP 206 -3.072 -9.654 12.835 1.00 0.00 O +ATOM 1928 N ASP 207 -3.766 -7.492 12.597 1.00 0.00 N +ATOM 1929 H ASP 207 -4.525 -6.901 12.395 1.00 0.00 H +ATOM 1930 CA ASP 207 -2.494 -6.759 12.863 1.00 0.00 C +ATOM 1931 CB ASP 207 -2.189 -6.710 14.377 1.00 0.00 C +ATOM 1932 CG ASP 207 -3.222 -5.912 15.166 1.00 0.00 C +ATOM 1933 OD1 ASP 207 -3.032 -4.687 15.336 1.00 0.00 O +ATOM 1934 OD2 ASP 207 -4.215 -6.512 15.633 1.00 0.00 O +ATOM 1935 C ASP 207 -1.247 -7.186 12.056 1.00 0.00 C +ATOM 1936 O ASP 207 -1.181 -6.945 10.847 1.00 0.00 O +ATOM 1937 N TYR 208 -0.260 -7.786 12.742 1.00 0.00 N +ATOM 1938 H TYR 208 -0.314 -7.942 13.706 1.00 0.00 H +ATOM 1939 CA TYR 208 1.010 -8.316 12.198 1.00 0.00 C +ATOM 1940 CB TYR 208 0.779 -9.753 11.659 1.00 0.00 C +ATOM 1941 CG TYR 208 0.117 -9.928 10.286 1.00 0.00 C +ATOM 1942 CD1 TYR 208 -1.281 -10.096 10.154 1.00 0.00 C +ATOM 1943 CE1 TYR 208 -1.866 -10.392 8.902 1.00 0.00 C +ATOM 1944 CD2 TYR 208 0.905 -10.042 9.120 1.00 0.00 C +ATOM 1945 CE2 TYR 208 0.328 -10.326 7.879 1.00 0.00 C +ATOM 1946 CZ TYR 208 -1.048 -10.510 7.775 1.00 0.00 C +ATOM 1947 OH TYR 208 -1.574 -10.876 6.565 1.00 0.00 O +ATOM 1948 HH TYR 208 -2.472 -11.179 6.677 1.00 0.00 H +ATOM 1949 C TYR 208 1.880 -7.511 11.201 1.00 0.00 C +ATOM 1950 O TYR 208 1.484 -6.431 10.746 1.00 0.00 O +ATOM 1951 N SER 209 3.057 -8.083 10.884 1.00 0.00 N +ATOM 1952 H SER 209 3.301 -8.937 11.307 1.00 0.00 H +ATOM 1953 CA SER 209 4.071 -7.566 9.941 1.00 0.00 C +ATOM 1954 CB SER 209 4.658 -6.232 10.413 1.00 0.00 C +ATOM 1955 OG SER 209 5.479 -5.638 9.420 1.00 0.00 O +ATOM 1956 HG SER 209 5.829 -4.806 9.748 1.00 0.00 H +ATOM 1957 C SER 209 5.208 -8.597 9.832 1.00 0.00 C +ATOM 1958 O SER 209 5.635 -9.157 10.851 1.00 0.00 O +ATOM 1959 N ILE 210 5.665 -8.862 8.599 1.00 0.00 N +ATOM 1960 H ILE 210 5.272 -8.418 7.816 1.00 0.00 H +ATOM 1961 CA ILE 210 6.763 -9.812 8.321 1.00 0.00 C +ATOM 1962 CB ILE 210 6.221 -11.177 7.665 1.00 0.00 C +ATOM 1963 CG2 ILE 210 5.471 -10.890 6.348 1.00 0.00 C +ATOM 1964 CG1 ILE 210 7.347 -12.232 7.546 1.00 0.00 C +ATOM 1965 CD1 ILE 210 6.891 -13.701 7.536 1.00 0.00 C +ATOM 1966 C ILE 210 7.850 -9.126 7.454 1.00 0.00 C +ATOM 1967 O ILE 210 7.539 -8.524 6.417 1.00 0.00 O +ATOM 1968 N THR 211 9.098 -9.172 7.939 1.00 0.00 N +ATOM 1969 H THR 211 9.277 -9.594 8.808 1.00 0.00 H +ATOM 1970 CA THR 211 10.279 -8.617 7.253 1.00 0.00 C +ATOM 1971 CB THR 211 10.811 -7.323 7.954 1.00 0.00 C +ATOM 1972 OG1 THR 211 9.713 -6.615 8.541 1.00 0.00 O +ATOM 1973 HG1 THR 211 10.045 -5.816 8.955 1.00 0.00 H +ATOM 1974 CG2 THR 211 11.498 -6.390 6.944 1.00 0.00 C +ATOM 1975 C THR 211 11.349 -9.728 7.264 1.00 0.00 C +ATOM 1976 O THR 211 11.529 -10.403 8.289 1.00 0.00 O +ATOM 1977 N ASP 212 12.006 -9.942 6.116 1.00 0.00 N +ATOM 1978 H ASP 212 11.802 -9.407 5.318 1.00 0.00 H +ATOM 1979 CA ASP 212 13.056 -10.966 5.959 1.00 0.00 C +ATOM 1980 CB ASP 212 12.555 -12.121 5.063 1.00 0.00 C +ATOM 1981 CG ASP 212 13.218 -13.463 5.386 1.00 0.00 C +ATOM 1982 OD1 ASP 212 14.268 -13.774 4.781 1.00 0.00 O +ATOM 1983 OD2 ASP 212 12.679 -14.211 6.231 1.00 0.00 O +ATOM 1984 C ASP 212 14.327 -10.342 5.365 1.00 0.00 C +ATOM 1985 O ASP 212 15.438 -10.772 5.694 1.00 0.00 O +ATOM 1986 N GLY 213 14.150 -9.334 4.506 1.00 0.00 N +ATOM 1987 H GLY 213 13.252 -9.010 4.276 1.00 0.00 H +ATOM 1988 CA GLY 213 15.277 -8.665 3.868 1.00 0.00 C +ATOM 1989 C GLY 213 15.067 -7.183 3.611 1.00 0.00 C +ATOM 1990 O GLY 213 15.210 -6.369 4.532 1.00 0.00 O +ATOM 1991 N ARG 214 14.728 -6.846 2.361 1.00 0.00 N +ATOM 1992 H ARG 214 14.618 -7.555 1.700 1.00 0.00 H +ATOM 1993 CA ARG 214 14.495 -5.464 1.906 1.00 0.00 C +ATOM 1994 CB ARG 214 15.191 -5.220 0.553 1.00 0.00 C +ATOM 1995 CG ARG 214 16.716 -5.201 0.612 1.00 0.00 C +ATOM 1996 CD ARG 214 17.319 -4.956 -0.762 1.00 0.00 C +ATOM 1997 NE ARG 214 18.783 -4.934 -0.725 1.00 0.00 N +ATOM 1998 HE ARG 214 19.225 -5.073 0.139 1.00 0.00 H +ATOM 1999 CZ ARG 214 19.575 -4.740 -1.780 1.00 0.00 C +ATOM 2000 NH1 ARG 214 20.891 -4.742 -1.619 1.00 0.00 N +ATOM 2001 HH11 ARG 214 21.283 -4.890 -0.711 1.00 0.00 H +ATOM 2002 HH12 ARG 214 21.492 -4.597 -2.405 1.00 0.00 H +ATOM 2003 NH2 ARG 214 19.069 -4.542 -2.994 1.00 0.00 N +ATOM 2004 HH21 ARG 214 18.078 -4.538 -3.128 1.00 0.00 H +ATOM 2005 HH22 ARG 214 19.680 -4.398 -3.773 1.00 0.00 H +ATOM 2006 C ARG 214 13.000 -5.103 1.804 1.00 0.00 C +ATOM 2007 O ARG 214 12.656 -3.930 1.609 1.00 0.00 O +ATOM 2008 N LEU 215 12.126 -6.109 1.952 1.00 0.00 N +ATOM 2009 H LEU 215 12.441 -7.025 2.117 1.00 0.00 H +ATOM 2010 CA LEU 215 10.665 -5.925 1.879 1.00 0.00 C +ATOM 2011 CB LEU 215 10.042 -6.847 0.808 1.00 0.00 C +ATOM 2012 CG LEU 215 10.079 -6.392 -0.659 1.00 0.00 C +ATOM 2013 CD1 LEU 215 11.004 -7.280 -1.499 1.00 0.00 C +ATOM 2014 CD2 LEU 215 8.661 -6.419 -1.217 1.00 0.00 C +ATOM 2015 C LEU 215 9.917 -6.072 3.214 1.00 0.00 C +ATOM 2016 O LEU 215 10.100 -7.061 3.937 1.00 0.00 O +ATOM 2017 N VAL 216 9.105 -5.052 3.527 1.00 0.00 N +ATOM 2018 H VAL 216 9.025 -4.280 2.923 1.00 0.00 H +ATOM 2019 CA VAL 216 8.274 -4.957 4.745 1.00 0.00 C +ATOM 2020 CB VAL 216 8.837 -3.854 5.761 1.00 0.00 C +ATOM 2021 CG1 VAL 216 8.850 -2.439 5.142 1.00 0.00 C +ATOM 2022 CG2 VAL 216 8.092 -3.886 7.105 1.00 0.00 C +ATOM 2023 C VAL 216 6.811 -4.694 4.313 1.00 0.00 C +ATOM 2024 O VAL 216 6.583 -4.008 3.308 1.00 0.00 O +ATOM 2025 N THR 217 5.851 -5.270 5.054 1.00 0.00 N +ATOM 2026 H THR 217 6.089 -5.825 5.828 1.00 0.00 H +ATOM 2027 CA THR 217 4.405 -5.125 4.783 1.00 0.00 C +ATOM 2028 CB THR 217 3.686 -6.513 4.662 1.00 0.00 C +ATOM 2029 OG1 THR 217 3.918 -7.286 5.848 1.00 0.00 O +ATOM 2030 HG1 THR 217 4.855 -7.476 5.948 1.00 0.00 H +ATOM 2031 CG2 THR 217 4.203 -7.281 3.456 1.00 0.00 C +ATOM 2032 C THR 217 3.684 -4.253 5.827 1.00 0.00 C +ATOM 2033 O THR 217 3.196 -3.170 5.493 1.00 0.00 O +ATOM 2034 N GLY 218 3.602 -4.728 7.076 1.00 0.00 N +ATOM 2035 H GLY 218 3.986 -5.601 7.309 1.00 0.00 H +ATOM 2036 CA GLY 218 2.944 -3.982 8.145 1.00 0.00 C +ATOM 2037 C GLY 218 1.430 -4.059 8.183 1.00 0.00 C +ATOM 2038 O GLY 218 0.837 -4.261 9.246 1.00 0.00 O +ATOM 2039 N VAL 219 0.826 -3.927 6.994 1.00 0.00 N +ATOM 2040 H VAL 219 1.378 -3.780 6.200 1.00 0.00 H +ATOM 2041 CA VAL 219 -0.629 -3.964 6.712 1.00 0.00 C +ATOM 2042 CB VAL 219 -1.189 -5.440 6.490 1.00 0.00 C +ATOM 2043 CG1 VAL 219 -0.522 -6.042 5.280 1.00 0.00 C +ATOM 2044 CG2 VAL 219 -0.971 -6.353 7.712 1.00 0.00 C +ATOM 2045 C VAL 219 -1.611 -3.098 7.533 1.00 0.00 C +ATOM 2046 O VAL 219 -1.586 -3.128 8.767 1.00 0.00 O +ATOM 2047 N ASN 220 -2.467 -2.347 6.816 1.00 0.00 N +ATOM 2048 H ASN 220 -2.427 -2.379 5.834 1.00 0.00 H +ATOM 2049 CA ASN 220 -3.518 -1.430 7.339 1.00 0.00 C +ATOM 2050 CB ASN 220 -4.519 -2.170 8.247 1.00 0.00 C +ATOM 2051 CG ASN 220 -5.573 -2.908 7.457 1.00 0.00 C +ATOM 2052 OD1 ASN 220 -6.743 -2.524 7.455 1.00 0.00 O +ATOM 2053 ND2 ASN 220 -5.168 -3.982 6.781 1.00 0.00 N +ATOM 2054 HD21 ASN 220 -5.792 -4.509 6.261 1.00 0.00 H +ATOM 2055 HD22 ASN 220 -4.217 -4.222 6.827 1.00 0.00 H +ATOM 2056 C ASN 220 -3.085 -0.087 7.977 1.00 0.00 C +ATOM 2057 O ASN 220 -2.004 -0.023 8.574 1.00 0.00 O +ATOM 2058 N PRO 221 -3.921 1.001 7.857 1.00 0.00 N +ATOM 2059 CD PRO 221 -5.176 1.098 7.070 1.00 0.00 C +ATOM 2060 CA PRO 221 -3.601 2.329 8.428 1.00 0.00 C +ATOM 2061 CB PRO 221 -4.753 3.210 7.911 1.00 0.00 C +ATOM 2062 CG PRO 221 -5.887 2.249 7.710 1.00 0.00 C +ATOM 2063 C PRO 221 -3.420 2.407 9.970 1.00 0.00 C +ATOM 2064 O PRO 221 -3.025 3.454 10.504 1.00 0.00 O +ATOM 2065 N ALA 222 -3.686 1.280 10.645 1.00 0.00 N +ATOM 2066 H ALA 222 -3.993 0.478 10.170 1.00 0.00 H +ATOM 2067 CA ALA 222 -3.563 1.126 12.105 1.00 0.00 C +ATOM 2068 CB ALA 222 -4.642 0.179 12.621 1.00 0.00 C +ATOM 2069 C ALA 222 -2.173 0.572 12.452 1.00 0.00 C +ATOM 2070 O ALA 222 -1.673 0.783 13.565 1.00 0.00 O +ATOM 2071 N SER 223 -1.569 -0.125 11.479 1.00 0.00 N +ATOM 2072 H SER 223 -2.010 -0.251 10.610 1.00 0.00 H +ATOM 2073 CA SER 223 -0.241 -0.747 11.598 1.00 0.00 C +ATOM 2074 CB SER 223 -0.353 -2.260 11.370 1.00 0.00 C +ATOM 2075 OG SER 223 -1.215 -2.857 12.323 1.00 0.00 O +ATOM 2076 HG SER 223 -1.268 -3.801 12.160 1.00 0.00 H +ATOM 2077 C SER 223 0.779 -0.119 10.626 1.00 0.00 C +ATOM 2078 O SER 223 1.851 -0.693 10.378 1.00 0.00 O +ATOM 2079 N ALA 224 0.451 1.080 10.118 1.00 0.00 N +ATOM 2080 H ALA 224 -0.405 1.495 10.362 1.00 0.00 H +ATOM 2081 CA ALA 224 1.293 1.864 9.186 1.00 0.00 C +ATOM 2082 CB ALA 224 0.535 3.089 8.681 1.00 0.00 C +ATOM 2083 C ALA 224 2.591 2.287 9.892 1.00 0.00 C +ATOM 2084 O ALA 224 3.655 2.360 9.264 1.00 0.00 O +ATOM 2085 N HIS 225 2.469 2.555 11.201 1.00 0.00 N +ATOM 2086 H HIS 225 1.580 2.484 11.619 1.00 0.00 H +ATOM 2087 CA HIS 225 3.568 2.956 12.102 1.00 0.00 C +ATOM 2088 CB HIS 225 3.009 3.306 13.498 1.00 0.00 C +ATOM 2089 CG HIS 225 3.844 4.284 14.277 1.00 0.00 C +ATOM 2090 CD2 HIS 225 3.593 5.556 14.672 1.00 0.00 C +ATOM 2091 ND1 HIS 225 5.099 3.978 14.760 1.00 0.00 N +ATOM 2092 HD1 HIS 225 5.565 3.124 14.639 1.00 0.00 H +ATOM 2093 CE1 HIS 225 5.585 5.016 15.418 1.00 0.00 C +ATOM 2094 NE2 HIS 225 4.690 5.987 15.379 1.00 0.00 N +ATOM 2095 HE2 HIS 225 4.792 6.871 15.788 1.00 0.00 H +ATOM 2096 C HIS 225 4.618 1.825 12.203 1.00 0.00 C +ATOM 2097 O HIS 225 5.816 2.104 12.320 1.00 0.00 O +ATOM 2098 N SER 226 4.145 0.568 12.159 1.00 0.00 N +ATOM 2099 H SER 226 3.176 0.424 12.076 1.00 0.00 H +ATOM 2100 CA SER 226 4.986 -0.650 12.225 1.00 0.00 C +ATOM 2101 CB SER 226 4.103 -1.905 12.362 1.00 0.00 C +ATOM 2102 OG SER 226 4.877 -3.067 12.617 1.00 0.00 O +ATOM 2103 HG SER 226 4.297 -3.827 12.697 1.00 0.00 H +ATOM 2104 C SER 226 5.898 -0.764 10.982 1.00 0.00 C +ATOM 2105 O SER 226 7.092 -1.068 11.111 1.00 0.00 O +ATOM 2106 N THR 227 5.325 -0.485 9.799 1.00 0.00 N +ATOM 2107 H THR 227 4.372 -0.239 9.790 1.00 0.00 H +ATOM 2108 CA THR 227 6.031 -0.513 8.499 1.00 0.00 C +ATOM 2109 CB THR 227 5.030 -0.394 7.303 1.00 0.00 C +ATOM 2110 OG1 THR 227 3.760 -0.935 7.685 1.00 0.00 O +ATOM 2111 HG1 THR 227 3.146 -0.862 6.951 1.00 0.00 H +ATOM 2112 CG2 THR 227 5.541 -1.166 6.077 1.00 0.00 C +ATOM 2113 C THR 227 7.045 0.653 8.441 1.00 0.00 C +ATOM 2114 O THR 227 8.169 0.482 7.952 1.00 0.00 O +ATOM 2115 N ALA 228 6.630 1.811 8.980 1.00 0.00 N +ATOM 2116 H ALA 228 5.730 1.869 9.371 1.00 0.00 H +ATOM 2117 CA ALA 228 7.427 3.048 9.038 1.00 0.00 C +ATOM 2118 CB ALA 228 6.540 4.217 9.416 1.00 0.00 C +ATOM 2119 C ALA 228 8.634 2.964 9.988 1.00 0.00 C +ATOM 2120 O ALA 228 9.717 3.453 9.646 1.00 0.00 O +ATOM 2121 N VAL 229 8.441 2.330 11.157 1.00 0.00 N +ATOM 2122 H VAL 229 7.556 1.951 11.353 1.00 0.00 H +ATOM 2123 CA VAL 229 9.497 2.147 12.178 1.00 0.00 C +ATOM 2124 CB VAL 229 8.890 1.750 13.597 1.00 0.00 C +ATOM 2125 CG1 VAL 229 8.364 0.310 13.629 1.00 0.00 C +ATOM 2126 CG2 VAL 229 9.893 2.019 14.730 1.00 0.00 C +ATOM 2127 C VAL 229 10.585 1.169 11.659 1.00 0.00 C +ATOM 2128 O VAL 229 11.782 1.402 11.864 1.00 0.00 O +ATOM 2129 N ARG 230 10.139 0.100 10.983 1.00 0.00 N +ATOM 2130 H ARG 230 9.166 -0.041 10.876 1.00 0.00 H +ATOM 2131 CA ARG 230 11.011 -0.928 10.380 1.00 0.00 C +ATOM 2132 CB ARG 230 10.201 -2.164 9.969 1.00 0.00 C +ATOM 2133 CG ARG 230 9.714 -3.003 11.148 1.00 0.00 C +ATOM 2134 CD ARG 230 8.995 -4.261 10.692 1.00 0.00 C +ATOM 2135 NE ARG 230 8.582 -5.095 11.824 1.00 0.00 N +ATOM 2136 HE ARG 230 8.677 -4.726 12.727 1.00 0.00 H +ATOM 2137 CZ ARG 230 8.082 -6.327 11.729 1.00 0.00 C +ATOM 2138 NH1 ARG 230 7.745 -6.982 12.832 1.00 0.00 N +ATOM 2139 HH11 ARG 230 7.867 -6.551 13.726 1.00 0.00 H +ATOM 2140 HH12 ARG 230 7.369 -7.907 12.769 1.00 0.00 H +ATOM 2141 NH2 ARG 230 7.912 -6.913 10.547 1.00 0.00 N +ATOM 2142 HH21 ARG 230 8.161 -6.429 9.709 1.00 0.00 H +ATOM 2143 HH22 ARG 230 7.535 -7.838 10.497 1.00 0.00 H +ATOM 2144 C ARG 230 11.797 -0.367 9.181 1.00 0.00 C +ATOM 2145 O ARG 230 12.966 -0.721 8.982 1.00 0.00 O +ATOM 2146 N SER 231 11.144 0.521 8.412 1.00 0.00 N +ATOM 2147 H SER 231 10.212 0.755 8.629 1.00 0.00 H +ATOM 2148 CA SER 231 11.721 1.190 7.227 1.00 0.00 C +ATOM 2149 CB SER 231 10.622 1.898 6.416 1.00 0.00 C +ATOM 2150 OG SER 231 11.114 2.392 5.180 1.00 0.00 O +ATOM 2151 HG SER 231 10.403 2.825 4.703 1.00 0.00 H +ATOM 2152 C SER 231 12.841 2.181 7.609 1.00 0.00 C +ATOM 2153 O SER 231 13.904 2.171 6.977 1.00 0.00 O +ATOM 2154 N ILE 232 12.606 3.004 8.648 1.00 0.00 N +ATOM 2155 H ILE 232 11.741 2.965 9.115 1.00 0.00 H +ATOM 2156 CA ILE 232 13.596 3.991 9.142 1.00 0.00 C +ATOM 2157 CB ILE 232 12.973 5.115 10.075 1.00 0.00 C +ATOM 2158 CG2 ILE 232 12.051 6.019 9.254 1.00 0.00 C +ATOM 2159 CG1 ILE 232 12.234 4.533 11.294 1.00 0.00 C +ATOM 2160 CD1 ILE 232 12.656 5.120 12.645 1.00 0.00 C +ATOM 2161 C ILE 232 14.820 3.317 9.802 1.00 0.00 C +ATOM 2162 O ILE 232 15.957 3.766 9.615 1.00 0.00 O +ATOM 2163 N ASP 233 14.560 2.218 10.527 1.00 0.00 N +ATOM 2164 H ASP 233 13.626 1.914 10.628 1.00 0.00 H +ATOM 2165 CA ASP 233 15.581 1.407 11.222 1.00 0.00 C +ATOM 2166 CB ASP 233 14.901 0.379 12.149 1.00 0.00 C +ATOM 2167 CG ASP 233 15.777 -0.034 13.335 1.00 0.00 C +ATOM 2168 OD1 ASP 233 15.691 0.618 14.399 1.00 0.00 O +ATOM 2169 OD2 ASP 233 16.537 -1.018 13.206 1.00 0.00 O +ATOM 2170 C ASP 233 16.464 0.695 10.174 1.00 0.00 C +ATOM 2171 O ASP 233 17.675 0.545 10.379 1.00 0.00 O +ATOM 2172 N ALA 234 15.834 0.269 9.067 1.00 0.00 N +ATOM 2173 H ALA 234 14.862 0.399 8.974 1.00 0.00 H +ATOM 2174 CA ALA 234 16.491 -0.419 7.937 1.00 0.00 C +ATOM 2175 CB ALA 234 15.442 -1.038 7.017 1.00 0.00 C +ATOM 2176 C ALA 234 17.438 0.490 7.130 1.00 0.00 C +ATOM 2177 O ALA 234 18.567 0.084 6.831 1.00 0.00 O +ATOM 2178 N LEU 235 16.971 1.703 6.788 1.00 0.00 N +ATOM 2179 H LEU 235 16.058 1.971 7.037 1.00 0.00 H +ATOM 2180 CA LEU 235 17.758 2.700 6.031 1.00 0.00 C +ATOM 2181 CB LEU 235 16.854 3.792 5.395 1.00 0.00 C +ATOM 2182 CG LEU 235 15.827 4.731 6.063 1.00 0.00 C +ATOM 2183 CD1 LEU 235 16.483 5.975 6.679 1.00 0.00 C +ATOM 2184 CD2 LEU 235 14.816 5.162 5.012 1.00 0.00 C +ATOM 2185 C LEU 235 18.932 3.324 6.817 1.00 0.00 C +ATOM 2186 O LEU 235 20.024 3.487 6.266 1.00 0.00 O +ATOM 2187 N LYS 236 18.684 3.659 8.092 1.00 0.00 N +ATOM 2188 H LYS 236 17.787 3.503 8.469 1.00 0.00 H +ATOM 2189 CA LYS 236 19.678 4.261 9.010 1.00 0.00 C +ATOM 2190 CB LYS 236 18.993 4.807 10.271 1.00 0.00 C +ATOM 2191 CG LYS 236 18.183 6.079 10.058 1.00 0.00 C +ATOM 2192 CD LYS 236 17.566 6.563 11.366 1.00 0.00 C +ATOM 2193 CE LYS 236 16.774 7.855 11.190 1.00 0.00 C +ATOM 2194 NZ LYS 236 17.627 9.041 10.878 1.00 0.00 N +ATOM 2195 HZ1 LYS 236 18.146 8.872 9.993 1.00 0.00 H +ATOM 2196 HZ2 LYS 236 18.303 9.195 11.653 1.00 0.00 H +ATOM 2197 HZ3 LYS 236 17.025 9.883 10.771 1.00 0.00 H +ATOM 2198 C LYS 236 20.822 3.314 9.415 1.00 0.00 C +ATOM 2199 O LYS 236 21.974 3.750 9.515 1.00 0.00 O +ATOM 2200 N ASN 237 20.483 2.026 9.609 1.00 0.00 N +ATOM 2201 H ASN 237 19.547 1.755 9.483 1.00 0.00 H +ATOM 2202 CA ASN 237 21.380 0.902 10.006 1.00 0.00 C +ATOM 2203 CB ASN 237 21.801 0.038 8.783 1.00 0.00 C +ATOM 2204 CG ASN 237 22.455 0.849 7.658 1.00 0.00 C +ATOM 2205 OD1 ASN 237 21.777 1.331 6.749 1.00 0.00 O +ATOM 2206 ND2 ASN 237 23.776 0.986 7.715 1.00 0.00 N +ATOM 2207 HD21 ASN 237 24.268 0.573 8.457 1.00 0.00 H +ATOM 2208 HD22 ASN 237 24.211 1.501 7.004 1.00 0.00 H +ATOM 2209 C ASN 237 22.582 1.158 10.951 1.00 0.00 C +ATOM 2210 O ASN 237 23.478 1.947 10.625 1.00 0.00 O +ATOM 2211 N HIS 238 22.583 0.460 12.102 1.00 0.00 N +ATOM 2212 H HIS 238 21.845 -0.163 12.285 1.00 0.00 H +ATOM 2213 CA HIS 238 23.606 0.515 13.183 1.00 0.00 C +ATOM 2214 CB HIS 238 24.978 -0.042 12.705 1.00 0.00 C +ATOM 2215 CG HIS 238 25.785 -0.719 13.779 1.00 0.00 C +ATOM 2216 CD2 HIS 238 26.147 -2.015 13.940 1.00 0.00 C +ATOM 2217 ND1 HIS 238 26.336 -0.036 14.843 1.00 0.00 N +ATOM 2218 HD1 HIS 238 26.252 0.926 15.009 1.00 0.00 H +ATOM 2219 CE1 HIS 238 27.001 -0.880 15.612 1.00 0.00 C +ATOM 2220 NE2 HIS 238 26.901 -2.087 15.086 1.00 0.00 N +ATOM 2221 HE2 HIS 238 27.301 -2.902 15.454 1.00 0.00 H +ATOM 2222 C HIS 238 23.769 1.897 13.864 1.00 0.00 C +ATOM 2223 O HIS 238 23.608 2.001 15.085 1.00 0.00 O +ATOM 2224 N HIS 239 24.073 2.936 13.063 1.00 0.00 N +ATOM 2225 H HIS 239 24.201 2.788 12.106 1.00 0.00 H +ATOM 2226 CA HIS 239 24.278 4.352 13.479 1.00 0.00 C +ATOM 2227 CB HIS 239 22.950 5.003 13.958 1.00 0.00 C +ATOM 2228 CG HIS 239 22.835 6.474 13.663 1.00 0.00 C +ATOM 2229 CD2 HIS 239 22.800 7.549 14.487 1.00 0.00 C +ATOM 2230 ND1 HIS 239 22.717 6.972 12.383 1.00 0.00 N +ATOM 2231 HD1 HIS 239 22.709 6.439 11.560 1.00 0.00 H +ATOM 2232 CE1 HIS 239 22.616 8.289 12.429 1.00 0.00 C +ATOM 2233 NE2 HIS 239 22.664 8.664 13.695 1.00 0.00 N +ATOM 2234 HE2 HIS 239 22.610 9.588 14.017 1.00 0.00 H +ATOM 2235 C HIS 239 25.408 4.579 14.513 1.00 0.00 C +ATOM 2236 O HIS 239 25.513 3.836 15.498 1.00 0.00 O +ATOM 2237 N HIS 240 26.234 5.606 14.267 1.00 0.00 N +ATOM 2238 H HIS 240 26.106 6.165 13.469 1.00 0.00 H +ATOM 2239 CA HIS 240 27.368 5.984 15.130 1.00 0.00 C +ATOM 2240 CB HIS 240 28.663 6.094 14.284 1.00 0.00 C +ATOM 2241 CG HIS 240 29.938 5.970 15.072 1.00 0.00 C +ATOM 2242 CD2 HIS 240 30.879 4.994 15.102 1.00 0.00 C +ATOM 2243 ND1 HIS 240 30.379 6.949 15.938 1.00 0.00 N +ATOM 2244 HD1 HIS 240 29.914 7.788 16.135 1.00 0.00 H +ATOM 2245 CE1 HIS 240 31.533 6.583 16.466 1.00 0.00 C +ATOM 2246 NE2 HIS 240 31.858 5.400 15.976 1.00 0.00 N +ATOM 2247 HE2 HIS 240 32.667 4.895 16.199 1.00 0.00 H +ATOM 2248 C HIS 240 27.053 7.315 15.855 1.00 0.00 C +ATOM 2249 O HIS 240 26.851 8.351 15.205 1.00 0.00 O +ATOM 2250 N HIS 241 26.967 7.249 17.191 1.00 0.00 N +ATOM 2251 H HIS 241 27.097 6.394 17.657 1.00 0.00 H +ATOM 2252 CA HIS 241 26.680 8.409 18.058 1.00 0.00 C +ATOM 2253 CB HIS 241 25.312 8.252 18.783 1.00 0.00 C +ATOM 2254 CG HIS 241 25.092 6.913 19.433 1.00 0.00 C +ATOM 2255 CD2 HIS 241 24.225 5.911 19.144 1.00 0.00 C +ATOM 2256 ND1 HIS 241 25.805 6.491 20.536 1.00 0.00 N +ATOM 2257 HD1 HIS 241 26.512 6.998 20.987 1.00 0.00 H +ATOM 2258 CE1 HIS 241 25.389 5.290 20.898 1.00 0.00 C +ATOM 2259 NE2 HIS 241 24.431 4.916 20.069 1.00 0.00 N +ATOM 2260 HE2 HIS 241 23.946 4.066 20.107 1.00 0.00 H +ATOM 2261 C HIS 241 27.817 8.700 19.058 1.00 0.00 C +ATOM 2262 O HIS 241 28.377 9.801 19.045 1.00 0.00 O +ATOM 2263 N HIS 242 28.153 7.696 19.891 1.00 0.00 N +ATOM 2264 H HIS 242 27.674 6.841 19.825 1.00 0.00 H +ATOM 2265 CA HIS 242 29.207 7.715 20.943 1.00 0.00 C +ATOM 2266 CB HIS 242 30.590 7.323 20.366 1.00 0.00 C +ATOM 2267 CG HIS 242 30.685 5.894 19.914 1.00 0.00 C +ATOM 2268 CD2 HIS 242 31.455 4.868 20.354 1.00 0.00 C +ATOM 2269 ND1 HIS 242 29.937 5.386 18.872 1.00 0.00 N +ATOM 2270 HD1 HIS 242 29.280 5.886 18.343 1.00 0.00 H +ATOM 2271 CE1 HIS 242 30.240 4.113 18.691 1.00 0.00 C +ATOM 2272 NE2 HIS 242 31.158 3.775 19.577 1.00 0.00 N +ATOM 2273 HE2 HIS 242 31.563 2.887 19.667 1.00 0.00 H +ATOM 2274 C HIS 242 29.330 8.960 21.853 1.00 0.00 C +ATOM 2275 O HIS 242 29.098 8.858 23.064 1.00 0.00 O +ATOM 2276 N HIS 243 29.689 10.111 21.263 1.00 0.00 N +ATOM 2277 H HIS 243 29.876 10.135 20.300 1.00 0.00 H +ATOM 2278 CA HIS 243 29.852 11.392 21.975 1.00 0.00 C +ATOM 2279 CB HIS 243 31.238 12.003 21.658 1.00 0.00 C +ATOM 2280 CG HIS 243 31.779 12.911 22.728 1.00 0.00 C +ATOM 2281 CD2 HIS 243 32.847 12.781 23.553 1.00 0.00 C +ATOM 2282 ND1 HIS 243 31.212 14.132 23.031 1.00 0.00 N +ATOM 2283 HD1 HIS 243 30.418 14.515 22.602 1.00 0.00 H +ATOM 2284 CE1 HIS 243 31.905 14.714 23.993 1.00 0.00 C +ATOM 2285 NE2 HIS 243 32.902 13.914 24.327 1.00 0.00 N +ATOM 2286 HE2 HIS 243 33.574 14.100 25.017 1.00 0.00 H +ATOM 2287 C HIS 243 28.731 12.358 21.569 1.00 0.00 C +ATOM 2288 O HIS 243 28.269 12.271 20.411 1.00 0.00 O +ATOM 2289 OXT HIS 243 28.327 13.182 22.417 1.00 0.00 O +END diff --git a/examples/testdata/raptorxeg/models/195600_model_5.pdb b/examples/testdata/raptorxeg/models/195600_model_5.pdb new file mode 100644 index 0000000..7abd575 --- /dev/null +++ b/examples/testdata/raptorxeg/models/195600_model_5.pdb @@ -0,0 +1,2358 @@ +REMARK FILENAME="19_195600_3.pdb" +REMARK The macromolecule has 243 residues +REMARK Trial structure 3 of 10 structures +REMARK Molecular dynamics scheme : cartesian; cartesian; minimize +REMARK High temperature dynamics : +REMARK temp: 2000 steps: 1000 time(ps): 3 +REMARK 1st cooling stage : +REMARK temp: 2000->0 steps: 1000 time(ps): 5 temp step: 25 +REMARK 2nd cooling stage not used: +REMARK a total 36450 steps of minimization +REMARK VDW scale factors 20 20 0.01 0.003 0.003; 3E-03->4; 1 +REMARK 1073 NOEs in 3 class(es) with scale factors of 10; 10; 10 +REMARK averaging function(s): cent, sum, hbnd: cent +REMARK 0 3-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 1-bond j-couplings in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 carbon chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 proton chemical shifts in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 diffusion anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 0 susceptability anisotropy restraints in 0 class(es) with +REMARK scale factor(s) of NA +REMARK 188 dihedral restraints with scale factors of 5; 50; 50 +REMARK 0 planarity restraints with a scale factor of NA +REMARK NCS restraints not used. +REMARK =============================================================== +REMARK bond, angles, improp, vdw(<1.6), dihed +REMARK violations : 23 195 25 3 301 +REMARK RMSD : 0.0169 2.268 1.656 23.342 +REMARK =============================================================== +REMARK noe, cdih, coup, oneb, carb-a, carb-b, +REMARK violations : 115 8 0 0 0 ----- +REMARK RMSD : 0.547 2.059 0.000 0.000 0.000 0.000 +REMARK 0.2/2 viol.: 225 38 0 +REMARK =============================================================== +REMARK dani, sani +REMARK violations : 0 0 +REMARK RMSD : 0.000 0.000 +REMARK .2/.1 viol.: 0 0 +REMARK =============================================================== +REMARK Protons violations, rmsd +REMARK all : 0 0.000 +REMARK class 1: 0 0.000 +REMARK class 2: 0 0.000 +REMARK class 3: 0 0.000 +REMARK class 4: 0 0.000 +REMARK =============================================================== +REMARK overall = 12547.1 +REMARK bon = 822.038 +REMARK ang = 1307.42 +REMARK imp = 273.917 +REMARK vdw = 7829.61 +REMARK harm = 0 +REMARK noe = 1477.56 +REMARK coup = 0 +REMARK oneb = 0 +REMARK carb = 0 +REMARK prot = 0 +REMARK dani = 0 +REMARK sani = 0 +REMARK cdih = 60.7195 +REMARK ncs = 0 +REMARK =============================================================== +REMARK DATE:15-Jan-2017 12:28:59 created by user: RaptorX +REMARK VERSION:1.3 +ATOM 1 CB MET 1 17.122 16.709 7.850 1.00 0.00 C +ATOM 2 CG MET 1 16.283 17.655 8.720 1.00 0.00 C +ATOM 3 SD MET 1 14.527 17.755 8.280 1.00 0.00 S +ATOM 4 CE MET 1 14.456 19.371 7.503 1.00 0.00 C +ATOM 5 C MET 1 18.488 16.308 5.777 1.00 0.00 C +ATOM 6 O MET 1 19.687 16.598 5.879 1.00 0.00 O +ATOM 7 HT1 MET 1 15.472 17.840 6.062 1.00 0.00 H +ATOM 8 HT2 MET 1 16.395 17.601 4.658 1.00 0.00 H +ATOM 9 N MET 1 16.178 17.230 5.605 1.00 0.00 N +ATOM 10 HT3 MET 1 15.798 16.265 5.520 1.00 0.00 H +ATOM 11 CA MET 1 17.424 17.203 6.426 1.00 0.00 C +ATOM 12 N ALA 2 18.036 15.234 5.114 1.00 0.00 N +ATOM 13 H ALA 2 17.073 15.063 5.042 1.00 0.00 H +ATOM 14 CA ALA 2 18.904 14.261 4.429 1.00 0.00 C +ATOM 15 CB ALA 2 18.695 12.860 5.006 1.00 0.00 C +ATOM 16 C ALA 2 18.643 14.253 2.906 1.00 0.00 C +ATOM 17 O ALA 2 17.499 14.472 2.489 1.00 0.00 O +ATOM 18 N PRO 3 19.692 14.004 2.058 1.00 0.00 N +ATOM 19 CD PRO 3 21.124 13.907 2.424 1.00 0.00 C +ATOM 20 CA PRO 3 19.572 13.968 0.583 1.00 0.00 C +ATOM 21 CB PRO 3 21.011 13.722 0.139 1.00 0.00 C +ATOM 22 CG PRO 3 21.808 14.402 1.180 1.00 0.00 C +ATOM 23 C PRO 3 18.648 12.879 -0.001 1.00 0.00 C +ATOM 24 O PRO 3 18.248 12.963 -1.170 1.00 0.00 O +ATOM 25 N LYS 4 18.299 11.890 0.833 1.00 0.00 N +ATOM 26 H LYS 4 18.616 11.907 1.764 1.00 0.00 H +ATOM 27 CA LYS 4 17.445 10.745 0.457 1.00 0.00 C +ATOM 28 CB LYS 4 17.633 9.594 1.456 1.00 0.00 C +ATOM 29 CG LYS 4 19.022 8.955 1.429 1.00 0.00 C +ATOM 30 CD LYS 4 19.086 7.704 2.299 1.00 0.00 C +ATOM 31 CE LYS 4 20.469 7.058 2.280 1.00 0.00 C +ATOM 32 NZ LYS 4 20.826 6.449 0.963 1.00 0.00 N +ATOM 33 HZ1 LYS 4 21.776 6.029 1.022 1.00 0.00 H +ATOM 34 HZ2 LYS 4 20.816 7.183 0.227 1.00 0.00 H +ATOM 35 HZ3 LYS 4 20.134 5.709 0.725 1.00 0.00 H +ATOM 36 C LYS 4 15.948 11.079 0.274 1.00 0.00 C +ATOM 37 O LYS 4 15.305 11.610 1.191 1.00 0.00 O +ATOM 38 N LYS 5 15.430 10.784 -0.927 1.00 0.00 N +ATOM 39 H LYS 5 15.990 10.371 -1.621 1.00 0.00 H +ATOM 40 CA LYS 5 14.028 11.033 -1.322 1.00 0.00 C +ATOM 41 CB LYS 5 13.967 11.771 -2.667 1.00 0.00 C +ATOM 42 CG LYS 5 14.491 13.204 -2.640 1.00 0.00 C +ATOM 43 CD LYS 5 14.400 13.850 -4.013 1.00 0.00 C +ATOM 44 CE LYS 5 14.930 15.274 -3.990 1.00 0.00 C +ATOM 45 NZ LYS 5 14.847 15.920 -5.329 1.00 0.00 N +ATOM 46 HZ1 LYS 5 13.855 15.946 -5.640 1.00 0.00 H +ATOM 47 HZ2 LYS 5 15.410 15.374 -6.012 1.00 0.00 H +ATOM 48 HZ3 LYS 5 15.217 16.889 -5.270 1.00 0.00 H +ATOM 49 C LYS 5 13.186 9.752 -1.412 1.00 0.00 C +ATOM 50 O LYS 5 13.691 8.705 -1.832 1.00 0.00 O +ATOM 51 N VAL 6 11.913 9.851 -0.997 1.00 0.00 N +ATOM 52 H VAL 6 11.570 10.705 -0.652 1.00 0.00 H +ATOM 53 CA VAL 6 10.938 8.738 -1.012 1.00 0.00 C +ATOM 54 CB VAL 6 10.395 8.382 0.437 1.00 0.00 C +ATOM 55 CG1 VAL 6 9.851 6.945 0.484 1.00 0.00 C +ATOM 56 CG2 VAL 6 11.479 8.567 1.501 1.00 0.00 C +ATOM 57 C VAL 6 9.756 9.154 -1.921 1.00 0.00 C +ATOM 58 O VAL 6 9.389 10.336 -1.958 1.00 0.00 O +ATOM 59 N LEU 7 9.213 8.186 -2.673 1.00 0.00 N +ATOM 60 H LEU 7 9.571 7.272 -2.636 1.00 0.00 H +ATOM 61 CA LEU 7 8.072 8.389 -3.591 1.00 0.00 C +ATOM 62 CB LEU 7 8.468 8.038 -5.048 1.00 0.00 C +ATOM 63 CG LEU 7 9.558 8.821 -5.805 1.00 0.00 C +ATOM 64 CD1 LEU 7 10.526 7.842 -6.457 1.00 0.00 C +ATOM 65 CD2 LEU 7 8.955 9.757 -6.859 1.00 0.00 C +ATOM 66 C LEU 7 6.890 7.512 -3.135 1.00 0.00 C +ATOM 67 O LEU 7 7.070 6.308 -2.913 1.00 0.00 O +ATOM 68 N LEU 8 5.708 8.125 -2.962 1.00 0.00 N +ATOM 69 H LEU 8 5.618 9.088 -3.129 1.00 0.00 H +ATOM 70 CA LEU 8 4.483 7.420 -2.520 1.00 0.00 C +ATOM 71 CB LEU 8 4.073 7.821 -1.074 1.00 0.00 C +ATOM 72 CG LEU 8 4.025 9.245 -0.478 1.00 0.00 C +ATOM 73 CD1 LEU 8 2.744 9.413 0.322 1.00 0.00 C +ATOM 74 CD2 LEU 8 5.249 9.529 0.400 1.00 0.00 C +ATOM 75 C LEU 8 3.271 7.479 -3.469 1.00 0.00 C +ATOM 76 O LEU 8 2.984 8.531 -4.048 1.00 0.00 O +ATOM 77 N ALA 9 2.540 6.357 -3.552 1.00 0.00 N +ATOM 78 H ALA 9 2.789 5.564 -3.028 1.00 0.00 H +ATOM 79 CA ALA 9 1.339 6.194 -4.396 1.00 0.00 C +ATOM 80 CB ALA 9 1.444 4.908 -5.213 1.00 0.00 C +ATOM 81 C ALA 9 0.106 6.146 -3.481 1.00 0.00 C +ATOM 82 O ALA 9 0.099 5.393 -2.501 1.00 0.00 O +ATOM 83 N LEU 10 -0.921 6.943 -3.808 1.00 0.00 N +ATOM 84 H LEU 10 -0.883 7.497 -4.619 1.00 0.00 H +ATOM 85 CA LEU 10 -2.154 7.051 -3.004 1.00 0.00 C +ATOM 86 CB LEU 10 -2.376 8.515 -2.567 1.00 0.00 C +ATOM 87 CG LEU 10 -1.431 9.204 -1.564 1.00 0.00 C +ATOM 88 CD1 LEU 10 -0.713 10.384 -2.226 1.00 0.00 C +ATOM 89 CD2 LEU 10 -2.216 9.688 -0.345 1.00 0.00 C +ATOM 90 C LEU 10 -3.465 6.509 -3.590 1.00 0.00 C +ATOM 91 O LEU 10 -4.242 5.906 -2.850 1.00 0.00 O +ATOM 92 N THR 11 -3.679 6.707 -4.907 1.00 0.00 N +ATOM 93 H THR 11 -2.975 7.151 -5.428 1.00 0.00 H +ATOM 94 CA THR 11 -4.878 6.337 -5.736 1.00 0.00 C +ATOM 95 OG1 THR 11 -6.170 5.032 -4.060 1.00 0.00 O +ATOM 96 HG1 THR 11 -6.865 5.692 -4.065 1.00 0.00 H +ATOM 97 CG2 THR 11 -4.657 3.787 -5.472 1.00 0.00 C +ATOM 98 C THR 11 -5.912 7.483 -5.741 1.00 0.00 C +ATOM 99 O THR 11 -5.722 8.473 -5.027 1.00 0.00 O +ATOM 100 CB THR 11 -5.612 4.967 -5.375 1.00 0.00 C +ATOM 101 N SER 12 -6.967 7.356 -6.561 1.00 0.00 N +ATOM 102 H SER 12 -7.058 6.559 -7.126 1.00 0.00 H +ATOM 103 CA SER 12 -8.038 8.360 -6.682 1.00 0.00 C +ATOM 104 CB SER 12 -8.244 8.744 -8.152 1.00 0.00 C +ATOM 105 OG SER 12 -8.500 7.605 -8.955 1.00 0.00 O +ATOM 106 HG SER 12 -8.625 7.878 -9.867 1.00 0.00 H +ATOM 107 C SER 12 -9.371 7.919 -6.055 1.00 0.00 C +ATOM 108 O SER 12 -9.938 8.653 -5.237 1.00 0.00 O +ATOM 109 N TYR 13 -9.853 6.729 -6.443 1.00 0.00 N +ATOM 110 H TYR 13 -9.361 6.181 -7.093 1.00 0.00 H +ATOM 111 CA TYR 13 -11.118 6.158 -5.948 1.00 0.00 C +ATOM 112 CB TYR 13 -12.015 5.698 -7.120 1.00 0.00 C +ATOM 113 CG TYR 13 -12.382 6.741 -8.185 1.00 0.00 C +ATOM 114 CD1 TYR 13 -13.616 7.434 -8.133 1.00 0.00 C +ATOM 115 CE1 TYR 13 -13.982 8.369 -9.142 1.00 0.00 C +ATOM 116 CD2 TYR 13 -11.521 7.009 -9.279 1.00 0.00 C +ATOM 117 CE2 TYR 13 -11.879 7.941 -10.292 1.00 0.00 C +ATOM 118 CZ TYR 13 -13.109 8.614 -10.213 1.00 0.00 C +ATOM 119 OH TYR 13 -13.457 9.517 -11.192 1.00 0.00 O +ATOM 120 HH TYR 13 -14.320 9.895 -11.005 1.00 0.00 H +ATOM 121 C TYR 13 -10.884 4.974 -5.003 1.00 0.00 C +ATOM 122 O TYR 13 -9.927 4.210 -5.184 1.00 0.00 O +ATOM 123 N ASN 14 -11.760 4.850 -3.997 1.00 0.00 N +ATOM 124 H ASN 14 -12.494 5.495 -3.894 1.00 0.00 H +ATOM 125 CA ASN 14 -11.723 3.782 -2.979 1.00 0.00 C +ATOM 126 CB ASN 14 -11.006 4.252 -1.690 1.00 0.00 C +ATOM 127 CG ASN 14 -11.352 5.677 -1.289 1.00 0.00 C +ATOM 128 OD1 ASN 14 -10.683 6.620 -1.699 1.00 0.00 O +ATOM 129 ND2 ASN 14 -12.387 5.834 -0.469 1.00 0.00 N +ATOM 130 HD21 ASN 14 -12.619 6.748 -0.201 1.00 0.00 H +ATOM 131 HD22 ASN 14 -12.878 5.044 -0.165 1.00 0.00 H +ATOM 132 C ASN 14 -13.132 3.268 -2.653 1.00 0.00 C +ATOM 133 O ASN 14 -14.119 3.889 -3.055 1.00 0.00 O +ATOM 134 N ASP 15 -13.203 2.148 -1.909 1.00 0.00 N +ATOM 135 H ASP 15 -12.371 1.717 -1.612 1.00 0.00 H +ATOM 136 CA ASP 15 -14.438 1.453 -1.460 1.00 0.00 C +ATOM 137 CB ASP 15 -15.213 2.271 -0.399 1.00 0.00 C +ATOM 138 CG ASP 15 -14.386 2.559 0.849 1.00 0.00 C +ATOM 139 OD1 ASP 15 -13.785 3.652 0.928 1.00 0.00 O +ATOM 140 OD2 ASP 15 -14.345 1.700 1.756 1.00 0.00 O +ATOM 141 C ASP 15 -15.384 0.984 -2.579 1.00 0.00 C +ATOM 142 O ASP 15 -15.659 -0.217 -2.683 1.00 0.00 O +ATOM 143 N VAL 16 -15.843 1.936 -3.417 1.00 0.00 N +ATOM 144 H VAL 16 -15.591 2.868 -3.274 1.00 0.00 H +ATOM 145 CA VAL 16 -16.765 1.755 -4.575 1.00 0.00 C +ATOM 146 CB VAL 16 -16.001 1.787 -5.979 1.00 0.00 C +ATOM 147 CG1 VAL 16 -15.477 3.189 -6.257 1.00 0.00 C +ATOM 148 CG2 VAL 16 -14.847 0.766 -6.037 1.00 0.00 C +ATOM 149 C VAL 16 -17.831 0.622 -4.480 1.00 0.00 C +ATOM 150 O VAL 16 -18.275 0.060 -5.495 1.00 0.00 O +ATOM 151 N PHE 17 -18.246 0.343 -3.236 1.00 0.00 N +ATOM 152 H PHE 17 -17.879 0.844 -2.473 1.00 0.00 H +ATOM 153 CA PHE 17 -19.244 -0.681 -2.882 1.00 0.00 C +ATOM 154 CB PHE 17 -18.877 -1.305 -1.505 1.00 0.00 C +ATOM 155 CG PHE 17 -19.153 -2.804 -1.382 1.00 0.00 C +ATOM 156 CD1 PHE 17 -20.426 -3.283 -0.987 1.00 0.00 C +ATOM 157 CD2 PHE 17 -18.120 -3.745 -1.608 1.00 0.00 C +ATOM 158 CE1 PHE 17 -20.667 -4.674 -0.817 1.00 0.00 C +ATOM 159 CE2 PHE 17 -18.346 -5.139 -1.441 1.00 0.00 C +ATOM 160 CZ PHE 17 -19.623 -5.604 -1.045 1.00 0.00 C +ATOM 161 C PHE 17 -20.631 -0.002 -2.831 1.00 0.00 C +ATOM 162 O PHE 17 -20.787 1.036 -2.172 1.00 0.00 O +ATOM 163 N TYR 18 -21.610 -0.575 -3.546 1.00 0.00 N +ATOM 164 H TYR 18 -21.439 -1.399 -4.052 1.00 0.00 H +ATOM 165 CA TYR 18 -22.981 -0.034 -3.628 1.00 0.00 C +ATOM 166 CB TYR 18 -23.606 -0.323 -5.026 1.00 0.00 C +ATOM 167 CG TYR 18 -23.573 -1.770 -5.545 1.00 0.00 C +ATOM 168 CD1 TYR 18 -22.478 -2.250 -6.307 1.00 0.00 C +ATOM 169 CE1 TYR 18 -22.466 -3.573 -6.831 1.00 0.00 C +ATOM 170 CD2 TYR 18 -24.658 -2.652 -5.320 1.00 0.00 C +ATOM 171 CE2 TYR 18 -24.655 -3.976 -5.841 1.00 0.00 C +ATOM 172 CZ TYR 18 -23.557 -4.424 -6.593 1.00 0.00 C +ATOM 173 OH TYR 18 -23.550 -5.702 -7.104 1.00 0.00 O +ATOM 174 HH TYR 18 -24.358 -6.162 -6.863 1.00 0.00 H +ATOM 175 C TYR 18 -23.955 -0.386 -2.478 1.00 0.00 C +ATOM 176 O TYR 18 -24.490 -1.503 -2.414 1.00 0.00 O +ATOM 177 N SER 19 -24.112 0.572 -1.552 1.00 0.00 N +ATOM 178 H SER 19 -23.615 1.416 -1.626 1.00 0.00 H +ATOM 179 CA SER 19 -24.998 0.487 -0.373 1.00 0.00 C +ATOM 180 CB SER 19 -24.275 -0.138 0.835 1.00 0.00 C +ATOM 181 OG SER 19 -23.840 -1.454 0.541 1.00 0.00 O +ATOM 182 HG SER 19 -23.391 -1.817 1.307 1.00 0.00 H +ATOM 183 C SER 19 -25.457 1.910 -0.020 1.00 0.00 C +ATOM 184 O SER 19 -26.643 2.129 0.255 1.00 0.00 O +ATOM 185 N ASP 20 -24.505 2.857 -0.033 1.00 0.00 N +ATOM 186 H ASP 20 -23.577 2.621 -0.254 1.00 0.00 H +ATOM 187 CA ASP 20 -24.733 4.285 0.269 1.00 0.00 C +ATOM 188 CB ASP 20 -24.183 4.668 1.670 1.00 0.00 C +ATOM 189 CG ASP 20 -22.767 4.136 1.937 1.00 0.00 C +ATOM 190 OD1 ASP 20 -22.640 3.010 2.467 1.00 0.00 O +ATOM 191 OD2 ASP 20 -21.789 4.852 1.629 1.00 0.00 O +ATOM 192 C ASP 20 -24.141 5.198 -0.817 1.00 0.00 C +ATOM 193 O ASP 20 -24.745 6.218 -1.170 1.00 0.00 O +ATOM 194 N GLY 21 -22.967 4.816 -1.330 1.00 0.00 N +ATOM 195 H GLY 21 -22.520 3.996 -1.023 1.00 0.00 H +ATOM 196 CA GLY 21 -22.282 5.579 -2.366 1.00 0.00 C +ATOM 197 C GLY 21 -21.028 4.878 -2.860 1.00 0.00 C +ATOM 198 O GLY 21 -20.948 3.645 -2.796 1.00 0.00 O +ATOM 199 N ALA 22 -20.061 5.663 -3.349 1.00 0.00 N +ATOM 200 H ALA 22 -20.203 6.634 -3.368 1.00 0.00 H +ATOM 201 CA ALA 22 -18.779 5.159 -3.870 1.00 0.00 C +ATOM 202 CB ALA 22 -18.546 5.664 -5.291 1.00 0.00 C +ATOM 203 C ALA 22 -17.603 5.561 -2.974 1.00 0.00 C +ATOM 204 O ALA 22 -16.606 4.833 -2.907 1.00 0.00 O +ATOM 205 N LYS 23 -17.753 6.698 -2.269 1.00 0.00 N +ATOM 206 H LYS 23 -18.590 7.205 -2.349 1.00 0.00 H +ATOM 207 CA LYS 23 -16.763 7.314 -1.337 1.00 0.00 C +ATOM 208 CB LYS 23 -17.003 6.896 0.143 1.00 0.00 C +ATOM 209 CG LYS 23 -17.120 5.394 0.466 1.00 0.00 C +ATOM 210 CD LYS 23 -17.385 5.168 1.951 1.00 0.00 C +ATOM 211 CE LYS 23 -17.566 3.690 2.289 1.00 0.00 C +ATOM 212 NZ LYS 23 -18.820 3.099 1.733 1.00 0.00 N +ATOM 213 HZ1 LYS 23 -18.812 3.182 0.696 1.00 0.00 H +ATOM 214 HZ2 LYS 23 -19.642 3.608 2.115 1.00 0.00 H +ATOM 215 HZ3 LYS 23 -18.878 2.096 2.000 1.00 0.00 H +ATOM 216 C LYS 23 -15.258 7.281 -1.705 1.00 0.00 C +ATOM 217 O LYS 23 -14.661 6.200 -1.791 1.00 0.00 O +ATOM 218 N THR 24 -14.678 8.469 -1.938 1.00 0.00 N +ATOM 219 H THR 24 -15.199 9.299 -1.864 1.00 0.00 H +ATOM 220 CA THR 24 -13.257 8.632 -2.311 1.00 0.00 C +ATOM 221 CB THR 24 -13.087 9.397 -3.663 1.00 0.00 C +ATOM 222 OG1 THR 24 -13.687 10.696 -3.566 1.00 0.00 O +ATOM 223 HG1 THR 24 -13.238 11.226 -2.902 1.00 0.00 H +ATOM 224 CG2 THR 24 -13.748 8.634 -4.800 1.00 0.00 C +ATOM 225 C THR 24 -12.414 9.320 -1.223 1.00 0.00 C +ATOM 226 O THR 24 -12.945 10.092 -0.417 1.00 0.00 O +ATOM 227 N GLY 25 -11.110 9.015 -1.207 1.00 0.00 N +ATOM 228 H GLY 25 -10.723 8.427 -1.887 1.00 0.00 H +ATOM 229 CA GLY 25 -10.168 9.580 -0.246 1.00 0.00 C +ATOM 230 C GLY 25 -10.142 8.935 1.135 1.00 0.00 C +ATOM 231 O GLY 25 -10.963 9.279 1.993 1.00 0.00 O +ATOM 232 N VAL 26 -9.203 7.999 1.330 1.00 0.00 N +ATOM 233 H VAL 26 -8.592 7.790 0.591 1.00 0.00 H +ATOM 234 CA VAL 26 -9.007 7.240 2.586 1.00 0.00 C +ATOM 235 CB VAL 26 -9.564 5.770 2.469 1.00 0.00 C +ATOM 236 CG1 VAL 26 -11.088 5.774 2.431 1.00 0.00 C +ATOM 237 CG2 VAL 26 -8.991 5.034 1.245 1.00 0.00 C +ATOM 238 C VAL 26 -7.507 7.169 2.948 1.00 0.00 C +ATOM 239 O VAL 26 -7.126 7.140 4.125 1.00 0.00 O +ATOM 240 N PHE 27 -6.695 7.186 1.887 1.00 0.00 N +ATOM 241 H PHE 27 -7.150 7.279 1.031 1.00 0.00 H +ATOM 242 CA PHE 27 -5.223 7.108 1.858 1.00 0.00 C +ATOM 243 CG PHE 27 -5.743 7.394 -0.674 1.00 0.00 C +ATOM 244 CD1 PHE 27 -5.760 8.689 -1.229 1.00 0.00 C +ATOM 245 CD2 PHE 27 -6.706 6.458 -1.124 1.00 0.00 C +ATOM 246 CE1 PHE 27 -6.718 9.052 -2.213 1.00 0.00 C +ATOM 247 CE2 PHE 27 -7.668 6.808 -2.105 1.00 0.00 C +ATOM 248 CZ PHE 27 -7.675 8.109 -2.650 1.00 0.00 C +ATOM 249 C PHE 27 -4.453 8.181 2.640 1.00 0.00 C +ATOM 250 O PHE 27 -3.329 7.922 3.085 1.00 0.00 O +ATOM 251 CB PHE 27 -4.713 7.010 0.393 1.00 0.00 C +ATOM 252 N VAL 28 -5.060 9.368 2.795 1.00 0.00 N +ATOM 253 H VAL 28 -5.967 9.478 2.429 1.00 0.00 H +ATOM 254 CA VAL 28 -4.458 10.532 3.487 1.00 0.00 C +ATOM 255 CB VAL 28 -5.444 11.783 3.457 1.00 0.00 C +ATOM 256 CG1 VAL 28 -6.717 11.545 4.296 1.00 0.00 C +ATOM 257 CG2 VAL 28 -4.728 13.088 3.840 1.00 0.00 C +ATOM 258 C VAL 28 -3.947 10.233 4.925 1.00 0.00 C +ATOM 259 O VAL 28 -2.835 10.640 5.258 1.00 0.00 O +ATOM 260 N VAL 29 -4.725 9.491 5.728 1.00 0.00 N +ATOM 261 H VAL 29 -5.591 9.172 5.387 1.00 0.00 H +ATOM 262 CA VAL 29 -4.347 9.116 7.112 1.00 0.00 C +ATOM 263 CB VAL 29 -5.570 8.571 7.946 1.00 0.00 C +ATOM 264 CG1 VAL 29 -6.498 9.718 8.311 1.00 0.00 C +ATOM 265 CG2 VAL 29 -6.358 7.485 7.180 1.00 0.00 C +ATOM 266 C VAL 29 -3.159 8.126 7.148 1.00 0.00 C +ATOM 267 O VAL 29 -2.234 8.279 7.960 1.00 0.00 O +ATOM 268 N GLU 30 -3.181 7.167 6.208 1.00 0.00 N +ATOM 269 H GLU 30 -3.931 7.142 5.572 1.00 0.00 H +ATOM 270 CA GLU 30 -2.151 6.125 6.039 1.00 0.00 C +ATOM 271 CB GLU 30 -2.641 5.077 5.014 1.00 0.00 C +ATOM 272 CG GLU 30 -1.907 3.736 4.997 1.00 0.00 C +ATOM 273 CD GLU 30 -2.485 2.777 3.976 1.00 0.00 C +ATOM 274 OE1 GLU 30 -1.914 2.673 2.874 1.00 0.00 O +ATOM 275 OE2 GLU 30 -3.507 2.124 4.271 1.00 0.00 O +ATOM 276 C GLU 30 -0.855 6.814 5.567 1.00 0.00 C +ATOM 277 O GLU 30 0.215 6.528 6.096 1.00 0.00 O +ATOM 278 N ALA 31 -0.987 7.745 4.613 1.00 0.00 N +ATOM 279 H ALA 31 -1.875 7.957 4.264 1.00 0.00 H +ATOM 280 CA ALA 31 0.127 8.523 4.042 1.00 0.00 C +ATOM 281 CB ALA 31 -0.324 9.228 2.776 1.00 0.00 C +ATOM 282 C ALA 31 0.729 9.531 5.034 1.00 0.00 C +ATOM 283 O ALA 31 1.952 9.694 5.072 1.00 0.00 O +ATOM 284 N LEU 32 -0.133 10.153 5.857 1.00 0.00 N +ATOM 285 H LEU 32 -1.089 9.942 5.806 1.00 0.00 H +ATOM 286 CA LEU 32 0.259 11.148 6.880 1.00 0.00 C +ATOM 287 CB LEU 32 -0.964 11.902 7.443 1.00 0.00 C +ATOM 288 CG LEU 32 -1.512 13.187 6.790 1.00 0.00 C +ATOM 289 CD1 LEU 32 -3.005 13.266 7.060 1.00 0.00 C +ATOM 290 CD2 LEU 32 -0.814 14.466 7.294 1.00 0.00 C +ATOM 291 C LEU 32 1.083 10.557 8.030 1.00 0.00 C +ATOM 292 O LEU 32 2.015 11.216 8.508 1.00 0.00 O +ATOM 293 N HIS 33 0.759 9.320 8.449 1.00 0.00 N +ATOM 294 H HIS 33 -0.007 8.844 8.048 1.00 0.00 H +ATOM 295 CA HIS 33 1.491 8.626 9.529 1.00 0.00 C +ATOM 296 CB HIS 33 0.737 7.364 10.004 1.00 0.00 C +ATOM 297 CG HIS 33 -0.446 7.648 10.885 1.00 0.00 C +ATOM 298 CD2 HIS 33 -0.761 7.194 12.122 1.00 0.00 C +ATOM 299 ND1 HIS 33 -1.481 8.479 10.511 1.00 0.00 N +ATOM 300 HD1 HIS 33 -1.536 8.980 9.672 1.00 0.00 H +ATOM 301 CE1 HIS 33 -2.381 8.526 11.477 1.00 0.00 C +ATOM 302 NE2 HIS 33 -1.968 7.755 12.466 1.00 0.00 N +ATOM 303 HE2 HIS 33 -2.445 7.606 13.309 1.00 0.00 H +ATOM 304 C HIS 33 2.943 8.315 9.062 1.00 0.00 C +ATOM 305 O HIS 33 3.882 8.631 9.804 1.00 0.00 O +ATOM 306 N PRO 34 3.157 7.722 7.834 1.00 0.00 N +ATOM 307 CD PRO 34 2.276 6.893 6.987 1.00 0.00 C +ATOM 308 CA PRO 34 4.542 7.467 7.401 1.00 0.00 C +ATOM 309 CB PRO 34 4.363 6.628 6.140 1.00 0.00 C +ATOM 310 CG PRO 34 3.214 5.821 6.470 1.00 0.00 C +ATOM 311 C PRO 34 5.281 8.784 7.107 1.00 0.00 C +ATOM 312 O PRO 34 6.477 8.888 7.371 1.00 0.00 O +ATOM 313 N PHE 35 4.539 9.777 6.586 1.00 0.00 N +ATOM 314 H PHE 35 3.583 9.616 6.417 1.00 0.00 H +ATOM 315 CA PHE 35 5.045 11.122 6.233 1.00 0.00 C +ATOM 316 CB PHE 35 3.900 11.970 5.610 1.00 0.00 C +ATOM 317 CG PHE 35 4.316 12.871 4.446 1.00 0.00 C +ATOM 318 CD1 PHE 35 4.712 14.211 4.673 1.00 0.00 C +ATOM 319 CD2 PHE 35 4.261 12.402 3.111 1.00 0.00 C +ATOM 320 CE1 PHE 35 5.047 15.073 3.592 1.00 0.00 C +ATOM 321 CE2 PHE 35 4.593 13.252 2.019 1.00 0.00 C +ATOM 322 CZ PHE 35 4.987 14.591 2.261 1.00 0.00 C +ATOM 323 C PHE 35 5.633 11.861 7.455 1.00 0.00 C +ATOM 324 O PHE 35 6.750 12.379 7.371 1.00 0.00 O +ATOM 325 N ASN 36 4.910 11.846 8.589 1.00 0.00 N +ATOM 326 H ASN 36 4.045 11.384 8.621 1.00 0.00 H +ATOM 327 CA ASN 36 5.355 12.506 9.833 1.00 0.00 C +ATOM 328 CB ASN 36 4.196 12.716 10.844 1.00 0.00 C +ATOM 329 CG ASN 36 3.473 11.418 11.246 1.00 0.00 C +ATOM 330 OD1 ASN 36 4.085 10.460 11.729 1.00 0.00 O +ATOM 331 ND2 ASN 36 2.152 11.422 11.106 1.00 0.00 N +ATOM 332 HD21 ASN 36 1.669 10.607 11.356 1.00 0.00 H +ATOM 333 HD22 ASN 36 1.707 12.225 10.764 1.00 0.00 H +ATOM 334 C ASN 36 6.577 11.848 10.501 1.00 0.00 C +ATOM 335 O ASN 36 7.516 12.552 10.889 1.00 0.00 O +ATOM 336 N THR 37 6.573 10.508 10.585 1.00 0.00 N +ATOM 337 H THR 37 5.800 9.996 10.236 1.00 0.00 H +ATOM 338 CA THR 37 7.682 9.740 11.190 1.00 0.00 C +ATOM 339 CB THR 37 7.269 8.257 11.550 1.00 0.00 C +ATOM 340 OG1 THR 37 8.376 7.573 12.154 1.00 0.00 O +ATOM 341 HG1 THR 37 8.622 7.999 12.979 1.00 0.00 H +ATOM 342 CG2 THR 37 6.786 7.474 10.334 1.00 0.00 C +ATOM 343 C THR 37 8.985 9.819 10.351 1.00 0.00 C +ATOM 344 O THR 37 10.079 9.908 10.919 1.00 0.00 O +ATOM 345 N PHE 38 8.842 9.793 9.015 1.00 0.00 N +ATOM 346 H PHE 38 7.945 9.699 8.625 1.00 0.00 H +ATOM 347 CA PHE 38 9.963 9.897 8.055 1.00 0.00 C +ATOM 348 CB PHE 38 9.526 9.466 6.633 1.00 0.00 C +ATOM 349 CG PHE 38 9.783 7.997 6.306 1.00 0.00 C +ATOM 350 CD1 PHE 38 10.975 7.604 5.651 1.00 0.00 C +ATOM 351 CD2 PHE 38 8.824 7.002 6.613 1.00 0.00 C +ATOM 352 CE1 PHE 38 11.211 6.245 5.307 1.00 0.00 C +ATOM 353 CE2 PHE 38 9.046 5.641 6.275 1.00 0.00 C +ATOM 354 CZ PHE 38 10.244 5.261 5.620 1.00 0.00 C +ATOM 355 C PHE 38 10.603 11.298 8.016 1.00 0.00 C +ATOM 356 O PHE 38 11.827 11.412 7.889 1.00 0.00 O +ATOM 357 N ARG 39 9.766 12.343 8.124 1.00 0.00 N +ATOM 358 H ARG 39 8.795 12.184 8.195 1.00 0.00 H +ATOM 359 CA ARG 39 10.193 13.762 8.134 1.00 0.00 C +ATOM 360 CB ARG 39 8.994 14.706 7.987 1.00 0.00 C +ATOM 361 CG ARG 39 8.495 14.883 6.556 1.00 0.00 C +ATOM 362 CD ARG 39 7.412 15.958 6.456 1.00 0.00 C +ATOM 363 NE ARG 39 6.167 15.586 7.136 1.00 0.00 N +ATOM 364 HE ARG 39 6.060 14.651 7.408 1.00 0.00 H +ATOM 365 CZ ARG 39 5.165 16.421 7.417 1.00 0.00 C +ATOM 366 NH1 ARG 39 4.087 15.963 8.038 1.00 0.00 N +ATOM 367 HH11 ARG 39 4.029 14.998 8.293 1.00 0.00 H +ATOM 368 HH12 ARG 39 3.332 16.583 8.252 1.00 0.00 H +ATOM 369 NH2 ARG 39 5.227 17.707 7.085 1.00 0.00 N +ATOM 370 HH21 ARG 39 6.035 18.064 6.616 1.00 0.00 H +ATOM 371 HH22 ARG 39 4.466 18.318 7.304 1.00 0.00 H +ATOM 372 C ARG 39 10.979 14.123 9.405 1.00 0.00 C +ATOM 373 O ARG 39 11.925 14.918 9.347 1.00 0.00 O +ATOM 374 N LYS 40 10.571 13.529 10.536 1.00 0.00 N +ATOM 375 H LYS 40 9.788 12.925 10.513 1.00 0.00 H +ATOM 376 CA LYS 40 11.192 13.725 11.863 1.00 0.00 C +ATOM 377 CB LYS 40 10.313 13.129 12.971 1.00 0.00 C +ATOM 378 CG LYS 40 9.078 13.954 13.309 1.00 0.00 C +ATOM 379 CD LYS 40 8.259 13.297 14.415 1.00 0.00 C +ATOM 380 CE LYS 40 7.015 14.107 14.771 1.00 0.00 C +ATOM 381 NZ LYS 40 7.320 15.407 15.443 1.00 0.00 N +ATOM 382 HZ1 LYS 40 7.837 15.227 16.327 1.00 0.00 H +ATOM 383 HZ2 LYS 40 7.903 15.994 14.813 1.00 0.00 H +ATOM 384 HZ3 LYS 40 6.432 15.904 15.655 1.00 0.00 H +ATOM 385 C LYS 40 12.620 13.158 11.971 1.00 0.00 C +ATOM 386 O LYS 40 13.467 13.751 12.648 1.00 0.00 O +ATOM 387 N GLU 41 12.869 12.025 11.295 1.00 0.00 N +ATOM 388 H GLU 41 12.154 11.613 10.761 1.00 0.00 H +ATOM 389 CA GLU 41 14.175 11.327 11.284 1.00 0.00 C +ATOM 390 CB GLU 41 14.011 9.878 10.803 1.00 0.00 C +ATOM 391 CG GLU 41 13.328 8.959 11.812 1.00 0.00 C +ATOM 392 CD GLU 41 13.187 7.535 11.313 1.00 0.00 C +ATOM 393 OE1 GLU 41 14.173 6.772 11.395 1.00 0.00 O +ATOM 394 OE2 GLU 41 12.086 7.178 10.845 1.00 0.00 O +ATOM 395 C GLU 41 15.300 12.019 10.492 1.00 0.00 C +ATOM 396 O GLU 41 16.420 12.140 11.000 1.00 0.00 O +ATOM 397 N GLY 42 14.997 12.461 9.266 1.00 0.00 N +ATOM 398 H GLY 42 14.098 12.345 8.890 1.00 0.00 H +ATOM 399 CA GLY 42 15.990 13.135 8.438 1.00 0.00 C +ATOM 400 C GLY 42 15.721 13.113 6.945 1.00 0.00 C +ATOM 401 O GLY 42 15.873 14.145 6.283 1.00 0.00 O +ATOM 402 N PHE 43 15.302 11.952 6.425 1.00 0.00 N +ATOM 403 H PHE 43 15.173 11.188 7.027 1.00 0.00 H +ATOM 404 CA PHE 43 15.017 11.742 4.991 1.00 0.00 C +ATOM 405 CB PHE 43 14.987 10.225 4.647 1.00 0.00 C +ATOM 406 CG PHE 43 15.974 9.364 5.442 1.00 0.00 C +ATOM 407 CD1 PHE 43 17.339 9.282 5.075 1.00 0.00 C +ATOM 408 CD2 PHE 43 15.529 8.604 6.549 1.00 0.00 C +ATOM 409 CE1 PHE 43 18.247 8.460 5.798 1.00 0.00 C +ATOM 410 CE2 PHE 43 16.425 7.777 7.283 1.00 0.00 C +ATOM 411 CZ PHE 43 17.787 7.706 6.905 1.00 0.00 C +ATOM 412 C PHE 43 13.705 12.410 4.533 1.00 0.00 C +ATOM 413 O PHE 43 12.718 12.413 5.280 1.00 0.00 O +ATOM 414 N GLU 44 13.721 12.975 3.318 1.00 0.00 N +ATOM 415 H GLU 44 14.534 12.939 2.767 1.00 0.00 H +ATOM 416 CA GLU 44 12.570 13.676 2.712 1.00 0.00 C +ATOM 417 CB GLU 44 13.041 14.877 1.858 1.00 0.00 C +ATOM 418 CG GLU 44 14.193 14.630 0.861 1.00 0.00 C +ATOM 419 CD GLU 44 14.576 15.879 0.090 1.00 0.00 C +ATOM 420 OE1 GLU 44 13.992 16.117 -0.988 1.00 0.00 O +ATOM 421 OE2 GLU 44 15.463 16.621 0.562 1.00 0.00 O +ATOM 422 C GLU 44 11.587 12.781 1.926 1.00 0.00 C +ATOM 423 O GLU 44 12.014 11.869 1.208 1.00 0.00 O +ATOM 424 N VAL 45 10.284 13.054 2.091 1.00 0.00 N +ATOM 425 H VAL 45 10.002 13.787 2.681 1.00 0.00 H +ATOM 426 CA VAL 45 9.185 12.315 1.433 1.00 0.00 C +ATOM 427 CG1 VAL 45 8.718 10.471 3.115 1.00 0.00 C +ATOM 428 CG2 VAL 45 7.813 12.746 3.580 1.00 0.00 C +ATOM 429 C VAL 45 8.455 13.142 0.350 1.00 0.00 C +ATOM 430 O VAL 45 8.217 14.344 0.535 1.00 0.00 O +ATOM 431 CB VAL 45 8.151 11.725 2.474 1.00 0.00 C +ATOM 432 N ASP 46 8.141 12.486 -0.775 1.00 0.00 N +ATOM 433 H ASP 46 8.357 11.535 -0.861 1.00 0.00 H +ATOM 434 CA ASP 46 7.446 13.084 -1.933 1.00 0.00 C +ATOM 435 CB ASP 46 8.395 13.206 -3.144 1.00 0.00 C +ATOM 436 CG ASP 46 9.573 14.141 -2.884 1.00 0.00 C +ATOM 437 OD1 ASP 46 10.637 13.656 -2.442 1.00 0.00 O +ATOM 438 OD2 ASP 46 9.440 15.360 -3.135 1.00 0.00 O +ATOM 439 C ASP 46 6.231 12.225 -2.313 1.00 0.00 C +ATOM 440 O ASP 46 6.296 10.994 -2.213 1.00 0.00 O +ATOM 441 N PHE 47 5.139 12.877 -2.741 1.00 0.00 N +ATOM 442 H PHE 47 5.136 13.857 -2.802 1.00 0.00 H +ATOM 443 CA PHE 47 3.892 12.196 -3.143 1.00 0.00 C +ATOM 444 CB PHE 47 2.653 12.770 -2.383 1.00 0.00 C +ATOM 445 CG PHE 47 2.564 14.304 -2.340 1.00 0.00 C +ATOM 446 CD1 PHE 47 3.151 15.034 -1.279 1.00 0.00 C +ATOM 447 CD2 PHE 47 1.861 15.017 -3.341 1.00 0.00 C +ATOM 448 CE1 PHE 47 3.040 16.451 -1.212 1.00 0.00 C +ATOM 449 CE2 PHE 47 1.742 16.433 -3.288 1.00 0.00 C +ATOM 450 CZ PHE 47 2.334 17.151 -2.220 1.00 0.00 C +ATOM 451 C PHE 47 3.651 12.229 -4.661 1.00 0.00 C +ATOM 452 O PHE 47 3.694 13.301 -5.279 1.00 0.00 O +ATOM 453 N VAL 48 3.424 11.044 -5.242 1.00 0.00 N +ATOM 454 H VAL 48 3.431 10.224 -4.711 1.00 0.00 H +ATOM 455 CA VAL 48 3.167 10.878 -6.683 1.00 0.00 C +ATOM 456 CB VAL 48 4.262 10.008 -7.414 1.00 0.00 C +ATOM 457 CG1 VAL 48 5.529 10.821 -7.592 1.00 0.00 C +ATOM 458 CG2 VAL 48 4.585 8.707 -6.650 1.00 0.00 C +ATOM 459 C VAL 48 1.760 10.363 -7.022 1.00 0.00 C +ATOM 460 O VAL 48 1.215 9.496 -6.325 1.00 0.00 O +ATOM 461 N SER 49 1.191 10.936 -8.088 1.00 0.00 N +ATOM 462 H SER 49 1.664 11.639 -8.586 1.00 0.00 H +ATOM 463 CA SER 49 -0.138 10.610 -8.621 1.00 0.00 C +ATOM 464 CB SER 49 -1.017 11.866 -8.586 1.00 0.00 C +ATOM 465 OG SER 49 -0.274 13.003 -8.990 1.00 0.00 O +ATOM 466 HG SER 49 -0.769 13.795 -8.777 1.00 0.00 H +ATOM 467 C SER 49 0.090 10.109 -10.060 1.00 0.00 C +ATOM 468 O SER 49 0.568 10.872 -10.911 1.00 0.00 O +ATOM 469 N GLU 50 -0.217 8.823 -10.303 1.00 0.00 N +ATOM 470 H GLU 50 -0.598 8.279 -9.578 1.00 0.00 H +ATOM 471 CA GLU 50 -0.028 8.122 -11.600 1.00 0.00 C +ATOM 472 CB GLU 50 -0.724 6.741 -11.589 1.00 0.00 C +ATOM 473 CG GLU 50 -2.255 6.726 -11.423 1.00 0.00 C +ATOM 474 CD GLU 50 -2.882 5.390 -11.791 1.00 0.00 C +ATOM 475 OE1 GLU 50 -3.457 4.737 -10.896 1.00 0.00 O +ATOM 476 OE2 GLU 50 -2.815 4.998 -12.977 1.00 0.00 O +ATOM 477 C GLU 50 -0.305 8.879 -12.923 1.00 0.00 C +ATOM 478 O GLU 50 0.365 8.630 -13.934 1.00 0.00 O +ATOM 479 N THR 51 -1.279 9.800 -12.886 1.00 0.00 N +ATOM 480 H THR 51 -1.779 9.958 -12.055 1.00 0.00 H +ATOM 481 CA THR 51 -1.681 10.631 -14.038 1.00 0.00 C +ATOM 482 CB THR 51 -3.211 10.497 -14.343 1.00 0.00 C +ATOM 483 OG1 THR 51 -3.968 10.721 -13.147 1.00 0.00 O +ATOM 484 HG1 THR 51 -3.766 10.049 -12.490 1.00 0.00 H +ATOM 485 CG2 THR 51 -3.533 9.115 -14.902 1.00 0.00 C +ATOM 486 C THR 51 -1.337 12.107 -13.769 1.00 0.00 C +ATOM 487 O THR 51 -1.072 12.875 -14.704 1.00 0.00 O +ATOM 488 N GLY 52 -1.306 12.466 -12.481 1.00 0.00 N +ATOM 489 H GLY 52 -1.482 11.814 -11.767 1.00 0.00 H +ATOM 490 CA GLY 52 -1.012 13.825 -12.046 1.00 0.00 C +ATOM 491 C GLY 52 -2.131 14.297 -11.131 1.00 0.00 C +ATOM 492 O GLY 52 -1.875 14.755 -10.013 1.00 0.00 O +ATOM 493 N LYS 53 -3.371 14.180 -11.618 1.00 0.00 N +ATOM 494 H LYS 53 -3.494 13.825 -12.525 1.00 0.00 H +ATOM 495 CA LYS 53 -4.585 14.553 -10.875 1.00 0.00 C +ATOM 496 CB LYS 53 -5.538 15.414 -11.749 1.00 0.00 C +ATOM 497 CG LYS 53 -5.823 14.916 -13.182 1.00 0.00 C +ATOM 498 CD LYS 53 -6.771 15.859 -13.917 1.00 0.00 C +ATOM 499 CE LYS 53 -7.068 15.386 -15.339 1.00 0.00 C +ATOM 500 NZ LYS 53 -5.891 15.472 -16.255 1.00 0.00 N +ATOM 501 HZ1 LYS 53 -6.163 15.136 -17.201 1.00 0.00 H +ATOM 502 HZ2 LYS 53 -5.571 16.460 -16.316 1.00 0.00 H +ATOM 503 HZ3 LYS 53 -5.120 14.880 -15.885 1.00 0.00 H +ATOM 504 C LYS 53 -5.252 13.265 -10.326 1.00 0.00 C +ATOM 505 O LYS 53 -6.436 12.993 -10.580 1.00 0.00 O +ATOM 506 N PHE 54 -4.452 12.482 -9.588 1.00 0.00 N +ATOM 507 H PHE 54 -3.523 12.745 -9.407 1.00 0.00 H +ATOM 508 CA PHE 54 -4.867 11.201 -8.996 1.00 0.00 C +ATOM 509 CB PHE 54 -4.039 10.049 -9.619 1.00 0.00 C +ATOM 510 CG PHE 54 -4.855 8.822 -10.032 1.00 0.00 C +ATOM 511 CD1 PHE 54 -4.934 7.695 -9.185 1.00 0.00 C +ATOM 512 CD2 PHE 54 -5.503 8.766 -11.290 1.00 0.00 C +ATOM 513 CE1 PHE 54 -5.645 6.527 -9.578 1.00 0.00 C +ATOM 514 CE2 PHE 54 -6.218 7.606 -11.698 1.00 0.00 C +ATOM 515 CZ PHE 54 -6.288 6.483 -10.839 1.00 0.00 C +ATOM 516 C PHE 54 -4.743 11.161 -7.467 1.00 0.00 C +ATOM 517 O PHE 54 -5.439 10.377 -6.817 1.00 0.00 O +ATOM 518 N GLY 55 -3.878 12.013 -6.901 1.00 0.00 N +ATOM 519 H GLY 55 -3.356 12.638 -7.450 1.00 0.00 H +ATOM 520 CA GLY 55 -3.662 12.066 -5.453 1.00 0.00 C +ATOM 521 C GLY 55 -4.792 12.706 -4.656 1.00 0.00 C +ATOM 522 O GLY 55 -4.556 13.669 -3.921 1.00 0.00 O +ATOM 523 N TRP 56 -5.992 12.117 -4.766 1.00 0.00 N +ATOM 524 H TRP 56 -6.049 11.309 -5.313 1.00 0.00 H +ATOM 525 CA TRP 56 -7.249 12.562 -4.122 1.00 0.00 C +ATOM 526 CB TRP 56 -8.357 11.511 -4.358 1.00 0.00 C +ATOM 527 CG TRP 56 -9.732 12.047 -4.832 1.00 0.00 C +ATOM 528 CD2 TRP 56 -10.174 12.257 -6.193 1.00 0.00 C +ATOM 529 CE2 TRP 56 -11.520 12.715 -6.128 1.00 0.00 C +ATOM 530 CE3 TRP 56 -9.567 12.103 -7.461 1.00 0.00 C +ATOM 531 CD1 TRP 56 -10.801 12.379 -4.035 1.00 0.00 C +ATOM 532 NE1 TRP 56 -11.868 12.778 -4.805 1.00 0.00 N +ATOM 533 HE1 TRP 56 -12.738 13.061 -4.454 1.00 0.00 H +ATOM 534 CZ2 TRP 56 -12.278 13.025 -7.284 1.00 0.00 C +ATOM 535 CZ3 TRP 56 -10.323 12.412 -8.620 1.00 0.00 C +ATOM 536 CH2 TRP 56 -11.666 12.868 -8.515 1.00 0.00 C +ATOM 537 C TRP 56 -7.201 12.892 -2.622 1.00 0.00 C +ATOM 538 O TRP 56 -7.875 13.828 -2.176 1.00 0.00 O +ATOM 539 N ASP 57 -6.384 12.136 -1.869 1.00 0.00 N +ATOM 540 H ASP 57 -5.842 11.436 -2.294 1.00 0.00 H +ATOM 541 CA ASP 57 -6.203 12.251 -0.400 1.00 0.00 C +ATOM 542 CB ASP 57 -5.459 13.538 0.006 1.00 0.00 C +ATOM 543 CG ASP 57 -3.989 13.526 -0.397 1.00 0.00 C +ATOM 544 OD1 ASP 57 -3.158 12.994 0.372 1.00 0.00 O +ATOM 545 OD2 ASP 57 -3.659 14.070 -1.472 1.00 0.00 O +ATOM 546 C ASP 57 -7.516 12.084 0.390 1.00 0.00 C +ATOM 547 O ASP 57 -7.695 11.060 1.059 1.00 0.00 O +ATOM 548 N GLU 58 -8.398 13.097 0.329 1.00 0.00 N +ATOM 549 H GLU 58 -8.177 13.908 -0.179 1.00 0.00 H +ATOM 550 CA GLU 58 -9.721 13.107 0.990 1.00 0.00 C +ATOM 551 CB GLU 58 -9.610 13.121 2.529 1.00 0.00 C +ATOM 552 CG GLU 58 -10.651 12.248 3.247 1.00 0.00 C +ATOM 553 CD GLU 58 -10.532 12.309 4.754 1.00 0.00 C +ATOM 554 OE1 GLU 58 -9.740 11.529 5.321 1.00 0.00 O +ATOM 555 OE2 GLU 58 -11.225 13.144 5.373 1.00 0.00 O +ATOM 556 C GLU 58 -10.599 14.278 0.506 1.00 0.00 C +ATOM 557 O GLU 58 -10.253 15.451 0.694 1.00 0.00 O +ATOM 558 N HIS 59 -11.716 13.926 -0.143 1.00 0.00 N +ATOM 559 H HIS 59 -11.921 12.978 -0.303 1.00 0.00 H +ATOM 560 CA HIS 59 -12.717 14.871 -0.667 1.00 0.00 C +ATOM 561 CB HIS 59 -12.705 14.880 -2.212 1.00 0.00 C +ATOM 562 CG HIS 59 -13.263 16.131 -2.833 1.00 0.00 C +ATOM 563 CD2 HIS 59 -14.378 16.338 -3.576 1.00 0.00 C +ATOM 564 ND1 HIS 59 -12.640 17.358 -2.733 1.00 0.00 N +ATOM 565 HD1 HIS 59 -11.804 17.537 -2.254 1.00 0.00 H +ATOM 566 CE1 HIS 59 -13.344 18.265 -3.387 1.00 0.00 C +ATOM 567 NE2 HIS 59 -14.403 17.671 -3.907 1.00 0.00 N +ATOM 568 HE2 HIS 59 -15.096 18.111 -4.443 1.00 0.00 H +ATOM 569 C HIS 59 -14.068 14.358 -0.138 1.00 0.00 C +ATOM 570 O HIS 59 -15.022 15.133 0.010 1.00 0.00 O +ATOM 571 N SER 60 -14.112 13.048 0.147 1.00 0.00 N +ATOM 572 H SER 60 -13.318 12.484 0.013 1.00 0.00 H +ATOM 573 CA SER 60 -15.290 12.335 0.667 1.00 0.00 C +ATOM 574 CB SER 60 -15.863 11.405 -0.411 1.00 0.00 C +ATOM 575 OG SER 60 -17.106 10.844 -0.017 1.00 0.00 O +ATOM 576 HG SER 60 -17.764 11.533 0.101 1.00 0.00 H +ATOM 577 C SER 60 -14.882 11.503 1.893 1.00 0.00 C +ATOM 578 O SER 60 -13.728 11.063 1.986 1.00 0.00 O +ATOM 579 N LEU 61 -15.829 11.310 2.822 1.00 0.00 N +ATOM 580 H LEU 61 -16.724 11.697 2.705 1.00 0.00 H +ATOM 581 CA LEU 61 -15.631 10.530 4.060 1.00 0.00 C +ATOM 582 CB LEU 61 -15.582 11.453 5.301 1.00 0.00 C +ATOM 583 CG LEU 61 -14.516 12.545 5.526 1.00 0.00 C +ATOM 584 CD1 LEU 61 -14.852 13.866 4.805 1.00 0.00 C +ATOM 585 CD2 LEU 61 -14.420 12.808 7.020 1.00 0.00 C +ATOM 586 C LEU 61 -16.777 9.523 4.218 1.00 0.00 C +ATOM 587 O LEU 61 -16.545 8.377 4.621 1.00 0.00 O +ATOM 588 N ALA 62 -18.003 9.964 3.879 1.00 0.00 N +ATOM 589 H ALA 62 -18.111 10.884 3.551 1.00 0.00 H +ATOM 590 CA ALA 62 -19.274 9.193 3.944 1.00 0.00 C +ATOM 591 CB ALA 62 -19.393 8.208 2.751 1.00 0.00 C +ATOM 592 C ALA 62 -19.585 8.482 5.279 1.00 0.00 C +ATOM 593 O ALA 62 -18.924 7.495 5.634 1.00 0.00 O +ATOM 594 N LYS 63 -20.563 9.025 6.018 1.00 0.00 N +ATOM 595 H LYS 63 -21.035 9.829 5.704 1.00 0.00 H +ATOM 596 CA LYS 63 -21.013 8.496 7.320 1.00 0.00 C +ATOM 597 CB LYS 63 -20.728 9.497 8.470 1.00 0.00 C +ATOM 598 CG LYS 63 -21.102 10.976 8.227 1.00 0.00 C +ATOM 599 CD LYS 63 -20.766 11.838 9.439 1.00 0.00 C +ATOM 600 CE LYS 63 -21.128 13.306 9.221 1.00 0.00 C +ATOM 601 NZ LYS 63 -22.599 13.555 9.155 1.00 0.00 N +ATOM 602 HZ1 LYS 63 -23.007 13.014 8.366 1.00 0.00 H +ATOM 603 HZ2 LYS 63 -23.042 13.255 10.047 1.00 0.00 H +ATOM 604 HZ3 LYS 63 -22.773 14.569 9.006 1.00 0.00 H +ATOM 605 C LYS 63 -22.495 8.077 7.309 1.00 0.00 C +ATOM 606 O LYS 63 -23.316 8.726 6.651 1.00 0.00 O +ATOM 607 N ASP 64 -22.812 6.996 8.038 1.00 0.00 N +ATOM 608 H ASP 64 -22.118 6.514 8.539 1.00 0.00 H +ATOM 609 CA ASP 64 -24.177 6.448 8.153 1.00 0.00 C +ATOM 610 CB ASP 64 -24.187 4.953 7.766 1.00 0.00 C +ATOM 611 CG ASP 64 -25.538 4.483 7.220 1.00 0.00 C +ATOM 612 OD1 ASP 64 -25.748 4.560 5.989 1.00 0.00 O +ATOM 613 OD2 ASP 64 -26.381 4.022 8.021 1.00 0.00 O +ATOM 614 C ASP 64 -24.682 6.639 9.599 1.00 0.00 C +ATOM 615 O ASP 64 -23.911 6.472 10.553 1.00 0.00 O +ATOM 616 N PHE 65 -25.964 7.005 9.735 1.00 0.00 N +ATOM 617 H PHE 65 -26.531 7.135 8.943 1.00 0.00 H +ATOM 618 CA PHE 65 -26.622 7.239 11.035 1.00 0.00 C +ATOM 619 CB PHE 65 -27.219 8.680 11.113 1.00 0.00 C +ATOM 620 CG PHE 65 -27.947 9.156 9.847 1.00 0.00 C +ATOM 621 CD1 PHE 65 -27.247 9.838 8.822 1.00 0.00 C +ATOM 622 CD2 PHE 65 -29.339 8.957 9.693 1.00 0.00 C +ATOM 623 CE1 PHE 65 -27.920 10.315 7.664 1.00 0.00 C +ATOM 624 CE2 PHE 65 -30.027 9.428 8.540 1.00 0.00 C +ATOM 625 CZ PHE 65 -29.314 10.109 7.523 1.00 0.00 C +ATOM 626 C PHE 65 -27.677 6.178 11.409 1.00 0.00 C +ATOM 627 O PHE 65 -27.634 5.636 12.519 1.00 0.00 O +ATOM 628 N LEU 66 -28.606 5.898 10.483 1.00 0.00 N +ATOM 629 H LEU 66 -28.596 6.359 9.615 1.00 0.00 H +ATOM 630 CA LEU 66 -29.687 4.910 10.674 1.00 0.00 C +ATOM 631 CB LEU 66 -31.075 5.560 10.472 1.00 0.00 C +ATOM 632 CG LEU 66 -31.669 6.572 11.473 1.00 0.00 C +ATOM 633 CD1 LEU 66 -32.514 7.578 10.709 1.00 0.00 C +ATOM 634 CD2 LEU 66 -32.508 5.897 12.574 1.00 0.00 C +ATOM 635 C LEU 66 -29.542 3.703 9.738 1.00 0.00 C +ATOM 636 O LEU 66 -29.013 3.841 8.630 1.00 0.00 O +ATOM 637 N ASN 67 -30.048 2.540 10.193 1.00 0.00 N +ATOM 638 H ASN 67 -30.474 2.520 11.078 1.00 0.00 H +ATOM 639 CA ASN 67 -30.049 1.216 9.506 1.00 0.00 C +ATOM 640 CB ASN 67 -31.389 0.950 8.762 1.00 0.00 C +ATOM 641 CG ASN 67 -31.752 2.039 7.745 1.00 0.00 C +ATOM 642 OD1 ASN 67 -31.390 1.954 6.570 1.00 0.00 O +ATOM 643 ND2 ASN 67 -32.481 3.055 8.198 1.00 0.00 N +ATOM 644 HD21 ASN 67 -32.722 3.760 7.561 1.00 0.00 H +ATOM 645 HD22 ASN 67 -32.750 3.068 9.141 1.00 0.00 H +ATOM 646 C ASN 67 -28.844 0.767 8.648 1.00 0.00 C +ATOM 647 O ASN 67 -28.375 1.514 7.781 1.00 0.00 O +ATOM 648 N GLY 68 -28.378 -0.459 8.901 1.00 0.00 N +ATOM 649 H GLY 68 -28.783 -1.026 9.593 1.00 0.00 H +ATOM 650 CA GLY 68 -27.250 -1.029 8.175 1.00 0.00 C +ATOM 651 C GLY 68 -27.581 -2.398 7.607 1.00 0.00 C +ATOM 652 O GLY 68 -28.001 -3.290 8.355 1.00 0.00 O +ATOM 653 N GLN 69 -27.389 -2.555 6.292 1.00 0.00 N +ATOM 654 H GLN 69 -27.046 -1.799 5.769 1.00 0.00 H +ATOM 655 CA GLN 69 -27.663 -3.808 5.565 1.00 0.00 C +ATOM 656 CB GLN 69 -28.531 -3.541 4.325 1.00 0.00 C +ATOM 657 CG GLN 69 -29.966 -3.120 4.628 1.00 0.00 C +ATOM 658 CD GLN 69 -30.777 -2.870 3.371 1.00 0.00 C +ATOM 659 OE1 GLN 69 -30.828 -1.749 2.864 1.00 0.00 O +ATOM 660 NE2 GLN 69 -31.418 -3.916 2.861 1.00 0.00 N +ATOM 661 HE21 GLN 69 -31.345 -4.788 3.303 1.00 0.00 H +ATOM 662 HE22 GLN 69 -31.947 -3.770 2.049 1.00 0.00 H +ATOM 663 C GLN 69 -26.387 -4.558 5.149 1.00 0.00 C +ATOM 664 O GLN 69 -26.352 -5.793 5.217 1.00 0.00 O +ATOM 665 N ASP 70 -25.357 -3.810 4.726 1.00 0.00 N +ATOM 666 H ASP 70 -25.434 -2.831 4.697 1.00 0.00 H +ATOM 667 CA ASP 70 -24.065 -4.369 4.284 1.00 0.00 C +ATOM 668 CB ASP 70 -23.671 -3.806 2.903 1.00 0.00 C +ATOM 669 CG ASP 70 -24.624 -4.235 1.791 1.00 0.00 C +ATOM 670 OD1 ASP 70 -25.611 -3.510 1.534 1.00 0.00 O +ATOM 671 OD2 ASP 70 -24.378 -5.288 1.162 1.00 0.00 O +ATOM 672 C ASP 70 -22.926 -4.150 5.297 1.00 0.00 C +ATOM 673 O ASP 70 -22.607 -3.007 5.650 1.00 0.00 O +ATOM 674 N GLU 71 -22.354 -5.264 5.778 1.00 0.00 N +ATOM 675 H GLU 71 -22.681 -6.139 5.470 1.00 0.00 H +ATOM 676 CA GLU 71 -21.242 -5.308 6.754 1.00 0.00 C +ATOM 677 CB GLU 71 -21.079 -6.725 7.321 1.00 0.00 C +ATOM 678 CG GLU 71 -22.217 -7.186 8.230 1.00 0.00 C +ATOM 679 CD GLU 71 -22.008 -8.591 8.764 1.00 0.00 C +ATOM 680 OE1 GLU 71 -22.456 -9.553 8.104 1.00 0.00 O +ATOM 681 OE2 GLU 71 -21.398 -8.734 9.845 1.00 0.00 O +ATOM 682 C GLU 71 -19.894 -4.814 6.200 1.00 0.00 C +ATOM 683 O GLU 71 -19.127 -4.166 6.924 1.00 0.00 O +ATOM 684 N THR 72 -19.631 -5.119 4.919 1.00 0.00 N +ATOM 685 H THR 72 -20.309 -5.624 4.415 1.00 0.00 H +ATOM 686 CA THR 72 -18.391 -4.747 4.199 1.00 0.00 C +ATOM 687 CB THR 72 -18.352 -5.366 2.769 1.00 0.00 C +ATOM 688 OG1 THR 72 -19.581 -5.085 2.087 1.00 0.00 O +ATOM 689 HG1 THR 72 -19.689 -4.139 1.961 1.00 0.00 H +ATOM 690 CG2 THR 72 -18.138 -6.874 2.837 1.00 0.00 C +ATOM 691 C THR 72 -18.147 -3.225 4.112 1.00 0.00 C +ATOM 692 O THR 72 -17.000 -2.775 4.237 1.00 0.00 O +ATOM 693 N ASP 73 -19.232 -2.454 3.930 1.00 0.00 N +ATOM 694 H ASP 73 -20.115 -2.878 3.846 1.00 0.00 H +ATOM 695 CA ASP 73 -19.205 -0.978 3.845 1.00 0.00 C +ATOM 696 CG ASP 73 -20.821 -0.802 1.877 1.00 0.00 C +ATOM 697 OD1 ASP 73 -21.392 -1.885 1.625 1.00 0.00 O +ATOM 698 OD2 ASP 73 -20.480 0.006 0.986 1.00 0.00 O +ATOM 699 C ASP 73 -18.857 -0.327 5.197 1.00 0.00 C +ATOM 700 O ASP 73 -18.053 0.611 5.249 1.00 0.00 O +ATOM 701 CB ASP 73 -20.551 -0.438 3.332 1.00 0.00 C +ATOM 702 N PHE 74 -19.490 -0.828 6.268 1.00 0.00 N +ATOM 703 H PHE 74 -20.132 -1.563 6.144 1.00 0.00 H +ATOM 704 CA PHE 74 -19.303 -0.370 7.660 1.00 0.00 C +ATOM 705 CB PHE 74 -20.462 -0.878 8.547 1.00 0.00 C +ATOM 706 CG PHE 74 -21.772 -0.108 8.387 1.00 0.00 C +ATOM 707 CD1 PHE 74 -22.098 0.950 9.270 1.00 0.00 C +ATOM 708 CD2 PHE 74 -22.704 -0.455 7.380 1.00 0.00 C +ATOM 709 CE1 PHE 74 -23.330 1.651 9.154 1.00 0.00 C +ATOM 710 CE2 PHE 74 -23.939 0.236 7.251 1.00 0.00 C +ATOM 711 CZ PHE 74 -24.252 1.292 8.141 1.00 0.00 C +ATOM 712 C PHE 74 -17.949 -0.711 8.315 1.00 0.00 C +ATOM 713 O PHE 74 -17.413 0.097 9.083 1.00 0.00 O +ATOM 714 N LYS 75 -17.417 -1.901 7.998 1.00 0.00 N +ATOM 715 H LYS 75 -17.893 -2.485 7.364 1.00 0.00 H +ATOM 716 CA LYS 75 -16.139 -2.428 8.532 1.00 0.00 C +ATOM 717 CB LYS 75 -16.001 -3.922 8.214 1.00 0.00 C +ATOM 718 CG LYS 75 -16.833 -4.833 9.108 1.00 0.00 C +ATOM 719 CD LYS 75 -16.627 -6.301 8.751 1.00 0.00 C +ATOM 720 CE LYS 75 -17.353 -7.238 9.715 1.00 0.00 C +ATOM 721 NZ LYS 75 -18.842 -7.161 9.625 1.00 0.00 N +ATOM 722 HZ1 LYS 75 -19.153 -6.193 9.843 1.00 0.00 H +ATOM 723 HZ2 LYS 75 -19.144 -7.414 8.663 1.00 0.00 H +ATOM 724 HZ3 LYS 75 -19.265 -7.823 10.307 1.00 0.00 H +ATOM 725 C LYS 75 -14.837 -1.695 8.148 1.00 0.00 C +ATOM 726 O LYS 75 -13.927 -1.590 8.980 1.00 0.00 O +ATOM 727 N ASN 76 -14.763 -1.189 6.908 1.00 0.00 N +ATOM 728 H ASN 76 -15.529 -1.286 6.300 1.00 0.00 H +ATOM 729 CA ASN 76 -13.583 -0.470 6.369 1.00 0.00 C +ATOM 730 CB ASN 76 -13.728 -0.243 4.842 1.00 0.00 C +ATOM 731 CG ASN 76 -15.046 0.431 4.447 1.00 0.00 C +ATOM 732 OD1 ASN 76 -15.232 1.636 4.643 1.00 0.00 O +ATOM 733 ND2 ASN 76 -15.946 -0.343 3.858 1.00 0.00 N +ATOM 734 HD21 ASN 76 -15.744 -1.290 3.706 1.00 0.00 H +ATOM 735 HD22 ASN 76 -16.787 0.080 3.591 1.00 0.00 H +ATOM 736 C ASN 76 -13.172 0.841 7.091 1.00 0.00 C +ATOM 737 O ASN 76 -12.080 1.375 6.844 1.00 0.00 O +ATOM 738 N LYS 77 -14.040 1.318 8.003 1.00 0.00 N +ATOM 739 H LYS 77 -14.877 0.831 8.168 1.00 0.00 H +ATOM 740 CA LYS 77 -13.875 2.550 8.828 1.00 0.00 C +ATOM 741 CB LYS 77 -12.706 2.420 9.833 1.00 0.00 C +ATOM 742 CG LYS 77 -12.929 1.397 10.940 1.00 0.00 C +ATOM 743 CD LYS 77 -11.737 1.332 11.881 1.00 0.00 C +ATOM 744 CE LYS 77 -11.960 0.311 12.985 1.00 0.00 C +ATOM 745 NZ LYS 77 -10.800 0.237 13.915 1.00 0.00 N +ATOM 746 HZ1 LYS 77 -10.649 1.167 14.357 1.00 0.00 H +ATOM 747 HZ2 LYS 77 -9.948 -0.037 13.385 1.00 0.00 H +ATOM 748 HZ3 LYS 77 -10.991 -0.470 14.653 1.00 0.00 H +ATOM 749 C LYS 77 -13.774 3.885 8.054 1.00 0.00 C +ATOM 750 O LYS 77 -13.542 3.881 6.838 1.00 0.00 O +ATOM 751 N ASP 78 -13.952 5.006 8.771 1.00 0.00 N +ATOM 752 H ASP 78 -14.130 4.950 9.735 1.00 0.00 H +ATOM 753 CA ASP 78 -13.903 6.372 8.214 1.00 0.00 C +ATOM 754 CB ASP 78 -14.972 7.249 8.896 1.00 0.00 C +ATOM 755 CG ASP 78 -15.518 8.350 7.984 1.00 0.00 C +ATOM 756 OD1 ASP 78 -16.541 8.112 7.305 1.00 0.00 O +ATOM 757 OD2 ASP 78 -14.934 9.457 7.961 1.00 0.00 O +ATOM 758 C ASP 78 -12.504 7.005 8.384 1.00 0.00 C +ATOM 759 O ASP 78 -11.782 6.670 9.331 1.00 0.00 O +ATOM 760 N SER 79 -12.150 7.910 7.459 1.00 0.00 N +ATOM 761 H SER 79 -12.766 8.136 6.728 1.00 0.00 H +ATOM 762 CA SER 79 -10.862 8.630 7.440 1.00 0.00 C +ATOM 763 CB SER 79 -10.206 8.491 6.056 1.00 0.00 C +ATOM 764 OG SER 79 -8.897 9.036 6.037 1.00 0.00 O +ATOM 765 HG SER 79 -8.519 8.932 5.160 1.00 0.00 H +ATOM 766 C SER 79 -11.076 10.117 7.791 1.00 0.00 C +ATOM 767 O SER 79 -12.139 10.671 7.488 1.00 0.00 O +ATOM 768 N ASP 80 -10.070 10.739 8.424 1.00 0.00 N +ATOM 769 H ASP 80 -9.242 10.252 8.633 1.00 0.00 H +ATOM 770 CA ASP 80 -10.107 12.156 8.849 1.00 0.00 C +ATOM 771 CB ASP 80 -9.719 12.295 10.344 1.00 0.00 C +ATOM 772 CG ASP 80 -8.444 11.528 10.718 1.00 0.00 C +ATOM 773 OD1 ASP 80 -7.343 12.114 10.629 1.00 0.00 O +ATOM 774 OD2 ASP 80 -8.550 10.346 11.113 1.00 0.00 O +ATOM 775 C ASP 80 -9.301 13.140 7.972 1.00 0.00 C +ATOM 776 O ASP 80 -8.378 12.725 7.261 1.00 0.00 O +ATOM 777 N PHE 81 -9.655 14.438 8.056 1.00 0.00 N +ATOM 778 H PHE 81 -10.387 14.694 8.659 1.00 0.00 H +ATOM 779 CA PHE 81 -9.054 15.586 7.319 1.00 0.00 C +ATOM 780 CB PHE 81 -7.564 15.828 7.709 1.00 0.00 C +ATOM 781 CG PHE 81 -7.339 16.204 9.173 1.00 0.00 C +ATOM 782 CD1 PHE 81 -7.093 15.206 10.147 1.00 0.00 C +ATOM 783 CD2 PHE 81 -7.332 17.560 9.580 1.00 0.00 C +ATOM 784 CE1 PHE 81 -6.844 15.550 11.505 1.00 0.00 C +ATOM 785 CE2 PHE 81 -7.085 17.919 10.934 1.00 0.00 C +ATOM 786 CZ PHE 81 -6.840 16.911 11.899 1.00 0.00 C +ATOM 787 C PHE 81 -9.212 15.561 5.785 1.00 0.00 C +ATOM 788 O PHE 81 -8.671 14.671 5.116 1.00 0.00 O +ATOM 789 N ASN 82 -9.924 16.564 5.252 1.00 0.00 N +ATOM 790 H ASN 82 -10.292 17.266 5.834 1.00 0.00 H +ATOM 791 CA ASN 82 -10.211 16.717 3.811 1.00 0.00 C +ATOM 792 CB ASN 82 -11.584 17.399 3.634 1.00 0.00 C +ATOM 793 CG ASN 82 -12.345 16.912 2.406 1.00 0.00 C +ATOM 794 OD1 ASN 82 -13.123 15.959 2.481 1.00 0.00 O +ATOM 795 ND2 ASN 82 -12.137 17.580 1.275 1.00 0.00 N +ATOM 796 HD21 ASN 82 -12.620 17.286 0.476 1.00 0.00 H +ATOM 797 HD22 ASN 82 -11.514 18.338 1.274 1.00 0.00 H +ATOM 798 C ASN 82 -9.101 17.491 3.055 1.00 0.00 C +ATOM 799 O ASN 82 -8.835 18.664 3.356 1.00 0.00 O +ATOM 800 N LYS 83 -8.439 16.794 2.119 1.00 0.00 N +ATOM 801 H LYS 83 -8.665 15.852 1.952 1.00 0.00 H +ATOM 802 CA LYS 83 -7.352 17.337 1.278 1.00 0.00 C +ATOM 803 CB LYS 83 -5.989 16.753 1.689 1.00 0.00 C +ATOM 804 CG LYS 83 -5.449 17.271 3.017 1.00 0.00 C +ATOM 805 CD LYS 83 -4.062 16.711 3.311 1.00 0.00 C +ATOM 806 CE LYS 83 -3.503 17.219 4.638 1.00 0.00 C +ATOM 807 NZ LYS 83 -4.228 16.692 5.833 1.00 0.00 N +ATOM 808 HZ1 LYS 83 -4.165 15.654 5.846 1.00 0.00 H +ATOM 809 HZ2 LYS 83 -3.797 17.077 6.697 1.00 0.00 H +ATOM 810 HZ3 LYS 83 -5.227 16.978 5.786 1.00 0.00 H +ATOM 811 C LYS 83 -7.619 17.045 -0.209 1.00 0.00 C +ATOM 812 O LYS 83 -8.117 15.965 -0.548 1.00 0.00 O +ATOM 813 N THR 84 -7.256 17.998 -1.081 1.00 0.00 N +ATOM 814 H THR 84 -6.822 18.815 -0.744 1.00 0.00 H +ATOM 815 CA THR 84 -7.450 17.907 -2.547 1.00 0.00 C +ATOM 816 CB THR 84 -7.671 19.312 -3.177 1.00 0.00 C +ATOM 817 OG1 THR 84 -6.646 20.210 -2.732 1.00 0.00 O +ATOM 818 HG1 THR 84 -5.783 19.918 -3.038 1.00 0.00 H +ATOM 819 CG2 THR 84 -9.039 19.869 -2.796 1.00 0.00 C +ATOM 820 C THR 84 -6.316 17.190 -3.310 1.00 0.00 C +ATOM 821 O THR 84 -5.267 16.894 -2.726 1.00 0.00 O +ATOM 822 N LEU 85 -6.550 16.923 -4.606 1.00 0.00 N +ATOM 823 H LEU 85 -7.405 17.186 -5.011 1.00 0.00 H +ATOM 824 CA LEU 85 -5.599 16.249 -5.510 1.00 0.00 C +ATOM 825 CB LEU 85 -6.372 15.379 -6.543 1.00 0.00 C +ATOM 826 CG LEU 85 -7.663 15.814 -7.291 1.00 0.00 C +ATOM 827 CD1 LEU 85 -7.785 15.044 -8.587 1.00 0.00 C +ATOM 828 CD2 LEU 85 -8.936 15.633 -6.443 1.00 0.00 C +ATOM 829 C LEU 85 -4.606 17.216 -6.196 1.00 0.00 C +ATOM 830 O LEU 85 -5.023 18.202 -6.820 1.00 0.00 O +ATOM 831 N ALA 86 -3.306 16.929 -6.040 1.00 0.00 N +ATOM 832 H ALA 86 -3.030 16.138 -5.525 1.00 0.00 H +ATOM 833 CA ALA 86 -2.205 17.733 -6.600 1.00 0.00 C +ATOM 834 CB ALA 86 -1.503 18.509 -5.483 1.00 0.00 C +ATOM 835 C ALA 86 -1.178 16.895 -7.376 1.00 0.00 C +ATOM 836 O ALA 86 -1.145 15.666 -7.234 1.00 0.00 O +ATOM 837 N LYS 87 -0.356 17.577 -8.188 1.00 0.00 N +ATOM 838 H LYS 87 -0.444 18.552 -8.276 1.00 0.00 H +ATOM 839 CA LYS 87 0.719 16.971 -9.002 1.00 0.00 C +ATOM 840 CB LYS 87 0.343 16.886 -10.500 1.00 0.00 C +ATOM 841 CG LYS 87 -0.324 18.128 -11.133 1.00 0.00 C +ATOM 842 CD LYS 87 -0.636 17.897 -12.608 1.00 0.00 C +ATOM 843 CE LYS 87 -1.296 19.112 -13.255 1.00 0.00 C +ATOM 844 NZ LYS 87 -0.385 20.289 -13.387 1.00 0.00 N +ATOM 845 HZ1 LYS 87 0.433 20.029 -13.976 1.00 0.00 H +ATOM 846 HZ2 LYS 87 -0.055 20.579 -12.445 1.00 0.00 H +ATOM 847 HZ3 LYS 87 -0.897 21.076 -13.834 1.00 0.00 H +ATOM 848 C LYS 87 2.045 17.726 -8.824 1.00 0.00 C +ATOM 849 O LYS 87 2.064 18.965 -8.854 1.00 0.00 O +ATOM 850 N ILE 88 3.134 16.973 -8.615 1.00 0.00 N +ATOM 851 H ILE 88 3.062 15.993 -8.579 1.00 0.00 H +ATOM 852 CA ILE 88 4.492 17.521 -8.425 1.00 0.00 C +ATOM 853 CB ILE 88 4.933 17.561 -6.898 1.00 0.00 C +ATOM 854 CG2 ILE 88 4.295 18.781 -6.217 1.00 0.00 C +ATOM 855 CG1 ILE 88 4.594 16.246 -6.158 1.00 0.00 C +ATOM 856 CD1 ILE 88 5.609 15.827 -5.083 1.00 0.00 C +ATOM 857 C ILE 88 5.571 16.822 -9.278 1.00 0.00 C +ATOM 858 O ILE 88 6.426 17.497 -9.867 1.00 0.00 O +ATOM 859 N LYS 89 5.508 15.484 -9.344 1.00 0.00 N +ATOM 860 H LYS 89 4.790 14.998 -8.881 1.00 0.00 H +ATOM 861 CA LYS 89 6.470 14.650 -10.088 1.00 0.00 C +ATOM 862 CB LYS 89 7.224 13.724 -9.126 1.00 0.00 C +ATOM 863 CG LYS 89 8.328 14.416 -8.339 1.00 0.00 C +ATOM 864 CD LYS 89 9.039 13.450 -7.398 1.00 0.00 C +ATOM 865 CE LYS 89 10.248 14.095 -6.720 1.00 0.00 C +ATOM 866 NZ LYS 89 9.898 15.215 -5.796 1.00 0.00 N +ATOM 867 HZ1 LYS 89 10.767 15.601 -5.374 1.00 0.00 H +ATOM 868 HZ2 LYS 89 9.408 15.963 -6.327 1.00 0.00 H +ATOM 869 HZ3 LYS 89 9.275 14.861 -5.042 1.00 0.00 H +ATOM 870 C LYS 89 5.873 13.814 -11.224 1.00 0.00 C +ATOM 871 O LYS 89 6.496 13.692 -12.286 1.00 0.00 O +ATOM 872 N THR 90 4.662 13.270 -11.004 1.00 0.00 N +ATOM 873 H THR 90 4.207 13.446 -10.151 1.00 0.00 H +ATOM 874 CA THR 90 3.889 12.397 -11.935 1.00 0.00 C +ATOM 875 CB THR 90 2.957 13.211 -12.957 1.00 0.00 C +ATOM 876 OG1 THR 90 2.176 12.298 -13.740 1.00 0.00 O +ATOM 877 HG1 THR 90 1.598 11.785 -13.170 1.00 0.00 H +ATOM 878 CG2 THR 90 3.764 14.132 -13.896 1.00 0.00 C +ATOM 879 C THR 90 4.668 11.220 -12.619 1.00 0.00 C +ATOM 880 O THR 90 5.598 11.473 -13.399 1.00 0.00 O +ATOM 881 N PRO 91 4.322 9.932 -12.298 1.00 0.00 N +ATOM 882 CD PRO 91 3.455 9.568 -11.158 1.00 0.00 C +ATOM 883 CA PRO 91 4.931 8.695 -12.832 1.00 0.00 C +ATOM 884 CB PRO 91 4.155 7.600 -12.096 1.00 0.00 C +ATOM 885 CG PRO 91 3.945 8.189 -10.787 1.00 0.00 C +ATOM 886 C PRO 91 4.939 8.458 -14.365 1.00 0.00 C +ATOM 887 O PRO 91 5.099 7.315 -14.819 1.00 0.00 O +ATOM 888 N LYS 92 4.810 9.540 -15.145 1.00 0.00 N +ATOM 889 H LYS 92 4.685 10.428 -14.768 1.00 0.00 H +ATOM 890 CA LYS 92 4.825 9.495 -16.622 1.00 0.00 C +ATOM 891 CB LYS 92 4.077 10.702 -17.205 1.00 0.00 C +ATOM 892 CG LYS 92 2.567 10.679 -16.999 1.00 0.00 C +ATOM 893 CD LYS 92 1.904 11.902 -17.622 1.00 0.00 C +ATOM 894 CE LYS 92 0.388 11.892 -17.442 1.00 0.00 C +ATOM 895 NZ LYS 92 -0.300 10.825 -18.229 1.00 0.00 N +ATOM 896 HZ1 LYS 92 0.054 9.893 -17.933 1.00 0.00 H +ATOM 897 HZ2 LYS 92 -0.109 10.962 -19.242 1.00 0.00 H +ATOM 898 HZ3 LYS 92 -1.325 10.876 -18.060 1.00 0.00 H +ATOM 899 C LYS 92 6.288 9.473 -17.115 1.00 0.00 C +ATOM 900 O LYS 92 6.567 9.077 -18.255 1.00 0.00 O +ATOM 901 N GLU 93 7.198 9.881 -16.217 1.00 0.00 N +ATOM 902 H GLU 93 6.912 10.179 -15.325 1.00 0.00 H +ATOM 903 CA GLU 93 8.657 9.932 -16.439 1.00 0.00 C +ATOM 904 CB GLU 93 9.157 11.397 -16.584 1.00 0.00 C +ATOM 905 CG GLU 93 8.634 12.428 -15.559 1.00 0.00 C +ATOM 906 CD GLU 93 9.187 13.820 -15.797 1.00 0.00 C +ATOM 907 OE1 GLU 93 10.253 14.144 -15.232 1.00 0.00 O +ATOM 908 OE2 GLU 93 8.554 14.592 -16.549 1.00 0.00 O +ATOM 909 C GLU 93 9.397 9.185 -15.301 1.00 0.00 C +ATOM 910 O GLU 93 10.623 9.016 -15.353 1.00 0.00 O +ATOM 911 N VAL 94 8.613 8.694 -14.322 1.00 0.00 N +ATOM 912 H VAL 94 7.640 8.821 -14.382 1.00 0.00 H +ATOM 913 CA VAL 94 9.036 7.948 -13.098 1.00 0.00 C +ATOM 914 CB VAL 94 8.924 6.360 -13.238 1.00 0.00 C +ATOM 915 CG1 VAL 94 7.470 5.934 -13.285 1.00 0.00 C +ATOM 916 CG2 VAL 94 9.672 5.829 -14.479 1.00 0.00 C +ATOM 917 C VAL 94 10.341 8.327 -12.355 1.00 0.00 C +ATOM 918 O VAL 94 10.278 8.800 -11.214 1.00 0.00 O +ATOM 919 N ASN 95 11.499 8.132 -13.015 1.00 0.00 N +ATOM 920 H ASN 95 11.472 7.779 -13.932 1.00 0.00 H +ATOM 921 CA ASN 95 12.867 8.401 -12.496 1.00 0.00 C +ATOM 922 CB ASN 95 13.186 9.916 -12.447 1.00 0.00 C +ATOM 923 CG ASN 95 13.203 10.562 -13.827 1.00 0.00 C +ATOM 924 OD1 ASN 95 12.181 11.056 -14.308 1.00 0.00 O +ATOM 925 ND2 ASN 95 14.372 10.577 -14.462 1.00 0.00 N +ATOM 926 HD21 ASN 95 14.400 10.989 -15.351 1.00 0.00 H +ATOM 927 HD22 ASN 95 15.158 10.181 -14.029 1.00 0.00 H +ATOM 928 C ASN 95 13.186 7.722 -11.143 1.00 0.00 C +ATOM 929 O ASN 95 12.616 8.091 -10.105 1.00 0.00 O +ATOM 930 N ALA 96 14.042 6.693 -11.191 1.00 0.00 N +ATOM 931 H ALA 96 14.433 6.411 -12.047 1.00 0.00 H +ATOM 932 CA ALA 96 14.466 5.914 -10.014 1.00 0.00 C +ATOM 933 CB ALA 96 13.894 4.481 -10.093 1.00 0.00 C +ATOM 934 C ALA 96 16.004 5.895 -9.910 1.00 0.00 C +ATOM 935 O ALA 96 16.655 6.837 -10.379 1.00 0.00 O +ATOM 936 N ASP 97 16.566 4.838 -9.292 1.00 0.00 N +ATOM 937 H ASP 97 15.999 4.127 -8.923 1.00 0.00 H +ATOM 938 CA ASP 97 18.020 4.595 -9.065 1.00 0.00 C +ATOM 939 CB ASP 97 18.826 4.538 -10.386 1.00 0.00 C +ATOM 940 CG ASP 97 18.413 3.377 -11.284 1.00 0.00 C +ATOM 941 OD1 ASP 97 19.003 2.282 -11.160 1.00 0.00 O +ATOM 942 OD2 ASP 97 17.509 3.565 -12.128 1.00 0.00 O +ATOM 943 C ASP 97 18.715 5.529 -8.058 1.00 0.00 C +ATOM 944 O ASP 97 19.582 5.081 -7.297 1.00 0.00 O +ATOM 945 N ASP 98 18.321 6.810 -8.061 1.00 0.00 N +ATOM 946 H ASP 98 17.634 7.130 -8.678 1.00 0.00 H +ATOM 947 CA ASP 98 18.870 7.848 -7.168 1.00 0.00 C +ATOM 948 CB ASP 98 19.336 9.082 -7.983 1.00 0.00 C +ATOM 949 CG ASP 98 18.292 9.577 -8.994 1.00 0.00 C +ATOM 950 OD1 ASP 98 17.484 10.461 -8.635 1.00 0.00 O +ATOM 951 OD2 ASP 98 18.295 9.091 -10.147 1.00 0.00 O +ATOM 952 C ASP 98 17.893 8.243 -6.037 1.00 0.00 C +ATOM 953 O ASP 98 18.290 8.905 -5.068 1.00 0.00 O +ATOM 954 N TYR 99 16.636 7.793 -6.166 1.00 0.00 N +ATOM 955 H TYR 99 16.382 7.251 -6.945 1.00 0.00 H +ATOM 956 CA TYR 99 15.550 8.051 -5.200 1.00 0.00 C +ATOM 957 CB TYR 99 14.209 8.229 -5.954 1.00 0.00 C +ATOM 958 CG TYR 99 14.071 9.495 -6.808 1.00 0.00 C +ATOM 959 CD1 TYR 99 14.529 9.531 -8.150 1.00 0.00 C +ATOM 960 CE1 TYR 99 14.371 10.694 -8.953 1.00 0.00 C +ATOM 961 CD2 TYR 99 13.449 10.659 -6.292 1.00 0.00 C +ATOM 962 CE2 TYR 99 13.287 11.826 -7.089 1.00 0.00 C +ATOM 963 CZ TYR 99 13.750 11.832 -8.414 1.00 0.00 C +ATOM 964 OH TYR 99 13.594 12.961 -9.187 1.00 0.00 O +ATOM 965 HH TYR 99 13.957 12.818 -10.064 1.00 0.00 H +ATOM 966 C TYR 99 15.445 6.929 -4.145 1.00 0.00 C +ATOM 967 O TYR 99 14.420 6.792 -3.461 1.00 0.00 O +ATOM 968 N GLN 100 16.546 6.172 -4.003 1.00 0.00 N +ATOM 969 H GLN 100 17.336 6.359 -4.557 1.00 0.00 H +ATOM 970 CA GLN 100 16.735 5.029 -3.070 1.00 0.00 C +ATOM 971 CB GLN 100 17.629 5.419 -1.850 1.00 0.00 C +ATOM 972 CG GLN 100 17.356 6.765 -1.121 1.00 0.00 C +ATOM 973 CD GLN 100 16.288 6.687 -0.031 1.00 0.00 C +ATOM 974 OE1 GLN 100 15.250 7.339 -0.127 1.00 0.00 O +ATOM 975 NE2 GLN 100 16.556 5.913 1.019 1.00 0.00 N +ATOM 976 HE21 GLN 100 15.879 5.855 1.725 1.00 0.00 H +ATOM 977 HE22 GLN 100 17.410 5.433 1.052 1.00 0.00 H +ATOM 978 C GLN 100 15.539 4.146 -2.631 1.00 0.00 C +ATOM 979 O GLN 100 15.436 3.001 -3.082 1.00 0.00 O +ATOM 980 N ILE 101 14.641 4.691 -1.795 1.00 0.00 N +ATOM 981 H ILE 101 14.729 5.625 -1.514 1.00 0.00 H +ATOM 982 CA ILE 101 13.469 3.961 -1.274 1.00 0.00 C +ATOM 983 CB ILE 101 13.458 3.967 0.342 1.00 0.00 C +ATOM 984 CG2 ILE 101 13.115 5.366 0.920 1.00 0.00 C +ATOM 985 CG1 ILE 101 12.701 2.745 0.946 1.00 0.00 C +ATOM 986 CD1 ILE 101 11.141 2.810 1.123 1.00 0.00 C +ATOM 987 C ILE 101 12.123 4.431 -1.880 1.00 0.00 C +ATOM 988 O ILE 101 11.925 5.630 -2.113 1.00 0.00 O +ATOM 989 N PHE 102 11.232 3.461 -2.130 1.00 0.00 N +ATOM 990 H PHE 102 11.458 2.521 -1.955 1.00 0.00 H +ATOM 991 CA PHE 102 9.881 3.691 -2.669 1.00 0.00 C +ATOM 992 CB PHE 102 9.683 2.959 -4.035 1.00 0.00 C +ATOM 993 CG PHE 102 8.367 3.280 -4.760 1.00 0.00 C +ATOM 994 CD1 PHE 102 8.240 4.436 -5.566 1.00 0.00 C +ATOM 995 CD2 PHE 102 7.255 2.411 -4.649 1.00 0.00 C +ATOM 996 CE1 PHE 102 7.026 4.726 -6.248 1.00 0.00 C +ATOM 997 CE2 PHE 102 6.035 2.687 -5.325 1.00 0.00 C +ATOM 998 CZ PHE 102 5.921 3.848 -6.126 1.00 0.00 C +ATOM 999 C PHE 102 8.887 3.166 -1.617 1.00 0.00 C +ATOM 1000 O PHE 102 9.017 2.028 -1.144 1.00 0.00 O +ATOM 1001 N PHE 103 7.934 4.025 -1.237 1.00 0.00 N +ATOM 1002 H PHE 103 7.900 4.933 -1.611 1.00 0.00 H +ATOM 1003 CA PHE 103 6.884 3.706 -0.258 1.00 0.00 C +ATOM 1004 CB PHE 103 6.874 4.748 0.892 1.00 0.00 C +ATOM 1005 CG PHE 103 6.595 4.169 2.279 1.00 0.00 C +ATOM 1006 CD1 PHE 103 5.284 4.160 2.809 1.00 0.00 C +ATOM 1007 CD2 PHE 103 7.649 3.659 3.077 1.00 0.00 C +ATOM 1008 CE1 PHE 103 5.024 3.653 4.112 1.00 0.00 C +ATOM 1009 CE2 PHE 103 7.403 3.149 4.380 1.00 0.00 C +ATOM 1010 CZ PHE 103 6.086 3.146 4.899 1.00 0.00 C +ATOM 1011 C PHE 103 5.553 3.733 -1.020 1.00 0.00 C +ATOM 1012 O PHE 103 5.401 4.521 -1.954 1.00 0.00 O +ATOM 1013 N ALA 104 4.641 2.817 -0.683 1.00 0.00 N +ATOM 1014 H ALA 104 4.813 2.178 0.039 1.00 0.00 H +ATOM 1015 CA ALA 104 3.327 2.729 -1.333 1.00 0.00 C +ATOM 1016 CB ALA 104 3.249 1.483 -2.231 1.00 0.00 C +ATOM 1017 C ALA 104 2.200 2.709 -0.303 1.00 0.00 C +ATOM 1018 O ALA 104 2.285 1.983 0.693 1.00 0.00 O +ATOM 1019 N SER 105 1.175 3.540 -0.534 1.00 0.00 N +ATOM 1020 H SER 105 1.181 4.140 -1.313 1.00 0.00 H +ATOM 1021 CA SER 105 -0.014 3.630 0.328 1.00 0.00 C +ATOM 1022 CB SER 105 -0.422 5.095 0.559 1.00 0.00 C +ATOM 1023 OG SER 105 -1.477 5.204 1.501 1.00 0.00 O +ATOM 1024 HG SER 105 -2.267 4.767 1.173 1.00 0.00 H +ATOM 1025 C SER 105 -1.136 2.836 -0.370 1.00 0.00 C +ATOM 1026 O SER 105 -0.926 2.322 -1.476 1.00 0.00 O +ATOM 1027 N ALA 106 -2.306 2.748 0.270 1.00 0.00 N +ATOM 1028 H ALA 106 -2.447 3.218 1.117 1.00 0.00 H +ATOM 1029 CA ALA 106 -3.456 1.999 -0.247 1.00 0.00 C +ATOM 1030 CB ALA 106 -4.016 1.138 0.846 1.00 0.00 C +ATOM 1031 C ALA 106 -4.562 2.868 -0.844 1.00 0.00 C +ATOM 1032 O ALA 106 -4.430 4.094 -0.903 1.00 0.00 O +ATOM 1033 N GLY 107 -5.640 2.212 -1.284 1.00 0.00 N +ATOM 1034 H GLY 107 -5.704 1.233 -1.225 1.00 0.00 H +ATOM 1035 CA GLY 107 -6.776 2.895 -1.871 1.00 0.00 C +ATOM 1036 C GLY 107 -8.070 2.125 -1.701 1.00 0.00 C +ATOM 1037 O GLY 107 -8.850 2.035 -2.652 1.00 0.00 O +ATOM 1038 N HIS 108 -8.278 1.584 -0.487 1.00 0.00 N +ATOM 1039 H HIS 108 -7.584 1.719 0.193 1.00 0.00 H +ATOM 1040 CA HIS 108 -9.454 0.790 -0.037 1.00 0.00 C +ATOM 1041 CB HIS 108 -10.428 1.663 0.781 1.00 0.00 C +ATOM 1042 CG HIS 108 -10.091 1.756 2.242 1.00 0.00 C +ATOM 1043 CD2 HIS 108 -10.808 1.425 3.343 1.00 0.00 C +ATOM 1044 ND1 HIS 108 -8.892 2.256 2.706 1.00 0.00 N +ATOM 1045 HD1 HIS 108 -8.155 2.583 2.149 1.00 0.00 H +ATOM 1046 CE1 HIS 108 -8.885 2.229 4.027 1.00 0.00 C +ATOM 1047 NE2 HIS 108 -10.036 1.729 4.438 1.00 0.00 N +ATOM 1048 HE2 HIS 108 -10.297 1.596 5.373 1.00 0.00 H +ATOM 1049 C HIS 108 -10.249 -0.095 -1.012 1.00 0.00 C +ATOM 1050 O HIS 108 -10.479 -1.275 -0.725 1.00 0.00 O +ATOM 1051 N GLY 109 -10.660 0.480 -2.150 1.00 0.00 N +ATOM 1052 H GLY 109 -10.505 1.429 -2.324 1.00 0.00 H +ATOM 1053 CA GLY 109 -11.426 -0.229 -3.171 1.00 0.00 C +ATOM 1054 C GLY 109 -10.736 -1.384 -3.883 1.00 0.00 C +ATOM 1055 O GLY 109 -10.052 -2.191 -3.244 1.00 0.00 O +ATOM 1056 N THR 110 -10.941 -1.461 -5.202 1.00 0.00 N +ATOM 1057 H THR 110 -11.506 -0.784 -5.633 1.00 0.00 H +ATOM 1058 CA THR 110 -10.369 -2.504 -6.069 1.00 0.00 C +ATOM 1059 CB THR 110 -11.441 -3.067 -7.045 1.00 0.00 C +ATOM 1060 OG1 THR 110 -12.109 -1.987 -7.711 1.00 0.00 O +ATOM 1061 HG1 THR 110 -12.587 -1.444 -7.079 1.00 0.00 H +ATOM 1062 CG2 THR 110 -12.462 -3.909 -6.296 1.00 0.00 C +ATOM 1063 C THR 110 -9.178 -1.965 -6.880 1.00 0.00 C +ATOM 1064 O THR 110 -8.452 -2.739 -7.526 1.00 0.00 O +ATOM 1065 N LEU 111 -8.951 -0.642 -6.778 1.00 0.00 N +ATOM 1066 H LEU 111 -9.522 -0.096 -6.194 1.00 0.00 H +ATOM 1067 CA LEU 111 -7.884 0.125 -7.478 1.00 0.00 C +ATOM 1068 CB LEU 111 -6.446 -0.306 -7.035 1.00 0.00 C +ATOM 1069 CG LEU 111 -6.049 -0.334 -5.542 1.00 0.00 C +ATOM 1070 CD1 LEU 111 -6.176 -1.745 -4.945 1.00 0.00 C +ATOM 1071 CD2 LEU 111 -4.621 0.137 -5.385 1.00 0.00 C +ATOM 1072 C LEU 111 -8.101 0.008 -9.008 1.00 0.00 C +ATOM 1073 O LEU 111 -7.884 -1.061 -9.593 1.00 0.00 O +ATOM 1074 N PHE 112 -8.613 1.089 -9.617 1.00 0.00 N +ATOM 1075 H PHE 112 -8.791 1.897 -9.085 1.00 0.00 H +ATOM 1076 CA PHE 112 -8.936 1.174 -11.061 1.00 0.00 C +ATOM 1077 CB PHE 112 -9.579 2.544 -11.389 1.00 0.00 C +ATOM 1078 CG PHE 112 -11.075 2.634 -11.089 1.00 0.00 C +ATOM 1079 CD1 PHE 112 -12.029 2.371 -12.102 1.00 0.00 C +ATOM 1080 CD2 PHE 112 -11.542 3.012 -9.807 1.00 0.00 C +ATOM 1081 CE1 PHE 112 -13.423 2.480 -11.846 1.00 0.00 C +ATOM 1082 CE2 PHE 112 -12.935 3.125 -9.536 1.00 0.00 C +ATOM 1083 CZ PHE 112 -13.877 2.858 -10.560 1.00 0.00 C +ATOM 1084 C PHE 112 -7.826 0.860 -12.078 1.00 0.00 C +ATOM 1085 O PHE 112 -8.111 0.300 -13.145 1.00 0.00 O +ATOM 1086 N ASP 113 -6.579 1.208 -11.737 1.00 0.00 N +ATOM 1087 H ASP 113 -6.401 1.645 -10.876 1.00 0.00 H +ATOM 1088 CA ASP 113 -5.408 0.972 -12.598 1.00 0.00 C +ATOM 1089 CB ASP 113 -4.585 2.261 -12.765 1.00 0.00 C +ATOM 1090 CG ASP 113 -5.328 3.340 -13.548 1.00 0.00 C +ATOM 1091 OD1 ASP 113 -5.183 3.386 -14.790 1.00 0.00 O +ATOM 1092 OD2 ASP 113 -6.043 4.152 -12.922 1.00 0.00 O +ATOM 1093 C ASP 113 -4.523 -0.161 -12.061 1.00 0.00 C +ATOM 1094 O ASP 113 -4.031 -0.981 -12.843 1.00 0.00 O +ATOM 1095 N TYR 114 -4.379 -0.226 -10.729 1.00 0.00 N +ATOM 1096 H TYR 114 -4.830 0.428 -10.150 1.00 0.00 H +ATOM 1097 CA TYR 114 -3.566 -1.240 -10.026 1.00 0.00 C +ATOM 1098 CB TYR 114 -2.936 -0.628 -8.747 1.00 0.00 C +ATOM 1099 CG TYR 114 -2.407 0.818 -8.832 1.00 0.00 C +ATOM 1100 CD1 TYR 114 -2.543 1.690 -7.734 1.00 0.00 C +ATOM 1101 CE1 TYR 114 -2.054 3.026 -7.779 1.00 0.00 C +ATOM 1102 CD2 TYR 114 -1.763 1.321 -9.992 1.00 0.00 C +ATOM 1103 CE2 TYR 114 -1.273 2.656 -10.049 1.00 0.00 C +ATOM 1104 CZ TYR 114 -1.423 3.497 -8.937 1.00 0.00 C +ATOM 1105 OH TYR 114 -0.946 4.787 -8.978 1.00 0.00 O +ATOM 1106 HH TYR 114 -0.497 4.943 -9.811 1.00 0.00 H +ATOM 1107 C TYR 114 -4.454 -2.464 -9.663 1.00 0.00 C +ATOM 1108 O TYR 114 -5.661 -2.281 -9.491 1.00 0.00 O +ATOM 1109 N PRO 115 -3.894 -3.716 -9.548 1.00 0.00 N +ATOM 1110 CD PRO 115 -4.858 -4.748 -9.108 1.00 0.00 C +ATOM 1111 CA PRO 115 -2.553 -4.338 -9.675 1.00 0.00 C +ATOM 1112 CB PRO 115 -2.794 -5.781 -9.212 1.00 0.00 C +ATOM 1113 CG PRO 115 -3.987 -5.693 -8.336 1.00 0.00 C +ATOM 1114 C PRO 115 -1.909 -4.333 -11.078 1.00 0.00 C +ATOM 1115 O PRO 115 -0.683 -4.216 -11.190 1.00 0.00 O +ATOM 1116 N LYS 116 -2.741 -4.456 -12.123 1.00 0.00 N +ATOM 1117 H LYS 116 -3.710 -4.532 -11.978 1.00 0.00 H +ATOM 1118 CA LYS 116 -2.295 -4.488 -13.530 1.00 0.00 C +ATOM 1119 CB LYS 116 -3.180 -5.442 -14.353 1.00 0.00 C +ATOM 1120 CG LYS 116 -3.016 -6.920 -14.013 1.00 0.00 C +ATOM 1121 CD LYS 116 -3.926 -7.790 -14.872 1.00 0.00 C +ATOM 1122 CE LYS 116 -3.778 -9.275 -14.548 1.00 0.00 C +ATOM 1123 NZ LYS 116 -2.457 -9.846 -14.951 1.00 0.00 N +ATOM 1124 HZ1 LYS 116 -2.424 -10.855 -14.702 1.00 0.00 H +ATOM 1125 HZ2 LYS 116 -1.695 -9.341 -14.453 1.00 0.00 H +ATOM 1126 HZ3 LYS 116 -2.331 -9.737 -15.977 1.00 0.00 H +ATOM 1127 C LYS 116 -2.204 -3.092 -14.191 1.00 0.00 C +ATOM 1128 O LYS 116 -3.074 -2.699 -14.984 1.00 0.00 O +ATOM 1129 N ALA 117 -1.158 -2.344 -13.811 1.00 0.00 N +ATOM 1130 H ALA 117 -0.515 -2.685 -13.150 1.00 0.00 H +ATOM 1131 CA ALA 117 -0.873 -0.991 -14.321 1.00 0.00 C +ATOM 1132 CB ALA 117 -1.135 0.060 -13.244 1.00 0.00 C +ATOM 1133 C ALA 117 0.585 -0.911 -14.775 1.00 0.00 C +ATOM 1134 O ALA 117 1.463 -1.507 -14.142 1.00 0.00 O +ATOM 1135 N LYS 118 0.826 -0.174 -15.867 1.00 0.00 N +ATOM 1136 H LYS 118 0.080 0.274 -16.325 1.00 0.00 H +ATOM 1137 CA LYS 118 2.166 0.030 -16.455 1.00 0.00 C +ATOM 1138 CB LYS 118 2.055 0.633 -17.864 1.00 0.00 C +ATOM 1139 CG LYS 118 1.470 -0.305 -18.915 1.00 0.00 C +ATOM 1140 CD LYS 118 1.396 0.372 -20.280 1.00 0.00 C +ATOM 1141 CE LYS 118 0.813 -0.550 -21.350 1.00 0.00 C +ATOM 1142 NZ LYS 118 1.704 -1.696 -21.702 1.00 0.00 N +ATOM 1143 HZ1 LYS 118 2.609 -1.333 -22.064 1.00 0.00 H +ATOM 1144 HZ2 LYS 118 1.877 -2.274 -20.854 1.00 0.00 H +ATOM 1145 HZ3 LYS 118 1.247 -2.279 -22.432 1.00 0.00 H +ATOM 1146 C LYS 118 3.105 0.892 -15.591 1.00 0.00 C +ATOM 1147 O LYS 118 4.267 0.527 -15.400 1.00 0.00 O +ATOM 1148 N ASP 119 2.571 1.992 -15.037 1.00 0.00 N +ATOM 1149 H ASP 119 1.620 2.190 -15.187 1.00 0.00 H +ATOM 1150 CA ASP 119 3.311 2.956 -14.191 1.00 0.00 C +ATOM 1151 CB ASP 119 2.491 4.247 -14.004 1.00 0.00 C +ATOM 1152 CG ASP 119 2.220 4.976 -15.318 1.00 0.00 C +ATOM 1153 OD1 ASP 119 1.175 4.704 -15.949 1.00 0.00 O +ATOM 1154 OD2 ASP 119 3.042 5.832 -15.712 1.00 0.00 O +ATOM 1155 C ASP 119 3.766 2.426 -12.816 1.00 0.00 C +ATOM 1156 O ASP 119 4.930 2.617 -12.439 1.00 0.00 O +ATOM 1157 N LEU 120 2.858 1.746 -12.097 1.00 0.00 N +ATOM 1158 H LEU 120 1.956 1.614 -12.466 1.00 0.00 H +ATOM 1159 CA LEU 120 3.115 1.162 -10.762 1.00 0.00 C +ATOM 1160 CB LEU 120 1.788 0.718 -10.105 1.00 0.00 C +ATOM 1161 CG LEU 120 1.649 0.187 -8.661 1.00 0.00 C +ATOM 1162 CD1 LEU 120 1.080 1.238 -7.705 1.00 0.00 C +ATOM 1163 CD2 LEU 120 0.754 -1.040 -8.690 1.00 0.00 C +ATOM 1164 C LEU 120 4.106 -0.018 -10.835 1.00 0.00 C +ATOM 1165 O LEU 120 5.038 -0.099 -10.025 1.00 0.00 O +ATOM 1166 N GLN 121 3.887 -0.912 -11.810 1.00 0.00 N +ATOM 1167 H GLN 121 3.133 -0.786 -12.428 1.00 0.00 H +ATOM 1168 CA GLN 121 4.724 -2.102 -12.031 1.00 0.00 C +ATOM 1169 CB GLN 121 4.035 -3.085 -12.986 1.00 0.00 C +ATOM 1170 CG GLN 121 2.847 -3.830 -12.382 1.00 0.00 C +ATOM 1171 CD GLN 121 2.224 -4.819 -13.350 1.00 0.00 C +ATOM 1172 OE1 GLN 121 2.639 -5.976 -13.426 1.00 0.00 O +ATOM 1173 NE2 GLN 121 1.218 -4.370 -14.093 1.00 0.00 N +ATOM 1174 HE21 GLN 121 0.808 -4.997 -14.724 1.00 0.00 H +ATOM 1175 HE22 GLN 121 0.919 -3.442 -13.989 1.00 0.00 H +ATOM 1176 C GLN 121 6.144 -1.749 -12.512 1.00 0.00 C +ATOM 1177 O GLN 121 7.111 -2.393 -12.091 1.00 0.00 O +ATOM 1178 N ASP 122 6.254 -0.715 -13.361 1.00 0.00 N +ATOM 1179 H ASP 122 5.442 -0.247 -13.669 1.00 0.00 H +ATOM 1180 CA ASP 122 7.538 -0.214 -13.901 1.00 0.00 C +ATOM 1181 CB ASP 122 7.296 0.740 -15.088 1.00 0.00 C +ATOM 1182 CG ASP 122 8.432 0.722 -16.116 1.00 0.00 C +ATOM 1183 OD1 ASP 122 9.381 1.524 -15.976 1.00 0.00 O +ATOM 1184 OD2 ASP 122 8.364 -0.084 -17.070 1.00 0.00 O +ATOM 1185 C ASP 122 8.388 0.485 -12.814 1.00 0.00 C +ATOM 1186 O ASP 122 9.594 0.232 -12.725 1.00 0.00 O +ATOM 1187 N ILE 123 7.744 1.323 -11.984 1.00 0.00 N +ATOM 1188 H ILE 123 6.774 1.455 -12.097 1.00 0.00 H +ATOM 1189 CA ILE 123 8.407 2.075 -10.894 1.00 0.00 C +ATOM 1190 CB ILE 123 7.490 3.276 -10.370 1.00 0.00 C +ATOM 1191 CG2 ILE 123 6.290 2.751 -9.540 1.00 0.00 C +ATOM 1192 CG1 ILE 123 8.339 4.332 -9.628 1.00 0.00 C +ATOM 1193 CD1 ILE 123 7.777 5.765 -9.631 1.00 0.00 C +ATOM 1194 C ILE 123 8.912 1.127 -9.769 1.00 0.00 C +ATOM 1195 O ILE 123 10.019 1.319 -9.248 1.00 0.00 O +ATOM 1196 N ALA 124 8.098 0.113 -9.433 1.00 0.00 N +ATOM 1197 H ALA 124 7.223 0.016 -9.873 1.00 0.00 H +ATOM 1198 CA ALA 124 8.418 -0.902 -8.408 1.00 0.00 C +ATOM 1199 CB ALA 124 7.179 -1.725 -8.061 1.00 0.00 C +ATOM 1200 C ALA 124 9.565 -1.819 -8.875 1.00 0.00 C +ATOM 1201 O ALA 124 10.440 -2.176 -8.078 1.00 0.00 O +ATOM 1202 N SER 125 9.551 -2.167 -10.173 1.00 0.00 N +ATOM 1203 H SER 125 8.815 -1.856 -10.751 1.00 0.00 H +ATOM 1204 CA SER 125 10.572 -3.017 -10.825 1.00 0.00 C +ATOM 1205 CB SER 125 10.103 -3.446 -12.222 1.00 0.00 C +ATOM 1206 OG SER 125 10.966 -4.419 -12.791 1.00 0.00 O +ATOM 1207 HG SER 125 10.644 -4.663 -13.661 1.00 0.00 H +ATOM 1208 C SER 125 11.925 -2.285 -10.920 1.00 0.00 C +ATOM 1209 O SER 125 12.981 -2.908 -10.754 1.00 0.00 O +ATOM 1210 N GLU 126 11.868 -0.967 -11.178 1.00 0.00 N +ATOM 1211 H GLU 126 10.994 -0.536 -11.309 1.00 0.00 H +ATOM 1212 CA GLU 126 13.050 -0.086 -11.289 1.00 0.00 C +ATOM 1213 CB GLU 126 12.670 1.274 -11.889 1.00 0.00 C +ATOM 1214 CG GLU 126 12.510 1.269 -13.405 1.00 0.00 C +ATOM 1215 CD GLU 126 12.130 2.630 -13.959 1.00 0.00 C +ATOM 1216 OE1 GLU 126 10.918 2.913 -14.067 1.00 0.00 O +ATOM 1217 OE2 GLU 126 13.043 3.416 -14.290 1.00 0.00 O +ATOM 1218 C GLU 126 13.772 0.110 -9.946 1.00 0.00 C +ATOM 1219 O GLU 126 15.004 0.042 -9.899 1.00 0.00 O +ATOM 1220 N ILE 127 12.998 0.330 -8.869 1.00 0.00 N +ATOM 1221 H ILE 127 12.019 0.379 -8.985 1.00 0.00 H +ATOM 1222 CA ILE 127 13.522 0.514 -7.498 1.00 0.00 C +ATOM 1223 CB ILE 127 12.431 1.179 -6.527 1.00 0.00 C +ATOM 1224 CG2 ILE 127 11.294 0.208 -6.180 1.00 0.00 C +ATOM 1225 CG1 ILE 127 13.076 1.783 -5.263 1.00 0.00 C +ATOM 1226 CD1 ILE 127 13.160 3.321 -5.252 1.00 0.00 C +ATOM 1227 C ILE 127 14.116 -0.825 -6.975 1.00 0.00 C +ATOM 1228 O ILE 127 15.121 -0.823 -6.257 1.00 0.00 O +ATOM 1229 N TYR 128 13.465 -1.936 -7.353 1.00 0.00 N +ATOM 1230 H TYR 128 12.647 -1.851 -7.897 1.00 0.00 H +ATOM 1231 CA TYR 128 13.863 -3.319 -7.008 1.00 0.00 C +ATOM 1232 CB TYR 128 12.725 -4.311 -7.391 1.00 0.00 C +ATOM 1233 CG TYR 128 12.892 -5.790 -6.996 1.00 0.00 C +ATOM 1234 CD1 TYR 128 13.408 -6.735 -7.917 1.00 0.00 C +ATOM 1235 CE1 TYR 128 13.537 -8.109 -7.573 1.00 0.00 C +ATOM 1236 CD2 TYR 128 12.506 -6.258 -5.716 1.00 0.00 C +ATOM 1237 CE2 TYR 128 12.633 -7.630 -5.365 1.00 0.00 C +ATOM 1238 CZ TYR 128 13.148 -8.544 -6.298 1.00 0.00 C +ATOM 1239 OH TYR 128 13.273 -9.873 -5.962 1.00 0.00 O +ATOM 1240 HH TYR 128 12.968 -10.021 -5.064 1.00 0.00 H +ATOM 1241 C TYR 128 15.182 -3.684 -7.729 1.00 0.00 C +ATOM 1242 O TYR 128 16.018 -4.405 -7.171 1.00 0.00 O +ATOM 1243 N ALA 129 15.338 -3.171 -8.959 1.00 0.00 N +ATOM 1244 H ALA 129 14.628 -2.606 -9.343 1.00 0.00 H +ATOM 1245 CA ALA 129 16.509 -3.392 -9.832 1.00 0.00 C +ATOM 1246 CB ALA 129 16.202 -2.913 -11.246 1.00 0.00 C +ATOM 1247 C ALA 129 17.836 -2.778 -9.345 1.00 0.00 C +ATOM 1248 O ALA 129 18.893 -3.393 -9.522 1.00 0.00 O +ATOM 1249 N ASN 130 17.770 -1.583 -8.738 1.00 0.00 N +ATOM 1250 H ASN 130 16.903 -1.136 -8.619 1.00 0.00 H +ATOM 1251 CA ASN 130 18.951 -0.863 -8.214 1.00 0.00 C +ATOM 1252 CB ASN 130 18.760 0.674 -8.295 1.00 0.00 C +ATOM 1253 CG ASN 130 17.455 1.166 -7.650 1.00 0.00 C +ATOM 1254 OD1 ASN 130 17.304 1.159 -6.424 1.00 0.00 O +ATOM 1255 ND2 ASN 130 16.529 1.630 -8.479 1.00 0.00 N +ATOM 1256 HD21 ASN 130 15.692 1.955 -8.088 1.00 0.00 H +ATOM 1257 HD22 ASN 130 16.706 1.633 -9.444 1.00 0.00 H +ATOM 1258 C ASN 130 19.381 -1.287 -6.796 1.00 0.00 C +ATOM 1259 O ASN 130 20.577 -1.458 -6.534 1.00 0.00 O +ATOM 1260 N GLY 131 18.396 -1.449 -5.905 1.00 0.00 N +ATOM 1261 H GLY 131 17.457 -1.303 -6.155 1.00 0.00 H +ATOM 1262 CA GLY 131 18.648 -1.846 -4.525 1.00 0.00 C +ATOM 1263 C GLY 131 18.488 -0.703 -3.538 1.00 0.00 C +ATOM 1264 O GLY 131 19.446 0.036 -3.286 1.00 0.00 O +ATOM 1265 N GLY 132 17.279 -0.567 -2.989 1.00 0.00 N +ATOM 1266 H GLY 132 16.561 -1.190 -3.229 1.00 0.00 H +ATOM 1267 CA GLY 132 16.989 0.489 -2.032 1.00 0.00 C +ATOM 1268 C GLY 132 15.722 0.252 -1.230 1.00 0.00 C +ATOM 1269 O GLY 132 15.173 1.199 -0.658 1.00 0.00 O +ATOM 1270 N VAL 133 15.278 -1.016 -1.174 1.00 0.00 N +ATOM 1271 H VAL 133 15.794 -1.699 -1.654 1.00 0.00 H +ATOM 1272 CA VAL 133 14.068 -1.511 -0.453 1.00 0.00 C +ATOM 1273 CB VAL 133 14.217 -1.447 1.139 1.00 0.00 C +ATOM 1274 CG1 VAL 133 13.120 -2.265 1.846 1.00 0.00 C +ATOM 1275 CG2 VAL 133 15.590 -1.961 1.576 1.00 0.00 C +ATOM 1276 C VAL 133 12.728 -0.864 -0.902 1.00 0.00 C +ATOM 1277 O VAL 133 12.678 0.338 -1.189 1.00 0.00 O +ATOM 1278 N VAL 134 11.671 -1.690 -0.975 1.00 0.00 N +ATOM 1279 H VAL 134 11.772 -2.643 -0.759 1.00 0.00 H +ATOM 1280 CA VAL 134 10.310 -1.267 -1.371 1.00 0.00 C +ATOM 1281 CB VAL 134 9.801 -1.975 -2.697 1.00 0.00 C +ATOM 1282 CG1 VAL 134 8.844 -1.055 -3.466 1.00 0.00 C +ATOM 1283 CG2 VAL 134 10.966 -2.386 -3.601 1.00 0.00 C +ATOM 1284 C VAL 134 9.338 -1.594 -0.213 1.00 0.00 C +ATOM 1285 O VAL 134 9.433 -2.668 0.397 1.00 0.00 O +ATOM 1286 N ALA 135 8.448 -0.641 0.100 1.00 0.00 N +ATOM 1287 H ALA 135 8.439 0.211 -0.388 1.00 0.00 H +ATOM 1288 CA ALA 135 7.437 -0.777 1.166 1.00 0.00 C +ATOM 1289 CB ALA 135 7.785 0.129 2.358 1.00 0.00 C +ATOM 1290 C ALA 135 6.034 -0.444 0.638 1.00 0.00 C +ATOM 1291 O ALA 135 5.864 0.552 -0.070 1.00 0.00 O +ATOM 1292 N ALA 136 5.058 -1.314 0.936 1.00 0.00 N +ATOM 1293 H ALA 136 5.258 -2.122 1.458 1.00 0.00 H +ATOM 1294 CA ALA 136 3.648 -1.152 0.527 1.00 0.00 C +ATOM 1295 CB ALA 136 3.285 -2.178 -0.541 1.00 0.00 C +ATOM 1296 C ALA 136 2.735 -1.311 1.748 1.00 0.00 C +ATOM 1297 O ALA 136 2.922 -2.246 2.527 1.00 0.00 O +ATOM 1298 N VAL 137 1.739 -0.424 1.895 1.00 0.00 N +ATOM 1299 H VAL 137 1.589 0.271 1.223 1.00 0.00 H +ATOM 1300 CA VAL 137 0.794 -0.448 3.035 1.00 0.00 C +ATOM 1301 CB VAL 137 0.748 0.940 3.806 1.00 0.00 C +ATOM 1302 CG1 VAL 137 0.258 0.749 5.252 1.00 0.00 C +ATOM 1303 CG2 VAL 137 2.119 1.605 3.820 1.00 0.00 C +ATOM 1304 C VAL 137 -0.629 -0.872 2.592 1.00 0.00 C +ATOM 1305 O VAL 137 -1.050 -0.573 1.468 1.00 0.00 O +ATOM 1306 N CYS 138 -1.341 -1.562 3.503 1.00 0.00 N +ATOM 1307 H CYS 138 -0.942 -1.729 4.379 1.00 0.00 H +ATOM 1308 CA CYS 138 -2.723 -2.099 3.361 1.00 0.00 C +ATOM 1309 CB CYS 138 -3.775 -1.019 3.677 1.00 0.00 C +ATOM 1310 SG CYS 138 -5.486 -1.607 3.813 1.00 0.00 S +ATOM 1311 C CYS 138 -3.056 -2.895 2.075 1.00 0.00 C +ATOM 1312 O CYS 138 -2.958 -4.123 2.078 1.00 0.00 O +ATOM 1313 N HIS 139 -3.575 -2.203 1.054 1.00 0.00 N +ATOM 1314 H HIS 139 -3.755 -1.250 1.168 1.00 0.00 H +ATOM 1315 CA HIS 139 -3.910 -2.740 -0.273 1.00 0.00 C +ATOM 1316 CB HIS 139 -4.887 -1.827 -1.015 1.00 0.00 C +ATOM 1317 CG HIS 139 -6.194 -2.484 -1.353 1.00 0.00 C +ATOM 1318 CD2 HIS 139 -7.446 -2.281 -0.875 1.00 0.00 C +ATOM 1319 ND1 HIS 139 -6.304 -3.490 -2.290 1.00 0.00 N +ATOM 1320 HD1 HIS 139 -5.567 -3.864 -2.816 1.00 0.00 H +ATOM 1321 CE1 HIS 139 -7.564 -3.880 -2.372 1.00 0.00 C +ATOM 1322 NE2 HIS 139 -8.277 -3.162 -1.524 1.00 0.00 N +ATOM 1323 HE2 HIS 139 -9.243 -3.244 -1.380 1.00 0.00 H +ATOM 1324 C HIS 139 -2.650 -3.034 -1.090 1.00 0.00 C +ATOM 1325 O HIS 139 -2.667 -3.858 -2.014 1.00 0.00 O +ATOM 1326 N GLY 140 -1.578 -2.299 -0.756 1.00 0.00 N +ATOM 1327 H GLY 140 -1.626 -1.638 -0.035 1.00 0.00 H +ATOM 1328 CA GLY 140 -0.285 -2.412 -1.426 1.00 0.00 C +ATOM 1329 C GLY 140 0.253 -3.844 -1.497 1.00 0.00 C +ATOM 1330 O GLY 140 0.783 -4.186 -2.561 1.00 0.00 O +ATOM 1331 N PRO 141 0.190 -4.689 -0.421 1.00 0.00 N +ATOM 1332 CD PRO 141 0.053 -4.337 1.007 1.00 0.00 C +ATOM 1333 CA PRO 141 0.688 -6.075 -0.524 1.00 0.00 C +ATOM 1334 CB PRO 141 0.418 -6.661 0.874 1.00 0.00 C +ATOM 1335 CG PRO 141 -0.406 -5.626 1.599 1.00 0.00 C +ATOM 1336 C PRO 141 -0.075 -6.847 -1.625 1.00 0.00 C +ATOM 1337 O PRO 141 0.512 -7.682 -2.320 1.00 0.00 O +ATOM 1338 N ALA 142 -1.371 -6.518 -1.772 1.00 0.00 N +ATOM 1339 H ALA 142 -1.774 -5.837 -1.189 1.00 0.00 H +ATOM 1340 CA ALA 142 -2.284 -7.112 -2.770 1.00 0.00 C +ATOM 1341 CB ALA 142 -3.740 -6.723 -2.468 1.00 0.00 C +ATOM 1342 C ALA 142 -1.910 -6.734 -4.214 1.00 0.00 C +ATOM 1343 O ALA 142 -1.904 -7.607 -5.089 1.00 0.00 O +ATOM 1344 N ILE 143 -1.622 -5.444 -4.455 1.00 0.00 N +ATOM 1345 H ILE 143 -1.685 -4.783 -3.728 1.00 0.00 H +ATOM 1346 CA ILE 143 -1.208 -4.947 -5.790 1.00 0.00 C +ATOM 1347 CB ILE 143 -1.397 -3.383 -5.976 1.00 0.00 C +ATOM 1348 CG2 ILE 143 -2.903 -3.058 -5.972 1.00 0.00 C +ATOM 1349 CG1 ILE 143 -0.629 -2.571 -4.912 1.00 0.00 C +ATOM 1350 CD1 ILE 143 -0.336 -1.099 -5.251 1.00 0.00 C +ATOM 1351 C ILE 143 0.208 -5.408 -6.208 1.00 0.00 C +ATOM 1352 O ILE 143 0.440 -5.732 -7.379 1.00 0.00 O +ATOM 1353 N PHE 144 1.121 -5.448 -5.226 1.00 0.00 N +ATOM 1354 H PHE 144 0.858 -5.196 -4.313 1.00 0.00 H +ATOM 1355 CA PHE 144 2.531 -5.856 -5.397 1.00 0.00 C +ATOM 1356 CB PHE 144 3.381 -5.396 -4.190 1.00 0.00 C +ATOM 1357 CG PHE 144 3.944 -3.982 -4.316 1.00 0.00 C +ATOM 1358 CD1 PHE 144 5.294 -3.781 -4.685 1.00 0.00 C +ATOM 1359 CD2 PHE 144 3.142 -2.845 -4.049 1.00 0.00 C +ATOM 1360 CE1 PHE 144 5.839 -2.473 -4.790 1.00 0.00 C +ATOM 1361 CE2 PHE 144 3.674 -1.532 -4.149 1.00 0.00 C +ATOM 1362 CZ PHE 144 5.027 -1.346 -4.521 1.00 0.00 C +ATOM 1363 C PHE 144 2.815 -7.334 -5.706 1.00 0.00 C +ATOM 1364 O PHE 144 3.712 -7.623 -6.502 1.00 0.00 O +ATOM 1365 N ASP 145 2.042 -8.252 -5.107 1.00 0.00 N +ATOM 1366 H ASP 145 1.321 -7.968 -4.503 1.00 0.00 H +ATOM 1367 CA ASP 145 2.206 -9.711 -5.303 1.00 0.00 C +ATOM 1368 CB ASP 145 1.408 -10.516 -4.242 1.00 0.00 C +ATOM 1369 CG ASP 145 -0.078 -10.119 -4.147 1.00 0.00 C +ATOM 1370 OD1 ASP 145 -0.764 -10.005 -5.188 1.00 0.00 O +ATOM 1371 OD2 ASP 145 -0.564 -9.958 -3.009 1.00 0.00 O +ATOM 1372 C ASP 145 1.939 -10.222 -6.741 1.00 0.00 C +ATOM 1373 O ASP 145 2.203 -11.390 -7.059 1.00 0.00 O +ATOM 1374 N GLY 146 1.460 -9.312 -7.596 1.00 0.00 N +ATOM 1375 H GLY 146 1.280 -8.390 -7.309 1.00 0.00 H +ATOM 1376 CA GLY 146 1.171 -9.615 -8.991 1.00 0.00 C +ATOM 1377 C GLY 146 1.871 -8.612 -9.893 1.00 0.00 C +ATOM 1378 O GLY 146 1.255 -8.066 -10.816 1.00 0.00 O +ATOM 1379 N LEU 147 3.160 -8.384 -9.610 1.00 0.00 N +ATOM 1380 H LEU 147 3.573 -8.870 -8.864 1.00 0.00 H +ATOM 1381 CA LEU 147 4.025 -7.445 -10.341 1.00 0.00 C +ATOM 1382 CB LEU 147 4.874 -6.636 -9.334 1.00 0.00 C +ATOM 1383 CG LEU 147 5.118 -5.124 -9.488 1.00 0.00 C +ATOM 1384 CD1 LEU 147 4.731 -4.407 -8.200 1.00 0.00 C +ATOM 1385 CD2 LEU 147 6.579 -4.838 -9.850 1.00 0.00 C +ATOM 1386 C LEU 147 4.943 -8.190 -11.333 1.00 0.00 C +ATOM 1387 O LEU 147 5.104 -9.410 -11.226 1.00 0.00 O +ATOM 1388 N THR 148 5.510 -7.444 -12.294 1.00 0.00 N +ATOM 1389 H THR 148 5.328 -6.480 -12.343 1.00 0.00 H +ATOM 1390 CA THR 148 6.423 -7.971 -13.327 1.00 0.00 C +ATOM 1391 CB THR 148 5.906 -7.665 -14.768 1.00 0.00 C +ATOM 1392 OG1 THR 148 5.561 -6.277 -14.876 1.00 0.00 O +ATOM 1393 HG1 THR 148 6.337 -5.725 -14.749 1.00 0.00 H +ATOM 1394 CG2 THR 148 4.689 -8.521 -15.099 1.00 0.00 C +ATOM 1395 C THR 148 7.845 -7.399 -13.160 1.00 0.00 C +ATOM 1396 O THR 148 8.006 -6.264 -12.690 1.00 0.00 O +ATOM 1397 N ASP 149 8.855 -8.205 -13.519 1.00 0.00 N +ATOM 1398 H ASP 149 8.671 -9.105 -13.865 1.00 0.00 H +ATOM 1399 CA ASP 149 10.282 -7.838 -13.436 1.00 0.00 C +ATOM 1400 CB ASP 149 11.057 -8.884 -12.607 1.00 0.00 C +ATOM 1401 CG ASP 149 10.631 -8.915 -11.143 1.00 0.00 C +ATOM 1402 OD1 ASP 149 11.251 -8.203 -10.323 1.00 0.00 O +ATOM 1403 OD2 ASP 149 9.686 -9.663 -10.810 1.00 0.00 O +ATOM 1404 C ASP 149 10.904 -7.707 -14.839 1.00 0.00 C +ATOM 1405 O ASP 149 12.068 -7.300 -14.973 1.00 0.00 O +ATOM 1406 N LYS 150 10.100 -8.022 -15.873 1.00 0.00 N +ATOM 1407 H LYS 150 9.177 -8.306 -15.694 1.00 0.00 H +ATOM 1408 CA LYS 150 10.453 -7.992 -17.323 1.00 0.00 C +ATOM 1409 CB LYS 150 10.846 -6.573 -17.804 1.00 0.00 C +ATOM 1410 CG LYS 150 9.707 -5.561 -17.793 1.00 0.00 C +ATOM 1411 CD LYS 150 10.177 -4.193 -18.275 1.00 0.00 C +ATOM 1412 CE LYS 150 9.050 -3.161 -18.271 1.00 0.00 C +ATOM 1413 NZ LYS 150 8.589 -2.786 -16.900 1.00 0.00 N +ATOM 1414 HZ1 LYS 150 8.238 -3.633 -16.409 1.00 0.00 H +ATOM 1415 HZ2 LYS 150 7.825 -2.084 -16.971 1.00 0.00 H +ATOM 1416 HZ3 LYS 150 9.384 -2.380 -16.366 1.00 0.00 H +ATOM 1417 C LYS 150 11.513 -9.036 -17.747 1.00 0.00 C +ATOM 1418 O LYS 150 11.871 -9.130 -18.932 1.00 0.00 O +ATOM 1419 N LYS 151 11.954 -9.845 -16.773 1.00 0.00 N +ATOM 1420 H LYS 151 11.604 -9.769 -15.860 1.00 0.00 H +ATOM 1421 CA LYS 151 12.960 -10.910 -16.954 1.00 0.00 C +ATOM 1422 CB LYS 151 13.994 -10.861 -15.813 1.00 0.00 C +ATOM 1423 CG LYS 151 14.918 -9.647 -15.839 1.00 0.00 C +ATOM 1424 CD LYS 151 15.903 -9.679 -14.682 1.00 0.00 C +ATOM 1425 CE LYS 151 16.824 -8.470 -14.708 1.00 0.00 C +ATOM 1426 NZ LYS 151 17.795 -8.488 -13.579 1.00 0.00 N +ATOM 1427 HZ1 LYS 151 18.405 -7.646 -13.633 1.00 0.00 H +ATOM 1428 HZ2 LYS 151 17.278 -8.484 -12.677 1.00 0.00 H +ATOM 1429 HZ3 LYS 151 18.381 -9.345 -13.639 1.00 0.00 H +ATOM 1430 C LYS 151 12.277 -12.294 -17.018 1.00 0.00 C +ATOM 1431 O LYS 151 11.052 -12.363 -17.176 1.00 0.00 O +ATOM 1432 N THR 152 13.066 -13.375 -16.898 1.00 0.00 N +ATOM 1433 H THR 152 14.032 -13.241 -16.766 1.00 0.00 H +ATOM 1434 CA THR 152 12.584 -14.773 -16.940 1.00 0.00 C +ATOM 1435 CB THR 152 13.711 -15.747 -17.401 1.00 0.00 C +ATOM 1436 OG1 THR 152 14.900 -15.509 -16.636 1.00 0.00 O +ATOM 1437 HG1 THR 152 15.591 -16.110 -16.923 1.00 0.00 H +ATOM 1438 CG2 THR 152 14.012 -15.563 -18.885 1.00 0.00 C +ATOM 1439 C THR 152 12.003 -15.259 -15.596 1.00 0.00 C +ATOM 1440 O THR 152 11.151 -16.159 -15.569 1.00 0.00 O +ATOM 1441 N GLY 153 12.434 -14.618 -14.504 1.00 0.00 N +ATOM 1442 H GLY 153 13.080 -13.881 -14.568 1.00 0.00 H +ATOM 1443 CA GLY 153 11.977 -14.968 -13.163 1.00 0.00 C +ATOM 1444 C GLY 153 10.976 -13.993 -12.559 1.00 0.00 C +ATOM 1445 O GLY 153 11.208 -13.473 -11.461 1.00 0.00 O +ATOM 1446 N ARG 154 9.874 -13.755 -13.282 1.00 0.00 N +ATOM 1447 H ARG 154 9.770 -14.206 -14.147 1.00 0.00 H +ATOM 1448 CA ARG 154 8.789 -12.850 -12.862 1.00 0.00 C +ATOM 1449 CB ARG 154 8.472 -11.803 -13.959 1.00 0.00 C +ATOM 1450 CG ARG 154 8.319 -12.322 -15.406 1.00 0.00 C +ATOM 1451 CD ARG 154 8.011 -11.187 -16.370 1.00 0.00 C +ATOM 1452 NE ARG 154 7.862 -11.659 -17.748 1.00 0.00 N +ATOM 1453 HE ARG 154 7.968 -12.618 -17.922 1.00 0.00 H +ATOM 1454 CZ ARG 154 7.590 -10.886 -18.800 1.00 0.00 C +ATOM 1455 NH1 ARG 154 7.479 -11.434 -20.003 1.00 0.00 N +ATOM 1456 HH11 ARG 154 7.598 -12.421 -20.115 1.00 0.00 H +ATOM 1457 HH12 ARG 154 7.276 -10.861 -20.796 1.00 0.00 H +ATOM 1458 NH2 ARG 154 7.429 -9.573 -18.667 1.00 0.00 N +ATOM 1459 HH21 ARG 154 7.511 -9.148 -17.765 1.00 0.00 H +ATOM 1460 HH22 ARG 154 7.226 -9.010 -19.468 1.00 0.00 H +ATOM 1461 C ARG 154 7.506 -13.614 -12.425 1.00 0.00 C +ATOM 1462 O ARG 154 7.179 -14.629 -13.053 1.00 0.00 O +ATOM 1463 N PRO 155 6.779 -13.169 -11.344 1.00 0.00 N +ATOM 1464 CD PRO 155 5.468 -13.841 -11.201 1.00 0.00 C +ATOM 1465 CA PRO 155 6.848 -12.065 -10.356 1.00 0.00 C +ATOM 1466 CB PRO 155 5.579 -12.276 -9.526 1.00 0.00 C +ATOM 1467 CG PRO 155 4.626 -12.790 -10.514 1.00 0.00 C +ATOM 1468 C PRO 155 8.104 -11.998 -9.455 1.00 0.00 C +ATOM 1469 O PRO 155 8.980 -12.867 -9.544 1.00 0.00 O +ATOM 1470 N LEU 156 8.155 -10.975 -8.587 1.00 0.00 N +ATOM 1471 H LEU 156 7.397 -10.349 -8.549 1.00 0.00 H +ATOM 1472 CA LEU 156 9.267 -10.700 -7.654 1.00 0.00 C +ATOM 1473 CB LEU 156 9.105 -9.277 -7.051 1.00 0.00 C +ATOM 1474 CG LEU 156 7.975 -8.728 -6.144 1.00 0.00 C +ATOM 1475 CD1 LEU 156 8.424 -7.399 -5.567 1.00 0.00 C +ATOM 1476 CD2 LEU 156 6.643 -8.564 -6.868 1.00 0.00 C +ATOM 1477 C LEU 156 9.523 -11.733 -6.534 1.00 0.00 C +ATOM 1478 O LEU 156 10.679 -12.081 -6.267 1.00 0.00 O +ATOM 1479 N ILE 157 8.439 -12.206 -5.902 1.00 0.00 N +ATOM 1480 H ILE 157 7.547 -11.920 -6.190 1.00 0.00 H +ATOM 1481 CA ILE 157 8.493 -13.172 -4.790 1.00 0.00 C +ATOM 1482 CB ILE 157 7.540 -12.738 -3.581 1.00 0.00 C +ATOM 1483 CG2 ILE 157 8.153 -11.531 -2.855 1.00 0.00 C +ATOM 1484 CG1 ILE 157 6.032 -12.613 -3.975 1.00 0.00 C +ATOM 1485 CD1 ILE 157 5.561 -11.409 -4.862 1.00 0.00 C +ATOM 1486 C ILE 157 8.288 -14.656 -5.172 1.00 0.00 C +ATOM 1487 O ILE 157 7.361 -14.986 -5.926 1.00 0.00 O +ATOM 1488 N GLU 158 9.182 -15.518 -4.667 1.00 0.00 N +ATOM 1489 H GLU 158 9.913 -15.196 -4.094 1.00 0.00 H +ATOM 1490 CA GLU 158 9.165 -16.975 -4.906 1.00 0.00 C +ATOM 1491 CB GLU 158 10.363 -17.410 -5.766 1.00 0.00 C +ATOM 1492 CG GLU 158 10.337 -16.914 -7.209 1.00 0.00 C +ATOM 1493 CD GLU 158 11.542 -17.373 -8.009 1.00 0.00 C +ATOM 1494 OE1 GLU 158 11.471 -18.458 -8.625 1.00 0.00 O +ATOM 1495 OE2 GLU 158 12.559 -16.648 -8.024 1.00 0.00 O +ATOM 1496 C GLU 158 9.198 -17.736 -3.577 1.00 0.00 C +ATOM 1497 O GLU 158 8.561 -18.788 -3.447 1.00 0.00 O +ATOM 1498 N GLY 159 9.940 -17.194 -2.606 1.00 0.00 N +ATOM 1499 H GLY 159 10.430 -16.354 -2.747 1.00 0.00 H +ATOM 1500 CA GLY 159 10.069 -17.808 -1.292 1.00 0.00 C +ATOM 1501 C GLY 159 10.227 -16.774 -0.193 1.00 0.00 C +ATOM 1502 O GLY 159 10.842 -17.057 0.843 1.00 0.00 O +ATOM 1503 N LYS 160 9.668 -15.581 -0.431 1.00 0.00 N +ATOM 1504 H LYS 160 9.199 -15.438 -1.280 1.00 0.00 H +ATOM 1505 CA LYS 160 9.706 -14.447 0.507 1.00 0.00 C +ATOM 1506 CB LYS 160 10.129 -13.160 -0.214 1.00 0.00 C +ATOM 1507 CG LYS 160 11.581 -13.140 -0.682 1.00 0.00 C +ATOM 1508 CD LYS 160 11.914 -11.841 -1.397 1.00 0.00 C +ATOM 1509 CE LYS 160 13.360 -11.822 -1.863 1.00 0.00 C +ATOM 1510 NZ LYS 160 13.701 -10.554 -2.565 1.00 0.00 N +ATOM 1511 HZ1 LYS 160 13.089 -10.444 -3.398 1.00 0.00 H +ATOM 1512 HZ2 LYS 160 13.556 -9.751 -1.920 1.00 0.00 H +ATOM 1513 HZ3 LYS 160 14.696 -10.582 -2.866 1.00 0.00 H +ATOM 1514 C LYS 160 8.339 -14.246 1.182 1.00 0.00 C +ATOM 1515 O LYS 160 7.330 -14.764 0.689 1.00 0.00 O +ATOM 1516 N SER 161 8.320 -13.500 2.297 1.00 0.00 N +ATOM 1517 H SER 161 9.143 -13.090 2.636 1.00 0.00 H +ATOM 1518 CA SER 161 7.096 -13.223 3.067 1.00 0.00 C +ATOM 1519 CB SER 161 7.334 -13.474 4.560 1.00 0.00 C +ATOM 1520 OG SER 161 7.710 -14.819 4.801 1.00 0.00 O +ATOM 1521 HG SER 161 7.000 -15.419 4.557 1.00 0.00 H +ATOM 1522 C SER 161 6.516 -11.814 2.867 1.00 0.00 C +ATOM 1523 O SER 161 7.231 -10.809 2.987 1.00 0.00 O +ATOM 1524 N ILE 162 5.222 -11.776 2.519 1.00 0.00 N +ATOM 1525 H ILE 162 4.721 -12.612 2.386 1.00 0.00 H +ATOM 1526 CA ILE 162 4.427 -10.552 2.299 1.00 0.00 C +ATOM 1527 CB ILE 162 4.084 -10.342 0.766 1.00 0.00 C +ATOM 1528 CG2 ILE 162 2.869 -9.389 0.576 1.00 0.00 C +ATOM 1529 CG1 ILE 162 5.333 -9.841 0.017 1.00 0.00 C +ATOM 1530 CD1 ILE 162 5.268 -9.917 -1.517 1.00 0.00 C +ATOM 1531 C ILE 162 3.169 -10.740 3.175 1.00 0.00 C +ATOM 1532 O ILE 162 2.587 -11.832 3.197 1.00 0.00 O +ATOM 1533 N THR 163 2.778 -9.680 3.897 1.00 0.00 N +ATOM 1534 H THR 163 3.265 -8.829 3.838 1.00 0.00 H +ATOM 1535 CA THR 163 1.618 -9.701 4.808 1.00 0.00 C +ATOM 1536 CB THR 163 2.022 -9.276 6.253 1.00 0.00 C +ATOM 1537 OG1 THR 163 3.450 -9.258 6.370 1.00 0.00 O +ATOM 1538 HG1 THR 163 3.836 -10.106 6.147 1.00 0.00 H +ATOM 1539 CG2 THR 163 1.442 -10.251 7.288 1.00 0.00 C +ATOM 1540 C THR 163 0.407 -8.865 4.358 1.00 0.00 C +ATOM 1541 O THR 163 0.563 -7.784 3.782 1.00 0.00 O +ATOM 1542 N GLY 164 -0.788 -9.401 4.636 1.00 0.00 N +ATOM 1543 H GLY 164 -0.857 -10.278 5.074 1.00 0.00 H +ATOM 1544 CA GLY 164 -2.059 -8.757 4.326 1.00 0.00 C +ATOM 1545 C GLY 164 -2.875 -8.756 5.610 1.00 0.00 C +ATOM 1546 O GLY 164 -2.770 -9.717 6.381 1.00 0.00 O +ATOM 1547 N PHE 165 -3.630 -7.680 5.873 1.00 0.00 N +ATOM 1548 H PHE 165 -3.667 -6.961 5.213 1.00 0.00 H +ATOM 1549 CA PHE 165 -4.453 -7.553 7.092 1.00 0.00 C +ATOM 1550 CB PHE 165 -3.982 -6.380 7.986 1.00 0.00 C +ATOM 1551 CG PHE 165 -2.657 -6.596 8.707 1.00 0.00 C +ATOM 1552 CD1 PHE 165 -2.009 -5.488 9.276 1.00 0.00 C +ATOM 1553 CD2 PHE 165 -2.017 -7.856 8.783 1.00 0.00 C +ATOM 1554 CE1 PHE 165 -0.749 -5.610 9.897 1.00 0.00 C +ATOM 1555 CE2 PHE 165 -0.752 -7.997 9.401 1.00 0.00 C +ATOM 1556 CZ PHE 165 -0.118 -6.864 9.955 1.00 0.00 C +ATOM 1557 C PHE 165 -5.972 -7.438 6.875 1.00 0.00 C +ATOM 1558 O PHE 165 -6.480 -7.777 5.802 1.00 0.00 O +ATOM 1559 N THR 166 -6.672 -6.966 7.922 1.00 0.00 N +ATOM 1560 H THR 166 -6.194 -6.752 8.753 1.00 0.00 H +ATOM 1561 CA THR 166 -8.132 -6.756 7.991 1.00 0.00 C +ATOM 1562 CB THR 166 -8.522 -6.201 9.386 1.00 0.00 C +ATOM 1563 OG1 THR 166 -7.476 -5.360 9.886 1.00 0.00 O +ATOM 1564 HG1 THR 166 -7.724 -5.019 10.749 1.00 0.00 H +ATOM 1565 CG2 THR 166 -8.804 -7.329 10.363 1.00 0.00 C +ATOM 1566 C THR 166 -8.714 -5.859 6.877 1.00 0.00 C +ATOM 1567 O THR 166 -7.949 -5.269 6.106 1.00 0.00 O +ATOM 1568 N ASP 167 -10.058 -5.781 6.794 1.00 0.00 N +ATOM 1569 H ASP 167 -10.598 -6.268 7.454 1.00 0.00 H +ATOM 1570 CA ASP 167 -10.868 -5.024 5.793 1.00 0.00 C +ATOM 1571 CB ASP 167 -10.906 -3.480 6.048 1.00 0.00 C +ATOM 1572 CG ASP 167 -9.544 -2.792 5.903 1.00 0.00 C +ATOM 1573 OD1 ASP 167 -9.215 -2.347 4.782 1.00 0.00 O +ATOM 1574 OD2 ASP 167 -8.815 -2.689 6.913 1.00 0.00 O +ATOM 1575 C ASP 167 -10.628 -5.390 4.305 1.00 0.00 C +ATOM 1576 O ASP 167 -11.447 -5.062 3.434 1.00 0.00 O +ATOM 1577 N VAL 168 -9.516 -6.100 4.055 1.00 0.00 N +ATOM 1578 H VAL 168 -8.900 -6.374 4.754 1.00 0.00 H +ATOM 1579 CA VAL 168 -9.093 -6.585 2.731 1.00 0.00 C +ATOM 1580 CB VAL 168 -7.750 -5.847 2.220 1.00 0.00 C +ATOM 1581 CG1 VAL 168 -6.558 -6.047 3.176 1.00 0.00 C +ATOM 1582 CG2 VAL 168 -7.401 -6.239 0.775 1.00 0.00 C +ATOM 1583 C VAL 168 -8.973 -8.129 2.812 1.00 0.00 C +ATOM 1584 O VAL 168 -9.691 -8.840 2.106 1.00 0.00 O +ATOM 1585 N GLY 169 -8.158 -8.611 3.761 1.00 0.00 N +ATOM 1586 H GLY 169 -7.694 -7.993 4.360 1.00 0.00 H +ATOM 1587 CA GLY 169 -7.909 -10.036 3.969 1.00 0.00 C +ATOM 1588 C GLY 169 -9.069 -10.889 4.467 1.00 0.00 C +ATOM 1589 O GLY 169 -9.191 -12.050 4.056 1.00 0.00 O +ATOM 1590 N GLU 170 -9.905 -10.318 5.346 1.00 0.00 N +ATOM 1591 H GLU 170 -9.729 -9.392 5.618 1.00 0.00 H +ATOM 1592 CA GLU 170 -11.083 -10.992 5.935 1.00 0.00 C +ATOM 1593 CB GLU 170 -11.748 -10.113 7.020 1.00 0.00 C +ATOM 1594 CG GLU 170 -12.015 -8.635 6.664 1.00 0.00 C +ATOM 1595 CD GLU 170 -12.659 -7.867 7.802 1.00 0.00 C +ATOM 1596 OE1 GLU 170 -13.906 -7.842 7.873 1.00 0.00 O +ATOM 1597 OE2 GLU 170 -11.919 -7.289 8.625 1.00 0.00 O +ATOM 1598 C GLU 170 -12.113 -11.464 4.884 1.00 0.00 C +ATOM 1599 O GLU 170 -12.646 -12.575 4.988 1.00 0.00 O +ATOM 1600 N THR 171 -12.371 -10.599 3.891 1.00 0.00 N +ATOM 1601 H THR 171 -11.919 -9.725 3.907 1.00 0.00 H +ATOM 1602 CA THR 171 -13.286 -10.860 2.760 1.00 0.00 C +ATOM 1603 CB THR 171 -13.585 -9.557 1.954 1.00 0.00 C +ATOM 1604 OG1 THR 171 -12.358 -8.883 1.645 1.00 0.00 O +ATOM 1605 HG1 THR 171 -11.807 -9.427 1.076 1.00 0.00 H +ATOM 1606 CG2 THR 171 -14.493 -8.626 2.748 1.00 0.00 C +ATOM 1607 C THR 171 -12.672 -11.924 1.822 1.00 0.00 C +ATOM 1608 O THR 171 -13.383 -12.780 1.287 1.00 0.00 O +ATOM 1609 N ILE 172 -11.341 -11.847 1.672 1.00 0.00 N +ATOM 1610 H ILE 172 -10.864 -11.146 2.172 1.00 0.00 H +ATOM 1611 CA ILE 172 -10.496 -12.728 0.835 1.00 0.00 C +ATOM 1612 CB ILE 172 -9.122 -12.009 0.499 1.00 0.00 C +ATOM 1613 CG2 ILE 172 -8.107 -12.975 -0.192 1.00 0.00 C +ATOM 1614 CG1 ILE 172 -9.423 -10.825 -0.444 1.00 0.00 C +ATOM 1615 CD1 ILE 172 -8.443 -9.648 -0.436 1.00 0.00 C +ATOM 1616 C ILE 172 -10.343 -14.193 1.326 1.00 0.00 C +ATOM 1617 O ILE 172 -10.265 -15.110 0.496 1.00 0.00 O +ATOM 1618 N LEU 173 -10.329 -14.397 2.654 1.00 0.00 N +ATOM 1619 H LEU 173 -10.418 -13.623 3.256 1.00 0.00 H +ATOM 1620 CA LEU 173 -10.177 -15.727 3.296 1.00 0.00 C +ATOM 1621 CB LEU 173 -10.173 -15.580 4.841 1.00 0.00 C +ATOM 1622 CG LEU 173 -9.578 -16.595 5.854 1.00 0.00 C +ATOM 1623 CD1 LEU 173 -9.242 -15.864 7.137 1.00 0.00 C +ATOM 1624 CD2 LEU 173 -10.514 -17.780 6.162 1.00 0.00 C +ATOM 1625 C LEU 173 -11.266 -16.732 2.858 1.00 0.00 C +ATOM 1626 O LEU 173 -10.980 -17.924 2.704 1.00 0.00 O +ATOM 1627 N GLY 174 -12.493 -16.236 2.667 1.00 0.00 N +ATOM 1628 H GLY 174 -12.682 -15.283 2.809 1.00 0.00 H +ATOM 1629 CA GLY 174 -13.610 -17.072 2.240 1.00 0.00 C +ATOM 1630 C GLY 174 -13.980 -16.819 0.787 1.00 0.00 C +ATOM 1631 O GLY 174 -14.413 -17.741 0.087 1.00 0.00 O +ATOM 1632 N VAL 175 -13.775 -15.564 0.355 1.00 0.00 N +ATOM 1633 H VAL 175 -13.411 -14.917 0.997 1.00 0.00 H +ATOM 1634 CA VAL 175 -14.032 -15.011 -1.001 1.00 0.00 C +ATOM 1635 CB VAL 175 -12.663 -14.821 -1.827 1.00 0.00 C +ATOM 1636 CG1 VAL 175 -12.005 -16.171 -2.167 1.00 0.00 C +ATOM 1637 CG2 VAL 175 -12.864 -13.944 -3.073 1.00 0.00 C +ATOM 1638 C VAL 175 -15.206 -15.583 -1.855 1.00 0.00 C +ATOM 1639 O VAL 175 -16.172 -14.859 -2.121 1.00 0.00 O +ATOM 1640 N ASP 176 -15.107 -16.856 -2.265 1.00 0.00 N +ATOM 1641 H ASP 176 -14.319 -17.384 -2.008 1.00 0.00 H +ATOM 1642 CA ASP 176 -16.126 -17.535 -3.092 1.00 0.00 C +ATOM 1643 CB ASP 176 -15.557 -18.837 -3.685 1.00 0.00 C +ATOM 1644 CG ASP 176 -14.425 -18.593 -4.679 1.00 0.00 C +ATOM 1645 OD1 ASP 176 -13.249 -18.559 -4.254 1.00 0.00 O +ATOM 1646 OD2 ASP 176 -14.709 -18.452 -5.889 1.00 0.00 O +ATOM 1647 C ASP 176 -17.474 -17.822 -2.399 1.00 0.00 C +ATOM 1648 O ASP 176 -18.527 -17.534 -2.977 1.00 0.00 O +ATOM 1649 N SER 177 -17.431 -18.395 -1.186 1.00 0.00 N +ATOM 1650 H SER 177 -16.560 -18.612 -0.784 1.00 0.00 H +ATOM 1651 CA SER 177 -18.631 -18.726 -0.389 1.00 0.00 C +ATOM 1652 CB SER 177 -18.274 -19.752 0.698 1.00 0.00 C +ATOM 1653 OG SER 177 -19.430 -20.268 1.339 1.00 0.00 O +ATOM 1654 HG SER 177 -19.168 -20.904 2.009 1.00 0.00 H +ATOM 1655 C SER 177 -19.361 -17.511 0.233 1.00 0.00 C +ATOM 1656 O SER 177 -20.583 -17.387 0.092 1.00 0.00 O +ATOM 1657 N ILE 178 -18.597 -16.639 0.909 1.00 0.00 N +ATOM 1658 H ILE 178 -17.630 -16.805 0.967 1.00 0.00 H +ATOM 1659 CA ILE 178 -19.100 -15.417 1.580 1.00 0.00 C +ATOM 1660 CB ILE 178 -18.152 -14.939 2.752 1.00 0.00 C +ATOM 1661 CG2 ILE 178 -18.334 -15.871 3.963 1.00 0.00 C +ATOM 1662 CG1 ILE 178 -16.675 -14.847 2.303 1.00 0.00 C +ATOM 1663 CD1 ILE 178 -15.843 -13.769 3.014 1.00 0.00 C +ATOM 1664 C ILE 178 -19.545 -14.217 0.706 1.00 0.00 C +ATOM 1665 O ILE 178 -20.617 -13.645 0.941 1.00 0.00 O +ATOM 1666 N LEU 179 -18.722 -13.871 -0.295 1.00 0.00 N +ATOM 1667 H LEU 179 -17.898 -14.381 -0.456 1.00 0.00 H +ATOM 1668 CA LEU 179 -18.963 -12.740 -1.213 1.00 0.00 C +ATOM 1669 CB LEU 179 -17.632 -12.035 -1.562 1.00 0.00 C +ATOM 1670 CG LEU 179 -16.767 -11.307 -0.512 1.00 0.00 C +ATOM 1671 CD1 LEU 179 -15.314 -11.385 -0.946 1.00 0.00 C +ATOM 1672 CD2 LEU 179 -17.185 -9.839 -0.296 1.00 0.00 C +ATOM 1673 C LEU 179 -19.716 -13.104 -2.502 1.00 0.00 C +ATOM 1674 O LEU 179 -20.578 -12.338 -2.945 1.00 0.00 O +ATOM 1675 N LYS 180 -19.396 -14.278 -3.077 1.00 0.00 N +ATOM 1676 H LYS 180 -18.712 -14.846 -2.658 1.00 0.00 H +ATOM 1677 CA LYS 180 -19.982 -14.845 -4.326 1.00 0.00 C +ATOM 1678 CB LYS 180 -21.436 -15.334 -4.120 1.00 0.00 C +ATOM 1679 CG LYS 180 -21.585 -16.524 -3.180 1.00 0.00 C +ATOM 1680 CD LYS 180 -23.042 -16.935 -3.037 1.00 0.00 C +ATOM 1681 CE LYS 180 -23.192 -18.122 -2.100 1.00 0.00 C +ATOM 1682 NZ LYS 180 -24.614 -18.536 -1.950 1.00 0.00 N +ATOM 1683 HZ1 LYS 180 -24.673 -19.348 -1.304 1.00 0.00 H +ATOM 1684 HZ2 LYS 180 -25.166 -17.744 -1.564 1.00 0.00 H +ATOM 1685 HZ3 LYS 180 -24.997 -18.804 -2.880 1.00 0.00 H +ATOM 1686 C LYS 180 -19.886 -13.968 -5.596 1.00 0.00 C +ATOM 1687 O LYS 180 -19.240 -14.370 -6.572 1.00 0.00 O +ATOM 1688 N ALA 181 -20.527 -12.791 -5.566 1.00 0.00 N +ATOM 1689 H ALA 181 -21.047 -12.527 -4.779 1.00 0.00 H +ATOM 1690 CA ALA 181 -20.549 -11.824 -6.677 1.00 0.00 C +ATOM 1691 CB ALA 181 -22.004 -11.545 -7.099 1.00 0.00 C +ATOM 1692 C ALA 181 -19.834 -10.521 -6.268 1.00 0.00 C +ATOM 1693 O ALA 181 -19.022 -10.539 -5.335 1.00 0.00 O +ATOM 1694 N LYS 182 -20.130 -9.411 -6.972 1.00 0.00 N +ATOM 1695 H LYS 182 -20.772 -9.469 -7.713 1.00 0.00 H +ATOM 1696 CA LYS 182 -19.573 -8.044 -6.762 1.00 0.00 C +ATOM 1697 CB LYS 182 -19.946 -7.470 -5.375 1.00 0.00 C +ATOM 1698 CG LYS 182 -21.441 -7.235 -5.175 1.00 0.00 C +ATOM 1699 CD LYS 182 -21.745 -6.720 -3.780 1.00 0.00 C +ATOM 1700 CE LYS 182 -23.238 -6.514 -3.580 1.00 0.00 C +ATOM 1701 NZ LYS 182 -23.551 -6.008 -2.215 1.00 0.00 N +ATOM 1702 HZ1 LYS 182 -23.219 -6.694 -1.507 1.00 0.00 H +ATOM 1703 HZ2 LYS 182 -24.578 -5.881 -2.120 1.00 0.00 H +ATOM 1704 HZ3 LYS 182 -23.073 -5.097 -2.065 1.00 0.00 H +ATOM 1705 C LYS 182 -18.060 -7.887 -7.032 1.00 0.00 C +ATOM 1706 O LYS 182 -17.329 -8.886 -7.055 1.00 0.00 O +ATOM 1707 N ASN 183 -17.614 -6.638 -7.233 1.00 0.00 N +ATOM 1708 H ASN 183 -18.238 -5.880 -7.189 1.00 0.00 H +ATOM 1709 CA ASN 183 -16.208 -6.287 -7.526 1.00 0.00 C +ATOM 1710 CB ASN 183 -16.139 -5.006 -8.396 1.00 0.00 C +ATOM 1711 CG ASN 183 -16.975 -3.847 -7.840 1.00 0.00 C +ATOM 1712 OD1 ASN 183 -16.482 -3.028 -7.062 1.00 0.00 O +ATOM 1713 ND2 ASN 183 -18.237 -3.773 -8.252 1.00 0.00 N +ATOM 1714 HD21 ASN 183 -18.786 -3.038 -7.907 1.00 0.00 H +ATOM 1715 HD22 ASN 183 -18.575 -4.446 -8.880 1.00 0.00 H +ATOM 1716 C ASN 183 -15.240 -6.204 -6.318 1.00 0.00 C +ATOM 1717 O ASN 183 -15.269 -5.231 -5.550 1.00 0.00 O +ATOM 1718 N LEU 184 -14.439 -7.267 -6.140 1.00 0.00 N +ATOM 1719 H LEU 184 -14.500 -8.037 -6.746 1.00 0.00 H +ATOM 1720 CA LEU 184 -13.429 -7.394 -5.067 1.00 0.00 C +ATOM 1721 CB LEU 184 -13.996 -8.154 -3.830 1.00 0.00 C +ATOM 1722 CG LEU 184 -15.187 -7.833 -2.880 1.00 0.00 C +ATOM 1723 CD1 LEU 184 -15.057 -6.466 -2.183 1.00 0.00 C +ATOM 1724 CD2 LEU 184 -16.558 -7.981 -3.558 1.00 0.00 C +ATOM 1725 C LEU 184 -12.201 -8.145 -5.610 1.00 0.00 C +ATOM 1726 O LEU 184 -12.339 -8.974 -6.518 1.00 0.00 O +ATOM 1727 N ALA 185 -11.018 -7.848 -5.050 1.00 0.00 N +ATOM 1728 H ALA 185 -10.966 -7.179 -4.333 1.00 0.00 H +ATOM 1729 CA ALA 185 -9.735 -8.468 -5.439 1.00 0.00 C +ATOM 1730 CB ALA 185 -8.662 -7.395 -5.595 1.00 0.00 C +ATOM 1731 C ALA 185 -9.294 -9.518 -4.404 1.00 0.00 C +ATOM 1732 O ALA 185 -9.794 -9.503 -3.276 1.00 0.00 O +ATOM 1733 N THR 186 -8.386 -10.424 -4.802 1.00 0.00 N +ATOM 1734 H THR 186 -8.028 -10.395 -5.716 1.00 0.00 H +ATOM 1735 CA THR 186 -7.862 -11.506 -3.937 1.00 0.00 C +ATOM 1736 CB THR 186 -8.147 -12.926 -4.540 1.00 0.00 C +ATOM 1737 OG1 THR 186 -7.655 -12.989 -5.886 1.00 0.00 O +ATOM 1738 HG1 THR 186 -8.121 -12.361 -6.444 1.00 0.00 H +ATOM 1739 CG2 THR 186 -9.636 -13.230 -4.533 1.00 0.00 C +ATOM 1740 C THR 186 -6.355 -11.376 -3.612 1.00 0.00 C +ATOM 1741 O THR 186 -5.508 -11.481 -4.509 1.00 0.00 O +ATOM 1742 N VAL 187 -6.046 -11.055 -2.346 1.00 0.00 N +ATOM 1743 H VAL 187 -6.777 -10.931 -1.704 1.00 0.00 H +ATOM 1744 CA VAL 187 -4.667 -10.902 -1.826 1.00 0.00 C +ATOM 1745 CB VAL 187 -4.674 -10.024 -0.476 1.00 0.00 C +ATOM 1746 CG1 VAL 187 -5.303 -10.778 0.713 1.00 0.00 C +ATOM 1747 CG2 VAL 187 -3.282 -9.505 -0.120 1.00 0.00 C +ATOM 1748 C VAL 187 -3.914 -12.261 -1.670 1.00 0.00 C +ATOM 1749 O VAL 187 -2.799 -12.425 -2.187 1.00 0.00 O +ATOM 1750 N GLU 188 -4.598 -13.230 -1.041 1.00 0.00 N +ATOM 1751 H GLU 188 -5.520 -13.047 -0.752 1.00 0.00 H +ATOM 1752 CA GLU 188 -4.087 -14.580 -0.741 1.00 0.00 C +ATOM 1753 CB GLU 188 -5.002 -15.267 0.294 1.00 0.00 C +ATOM 1754 CG GLU 188 -4.319 -16.301 1.208 1.00 0.00 C +ATOM 1755 CD GLU 188 -5.301 -17.074 2.070 1.00 0.00 C +ATOM 1756 OE1 GLU 188 -5.913 -18.041 1.565 1.00 0.00 O +ATOM 1757 OE2 GLU 188 -5.454 -16.724 3.259 1.00 0.00 O +ATOM 1758 C GLU 188 -3.864 -15.488 -1.968 1.00 0.00 C +ATOM 1759 O GLU 188 -2.839 -16.170 -2.039 1.00 0.00 O +ATOM 1760 N ASP 189 -4.798 -15.459 -2.928 1.00 0.00 N +ATOM 1761 H ASP 189 -5.572 -14.860 -2.827 1.00 0.00 H +ATOM 1762 CA ASP 189 -4.744 -16.276 -4.158 1.00 0.00 C +ATOM 1763 CB ASP 189 -6.097 -16.209 -4.894 1.00 0.00 C +ATOM 1764 CG ASP 189 -6.463 -17.518 -5.598 1.00 0.00 C +ATOM 1765 OD1 ASP 189 -6.131 -17.667 -6.793 1.00 0.00 O +ATOM 1766 OD2 ASP 189 -7.098 -18.386 -4.959 1.00 0.00 O +ATOM 1767 C ASP 189 -3.589 -15.864 -5.099 1.00 0.00 C +ATOM 1768 O ASP 189 -2.841 -16.731 -5.571 1.00 0.00 O +ATOM 1769 N VAL 190 -3.418 -14.547 -5.300 1.00 0.00 N +ATOM 1770 H VAL 190 -4.016 -13.914 -4.842 1.00 0.00 H +ATOM 1771 CA VAL 190 -2.367 -13.977 -6.172 1.00 0.00 C +ATOM 1772 CB VAL 190 -2.622 -12.448 -6.496 1.00 0.00 C +ATOM 1773 CG1 VAL 190 -1.615 -11.916 -7.537 1.00 0.00 C +ATOM 1774 CG2 VAL 190 -4.031 -12.254 -7.052 1.00 0.00 C +ATOM 1775 C VAL 190 -0.953 -14.212 -5.589 1.00 0.00 C +ATOM 1776 O VAL 190 -0.040 -14.581 -6.335 1.00 0.00 O +ATOM 1777 N ALA 191 -0.787 -13.996 -4.276 1.00 0.00 N +ATOM 1778 H ALA 191 -1.542 -13.676 -3.724 1.00 0.00 H +ATOM 1779 CA ALA 191 0.495 -14.193 -3.571 1.00 0.00 C +ATOM 1780 CB ALA 191 0.466 -13.511 -2.232 1.00 0.00 C +ATOM 1781 C ALA 191 0.938 -15.661 -3.418 1.00 0.00 C +ATOM 1782 O ALA 191 2.121 -15.971 -3.597 1.00 0.00 O +ATOM 1783 N LYS 192 -0.018 -16.541 -3.085 1.00 0.00 N +ATOM 1784 H LYS 192 -0.940 -16.226 -2.951 1.00 0.00 H +ATOM 1785 CA LYS 192 0.199 -17.992 -2.898 1.00 0.00 C +ATOM 1786 CB LYS 192 -0.983 -18.645 -2.173 1.00 0.00 C +ATOM 1787 CG LYS 192 -0.920 -18.518 -0.658 1.00 0.00 C +ATOM 1788 CD LYS 192 -2.055 -19.281 0.018 1.00 0.00 C +ATOM 1789 CE LYS 192 -1.821 -19.449 1.520 1.00 0.00 C +ATOM 1790 NZ LYS 192 -1.857 -18.174 2.296 1.00 0.00 N +ATOM 1791 HZ1 LYS 192 -1.139 -17.518 1.927 1.00 0.00 H +ATOM 1792 HZ2 LYS 192 -1.661 -18.376 3.297 1.00 0.00 H +ATOM 1793 HZ3 LYS 192 -2.798 -17.748 2.214 1.00 0.00 H +ATOM 1794 C LYS 192 0.548 -18.779 -4.173 1.00 0.00 C +ATOM 1795 O LYS 192 1.318 -19.745 -4.106 1.00 0.00 O +ATOM 1796 N LYS 193 -0.015 -18.359 -5.317 1.00 0.00 N +ATOM 1797 H LYS 193 -0.640 -17.591 -5.301 1.00 0.00 H +ATOM 1798 CA LYS 193 0.204 -18.997 -6.634 1.00 0.00 C +ATOM 1799 CB LYS 193 -0.642 -18.317 -7.717 1.00 0.00 C +ATOM 1800 CG LYS 193 -2.064 -18.844 -7.823 1.00 0.00 C +ATOM 1801 CD LYS 193 -2.810 -18.184 -8.972 1.00 0.00 C +ATOM 1802 CE LYS 193 -4.200 -18.772 -9.140 1.00 0.00 C +ATOM 1803 NZ LYS 193 -4.942 -18.134 -10.263 1.00 0.00 N +ATOM 1804 HZ1 LYS 193 -5.040 -17.115 -10.078 1.00 0.00 H +ATOM 1805 HZ2 LYS 193 -5.885 -18.563 -10.344 1.00 0.00 H +ATOM 1806 HZ3 LYS 193 -4.418 -18.277 -11.150 1.00 0.00 H +ATOM 1807 C LYS 193 1.671 -19.070 -7.100 1.00 0.00 C +ATOM 1808 O LYS 193 2.062 -20.066 -7.722 1.00 0.00 O +ATOM 1809 N TYR 194 2.468 -18.033 -6.795 1.00 0.00 N +ATOM 1810 H TYR 194 2.114 -17.260 -6.304 1.00 0.00 H +ATOM 1811 CA TYR 194 3.894 -17.986 -7.171 1.00 0.00 C +ATOM 1812 CB TYR 194 4.244 -16.665 -7.912 1.00 0.00 C +ATOM 1813 CG TYR 194 5.359 -16.760 -8.968 1.00 0.00 C +ATOM 1814 CD1 TYR 194 6.658 -16.266 -8.702 1.00 0.00 C +ATOM 1815 CE1 TYR 194 7.694 -16.346 -9.676 1.00 0.00 C +ATOM 1816 CD2 TYR 194 5.121 -17.339 -10.243 1.00 0.00 C +ATOM 1817 CE2 TYR 194 6.151 -17.425 -11.221 1.00 0.00 C +ATOM 1818 CZ TYR 194 7.430 -16.926 -10.927 1.00 0.00 C +ATOM 1819 OH TYR 194 8.431 -17.005 -11.868 1.00 0.00 O +ATOM 1820 HH TYR 194 8.105 -17.423 -12.668 1.00 0.00 H +ATOM 1821 C TYR 194 4.844 -18.232 -5.983 1.00 0.00 C +ATOM 1822 O TYR 194 5.726 -19.092 -6.081 1.00 0.00 O +ATOM 1823 N GLY 195 4.666 -17.490 -4.884 1.00 0.00 N +ATOM 1824 H GLY 195 3.961 -16.809 -4.837 1.00 0.00 H +ATOM 1825 CA GLY 195 5.519 -17.673 -3.715 1.00 0.00 C +ATOM 1826 C GLY 195 5.572 -16.565 -2.676 1.00 0.00 C +ATOM 1827 O GLY 195 6.555 -15.816 -2.627 1.00 0.00 O +ATOM 1828 N ALA 196 4.517 -16.467 -1.855 1.00 0.00 N +ATOM 1829 H ALA 196 3.769 -17.089 -1.979 1.00 0.00 H +ATOM 1830 CA ALA 196 4.390 -15.481 -0.763 1.00 0.00 C +ATOM 1831 CB ALA 196 3.911 -14.118 -1.288 1.00 0.00 C +ATOM 1832 C ALA 196 3.417 -16.021 0.295 1.00 0.00 C +ATOM 1833 O ALA 196 2.354 -16.551 -0.053 1.00 0.00 O +ATOM 1834 N LYS 197 3.799 -15.891 1.574 1.00 0.00 N +ATOM 1835 H LYS 197 4.652 -15.455 1.795 1.00 0.00 H +ATOM 1836 CA LYS 197 3.012 -16.367 2.730 1.00 0.00 C +ATOM 1837 CB LYS 197 3.816 -17.401 3.536 1.00 0.00 C +ATOM 1838 CG LYS 197 4.034 -18.734 2.827 1.00 0.00 C +ATOM 1839 CD LYS 197 4.837 -19.698 3.694 1.00 0.00 C +ATOM 1840 CE LYS 197 5.068 -21.040 3.003 1.00 0.00 C +ATOM 1841 NZ LYS 197 5.988 -20.957 1.829 1.00 0.00 N +ATOM 1842 HZ1 LYS 197 6.099 -21.902 1.409 1.00 0.00 H +ATOM 1843 HZ2 LYS 197 5.588 -20.308 1.121 1.00 0.00 H +ATOM 1844 HZ3 LYS 197 6.915 -20.604 2.139 1.00 0.00 H +ATOM 1845 C LYS 197 2.558 -15.236 3.666 1.00 0.00 C +ATOM 1846 O LYS 197 3.294 -14.262 3.858 1.00 0.00 O +ATOM 1847 N TYR 198 1.339 -15.370 4.215 1.00 0.00 N +ATOM 1848 H TYR 198 0.782 -16.149 3.996 1.00 0.00 H +ATOM 1849 CA TYR 198 0.734 -14.404 5.159 1.00 0.00 C +ATOM 1850 CB TYR 198 -0.687 -13.975 4.689 1.00 0.00 C +ATOM 1851 CG TYR 198 -0.776 -13.339 3.307 1.00 0.00 C +ATOM 1852 CD1 TYR 198 -0.799 -11.940 3.160 1.00 0.00 C +ATOM 1853 CE1 TYR 198 -0.886 -11.329 1.891 1.00 0.00 C +ATOM 1854 CD2 TYR 198 -0.849 -14.128 2.137 1.00 0.00 C +ATOM 1855 CE2 TYR 198 -0.937 -13.528 0.863 1.00 0.00 C +ATOM 1856 CZ TYR 198 -0.953 -12.128 0.749 1.00 0.00 C +ATOM 1857 OH TYR 198 -1.021 -11.532 -0.487 1.00 0.00 O +ATOM 1858 HH TYR 198 -1.020 -10.576 -0.403 1.00 0.00 H +ATOM 1859 C TYR 198 0.667 -15.051 6.557 1.00 0.00 C +ATOM 1860 O TYR 198 0.389 -16.252 6.669 1.00 0.00 O +ATOM 1861 N LEU 199 0.932 -14.252 7.601 1.00 0.00 N +ATOM 1862 H LEU 199 1.136 -13.302 7.458 1.00 0.00 H +ATOM 1863 CA LEU 199 0.941 -14.703 9.008 1.00 0.00 C +ATOM 1864 CB LEU 199 2.271 -14.276 9.676 1.00 0.00 C +ATOM 1865 CG LEU 199 3.017 -15.230 10.636 1.00 0.00 C +ATOM 1866 CD1 LEU 199 4.214 -15.910 9.952 1.00 0.00 C +ATOM 1867 CD2 LEU 199 3.494 -14.448 11.851 1.00 0.00 C +ATOM 1868 C LEU 199 -0.263 -14.132 9.791 1.00 0.00 C +ATOM 1869 O LEU 199 -0.427 -14.413 10.988 1.00 0.00 O +ATOM 1870 N ALA 200 -1.121 -13.395 9.079 1.00 0.00 N +ATOM 1871 H ALA 200 -0.979 -13.258 8.116 1.00 0.00 H +ATOM 1872 CA ALA 200 -2.315 -12.742 9.634 1.00 0.00 C +ATOM 1873 CB ALA 200 -2.438 -11.355 9.041 1.00 0.00 C +ATOM 1874 C ALA 200 -3.683 -13.479 9.542 1.00 0.00 C +ATOM 1875 O ALA 200 -4.542 -13.219 10.392 1.00 0.00 O +ATOM 1876 N PRO 201 -3.897 -14.422 8.564 1.00 0.00 N +ATOM 1877 CD PRO 201 -2.965 -14.838 7.490 1.00 0.00 C +ATOM 1878 CA PRO 201 -5.164 -15.169 8.388 1.00 0.00 C +ATOM 1879 CB PRO 201 -4.797 -16.183 7.309 1.00 0.00 C +ATOM 1880 CG PRO 201 -3.882 -15.432 6.462 1.00 0.00 C +ATOM 1881 C PRO 201 -5.914 -15.817 9.588 1.00 0.00 C +ATOM 1882 O PRO 201 -5.669 -15.450 10.742 1.00 0.00 O +ATOM 1883 N VAL 202 -6.830 -16.765 9.293 1.00 0.00 N +ATOM 1884 H VAL 202 -6.959 -17.026 8.355 1.00 0.00 H +ATOM 1885 CA VAL 202 -7.721 -17.503 10.240 1.00 0.00 C +ATOM 1886 CB VAL 202 -6.972 -18.682 11.075 1.00 0.00 C +ATOM 1887 CG1 VAL 202 -6.016 -18.149 12.160 1.00 0.00 C +ATOM 1888 CG2 VAL 202 -7.981 -19.683 11.655 1.00 0.00 C +ATOM 1889 C VAL 202 -8.632 -16.527 11.049 1.00 0.00 C +ATOM 1890 O VAL 202 -8.333 -16.151 12.191 1.00 0.00 O +ATOM 1891 N GLY 203 -9.714 -16.097 10.384 1.00 0.00 N +ATOM 1892 H GLY 203 -9.917 -16.425 9.482 1.00 0.00 H +ATOM 1893 CA GLY 203 -10.668 -15.135 10.935 1.00 0.00 C +ATOM 1894 C GLY 203 -10.230 -13.757 10.431 1.00 0.00 C +ATOM 1895 O GLY 203 -9.420 -13.752 9.494 1.00 0.00 O +ATOM 1896 N PRO 204 -10.720 -12.590 10.953 1.00 0.00 N +ATOM 1897 CD PRO 204 -11.870 -12.314 11.845 1.00 0.00 C +ATOM 1898 CA PRO 204 -10.196 -11.331 10.376 1.00 0.00 C +ATOM 1899 CB PRO 204 -11.105 -10.251 10.975 1.00 0.00 C +ATOM 1900 CG PRO 204 -11.634 -10.886 12.259 1.00 0.00 C +ATOM 1901 C PRO 204 -8.692 -11.106 10.680 1.00 0.00 C +ATOM 1902 O PRO 204 -8.271 -11.128 11.845 1.00 0.00 O +ATOM 1903 N TRP 205 -7.915 -10.932 9.608 1.00 0.00 N +ATOM 1904 H TRP 205 -8.341 -10.881 8.725 1.00 0.00 H +ATOM 1905 CA TRP 205 -6.453 -10.755 9.640 1.00 0.00 C +ATOM 1906 CB TRP 205 -5.899 -10.761 8.192 1.00 0.00 C +ATOM 1907 CG TRP 205 -6.402 -11.849 7.175 1.00 0.00 C +ATOM 1908 CD2 TRP 205 -5.729 -12.283 5.972 1.00 0.00 C +ATOM 1909 CE2 TRP 205 -6.582 -13.224 5.329 1.00 0.00 C +ATOM 1910 CE3 TRP 205 -4.490 -11.966 5.369 1.00 0.00 C +ATOM 1911 CD1 TRP 205 -7.598 -12.543 7.198 1.00 0.00 C +ATOM 1912 NE1 TRP 205 -7.705 -13.355 6.099 1.00 0.00 N +ATOM 1913 HE1 TRP 205 -8.478 -13.911 5.879 1.00 0.00 H +ATOM 1914 CZ2 TRP 205 -6.239 -13.855 4.109 1.00 0.00 C +ATOM 1915 CZ3 TRP 205 -4.145 -12.596 4.148 1.00 0.00 C +ATOM 1916 CH2 TRP 205 -5.024 -13.530 3.536 1.00 0.00 C +ATOM 1917 C TRP 205 -5.978 -9.504 10.424 1.00 0.00 C +ATOM 1918 O TRP 205 -5.920 -8.399 9.877 1.00 0.00 O +ATOM 1919 N ASP 206 -5.667 -9.697 11.715 1.00 0.00 N +ATOM 1920 H ASP 206 -5.735 -10.594 12.109 1.00 0.00 H +ATOM 1921 CA ASP 206 -5.210 -8.625 12.627 1.00 0.00 C +ATOM 1922 CB ASP 206 -5.573 -8.971 14.096 1.00 0.00 C +ATOM 1923 CG ASP 206 -5.120 -10.374 14.523 1.00 0.00 C +ATOM 1924 OD1 ASP 206 -4.021 -10.491 15.106 1.00 0.00 O +ATOM 1925 OD2 ASP 206 -5.871 -11.347 14.292 1.00 0.00 O +ATOM 1926 C ASP 206 -3.717 -8.243 12.468 1.00 0.00 C +ATOM 1927 O ASP 206 -3.047 -8.776 11.575 1.00 0.00 O +ATOM 1928 N ASP 207 -3.216 -7.336 13.324 1.00 0.00 N +ATOM 1929 H ASP 207 -3.808 -6.960 14.014 1.00 0.00 H +ATOM 1930 CA ASP 207 -1.817 -6.850 13.312 1.00 0.00 C +ATOM 1931 CB ASP 207 -1.643 -5.714 14.338 1.00 0.00 C +ATOM 1932 CG ASP 207 -0.365 -4.894 14.124 1.00 0.00 C +ATOM 1933 OD1 ASP 207 0.679 -5.247 14.715 1.00 0.00 O +ATOM 1934 OD2 ASP 207 -0.411 -3.892 13.378 1.00 0.00 O +ATOM 1935 C ASP 207 -0.802 -7.996 13.546 1.00 0.00 C +ATOM 1936 O ASP 207 -0.909 -8.746 14.527 1.00 0.00 O +ATOM 1937 N TYR 208 0.153 -8.113 12.613 1.00 0.00 N +ATOM 1938 H TYR 208 0.232 -7.439 11.923 1.00 0.00 H +ATOM 1939 CA TYR 208 1.198 -9.151 12.583 1.00 0.00 C +ATOM 1940 CB TYR 208 0.655 -10.407 11.845 1.00 0.00 C +ATOM 1941 CG TYR 208 -0.007 -11.479 12.722 1.00 0.00 C +ATOM 1942 CD1 TYR 208 -1.394 -11.442 13.010 1.00 0.00 C +ATOM 1943 CE1 TYR 208 -2.013 -12.458 13.791 1.00 0.00 C +ATOM 1944 CD2 TYR 208 0.746 -12.563 13.239 1.00 0.00 C +ATOM 1945 CE2 TYR 208 0.135 -13.581 14.022 1.00 0.00 C +ATOM 1946 CZ TYR 208 -1.241 -13.519 14.290 1.00 0.00 C +ATOM 1947 OH TYR 208 -1.834 -14.504 15.047 1.00 0.00 O +ATOM 1948 HH TYR 208 -2.773 -14.329 15.146 1.00 0.00 H +ATOM 1949 C TYR 208 2.502 -8.696 11.897 1.00 0.00 C +ATOM 1950 O TYR 208 3.525 -8.512 12.565 1.00 0.00 O +ATOM 1951 N SER 209 2.436 -8.519 10.563 1.00 0.00 N +ATOM 1952 H SER 209 1.576 -8.658 10.109 1.00 0.00 H +ATOM 1953 CA SER 209 3.531 -8.123 9.637 1.00 0.00 C +ATOM 1954 CB SER 209 3.922 -6.642 9.810 1.00 0.00 C +ATOM 1955 OG SER 209 4.898 -6.236 8.863 1.00 0.00 O +ATOM 1956 HG SER 209 5.709 -6.737 8.981 1.00 0.00 H +ATOM 1957 C SER 209 4.772 -9.045 9.659 1.00 0.00 C +ATOM 1958 O SER 209 5.372 -9.269 10.718 1.00 0.00 O +ATOM 1959 N ILE 210 5.116 -9.583 8.478 1.00 0.00 N +ATOM 1960 H ILE 210 4.612 -9.367 7.674 1.00 0.00 H +ATOM 1961 CA ILE 210 6.259 -10.500 8.265 1.00 0.00 C +ATOM 1962 CB ILE 210 5.817 -12.018 8.167 1.00 0.00 C +ATOM 1963 CG2 ILE 210 5.666 -12.578 9.589 1.00 0.00 C +ATOM 1964 CG1 ILE 210 4.543 -12.205 7.310 1.00 0.00 C +ATOM 1965 CD1 ILE 210 4.350 -13.603 6.706 1.00 0.00 C +ATOM 1966 C ILE 210 7.196 -10.160 7.089 1.00 0.00 C +ATOM 1967 O ILE 210 6.730 -9.719 6.031 1.00 0.00 O +ATOM 1968 N THR 211 8.509 -10.331 7.309 1.00 0.00 N +ATOM 1969 H THR 211 8.828 -10.627 8.190 1.00 0.00 H +ATOM 1970 CA THR 211 9.564 -10.101 6.299 1.00 0.00 C +ATOM 1971 CB THR 211 10.422 -8.828 6.599 1.00 0.00 C +ATOM 1972 OG1 THR 211 10.942 -8.892 7.934 1.00 0.00 O +ATOM 1973 HG1 THR 211 11.534 -9.643 8.029 1.00 0.00 H +ATOM 1974 CG2 THR 211 9.592 -7.572 6.441 1.00 0.00 C +ATOM 1975 C THR 211 10.482 -11.337 6.232 1.00 0.00 C +ATOM 1976 O THR 211 10.796 -11.930 7.275 1.00 0.00 O +ATOM 1977 N ASP 212 10.857 -11.745 5.011 1.00 0.00 N +ATOM 1978 H ASP 212 10.546 -11.268 4.211 1.00 0.00 H +ATOM 1979 CA ASP 212 11.740 -12.904 4.770 1.00 0.00 C +ATOM 1980 CB ASP 212 10.952 -14.068 4.127 1.00 0.00 C +ATOM 1981 CG ASP 212 11.536 -15.444 4.458 1.00 0.00 C +ATOM 1982 OD1 ASP 212 11.118 -16.045 5.473 1.00 0.00 O +ATOM 1983 OD2 ASP 212 12.399 -15.929 3.694 1.00 0.00 O +ATOM 1984 C ASP 212 12.905 -12.487 3.860 1.00 0.00 C +ATOM 1985 O ASP 212 14.039 -12.936 4.060 1.00 0.00 O +ATOM 1986 N GLY 213 12.608 -11.633 2.874 1.00 0.00 N +ATOM 1987 H GLY 213 11.694 -11.294 2.752 1.00 0.00 H +ATOM 1988 CA GLY 213 13.612 -11.155 1.930 1.00 0.00 C +ATOM 1989 C GLY 213 13.990 -9.696 2.129 1.00 0.00 C +ATOM 1990 O GLY 213 14.411 -9.312 3.228 1.00 0.00 O +ATOM 1991 N ARG 214 13.837 -8.897 1.066 1.00 0.00 N +ATOM 1992 H ARG 214 13.495 -9.282 0.231 1.00 0.00 H +ATOM 1993 CA ARG 214 14.152 -7.458 1.064 1.00 0.00 C +ATOM 1994 CB ARG 214 15.047 -7.099 -0.136 1.00 0.00 C +ATOM 1995 CG ARG 214 16.463 -7.677 -0.074 1.00 0.00 C +ATOM 1996 CD ARG 214 17.312 -7.261 -1.273 1.00 0.00 C +ATOM 1997 NE ARG 214 17.669 -5.839 -1.250 1.00 0.00 N +ATOM 1998 HE ARG 214 17.323 -5.293 -0.513 1.00 0.00 H +ATOM 1999 CZ ARG 214 18.431 -5.223 -2.155 1.00 0.00 C +ATOM 2000 NH1 ARG 214 18.683 -3.928 -2.023 1.00 0.00 N +ATOM 2001 HH11 ARG 214 18.303 -3.420 -1.250 1.00 0.00 H +ATOM 2002 HH12 ARG 214 19.253 -3.458 -2.698 1.00 0.00 H +ATOM 2003 NH2 ARG 214 18.943 -5.883 -3.189 1.00 0.00 N +ATOM 2004 HH21 ARG 214 18.760 -6.860 -3.298 1.00 0.00 H +ATOM 2005 HH22 ARG 214 19.512 -5.403 -3.857 1.00 0.00 H +ATOM 2006 C ARG 214 12.880 -6.592 1.046 1.00 0.00 C +ATOM 2007 O ARG 214 12.940 -5.394 1.358 1.00 0.00 O +ATOM 2008 N LEU 215 11.737 -7.216 0.724 1.00 0.00 N +ATOM 2009 H LEU 215 11.734 -8.177 0.521 1.00 0.00 H +ATOM 2010 CA LEU 215 10.427 -6.540 0.651 1.00 0.00 C +ATOM 2011 CB LEU 215 9.567 -7.132 -0.501 1.00 0.00 C +ATOM 2012 CG LEU 215 9.896 -7.298 -2.013 1.00 0.00 C +ATOM 2013 CD1 LEU 215 10.200 -5.963 -2.720 1.00 0.00 C +ATOM 2014 CD2 LEU 215 11.017 -8.322 -2.257 1.00 0.00 C +ATOM 2015 C LEU 215 9.638 -6.577 1.972 1.00 0.00 C +ATOM 2016 O LEU 215 9.467 -7.647 2.574 1.00 0.00 O +ATOM 2017 N VAL 216 9.203 -5.390 2.420 1.00 0.00 N +ATOM 2018 H VAL 216 9.397 -4.569 1.916 1.00 0.00 H +ATOM 2019 CA VAL 216 8.424 -5.188 3.657 1.00 0.00 C +ATOM 2020 CB VAL 216 9.202 -4.256 4.699 1.00 0.00 C +ATOM 2021 CG1 VAL 216 9.518 -2.862 4.112 1.00 0.00 C +ATOM 2022 CG2 VAL 216 8.457 -4.149 6.043 1.00 0.00 C +ATOM 2023 C VAL 216 7.028 -4.633 3.295 1.00 0.00 C +ATOM 2024 O VAL 216 6.903 -3.853 2.342 1.00 0.00 O +ATOM 2025 N THR 217 6.001 -5.076 4.033 1.00 0.00 N +ATOM 2026 H THR 217 6.147 -5.726 4.755 1.00 0.00 H +ATOM 2027 CA THR 217 4.610 -4.637 3.829 1.00 0.00 C +ATOM 2028 CB THR 217 3.651 -5.819 3.480 1.00 0.00 C +ATOM 2029 OG1 THR 217 3.828 -6.884 4.422 1.00 0.00 O +ATOM 2030 HG1 THR 217 4.719 -7.240 4.366 1.00 0.00 H +ATOM 2031 CG2 THR 217 3.929 -6.325 2.076 1.00 0.00 C +ATOM 2032 C THR 217 4.044 -3.835 5.008 1.00 0.00 C +ATOM 2033 O THR 217 3.636 -2.685 4.826 1.00 0.00 O +ATOM 2034 N GLY 218 4.007 -4.439 6.203 1.00 0.00 N +ATOM 2035 H GLY 218 4.340 -5.356 6.315 1.00 0.00 H +ATOM 2036 CA GLY 218 3.475 -3.776 7.392 1.00 0.00 C +ATOM 2037 C GLY 218 1.959 -3.812 7.461 1.00 0.00 C +ATOM 2038 O GLY 218 1.397 -4.070 8.527 1.00 0.00 O +ATOM 2039 N VAL 219 1.320 -3.557 6.304 1.00 0.00 N +ATOM 2040 H VAL 219 1.845 -3.324 5.516 1.00 0.00 H +ATOM 2041 CA VAL 219 -0.146 -3.555 6.046 1.00 0.00 C +ATOM 2042 CB VAL 219 -0.623 -5.006 5.491 1.00 0.00 C +ATOM 2043 CG1 VAL 219 -0.155 -6.137 6.383 1.00 0.00 C +ATOM 2044 CG2 VAL 219 -2.113 -5.094 5.202 1.00 0.00 C +ATOM 2045 C VAL 219 -1.090 -2.871 7.092 1.00 0.00 C +ATOM 2046 O VAL 219 -0.695 -2.675 8.241 1.00 0.00 O +ATOM 2047 N ASN 220 -2.304 -2.490 6.646 1.00 0.00 N +ATOM 2048 H ASN 220 -2.550 -2.705 5.735 1.00 0.00 H +ATOM 2049 CA ASN 220 -3.395 -1.801 7.400 1.00 0.00 C +ATOM 2050 CB ASN 220 -3.709 -2.466 8.759 1.00 0.00 C +ATOM 2051 CG ASN 220 -5.202 -2.691 8.983 1.00 0.00 C +ATOM 2052 OD1 ASN 220 -5.750 -3.730 8.609 1.00 0.00 O +ATOM 2053 ND2 ASN 220 -5.862 -1.720 9.608 1.00 0.00 N +ATOM 2054 HD21 ASN 220 -5.376 -0.917 9.893 1.00 0.00 H +ATOM 2055 HD22 ASN 220 -6.821 -1.848 9.760 1.00 0.00 H +ATOM 2056 C ASN 220 -3.178 -0.274 7.579 1.00 0.00 C +ATOM 2057 O ASN 220 -2.051 0.146 7.870 1.00 0.00 O +ATOM 2058 N PRO 221 -4.248 0.572 7.400 1.00 0.00 N +ATOM 2059 CD PRO 221 -5.593 0.234 6.879 1.00 0.00 C +ATOM 2060 CA PRO 221 -4.145 2.042 7.549 1.00 0.00 C +ATOM 2061 CB PRO 221 -5.531 2.530 7.115 1.00 0.00 C +ATOM 2062 CG PRO 221 -5.984 1.492 6.160 1.00 0.00 C +ATOM 2063 C PRO 221 -3.789 2.563 8.958 1.00 0.00 C +ATOM 2064 O PRO 221 -3.338 3.707 9.103 1.00 0.00 O +ATOM 2065 N ALA 222 -3.981 1.707 9.970 1.00 0.00 N +ATOM 2066 H ALA 222 -4.332 0.805 9.798 1.00 0.00 H +ATOM 2067 CA ALA 222 -3.697 2.017 11.382 1.00 0.00 C +ATOM 2068 CB ALA 222 -4.807 1.458 12.271 1.00 0.00 C +ATOM 2069 C ALA 222 -2.332 1.449 11.809 1.00 0.00 C +ATOM 2070 O ALA 222 -1.799 1.826 12.862 1.00 0.00 O +ATOM 2071 N SER 223 -1.774 0.569 10.965 1.00 0.00 N +ATOM 2072 H SER 223 -2.228 0.325 10.128 1.00 0.00 H +ATOM 2073 CA SER 223 -0.479 -0.093 11.195 1.00 0.00 C +ATOM 2074 CB SER 223 -0.643 -1.616 11.067 1.00 0.00 C +ATOM 2075 OG SER 223 -1.676 -2.089 11.914 1.00 0.00 O +ATOM 2076 HG SER 223 -2.525 -1.722 11.652 1.00 0.00 H +ATOM 2077 C SER 223 0.635 0.440 10.260 1.00 0.00 C +ATOM 2078 O SER 223 1.550 -0.300 9.874 1.00 0.00 O +ATOM 2079 N ALA 224 0.544 1.733 9.917 1.00 0.00 N +ATOM 2080 H ALA 224 -0.211 2.271 10.245 1.00 0.00 H +ATOM 2081 CA ALA 224 1.507 2.459 9.060 1.00 0.00 C +ATOM 2082 CB ALA 224 0.947 3.820 8.659 1.00 0.00 C +ATOM 2083 C ALA 224 2.855 2.618 9.784 1.00 0.00 C +ATOM 2084 O ALA 224 3.914 2.650 9.146 1.00 0.00 O +ATOM 2085 N HIS 225 2.780 2.767 11.115 1.00 0.00 N +ATOM 2086 H HIS 225 1.896 2.784 11.547 1.00 0.00 H +ATOM 2087 CA HIS 225 3.940 2.913 12.019 1.00 0.00 C +ATOM 2088 CB HIS 225 3.473 3.133 13.470 1.00 0.00 C +ATOM 2089 CG HIS 225 2.753 4.431 13.698 1.00 0.00 C +ATOM 2090 CD2 HIS 225 1.466 4.690 14.038 1.00 0.00 C +ATOM 2091 ND1 HIS 225 3.376 5.658 13.608 1.00 0.00 N +ATOM 2092 HD1 HIS 225 4.317 5.805 13.377 1.00 0.00 H +ATOM 2093 CE1 HIS 225 2.507 6.615 13.880 1.00 0.00 C +ATOM 2094 NE2 HIS 225 1.341 6.054 14.145 1.00 0.00 N +ATOM 2095 HE2 HIS 225 0.519 6.533 14.379 1.00 0.00 H +ATOM 2096 C HIS 225 4.889 1.702 11.955 1.00 0.00 C +ATOM 2097 O HIS 225 6.110 1.872 12.049 1.00 0.00 O +ATOM 2098 N SER 226 4.316 0.498 11.779 1.00 0.00 N +ATOM 2099 H SER 226 3.339 0.430 11.706 1.00 0.00 H +ATOM 2100 CA SER 226 5.071 -0.770 11.682 1.00 0.00 C +ATOM 2101 CB SER 226 4.134 -1.988 11.795 1.00 0.00 C +ATOM 2102 OG SER 226 3.186 -2.033 10.743 1.00 0.00 O +ATOM 2103 HG SER 226 3.630 -2.127 9.896 1.00 0.00 H +ATOM 2104 C SER 226 5.929 -0.858 10.403 1.00 0.00 C +ATOM 2105 O SER 226 7.109 -1.214 10.482 1.00 0.00 O +ATOM 2106 N THR 227 5.344 -0.491 9.250 1.00 0.00 N +ATOM 2107 H THR 227 4.405 -0.198 9.258 1.00 0.00 H +ATOM 2108 CA THR 227 6.042 -0.497 7.944 1.00 0.00 C +ATOM 2109 CB THR 227 5.048 -0.410 6.713 1.00 0.00 C +ATOM 2110 OG1 THR 227 5.789 -0.357 5.485 1.00 0.00 O +ATOM 2111 HG1 THR 227 6.333 0.434 5.460 1.00 0.00 H +ATOM 2112 CG2 THR 227 4.092 0.787 6.796 1.00 0.00 C +ATOM 2113 C THR 227 7.140 0.589 7.876 1.00 0.00 C +ATOM 2114 O THR 227 8.220 0.354 7.318 1.00 0.00 O +ATOM 2115 N ALA 228 6.848 1.749 8.482 1.00 0.00 N +ATOM 2116 H ALA 228 5.972 1.870 8.918 1.00 0.00 H +ATOM 2117 CA ALA 228 7.755 2.908 8.547 1.00 0.00 C +ATOM 2118 CB ALA 228 7.003 4.132 9.037 1.00 0.00 C +ATOM 2119 C ALA 228 8.990 2.647 9.428 1.00 0.00 C +ATOM 2120 O ALA 228 10.113 2.982 9.030 1.00 0.00 O +ATOM 2121 N VAL 229 8.772 2.014 10.593 1.00 0.00 N +ATOM 2122 H VAL 229 7.853 1.752 10.832 1.00 0.00 H +ATOM 2123 CA VAL 229 9.840 1.672 11.556 1.00 0.00 C +ATOM 2124 CB VAL 229 9.254 1.333 12.998 1.00 0.00 C +ATOM 2125 CG1 VAL 229 8.526 -0.018 13.032 1.00 0.00 C +ATOM 2126 CG2 VAL 229 10.338 1.428 14.084 1.00 0.00 C +ATOM 2127 C VAL 229 10.786 0.580 10.988 1.00 0.00 C +ATOM 2128 O VAL 229 12.009 0.704 11.103 1.00 0.00 O +ATOM 2129 N ARG 230 10.198 -0.436 10.337 1.00 0.00 N +ATOM 2130 H ARG 230 9.215 -0.460 10.259 1.00 0.00 H +ATOM 2131 CA ARG 230 10.928 -1.562 9.715 1.00 0.00 C +ATOM 2132 CB ARG 230 9.968 -2.697 9.332 1.00 0.00 C +ATOM 2133 CG ARG 230 9.352 -3.415 10.534 1.00 0.00 C +ATOM 2134 CD ARG 230 8.313 -4.449 10.128 1.00 0.00 C +ATOM 2135 NE ARG 230 8.912 -5.730 9.750 1.00 0.00 N +ATOM 2136 HE ARG 230 9.810 -5.715 9.357 1.00 0.00 H +ATOM 2137 CZ ARG 230 8.329 -6.920 9.901 1.00 0.00 C +ATOM 2138 NH1 ARG 230 8.971 -8.017 9.524 1.00 0.00 N +ATOM 2139 HH11 ARG 230 9.887 -7.947 9.130 1.00 0.00 H +ATOM 2140 HH12 ARG 230 8.540 -8.912 9.634 1.00 0.00 H +ATOM 2141 NH2 ARG 230 7.112 -7.029 10.425 1.00 0.00 N +ATOM 2142 HH21 ARG 230 6.617 -6.209 10.714 1.00 0.00 H +ATOM 2143 HH22 ARG 230 6.691 -7.930 10.530 1.00 0.00 H +ATOM 2144 C ARG 230 11.759 -1.113 8.500 1.00 0.00 C +ATOM 2145 O ARG 230 12.883 -1.597 8.303 1.00 0.00 O +ATOM 2146 N SER 231 11.210 -0.165 7.724 1.00 0.00 N +ATOM 2147 H SER 231 10.312 0.182 7.935 1.00 0.00 H +ATOM 2148 CA SER 231 11.865 0.411 6.532 1.00 0.00 C +ATOM 2149 CB SER 231 10.867 1.222 5.688 1.00 0.00 C +ATOM 2150 OG SER 231 10.248 2.246 6.448 1.00 0.00 O +ATOM 2151 HG SER 231 10.902 2.882 6.751 1.00 0.00 H +ATOM 2152 C SER 231 13.090 1.270 6.899 1.00 0.00 C +ATOM 2153 O SER 231 14.143 1.135 6.267 1.00 0.00 O +ATOM 2154 N ILE 232 12.957 2.110 7.940 1.00 0.00 N +ATOM 2155 H ILE 232 12.098 2.171 8.421 1.00 0.00 H +ATOM 2156 CA ILE 232 14.055 2.983 8.413 1.00 0.00 C +ATOM 2157 CB ILE 232 13.571 4.199 9.322 1.00 0.00 C +ATOM 2158 CG2 ILE 232 12.749 5.173 8.489 1.00 0.00 C +ATOM 2159 CG1 ILE 232 12.779 3.759 10.569 1.00 0.00 C +ATOM 2160 CD1 ILE 232 13.577 3.721 11.888 1.00 0.00 C +ATOM 2161 C ILE 232 15.232 2.218 9.056 1.00 0.00 C +ATOM 2162 O ILE 232 16.392 2.550 8.787 1.00 0.00 O +ATOM 2163 N ASP 233 14.930 1.197 9.879 1.00 0.00 N +ATOM 2164 H ASP 233 13.991 0.977 10.081 1.00 0.00 H +ATOM 2165 CA ASP 233 15.967 0.367 10.528 1.00 0.00 C +ATOM 2166 CB ASP 233 15.430 -0.464 11.724 1.00 0.00 C +ATOM 2167 CG ASP 233 14.267 -1.403 11.366 1.00 0.00 C +ATOM 2168 OD1 ASP 233 14.395 -2.243 10.445 1.00 0.00 O +ATOM 2169 OD2 ASP 233 13.233 -1.331 12.061 1.00 0.00 O +ATOM 2170 C ASP 233 16.734 -0.505 9.513 1.00 0.00 C +ATOM 2171 O ASP 233 17.940 -0.719 9.666 1.00 0.00 O +ATOM 2172 N ALA 234 16.011 -0.997 8.493 1.00 0.00 N +ATOM 2173 H ALA 234 15.040 -0.827 8.445 1.00 0.00 H +ATOM 2174 CA ALA 234 16.562 -1.824 7.399 1.00 0.00 C +ATOM 2175 CB ALA 234 15.431 -2.428 6.568 1.00 0.00 C +ATOM 2176 C ALA 234 17.499 -0.990 6.504 1.00 0.00 C +ATOM 2177 O ALA 234 18.544 -1.485 6.065 1.00 0.00 O +ATOM 2178 N LEU 235 17.100 0.267 6.246 1.00 0.00 N +ATOM 2179 H LEU 235 16.240 0.584 6.607 1.00 0.00 H +ATOM 2180 CA LEU 235 17.856 1.247 5.435 1.00 0.00 C +ATOM 2181 CB LEU 235 16.954 2.454 5.057 1.00 0.00 C +ATOM 2182 CG LEU 235 16.129 2.693 3.758 1.00 0.00 C +ATOM 2183 CD1 LEU 235 17.021 3.114 2.579 1.00 0.00 C +ATOM 2184 CD2 LEU 235 15.210 1.521 3.367 1.00 0.00 C +ATOM 2185 C LEU 235 19.151 1.746 6.102 1.00 0.00 C +ATOM 2186 O LEU 235 20.196 1.817 5.446 1.00 0.00 O +ATOM 2187 N LYS 236 19.061 2.084 7.398 1.00 0.00 N +ATOM 2188 H LYS 236 18.195 2.001 7.857 1.00 0.00 H +ATOM 2189 CA LYS 236 20.185 2.582 8.221 1.00 0.00 C +ATOM 2190 CB LYS 236 19.671 3.175 9.541 1.00 0.00 C +ATOM 2191 CG LYS 236 18.919 4.493 9.396 1.00 0.00 C +ATOM 2192 CD LYS 236 18.445 5.010 10.745 1.00 0.00 C +ATOM 2193 CE LYS 236 17.696 6.324 10.601 1.00 0.00 C +ATOM 2194 NZ LYS 236 17.226 6.842 11.916 1.00 0.00 N +ATOM 2195 HZ1 LYS 236 16.586 6.149 12.353 1.00 0.00 H +ATOM 2196 HZ2 LYS 236 16.719 7.739 11.774 1.00 0.00 H +ATOM 2197 HZ3 LYS 236 18.043 7.000 12.538 1.00 0.00 H +ATOM 2198 C LYS 236 21.269 1.528 8.515 1.00 0.00 C +ATOM 2199 O LYS 236 22.461 1.854 8.521 1.00 0.00 O +ATOM 2200 N ASN 237 20.836 0.273 8.736 1.00 0.00 N +ATOM 2201 H ASN 237 19.872 0.084 8.702 1.00 0.00 H +ATOM 2202 CA ASN 237 21.678 -0.918 9.042 1.00 0.00 C +ATOM 2203 CB ASN 237 22.489 -1.385 7.810 1.00 0.00 C +ATOM 2204 CG ASN 237 21.604 -1.867 6.667 1.00 0.00 C +ATOM 2205 OD1 ASN 237 21.219 -1.088 5.792 1.00 0.00 O +ATOM 2206 ND2 ASN 237 21.294 -3.160 6.660 1.00 0.00 N +ATOM 2207 HD21 ASN 237 20.726 -3.487 5.931 1.00 0.00 H +ATOM 2208 HD22 ASN 237 21.637 -3.740 7.373 1.00 0.00 H +ATOM 2209 C ASN 237 22.602 -0.821 10.272 1.00 0.00 C +ATOM 2210 O ASN 237 23.223 0.224 10.507 1.00 0.00 O +ATOM 2211 N HIS 238 22.686 -1.925 11.036 1.00 0.00 N +ATOM 2212 H HIS 238 22.172 -2.724 10.786 1.00 0.00 H +ATOM 2213 CA HIS 238 23.502 -2.093 12.273 1.00 0.00 C +ATOM 2214 CB HIS 238 25.017 -2.159 11.962 1.00 0.00 C +ATOM 2215 CG HIS 238 25.425 -3.340 11.127 1.00 0.00 C +ATOM 2216 CD2 HIS 238 26.186 -4.421 11.422 1.00 0.00 C +ATOM 2217 ND1 HIS 238 25.056 -3.484 9.805 1.00 0.00 N +ATOM 2218 HD1 HIS 238 24.500 -2.859 9.296 1.00 0.00 H +ATOM 2219 CE1 HIS 238 25.571 -4.601 9.323 1.00 0.00 C +ATOM 2220 NE2 HIS 238 26.261 -5.188 10.284 1.00 0.00 N +ATOM 2221 HE2 HIS 238 26.748 -6.035 10.200 1.00 0.00 H +ATOM 2222 C HIS 238 23.244 -1.095 13.421 1.00 0.00 C +ATOM 2223 O HIS 238 23.030 0.098 13.175 1.00 0.00 O +ATOM 2224 N HIS 239 23.273 -1.605 14.661 1.00 0.00 N +ATOM 2225 H HIS 239 23.453 -2.561 14.800 1.00 0.00 H +ATOM 2226 CA HIS 239 23.049 -0.818 15.888 1.00 0.00 C +ATOM 2227 CB HIS 239 21.977 -1.508 16.767 1.00 0.00 C +ATOM 2228 CG HIS 239 21.217 -0.575 17.670 1.00 0.00 C +ATOM 2229 CD2 HIS 239 21.191 -0.465 19.021 1.00 0.00 C +ATOM 2230 ND1 HIS 239 20.340 0.377 17.194 1.00 0.00 N +ATOM 2231 HD1 HIS 239 20.138 0.546 16.250 1.00 0.00 H +ATOM 2232 CE1 HIS 239 19.808 1.033 18.210 1.00 0.00 C +ATOM 2233 NE2 HIS 239 20.308 0.541 19.329 1.00 0.00 N +ATOM 2234 HE2 HIS 239 20.085 0.845 20.234 1.00 0.00 H +ATOM 2235 C HIS 239 24.370 -0.659 16.670 1.00 0.00 C +ATOM 2236 O HIS 239 24.509 0.275 17.470 1.00 0.00 O +ATOM 2237 N HIS 240 25.333 -1.560 16.397 1.00 0.00 N +ATOM 2238 H HIS 240 25.159 -2.257 15.727 1.00 0.00 H +ATOM 2239 CA HIS 240 26.690 -1.637 17.010 1.00 0.00 C +ATOM 2240 CB HIS 240 27.549 -0.381 16.709 1.00 0.00 C +ATOM 2241 CG HIS 240 27.855 -0.176 15.253 1.00 0.00 C +ATOM 2242 CD2 HIS 240 29.020 -0.263 14.565 1.00 0.00 C +ATOM 2243 ND1 HIS 240 26.896 0.190 14.332 1.00 0.00 N +ATOM 2244 HD1 HIS 240 25.946 0.334 14.523 1.00 0.00 H +ATOM 2245 CE1 HIS 240 27.455 0.321 13.142 1.00 0.00 C +ATOM 2246 NE2 HIS 240 28.743 0.051 13.256 1.00 0.00 N +ATOM 2247 HE2 HIS 240 29.395 0.072 12.526 1.00 0.00 H +ATOM 2248 C HIS 240 26.746 -1.966 18.514 1.00 0.00 C +ATOM 2249 O HIS 240 27.520 -2.840 18.920 1.00 0.00 O +ATOM 2250 N HIS 241 25.904 -1.281 19.311 1.00 0.00 N +ATOM 2251 H HIS 241 25.304 -0.615 18.925 1.00 0.00 H +ATOM 2252 CA HIS 241 25.758 -1.400 20.791 1.00 0.00 C +ATOM 2253 CB HIS 241 24.595 -2.361 21.186 1.00 0.00 C +ATOM 2254 CG HIS 241 24.693 -3.745 20.603 1.00 0.00 C +ATOM 2255 CD2 HIS 241 23.921 -4.386 19.691 1.00 0.00 C +ATOM 2256 ND1 HIS 241 25.671 -4.645 20.971 1.00 0.00 N +ATOM 2257 HD1 HIS 241 26.386 -4.477 21.620 1.00 0.00 H +ATOM 2258 CE1 HIS 241 25.500 -5.777 20.313 1.00 0.00 C +ATOM 2259 NE2 HIS 241 24.445 -5.646 19.529 1.00 0.00 N +ATOM 2260 HE2 HIS 241 24.092 -6.336 18.929 1.00 0.00 H +ATOM 2261 C HIS 241 27.003 -1.627 21.684 1.00 0.00 C +ATOM 2262 O HIS 241 27.333 -0.763 22.505 1.00 0.00 O +ATOM 2263 N HIS 242 27.680 -2.777 21.500 1.00 0.00 N +ATOM 2264 H HIS 242 27.361 -3.415 20.826 1.00 0.00 H +ATOM 2265 CA HIS 242 28.898 -3.227 22.232 1.00 0.00 C +ATOM 2266 CB HIS 242 30.113 -2.295 21.987 1.00 0.00 C +ATOM 2267 CG HIS 242 30.581 -2.251 20.560 1.00 0.00 C +ATOM 2268 CD2 HIS 242 31.712 -2.717 19.977 1.00 0.00 C +ATOM 2269 ND1 HIS 242 29.855 -1.649 19.554 1.00 0.00 N +ATOM 2270 HD1 HIS 242 28.983 -1.214 19.661 1.00 0.00 H +ATOM 2271 CE1 HIS 242 30.516 -1.745 18.415 1.00 0.00 C +ATOM 2272 NE2 HIS 242 31.646 -2.389 18.644 1.00 0.00 N +ATOM 2273 HE2 HIS 242 32.328 -2.599 17.972 1.00 0.00 H +ATOM 2274 C HIS 242 28.737 -3.497 23.741 1.00 0.00 C +ATOM 2275 O HIS 242 29.214 -4.526 24.235 1.00 0.00 O +ATOM 2276 N HIS 243 28.070 -2.575 24.451 1.00 0.00 N +ATOM 2277 H HIS 243 27.713 -1.772 24.026 1.00 0.00 H +ATOM 2278 CA HIS 243 27.819 -2.668 25.902 1.00 0.00 C +ATOM 2279 CB HIS 243 28.241 -1.364 26.611 1.00 0.00 C +ATOM 2280 CG HIS 243 29.714 -1.076 26.551 1.00 0.00 C +ATOM 2281 CD2 HIS 243 30.657 -1.041 27.524 1.00 0.00 C +ATOM 2282 ND1 HIS 243 30.366 -0.755 25.378 1.00 0.00 N +ATOM 2283 HD1 HIS 243 29.952 -0.696 24.492 1.00 0.00 H +ATOM 2284 CE1 HIS 243 31.645 -0.536 25.630 1.00 0.00 C +ATOM 2285 NE2 HIS 243 31.847 -0.704 26.925 1.00 0.00 N +ATOM 2286 HE2 HIS 243 32.707 -0.603 27.384 1.00 0.00 H +ATOM 2287 C HIS 243 26.351 -2.972 26.203 1.00 0.00 C +ATOM 2288 O HIS 243 25.483 -2.514 25.429 1.00 0.00 O +ATOM 2289 OXT HIS 243 26.087 -3.674 27.204 1.00 0.00 O +END diff --git a/src/jalview/api/AlignViewportI.java b/src/jalview/api/AlignViewportI.java index d15c5fb..b09538e 100644 --- a/src/jalview/api/AlignViewportI.java +++ b/src/jalview/api/AlignViewportI.java @@ -27,6 +27,7 @@ import jalview.datamodel.AlignmentExportData; import jalview.datamodel.AlignmentI; import jalview.datamodel.AlignmentView; import jalview.datamodel.ColumnSelection; +import jalview.datamodel.ContactListI; import jalview.datamodel.ProfilesI; import jalview.datamodel.SearchResultsI; import jalview.datamodel.SequenceCollectionI; @@ -475,6 +476,8 @@ public interface AlignViewportI extends ViewStyleI */ SearchResultsI getSearchResults(); + ContactListI getContactList(AlignmentAnnotation _aa, int column); + /** * Updates view settings with the given font. You may need to call * AlignmentPanel.fontChanged to update the layout geometry. diff --git a/src/jalview/appletgui/#OverviewPanel.java# b/src/jalview/appletgui/#OverviewPanel.java# new file mode 100755 index 0000000..14c3158 --- /dev/null +++ b/src/jalview/appletgui/#OverviewPanel.java# @@ -0,0 +1,453 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.appletgui; + +import jalview.datamodel.SequenceI; +import jalview.viewmodel.OverviewDimensions; +import jalview.datamodel.AlignmentI; +import jalview.renderer.seqfeatures.FeatureColourFinder; + +import java.awt.Color; +import java.awt.Dimension; +import java.awt.Frame; +import java.awt.Graphics; +import java.awt.Image; +import java.awt.Panel; +import java.awt.event.ComponentAdapter; +import java.awt.event.ComponentEvent; +import java.awt.event.MouseEvent; +import java.awt.event.MouseListener; +import java.awt.event.MouseMotionListener; + +public class OverviewPanel extends Panel implements Runnable, + MouseMotionListener, MouseListener +{ + private OverviewDimensions od; + + private Image miniMe; + + private Image offscreen; + + private AlignViewport av; + + private AlignmentPanel ap; + + private boolean resizing = false; + + // This is set true if the user resizes whilst + // the overview is being calculated + private boolean resizeAgain = false; + + // Can set different properties in this seqCanvas than + // main visible SeqCanvas + private SequenceRenderer sr; + + private FeatureRenderer fr; + + private Frame nullFrame; + + public OverviewPanel(AlignmentPanel alPanel) + { + this.av = alPanel.av; + this.ap = alPanel; + setLayout(null); + nullFrame = new Frame(); + nullFrame.addNotify(); + + sr = new SequenceRenderer(av); + sr.graphics = nullFrame.getGraphics(); + sr.renderGaps = false; + sr.forOverview = true; + fr = new FeatureRenderer(av); + + od = new OverviewDimensions(av.getRanges(), av.isShowAnnotation()); + + setSize(new Dimension(od.getWidth(), od.getHeight())); + addComponentListener(new ComponentAdapter() + { + + @Override + public void componentResized(ComponentEvent evt) + { + if ((getWidth() != od.getWidth()) + || (getHeight() != (od.getHeight()))) + { + updateOverviewImage(); + } + } + }); + + addMouseMotionListener(this); + + addMouseListener(this); + + updateOverviewImage(); + + } + + @Override + public void mouseEntered(MouseEvent evt) + { + } + + @Override + public void mouseExited(MouseEvent evt) + { + } + + @Override + public void mouseClicked(MouseEvent evt) + { + } + + @Override + public void mouseMoved(MouseEvent evt) + { + } + + @Override + public void mousePressed(MouseEvent evt) + { + mouseAction(evt); + } + + @Override + public void mouseReleased(MouseEvent evt) + { + mouseAction(evt); + } + + @Override + public void mouseDragged(MouseEvent evt) + { + mouseAction(evt); + } + + private void mouseAction(MouseEvent evt) + { + od.updateViewportFromMouse(evt.getX(), evt.getY(), av.getAlignment() + .getHiddenSequences(), av.getColumnSelection(), av + .getRanges()); + ap.setScrollValues(od.getScrollCol(), od.getScrollRow()); + ap.paintAlignment(false); + } + + /** + * Updates the overview image when the related alignment panel is updated + */ + public void updateOverviewImage() + { + if (resizing) + { + resizeAgain = true; + return; + } + + if (av.isShowSequenceFeatures()) + { + fr.transferSettings(ap.seqPanel.seqCanvas.fr); + } + + resizing = true; + + if ((getSize().width > 0) && (getSize().height > 0)) + { + od.setWidth(getSize().width); + od.setHeight(getSize().height); + } + setSize(new Dimension(od.getWidth(), od.getHeight())); + + Thread thread = new Thread(this); + thread.start(); + repaint(); + } + + @Override + public void run() + { + miniMe = null; + + if (av.isShowSequenceFeatures()) + { + fr.transferSettings(ap.seqPanel.seqCanvas.getFeatureRenderer()); + } + + if (getSize().width > 0 && getSize().height > 0) + { + od.setWidth(getSize().width); + od.setHeight(getSize().height); + } + + setSize(new Dimension(od.getWidth(), od.getHeight())); + + miniMe = nullFrame.createImage(od.getWidth(), od.getHeight()); + offscreen = nullFrame.createImage(od.getWidth(), od.getHeight()); + + Graphics mg = miniMe.getGraphics(); +<<<<<<< HEAD + + int alwidth = av.getAlignment().getWidth(); + int alheight = av.getAlignment().getAbsoluteHeight(); + float sampleCol = alwidth / (float) od.getWidth(); + float sampleRow = alheight / (float) od.getSequencesHeight(); +======= + float sampleCol = (float) alwidth / (float) width; + float sampleRow = (float) alheight / (float) sequencesHeight; + + int lastcol = 0, lastrow = 0; + int xstart = 0, ystart = 0; + Color color = Color.yellow; + int row, col, sameRow = 0, sameCol = 0; + jalview.datamodel.SequenceI seq; + final boolean hasHiddenRows = av.hasHiddenRows(), hasHiddenCols = av + .hasHiddenColumns(); + boolean hiddenRow = false; + AlignmentI alignment = av.getAlignment(); + + FeatureColourFinder finder = new FeatureColourFinder(fr); + for (row = 0; row <= sequencesHeight; row++) + { + if (resizeAgain) + { + break; + } + if ((int) (row * sampleRow) == lastrow) + { + sameRow++; + continue; + } + + hiddenRow = false; + if (hasHiddenRows) + { + seq = alignment.getHiddenSequences().getHiddenSequence(lastrow); + if (seq == null) + { + int index = alignment.getHiddenSequences() + .findIndexWithoutHiddenSeqs(lastrow); + + seq = alignment.getSequenceAt(index); + } + else + { + hiddenRow = true; + } + } + else + { + seq = alignment.getSequenceAt(lastrow); + } + + for (col = 0; col < width; col++) + { + if ((int) (col * sampleCol) == lastcol + && (int) (row * sampleRow) == lastrow) + { + sameCol++; + continue; + } + + lastcol = (int) (col * sampleCol); + + if (seq.getLength() > lastcol) + { + color = sr.getResidueColour(seq, lastcol, finder); + } + else + { + color = Color.white; + } + + if (hiddenRow + || (hasHiddenCols && !av.getColumnSelection().isVisible( + lastcol))) + { + color = color.darker().darker(); + } + + mg.setColor(color); + if (sameCol == 1 && sameRow == 1) + { + mg.drawLine(xstart, ystart, xstart, ystart); + } + else + { + mg.fillRect(xstart, ystart, sameCol, sameRow); + } +>>>>>>> bug/JAL-2436featureRendererThreading + + buildImage(sampleRow, sampleCol, mg); + + if (av.isShowAnnotation()) + { + for (int col = 0; col < od.getWidth() && !resizeAgain; col++) + { + mg.translate(col, od.getSequencesHeight()); + ap.annotationPanel.renderer.drawGraph(mg, + av.getAlignmentConservationAnnotation(), + av.getAlignmentConservationAnnotation().annotations, + (int) (sampleCol) + 1, od.getGraphHeight(), + (int) (col * sampleCol), (int) (col * sampleCol) + 1); + mg.translate(-col, -od.getSequencesHeight()); + } + } + System.gc(); + + resizing = false; + + setBoxPosition(); + + if (resizeAgain) + { + resizeAgain = false; + updateOverviewImage(); + } + } + + /* + * Build the overview panel image + */ + private void buildImage(float sampleRow, float sampleCol, Graphics mg) + { + int lastcol = 0; + int lastrow = 0; + int xstart = 0; + int ystart = 0; + Color color = Color.yellow; + int sameRow = 0; + int sameCol = 0; + + SequenceI seq = null; + + final boolean hasHiddenCols = av.hasHiddenColumns(); + boolean hiddenRow = false; + + for (int row = 0; row <= od.getSequencesHeight() && !resizeAgain; row++) + { + if ((int) (row * sampleRow) == lastrow) + { + sameRow++; + } + else + { + // get the sequence which would be at alignment index 'lastrow' if no + // columns were hidden, and determine whether it is hidden or not + hiddenRow = av.getAlignment().isHidden(lastrow); + seq = av.getAlignment().getSequenceAtAbsoluteIndex(lastrow); + + for (int col = 0; col < od.getWidth(); col++) + { + if ((int) (col * sampleCol) == lastcol + && (int) (row * sampleRow) == lastrow) + { + sameCol++; + } + else + { + lastcol = (int) (col * sampleCol); + + color = getColumnColourFromSequence(seq, hiddenRow, + hasHiddenCols, lastcol); + + mg.setColor(color); + if (sameCol == 1 && sameRow == 1) + { + mg.drawLine(xstart, ystart, xstart, ystart); + } + else + { + mg.fillRect(xstart, ystart, sameCol, sameRow); + } + + xstart = col; + sameCol = 1; + } + } + lastrow = (int) (row * sampleRow); + ystart = row; + sameRow = 1; + } + } + } + + /* + * Find the colour of a sequence at a specified column position + */ + private Color getColumnColourFromSequence( + jalview.datamodel.SequenceI seq, boolean hiddenRow, + boolean hasHiddenCols, int lastcol) + { + Color color; + if (seq.getLength() > lastcol) + { + color = sr.getResidueBoxColour(seq, lastcol); + + if (av.isShowSequenceFeatures()) + { + color = fr.findFeatureColour(color, seq, lastcol); + } + } + else + { + color = Color.white; + } + + if (hiddenRow + || (hasHiddenCols && !av.getColumnSelection() + .isVisible(lastcol))) + { + color = color.darker().darker(); + } + return color; + } + + /** + * Update the overview panel box when the associated alignment panel is + * changed + * + */ + public void setBoxPosition() + { + od.setBoxPosition(av.getAlignment() + .getHiddenSequences(), av.getColumnSelection(), av.getRanges()); + repaint(); + } + + @Override + public void update(Graphics g) + { + paint(g); + } + + @Override + public void paint(Graphics g) + { + Graphics og = offscreen.getGraphics(); + if (miniMe != null) + { + og.drawImage(miniMe, 0, 0, this); + og.setColor(Color.red); + od.drawBox(og); + g.drawImage(offscreen, 0, 0, this); + } + } + +} diff --git a/src/jalview/appletgui/AnnotationPanel.java b/src/jalview/appletgui/AnnotationPanel.java index 34e8b44..aa047d1 100755 --- a/src/jalview/appletgui/AnnotationPanel.java +++ b/src/jalview/appletgui/AnnotationPanel.java @@ -343,7 +343,7 @@ public class AnnotationPanel extends Panel { activeRow = i; } - else if (aa[i].graph > 0) + else if (aa[i].graph != AlignmentAnnotation.NO_GRAPH) { // Stretch Graph graphStretch = i; diff --git a/src/jalview/datamodel/Alignment.java b/src/jalview/datamodel/Alignment.java index a2a152a..9825bff 100755 --- a/src/jalview/datamodel/Alignment.java +++ b/src/jalview/datamodel/Alignment.java @@ -32,6 +32,7 @@ import java.util.Arrays; import java.util.BitSet; import java.util.Collections; import java.util.Enumeration; +import java.util.HashMap; import java.util.HashSet; import java.util.Hashtable; import java.util.Iterator; @@ -1914,12 +1915,11 @@ public class Alignment implements AlignmentI, AutoCloseable @Override public boolean setHiddenColumns(HiddenColumns cols) { - boolean changed = cols == null ? hiddenCols != null - : !cols.equals(hiddenCols); - hiddenCols = cols; - return changed; + boolean changed = cols == null ? hiddenCols != null + : !cols.equals(hiddenCols); + hiddenCols = cols; + return changed; } - @Override public void setupJPredAlignment() { @@ -2032,4 +2032,42 @@ public class Alignment implements AlignmentI, AutoCloseable } } + Map contactmaps = new HashMap<>(); + @Override + public + ContactListI getContactListFor(AlignmentAnnotation _aa, int column) + { + ContactMatrixI cm = contactmaps.get(_aa.annotationId); + if (cm == null) + { + return null; + } + return cm.getContactList(column); + } + + @Override + public AlignmentAnnotation addContactList(ContactMatrixI cm) + { + Annotation _aa[] = new Annotation[getWidth()]; + Annotation dummy = new Annotation(0.0f); + for (int i = 0; i < _aa.length; _aa[i++] = dummy) + { + ; + } + AlignmentAnnotation aa = new AlignmentAnnotation("Contact Matrix", + "Contact Matrix", _aa); + aa.graph = AlignmentAnnotation.CUSTOMRENDERER; + aa.graphMin = cm.getMin(); + aa.graphMax = cm.getMax(); + aa.editable = false; + // aa.autoCalculated = true; + contactmaps.put(aa.annotationId, cm); + // TODO: contact matrices could be intra or inter - more than one refseq possible! + if (cm.hasReferenceSeq()) + { + aa.setSequenceRef(cm.getReferenceSeq()); + } + addAnnotation(aa); + return aa; + } } diff --git a/src/jalview/datamodel/AlignmentAnnotation.java b/src/jalview/datamodel/AlignmentAnnotation.java index 0f41850..2e4a990 100755 --- a/src/jalview/datamodel/AlignmentAnnotation.java +++ b/src/jalview/datamodel/AlignmentAnnotation.java @@ -289,6 +289,8 @@ public class AlignmentAnnotation public static final int LINE_GRAPH = 2; + public static final int CUSTOMRENDERER = 4; + public boolean belowAlignment = true; public SequenceGroup groupRef = null; diff --git a/src/jalview/datamodel/AlignmentI.java b/src/jalview/datamodel/AlignmentI.java index 93a2456..862a2bf 100755 --- a/src/jalview/datamodel/AlignmentI.java +++ b/src/jalview/datamodel/AlignmentI.java @@ -624,4 +624,15 @@ public interface AlignmentI extends AnnotatedCollectionI public HiddenColumns propagateInsertions(SequenceI profileseq, AlignmentView input); + /** + * resolve a contact list instance (if any) associated with the annotation row + * and column position + * + * @param _aa + * @param column + * @return + */ + ContactListI getContactListFor(AlignmentAnnotation _aa, int column); + + AlignmentAnnotation addContactList(ContactMatrixI cm); } diff --git a/src/jalview/datamodel/ContactListI.java b/src/jalview/datamodel/ContactListI.java new file mode 100644 index 0000000..72dbf2e --- /dev/null +++ b/src/jalview/datamodel/ContactListI.java @@ -0,0 +1,16 @@ +package jalview.datamodel; + + +public interface ContactListI extends ContactListProviderI +{ + + /** + * return bounds for range + * + * @param from_column + * @param to_column + * @return double[] { min, max, + */ + ContactRange getRangeFor(int from_column, int to_column); + +} diff --git a/src/jalview/datamodel/ContactListImpl.java b/src/jalview/datamodel/ContactListImpl.java new file mode 100644 index 0000000..6eb4cdb --- /dev/null +++ b/src/jalview/datamodel/ContactListImpl.java @@ -0,0 +1,92 @@ +package jalview.datamodel; + +/** + * helper class to compute min/max/mean for a range on a contact list + * + * @author jprocter + * + */ +public class ContactListImpl implements ContactListI +{ + ContactListProviderI clist; + + + public static ContactListI newContactList(ContactListProviderI list) + { + return new ContactListImpl(list); + } + + public ContactListImpl(ContactListProviderI list) + { + clist = list; + } + + @Override + public double getContactAt(int column) + { + return clist.getContactAt(column); + } + + @Override + public int getContactHeight() + { + return clist.getContactHeight(); + } + + @Override + public ContactRange getRangeFor(int from_column, int to_column) + { + if (clist instanceof ContactListI) + { + // clist may implement getRangeFor in a more efficient way, so use theirs + return ((ContactListI) clist).getRangeFor(from_column, to_column); + } + if (from_column < 0) + { + from_column = 0; + } + if (to_column > getContactHeight()) + { + to_column = getContactHeight(); + } + ContactRange cr = new ContactRange(); + cr.setFrom_column(from_column); + cr.setTo_column(to_column); + double tot = 0; + for (int i = from_column; i < to_column; i++) + { + double contact = getContactAt(i); + tot += contact; + if (i == from_column) + { + cr.setMin(contact); + cr.setMax(contact); + cr.setMinPos(i); + cr.setMaxPos(i); + } + else + { + if (cr.getMax() < contact) + { + cr.setMax(contact); + cr.setMaxPos(i); + } + if (cr.getMin() < contact) + { + cr.setMin(contact); + cr.setMinPos(i); + } + } + } + if (tot > 0) + { + cr.setMean(tot / (to_column - from_column)); + } + else + { + cr.setMean(tot); + } + return cr; + } + +} diff --git a/src/jalview/datamodel/ContactListProviderI.java b/src/jalview/datamodel/ContactListProviderI.java new file mode 100644 index 0000000..37c4e07 --- /dev/null +++ b/src/jalview/datamodel/ContactListProviderI.java @@ -0,0 +1,22 @@ +package jalview.datamodel; + +public interface ContactListProviderI +{ + + /** + * dimension of list where getContactAt(column> contacts = null; + + int width = 0, numcontacts = 0; + + float min = 0f, max = 0f; + + public void addContact(int left, int right, float strength) + { + if (left < 0 || right < 0) + { + throw new Error(new InvalidArgumentException( + "Cannot have negative indices for contact left=" + left + + " right=" + right + " strength=" + strength)); + } + if (symmetric) + { + if (left > right) + { + // swap + int r = right; + right = left; + left = r; + } + } + if (contacts == null) + { + // TODO: use sparse list for efficiency ? + contacts = new ArrayList>(); + } + List clist = contacts.get(left); + if (clist == null) + { + clist = new ArrayList(); + contacts.set(left, clist); + } + Float last = clist.set(right, strength); + // TODO: if last is non null, may need to recompute range + checkBounds(strength); + if (last == null) + { + numcontacts++; + } + } + + private void checkBounds(float strength) + { + if (min > strength) + { + min = strength; + } + if (max < strength) + { + max = strength; + } + } + + + @Override + public ContactListI getContactList(final int column) + { + if (column < 0 || column >= width) + { + return null; + } + + return new ContactListImpl(new ContactListProviderI() + { + int p = column; + + @Override + public int getContactHeight() + { + return width; + + } + + @Override + public double getContactAt(int column) + { + List clist; + Float cl = null; + if (symmetric) + { + if (p < column) + { + clist = contacts.get(p); + cl = clist.get(column); + } + else + { + clist = contacts.get(column); + cl = clist.get(p); + } + } + else + { + clist = contacts.get(p); + cl = clist.get(column); + } + if (cl == null) + { + // return 0 not NaN ? + return Double.NaN; + } + return cl.doubleValue(); + } + }); + } + + @Override + public float getMin() + { + return min; + } + + @Override + public float getMax() + { + return max; + } + + @Override + public boolean hasReferenceSeq() + { + // TODO Auto-generated method stub + return false; + } + + @Override + public SequenceI getReferenceSeq() + { + // TODO Auto-generated method stub + return null; + } +} diff --git a/src/jalview/datamodel/ContactMatrixI.java b/src/jalview/datamodel/ContactMatrixI.java new file mode 100644 index 0000000..c16b457 --- /dev/null +++ b/src/jalview/datamodel/ContactMatrixI.java @@ -0,0 +1,16 @@ +package jalview.datamodel; + +public interface ContactMatrixI +{ + + ContactListI getContactList(int column); + + float getMin(); + + float getMax(); + + boolean hasReferenceSeq(); + + SequenceI getReferenceSeq(); + +} diff --git a/src/jalview/datamodel/ContactRange.java b/src/jalview/datamodel/ContactRange.java new file mode 100644 index 0000000..5de8b04 --- /dev/null +++ b/src/jalview/datamodel/ContactRange.java @@ -0,0 +1,164 @@ +package jalview.datamodel; + + +/** + * bean for max/min positions for a given range + * + * @author jprocter + * + */ +public class ContactRange +{ + int minPos; + + double min; + + int maxPos; + + double max; + + int from_column, to_column; + + private double mean; + + /** + * update the bean with given values + * + * @param from_column + * @param to_column + * @param minPos + * @param min + * @param maxPos + * @param max + */ + public void update(int from_column, int to_column, int minPos, + double min, int maxPos, double max, double mean) + { + this.from_column = from_column; + this.to_column = to_column; + this.minPos = minPos; + this.min = min; + this.maxPos = maxPos; + this.max = max; + this.mean = mean; + } + + /** + * @return the minPos + */ + public int getMinPos() + { + return minPos; + } + + /** + * @param minPos + * the minPos to set + */ + public void setMinPos(int minPos) + { + this.minPos = minPos; + } + + /** + * @return the min + */ + public double getMin() + { + return min; + } + + /** + * @param min + * the min to set + */ + public void setMin(double min) + { + this.min = min; + } + + /** + * @return the maxPos + */ + public int getMaxPos() + { + return maxPos; + } + + /** + * @param maxPos + * the maxPos to set + */ + public void setMaxPos(int maxPos) + { + this.maxPos = maxPos; + } + + /** + * @return the max + */ + public double getMax() + { + return max; + } + + /** + * @param max + * the max to set + */ + public void setMax(double max) + { + this.max = max; + } + + /** + * @return the mean + */ + public double getMean() + { + return mean; + } + + /** + * @param mean + * the mean to set + */ + public void setMean(double mean) + { + this.mean = mean; + } + + /** + * @return the from_column + */ + public int getFrom_column() + { + return from_column; + } + + /** + * @param from_column + * the from_column to set + */ + public void setFrom_column(int from_column) + { + this.from_column = from_column; + } + + /** + * @return the to_column + */ + public int getTo_column() + { + return to_column; + } + + /** + * @param to_column + * the to_column to set + */ + public void setTo_column(int to_column) + { + this.to_column = to_column; + } +} diff --git a/src/jalview/datamodel/Profile.java~ b/src/jalview/datamodel/Profile.java~ new file mode 100644 index 0000000..5464596 --- /dev/null +++ b/src/jalview/datamodel/Profile.java~ @@ -0,0 +1,143 @@ +package jalview.datamodel; + + +/** + * A profile for one column of an alignment + * + * @author gmcarstairs + * + */ +public class Profile implements ProfileI +{ + /* + * an object holding counts of symbols in the profile + */ + private ResidueCount counts; + + /* + * the number of sequences (gapped or not) in the profile + */ + private int height; + + /* + * the number of non-gapped sequences in the profile + */ + private int gapped; + + /* + * the highest count for any residue in the profile + */ + private int maxCount; + + /* + * the residue (e.g. K) or residues (e.g. KQW) with the + * highest count in the profile + */ + private String modalResidue; + + /** + * Constructor which allows derived data to be stored without having to store + * the full profile + * + * @param seqCount + * the number of sequences in the profile + * @param gaps + * the number of gapped sequences + * @param max + * the highest count for any residue + * @param modalres + * the residue (or concatenated residues) with the highest count + */ + public Profile(int seqCount, int gaps, int max, String modalRes) + { + this.height = seqCount; + this.gapped = gaps; + this.maxCount = max; + this.modalResidue = modalRes; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#setCounts(jalview.datamodel.ResidueCount) + */ + @Override + public void setCounts(ResidueCount residueCounts) + { + this.counts = residueCounts; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getPercentageIdentity(boolean) + */ + @Override + public float getPercentageIdentity(boolean ignoreGaps) + { + if (height == 0) + { + return 0f; + } + float pid = 0f; + if (ignoreGaps && gapped < height) + { + pid = (maxCount * 100f) / (height - gapped); + } + else + { + pid = (maxCount * 100f) / height; + } + return pid; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getCounts() + */ + @Override + public ResidueCount getCounts() + { + return counts; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getHeight() + */ + @Override + public int getHeight() + { + return height; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getGapped() + */ + @Override + public int getGapped() + { + return gapped; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getMaxCount() + */ + @Override + public int getMaxCount() + { + return maxCount; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getModalResidue() + */ + @Override + public String getModalResidue() + { + return modalResidue; + } + + /* (non-Javadoc) + * @see jalview.datamodel.ProfileI#getNonGapped() + */ + @Override + public int getNonGapped() + { + return height - gapped; + } +} diff --git a/src/jalview/datamodel/ProfileI.java~ b/src/jalview/datamodel/ProfileI.java~ new file mode 100644 index 0000000..cf2b394 --- /dev/null +++ b/src/jalview/datamodel/ProfileI.java~ @@ -0,0 +1,67 @@ +package jalview.datamodel; + +public interface ProfileI +{ + + /** + * Set the full profile of counts + * + * @param residueCounts + */ + public abstract void setCounts(ResidueCount residueCounts); + + /** + * Returns the percentage identity of the profile, i.e. the highest proportion + * of conserved (equal) symbols. The percentage is as a fraction of all + * sequences, or only ungapped sequences if flag ignoreGaps is set true. + * + * @param ignoreGaps + * @return + */ + public abstract float getPercentageIdentity(boolean ignoreGaps); + + /** + * Returns the full symbol counts for this profile + * + * @return + */ + public abstract ResidueCount getCounts(); + + /** + * Returns the number of sequences in the profile + * + * @return + */ + public abstract int getHeight(); + + /** + * Returns the number of sequences in the profile which had a gap character + * (or were too short to be included in this column's profile) + * + * @return + */ + public abstract int getGapped(); + + /** + * Returns the highest count for any symbol(s) in the profile + * + * @return + */ + public abstract int getMaxCount(); + + /** + * Returns the symbol (or concatenated symbols) which have the highest count + * in the profile, or an empty string if there were no symbols counted + * + * @return + */ + public abstract String getModalResidue(); + + /** + * Answers the number of non-gapped sequences in the profile + * + * @return + */ + public abstract int getNonGapped(); + +} \ No newline at end of file diff --git a/src/jalview/datamodel/Profiles.java~ b/src/jalview/datamodel/Profiles.java~ new file mode 100644 index 0000000..98a8c6d --- /dev/null +++ b/src/jalview/datamodel/Profiles.java~ @@ -0,0 +1,43 @@ +package jalview.datamodel; + +public class Profiles implements ProfilesI +{ + + private ProfileI[] profiles; + + public Profiles(ProfileI[] p) + { + profiles = p; + } + + /** + * Returns the profile for the given column, or null if none found + * + * @param col + */ + @Override + public ProfileI get(int col) + { + return profiles != null && col >= 0 && col < profiles.length ? profiles[col] + : null; + } + + /** + * Returns the first column (base 0) covered by the profiles + */ + @Override + public int getStartColumn() + { + return 0; + } + + /** + * Returns the last column (base 0) covered by the profiles + */ + @Override + public int getEndColumn() + { + return profiles == null ? 0 : profiles.length - 1; + } + +} diff --git a/src/jalview/datamodel/ProfilesI.java~ b/src/jalview/datamodel/ProfilesI.java~ new file mode 100644 index 0000000..6719de6 --- /dev/null +++ b/src/jalview/datamodel/ProfilesI.java~ @@ -0,0 +1,12 @@ +package jalview.datamodel; + +public interface ProfilesI +{ + + ProfileI get(int i); + + int getStartColumn(); + + int getEndColumn(); + +} diff --git a/src/jalview/datamodel/ResidueCount.java~ b/src/jalview/datamodel/ResidueCount.java~ new file mode 100644 index 0000000..0d0348c --- /dev/null +++ b/src/jalview/datamodel/ResidueCount.java~ @@ -0,0 +1,621 @@ +package jalview.datamodel; + +import jalview.util.Comparison; +import jalview.util.Format; +import jalview.util.QuickSort; +import jalview.util.SparseCount; + +/** + * A class to count occurrences of residues in a profile, optimised for speed + * and memory footprint. + * @author gmcarstairs + * + */ +public class ResidueCount +{ + /** + * A data bean to hold the results of counting symbols + */ + public class SymbolCounts + { + /** + * the symbols seen (as char values), in no particular order + */ + public final char[] symbols; + + /** + * the counts for each symbol, in the same order as the symbols + */ + public final int[] values; + + SymbolCounts(char[] s, int[] v) + { + symbols = s; + values = v; + } + } + + private static final int TOUPPERCASE = 'A' - 'a'; + + /* + * nucleotide symbols to count (including N unknown) + */ + private static final String NUCS = "ACGNTU"; + + /* + * amino acid symbols to count (including X unknown) + * NB we also include U so as to support counting of RNA bases + * in the "don't know" case of nucleotide / peptide + */ + private static final String AAS = "ACDEFGHIKLMNPQRSTUVWXY"; + + private static final int GAP_COUNT = 0; + + /* + * fast lookup tables holding the index into our count + * arrays of each symbol; index 0 is reserved for gap counting + */ + private static int[] NUC_INDEX = new int[26]; + + private static int[] AA_INDEX = new int[26]; + static + { + for (int i = 0; i < NUCS.length(); i++) + { + NUC_INDEX[NUCS.charAt(i) - 'A'] = i + 1; + } + for (int i = 0; i < AAS.length(); i++) + { + AA_INDEX[AAS.charAt(i) - 'A'] = i + 1; + } + } + + /* + * counts array, just big enough for the nucleotide or peptide + * character set (plus gap counts in position 0) + */ + private short[] counts; + + /* + * alternative array of int counts for use if any count + * exceeds the maximum value of short (32767) + */ + private int[] intCounts; + + /* + * flag set if we switch from short to int counts + */ + private boolean useIntCounts; + + /* + * general-purpose counter, only for use for characters + * that are not in the expected alphabet + */ + private SparseCount otherData; + + /* + * keeps track of the maximum count value recorded + * (if this class ever allows decrements, would need to + * calculate this on request instead) + */ + int maxCount; + + /* + * if we think we are counting nucleotide, can get by with smaller + * array to hold counts + */ + private boolean isNucleotide; + + /** + * Default constructor allocates arrays able to count either nucleotide or + * peptide bases. Use this constructor if not sure which the data is. + */ + public ResidueCount() + { + this(false); + } + + /** + * Constructor that allocates an array just big enough for the anticipated + * characters, plus one position to count gaps + */ + public ResidueCount(boolean nucleotide) + { + isNucleotide = nucleotide; + int charsToCount = nucleotide ? NUCS.length() : AAS.length(); + counts = new short[charsToCount + 1]; + } + + /** + * Increments the count for the given character. The supplied character may be + * upper or lower case but counts are for the upper case only. Gap characters + * (space, ., -) are all counted together. + * + * @param c + * @return the new value of the count for the character + */ + public int add(final char c) + { + char u = toUpperCase(c); + int newValue = 0; + int offset = getOffset(u); + + /* + * offset 0 is reserved for gap counting, so 0 here means either + * an unexpected character, or a gap character passed in error + */ + if (offset == 0) + { + if (Comparison.isGap(u)) + { + newValue = addGap(); + } + else + { + newValue = addOtherCharacter(u); + } + } + else + { + newValue = increment(offset); + } + return newValue; + } + + /** + * Increment the count at the specified offset. If this would result in short + * overflow, promote to counting int values instead. + * + * @param offset + * @return the new value of the count at this offset + */ + int increment(int offset) + { + int newValue = 0; + if (useIntCounts) + { + newValue = intCounts[offset]; + intCounts[offset] = ++newValue; + } + else + { + if (counts[offset] == Short.MAX_VALUE) + { + handleOverflow(); + newValue = intCounts[offset]; + intCounts[offset] = ++newValue; + } + else + { + newValue = counts[offset]; + counts[offset] = (short) ++newValue; + } + } + maxCount = Math.max(maxCount, newValue); + return newValue; + } + + /** + * Switch from counting in short to counting in int + */ + synchronized void handleOverflow() + { + intCounts = new int[counts.length]; + for (int i = 0; i < counts.length; i++) + { + intCounts[i] = counts[i]; + } + counts = null; + useIntCounts = true; + } + + /** + * Returns this character's offset in the count array + * + * @param c + * @return + */ + int getOffset(char c) + { + int offset = 0; + if ('A' <= c && c <= 'Z') + { + offset = isNucleotide ? NUC_INDEX[c - 'A'] : AA_INDEX[c - 'A']; + } + return offset; + } + + /** + * @param c + * @return + */ + protected char toUpperCase(final char c) + { + char u = c; + if ('a' <= c && c <= 'z') + { + u = (char) (c + TOUPPERCASE); + } + return u; + } + + /** + * Increment count for some unanticipated character. The first time this + * called, a SparseCount is instantiated to hold these 'extra' counts. + * + * @param c + * @return the new value of the count for the character + */ + int addOtherCharacter(char c) + { + if (otherData == null) + { + otherData = new SparseCount(); + } + int newValue = otherData.add(c, 1); + maxCount = Math.max(maxCount, newValue); + return newValue; + } + + /** + * Set count for some unanticipated character. The first time this called, a + * SparseCount is instantiated to hold these 'extra' counts. + * + * @param c + * @param value + */ + void setOtherCharacter(char c, int value) + { + if (otherData == null) + { + otherData = new SparseCount(); + } + otherData.put(c, value); + } + + /** + * Increment count of gap characters + * + * @return the new count of gaps + */ + public int addGap() + { + int newValue; + if (useIntCounts) + { + newValue = ++intCounts[GAP_COUNT]; + } + else + { + newValue = ++counts[GAP_COUNT]; + } + return newValue; + } + + /** + * Answers true if we are counting ints (only after overflow of short counts) + * + * @return + */ + boolean isCountingInts() + { + return useIntCounts; + } + + /** + * Sets the count for the given character. The supplied character may be upper + * or lower case but counts are for the upper case only. + * + * @param c + * @param count + */ + public void put(char c, int count) + { + char u = toUpperCase(c); + int offset = getOffset(u); + + /* + * offset 0 is reserved for gap counting, so 0 here means either + * an unexpected character, or a gap character passed in error + */ + if (offset == 0) + { + if (Comparison.isGap(u)) + { + set(0, count); + } + else + { + setOtherCharacter(u, count); + maxCount = Math.max(maxCount, count); + } + } + else + { + set(offset, count); + maxCount = Math.max(maxCount, count); + } + } + + /** + * Sets the count at the specified offset. If this would result in short + * overflow, promote to counting int values instead. + * + * @param offset + * @param value + */ + void set(int offset, int value) + { + if (useIntCounts) + { + intCounts[offset] = value; + } + else + { + if (value > Short.MAX_VALUE || value < Short.MIN_VALUE) + { + handleOverflow(); + intCounts[offset] = value; + } + else + { + counts[offset] = (short) value; + } + } + } + + /** + * Returns the count for the given character, or zero if no count held + * + * @param c + * @return + */ + public int getCount(char c) + { + char u = toUpperCase(c); + int offset = getOffset(u); + if (offset == 0) + { + if (!Comparison.isGap(u)) + { + // should have called getGapCount() + return otherData == null ? 0 : otherData.get(u); + } + } + return useIntCounts ? intCounts[offset] : counts[offset]; + } + + public int getGapCount() + { + return useIntCounts ? intCounts[0] : counts[0]; + } + + /** + * Answers true if this object wraps a counter for unexpected characters + * + * @return + */ + boolean isUsingOtherData() + { + return otherData != null; + } + + /** + * Returns the character (or concatenated characters) for the symbol(s) with + * the given count in the profile. Can be used to get the modal residue by + * supplying the modal count value. Returns an empty string if no symbol has + * the given count. The symbols are in alphabetic order of standard peptide or + * nucleotide characters, followed by 'other' symbols if any. + * + * @return + */ + public String getResiduesForCount(int count) + { + if (count == 0) + { + return ""; + } + + /* + * find counts for the given value and append the + * corresponding symbol + */ + StringBuilder modal = new StringBuilder(); + if (useIntCounts) + { + for (int i = 1; i < intCounts.length; i++) + { + if (intCounts[i] == count) + { + modal.append(isNucleotide ? NUCS.charAt(i - 1) : AAS + .charAt(i - 1)); + } + } + } + else + { + for (int i = 1; i < counts.length; i++) + { + if (counts[i] == count) + { + modal.append(isNucleotide ? NUCS.charAt(i - 1) : AAS + .charAt(i - 1)); + } + } + } + if (otherData != null) + { + for (int i = 0; i < otherData.size(); i++) + { + if (otherData.valueAt(i) == count) + { + modal.append((char) otherData.keyAt(i)); + } + } + } + return modal.toString(); + } + + /** + * Returns the highest count for any symbol(s) in the profile (excluding gap) + * + * @return + */ + public int getModalCount() + { + return maxCount; + } + + /** + * Returns the number of distinct symbols with a non-zero count (excluding the + * gap symbol) + * + * @return + */ + public int size() { + int size = 0; + if (useIntCounts) + { + for (int i = 1; i < intCounts.length; i++) + { + if (intCounts[i] > 0) + { + size++; + } + } + } + else + { + for (int i = 1; i < counts.length; i++) + { + if (counts[i] > 0) + { + size++; + } + } + } + + /* + * include 'other' characters recorded (even if count is zero + * though that would be a strange use case) + */ + if (otherData != null) + { + size += otherData.size(); + } + + return size; + } + + /** + * Returns a data bean holding those symbols that have a non-zero count + * (excluding the gap symbol), with their counts. + * + * @return + */ + public SymbolCounts getSymbolCounts() + { + int size = size(); + char[] symbols = new char[size]; + int[] values = new int[size]; + int j = 0; + + if (useIntCounts) + { + for (int i = 1; i < intCounts.length; i++) + { + if (intCounts[i] > 0) + { + char symbol = isNucleotide ? NUCS.charAt(i - 1) : AAS + .charAt(i - 1); + symbols[j] = symbol; + values[j] = intCounts[i]; + j++; + } + } + } + else + { + for (int i = 1; i < counts.length; i++) + { + if (counts[i] > 0) + { + char symbol = isNucleotide ? NUCS.charAt(i - 1) : AAS + .charAt(i - 1); + symbols[j] = symbol; + values[j] = counts[i]; + j++; + } + } + } + if (otherData != null) + { + for (int i = 0; i < otherData.size(); i++) + { + symbols[j] = (char) otherData.keyAt(i); + values[j] = otherData.valueAt(i); + j++; + } + } + + return new SymbolCounts(symbols, values); + } + + /** + * Returns a tooltip string showing residues in descending order of their + * percentage frequency in the profile + * + * @param normaliseBy + * the divisor for residue counts (may or may not include gapped + * sequence count) + * @param percentageDecPl + * the number of decimal places to show in percentages + * @return + */ + public String getTooltip(int normaliseBy, int percentageDecPl) + { + SymbolCounts symbolCounts = getSymbolCounts(); + char[] ca = symbolCounts.symbols; + int[] vl = symbolCounts.values; + + /* + * sort characters into ascending order of their counts + */ + QuickSort.sort(vl, ca); + + /* + * traverse in reverse order (highest count first) to build tooltip + */ + boolean first = true; + StringBuilder sb = new StringBuilder(64); + for (int c = ca.length - 1; c >= 0; c--) + { + final char residue = ca[c]; + // TODO combine residues which share a percentage + // (see AAFrequency.completeCdnaConsensus) + float tval = (vl[c] * 100f) / normaliseBy; + sb.append(first ? "" : "; ").append(residue).append(" "); + Format.appendPercentage(sb, tval, percentageDecPl); + sb.append("%"); + first = false; + } + return sb.toString(); + } + + /** + * Returns a string representation of the symbol counts, for debug purposes. + */ + @Override + public String toString() + { + StringBuilder sb = new StringBuilder(); + sb.append("[ "); + SymbolCounts sc = getSymbolCounts(); + for (int i = 0; i < sc.symbols.length; i++) + { + sb.append(sc.symbols[i]).append(":").append(sc.values[i]).append(" "); + } + sb.append("]"); + return sb.toString(); + } +} diff --git a/src/jalview/datamodel/SearchResultMatchI.java~ b/src/jalview/datamodel/SearchResultMatchI.java~ new file mode 100644 index 0000000..732f1dc --- /dev/null +++ b/src/jalview/datamodel/SearchResultMatchI.java~ @@ -0,0 +1,30 @@ +package jalview.datamodel; + +/** + * An interface that describes one matched region of an alignment, as one + * contiguous portion of a single dataset sequence + */ +public interface SearchResultMatchI +{ + /** + * Returns the matched sequence + * + * @return + */ + SequenceI getSequence(); + + /** + * Returns the start position of the match in the sequence (base 1) + * + * @return + */ + int getStart(); + + /** + * Returns the end position of the match in the sequence (base 1) + * + * @return + */ + int getEnd(); + +} \ No newline at end of file diff --git a/src/jalview/datamodel/SearchResultsI.java~ b/src/jalview/datamodel/SearchResultsI.java~ new file mode 100644 index 0000000..93183f2 --- /dev/null +++ b/src/jalview/datamodel/SearchResultsI.java~ @@ -0,0 +1,84 @@ +package jalview.datamodel; + +import java.util.BitSet; +import java.util.List; + +/** + * An interface describing the result of a search or other operation which + * highlights matched regions of an alignment + */ +public interface SearchResultsI +{ + + /** + * Adds one region to the results + * + * @param seq + * Sequence + * @param start + * int + * @param end + * int + * @return + */ + SearchResultMatchI addResult(SequenceI seq, int start, int end); + + /** + * Answers true if the search results include the given sequence (or its + * dataset sequence), else false + * + * @param sequence + * @return + */ + boolean involvesSequence(SequenceI sequence); + + /** + * Returns an array of [from, to, from, to..] matched columns (base 0) between + * the given start and end columns of the given sequence. Returns null if no + * matches overlap the specified region. + *

+ * Implementations should provide an optimised method to return locations to + * highlight on a visible portion of an alignment. + * + * @param sequence + * @param start + * first column of range (base 0, inclusive) + * @param end + * last column of range base 0, inclusive) + * @return int[] + */ + int[] getResults(SequenceI sequence, int start, int end); + + /** + * Returns the number of matches found + * + * @return + */ + int getSize(); + + /** + * Returns true if no search result matches are held. + * + * @return + */ + boolean isEmpty(); + + /** + * Returns the list of matches. + * + * @return + */ + List getResults(); + + /** + * Set bits in a bitfield for all columns in the given sequence collection + * that are highlighted + * + * @param sqcol + * the set of sequences to search for highlighted regions + * @param bs + * bitset to set + * @return number of bits set + */ + int markColumns(SequenceCollectionI sqcol, BitSet bs); +} \ No newline at end of file diff --git a/src/jalview/datamodel/SeqDistanceContactMatrix.java b/src/jalview/datamodel/SeqDistanceContactMatrix.java new file mode 100644 index 0000000..bb2299b --- /dev/null +++ b/src/jalview/datamodel/SeqDistanceContactMatrix.java @@ -0,0 +1,84 @@ +package jalview.datamodel; + +/** + * Dummy contact matrix based on sequence distance + * + * @author jprocter + * + */ +public class SeqDistanceContactMatrix implements ContactMatrixI +{ + private int width = 0; + + public SeqDistanceContactMatrix(int width) + { + this.width = width; + } + + @Override + public float getMin() + { + return 0f; + } + + @Override + public float getMax() + { + return width; + } + @Override + public ContactListI getContactList(final int column) + { + if (column < 0 || column >= width) + { + return null; + } + return new ContactListImpl(new ContactListProviderI() + { + + int p = column; + + // @Override + // public Color getColorForScore(int column) + // { + // return jalview.util.ColorUtils.getGraduatedColour(Math.abs(column-p), + // 0, Color.white, width, Color.magenta); + // } + // @Override + // public Color getColorForRange(int from_column, int to_column) + // { + // return jalview.util.ColorUtils.getGraduatedColour( + // Math.abs(to_column + from_column - 2 * p) / 2, 0, Color.white, width, + // Color.magenta); + // } + + @Override + public int getContactHeight() + { + return width; + + } + + @Override + public double getContactAt(int column) + { + return Math.abs(column - p); + } + }); + } + + @Override + public boolean hasReferenceSeq() + { + // TODO Auto-generated method stub + return false; + } + + @Override + public SequenceI getReferenceSeq() + { + // TODO Auto-generated method stub + return null; + } + +} diff --git a/src/jalview/ext/jmol/JmolParser.java~ b/src/jalview/ext/jmol/JmolParser.java~ new file mode 100644 index 0000000..9b32846 --- /dev/null +++ b/src/jalview/ext/jmol/JmolParser.java~ @@ -0,0 +1,670 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.ext.jmol; + +import jalview.datamodel.AlignmentAnnotation; +import jalview.datamodel.Annotation; +import jalview.datamodel.PDBEntry; +import jalview.datamodel.SequenceI; +import jalview.io.FileParse; +import jalview.io.StructureFile; +import jalview.schemes.ResidueProperties; +import jalview.structure.StructureImportSettings; +import jalview.util.Format; +import jalview.util.MessageManager; + +import java.io.IOException; +import java.util.ArrayList; +import java.util.HashMap; +import java.util.List; +import java.util.Map; +import java.util.Vector; + +import javajs.awt.Dimension; + +import org.jmol.api.JmolStatusListener; +import org.jmol.api.JmolViewer; +import org.jmol.c.CBK; +import org.jmol.c.STR; +import org.jmol.modelset.ModelSet; +import org.jmol.viewer.Viewer; + +import MCview.Atom; +import MCview.PDBChain; +import MCview.Residue; + +/** + * Import and process files with Jmol for file like PDB, mmCIF + * + * @author jprocter + * + */ +public class JmolParser extends StructureFile implements JmolStatusListener +{ + Viewer viewer = null; + + public JmolParser(String inFile, String type) throws IOException + { + super(inFile, type); + } + + public JmolParser(FileParse fp) throws IOException + { + super(fp); + } + + public JmolParser() + { + } + + /** + * Calls the Jmol library to parse the PDB/mmCIF file, and then inspects the + * resulting object model to generate Jalview-style sequences, with secondary + * structure annotation added where available (i.e. where it has been computed + * by Jmol using DSSP). + * + * @see jalview.io.AlignFile#parse() + */ + @Override + public void parse() throws IOException + { + setChains(new Vector()); + Viewer jmolModel = getJmolData(); + jmolModel.openReader(getDataName(), getDataName(), getReader()); + waitForScript(jmolModel); + + /* + * Convert one or more Jmol Model objects to Jalview sequences + */ + if (jmolModel.ms.mc > 0) + { + // ideally we do this + // try + // { + // setStructureFileType(jmolModel.evalString("show _fileType")); + // } catch (Exception q) + // { + // } + // ; + // instead, we distinguish .cif from non-.cif by filename + setStructureFileType(getDataName().toLowerCase().endsWith(".cif") ? PDBEntry.Type.MMCIF + .toString() : "PDB"); + + transformJmolModelToJalview(jmolModel.ms); + } + } + + /** + * create a headless jmol instance for dataprocessing + * + * @return + */ + private Viewer getJmolData() + { + if (viewer == null) + { + try + { + /* + * params -o (output to sysout) -n (nodisplay) -x (exit when finished) + * see http://wiki.jmol.org/index.php/Jmol_Application + */ + viewer = (Viewer) JmolViewer.allocateViewer(null, null, null, null, + null, "-x -o -n", this); + // ensure the 'new' (DSSP) not 'old' (Ramachandran) SS method is used + viewer.setBooleanProperty("defaultStructureDSSP", true); + } catch (ClassCastException x) + { + throw new Error(MessageManager.formatMessage( + "error.jmol_version_not_compatible_with_jalview_version", + new String[] { JmolViewer.getJmolVersion() }), x); + } + } + return viewer; + } + + public void transformJmolModelToJalview(ModelSet ms) throws IOException + { + try + { + String lastID = ""; + List rna = new ArrayList(); + List prot = new ArrayList(); + PDBChain tmpchain; + String pdbId = (String) ms.getInfo(0, "title"); + + if (pdbId == null) + { + setId(safeName(getDataName())); + setPDBIdAvailable(false); + } + else + { + setId(pdbId); + setPDBIdAvailable(true); + } + List significantAtoms = convertSignificantAtoms(ms); + for (Atom tmpatom : significantAtoms) + { + try + { + tmpchain = findChain(tmpatom.chain); + if (tmpatom.resNumIns.trim().equals(lastID)) + { + // phosphorylated protein - seen both CA and P.. + continue; + } + tmpchain.atoms.addElement(tmpatom); + } catch (Exception e) + { + tmpchain = new PDBChain(getId(), tmpatom.chain); + getChains().add(tmpchain); + tmpchain.atoms.addElement(tmpatom); + } + lastID = tmpatom.resNumIns.trim(); + } + xferSettings(); + + makeResidueList(); + makeCaBondList(); + +<<<<<<< HEAD +======= + if (getId() == null) + { + // always use resource name, not the hardwired file + // Does the value of ID get used ? Behaviour needs to be + // documented and tested + setId(getDataName()); + } +>>>>>>> spike/JAL-2040_JAL-2137_phyre2 + for (PDBChain chain : getChains()) + { + SequenceI chainseq = postProcessChain(chain); + if (isRNA(chainseq)) + { + rna.add(chainseq); + } + else + { + prot.add(chainseq); + } + + if (StructureImportSettings.isProcessSecondaryStructure()) + { + createAnnotation(chainseq, chain, ms.at); + } + } + } catch (OutOfMemoryError er) + { + System.out + .println("OUT OF MEMORY LOADING TRANSFORMING JMOL MODEL TO JALVIEW MODEL"); + throw new IOException( + MessageManager + .getString("exception.outofmemory_loading_mmcif_file")); + } + } + + private List convertSignificantAtoms(ModelSet ms) + { + List significantAtoms = new ArrayList(); + HashMap chainTerMap = new HashMap(); + org.jmol.modelset.Atom prevAtom = null; + for (org.jmol.modelset.Atom atom : ms.at) + { + if (atom.getAtomName().equalsIgnoreCase("CA") + || atom.getAtomName().equalsIgnoreCase("P")) + { + if (!atomValidated(atom, prevAtom, chainTerMap)) + { + continue; + } + Atom curAtom = new Atom(atom.x, atom.y, atom.z); + curAtom.atomIndex = atom.getIndex(); + curAtom.chain = atom.getChainIDStr(); + curAtom.insCode = atom.group.getInsertionCode() == '\000' ? ' ' + : atom.group.getInsertionCode(); + curAtom.name = atom.getAtomName(); + curAtom.number = atom.getAtomNumber(); + curAtom.resName = atom.getGroup3(true); + curAtom.resNumber = atom.getResno(); + curAtom.occupancy = ms.occupancies != null ? ms.occupancies[atom + .getIndex()] : Float.valueOf(atom.getOccupancy100()); + String fmt = new Format("%4i").form(curAtom.resNumber); + curAtom.resNumIns = (fmt + curAtom.insCode); + curAtom.tfactor = atom.getBfactor100() / 100f; + curAtom.type = 0; + // significantAtoms.add(curAtom); + // ignore atoms from subsequent models + if (!significantAtoms.contains(curAtom)) + { + significantAtoms.add(curAtom); + } + prevAtom = atom; + } + } + return significantAtoms; + } + + private boolean atomValidated(org.jmol.modelset.Atom curAtom, + org.jmol.modelset.Atom prevAtom, + HashMap chainTerMap) + { + // System.out.println("Atom: " + curAtom.getAtomNumber() + // + " Last atom index " + curAtom.group.lastAtomIndex); + if (chainTerMap == null || prevAtom == null) + { + return true; + } + String curAtomChId = curAtom.getChainIDStr(); + String prevAtomChId = prevAtom.getChainIDStr(); + // new chain encoutered + if (!prevAtomChId.equals(curAtomChId)) + { + // On chain switch add previous chain termination to xTerMap if not exists + if (!chainTerMap.containsKey(prevAtomChId)) + { + chainTerMap.put(prevAtomChId, prevAtom); + } + // if current atom belongs to an already terminated chain and the resNum + // diff < 5 then mark as valid and update termination Atom + if (chainTerMap.containsKey(curAtomChId)) + { + if (curAtom.getResno() < chainTerMap.get(curAtomChId).getResno()) + { + return false; + } + if ((curAtom.getResno() - chainTerMap.get(curAtomChId).getResno()) < 5) + { + chainTerMap.put(curAtomChId, curAtom); + return true; + } + return false; + } + } + // atom with previously terminated chain encountered + else if (chainTerMap.containsKey(curAtomChId)) + { + if (curAtom.getResno() < chainTerMap.get(curAtomChId).getResno()) + { + return false; + } + if ((curAtom.getResno() - chainTerMap.get(curAtomChId).getResno()) < 5) + { + chainTerMap.put(curAtomChId, curAtom); + return true; + } + return false; + } + // HETATM with resNum jump > 2 + return !(curAtom.isHetero() && ((curAtom.getResno() - prevAtom + .getResno()) > 2)); + } + + private void createAnnotation(SequenceI sequence, PDBChain chain, + org.jmol.modelset.Atom[] jmolAtoms) + { + char[] secstr = new char[sequence.getLength()]; + char[] secstrcode = new char[sequence.getLength()]; + + // Ensure Residue size equals Seq size + if (chain.residues.size() != sequence.getLength()) + { + return; + } + int annotIndex = 0; + for (Residue residue : chain.residues) + { + Atom repAtom = residue.getAtoms().get(0); + STR proteinStructureSubType = jmolAtoms[repAtom.atomIndex].group + .getProteinStructureSubType(); + setSecondaryStructure(proteinStructureSubType, annotIndex, secstr, + secstrcode); + ++annotIndex; + } + addSecondaryStructureAnnotation(chain.pdbid, sequence, secstr, + secstrcode, chain.id, sequence.getStart()); + } + + /** + * Helper method that adds an AlignmentAnnotation for secondary structure to + * the sequence, provided at least one secondary structure prediction has been + * made + * + * @param modelTitle + * @param seq + * @param secstr + * @param secstrcode + * @param chainId + * @param firstResNum + * @return + */ + protected void addSecondaryStructureAnnotation(String modelTitle, + SequenceI sq, char[] secstr, char[] secstrcode, String chainId, + int firstResNum) + { + char[] seq = sq.getSequence(); + boolean ssFound = false; + Annotation asecstr[] = new Annotation[seq.length + firstResNum - 1]; + for (int p = 0; p < seq.length; p++) + { + if (secstr[p] >= 'A' && secstr[p] <= 'z') + { + try + { + asecstr[p] = new Annotation(String.valueOf(secstr[p]), null, + secstrcode[p], Float.NaN); + ssFound = true; + } catch (Exception e) + { + // e.printStackTrace(); + } + } + } + + if (ssFound) + { + String mt = modelTitle == null ? getDataName() : modelTitle; + mt += chainId; + AlignmentAnnotation ann = new AlignmentAnnotation( + "Secondary Structure", "Secondary Structure for " + mt, + asecstr); + ann.belowAlignment = true; + ann.visible = true; + ann.autoCalculated = false; + ann.setCalcId(getClass().getName()); + ann.adjustForAlignment(); + ann.validateRangeAndDisplay(); + annotations.add(ann); + sq.addAlignmentAnnotation(ann); + } + } + + private void waitForScript(Viewer jmd) + { + while (jmd.isScriptExecuting()) + { + try + { + Thread.sleep(50); + + } catch (InterruptedException x) + { + } + } + } + + /** + * Convert Jmol's secondary structure code to Jalview's, and stored it in the + * secondary structure arrays at the given sequence position + * + * @param proteinStructureSubType + * @param pos + * @param secstr + * @param secstrcode + */ + protected void setSecondaryStructure(STR proteinStructureSubType, + int pos, char[] secstr, char[] secstrcode) + { + switch (proteinStructureSubType) + { + case HELIX310: + secstr[pos] = '3'; + break; + case HELIX: + case HELIXALPHA: + secstr[pos] = 'H'; + break; + case HELIXPI: + secstr[pos] = 'P'; + break; + case SHEET: + secstr[pos] = 'E'; + break; + default: + secstr[pos] = 0; + } + + switch (proteinStructureSubType) + { + case HELIX310: + case HELIXALPHA: + case HELIXPI: + case HELIX: + secstrcode[pos] = 'H'; + break; + case SHEET: + secstrcode[pos] = 'E'; + break; + default: + secstrcode[pos] = 0; + } + } + + /** + * Convert any non-standard peptide codes to their standard code table + * equivalent. (Initial version only does Selenomethionine MSE->MET.) + * + * @param threeLetterCode + * @param seq + * @param pos + */ + protected void replaceNonCanonicalResidue(String threeLetterCode, + char[] seq, int pos) + { + String canonical = ResidueProperties + .getCanonicalAminoAcid(threeLetterCode); + if (canonical != null && !canonical.equalsIgnoreCase(threeLetterCode)) + { + seq[pos] = ResidueProperties.getSingleCharacterCode(canonical); + } + } + + /** + * Not implemented - returns null + */ + @Override + public String print() + { + return null; + } + + /** + * Not implemented + */ + @Override + public void setCallbackFunction(String callbackType, + String callbackFunction) + { + } + + @Override + public void notifyCallback(CBK cbType, Object[] data) + { + String strInfo = (data == null || data[1] == null ? null : data[1] + .toString()); + switch (cbType) + { + case ECHO: + sendConsoleEcho(strInfo); + break; + case SCRIPT: + notifyScriptTermination((String) data[2], + ((Integer) data[3]).intValue()); + break; + case MEASURE: + String mystatus = (String) data[3]; + if (mystatus.indexOf("Picked") >= 0 + || mystatus.indexOf("Sequence") >= 0) + { + // Picking mode + sendConsoleMessage(strInfo); + } + else if (mystatus.indexOf("Completed") >= 0) + { + sendConsoleEcho(strInfo.substring(strInfo.lastIndexOf(",") + 2, + strInfo.length() - 1)); + } + break; + case MESSAGE: + sendConsoleMessage(data == null ? null : strInfo); + break; + case PICK: + sendConsoleMessage(strInfo); + break; + default: + break; + } + } + + String lastConsoleEcho = ""; + + private void sendConsoleEcho(String string) + { + lastConsoleEcho += string; + lastConsoleEcho += "\n"; + } + + String lastConsoleMessage = ""; + + private void sendConsoleMessage(String string) + { + lastConsoleMessage += string; + lastConsoleMessage += "\n"; + } + + int lastScriptTermination = -1; + + String lastScriptMessage = ""; + + private void notifyScriptTermination(String string, int intValue) + { + lastScriptMessage += string; + lastScriptMessage += "\n"; + lastScriptTermination = intValue; + } + + @Override + public boolean notifyEnabled(CBK callbackPick) + { + switch (callbackPick) + { + case MESSAGE: + case SCRIPT: + case ECHO: + case LOADSTRUCT: + case ERROR: + return true; + default: + return false; + } + } + + /** + * Not implemented - returns null + */ + @Override + public String eval(String strEval) + { + return null; + } + + /** + * Not implemented - returns null + */ + @Override + public float[][] functionXY(String functionName, int x, int y) + { + return null; + } + + /** + * Not implemented - returns null + */ + @Override + public float[][][] functionXYZ(String functionName, int nx, int ny, int nz) + { + return null; + } + + /** + * Not implemented - returns null + */ + @Override + public String createImage(String fileName, String imageType, + Object text_or_bytes, int quality) + { + return null; + } + + /** + * Not implemented - returns null + */ + @Override + public Map getRegistryInfo() + { + return null; + } + + /** + * Not implemented + */ + @Override + public void showUrl(String url) + { + } + + /** + * Not implemented - returns null + */ + @Override + public Dimension resizeInnerPanel(String data) + { + return null; + } + + @Override + public Map getJSpecViewProperty(String arg0) + { + return null; + } + + public boolean isPredictSecondaryStructure() + { + return predictSecondaryStructure; + } + + public void setPredictSecondaryStructure(boolean predictSecondaryStructure) + { + this.predictSecondaryStructure = predictSecondaryStructure; + } + + public boolean isVisibleChainAnnotation() + { + return visibleChainAnnotation; + } + + public void setVisibleChainAnnotation(boolean visibleChainAnnotation) + { + this.visibleChainAnnotation = visibleChainAnnotation; + } + +} diff --git a/src/jalview/gui/#OverviewPanel.java# b/src/jalview/gui/#OverviewPanel.java# new file mode 100755 index 0000000..ce3abb5 --- /dev/null +++ b/src/jalview/gui/#OverviewPanel.java# @@ -0,0 +1,468 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.gui; + +import jalview.datamodel.SequenceI; +import jalview.renderer.AnnotationRenderer; +import jalview.viewmodel.OverviewDimensions; +import jalview.renderer.seqfeatures.FeatureColourFinder; + +import java.awt.Color; +import java.awt.Dimension; +import java.awt.Graphics; +import java.awt.event.ComponentAdapter; +import java.awt.event.ComponentEvent; +import java.awt.event.MouseAdapter; +import java.awt.event.MouseEvent; +import java.awt.event.MouseMotionAdapter; +import java.awt.image.BufferedImage; + +import javax.swing.JPanel; + +/** + * Panel displaying an overview of the full alignment, with an interactive box + * representing the viewport onto the alignment. + * + * @author $author$ + * @version $Revision$ + */ +public class OverviewPanel extends JPanel implements Runnable +{ + private static final Color TRANS_GREY = new Color(100, 100, 100, 25); + + private final AnnotationRenderer renderer = new AnnotationRenderer(); + + private OverviewDimensions od; + + private BufferedImage miniMe; + + private BufferedImage lastMiniMe = null; + + private AlignViewport av; + + private AlignmentPanel ap; + + // + private boolean resizing = false; + + // This is set true if the user resizes whilst + // the overview is being calculated + private boolean resizeAgain = false; + + // Can set different properties in this seqCanvas than + // main visible SeqCanvas + private SequenceRenderer sr; + + private jalview.renderer.seqfeatures.FeatureRenderer fr; + + /** + * Creates a new OverviewPanel object. + * + * @param alPanel + * The alignment panel which is shown in the overview panel + */ + public OverviewPanel(AlignmentPanel alPanel) + { + this.av = alPanel.av; + this.ap = alPanel; + setLayout(null); + + sr = new SequenceRenderer(av); + sr.renderGaps = false; + sr.forOverview = true; + fr = new FeatureRenderer(alPanel); + + od = new OverviewDimensions(av.getRanges(), av.isShowAnnotation()); + + addComponentListener(new ComponentAdapter() + { + @Override + public void componentResized(ComponentEvent evt) + { + if ((getWidth() != od.getWidth()) + || (getHeight() != (od.getHeight()))) + { + updateOverviewImage(); + } + } + }); + + addMouseMotionListener(new MouseMotionAdapter() + { + @Override + public void mouseDragged(MouseEvent evt) + { + if (!av.getWrapAlignment()) + { + od.updateViewportFromMouse(evt.getX(), evt.getY(), av + .getAlignment().getHiddenSequences(), av + .getColumnSelection(), av.getRanges()); + ap.setScrollValues(od.getScrollCol(), od.getScrollRow()); + } + } + }); + + addMouseListener(new MouseAdapter() + { + @Override + public void mousePressed(MouseEvent evt) + { + if (!av.getWrapAlignment()) + { + od.updateViewportFromMouse(evt.getX(), evt.getY(), av + .getAlignment().getHiddenSequences(), av + .getColumnSelection(), av.getRanges()); + ap.setScrollValues(od.getScrollCol(), od.getScrollRow()); + } + } + }); + + updateOverviewImage(); + } + + /** + * Updates the overview image when the related alignment panel is updated + */ + public void updateOverviewImage() + { + if (resizing) + { + resizeAgain = true; + return; + } + + resizing = true; + + if ((getWidth() > 0) && (getHeight() > 0)) + { + od.setWidth(getWidth()); + od.setHeight(getHeight()); + } + + setPreferredSize(new Dimension(od.getWidth(), od.getHeight())); + + Thread thread = new Thread(this); + thread.start(); + repaint(); + } + + @Override + public void run() + { + miniMe = null; + + if (av.isShowSequenceFeatures()) + { + fr.transferSettings(ap.getSeqPanel().seqCanvas.getFeatureRenderer()); + } + + // why do we need to set preferred size again? was set in + // updateOverviewImage + setPreferredSize(new Dimension(od.getWidth(), od.getHeight())); + + miniMe = new BufferedImage(od.getWidth(), od.getHeight(), + BufferedImage.TYPE_INT_RGB); + + Graphics mg = miniMe.getGraphics(); + mg.setColor(Color.orange); + mg.fillRect(0, 0, od.getWidth(), miniMe.getHeight()); + +<<<<<<< HEAD + // calculate sampleCol and sampleRow + // alignment width is max number of residues/bases + // alignment height is number of sequences + int alwidth = av.getAlignment().getWidth(); + int alheight = av.getAlignment().getAbsoluteHeight(); + + // sampleCol or sampleRow is the width/height allocated to each residue + // in particular, sometimes we may need more than one row/col of the + // BufferedImage allocated + // sampleCol is how much of a residue to assign to each pixel + // sampleRow is how many sequences to assign to each pixel + float sampleCol = alwidth / (float) od.getWidth(); + float sampleRow = alheight / (float) od.getSequencesHeight(); + + buildImage(sampleRow, sampleCol); +======= + float sampleCol = (float) alwidth / (float) width; + float sampleRow = (float) alheight / (float) sequencesHeight; + + int lastcol = -1, lastrow = -1; + Color color = Color.white; + int row, col; + jalview.datamodel.SequenceI seq; + final boolean hasHiddenRows = av.hasHiddenRows(), hasHiddenCols = av + .hasHiddenColumns(); + boolean hiddenRow = false; + // get hidden row and hidden column map once at beginning. + // clone featureRenderer settings to avoid race conditions... if state is + // updated just need to refresh again + + FeatureColourFinder finder = new FeatureColourFinder(fr); + + for (row = 0; row < sequencesHeight; row++) + { + if (resizeAgain) + { + break; + } + if ((int) (row * sampleRow) == lastrow) + { + // No need to recalculate the colours, + // Just copy from the row above + for (col = 0; col < width; col++) + { + if (resizeAgain) + { + break; + } + miniMe.setRGB(col, row, miniMe.getRGB(col, row - 1)); + } + continue; + } + + lastrow = (int) (row * sampleRow); + + hiddenRow = false; + if (hasHiddenRows) + { + seq = av.getAlignment().getHiddenSequences() + .getHiddenSequence(lastrow); + if (seq == null) + { + int index = av.getAlignment().getHiddenSequences() + .findIndexWithoutHiddenSeqs(lastrow); + + seq = av.getAlignment().getSequenceAt(index); + } + else + { + hiddenRow = true; + } + } + else + { + seq = av.getAlignment().getSequenceAt(lastrow); + } + + if (seq == null) + { + System.out.println(lastrow + " null"); + continue; + } + + for (col = 0; col < width; col++) + { + if (resizeAgain) + { + break; + } + if ((int) (col * sampleCol) == lastcol + && (int) (row * sampleRow) == lastrow) + { + miniMe.setRGB(col, row, color.getRGB()); + continue; + } + + lastcol = (int) (col * sampleCol); + + if (seq.getLength() > lastcol) + { + color = sr.getResidueColour(seq, lastcol, finder); + } + else + { + color = Color.WHITE; + } + + if (hiddenRow + || (hasHiddenCols && !av.getColumnSelection().isVisible( + lastcol))) + { + color = color.darker().darker(); + } + + miniMe.setRGB(col, row, color.getRGB()); +>>>>>>> bug/JAL-2436featureRendererThreading + + if (av.isShowAnnotation()) + { + renderer.updateFromAlignViewport(av); + for (int col = 0; col < od.getWidth() && !resizeAgain; col++) + { + mg.translate(col, od.getSequencesHeight()); + renderer.drawGraph(mg, av.getAlignmentConservationAnnotation(), + av.getAlignmentConservationAnnotation().annotations, + (int) (sampleCol) + 1, od.getGraphHeight(), + (int) (col * sampleCol), (int) (col * sampleCol) + 1); + mg.translate(-col, -od.getSequencesHeight()); + + } + } + System.gc(); + + resizing = false; + + if (resizeAgain) + { + resizeAgain = false; + updateOverviewImage(); + } + else + { + lastMiniMe = miniMe; + } + + setBoxPosition(); + } + + /* + * Build the overview panel image + */ + private void buildImage(float sampleRow, float sampleCol) + { + int lastcol = -1; + int lastrow = -1; + int color = Color.white.getRGB(); + + SequenceI seq = null; + + final boolean hasHiddenCols = av.hasHiddenColumns(); + boolean hiddenRow = false; + // get hidden row and hidden column map once at beginning. + // clone featureRenderer settings to avoid race conditions... if state is + // updated just need to refresh again + for (int row = 0; row < od.getSequencesHeight() && !resizeAgain; row++) + { + boolean doCopy = true; + int currentrow = (int) (row * sampleRow); + if (currentrow != lastrow) + { + doCopy = false; + + lastrow = currentrow; + + // get the sequence which would be at alignment index 'lastrow' if no + // rows were hidden, and determine whether it is hidden or not + hiddenRow = av.getAlignment().isHidden(lastrow); + seq = av.getAlignment().getSequenceAtAbsoluteIndex(lastrow); + } + + for (int col = 0; col < od.getWidth() && !resizeAgain; col++) + { + if (doCopy) + { + color = miniMe.getRGB(col, row - 1); + } + else if ((int) (col * sampleCol) != lastcol + || (int) (row * sampleRow) != lastrow) + { + lastcol = (int) (col * sampleCol); + color = getColumnColourFromSequence(seq, hiddenRow, hasHiddenCols, + lastcol); + } + // else we just use the color we already have , so don't need to set it + + miniMe.setRGB(col, row, color); + } + } + } + + /* + * Find the colour of a sequence at a specified column position + */ + private int getColumnColourFromSequence(jalview.datamodel.SequenceI seq, + boolean hiddenRow, boolean hasHiddenCols, int lastcol) + { + int color; + + if (seq == null) + { + color = Color.white.getRGB(); + } + else if (seq.getLength() > lastcol) + { + color = sr.getResidueBoxColour(seq, lastcol).getRGB(); + + if (av.isShowSequenceFeatures()) + { + color = fr.findFeatureColour(color, seq, lastcol); + } + } + else + { + color = Color.white.getRGB(); + } + + if (hiddenRow + || (hasHiddenCols && !av.getColumnSelection() + .isVisible(lastcol))) + { + color = new Color(color).darker().darker().getRGB(); + } + + return color; + } + + /** + * Update the overview panel box when the associated alignment panel is + * changed + * + */ + public void setBoxPosition() + { + od.setBoxPosition(av.getAlignment() + .getHiddenSequences(), av.getColumnSelection(), av.getRanges()); + repaint(); + } + + + @Override + public void paintComponent(Graphics g) + { + if (resizing || resizeAgain) + { + if (lastMiniMe == null) + { + g.setColor(Color.white); + g.fillRect(0, 0, getWidth(), getHeight()); + } + else + { + g.drawImage(lastMiniMe, 0, 0, getWidth(), getHeight(), this); + } + g.setColor(TRANS_GREY); + g.fillRect(0, 0, getWidth(), getHeight()); + } + else if (lastMiniMe != null) + { + g.drawImage(lastMiniMe, 0, 0, this); + if (lastMiniMe != miniMe) + { + g.setColor(TRANS_GREY); + g.fillRect(0, 0, getWidth(), getHeight()); + } + } + + g.setColor(Color.red); + od.drawBox(g); + } +} diff --git a/src/jalview/gui/AnnotationPanel.java b/src/jalview/gui/AnnotationPanel.java index e9ef19c..7c28bd0 100755 --- a/src/jalview/gui/AnnotationPanel.java +++ b/src/jalview/gui/AnnotationPanel.java @@ -551,7 +551,7 @@ public class AnnotationPanel extends JPanel implements AwtRenderPanelI, { activeRow = i; } - else if (aa[i].graph > 0) + else if (aa[i].graph != 0) { /* * we have clicked on a resizable graph annotation diff --git a/src/jalview/gui/SeqCanvas.java.broken b/src/jalview/gui/SeqCanvas.java.broken new file mode 100755 index 0000000..c0a86df --- /dev/null +++ b/src/jalview/gui/SeqCanvas.java.broken @@ -0,0 +1,980 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.gui; + +import jalview.datamodel.AlignmentI; +import jalview.datamodel.SearchResults; +import jalview.datamodel.SequenceGroup; +import jalview.datamodel.SequenceI; + +import java.awt.BasicStroke; +import java.awt.BorderLayout; +import java.awt.Color; +import java.awt.FontMetrics; +import java.awt.Graphics; +import java.awt.Graphics2D; +import java.awt.RenderingHints; +import java.awt.Shape; +import java.awt.image.BufferedImage; +import java.util.List; + +import javax.swing.JComponent; + +/** + * DOCUMENT ME! + * + * @author $author$ + * @version $Revision$ + */ +public class SeqCanvas extends JComponent +{ + final FeatureRenderer fr; + + final SequenceRenderer sr; + + BufferedImage img; + + Graphics2D gg; + + int imgWidth; + + int imgHeight; + + AlignViewport av; + + SearchResults searchResults = null; + + boolean fastPaint = false; + + int LABEL_WEST; + + int LABEL_EAST; + + int cursorX = 0; + + int cursorY = 0; + + /** + * Creates a new SeqCanvas object. + * + * @param av + * DOCUMENT ME! + */ + public SeqCanvas(AlignmentPanel ap) + { + this.av = ap.av; + updateViewport(); + fr = new FeatureRenderer(ap); + sr = new SequenceRenderer(av); + setLayout(new BorderLayout()); + PaintRefresher.Register(this, av.getSequenceSetId()); + setBackground(Color.white); + } + + public SequenceRenderer getSequenceRenderer() + { + return sr; + } + + public FeatureRenderer getFeatureRenderer() + { + return fr; + } + + int charHeight = 0, charWidth = 0; + + private void updateViewport() + { + charHeight = av.getCharHeight(); + charWidth = av.getCharWidth(); + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + * @param startx + * DOCUMENT ME! + * @param endx + * DOCUMENT ME! + * @param ypos + * DOCUMENT ME! + */ + private void drawNorthScale(Graphics g, int startx, int endx, int ypos) + { + updateViewport(); + int scalestartx = startx - (startx % 10) + 10; + + g.setColor(Color.black); + // NORTH SCALE + for (int i = scalestartx; i < endx; i += 10) + { + int value = i; + if (av.hasHiddenColumns()) + { + value = av.getColumnSelection().adjustForHiddenColumns(value); + } + + g.drawString(String.valueOf(value), (i - startx - 1) * charWidth, + ypos - (charHeight / 2)); + + g.drawLine(((i - startx - 1) * charWidth) + (charWidth / 2), + (ypos + 2) - (charHeight / 2), ((i - startx - 1) * charWidth) + + (charWidth / 2), ypos - 2); + } + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + * @param startx + * DOCUMENT ME! + * @param endx + * DOCUMENT ME! + * @param ypos + * DOCUMENT ME! + */ + void drawWestScale(Graphics g, int startx, int endx, int ypos) + { + FontMetrics fm = getFontMetrics(av.getFont()); + ypos += charHeight; + + if (av.hasHiddenColumns()) + { + startx = av.getColumnSelection().adjustForHiddenColumns(startx); + endx = av.getColumnSelection().adjustForHiddenColumns(endx); + } + + int maxwidth = av.getAlignment().getWidth(); + if (av.hasHiddenColumns()) + { + maxwidth = av.getColumnSelection().findColumnPosition(maxwidth) - 1; + } + + // WEST SCALE + for (int i = 0; i < av.getAlignment().getHeight(); i++) + { + SequenceI seq = av.getAlignment().getSequenceAt(i); + int index = startx; + int value = -1; + + while (index < endx) + { + if (jalview.util.Comparison.isGap(seq.getCharAt(index))) + { + index++; + + continue; + } + + value = av.getAlignment().getSequenceAt(i).findPosition(index); + + break; + } + + if (value != -1) + { + int x = LABEL_WEST - fm.stringWidth(String.valueOf(value)) + - charWidth / 2; + g.drawString(value + "", x, (ypos + (i * charHeight)) + - (charHeight / 5)); + } + } + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + * @param startx + * DOCUMENT ME! + * @param endx + * DOCUMENT ME! + * @param ypos + * DOCUMENT ME! + */ + void drawEastScale(Graphics g, int startx, int endx, int ypos) + { + ypos += charHeight; + + if (av.hasHiddenColumns()) + { + endx = av.getColumnSelection().adjustForHiddenColumns(endx); + } + + SequenceI seq; + // EAST SCALE + for (int i = 0; i < av.getAlignment().getHeight(); i++) + { + seq = av.getAlignment().getSequenceAt(i); + int index = endx; + int value = -1; + + while (index > startx) + { + if (jalview.util.Comparison.isGap(seq.getCharAt(index))) + { + index--; + + continue; + } + + value = seq.findPosition(index); + + break; + } + + if (value != -1) + { + g.drawString(String.valueOf(value), 0, (ypos + (i * charHeight)) + - (charHeight / 5)); + } + } + } + + boolean fastpainting = false; + + /** + * need to make this thread safe move alignment rendering in response to + * slider adjustment + * + * @param horizontal + * shift along + * @param vertical + * shift up or down in repaint + */ + public void fastPaint(int horizontal, int vertical) + { + if (fastpainting || gg == null) + { + return; + } + fastpainting = true; + fastPaint = true; + updateViewport(); + gg.copyArea(horizontal * charWidth, vertical * charHeight, imgWidth, + imgHeight, -horizontal * charWidth, -vertical * charHeight); + + int sr = av.startRes; + int er = av.endRes; + int ss = av.startSeq; + int es = av.endSeq; + int transX = 0; + int transY = 0; + + if (horizontal > 0) // scrollbar pulled right, image to the left + { + er++; + transX = (er - sr - horizontal) * charWidth; + sr = er - horizontal; + } + else if (horizontal < 0) + { + er = sr - horizontal - 1; + } + else if (vertical > 0) // scroll down + { + ss = es - vertical; + + if (ss < av.startSeq) + { // ie scrolling too fast, more than a page at a time + ss = av.startSeq; + } + else + { + transY = imgHeight - (vertical * charHeight); + } + } + else if (vertical < 0) + { + es = ss - vertical; + + if (es > av.endSeq) + { + es = av.endSeq; + } + } + + gg.translate(transX, transY); + drawPanel(gg, sr, er, ss, es, 0); + gg.translate(-transX, -transY); + + repaint(); + fastpainting = false; + } + + /** + * Definitions of startx and endx (hopefully): SMJS This is what I'm working + * towards! startx is the first residue (starting at 0) to display. endx is + * the last residue to display (starting at 0). starty is the first sequence + * to display (starting at 0). endy is the last sequence to display (starting + * at 0). NOTE 1: The av limits are set in setFont in this class and in the + * adjustment listener in SeqPanel when the scrollbars move. + */ + + // Set this to false to force a full panel paint + @Override + public void paintComponent(Graphics g) + { + updateViewport(); + BufferedImage lcimg = img; // take reference since other threads may null + // img and call later. + super.paintComponent(g); + + if (lcimg != null + && (fastPaint + || (getVisibleRect().width != g.getClipBounds().width) || (getVisibleRect().height != g + .getClipBounds().height))) + { + g.drawImage(lcimg, 0, 0, this); + fastPaint = false; + return; + } + + // this draws the whole of the alignment + imgWidth = getWidth(); + imgHeight = getHeight(); + + imgWidth -= (imgWidth % charWidth); + imgHeight -= (imgHeight % charHeight); + + if ((imgWidth < 1) || (imgHeight < 1)) + { + return; + } + + if (lcimg == null || imgWidth != lcimg.getWidth() + || imgHeight != lcimg.getHeight()) + { + try + { + lcimg = img = new BufferedImage(imgWidth, imgHeight, + BufferedImage.TYPE_INT_RGB); + gg = (Graphics2D) img.getGraphics(); + gg.setFont(av.getFont()); + } catch (OutOfMemoryError er) + { + System.gc(); + System.err.println("SeqCanvas OutOfMemory Redraw Error.\n" + er); + new OOMWarning("Creating alignment image for display", er); + + return; + } + } + + if (av.antiAlias) + { + gg.setRenderingHint(RenderingHints.KEY_ANTIALIASING, + RenderingHints.VALUE_ANTIALIAS_ON); + } + + gg.setColor(Color.white); + gg.fillRect(0, 0, imgWidth, imgHeight); + + if (av.getWrapAlignment()) + { + drawWrappedPanel(gg, getWidth(), getHeight(), av.startRes); + } + else + { + drawPanel(gg, av.startRes, av.endRes, av.startSeq, av.endSeq, 0); + } + + g.drawImage(lcimg, 0, 0, this); + + } + + /** + * DOCUMENT ME! + * + * @param cwidth + * DOCUMENT ME! + * + * @return DOCUMENT ME! + */ + public int getWrappedCanvasWidth(int cwidth) + { + FontMetrics fm = getFontMetrics(av.getFont()); + + LABEL_EAST = 0; + LABEL_WEST = 0; + + if (av.getScaleRightWrapped()) + { + LABEL_EAST = fm.stringWidth(getMask()); + } + + if (av.getScaleLeftWrapped()) + { + LABEL_WEST = fm.stringWidth(getMask()); + } + + return (cwidth - LABEL_EAST - LABEL_WEST) / charWidth; + } + + /** + * Generates a string of zeroes. + * + * @return String + */ + String getMask() + { + String mask = "00"; + int maxWidth = 0; + int tmp; + for (int i = 0; i < av.getAlignment().getHeight(); i++) + { + tmp = av.getAlignment().getSequenceAt(i).getEnd(); + if (tmp > maxWidth) + { + maxWidth = tmp; + } + } + + for (int i = maxWidth; i > 0; i /= 10) + { + mask += "0"; + } + return mask; + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + * @param canvasWidth + * DOCUMENT ME! + * @param canvasHeight + * DOCUMENT ME! + * @param startRes + * DOCUMENT ME! + */ + public void drawWrappedPanel(Graphics g, int canvasWidth, + int canvasHeight, int startRes) + { + updateViewport(); + AlignmentI al = av.getAlignment(); + + FontMetrics fm = getFontMetrics(av.getFont()); + + if (av.getScaleRightWrapped()) + { + LABEL_EAST = fm.stringWidth(getMask()); + } + + if (av.getScaleLeftWrapped()) + { + LABEL_WEST = fm.stringWidth(getMask()); + } + + int hgap = charHeight; + if (av.getScaleAboveWrapped()) + { + hgap += charHeight; + } + + int cWidth = (canvasWidth - LABEL_EAST - LABEL_WEST) / charWidth; + int cHeight = av.getAlignment().getHeight() * charHeight; + + av.setWrappedWidth(cWidth); + + av.endRes = av.startRes + cWidth; + + int endx; + int ypos = hgap; + int maxwidth = av.getAlignment().getWidth() - 1; + + if (av.hasHiddenColumns()) + { + maxwidth = av.getColumnSelection().findColumnPosition(maxwidth) - 1; + } + + while ((ypos <= canvasHeight) && (startRes < maxwidth)) + { + endx = startRes + cWidth - 1; + + if (endx > maxwidth) + { + endx = maxwidth; + } + + g.setFont(av.getFont()); + g.setColor(Color.black); + + if (av.getScaleLeftWrapped()) + { + drawWestScale(g, startRes, endx, ypos); + } + + if (av.getScaleRightWrapped()) + { + g.translate(canvasWidth - LABEL_EAST, 0); + drawEastScale(g, startRes, endx, ypos); + g.translate(-(canvasWidth - LABEL_EAST), 0); + } + + g.translate(LABEL_WEST, 0); + + if (av.getScaleAboveWrapped()) + { + drawNorthScale(g, startRes, endx, ypos); + } + + if (av.hasHiddenColumns() && av.getShowHiddenMarkers()) + { + g.setColor(Color.blue); + int res; + for (int i = 0; i < av.getColumnSelection().getHiddenColumns() + .size(); i++) + { + res = av.getColumnSelection().findHiddenRegionPosition(i) + - startRes; + + if (res < 0 || res > endx - startRes) + { + continue; + } + + gg.fillPolygon( + new int[] { res * charWidth - charHeight / 4, + res * charWidth + charHeight / 4, res * charWidth }, + new int[] { ypos - (charHeight / 2), + ypos - (charHeight / 2), ypos - (charHeight / 2) + 8 }, + 3); + + } + } + + // When printing we have an extra clipped region, + // the Printable page which we need to account for here + Shape clip = g.getClip(); + + if (clip == null) + { + g.setClip(0, 0, cWidth * charWidth, canvasHeight); + } + else + { + g.setClip(0, (int) clip.getBounds().getY(), cWidth * charWidth, + (int) clip.getBounds().getHeight()); + } + + drawPanel(g, startRes, endx, 0, al.getHeight(), ypos); + + if (av.isShowAnnotation()) + { + g.translate(0, cHeight + ypos + 3); + if (annotations == null) + { + annotations = new AnnotationPanel(av); + } + + annotations.renderer.drawComponent(annotations, av, g, -1, + startRes, endx + 1); + g.translate(0, -cHeight - ypos - 3); + } + g.setClip(clip); + g.translate(-LABEL_WEST, 0); + + ypos += cHeight + getAnnotationHeight() + hgap; + + startRes += cWidth; + } + } + + AnnotationPanel annotations; + + int getAnnotationHeight() + { + if (!av.isShowAnnotation()) + { + return 0; + } + + if (annotations == null) + { + annotations = new AnnotationPanel(av); + } + + return annotations.adjustPanelHeight(); + } + + /** + * DOCUMENT ME! + * + * @param g1 + * DOCUMENT ME! + * @param startRes + * DOCUMENT ME! + * @param endRes + * DOCUMENT ME! + * @param startSeq + * DOCUMENT ME! + * @param endSeq + * DOCUMENT ME! + * @param offset + * DOCUMENT ME! + */ + public void drawPanel(Graphics g1, int startRes, int endRes, + int startSeq, int endSeq, int offset) + { + updateViewport(); + if (!av.hasHiddenColumns()) + { + draw(g1, startRes, endRes, startSeq, endSeq, offset); + } + else + { + List regions = av.getColumnSelection().getHiddenColumns(); + + int screenY = 0; + int blockStart = startRes; + int blockEnd = endRes; + int newY = 0, clip; + for (int[] region : regions) + { + int hideStart = region[0]; + int hideEnd = region[1]; + + if (hideStart < blockStart) + { + blockStart += (hideEnd - hideStart) + 1; + continue; + } + blockEnd = hideStart - 1; + + g1.translate(screenY * charWidth, 0); + + // find end of this visible block + newY += blockEnd - blockStart + 1; + + clip = newY - (endRes - startRes); + if (clip > 0) + { + blockEnd = blockStart + (endRes - startRes) - screenY; + } + // TODO: JAL-1722 - does this block need clipping ? + draw(g1, blockStart, blockEnd, startSeq, endSeq, offset); + // TODO: JAL-1722 - is this hidden marker visible ? + if (clip < -1 && av.getShowHiddenMarkers()) + { + g1.setColor(Color.blue); + + g1.drawLine((blockEnd - blockStart + 1) * charWidth - 1, + 0 + offset, (blockEnd - blockStart + 1) * charWidth - 1, + (endSeq - startSeq) * charHeight + offset); + } + + g1.translate(-screenY * charWidth, 0); + + screenY = newY; + blockStart = hideEnd + 1; + + if (clip > 0) + { + // already rendered last block + return; + } + } + + if (screenY <= (endRes - startRes)) + { + // remaining visible region to render + blockEnd = blockStart + (endRes - startRes) - screenY; + g1.translate(screenY * charWidth, 0); + draw(g1, blockStart, blockEnd, startSeq, endSeq, offset); + + g1.translate(-screenY * charWidth, 0); + } + } + } + + // int startRes, int endRes, int startSeq, int endSeq, int x, int y, + // int x1, int x2, int y1, int y2, int startx, int starty, + private void draw(Graphics g, int startRes, int endRes, int startSeq, + int endSeq, int offset) + { + g.setFont(av.getFont()); + sr.prepare(g, av.isRenderGaps()); + + SequenceI nextSeq; + + // / First draw the sequences + // /////////////////////////// + for (int i = startSeq; i < endSeq; i++) + { + nextSeq = av.getAlignment().getSequenceAt(i); + if (nextSeq == null) + { + // occasionally, a race condition occurs such that the alignment row is + // empty + continue; + } + sr.drawSequence(nextSeq, av.getAlignment().findAllGroups(nextSeq), + startRes, endRes, offset + ((i - startSeq) * charHeight)); + + if (av.isShowSequenceFeatures()) + { + fr.drawSequence(g, nextSeq, startRes, endRes, offset + + ((i - startSeq) * charHeight)); + } + + // / Highlight search Results once all sequences have been drawn + // //////////////////////////////////////////////////////// + if (searchResults != null) + { + int[] visibleResults = searchResults.getResults(nextSeq, startRes, + endRes); + if (visibleResults != null) + { + for (int r = 0; r < visibleResults.length; r += 2) + { + sr.drawHighlightedText(nextSeq, visibleResults[r], + visibleResults[r + 1], (visibleResults[r] - startRes) + * charWidth, offset + + ((i - startSeq) * charHeight)); + } + } + } + + if (av.cursorMode && cursorY == i && cursorX >= startRes + && cursorX <= endRes) + { + sr.drawCursor(nextSeq, cursorX, (cursorX - startRes) * charWidth, + offset + ((i - startSeq) * charHeight)); + } + } + + if (av.getSelectionGroup() != null + || av.getAlignment().getGroups().size() > 0) + { + drawGroupsBoundaries(g, startRes, endRes, startSeq, endSeq, offset); + } + + } + + void drawGroupsBoundaries(Graphics g1, int startRes, int endRes, + int startSeq, int endSeq, int offset) + { + Graphics2D g = (Graphics2D) g1; + // + // /////////////////////////////////// + // Now outline any areas if necessary + // /////////////////////////////////// + SequenceGroup group = av.getSelectionGroup(); + + int sx = -1; + int sy = -1; + int ex = -1; + int groupIndex = -1; + int visWidth = (endRes - startRes + 1) * charWidth; + + if ((group == null) && (av.getAlignment().getGroups().size() > 0)) + { + group = av.getAlignment().getGroups().get(0); + groupIndex = 0; + } + + if (group != null) + { + do + { + int oldY = -1; + int i = 0; + boolean inGroup = false; + int top = -1; + int bottom = -1; + + for (i = startSeq; i < endSeq; i++) + { + sx = (group.getStartRes() - startRes) * charWidth; + sy = offset + ((i - startSeq) * charHeight); + ex = (((group.getEndRes() + 1) - group.getStartRes()) * charWidth) - 1; + + if (sx + ex < 0 || sx > visWidth) + { + continue; + } + + if ((sx <= (endRes - startRes) * charWidth) + && group.getSequences(null).contains( + av.getAlignment().getSequenceAt(i))) + { + if ((bottom == -1) + && !group.getSequences(null).contains( + av.getAlignment().getSequenceAt(i + 1))) + { + bottom = sy + charHeight; + } + + if (!inGroup) + { + if (((top == -1) && (i == 0)) + || !group.getSequences(null).contains( + av.getAlignment().getSequenceAt(i - 1))) + { + top = sy; + } + + oldY = sy; + inGroup = true; + + if (group == av.getSelectionGroup()) + { + g.setStroke(new BasicStroke(1, BasicStroke.CAP_BUTT, + BasicStroke.JOIN_ROUND, 3f, new float[] { 5f, 3f }, + 0f)); + g.setColor(Color.RED); + } + else + { + g.setStroke(new BasicStroke()); + g.setColor(group.getOutlineColour()); + } + } + } + else + { + if (inGroup) + { + if (sx >= 0 && sx < visWidth) + { + g.drawLine(sx, oldY, sx, sy); + } + + if (sx + ex < visWidth) + { + g.drawLine(sx + ex, oldY, sx + ex, sy); + } + + if (sx < 0) + { + ex += sx; + sx = 0; + } + + if (sx + ex > visWidth) + { + ex = visWidth; + } + + else if (sx + ex >= (endRes - startRes + 1) * charWidth) + { + ex = (endRes - startRes + 1) * charWidth; + } + + if (top != -1) + { + g.drawLine(sx, top, sx + ex, top); + top = -1; + } + + if (bottom != -1) + { + g.drawLine(sx, bottom, sx + ex, bottom); + bottom = -1; + } + + inGroup = false; + } + } + } + + if (inGroup) + { + sy = offset + ((i - startSeq) * charHeight); + if (sx >= 0 && sx < visWidth) + { + g.drawLine(sx, oldY, sx, sy); + } + + if (sx + ex < visWidth) + { + g.drawLine(sx + ex, oldY, sx + ex, sy); + } + + if (sx < 0) + { + ex += sx; + sx = 0; + } + + if (sx + ex > visWidth) + { + ex = visWidth; + } + else if (sx + ex >= (endRes - startRes + 1) * charWidth) + { + ex = (endRes - startRes + 1) * charWidth; + } + + if (top != -1) + { + g.drawLine(sx, top, sx + ex, top); + top = -1; + } + + if (bottom != -1) + { + g.drawLine(sx, bottom - 1, sx + ex, bottom - 1); + bottom = -1; + } + + inGroup = false; + } + + groupIndex++; + + g.setStroke(new BasicStroke()); + + if (groupIndex >= av.getAlignment().getGroups().size()) + { + break; + } + + group = av.getAlignment().getGroups().get(groupIndex); + + } while (groupIndex < av.getAlignment().getGroups().size()); + + } + + } + + /** + * DOCUMENT ME! + * + * @param results + * DOCUMENT ME! + */ + public void highlightSearchResults(SearchResults results) + { + img = null; + + searchResults = results; + + repaint(); + } +} diff --git a/src/jalview/gui/StructureChooser.java~ b/src/jalview/gui/StructureChooser.java~ new file mode 100644 index 0000000..5d6bef1 --- /dev/null +++ b/src/jalview/gui/StructureChooser.java~ @@ -0,0 +1,1161 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ + +package jalview.gui; + +import jalview.bin.Jalview; +import jalview.datamodel.DBRefEntry; +import jalview.datamodel.DBRefSource; +import jalview.datamodel.PDBEntry; +import jalview.datamodel.SequenceI; +import jalview.fts.api.FTSData; +import jalview.fts.api.FTSDataColumnI; +import jalview.fts.api.FTSRestClientI; +import jalview.fts.core.FTSRestRequest; +import jalview.fts.core.FTSRestResponse; +import jalview.fts.service.pdb.PDBFTSRestClient; +import jalview.jbgui.GStructureChooser; +import jalview.structure.StructureSelectionManager; +import jalview.util.MessageManager; +import jalview.ws.DBRefFetcher; +import jalview.ws.sifts.SiftsSettings; + +import java.awt.event.ItemEvent; +import java.util.ArrayList; +import java.util.Collection; +import java.util.HashSet; +import java.util.LinkedHashSet; +import java.util.List; +import java.util.Objects; +import java.util.Vector; + +import javax.swing.JCheckBox; +import javax.swing.JComboBox; +import javax.swing.JLabel; +import javax.swing.JOptionPane; +import javax.swing.table.AbstractTableModel; + +/** + * Provides the behaviors for the Structure chooser Panel + * + * @author tcnofoegbu + * + */ +@SuppressWarnings("serial") +public class StructureChooser extends GStructureChooser implements + IProgressIndicator +{ + private boolean structuresDiscovered = false; + + private SequenceI selectedSequence; + + private SequenceI[] selectedSequences; + + private IProgressIndicator progressIndicator; + + private Collection discoveredStructuresSet; + + private FTSRestRequest lastPdbRequest; + + private FTSRestClientI pdbRestCleint; + + private String selectedPdbFileName; + + private boolean isValidPBDEntry; + + public StructureChooser(SequenceI[] selectedSeqs, SequenceI selectedSeq, + AlignmentPanel ap) + { + this.ap = ap; + this.selectedSequence = selectedSeq; + this.selectedSequences = selectedSeqs; + this.progressIndicator = (ap == null) ? null : ap.alignFrame; + init(); + } + + /** + * Initializes parameters used by the Structure Chooser Panel + */ + public void init() + { + if (!Jalview.isHeadlessMode()) + { + progressBar = new ProgressBar(this.statusPanel, this.statusBar); + } + + Thread discoverPDBStructuresThread = new Thread(new Runnable() + { + @Override + public void run() + { + long startTime = System.currentTimeMillis(); + updateProgressIndicator(MessageManager + .getString("status.loading_cached_pdb_entries"), startTime); + loadLocalCachedPDBEntries(); + updateProgressIndicator(null, startTime); + updateProgressIndicator(MessageManager + .getString("status.searching_for_pdb_structures"), + startTime); + fetchStructuresMetaData(); + populateFilterComboBox(); + updateProgressIndicator(null, startTime); + mainFrame.setVisible(true); + updateCurrentView(); + } + }); + discoverPDBStructuresThread.start(); + } + + /** + * Updates the progress indicator with the specified message + * + * @param message + * displayed message for the operation + * @param id + * unique handle for this indicator + */ + public void updateProgressIndicator(String message, long id) + { + if (progressIndicator != null) + { + progressIndicator.setProgressBar(message, id); + } + } + + /** + * Retrieve meta-data for all the structure(s) for a given sequence(s) in a + * selection group + */ + public void fetchStructuresMetaData() + { + long startTime = System.currentTimeMillis(); + pdbRestCleint = PDBFTSRestClient.getInstance(); + Collection wantedFields = pdbDocFieldPrefs + .getStructureSummaryFields(); + + discoveredStructuresSet = new LinkedHashSet(); + HashSet errors = new HashSet(); + for (SequenceI seq : selectedSequences) + { + FTSRestRequest pdbRequest = new FTSRestRequest(); + pdbRequest.setAllowEmptySeq(false); + pdbRequest.setResponseSize(500); + pdbRequest.setFieldToSearchBy("("); + pdbRequest.setWantedFields(wantedFields); + pdbRequest.setSearchTerm(buildQuery(seq) + ")"); + pdbRequest.setAssociatedSequence(seq); + FTSRestResponse resultList; + try + { + resultList = pdbRestCleint.executeRequest(pdbRequest); + } catch (Exception e) + { + e.printStackTrace(); + errors.add(e.getMessage()); + continue; + } + lastPdbRequest = pdbRequest; + if (resultList.getSearchSummary() != null + && !resultList.getSearchSummary().isEmpty()) + { + discoveredStructuresSet.addAll(resultList.getSearchSummary()); + } + } + + int noOfStructuresFound = 0; + String totalTime = (System.currentTimeMillis() - startTime) + + " milli secs"; + if (discoveredStructuresSet != null + && !discoveredStructuresSet.isEmpty()) + { + getResultTable().setModel( + FTSRestResponse.getTableModel(lastPdbRequest, + discoveredStructuresSet)); + structuresDiscovered = true; + noOfStructuresFound = discoveredStructuresSet.size(); + mainFrame.setTitle(MessageManager.formatMessage( + "label.structure_chooser_no_of_structures", + noOfStructuresFound, totalTime)); + } + else + { + mainFrame.setTitle(MessageManager + .getString("label.structure_chooser_manual_association")); + if (errors.size() > 0) + { + StringBuilder errorMsg = new StringBuilder(); + for (String error : errors) + { + errorMsg.append(error).append("\n"); + } + JOptionPane.showMessageDialog(this, errorMsg.toString(), + MessageManager.getString("label.pdb_web-service_error"), + JOptionPane.ERROR_MESSAGE); + } + } + } + + public void loadLocalCachedPDBEntries() + { + ArrayList entries = new ArrayList(); + for (SequenceI seq : selectedSequences) + { + if (seq.getDatasetSequence() != null + && seq.getDatasetSequence().getAllPDBEntries() != null) + { + for (PDBEntry pdbEntry : seq.getDatasetSequence() + .getAllPDBEntries()) + { + if (pdbEntry.getFile() != null) + { + entries.add(new CachedPDB(seq, pdbEntry)); + } + } + } + } + + PDBEntryTableModel tableModelx = new PDBEntryTableModel(entries); + tbl_local_pdb.setModel(tableModelx); + } + + /** + * Builds a query string for a given sequences using its DBRef entries + * + * @param seq + * the sequences to build a query for + * @return the built query string + */ + + public static String buildQuery(SequenceI seq) + { + boolean isPDBRefsFound = false; + boolean isUniProtRefsFound = false; + StringBuilder queryBuilder = new StringBuilder(); + HashSet seqRefs = new LinkedHashSet(); + + if (seq.getAllPDBEntries() != null) + { + for (PDBEntry entry : seq.getAllPDBEntries()) + { + if (isValidSeqName(entry.getId())) + { + queryBuilder.append("pdb_id") + .append(":") +.append(entry.getId().toLowerCase()) + .append(" OR "); + isPDBRefsFound = true; + // seqRefs.add(entry.getId()); + } + } + } + + if (seq.getDBRefs() != null && seq.getDBRefs().length != 0) + { + for (DBRefEntry dbRef : seq.getDBRefs()) + { + if (isValidSeqName(getDBRefId(dbRef))) + { + if (dbRef.getSource().equalsIgnoreCase(DBRefSource.UNIPROT)) + { + queryBuilder +.append("uniprot_accession").append(":") + .append(getDBRefId(dbRef)) + .append(" OR "); + queryBuilder +.append("uniprot_id") + .append(":") + .append(getDBRefId(dbRef)).append(" OR "); + isUniProtRefsFound = true; + } + else if (dbRef.getSource().equalsIgnoreCase(DBRefSource.PDB)) + { + + queryBuilder.append("pdb_id") + .append(":").append(getDBRefId(dbRef).toLowerCase()) + .append(" OR "); + isPDBRefsFound = true; + } + else + { + seqRefs.add(getDBRefId(dbRef)); + } + } + } + } + + if (!isPDBRefsFound && !isUniProtRefsFound) + { + String seqName = seq.getName(); + seqName = sanitizeSeqName(seqName); + String[] names = seqName.toLowerCase().split("\\|"); + for (String name : names) + { + // System.out.println("Found name : " + name); + name.trim(); + if (isValidSeqName(name)) + { + seqRefs.add(name); + } + } + + for (String seqRef : seqRefs) + { + queryBuilder.append("text:").append(seqRef).append(" OR "); + } + } + + int endIndex = queryBuilder.lastIndexOf(" OR "); + if (queryBuilder.toString().length() < 6) + { + return null; + } + String query = queryBuilder.toString().substring(0, endIndex); + return query; + } + + /** + * Remove the following special characters from input string +, -, &, !, (, ), + * {, }, [, ], ^, ", ~, *, ?, :, \ + * + * @param seqName + * @return + */ + static String sanitizeSeqName(String seqName) + { + Objects.requireNonNull(seqName); + return seqName.replaceAll("\\[\\d*\\]", "") + .replaceAll("[^\\dA-Za-z|_]", "").replaceAll("\\s+", "+"); + } + + + /** + * Ensures sequence ref names are not less than 3 characters and does not + * contain a database name + * + * @param seqName + * @return + */ + public static boolean isValidSeqName(String seqName) + { + // System.out.println("seqName : " + seqName); + String ignoreList = "pdb,uniprot,swiss-prot"; + if (seqName.length() < 3) + { + return false; + } + if (seqName.contains(":")) + { + return false; + } + seqName = seqName.toLowerCase(); + for (String ignoredEntry : ignoreList.split(",")) + { + if (seqName.contains(ignoredEntry)) + { + return false; + } + } + return true; + } + + public static String getDBRefId(DBRefEntry dbRef) + { + String ref = dbRef.getAccessionId().replaceAll("GO:", ""); + return ref; + } + + /** + * Filters a given list of discovered structures based on supplied argument + * + * @param fieldToFilterBy + * the field to filter by + */ + public void filterResultSet(final String fieldToFilterBy) + { + Thread filterThread = new Thread(new Runnable() + { + @Override + public void run() + { + long startTime = System.currentTimeMillis(); + pdbRestCleint = PDBFTSRestClient.getInstance(); + lbl_loading.setVisible(true); + Collection wantedFields = pdbDocFieldPrefs + .getStructureSummaryFields(); + Collection filteredResponse = new HashSet(); + HashSet errors = new HashSet(); + + for (SequenceI seq : selectedSequences) + { + FTSRestRequest pdbRequest = new FTSRestRequest(); + if (fieldToFilterBy.equalsIgnoreCase("uniprot_coverage")) + { + pdbRequest.setAllowEmptySeq(false); + pdbRequest.setResponseSize(1); + pdbRequest.setFieldToSearchBy("("); + pdbRequest.setSearchTerm(buildQuery(seq) + ")"); + pdbRequest.setWantedFields(wantedFields); + pdbRequest.setAssociatedSequence(seq); + pdbRequest.setFacet(true); + pdbRequest.setFacetPivot(fieldToFilterBy + ",entry_entity"); + pdbRequest.setFacetPivotMinCount(1); + } + else + { + pdbRequest.setAllowEmptySeq(false); + pdbRequest.setResponseSize(1); + pdbRequest.setFieldToSearchBy("("); + pdbRequest.setFieldToSortBy(fieldToFilterBy, + !chk_invertFilter.isSelected()); + pdbRequest.setSearchTerm(buildQuery(seq) + ")"); + pdbRequest.setWantedFields(wantedFields); + pdbRequest.setAssociatedSequence(seq); + } + FTSRestResponse resultList; + try + { + resultList = pdbRestCleint.executeRequest(pdbRequest); + } catch (Exception e) + { + e.printStackTrace(); + errors.add(e.getMessage()); + continue; + } + lastPdbRequest = pdbRequest; + if (resultList.getSearchSummary() != null + && !resultList.getSearchSummary().isEmpty()) + { + filteredResponse.addAll(resultList.getSearchSummary()); + } + } + + String totalTime = (System.currentTimeMillis() - startTime) + + " milli secs"; + if (!filteredResponse.isEmpty()) + { + final int filterResponseCount = filteredResponse.size(); + Collection reorderedStructuresSet = new LinkedHashSet(); + reorderedStructuresSet.addAll(filteredResponse); + reorderedStructuresSet.addAll(discoveredStructuresSet); + getResultTable().setModel( + FTSRestResponse.getTableModel( + lastPdbRequest, reorderedStructuresSet)); + + FTSRestResponse.configureTableColumn(getResultTable(), + wantedFields); + getResultTable().getColumn("Ref Sequence").setPreferredWidth(120); + getResultTable().getColumn("Ref Sequence").setMinWidth(100); + getResultTable().getColumn("Ref Sequence").setMaxWidth(200); + // Update table selection model here + getResultTable().addRowSelectionInterval(0, + filterResponseCount - 1); + mainFrame.setTitle(MessageManager.formatMessage( + "label.structure_chooser_filter_time", totalTime)); + } + else + { + mainFrame.setTitle(MessageManager.formatMessage( + "label.structure_chooser_filter_time", totalTime)); + if (errors.size() > 0) + { + StringBuilder errorMsg = new StringBuilder(); + for (String error : errors) + { + errorMsg.append(error).append("\n"); + } + JOptionPane.showMessageDialog( + null, + errorMsg.toString(), + MessageManager.getString("label.pdb_web-service_error"), + JOptionPane.ERROR_MESSAGE); + } + } + + lbl_loading.setVisible(false); + + validateSelections(); + } + }); + filterThread.start(); + } + + /** + * Handles action event for btn_pdbFromFile + */ + @Override + public void pdbFromFile_actionPerformed() + { + jalview.io.JalviewFileChooser chooser = new jalview.io.JalviewFileChooser( + jalview.bin.Cache.getProperty("LAST_DIRECTORY")); + chooser.setFileView(new jalview.io.JalviewFileView()); + chooser.setDialogTitle(MessageManager.formatMessage( + "label.select_pdb_file_for", + selectedSequence.getDisplayId(false))); + chooser.setToolTipText(MessageManager.formatMessage( + "label.load_pdb_file_associate_with_sequence", + selectedSequence.getDisplayId(false))); + + int value = chooser.showOpenDialog(null); + if (value == jalview.io.JalviewFileChooser.APPROVE_OPTION) + { + selectedPdbFileName = chooser.getSelectedFile().getPath(); + jalview.bin.Cache.setProperty("LAST_DIRECTORY", selectedPdbFileName); + validateSelections(); + } + } + + /** + * Populates the filter combo-box options dynamically depending on discovered + * structures + */ + @Override + protected void populateFilterComboBox() + { + if (isStructuresDiscovered()) + { + cmb_filterOption.addItem(new FilterOption("Best Quality", + "overall_quality", VIEWS_FILTER)); + cmb_filterOption.addItem(new FilterOption("Best Resolution", + "resolution", VIEWS_FILTER)); + cmb_filterOption.addItem(new FilterOption("Most Protein Chain", + "number_of_protein_chains", VIEWS_FILTER)); + cmb_filterOption.addItem(new FilterOption("Most Bound Molecules", + "number_of_bound_molecules", VIEWS_FILTER)); + cmb_filterOption.addItem(new FilterOption("Most Polymer Residues", + "number_of_polymer_residues", VIEWS_FILTER)); + } + cmb_filterOption.addItem(new FilterOption("Enter PDB Id", "-", + VIEWS_ENTER_ID)); + cmb_filterOption.addItem(new FilterOption("From File", "-", + VIEWS_FROM_FILE)); + cmb_filterOption.addItem(new FilterOption("Cached PDB Entries", "-", + VIEWS_LOCAL_PDB)); + } + + /** + * Updates the displayed view based on the selected filter option + */ + @Override + protected void updateCurrentView() + { + FilterOption selectedFilterOpt = ((FilterOption) cmb_filterOption + .getSelectedItem()); + layout_switchableViews.show(pnl_switchableViews, + selectedFilterOpt.getView()); + String filterTitle = mainFrame.getTitle(); + mainFrame.setTitle(frameTitle); + chk_invertFilter.setVisible(false); + if (selectedFilterOpt.getView() == VIEWS_FILTER) + { + mainFrame.setTitle(filterTitle); + chk_invertFilter.setVisible(true); + filterResultSet(selectedFilterOpt.getValue()); + } + else if (selectedFilterOpt.getView() == VIEWS_ENTER_ID + || selectedFilterOpt.getView() == VIEWS_FROM_FILE) + { + mainFrame.setTitle(MessageManager + .getString("label.structure_chooser_manual_association")); + idInputAssSeqPanel.loadCmbAssSeq(); + fileChooserAssSeqPanel.loadCmbAssSeq(); + } + validateSelections(); + } + + /** + * Validates user selection and activates the view button if all parameters + * are correct + */ + @Override + public void validateSelections() + { + FilterOption selectedFilterOpt = ((FilterOption) cmb_filterOption + .getSelectedItem()); + btn_view.setEnabled(false); + String currentView = selectedFilterOpt.getView(); + if (currentView == VIEWS_FILTER) + { + if (getResultTable().getSelectedRows().length > 0) + { + btn_view.setEnabled(true); + } + } + else if (currentView == VIEWS_LOCAL_PDB) + { + if (tbl_local_pdb.getSelectedRows().length > 0) + { + btn_view.setEnabled(true); + } + } + else if (currentView == VIEWS_ENTER_ID) + { + validateAssociationEnterPdb(); + } + else if (currentView == VIEWS_FROM_FILE) + { + validateAssociationFromFile(); + } + } + + /** + * Validates inputs from the Manual PDB entry panel + */ + public void validateAssociationEnterPdb() + { + AssociateSeqOptions assSeqOpt = (AssociateSeqOptions) idInputAssSeqPanel + .getCmb_assSeq().getSelectedItem(); + lbl_pdbManualFetchStatus.setIcon(errorImage); + lbl_pdbManualFetchStatus.setToolTipText(""); + if (txt_search.getText().length() > 0) + { + lbl_pdbManualFetchStatus + .setToolTipText(JvSwingUtils.wrapTooltip(true, MessageManager + .formatMessage("info.no_pdb_entry_found_for", + txt_search.getText()))); + } + + if (errorWarning.length() > 0) + { + lbl_pdbManualFetchStatus.setIcon(warningImage); + lbl_pdbManualFetchStatus.setToolTipText(JvSwingUtils.wrapTooltip( + true, errorWarning.toString())); + } + + if (selectedSequences.length == 1 + || !assSeqOpt.getName().equalsIgnoreCase( + "-Select Associated Seq-")) + { + txt_search.setEnabled(true); + if (isValidPBDEntry) + { + btn_view.setEnabled(true); + lbl_pdbManualFetchStatus.setToolTipText(""); + lbl_pdbManualFetchStatus.setIcon(goodImage); + } + } + else + { + txt_search.setEnabled(false); + lbl_pdbManualFetchStatus.setIcon(errorImage); + } + } + + /** + * Validates inputs for the manual PDB file selection options + */ + public void validateAssociationFromFile() + { + AssociateSeqOptions assSeqOpt = (AssociateSeqOptions) fileChooserAssSeqPanel + .getCmb_assSeq().getSelectedItem(); + lbl_fromFileStatus.setIcon(errorImage); + if (selectedSequences.length == 1 + || (assSeqOpt != null && !assSeqOpt.getName().equalsIgnoreCase( + "-Select Associated Seq-"))) + { + btn_pdbFromFile.setEnabled(true); + if (selectedPdbFileName != null && selectedPdbFileName.length() > 0) + { + btn_view.setEnabled(true); + lbl_fromFileStatus.setIcon(goodImage); + } + } + else + { + btn_pdbFromFile.setEnabled(false); + lbl_fromFileStatus.setIcon(errorImage); + } + } + + @Override + public void cmbAssSeqStateChanged() + { + validateSelections(); + } + + /** + * Handles the state change event for the 'filter' combo-box and 'invert' + * check-box + */ + @Override + protected void stateChanged(ItemEvent e) + { + if (e.getSource() instanceof JCheckBox) + { + updateCurrentView(); + } + else + { + if (e.getStateChange() == ItemEvent.SELECTED) + { + updateCurrentView(); + } + } + + } + + /** + * Handles action event for btn_ok + */ + @Override + public void ok_ActionPerformed() + { + final StructureSelectionManager ssm = ap.getStructureSelectionManager(); + new Thread(new Runnable() + { + @Override + public void run() + { + FilterOption selectedFilterOpt = ((FilterOption) cmb_filterOption + .getSelectedItem()); + String currentView = selectedFilterOpt.getView(); + if (currentView == VIEWS_FILTER) + { + int pdbIdColIndex = getResultTable().getColumn("PDB Id") + .getModelIndex(); + int refSeqColIndex = getResultTable().getColumn("Ref Sequence") + .getModelIndex(); + int[] selectedRows = getResultTable().getSelectedRows(); + PDBEntry[] pdbEntriesToView = new PDBEntry[selectedRows.length]; + int count = 0; + ArrayList selectedSeqsToView = new ArrayList(); + for (int row : selectedRows) + { + String pdbIdStr = getResultTable().getValueAt(row, + pdbIdColIndex) + .toString(); + SequenceI selectedSeq = (SequenceI) getResultTable() + .getValueAt(row, + refSeqColIndex); + selectedSeqsToView.add(selectedSeq); + PDBEntry pdbEntry = selectedSeq.getPDBEntry(pdbIdStr); + if (pdbEntry == null) + { + pdbEntry = getFindEntry(pdbIdStr, + selectedSeq.getAllPDBEntries()); + } + if (pdbEntry == null) + { + pdbEntry = new PDBEntry(); + pdbEntry.setId(pdbIdStr); + pdbEntry.setType(PDBEntry.Type.PDB); + selectedSeq.getDatasetSequence().addPDBId(pdbEntry); + } + pdbEntriesToView[count++] = pdbEntry; + } + SequenceI[] selectedSeqs = selectedSeqsToView + .toArray(new SequenceI[selectedSeqsToView.size()]); + launchStructureViewer(ssm, pdbEntriesToView, ap, + selectedSeqs); + } + else if (currentView == VIEWS_LOCAL_PDB) + { + int[] selectedRows = tbl_local_pdb.getSelectedRows(); + PDBEntry[] pdbEntriesToView = new PDBEntry[selectedRows.length]; + int count = 0; + int pdbIdColIndex = tbl_local_pdb.getColumn("PDB Id") + .getModelIndex(); + int refSeqColIndex = tbl_local_pdb.getColumn("Ref Sequence") + .getModelIndex(); + ArrayList selectedSeqsToView = new ArrayList(); + for (int row : selectedRows) + { + PDBEntry pdbEntry = (PDBEntry) tbl_local_pdb.getValueAt(row, + pdbIdColIndex); + pdbEntriesToView[count++] = pdbEntry; + SequenceI selectedSeq = (SequenceI) tbl_local_pdb.getValueAt(row, + refSeqColIndex); + selectedSeqsToView.add(selectedSeq); + } + SequenceI[] selectedSeqs = selectedSeqsToView + .toArray(new SequenceI[selectedSeqsToView.size()]); + launchStructureViewer(ssm, pdbEntriesToView, ap, + selectedSeqs); + } + else if (currentView == VIEWS_ENTER_ID) + { + SequenceI userSelectedSeq = ((AssociateSeqOptions) idInputAssSeqPanel + .getCmb_assSeq().getSelectedItem()).getSequence(); + if (userSelectedSeq != null) + { + selectedSequence = userSelectedSeq; + } + + String pdbIdStr = txt_search.getText(); + PDBEntry pdbEntry = selectedSequence.getPDBEntry(pdbIdStr); + if (pdbEntry == null) + { + pdbEntry = new PDBEntry(); + if (pdbIdStr.split(":").length > 1) + { + pdbEntry.setChainCode(pdbIdStr.split(":")[1]); + } + pdbEntry.setId(pdbIdStr); + pdbEntry.setType(PDBEntry.Type.PDB); + selectedSequence.getDatasetSequence().addPDBId(pdbEntry); + } + + PDBEntry[] pdbEntriesToView = new PDBEntry[] { pdbEntry }; + launchStructureViewer(ssm, pdbEntriesToView, ap, + new SequenceI[] { selectedSequence }); + } + else if (currentView == VIEWS_FROM_FILE) + { + SequenceI userSelectedSeq = ((AssociateSeqOptions) fileChooserAssSeqPanel + .getCmb_assSeq().getSelectedItem()).getSequence(); + if (userSelectedSeq != null) + { + selectedSequence = userSelectedSeq; + } + PDBEntry fileEntry = new AssociatePdbFileWithSeq() + .associatePdbWithSeq(selectedPdbFileName, + jalview.io.AppletFormatAdapter.FILE, + selectedSequence, true, Desktop.instance); + + launchStructureViewer(ssm, + new PDBEntry[] { fileEntry }, ap, + new SequenceI[] { selectedSequence }); + } + mainFrame.dispose(); + } + }).start(); + } + + private PDBEntry getFindEntry(String id, Vector pdbEntries) + { + Objects.requireNonNull(id); + Objects.requireNonNull(pdbEntries); + PDBEntry foundEntry = null; + for (PDBEntry entry : pdbEntries) + { + if (entry.getId().equalsIgnoreCase(id)) + { + return entry; + } + } + return foundEntry; + } + + private void launchStructureViewer(StructureSelectionManager ssm, + final PDBEntry[] pdbEntriesToView, + final AlignmentPanel alignPanel, SequenceI[] sequences) + { + long progressId = sequences.hashCode(); + setProgressBar(MessageManager + .getString("status.launching_3d_structure_viewer"), progressId); + final StructureViewer sViewer = new StructureViewer(ssm); + setProgressBar(null, progressId); + + if (SiftsSettings.isMapWithSifts()) + { + // TODO: prompt user if there are lots of sequences without dbrefs. + // It can take a long time if we need to fetch all dbrefs for all + // sequences! + ArrayList seqsWithoutSourceDBRef = new ArrayList(); + for (SequenceI seq : sequences) + { + if (seq.getSourceDBRef() == null && seq.getDBRefs() == null) + { + seqsWithoutSourceDBRef.add(seq); + continue; + } + } + if (!seqsWithoutSourceDBRef.isEmpty()) + { + int y = seqsWithoutSourceDBRef.size(); + setProgressBar(MessageManager.formatMessage( + "status.fetching_dbrefs_for_sequences_without_valid_refs", + y, + progressId); + SequenceI[] seqWithoutSrcDBRef = new SequenceI[y]; + int x = 0; + for (SequenceI fSeq : seqsWithoutSourceDBRef) + { + seqWithoutSrcDBRef[x++] = fSeq; + } + new DBRefFetcher(seqWithoutSrcDBRef).fetchDBRefs(true); + setProgressBar("Fetch complete.", progressId); // todo i18n + } + } + if (pdbEntriesToView.length > 1) + { + ArrayList seqsMap = new ArrayList(); + for (SequenceI seq : sequences) + { + seqsMap.add(new SequenceI[] { seq }); + } + SequenceI[][] collatedSeqs = seqsMap.toArray(new SequenceI[0][0]); +<<<<<<< Updated upstream + ssm.setProgressBar(null); + ssm.setProgressBar(MessageManager + .getString("status.fetching_3d_structures_for_selected_entries")); +======= + setProgressBar("Fetching structure data", progressId); +>>>>>>> Stashed changes + sViewer.viewStructures(pdbEntriesToView, collatedSeqs, alignPanel); + } + else + { +<<<<<<< Updated upstream + ssm.setProgressBar(null); + ssm.setProgressBar(MessageManager.formatMessage( + "status.fetching_3d_structures_for", + pdbEntriesToView[0].getId())); +======= + setProgressBar( + "Fetching structure for " + pdbEntriesToView[0].getId(), + progressId); +>>>>>>> Stashed changes + sViewer.viewStructures(pdbEntriesToView[0], sequences, alignPanel); + } + setProgressBar(null, progressId); + } + + /** + * Populates the combo-box used in associating manually fetched structures to + * a unique sequence when more than one sequence selection is made. + */ + @Override + public void populateCmbAssociateSeqOptions( + JComboBox cmb_assSeq, JLabel lbl_associateSeq) + { + cmb_assSeq.removeAllItems(); + cmb_assSeq.addItem(new AssociateSeqOptions("-Select Associated Seq-", + null)); + lbl_associateSeq.setVisible(false); + if (selectedSequences.length > 1) + { + for (SequenceI seq : selectedSequences) + { + cmb_assSeq.addItem(new AssociateSeqOptions(seq)); + } + } + else + { + String seqName = selectedSequence.getDisplayId(false); + seqName = seqName.length() <= 40 ? seqName : seqName.substring(0, 39); + lbl_associateSeq.setText(seqName); + lbl_associateSeq.setVisible(true); + cmb_assSeq.setVisible(false); + } + } + + public boolean isStructuresDiscovered() + { + return structuresDiscovered; + } + + public void setStructuresDiscovered(boolean structuresDiscovered) + { + this.structuresDiscovered = structuresDiscovered; + } + + public Collection getDiscoveredStructuresSet() + { + return discoveredStructuresSet; + } + + @Override + protected void txt_search_ActionPerformed() + { + new Thread() + { + @Override + public void run() + { + errorWarning.setLength(0); + isValidPBDEntry = false; + if (txt_search.getText().length() > 0) + { + String searchTerm = txt_search.getText().toLowerCase(); + searchTerm = searchTerm.split(":")[0]; + // System.out.println(">>>>> search term : " + searchTerm); + List wantedFields = new ArrayList(); + FTSRestRequest pdbRequest = new FTSRestRequest(); + pdbRequest.setAllowEmptySeq(false); + pdbRequest.setResponseSize(1); + pdbRequest.setFieldToSearchBy("(pdb_id:"); + pdbRequest.setWantedFields(wantedFields); + pdbRequest +.setSearchTerm(searchTerm + ")"); + pdbRequest.setAssociatedSequence(selectedSequence); + pdbRestCleint = PDBFTSRestClient.getInstance(); + wantedFields.add(pdbRestCleint.getPrimaryKeyColumn()); + FTSRestResponse resultList; + try + { + resultList = pdbRestCleint.executeRequest(pdbRequest); + } catch (Exception e) + { + errorWarning.append(e.getMessage()); + return; + } finally + { + validateSelections(); + } + if (resultList.getSearchSummary() != null + && resultList.getSearchSummary().size() > 0) + { + isValidPBDEntry = true; + } + } + validateSelections(); + } + }.start(); + } + + @Override + public void tabRefresh() + { + if (selectedSequences != null) + { + Thread refreshThread = new Thread(new Runnable() + { + @Override + public void run() + { + fetchStructuresMetaData(); + filterResultSet(((FilterOption) cmb_filterOption + .getSelectedItem()).getValue()); + } + }); + refreshThread.start(); + } + } + + public class PDBEntryTableModel extends AbstractTableModel + { + String[] columns = { "Ref Sequence", "PDB Id", "Chain", "Type", "File" }; + + private List pdbEntries; + + public PDBEntryTableModel(List pdbEntries) + { + this.pdbEntries = new ArrayList(pdbEntries); + } + + @Override + public String getColumnName(int columnIndex) + { + return columns[columnIndex]; + } + + @Override + public int getRowCount() + { + return pdbEntries.size(); + } + + @Override + public int getColumnCount() + { + return columns.length; + } + + @Override + public boolean isCellEditable(int row, int column) + { + return false; + } + + @Override + public Object getValueAt(int rowIndex, int columnIndex) + { + Object value = "??"; + CachedPDB entry = pdbEntries.get(rowIndex); + switch (columnIndex) + { + case 0: + value = entry.getSequence(); + break; + case 1: + value = entry.getPdbEntry(); + break; + case 2: + value = entry.getPdbEntry().getChainCode() == null ? "_" : entry + .getPdbEntry().getChainCode(); + break; + case 3: + value = entry.getPdbEntry().getType(); + break; + case 4: + value = entry.getPdbEntry().getFile(); + break; + } + return value; + } + + @Override + public Class getColumnClass(int columnIndex) + { + return columnIndex == 0 ? SequenceI.class : PDBEntry.class; + } + + public CachedPDB getPDBEntryAt(int row) + { + return pdbEntries.get(row); + } + + } + + private class CachedPDB + { + private SequenceI sequence; + + private PDBEntry pdbEntry; + + public CachedPDB(SequenceI sequence, PDBEntry pdbEntry) + { + this.sequence = sequence; + this.pdbEntry = pdbEntry; + } + + public SequenceI getSequence() + { + return sequence; + } + + public PDBEntry getPdbEntry() + { + return pdbEntry; + } + + } + + private IProgressIndicator progressBar; + + @Override + public void setProgressBar(String message, long id) + { + progressBar.setProgressBar(message, id); + } + + @Override + public void registerHandler(long id, IProgressIndicatorHandler handler) + { + progressBar.registerHandler(id, handler); + } + + @Override + public boolean operationInProgress() + { + return progressBar.operationInProgress(); + } +} diff --git a/src/jalview/gui/TreeCanvas.java~ b/src/jalview/gui/TreeCanvas.java~ new file mode 100755 index 0000000..90c74be --- /dev/null +++ b/src/jalview/gui/TreeCanvas.java~ @@ -0,0 +1,1080 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.gui; + +import jalview.analysis.Conservation; +import jalview.analysis.NJTree; +import jalview.api.AlignViewportI; +import jalview.datamodel.Sequence; +import jalview.datamodel.SequenceGroup; +import jalview.datamodel.SequenceI; +import jalview.datamodel.SequenceNode; +import jalview.schemes.ColourSchemeI; +import jalview.schemes.ColourSchemeProperty; +import jalview.schemes.ResidueProperties; +import jalview.schemes.UserColourScheme; +import jalview.structure.SelectionSource; +import jalview.util.Format; +import jalview.util.MappingUtils; +import jalview.util.MessageManager; + +import java.awt.Color; +import java.awt.Dimension; +import java.awt.Font; +import java.awt.FontMetrics; +import java.awt.Graphics; +import java.awt.Graphics2D; +import java.awt.Point; +import java.awt.Rectangle; +import java.awt.RenderingHints; +import java.awt.event.MouseEvent; +import java.awt.event.MouseListener; +import java.awt.event.MouseMotionListener; +import java.awt.print.PageFormat; +import java.awt.print.Printable; +import java.awt.print.PrinterException; +import java.awt.print.PrinterJob; +import java.util.Enumeration; +import java.util.Hashtable; +import java.util.Vector; + +import javax.swing.JColorChooser; +import javax.swing.JPanel; +import javax.swing.JScrollPane; +import javax.swing.SwingUtilities; +import javax.swing.ToolTipManager; + +/** + * DOCUMENT ME! + * + * @author $author$ + * @version $Revision$ + */ +public class TreeCanvas extends JPanel implements MouseListener, Runnable, + Printable, MouseMotionListener, SelectionSource +{ + /** DOCUMENT ME!! */ + public static final String PLACEHOLDER = " * "; + + NJTree tree; + + JScrollPane scrollPane; + + TreePanel tp; + + AlignViewport av; + + AlignmentPanel ap; + + Font font; + + FontMetrics fm; + + boolean fitToWindow = true; + + boolean showDistances = false; + + boolean showBootstrap = false; + + boolean markPlaceholders = false; + + int offx = 20; + + int offy; + + float threshold; + + String longestName; + + int labelLength = -1; + + Hashtable nameHash = new Hashtable(); + + Hashtable nodeHash = new Hashtable(); + + SequenceNode highlightNode; + + boolean applyToAllViews = false; + + /** + * Creates a new TreeCanvas object. + * + * @param av + * DOCUMENT ME! + * @param tree + * DOCUMENT ME! + * @param scroller + * DOCUMENT ME! + * @param label + * DOCUMENT ME! + */ + public TreeCanvas(TreePanel tp, AlignmentPanel ap, JScrollPane scroller) + { + this.tp = tp; + this.av = ap.av; + this.ap = ap; + font = av.getFont(); + scrollPane = scroller; + addMouseListener(this); + addMouseMotionListener(this); + ToolTipManager.sharedInstance().registerComponent(this); + } + + /** + * DOCUMENT ME! + * + * @param sequence + * DOCUMENT ME! + */ + public void treeSelectionChanged(SequenceI sequence) + { + AlignmentPanel[] aps = getAssociatedPanels(); + + for (int a = 0; a < aps.length; a++) + { + SequenceGroup selected = aps[a].av.getSelectionGroup(); + + if (selected == null) + { + selected = new SequenceGroup(); + aps[a].av.setSelectionGroup(selected); + } + + selected.setEndRes(aps[a].av.getAlignment().getWidth() - 1); + selected.addOrRemove(sequence, true); + } + } + + /** + * DOCUMENT ME! + * + * @param tree + * DOCUMENT ME! + */ + public void setTree(NJTree tree) + { + this.tree = tree; + tree.findHeight(tree.getTopNode()); + + // Now have to calculate longest name based on the leaves + Vector leaves = tree.findLeaves(tree.getTopNode(), new Vector()); + boolean has_placeholders = false; + longestName = ""; + + for (int i = 0; i < leaves.size(); i++) + { + SequenceNode lf = (SequenceNode) leaves.elementAt(i); + + if (lf.isPlaceholder()) + { + has_placeholders = true; + } + + if (longestName.length() < ((Sequence) lf.element()).getName() + .length()) + { + longestName = TreeCanvas.PLACEHOLDER + + ((Sequence) lf.element()).getName(); + } + } + + setMarkPlaceholders(has_placeholders); + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + * @param node + * DOCUMENT ME! + * @param chunk + * DOCUMENT ME! + * @param scale + * DOCUMENT ME! + * @param width + * DOCUMENT ME! + * @param offx + * DOCUMENT ME! + * @param offy + * DOCUMENT ME! + */ + public void drawNode(Graphics g, SequenceNode node, float chunk, + float scale, int width, int offx, int offy) + { + if (node == null) + { + return; + } + + if ((node.left() == null) && (node.right() == null)) + { + // Drawing leaf node + float height = node.height; + float dist = node.dist; + + int xstart = (int) ((height - dist) * scale) + offx; + int xend = (int) (height * scale) + offx; + + int ypos = (int) (node.ycount * chunk) + offy; + + if (node.element() instanceof SequenceI) + { + SequenceI seq = (SequenceI) node.element(); + + if (av.getSequenceColour(seq) == Color.white) + { + g.setColor(Color.black); + } + else + { + g.setColor(av.getSequenceColour(seq).darker()); + } + } + else + { + g.setColor(Color.black); + } + + // Draw horizontal line + g.drawLine(xstart, ypos, xend, ypos); + + String nodeLabel = ""; + + if (showDistances && (node.dist > 0)) + { + nodeLabel = new Format("%-.2f").form(node.dist); + } + + if (showBootstrap && node.bootstrap > -1) + { + if (showDistances) + { + nodeLabel = nodeLabel + " : "; + } + + nodeLabel = nodeLabel + String.valueOf(node.bootstrap); + } + + if (!nodeLabel.equals("")) + { + g.drawString(nodeLabel, xstart + 2, ypos - 2); + } + + String name = (markPlaceholders && node.isPlaceholder()) ? (PLACEHOLDER + node + .getName()) : node.getName(); + + int charWidth = fm.stringWidth(name) + 3; + int charHeight = font.getSize(); + + Rectangle rect = new Rectangle(xend + 10, ypos - charHeight / 2, + charWidth, charHeight); + + nameHash.put(node.element(), rect); + + // Colour selected leaves differently + SequenceGroup selected = av.getSelectionGroup(); + + if ((selected != null) + && selected.getSequences(null).contains(node.element())) + { + g.setColor(Color.gray); + + g.fillRect(xend + 10, ypos - charHeight / 2, charWidth, charHeight); + g.setColor(Color.white); + } + + g.drawString(name, xend + 10, ypos + fm.getDescent()); + g.setColor(Color.black); + } + else + { + drawNode(g, (SequenceNode) node.left(), chunk, scale, width, offx, + offy); + drawNode(g, (SequenceNode) node.right(), chunk, scale, width, offx, + offy); + + float height = node.height; + float dist = node.dist; + + int xstart = (int) ((height - dist) * scale) + offx; + int xend = (int) (height * scale) + offx; + int ypos = (int) (node.ycount * chunk) + offy; + + g.setColor(node.color.darker()); + + // Draw horizontal line + g.drawLine(xstart, ypos, xend, ypos); + if (node == highlightNode) + { + g.fillRect(xend - 3, ypos - 3, 6, 6); + } + else + { + g.fillRect(xend - 2, ypos - 2, 4, 4); + } + + int ystart = (int) (((SequenceNode) node.left()).ycount * chunk) + + offy; + int yend = (int) (((SequenceNode) node.right()).ycount * chunk) + + offy; + + Rectangle pos = new Rectangle(xend - 2, ypos - 2, 5, 5); + nodeHash.put(node, pos); + + g.drawLine((int) (height * scale) + offx, ystart, + (int) (height * scale) + offx, yend); + + String nodeLabel = ""; + + if (showDistances && (node.dist > 0)) + { + nodeLabel = new Format("%-.2f").form(node.dist); + } + + if (showBootstrap && node.bootstrap > -1) + { + if (showDistances) + { + nodeLabel = nodeLabel + " : "; + } + + nodeLabel = nodeLabel + String.valueOf(node.bootstrap); + } + + if (!nodeLabel.equals("")) + { + g.drawString(nodeLabel, xstart + 2, ypos - 2); + } + } + } + + /** + * DOCUMENT ME! + * + * @param x + * DOCUMENT ME! + * @param y + * DOCUMENT ME! + * + * @return DOCUMENT ME! + */ + public Object findElement(int x, int y) + { + Enumeration keys = nameHash.keys(); + + while (keys.hasMoreElements()) + { + Object ob = keys.nextElement(); + Rectangle rect = (Rectangle) nameHash.get(ob); + + if ((x >= rect.x) && (x <= (rect.x + rect.width)) && (y >= rect.y) + && (y <= (rect.y + rect.height))) + { + return ob; + } + } + + keys = nodeHash.keys(); + + while (keys.hasMoreElements()) + { + Object ob = keys.nextElement(); + Rectangle rect = (Rectangle) nodeHash.get(ob); + + if ((x >= rect.x) && (x <= (rect.x + rect.width)) && (y >= rect.y) + && (y <= (rect.y + rect.height))) + { + return ob; + } + } + + return null; + } + + /** + * DOCUMENT ME! + * + * @param pickBox + * DOCUMENT ME! + */ + public void pickNodes(Rectangle pickBox) + { + int width = getWidth(); + int height = getHeight(); + + SequenceNode top = tree.getTopNode(); + + float wscale = (float) ((width * .8) - (offx * 2)) + / tree.getMaxHeight(); + + if (top.count == 0) + { + top.count = ((SequenceNode) top.left()).count + + ((SequenceNode) top.right()).count; + } + + float chunk = (float) (height - (offy)) / top.count; + + pickNode(pickBox, top, chunk, wscale, width, offx, offy); + } + + /** + * DOCUMENT ME! + * + * @param pickBox + * DOCUMENT ME! + * @param node + * DOCUMENT ME! + * @param chunk + * DOCUMENT ME! + * @param scale + * DOCUMENT ME! + * @param width + * DOCUMENT ME! + * @param offx + * DOCUMENT ME! + * @param offy + * DOCUMENT ME! + */ + public void pickNode(Rectangle pickBox, SequenceNode node, float chunk, + float scale, int width, int offx, int offy) + { + if (node == null) + { + return; + } + + if ((node.left() == null) && (node.right() == null)) + { + float height = node.height; + float dist = node.dist; + + int xstart = (int) ((height - dist) * scale) + offx; + int xend = (int) (height * scale) + offx; + + int ypos = (int) (node.ycount * chunk) + offy; + + if (pickBox.contains(new Point(xend, ypos))) + { + if (node.element() instanceof SequenceI) + { + SequenceI seq = (SequenceI) node.element(); + SequenceGroup sg = av.getSelectionGroup(); + + if (sg != null) + { + sg.addOrRemove(seq, true); + } + } + } + } + else + { + pickNode(pickBox, (SequenceNode) node.left(), chunk, scale, width, + offx, offy); + pickNode(pickBox, (SequenceNode) node.right(), chunk, scale, width, + offx, offy); + } + } + + /** + * DOCUMENT ME! + * + * @param node + * DOCUMENT ME! + * @param c + * DOCUMENT ME! + */ + public void setColor(SequenceNode node, Color c) + { + if (node == null) + { + return; + } + + if ((node.left() == null) && (node.right() == null)) // TODO: internal node + { + node.color = c; + + if (node.element() instanceof SequenceI) + { + AlignmentPanel[] aps = getAssociatedPanels(); + if (aps != null) + { + for (int a = 0; a < aps.length; a++) + { + final SequenceI seq = (SequenceI) node.element(); + aps[a].av.setSequenceColour(seq, c); + } + } + } + } + else + { + node.color = c; + setColor((SequenceNode) node.left(), c); + setColor((SequenceNode) node.right(), c); + } + } + + /** + * DOCUMENT ME! + */ + void startPrinting() + { + Thread thread = new Thread(this); + thread.start(); + } + + // put printing in a thread to avoid painting problems + @Override + public void run() + { + PrinterJob printJob = PrinterJob.getPrinterJob(); + PageFormat pf = printJob.pageDialog(printJob.defaultPage()); + + printJob.setPrintable(this, pf); + + if (printJob.printDialog()) + { + try + { + printJob.print(); + } catch (Exception PrintException) + { + PrintException.printStackTrace(); + } + } + } + + /** + * DOCUMENT ME! + * + * @param pg + * DOCUMENT ME! + * @param pf + * DOCUMENT ME! + * @param pi + * DOCUMENT ME! + * + * @return DOCUMENT ME! + * + * @throws PrinterException + * DOCUMENT ME! + */ + @Override + public int print(Graphics pg, PageFormat pf, int pi) + throws PrinterException + { + pg.setFont(font); + pg.translate((int) pf.getImageableX(), (int) pf.getImageableY()); + + int pwidth = (int) pf.getImageableWidth(); + int pheight = (int) pf.getImageableHeight(); + + int noPages = getHeight() / pheight; + + if (pi > noPages) + { + return Printable.NO_SUCH_PAGE; + } + + if (pwidth > getWidth()) + { + pwidth = getWidth(); + } + + if (fitToWindow) + { + if (pheight > getHeight()) + { + pheight = getHeight(); + } + + noPages = 0; + } + else + { + FontMetrics fm = pg.getFontMetrics(font); + int height = fm.getHeight() * nameHash.size(); + pg.translate(0, -pi * pheight); + pg.setClip(0, pi * pheight, pwidth, (pi * pheight) + pheight); + + // translate number of pages, + // height is screen size as this is the + // non overlapping text size + pheight = height; + } + + draw(pg, pwidth, pheight); + + return Printable.PAGE_EXISTS; + } + + /** + * DOCUMENT ME! + * + * @param g + * DOCUMENT ME! + */ + @Override + public void paintComponent(Graphics g) + { + super.paintComponent(g); + g.setFont(font); + + if (tree == null) + { + g.drawString(MessageManager.getString("label.calculating_tree") + + "....", 20, getHeight() / 2); + } + else + { + fm = g.getFontMetrics(font); + + if (nameHash.size() == 0) + { + repaint(); + } + + if (fitToWindow + || (!fitToWindow && (scrollPane.getHeight() > ((fm + .getHeight() * nameHash.size()) + offy)))) + { + draw(g, scrollPane.getWidth(), scrollPane.getHeight()); + setPreferredSize(null); + } + else + { + setPreferredSize(new Dimension(scrollPane.getWidth(), + fm.getHeight() * nameHash.size())); + draw(g, scrollPane.getWidth(), fm.getHeight() * nameHash.size()); + } + + scrollPane.revalidate(); + } + } + + /** + * DOCUMENT ME! + * + * @param fontSize + * DOCUMENT ME! + */ + @Override + public void setFont(Font font) + { + this.font = font; + repaint(); + } + + /** + * DOCUMENT ME! + * + * @param g1 + * DOCUMENT ME! + * @param width + * DOCUMENT ME! + * @param height + * DOCUMENT ME! + */ + public void draw(Graphics g1, int width, int height) + { + Graphics2D g2 = (Graphics2D) g1; + g2.setRenderingHint(RenderingHints.KEY_ANTIALIASING, + RenderingHints.VALUE_ANTIALIAS_ON); + g2.setColor(Color.white); + g2.fillRect(0, 0, width, height); + g2.setFont(font); + + if (longestName == null || tree == null) + { + g2.drawString("Calculating tree.", 20, 20); + } + offy = font.getSize() + 10; + + fm = g2.getFontMetrics(font); + + labelLength = fm.stringWidth(longestName) + 20; // 20 allows for scrollbar + + float wscale = (width - labelLength - (offx * 2)) / tree.getMaxHeight(); + + SequenceNode top = tree.getTopNode(); + + if (top.count == 0) + { + top.count = ((SequenceNode) top.left()).count + + ((SequenceNode) top.right()).count; + } + + float chunk = (float) (height - (offy)) / top.count; + + drawNode(g2, tree.getTopNode(), chunk, wscale, width, offx, offy); + + if (threshold != 0) + { + if (av.getCurrentTree() == tree) + { + g2.setColor(Color.red); + } + else + { + g2.setColor(Color.gray); + } + + int x = (int) ((threshold * (getWidth() - labelLength - (2 * offx))) + offx); + + g2.drawLine(x, 0, x, getHeight()); + } + } + + /** + * DOCUMENT ME! + * + * @param e + * DOCUMENT ME! + */ + @Override + public void mouseReleased(MouseEvent e) + { + } + + /** + * DOCUMENT ME! + * + * @param e + * DOCUMENT ME! + */ + @Override + public void mouseEntered(MouseEvent e) + { + } + + /** + * DOCUMENT ME! + * + * @param e + * DOCUMENT ME! + */ + @Override + public void mouseExited(MouseEvent e) + { + } + + /** + * DOCUMENT ME! + * + * @param e + * DOCUMENT ME! + */ + @Override + public void mouseClicked(MouseEvent evt) + { + if (highlightNode != null) + { + if (SwingUtilities.isRightMouseButton(evt)) + { + Color col = JColorChooser.showDialog(this, + MessageManager.getString("label.select_subtree_colour"), + highlightNode.color); + if (col != null) + { + setColor(highlightNode, col); + } + } + else if (evt.getClickCount() > 1) + { + tree.swapNodes(highlightNode); + tree.reCount(tree.getTopNode()); + tree.findHeight(tree.getTopNode()); + } + else + { + Vector leaves = new Vector(); + tree.findLeaves(highlightNode, leaves); + + for (int i = 0; i < leaves.size(); i++) + { + SequenceI seq = (SequenceI) ((SequenceNode) leaves.elementAt(i)) + .element(); + treeSelectionChanged(seq); + } + av.sendSelection(); + } + + PaintRefresher.Refresh(tp, av.getSequenceSetId()); + repaint(); + } + } + + @Override + public void mouseMoved(MouseEvent evt) + { + av.setCurrentTree(tree); + + Object ob = findElement(evt.getX(), evt.getY()); + + if (ob instanceof SequenceNode) + { + highlightNode = (SequenceNode) ob; + this.setToolTipText("" + + MessageManager.getString("label.highlightnode")); + repaint(); + + } + else + { + if (highlightNode != null) + { + highlightNode = null; + setToolTipText(null); + repaint(); + } + } + } + + @Override + public void mouseDragged(MouseEvent ect) + { + } + + /** + * DOCUMENT ME! + * + * @param e + * DOCUMENT ME! + */ + @Override + public void mousePressed(MouseEvent e) + { + av.setCurrentTree(tree); + + int x = e.getX(); + int y = e.getY(); + + Object ob = findElement(x, y); + + if (ob instanceof SequenceI) + { + treeSelectionChanged((Sequence) ob); + PaintRefresher.Refresh(tp, ap.av.getSequenceSetId()); + repaint(); + av.sendSelection(); + return; + } + else if (!(ob instanceof SequenceNode)) + { + // Find threshold + if (tree.getMaxHeight() != 0) + { + threshold = (float) (x - offx) + / (float) (getWidth() - labelLength - (2 * offx)); + + tree.getGroups().removeAllElements(); + tree.groupNodes(tree.getTopNode(), threshold); + setColor(tree.getTopNode(), Color.black); + + AlignmentPanel[] aps = getAssociatedPanels(); + + // TODO push calls below into a single AlignViewportI method? + // see also AlignViewController.deleteGroups + for (int a = 0; a < aps.length; a++) + { + aps[a].av.setSelectionGroup(null); + aps[a].av.getAlignment().deleteAllGroups(); + aps[a].av.clearSequenceColours(); + if (aps[a].av.getCodingComplement() != null) + { + aps[a].av.getCodingComplement().setSelectionGroup(null); + aps[a].av.getCodingComplement().getAlignment() + .deleteAllGroups(); + aps[a].av.getCodingComplement().clearSequenceColours(); + } + } + colourGroups(); + } + + PaintRefresher.Refresh(tp, ap.av.getSequenceSetId()); + repaint(); + } + + } + + void colourGroups() + { + AlignmentPanel[] aps = getAssociatedPanels(); + for (int i = 0; i < tree.getGroups().size(); i++) + { + Color col = new Color((int) (Math.random() * 255), + (int) (Math.random() * 255), (int) (Math.random() * 255)); + setColor((SequenceNode) tree.getGroups().elementAt(i), col.brighter()); + + Vector l = tree.findLeaves( + (SequenceNode) tree.getGroups().elementAt(i), new Vector()); + + Vector sequences = new Vector(); + + for (int j = 0; j < l.size(); j++) + { + SequenceI s1 = (SequenceI) ((SequenceNode) l.elementAt(j)) + .element(); + + if (!sequences.contains(s1)) + { + sequences.addElement(s1); + } + } + + ColourSchemeI cs = null; + SequenceGroup sg = new SequenceGroup(sequences, null, cs, true, true, + false, 0, av.getAlignment().getWidth() - 1); + + if (av.getGlobalColourScheme() != null) + { + if (av.getGlobalColourScheme() instanceof UserColourScheme) + { + cs = new UserColourScheme( + ((UserColourScheme) av.getGlobalColourScheme()) + .getColours()); + + } + else + { + cs = ColourSchemeProperty.getColour(sg, ColourSchemeProperty + .getColourName(av.getGlobalColourScheme())); + } + // cs is null if shading is an annotationColourGradient + if (cs != null) + { + cs.setThreshold(av.getGlobalColourScheme().getThreshold(), + av.isIgnoreGapsConsensus()); + } + } + sg.cs = cs; + // sg.recalcConservation(); + sg.setName("JTreeGroup:" + sg.hashCode()); + sg.setIdColour(col); + + for (int a = 0; a < aps.length; a++) + { + if (aps[a].av.getGlobalColourScheme() != null + && aps[a].av.getGlobalColourScheme().conservationApplied()) + { + Conservation c = new Conservation("Group", + ResidueProperties.propHash, 3, sg.getSequences(null), + sg.getStartRes(), sg.getEndRes()); + + c.calculate(); + c.verdict(false, aps[a].av.getConsPercGaps()); + sg.cs.setConservation(c); + } + + aps[a].av.getAlignment().addGroup(new SequenceGroup(sg)); + // TODO can we push all of the below into AlignViewportI? + final AlignViewportI codingComplement = aps[a].av + .getCodingComplement(); + if (codingComplement != null) + { + if (codingComplement != null) + { + SequenceGroup mappedGroup = MappingUtils.mapSequenceGroup(sg, + av, codingComplement); + if (mappedGroup.getSequences().size() > 0) + { + codingComplement.getAlignment().addGroup(mappedGroup); + for (SequenceI seq : mappedGroup.getSequences()) + { + codingComplement.setSequenceColour(seq, col.brighter()); + } + } + } + } + } + } + + // notify the panel(s) to redo any group specific stuff. + for (int a = 0; a < aps.length; a++) + { + aps[a].updateAnnotation(); + // TODO: JAL-868 - need to ensure view colour change message is broadcast + // to any Jmols listening in + final AlignViewportI codingComplement = aps[a].av + .getCodingComplement(); + if (codingComplement != null) + { + ((AlignViewport) codingComplement).getAlignPanel() + .updateAnnotation(); + + } + + } + + } + + /** + * DOCUMENT ME! + * + * @param state + * DOCUMENT ME! + */ + public void setShowDistances(boolean state) + { + this.showDistances = state; + repaint(); + } + + /** + * DOCUMENT ME! + * + * @param state + * DOCUMENT ME! + */ + public void setShowBootstrap(boolean state) + { + this.showBootstrap = state; + repaint(); + } + + /** + * DOCUMENT ME! + * + * @param state + * DOCUMENT ME! + */ + public void setMarkPlaceholders(boolean state) + { + this.markPlaceholders = state; + repaint(); + } + + AlignmentPanel[] getAssociatedPanels() + { + if (applyToAllViews) + { + return PaintRefresher.getAssociatedPanels(av.getSequenceSetId()); + } + else + { + return new AlignmentPanel[] { ap }; + } + } +} diff --git a/src/jalview/io/AppletFormatAdapter.java b/src/jalview/io/AppletFormatAdapter.java index 00fcb9c..5de14a4 100755 --- a/src/jalview/io/AppletFormatAdapter.java +++ b/src/jalview/io/AppletFormatAdapter.java @@ -28,6 +28,7 @@ import jalview.datamodel.Alignment; import jalview.datamodel.AlignmentAnnotation; import jalview.datamodel.AlignmentI; import jalview.datamodel.AlignmentView; +import jalview.datamodel.SeqDistanceContactMatrix; import jalview.datamodel.PDBEntry.Type; import jalview.datamodel.SequenceI; import jalview.ext.jmol.JmolParser; diff --git a/src/jalview/io/PContactPredictionFile.java b/src/jalview/io/PContactPredictionFile.java new file mode 100644 index 0000000..92500c0 --- /dev/null +++ b/src/jalview/io/PContactPredictionFile.java @@ -0,0 +1,136 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.io; + +import jalview.datamodel.ContactMatrix; +import jalview.datamodel.SequenceI; + +import java.io.IOException; +import java.util.ArrayList; +import java.util.HashMap; +import java.util.List; +import java.util.Map; + +/** + * A file parser for contact prediction files. + * + * An example file is the following + * + * 

+ * 
+ *
+ * + * + * @author jim procter + * + */ +public class PContactPredictionFile extends AlignFile +{ + public PContactPredictionFile(String inFile, DataSourceType fileSourceType) + throws IOException + { + super(inFile, fileSourceType); + + } + + public PContactPredictionFile(FileParse source) throws IOException + { + super(source); + } + + Integer fWidth; + + List models = new ArrayList(); + + public List getContactMatrices() + { + return models; + } + + /* + * RaptorX pattern: + * for a contact prediction + * Target sequence + * alignment for target sequence + * contact matrix for sequence + * models generated that fit matrix + */ + + /* + * TODO: create annotation rows from contact matrices. + * (non-Javadoc) + * @see jalview.io.AlignFile#parse() + */ + @Override + public void parse() throws IOException + { + String line; + /* + * stash any header lines if we've been given a CASP-RR file + */ + Map header = new HashMap(); + ContactMatrix cm = null; + + while ((line = nextLine()) != null) + { + int left, right; + double strength = Float.NaN; + String parts[] = line.split("\\s+"); + + // check for header tokens in parts[0] + + // others - stash details + // MODEL - start a new matrix + // skip comments ? + + if (parts.length == 3) // and all are integers + { + + if (cm == null) + { + cm = new ContactMatrix(true); + models.add(cm); + } + + try + { + left = Integer.parseInt(parts[0]); + right = Integer.parseInt(parts[1]); + strength = Double.parseDouble(parts[2]); + } catch (Exception x) + { + error = true; + errormessage = "Couldn't process line: " + + x.getLocalizedMessage() + "\n" + line; + return; + } + cm.addContact(left, right, (float) strength); + } + } + } + + @Override + public String print(SequenceI[] sqs, boolean jvsuffix) + { + // TODO Auto-generated method stub + return "Not valid."; + } +} diff --git a/src/jalview/renderer/AnnotationRenderer.java b/src/jalview/renderer/AnnotationRenderer.java index be4f497..eb83f31 100644 --- a/src/jalview/renderer/AnnotationRenderer.java +++ b/src/jalview/renderer/AnnotationRenderer.java @@ -30,6 +30,8 @@ import jalview.datamodel.Annotation; import jalview.datamodel.ColumnSelection; import jalview.datamodel.HiddenColumns; import jalview.datamodel.ProfilesI; +import jalview.renderer.api.AnnotationRendererFactoryI; +import jalview.renderer.api.AnnotationRowRendererI; import jalview.schemes.ColourSchemeI; import jalview.schemes.NucleotideColourScheme; import jalview.schemes.ResidueProperties; @@ -155,6 +157,7 @@ public class AnnotationRenderer hStrucConsensus = null; fadedImage = null; annotationPanel = null; + rendererFactoryI = null; } void drawStemAnnot(Graphics g, Annotation[] row_annotations, int lastSSX, @@ -313,6 +316,7 @@ public class AnnotationRenderer useClip = false; } + rendererFactoryI = AnnotationRendererFactory.getRendererFactory(); updateFromAlignViewport(av); } @@ -417,6 +421,10 @@ public class AnnotationRenderer return null; } + boolean rna = false; + + private AnnotationRendererFactoryI rendererFactoryI; + /** * Render the annotation rows associated with an alignment. * @@ -1063,6 +1071,32 @@ public class AnnotationRenderer row.graphMin, row.graphMax, y, renderHistogram, renderProfile, normaliseProfile); } + else + { + AnnotationRowRendererI renderer = rendererFactoryI + .getRendererFor(row); + if (renderer != null) + { + renderer.renderRow(g, charWidth, charHeight, + hasHiddenColumns, av, hiddenColumns, columnSelection, + row, row_annotations, startRes, endRes, row.graphMin, + row.graphMax, y); + } + if (debugRedraw) + { + if (renderer == null) + { + System.err.println("No renderer found for " + + row.toString()); + } + else + { + System.err.println("rendered with " + + renderer.getClass().toString()); + } + } + + } } } else diff --git a/src/jalview/renderer/AnnotationRendererFactory.java b/src/jalview/renderer/AnnotationRendererFactory.java new file mode 100644 index 0000000..1bee418 --- /dev/null +++ b/src/jalview/renderer/AnnotationRendererFactory.java @@ -0,0 +1,41 @@ +package jalview.renderer; + +import jalview.datamodel.AlignmentAnnotation; +import jalview.renderer.api.AnnotationRendererFactoryI; +import jalview.renderer.api.AnnotationRowRendererI; + +import java.util.IdentityHashMap; + +public class AnnotationRendererFactory implements + AnnotationRendererFactoryI +{ + + private static AnnotationRendererFactoryI factory = null; + + public static AnnotationRendererFactoryI getRendererFactory() + { + if (factory == null) + { + factory = new AnnotationRendererFactory(); + } + return factory; + } + + IdentityHashMap renderers = new IdentityHashMap(); + + public AnnotationRendererFactory() + { + // renderers.put) + } + + @Override + public AnnotationRowRendererI getRendererFor(AlignmentAnnotation row) + { + if (row.graph == AlignmentAnnotation.CUSTOMRENDERER) + { + return new ContactMapRenderer(); + } + return null; + } + +} diff --git a/src/jalview/renderer/ContactMapRenderer.java b/src/jalview/renderer/ContactMapRenderer.java new file mode 100644 index 0000000..c9198ed --- /dev/null +++ b/src/jalview/renderer/ContactMapRenderer.java @@ -0,0 +1,122 @@ +/** + * + */ +package jalview.renderer; + +import jalview.api.AlignViewportI; +import jalview.datamodel.AlignmentAnnotation; +import jalview.datamodel.Annotation; +import jalview.datamodel.ColumnSelection; +import jalview.datamodel.ContactListI; +import jalview.datamodel.ContactRange; +import jalview.datamodel.HiddenColumns; +import jalview.renderer.api.AnnotationRowRendererI; + +import java.awt.Color; +import java.awt.Graphics; + +/** + * @author jprocter + * + */ +public class ContactMapRenderer implements AnnotationRowRendererI +{ + + @Override + public void renderRow(Graphics g, int charWidth, int charHeight, + boolean hasHiddenColumns, AlignViewportI viewport, HiddenColumns hiddenColumns, + ColumnSelection columnSelection, AlignmentAnnotation _aa, + Annotation[] aa_annotations, int sRes, int eRes, float min, + float max, int y) + { + if (sRes > aa_annotations.length) + { + return; + } + eRes = Math.min(eRes, aa_annotations.length); + + int x = 0, y2 = y; + + g.setColor(Color.pink); + + g.drawLine(x, y2, (eRes - sRes) * charWidth, y2); + + int column; + int aaMax = aa_annotations.length - 1; + while (x < eRes - sRes) + { + column = sRes + x; + if (hasHiddenColumns) + { + column = hiddenColumns.visibleToAbsoluteColumn(column); + } + + if (column > aaMax) + { + break; + } + + if (aa_annotations[column] == null) + { + x++; + continue; + } + /* + * {profile type, #values, total count, char1, pct1, char2, pct2...} + */ + ContactListI contacts = viewport.getContactList(_aa, column); + if (contacts == null) + { + return; + } + int contact_height = contacts.getContactHeight(); + // fractional pixel height to render each contact cell + double pixels_per_contact = ((double) _aa.graphHeight) + / (double) contact_height; + // fractional number of contacts covering each pixel + double contacts_per_pixel = 1d/pixels_per_contact; + // number of contacts to render at a time + int step = (pixels_per_contact<1) ? (int) Math.floor(contacts_per_pixel) : (int) Math.ceil(pixels_per_contact); + + int pixels_step = (int) Math.ceil(step*pixels_per_contact); + int cstart, cend = -1; + for (int ht = y2, eht = y2 - _aa.graphHeight; ht >= eht; ht -= pixels_step) + { + cstart = cend + 1; + cend = (int) Math.min(contact_height, cstart + step); + // TODO show maximum colour for range - sort of done + // also need a 'getMaxPosForRange(start,end)' + g.setColor(getColorForRange(min, max, contacts, cstart, cend)); + + if (pixels_step>1) + { + g.fillRect(x * charWidth, ht, charWidth, 1 + (int) pixels_step); + } + else + { + g.drawLine(x * charWidth, ht, (x + 1) * charWidth, ht); + } + } + x++; + } + + } + + Color minColor = Color.white, maxColor = Color.magenta; + + + Color shadeFor(float min, float max, float value) + { + return jalview.util.ColorUtils.getGraduatedColour(value, 0, minColor, + max, maxColor); + } + + public Color getColorForRange(float min, float max, ContactListI cl, + int i, int j) + { + ContactRange cr = cl.getRangeFor(i, j); + // average for moment - probably more interested in maxIntProj though + return shadeFor(min, max, (float) cr.getMean()); + } + +} diff --git a/src/jalview/renderer/api/AnnotationRendererFactoryI.java b/src/jalview/renderer/api/AnnotationRendererFactoryI.java new file mode 100644 index 0000000..a78c391 --- /dev/null +++ b/src/jalview/renderer/api/AnnotationRendererFactoryI.java @@ -0,0 +1,10 @@ +package jalview.renderer.api; + +import jalview.datamodel.AlignmentAnnotation; + +public interface AnnotationRendererFactoryI +{ + + AnnotationRowRendererI getRendererFor(AlignmentAnnotation row); + +} diff --git a/src/jalview/renderer/api/AnnotationRowRendererI.java b/src/jalview/renderer/api/AnnotationRowRendererI.java new file mode 100644 index 0000000..bedbad5 --- /dev/null +++ b/src/jalview/renderer/api/AnnotationRowRendererI.java @@ -0,0 +1,21 @@ +package jalview.renderer.api; + +import jalview.api.AlignViewportI; +import jalview.datamodel.AlignmentAnnotation; +import jalview.datamodel.Annotation; +import jalview.datamodel.ColumnSelection; +import jalview.datamodel.HiddenColumns; + +import java.awt.Graphics; + +public interface AnnotationRowRendererI +{ + + void renderRow(Graphics g, int charWidth, int charHeight, + boolean hasHiddenColumns, AlignViewportI av, + HiddenColumns hiddenColumns, + ColumnSelection columnSelection, AlignmentAnnotation row, + Annotation[] row_annotations, int startRes, int endRes, + float graphMin, float graphMax, int y); + +} diff --git a/src/jalview/structure/StructureSelectionManager.java~ b/src/jalview/structure/StructureSelectionManager.java~ new file mode 100644 index 0000000..5b06097 --- /dev/null +++ b/src/jalview/structure/StructureSelectionManager.java~ @@ -0,0 +1,1327 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.structure; + +import jalview.analysis.AlignSeq; +import jalview.api.StructureSelectionManagerProvider; +import jalview.commands.CommandI; +import jalview.commands.EditCommand; +import jalview.commands.OrderCommand; +import jalview.datamodel.AlignedCodonFrame; +import jalview.datamodel.AlignmentAnnotation; +import jalview.datamodel.AlignmentI; +import jalview.datamodel.Annotation; +import jalview.datamodel.PDBEntry; +import jalview.datamodel.SearchResults; +import jalview.datamodel.SequenceI; +import jalview.gui.IProgressIndicator; +import jalview.io.AppletFormatAdapter; +import jalview.io.StructureFile; +import jalview.util.MappingUtils; +import jalview.util.MessageManager; +import jalview.ws.sifts.SiftsClient; +import jalview.ws.sifts.SiftsException; +import jalview.ws.sifts.SiftsSettings; + +import java.io.PrintStream; +import java.util.ArrayList; +import java.util.Arrays; +import java.util.Collections; +import java.util.Enumeration; +import java.util.HashMap; +import java.util.IdentityHashMap; +import java.util.List; +import java.util.Map; +import java.util.Vector; + +import MCview.Atom; +import MCview.PDBChain; +import MCview.PDBfile; + +public class StructureSelectionManager +{ + public final static String NEWLINE = System.lineSeparator(); + + static IdentityHashMap instances; + + private List mappings = new ArrayList(); + + private boolean processSecondaryStructure = false; + + private boolean secStructServices = false; + + private boolean addTempFacAnnot = false; + + private SiftsClient siftsClient = null; + + /* + * Set of any registered mappings between (dataset) sequences. + */ + private List seqmappings = new ArrayList(); + + private List commandListeners = new ArrayList(); + + private List sel_listeners = new ArrayList(); + + /** + * @return true if will try to use external services for processing secondary + * structure + */ + public boolean isSecStructServices() + { + return secStructServices; + } + + /** + * control use of external services for processing secondary structure + * + * @param secStructServices + */ + public void setSecStructServices(boolean secStructServices) + { + this.secStructServices = secStructServices; + } + + /** + * flag controlling addition of any kind of structural annotation + * + * @return true if temperature factor annotation will be added + */ + public boolean isAddTempFacAnnot() + { + return addTempFacAnnot; + } + + /** + * set flag controlling addition of structural annotation + * + * @param addTempFacAnnot + */ + public void setAddTempFacAnnot(boolean addTempFacAnnot) + { + this.addTempFacAnnot = addTempFacAnnot; + } + + /** + * + * @return if true, the structure manager will attempt to add secondary + * structure lines for unannotated sequences + */ + + public boolean isProcessSecondaryStructure() + { + return processSecondaryStructure; + } + + /** + * Control whether structure manager will try to annotate mapped sequences + * with secondary structure from PDB data. + * + * @param enable + */ + public void setProcessSecondaryStructure(boolean enable) + { + processSecondaryStructure = enable; + } + + /** + * debug function - write all mappings to stdout + */ + public void reportMapping() + { + if (mappings.isEmpty()) + { + System.err.println("reportMapping: No PDB/Sequence mappings."); + } + else + { + System.err.println("reportMapping: There are " + mappings.size() + + " mappings."); + int i = 0; + for (StructureMapping sm : mappings) + { + System.err.println("mapping " + i++ + " : " + sm.pdbfile); + } + } + } + + /** + * map between the PDB IDs (or structure identifiers) used by Jalview and the + * absolute filenames for PDB data that corresponds to it + */ + Map pdbIdFileName = new HashMap(); + + Map pdbFileNameId = new HashMap(); + + public void registerPDBFile(String idForFile, String absoluteFile) + { + pdbIdFileName.put(idForFile, absoluteFile); + pdbFileNameId.put(absoluteFile, idForFile); + } + + public String findIdForPDBFile(String idOrFile) + { + String id = pdbFileNameId.get(idOrFile); + return id; + } + + public String findFileForPDBId(String idOrFile) + { + String id = pdbIdFileName.get(idOrFile); + return id; + } + + public boolean isPDBFileRegistered(String idOrFile) + { + return pdbFileNameId.containsKey(idOrFile) + || pdbIdFileName.containsKey(idOrFile); + } + + private static StructureSelectionManager nullProvider = null; + + public static StructureSelectionManager getStructureSelectionManager( + StructureSelectionManagerProvider context) + { + if (context == null) + { + if (nullProvider == null) + { + if (instances != null) + { + throw new Error( + MessageManager + .getString("error.implementation_error_structure_selection_manager_null"), + new NullPointerException(MessageManager + .getString("exception.ssm_context_is_null"))); + } + else + { + nullProvider = new StructureSelectionManager(); + } + return nullProvider; + } + } + if (instances == null) + { + instances = new java.util.IdentityHashMap(); + } + StructureSelectionManager instance = instances.get(context); + if (instance == null) + { + if (nullProvider != null) + { + instance = nullProvider; + } + else + { + instance = new StructureSelectionManager(); + } + instances.put(context, instance); + } + return instance; + } + + /** + * flag controlling whether SeqMappings are relayed from received sequence + * mouse over events to other sequences + */ + boolean relaySeqMappings = true; + + /** + * Enable or disable relay of seqMapping events to other sequences. You might + * want to do this if there are many sequence mappings and the host computer + * is slow + * + * @param relay + */ + public void setRelaySeqMappings(boolean relay) + { + relaySeqMappings = relay; + } + + /** + * get the state of the relay seqMappings flag. + * + * @return true if sequence mouse overs are being relayed to other mapped + * sequences + */ + public boolean isRelaySeqMappingsEnabled() + { + return relaySeqMappings; + } + + Vector listeners = new Vector(); + + /** + * register a listener for alignment sequence mouseover events + * + * @param svl + */ + public void addStructureViewerListener(Object svl) + { + if (!listeners.contains(svl)) + { + listeners.addElement(svl); + } + } + + /** + * Returns the file name for a mapped PDB id (or null if not mapped). + * + * @param pdbid + * @return + */ + public String alreadyMappedToFile(String pdbid) + { + for (StructureMapping sm : mappings) + { + if (sm.getPdbId().equals(pdbid)) + { + return sm.pdbfile; + } + } + return null; + } + + /** + * Import structure data and register a structure mapping for broadcasting + * colouring, mouseovers and selection events (convenience wrapper). + * + * @param sequence + * - one or more sequences to be mapped to pdbFile + * @param targetChains + * - optional chain specification for mapping each sequence to pdb + * (may be nill, individual elements may be nill) + * @param pdbFile + * - structure data resource + * @param protocol + * - how to resolve data from resource + * @return null or the structure data parsed as a pdb file + */ + synchronized public StructureFile setMapping(SequenceI[] sequence, + String[] targetChains, String pdbFile, String protocol, + IProgressIndicator progress) + { + return computeMapping(true, sequence, targetChains, pdbFile, protocol, + progress); + } + + + /** + * create sequence structure mappings between each sequence and the given + * pdbFile (retrieved via the given protocol). + * + * @param forStructureView + * when true, record the mapping for use in mouseOvers + * + * @param sequenceArray + * - one or more sequences to be mapped to pdbFile + * @param targetChainIds + * - optional chain specification for mapping each sequence to pdb + * (may be null, individual elements may be null) + * @param pdbFile + * - structure data resource + * @param protocol + * - how to resolve data from resource + * @return null or the structure data parsed as a pdb file + */ + synchronized public StructureFile setMapping(boolean forStructureView, + SequenceI[] sequenceArray, String[] targetChainIds, + String pdbFile, + String protocol) + { + return computeMapping(forStructureView, sequenceArray, targetChainIds, + pdbFile, protocol, null); + } + + synchronized public StructureFile computeMapping( + boolean forStructureView, SequenceI[] sequenceArray, + String[] targetChainIds, String pdbFile, String protocol, + IProgressIndicator progress) + { + long progressSessionId = System.currentTimeMillis() * 3; + /* + * There will be better ways of doing this in the future, for now we'll use + * the tried and tested MCview pdb mapping + */ + boolean parseSecStr = processSecondaryStructure; + if (isPDBFileRegistered(pdbFile)) + { + for (SequenceI sq : sequenceArray) + { + SequenceI ds = sq; + while (ds.getDatasetSequence() != null) + { + ds = ds.getDatasetSequence(); + } + ; + if (ds.getAnnotation() != null) + { + for (AlignmentAnnotation ala : ds.getAnnotation()) + { + // false if any annotation present from this structure + // JBPNote this fails for jmol/chimera view because the *file* is + // passed, not the structure data ID - + if (PDBfile.isCalcIdForFile(ala, findIdForPDBFile(pdbFile))) + { + parseSecStr = false; + } + } + } + } + } + StructureFile pdb = null; + boolean isMapUsingSIFTs = SiftsSettings.isMapWithSifts(); + try + { + + if (pdbFile != null && isCIFFile(pdbFile)) + { + pdb = new jalview.ext.jmol.JmolParser(addTempFacAnnot, parseSecStr, + secStructServices, pdbFile, protocol); + } + else + { + pdb = new PDBfile(addTempFacAnnot, parseSecStr, secStructServices, + pdbFile, protocol); + } + + if (pdb.getId() != null && pdb.getId().trim().length() > 0 + && AppletFormatAdapter.FILE.equals(protocol)) + { + registerPDBFile(pdb.getId().trim(), pdbFile); + } + } catch (Exception ex) + { + ex.printStackTrace(); + return null; + } + + try + { + if (isMapUsingSIFTs) + { + siftsClient = new SiftsClient(pdb); + } + } catch (SiftsException e) + { + isMapUsingSIFTs = false; + e.printStackTrace(); + } + + String targetChainId; + for (int s = 0; s < sequenceArray.length; s++) + { + boolean infChain = true; + final SequenceI seq = sequenceArray[s]; + if (targetChainIds != null && targetChainIds[s] != null) + { + infChain = false; + targetChainId = targetChainIds[s]; + } + else if (seq.getName().indexOf("|") > -1) + { + targetChainId = seq.getName().substring( + seq.getName().lastIndexOf("|") + 1); + if (targetChainId.length() > 1) + { + if (targetChainId.trim().length() == 0) + { + targetChainId = " "; + } + else + { + // not a valid chain identifier + targetChainId = ""; + } + } + } + else + { + targetChainId = ""; + } + + /* + * Attempt pairwise alignment of the sequence with each chain in the PDB, + * and remember the highest scoring chain + */ + int max = -10; + AlignSeq maxAlignseq = null; + String maxChainId = " "; + PDBChain maxChain = null; + boolean first = true; + for (PDBChain chain : pdb.getChains()) + { + if (targetChainId.length() > 0 && !targetChainId.equals(chain.id) + && !infChain) + { + continue; // don't try to map chains don't match. + } + // TODO: correctly determine sequence type for mixed na/peptide + // structures + final String type = chain.isNa ? AlignSeq.DNA : AlignSeq.PEP; + AlignSeq as = AlignSeq.doGlobalNWAlignment(seq, chain.sequence, + type); + // equivalent to: + // AlignSeq as = new AlignSeq(sequence[s], chain.sequence, type); + // as.calcScoreMatrix(); + // as.traceAlignment(); + + if (first || as.maxscore > max + || (as.maxscore == max && chain.id.equals(targetChainId))) + { + first = false; + maxChain = chain; + max = as.maxscore; + maxAlignseq = as; + maxChainId = chain.id; + } + } + if (maxChain == null) + { + continue; + } + + if (protocol.equals(jalview.io.AppletFormatAdapter.PASTE)) + { + pdbFile = "INLINE" + pdb.getId(); + } + ArrayList seqToStrucMapping = new ArrayList(); + if (isMapUsingSIFTs) + { +<<<<<<< Updated upstream + setProgressBar(null); + setProgressBar(MessageManager + .getString("status.obtaining_mapping_with_sifts")); +======= + if (progress!=null) { + progress.setProgressBar("Obtaining mapping with SIFTS", + progressSessionId); + } +>>>>>>> Stashed changes + jalview.datamodel.Mapping sqmpping = maxAlignseq + .getMappingFromS1(false); + if (targetChainId != null && !targetChainId.trim().isEmpty()) + { + StructureMapping siftsMapping; + try + { + siftsMapping = getStructureMapping(seq, pdbFile, targetChainId, + pdb, maxChain, sqmpping, maxAlignseq); + seqToStrucMapping.add(siftsMapping); + maxChain.makeExactMapping(maxAlignseq, seq); + maxChain.transferRESNUMFeatures(seq, null); + maxChain.transferResidueAnnotation(siftsMapping, sqmpping); + } catch (SiftsException e) + { + // fall back to NW alignment + System.err.println(e.getMessage()); + StructureMapping nwMapping = getNWMappings(seq, pdbFile, + targetChainId, maxChain, pdb, maxAlignseq); + seqToStrucMapping.add(nwMapping); + } + } + else + { + ArrayList foundSiftsMappings = new ArrayList(); + for (PDBChain chain : pdb.getChains()) + { + try + { + StructureMapping siftsMapping = getStructureMapping(seq, + pdbFile, + chain.id, pdb, chain, sqmpping, maxAlignseq); + foundSiftsMappings.add(siftsMapping); + } catch (SiftsException e) + { + System.err.println(e.getMessage()); + } + } + if (!foundSiftsMappings.isEmpty()) + { + seqToStrucMapping.addAll(foundSiftsMappings); + maxChain.makeExactMapping(maxAlignseq, seq); + maxChain.transferRESNUMFeatures(seq, null); + maxChain.transferResidueAnnotation(foundSiftsMappings.get(0), + sqmpping); + } + else + { + StructureMapping nwMapping = getNWMappings(seq, pdbFile, + maxChainId, maxChain, pdb, maxAlignseq); + seqToStrucMapping.add(nwMapping); + } + } + } + else + { +<<<<<<< Updated upstream + setProgressBar(null); + setProgressBar(MessageManager + .getString("status.obtaining_mapping_with_nw_alignment")); +======= + if (progress != null) + { + progress.setProgressBar("Obtaining mapping with NW alignment", + progressSessionId); + } +>>>>>>> Stashed changes + seqToStrucMapping.add(getNWMappings(seq, pdbFile, maxChainId, + maxChain, pdb, maxAlignseq)); + } + if (forStructureView) + { + mappings.addAll(seqToStrucMapping); + } + if (progress != null) + { + progress.setProgressBar(null, progressSessionId); + } + } + return pdb; + } + + private boolean isCIFFile(String filename) + { + String fileExt = filename.substring(filename.lastIndexOf(".") + 1, + filename.length()); + return "cif".equalsIgnoreCase(fileExt); + } + + private StructureMapping getStructureMapping(SequenceI seq, + String pdbFile, String targetChainId, StructureFile pdb, + PDBChain maxChain, jalview.datamodel.Mapping sqmpping, + AlignSeq maxAlignseq) throws SiftsException + { + StructureMapping curChainMapping = siftsClient + .getSiftsStructureMapping(seq, pdbFile, targetChainId); + try + { + PDBChain chain = pdb.findChain(targetChainId); + if (chain != null) + { + chain.transferResidueAnnotation(curChainMapping, sqmpping); + } + } catch (Exception e) + { + e.printStackTrace(); + } + return curChainMapping; + } + + private StructureMapping getNWMappings(SequenceI seq, + String pdbFile, + String maxChainId, PDBChain maxChain, StructureFile pdb, + AlignSeq maxAlignseq) + { + final StringBuilder mappingDetails = new StringBuilder(128); + mappingDetails.append(NEWLINE).append( + "Sequence \u27f7 Structure mapping details"); + mappingDetails.append(NEWLINE); + mappingDetails + .append("Method: inferred with Needleman & Wunsch alignment"); + mappingDetails.append(NEWLINE).append("PDB Sequence is :") + .append(NEWLINE).append("Sequence = ") + .append(maxChain.sequence.getSequenceAsString()); + mappingDetails.append(NEWLINE).append("No of residues = ") + .append(maxChain.residues.size()).append(NEWLINE) + .append(NEWLINE); + PrintStream ps = new PrintStream(System.out) + { + @Override + public void print(String x) + { + mappingDetails.append(x); + } + + @Override + public void println() + { + mappingDetails.append(NEWLINE); + } + }; + + maxAlignseq.printAlignment(ps); + + mappingDetails.append(NEWLINE).append("PDB start/end "); + mappingDetails.append(String.valueOf(maxAlignseq.seq2start)) + .append(" "); + mappingDetails.append(String.valueOf(maxAlignseq.seq2end)); + mappingDetails.append(NEWLINE).append("SEQ start/end "); + mappingDetails.append( + String.valueOf(maxAlignseq.seq1start + (seq.getStart() - 1))) + .append(" "); + mappingDetails.append(String.valueOf(maxAlignseq.seq1end + + (seq.getStart() - 1))); + mappingDetails.append(NEWLINE); + maxChain.makeExactMapping(maxAlignseq, seq); + jalview.datamodel.Mapping sqmpping = maxAlignseq + .getMappingFromS1(false); + maxChain.transferRESNUMFeatures(seq, null); + + HashMap mapping = new HashMap(); + int resNum = -10000; + int index = 0; + char insCode = ' '; + + do + { + Atom tmp = maxChain.atoms.elementAt(index); + if ((resNum != tmp.resNumber || insCode != tmp.insCode) + && tmp.alignmentMapping != -1) + { + resNum = tmp.resNumber; + insCode = tmp.insCode; + if (tmp.alignmentMapping >= -1) + { + mapping.put(tmp.alignmentMapping + 1, new int[] { tmp.resNumber, + tmp.atomIndex }); + } + } + + index++; + } while (index < maxChain.atoms.size()); + + StructureMapping nwMapping = new StructureMapping(seq, pdbFile, + pdb.getId(), maxChainId, mapping, mappingDetails.toString()); + maxChain.transferResidueAnnotation(nwMapping, sqmpping); + return nwMapping; + } + + public void removeStructureViewerListener(Object svl, String[] pdbfiles) + { + listeners.removeElement(svl); + if (svl instanceof SequenceListener) + { + for (int i = 0; i < listeners.size(); i++) + { + if (listeners.elementAt(i) instanceof StructureListener) + { + ((StructureListener) listeners.elementAt(i)) + .releaseReferences(svl); + } + } + } + + if (pdbfiles == null) + { + return; + } + + /* + * Remove mappings to the closed listener's PDB files, but first check if + * another listener is still interested + */ + List pdbs = new ArrayList(Arrays.asList(pdbfiles)); + + StructureListener sl; + for (int i = 0; i < listeners.size(); i++) + { + if (listeners.elementAt(i) instanceof StructureListener) + { + sl = (StructureListener) listeners.elementAt(i); + for (String pdbfile : sl.getPdbFile()) + { + pdbs.remove(pdbfile); + } + } + } + + /* + * Rebuild the mappings set, retaining only those which are for 'other' PDB + * files + */ + if (pdbs.size() > 0) + { + List tmp = new ArrayList(); + for (StructureMapping sm : mappings) + { + if (!pdbs.contains(sm.pdbfile)) + { + tmp.add(sm); + } + } + + mappings = tmp; + } + } + + /** + * Propagate mouseover of a single position in a structure + * + * @param pdbResNum + * @param chain + * @param pdbfile + */ + public void mouseOverStructure(int pdbResNum, String chain, String pdbfile) + { + AtomSpec atomSpec = new AtomSpec(pdbfile, chain, pdbResNum, 0); + List atoms = Collections.singletonList(atomSpec); + mouseOverStructure(atoms); + } + + /** + * Propagate mouseover or selection of multiple positions in a structure + * + * @param atoms + */ + public void mouseOverStructure(List atoms) + { + if (listeners == null) + { + // old or prematurely sent event + return; + } + boolean hasSequenceListener = false; + for (int i = 0; i < listeners.size(); i++) + { + if (listeners.elementAt(i) instanceof SequenceListener) + { + hasSequenceListener = true; + } + } + if (!hasSequenceListener) + { + return; + } + + SearchResults results = new SearchResults(); + for (AtomSpec atom : atoms) + { + SequenceI lastseq = null; + int lastipos = -1; + for (StructureMapping sm : mappings) + { + if (sm.pdbfile.equals(atom.getPdbFile()) + && sm.pdbchain.equals(atom.getChain())) + { + int indexpos = sm.getSeqPos(atom.getPdbResNum()); + if (lastipos != indexpos && lastseq != sm.sequence) + { + results.addResult(sm.sequence, indexpos, indexpos); + lastipos = indexpos; + lastseq = sm.sequence; + // construct highlighted sequence list + for (AlignedCodonFrame acf : seqmappings) + { + acf.markMappedRegion(sm.sequence, indexpos, results); + } + } + } + } + } + for (Object li : listeners) + { + if (li instanceof SequenceListener) + { + ((SequenceListener) li).highlightSequence(results); + } + } + } + + /** + * highlight regions associated with a position (indexpos) in seq + * + * @param seq + * the sequence that the mouse over occurred on + * @param indexpos + * the absolute position being mouseovered in seq (0 to seq.length()) + * @param seqPos + * the sequence position (if -1, seq.findPosition is called to + * resolve the residue number) + */ + public void mouseOverSequence(SequenceI seq, int indexpos, int seqPos, + VamsasSource source) + { + boolean hasSequenceListeners = handlingVamsasMo + || !seqmappings.isEmpty(); + SearchResults results = null; + if (seqPos == -1) + { + seqPos = seq.findPosition(indexpos); + } + for (int i = 0; i < listeners.size(); i++) + { + Object listener = listeners.elementAt(i); + if (listener == source) + { + // TODO listener (e.g. SeqPanel) is never == source (AlignViewport) + // Temporary fudge with SequenceListener.getVamsasSource() + continue; + } + if (listener instanceof StructureListener) + { + highlightStructure((StructureListener) listener, seq, seqPos); + } + else + { + if (listener instanceof SequenceListener) + { + final SequenceListener seqListener = (SequenceListener) listener; + if (hasSequenceListeners + && seqListener.getVamsasSource() != source) + { + if (relaySeqMappings) + { + if (results == null) + { + results = MappingUtils.buildSearchResults(seq, seqPos, + seqmappings); + } + if (handlingVamsasMo) + { + results.addResult(seq, seqPos, seqPos); + + } + if (!results.isEmpty()) + { + seqListener.highlightSequence(results); + } + } + } + } + else if (listener instanceof VamsasListener && !handlingVamsasMo) + { + ((VamsasListener) listener).mouseOverSequence(seq, indexpos, + source); + } + else if (listener instanceof SecondaryStructureListener) + { + ((SecondaryStructureListener) listener).mouseOverSequence(seq, + indexpos, seqPos); + } + } + } + } + + /** + * Send suitable messages to a StructureListener to highlight atoms + * corresponding to the given sequence position(s) + * + * @param sl + * @param seq + * @param positions + */ + public void highlightStructure(StructureListener sl, SequenceI seq, + int... positions) + { + if (!sl.isListeningFor(seq)) + { + return; + } + int atomNo; + List atoms = new ArrayList(); + for (StructureMapping sm : mappings) + { + if (sm.sequence == seq + || sm.sequence == seq.getDatasetSequence() + || (sm.sequence.getDatasetSequence() != null && sm.sequence + .getDatasetSequence() == seq.getDatasetSequence())) + { + for (int index : positions) + { + atomNo = sm.getAtomNum(index); + + if (atomNo > 0) + { + atoms.add(new AtomSpec(sm.pdbfile, sm.pdbchain, sm + .getPDBResNum(index), atomNo)); + } + } + } + } + sl.highlightAtoms(atoms); + } + + /** + * true if a mouse over event from an external (ie Vamsas) source is being + * handled + */ + boolean handlingVamsasMo = false; + + long lastmsg = 0; + + /** + * as mouseOverSequence but only route event to SequenceListeners + * + * @param sequenceI + * @param position + * in an alignment sequence + */ + public void mouseOverVamsasSequence(SequenceI sequenceI, int position, + VamsasSource source) + { + handlingVamsasMo = true; + long msg = sequenceI.hashCode() * (1 + position); + if (lastmsg != msg) + { + lastmsg = msg; + mouseOverSequence(sequenceI, position, -1, source); + } + handlingVamsasMo = false; + } + + public Annotation[] colourSequenceFromStructure(SequenceI seq, + String pdbid) + { + return null; + // THIS WILL NOT BE AVAILABLE IN JALVIEW 2.3, + // UNTIL THE COLOUR BY ANNOTATION IS REWORKED + /* + * Annotation [] annotations = new Annotation[seq.getLength()]; + * + * StructureListener sl; int atomNo = 0; for (int i = 0; i < + * listeners.size(); i++) { if (listeners.elementAt(i) instanceof + * StructureListener) { sl = (StructureListener) listeners.elementAt(i); + * + * for (int j = 0; j < mappings.length; j++) { + * + * if (mappings[j].sequence == seq && mappings[j].getPdbId().equals(pdbid) + * && mappings[j].pdbfile.equals(sl.getPdbFile())) { + * System.out.println(pdbid+" "+mappings[j].getPdbId() +" + * "+mappings[j].pdbfile); + * + * java.awt.Color col; for(int index=0; index 0) { col = sl.getColour(atomNo, + * mappings[j].getPDBResNum(index), mappings[j].pdbchain, + * mappings[j].pdbfile); } + * + * annotations[index] = new Annotation("X",null,' ',0,col); } return + * annotations; } } } } + * + * return annotations; + */ + } + + public void structureSelectionChanged() + { + } + + public void sequenceSelectionChanged() + { + } + + public void sequenceColoursChanged(Object source) + { + StructureListener sl; + for (int i = 0; i < listeners.size(); i++) + { + if (listeners.elementAt(i) instanceof StructureListener) + { + sl = (StructureListener) listeners.elementAt(i); + sl.updateColours(source); + } + } + } + + public StructureMapping[] getMapping(String pdbfile) + { + List tmp = new ArrayList(); + for (StructureMapping sm : mappings) + { + if (sm.pdbfile.equals(pdbfile)) + { + tmp.add(sm); + } + } + return tmp.toArray(new StructureMapping[tmp.size()]); + } + + /** + * Returns a readable description of all mappings for the given pdbfile to any + * of the given sequences + * + * @param pdbfile + * @param seqs + * @return + */ + public String printMappings(String pdbfile, List seqs) + { + if (pdbfile == null || seqs == null || seqs.isEmpty()) + { + return ""; + } + + StringBuilder sb = new StringBuilder(64); + for (StructureMapping sm : mappings) + { + if (sm.pdbfile.equals(pdbfile) && seqs.contains(sm.sequence)) + { + sb.append(sm.mappingDetails); + sb.append(NEWLINE); + // separator makes it easier to read multiple mappings + sb.append("====================="); + sb.append(NEWLINE); + } + } + sb.append(NEWLINE); + + return sb.toString(); + } + + /** + * Remove the given mapping + * + * @param acf + */ + public void deregisterMapping(AlignedCodonFrame acf) + { + if (acf != null) + { + boolean removed = seqmappings.remove(acf); + if (removed && seqmappings.isEmpty()) + { // debug + System.out.println("All mappings removed"); + } + } + } + + /** + * Add each of the given codonFrames to the stored set, if not aready present. + * + * @param mappings + */ + public void registerMappings(List mappings) + { + if (mappings != null) + { + for (AlignedCodonFrame acf : mappings) + { + registerMapping(acf); + } + } + } + + /** + * Add the given mapping to the stored set, unless already stored. + */ + public void registerMapping(AlignedCodonFrame acf) + { + if (acf != null) + { + if (!seqmappings.contains(acf)) + { + seqmappings.add(acf); + } + } + } + + /** + * Resets this object to its initial state by removing all registered + * listeners, codon mappings, PDB file mappings + */ + public void resetAll() + { + if (mappings != null) + { + mappings.clear(); + } + if (seqmappings != null) + { + seqmappings.clear(); + } + if (sel_listeners != null) + { + sel_listeners.clear(); + } + if (listeners != null) + { + listeners.clear(); + } + if (commandListeners != null) + { + commandListeners.clear(); + } + if (view_listeners != null) + { + view_listeners.clear(); + } + if (pdbFileNameId != null) + { + pdbFileNameId.clear(); + } + if (pdbIdFileName != null) + { + pdbIdFileName.clear(); + } + } + + public void addSelectionListener(SelectionListener selecter) + { + if (!sel_listeners.contains(selecter)) + { + sel_listeners.add(selecter); + } + } + + public void removeSelectionListener(SelectionListener toremove) + { + if (sel_listeners.contains(toremove)) + { + sel_listeners.remove(toremove); + } + } + + public synchronized void sendSelection( + jalview.datamodel.SequenceGroup selection, + jalview.datamodel.ColumnSelection colsel, SelectionSource source) + { + for (SelectionListener slis : sel_listeners) + { + if (slis != source) + { + slis.selection(selection, colsel, source); + } + } + } + + Vector view_listeners = new Vector(); + + public synchronized void sendViewPosition( + jalview.api.AlignmentViewPanel source, int startRes, int endRes, + int startSeq, int endSeq) + { + + if (view_listeners != null && view_listeners.size() > 0) + { + Enumeration listeners = view_listeners + .elements(); + while (listeners.hasMoreElements()) + { + AlignmentViewPanelListener slis = listeners.nextElement(); + if (slis != source) + { + slis.viewPosition(startRes, endRes, startSeq, endSeq, source); + } + ; + } + } + } + + /** + * release all references associated with this manager provider + * + * @param jalviewLite + */ + public static void release(StructureSelectionManagerProvider jalviewLite) + { + // synchronized (instances) + { + if (instances == null) + { + return; + } + StructureSelectionManager mnger = (instances.get(jalviewLite)); + if (mnger != null) + { + instances.remove(jalviewLite); + try + { + mnger.finalize(); + } catch (Throwable x) + { + } + } + } + } + + public void registerPDBEntry(PDBEntry pdbentry) + { + if (pdbentry.getFile() != null + && pdbentry.getFile().trim().length() > 0) + { + registerPDBFile(pdbentry.getId(), pdbentry.getFile()); + } + } + + public void addCommandListener(CommandListener cl) + { + if (!commandListeners.contains(cl)) + { + commandListeners.add(cl); + } + } + + public boolean hasCommandListener(CommandListener cl) + { + return this.commandListeners.contains(cl); + } + + public boolean removeCommandListener(CommandListener l) + { + return commandListeners.remove(l); + } + + /** + * Forward a command to any command listeners (except for the command's + * source). + * + * @param command + * the command to be broadcast (in its form after being performed) + * @param undo + * if true, the command was being 'undone' + * @param source + */ + public void commandPerformed(CommandI command, boolean undo, + VamsasSource source) + { + for (CommandListener listener : commandListeners) + { + listener.mirrorCommand(command, undo, this, source); + } + } + + /** + * Returns a new CommandI representing the given command as mapped to the + * given sequences. If no mapping could be made, or the command is not of a + * mappable kind, returns null. + * + * @param command + * @param undo + * @param mapTo + * @param gapChar + * @return + */ + public CommandI mapCommand(CommandI command, boolean undo, + final AlignmentI mapTo, char gapChar) + { + if (command instanceof EditCommand) + { + return MappingUtils.mapEditCommand((EditCommand) command, undo, + mapTo, gapChar, seqmappings); + } + else if (command instanceof OrderCommand) + { + return MappingUtils.mapOrderCommand((OrderCommand) command, undo, + mapTo, seqmappings); + } + return null; + } + + public List getSequenceMappings() + { + return seqmappings; + } + +} diff --git a/src/jalview/util/SparseCount.java~ b/src/jalview/util/SparseCount.java~ new file mode 100644 index 0000000..e6b45f2 --- /dev/null +++ b/src/jalview/util/SparseCount.java~ @@ -0,0 +1,154 @@ +package jalview.util; + +import jalview.ext.android.SparseIntArray; +import jalview.ext.android.SparseShortArray; + +/** + * A class to count occurrences of characters with minimal memory footprint. + * Sparse arrays of short values are used to hold the counts, with automatic + * promotion to arrays of int if any count exceeds the maximum value for a + * short. + * + * @author gmcarstairs + * + */ +public class SparseCount +{ + private static final int DEFAULT_PROFILE_SIZE = 2; + + /* + * array of keys (chars) and values (counts) + * held either as shorts or (if shorts overflow) as ints + */ + private SparseShortArray shortProfile; + + private SparseIntArray intProfile; + + /* + * flag is set true after short overflow occurs + */ + private boolean useInts; + + /** + * Constructor which initially creates a new sparse array of short values to + * hold counts. + * + * @param profileSize + */ + public SparseCount(int profileSize) + { + this.shortProfile = new SparseShortArray(profileSize); + } + + /** + * Constructor which allocates an initial count array for only two distinct + * values (the array will grow if needed) + */ + public SparseCount() + { + this(DEFAULT_PROFILE_SIZE); + } + + /** + * Adds the given value for the given key (or sets the initial value), and + * returns the new value + * + * @param key + * @param value + */ + public int add(int key, int value) + { + int newValue = 0; + if (useInts) + { + newValue = intProfile.add(key, value); + } + else + { + try { + newValue = shortProfile.add(key, value); + } catch (ArithmeticException e) { + handleOverflow(); + newValue = intProfile.add(key, value); + } + } + return newValue; + } + + /** + * Switch from counting shorts to counting ints + */ + synchronized void handleOverflow() + { + int size = shortProfile.size(); + intProfile = new SparseIntArray(size); + for (int i = 0; i < size; i++) + { + short key = shortProfile.keyAt(i); + short value = shortProfile.valueAt(i); + intProfile.put(key, value); + } + shortProfile = null; + useInts = true; + } + + /** + * Returns the size of the profile (number of distinct items counted) + * + * @return + */ + public int size() + { + return useInts ? intProfile.size() : shortProfile.size(); + } + + /** + * Returns the value for the key (zero if no such key) + * + * @param key + * @return + */ + public int get(int key) + { + return useInts ? intProfile.get(key) : shortProfile.get(key); + } + + /** + * Sets the value for the given key + * + * @param key + * @param value + */ + public void put(int key, int value) + { + if (useInts) + { + intProfile.put(key, value); + } + else + { + shortProfile.put(key, value); + } + } + + public int keyAt(int k) + { + return useInts ? intProfile.keyAt(k) : shortProfile.keyAt(k); + } + + public int valueAt(int k) + { + return useInts ? intProfile.valueAt(k) : shortProfile.valueAt(k); + } + + /** + * Answers true if this object wraps arrays of int values, false if using + * short values + * + * @return + */ + boolean isUsingInt() + { + return useInts; + } +} diff --git a/src/jalview/viewmodel/AlignmentViewport.java b/src/jalview/viewmodel/AlignmentViewport.java index 08af2ec..7849c2d 100644 --- a/src/jalview/viewmodel/AlignmentViewport.java +++ b/src/jalview/viewmodel/AlignmentViewport.java @@ -37,6 +37,7 @@ import jalview.datamodel.AlignmentI; import jalview.datamodel.AlignmentView; import jalview.datamodel.Annotation; import jalview.datamodel.ColumnSelection; +import jalview.datamodel.ContactListI; import jalview.datamodel.HiddenColumns; import jalview.datamodel.HiddenSequences; import jalview.datamodel.ProfilesI; @@ -2931,6 +2932,12 @@ public abstract class AlignmentViewport return searchResults; } + @Override + public ContactListI getContactList(AlignmentAnnotation _aa, int column) + { + return alignment.getContactListFor(_aa, column); + } + /** * get the consensus sequence as displayed under the PID consensus annotation * row. diff --git a/src/jalview/ws/SequenceFetcher.java b/src/jalview/ws/SequenceFetcher.java index 48aafca..518e7c6 100644 --- a/src/jalview/ws/SequenceFetcher.java +++ b/src/jalview/ws/SequenceFetcher.java @@ -21,6 +21,7 @@ package jalview.ws; import jalview.ext.ensembl.EnsemblGene; +import jalview.ws.dbsources.EBIAlfaFold; import jalview.ws.dbsources.EmblCdsSource; import jalview.ws.dbsources.EmblSource; import jalview.ws.dbsources.Pdb; @@ -61,6 +62,7 @@ public class SequenceFetcher extends ASequenceFetcher addDBRefSourceImpl(PfamFull.class); addDBRefSourceImpl(PfamSeed.class); addDBRefSourceImpl(RfamSeed.class); + addDBRefSourceImpl(EBIAlfaFold.class); } /** diff --git a/src/jalview/ws/datamodel/alphafold/PAEContactMatrix.java b/src/jalview/ws/datamodel/alphafold/PAEContactMatrix.java new file mode 100644 index 0000000..e61af44 --- /dev/null +++ b/src/jalview/ws/datamodel/alphafold/PAEContactMatrix.java @@ -0,0 +1,107 @@ +package jalview.ws.datamodel.alphafold; + +import java.util.Iterator; +import java.util.List; +import java.util.Map; + +import jalview.datamodel.ContactListI; +import jalview.datamodel.ContactListImpl; +import jalview.datamodel.ContactListProviderI; +import jalview.datamodel.ContactMatrixI; +import jalview.datamodel.ContactRange; +import jalview.datamodel.SequenceI; + +public class PAEContactMatrix implements ContactMatrixI +{ + + SequenceI refSeq=null; + int maxrow=0,maxcol=0; + int[] indices1,indices2; + float[][] elements; + float maxscore; + + @SuppressWarnings("unchecked") + public PAEContactMatrix(SequenceI _refSeq, Map pae_obj) throws Exception + { + refSeq = _refSeq; + while (refSeq.getDatasetSequence()!=null) + { + refSeq=refSeq.getDatasetSequence(); + } + // convert the lists to primitive arrays and store + int length = _refSeq.getEnd()-_refSeq.getStart()+1; + + // assume indices are with respect to range defined by _refSeq on the dataset refSeq + Iterator rows = ((List)pae_obj.get("residue1")).iterator(); + Iterator cols = ((List)pae_obj.get("residue2")).iterator(); + Iterator scores = ((List)pae_obj.get("distance")).iterator(); + + elements=new float[length][length]; + while (scores.hasNext()) { + float escore=scores.next().floatValue(); + int row=rows.next().intValue(); + int col=cols.next().intValue(); + if (maxrow=elements[_column].length) + { + return -1; + } + // TODO Auto-generated method stub + return elements[_column][column]; + } + }); + } + + @Override + public float getMin() + { + return 0; + } + + @Override + public float getMax() + { + return maxscore; + } + + @Override + public boolean hasReferenceSeq() + { + return (refSeq!=null); + } + + @Override + public SequenceI getReferenceSeq() + { + return refSeq; + } + +} diff --git a/src/jalview/ws/dbsources/EBIAlfaFold.java b/src/jalview/ws/dbsources/EBIAlfaFold.java index e3687bd..7c72f4b 100644 --- a/src/jalview/ws/dbsources/EBIAlfaFold.java +++ b/src/jalview/ws/dbsources/EBIAlfaFold.java @@ -22,8 +22,12 @@ package jalview.ws.dbsources; import jalview.api.FeatureSettingsModelI; +import jalview.bin.Cache; +import jalview.bin.Console; import jalview.datamodel.AlignmentAnnotation; import jalview.datamodel.AlignmentI; +import jalview.datamodel.ContactMatrix; +import jalview.datamodel.ContactMatrixI; import jalview.datamodel.DBRefEntry; import jalview.datamodel.DBRefSource; import jalview.datamodel.PDBEntry; @@ -36,15 +40,23 @@ import jalview.io.FileFormat; import jalview.io.FileFormatI; import jalview.io.FormatAdapter; import jalview.io.PDBFeatureSettings; +import jalview.javascript.json.JSON; import jalview.structure.StructureImportSettings; import jalview.util.HttpUtils; import jalview.util.MessageManager; +import jalview.util.Platform; +import jalview.ws.datamodel.alphafold.PAEContactMatrix; import jalview.ws.ebi.EBIFetchClient; import jalview.ws.utils.UrlDownloadClient; +import java.io.BufferedReader; import java.io.File; +import java.io.FileInputStream; import java.util.ArrayList; import java.util.List; +import java.util.Map; + +import org.jmol.adapter.readers.simple.JSONReader; import com.stevesoft.pat.Regex; @@ -116,6 +128,12 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy return "https://alphafold.ebi.ac.uk/files/" + id + "-model_v1.cif"; } + public static String getAlphaFoldPaeDownloadUrl(String id) + { + return "https://alphafold.ebi.ac.uk/files/" + id + + "-predicted_aligned_error_v1.json"; + } + /* * (non-Javadoc) * @@ -146,7 +164,7 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy if (!isValidReference(id)) { System.err.println( - "(AFClient) Ignoring invalid pdb query: '" + id + "'"); + "(AFClient) Ignoring invalid alphafold query: '" + id + "'"); stopQuery(); return null; } @@ -159,6 +177,7 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy try { File tmpFile = File.createTempFile(id, ".cif"); + Console.debug("Retrieving structure file for "+id+" from "+alphaFoldCif); UrlDownloadClient.download(alphaFoldCif, tmpFile); // may not need this check ? @@ -178,6 +197,29 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy { id, ((chain == null) ? "' '" : chain) })); } + // import PAE as contact matrix - assume this will work if there was a + // model + File pae = File.createTempFile(id, "pae_json"); + String paeURL = getAlphaFoldPaeDownloadUrl(id); + + if (retrievalUrl!=null) { + // manufacture the PAE url from a url like ...-model-vN.cif + paeURL = retrievalUrl.replace("model","predicted_aligned_error").replace(".cif",".json"); + } + Console.debug("Downloading pae from " + paeURL + + " to " + pae.toString() + ""); + + try { + UrlDownloadClient.download(paeURL, pae); + if (!importPaeJSONAsContactMatrix(pdbAlignment, pae)) + { + Console.warn("Couln't import contact matrix from " + paeURL + + " (stored in " + pae.toString() + ")"); + } + } catch (Exception pae_ex) { + Console.debug("Couldn't download PAE",pae_ex); + } + } catch (Exception ex) // Problem parsing PDB file { stopQuery(); @@ -186,6 +228,24 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy return pdbAlignment; } + private boolean importPaeJSONAsContactMatrix(AlignmentI pdbAlignment, + File pae) throws Exception + { + FileInputStream pae_input = new FileInputStream(pae); + + List pae_obj = (List) Platform + .parseJSON(pae_input); + if (pae_obj == null) + { + return false; + } + ContactMatrixI matrix = new PAEContactMatrix( + pdbAlignment.getSequenceAt(0), (Map)pae_obj.get(0)); + + pdbAlignment.getSequenceAt(0).addAlignmentAnnotation(pdbAlignment.addContactList(matrix)); + return true; + } + /** * general purpose structure importer - designed to yield alignment useful for * transfer of annotation to associated sequences @@ -313,13 +373,13 @@ public class EBIAlfaFold extends EbiFileRetrievedProxy @Override public String getTestQuery() { - return "1QIP"; + return "AF-O15552-F1"; } @Override public String getDbName() { - return "PDB"; // getDbSource(); + return "ALPHAFOLD"; // getDbSource(); } @Override diff --git a/src/jalview/ws/dbsources/Pdb.java~ b/src/jalview/ws/dbsources/Pdb.java~ new file mode 100644 index 0000000..6c2f70a --- /dev/null +++ b/src/jalview/ws/dbsources/Pdb.java~ @@ -0,0 +1,294 @@ +/* + * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$) + * Copyright (C) $$Year-Rel$$ The Jalview Authors + * + * This file is part of Jalview. + * + * Jalview is free software: you can redistribute it and/or + * modify it under the terms of the GNU General Public License + * as published by the Free Software Foundation, either version 3 + * of the License, or (at your option) any later version. + * + * Jalview is distributed in the hope that it will be useful, but + * WITHOUT ANY WARRANTY; without even the implied warranty + * of MERCHANTABILITY or FITNESS FOR A PARTICULAR + * PURPOSE. See the GNU General Public License for more details. + * + * You should have received a copy of the GNU General Public License + * along with Jalview. If not, see . + * The Jalview Authors are detailed in the 'AUTHORS' file. + */ +package jalview.ws.dbsources; + +import jalview.api.FeatureSettingsModelI; +import jalview.datamodel.AlignmentAnnotation; +import jalview.datamodel.AlignmentI; +import jalview.datamodel.DBRefEntry; +import jalview.datamodel.DBRefSource; +import jalview.datamodel.PDBEntry; +import jalview.datamodel.SequenceI; +import jalview.io.FormatAdapter; +import jalview.io.PDBFeatureSettings; +import jalview.util.MessageManager; +import jalview.ws.ebi.EBIFetchClient; + +import java.util.ArrayList; +import java.util.List; +import java.util.Vector; + +import com.stevesoft.pat.Regex; + +/** + * @author JimP + * + */ +public class Pdb extends EbiFileRetrievedProxy +{ + public Pdb() + { + super(); + } + + public static final String FEATURE_INSERTION = "INSERTION"; + + public static final String FEATURE_RES_NUM = "RESNUM"; + + private static String currentDefaultFormat = DBRefSource.PDB; + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#getAccessionSeparator() + */ + @Override + public String getAccessionSeparator() + { + // TODO Auto-generated method stub + return null; + } + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#getAccessionValidator() + */ + @Override + public Regex getAccessionValidator() + { + return new Regex("([1-9][0-9A-Za-z]{3}):?([ _A-Za-z0-9]?)"); + } + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#getDbSource() + */ + @Override + public String getDbSource() + { + return DBRefSource.PDB; + } + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#getDbVersion() + */ + @Override + public String getDbVersion() + { + return "0"; + } + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#getSequenceRecords(java.lang.String[]) + */ + @Override + public AlignmentI getSequenceRecords(String queries) throws Exception + { + AlignmentI pdbAlignment = null; + Vector result = new Vector(); + String chain = null; + String id = null; + if (queries.indexOf(":") > -1) + { + chain = queries.substring(queries.indexOf(":") + 1); + id = queries.substring(0, queries.indexOf(":")); + } + else + { + id = queries; + } + if (queries.length() > 4 && chain == null) + { + chain = queries.substring(4, 5); + id = queries.substring(0, 4); + } + if (!isValidReference(id)) + { + System.err.println("Ignoring invalid pdb query: '" + id + "'"); + stopQuery(); + return null; + } + String ext = getCurrentDefaultFormat().equalsIgnoreCase("mmcif") ? ".cif" + : ".xml"; + EBIFetchClient ebi = new EBIFetchClient(); + file = ebi.fetchDataAsFile("pdb:" + id, +<<<<<<< HEAD + getCurrentDefaultFomart().toLowerCase(), ext) +======= + getCurrentDefaultFormat().toLowerCase(), "raw", ext) +>>>>>>> develop + .getAbsolutePath(); + stopQuery(); + if (file == null) + { + return null; + } + try + { + + pdbAlignment = new FormatAdapter().readFile(file, + jalview.io.AppletFormatAdapter.FILE, + getCurrentDefaultFormat()); + if (pdbAlignment != null) + { + List toremove = new ArrayList(); + for (SequenceI pdbcs : pdbAlignment.getSequences()) + { + String chid = null; + // Mapping map=null; + for (PDBEntry pid : pdbcs.getAllPDBEntries()) + { + if (pid.getFile() == file) + { + chid = pid.getChainCode(); + + } + ; + + } + if (chain == null + || (chid != null && (chid.equals(chain) + || chid.trim().equals(chain.trim()) || (chain + .trim().length() == 0 && chid.equals("_"))))) + { + pdbcs.setName(jalview.datamodel.DBRefSource.PDB + "|" + id + + "|" + pdbcs.getName()); + // Might need to add more metadata to the PDBEntry object + // like below + /* + * PDBEntry entry = new PDBEntry(); // Construct the PDBEntry + * entry.setId(id); if (entry.getProperty() == null) + * entry.setProperty(new Hashtable()); + * entry.getProperty().put("chains", pdbchain.id + "=" + + * sq.getStart() + "-" + sq.getEnd()); + * sq.getDatasetSequence().addPDBId(entry); + */ + // Add PDB DB Refs + // We make a DBRefEtntry because we have obtained the PDB file from + // a + // verifiable source + // JBPNote - PDB DBRefEntry should also carry the chain and mapping + // information + DBRefEntry dbentry = new DBRefEntry(getDbSource(), + getDbVersion(), (chid == null ? id : id + chid)); + // dbentry.setMap() + pdbcs.addDBRef(dbentry); + } + else + { + // mark this sequence to be removed from the alignment + // - since it's not from the right chain + toremove.add(pdbcs); + } + } + // now remove marked sequences + for (SequenceI pdbcs : toremove) + { + pdbAlignment.deleteSequence(pdbcs); + if (pdbcs.getAnnotation() != null) + { + for (AlignmentAnnotation aa : pdbcs.getAnnotation()) + { + pdbAlignment.deleteAnnotation(aa); + } + } + } + } + + if (pdbAlignment == null || pdbAlignment.getHeight() < 1) + { + throw new Exception(MessageManager.formatMessage( + "exception.no_pdb_records_for_chain", new String[] { id, + ((chain == null) ? "' '" : chain) })); + } + + } catch (Exception ex) // Problem parsing PDB file + { + stopQuery(); + throw (ex); + } + return pdbAlignment; + } + + /* + * (non-Javadoc) + * + * @see jalview.ws.DbSourceProxy#isValidReference(java.lang.String) + */ + @Override + public boolean isValidReference(String accession) + { + Regex r = getAccessionValidator(); + return r.search(accession.trim()); + } + + /** + * obtain human glyoxalase chain A sequence + */ + @Override + public String getTestQuery() + { + return "1QIPA"; + } + + @Override + public String getDbName() + { + return "PDB"; // getDbSource(); + } + + @Override + public int getTier() + { + return 0; + } + + public static String getCurrentDefaultFormat() + { + return currentDefaultFormat; + } + + public static void setCurrentDefaultFormat(String currentDefaultFomart) + { + Pdb.currentDefaultFormat = currentDefaultFomart; + } + + /** + * Returns a descriptor for suitable feature display settings with + *
    + *
  • ResNums or insertions features visible
    • + *
  • insertions features coloured red
    • + *
  • ResNum features coloured by label
    • + *
  • Insertions displayed above (on top of) ResNums
    • + *
+ */ + @Override + public FeatureSettingsModelI getFeatureColourScheme() + { + return new PDBFeatureSettings(); + } +} diff --git a/test/jalview/datamodel/ContactMatrixTest.java b/test/jalview/datamodel/ContactMatrixTest.java new file mode 100644 index 0000000..f0861e9 --- /dev/null +++ b/test/jalview/datamodel/ContactMatrixTest.java @@ -0,0 +1,120 @@ +package jalview.datamodel; + +import jalview.gui.JvOptionPane; + +import org.testng.Assert; +import org.testng.annotations.BeforeClass; +import org.testng.annotations.Test; + +public class ContactMatrixTest +{ + @BeforeClass(alwaysRun = true) + public void setUpJvOptionPane() + { + JvOptionPane.setInteractiveMode(false); + JvOptionPane.setMockResponse(JvOptionPane.CANCEL_OPTION); + } + + /** + * standard asserts for ContactMatrixI + */ + public static void testContactMatrixI(ContactMatrixI cm, boolean symmetric) + { + // assume contact matrix is square for text + ContactListI clist = cm.getContactList(1); + + int width = clist.getContactHeight(); + Double minValue, maxValue; + minValue = clist.getContactAt(0); + maxValue = minValue; + + for (int p = 0; p < width; p++) + { + ContactListI pList = cm.getContactList(p); + for (int q = p; q < width; q++) + { + if (q == p) + { + // compute minMax for pList + minMax(minValue, maxValue, pList); + + } + ContactListI qList = cm.getContactList(q); + if (symmetric) + { + Assert.assertEquals(qList.getContactAt(p), pList.getContactAt(q), + "Contact matrix not symmetric"); + } + else + { + Assert.assertNotEquals(qList.getContactAt(p), + pList.getContactAt(q), + "Contact matrix expected to be not symmetric"); + } + } + } + } + + private static void minMax(Double minValue, Double maxValue, + ContactListI pList) + { + int width = pList.getContactHeight(); + for (int rowcol = 0; rowcol < width; rowcol++) + { + double v = pList.getContactAt(rowcol); + if (minValue > v) + { + minValue = v; + } + if (maxValue < v) + { + maxValue = v; + } + } + } + + @Test(groups = { "Functional" }) + public void testminMaxCalc() + { + ContactListI clist = new ContactListImpl(new ContactListProviderI() + { + double[] val = { 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7 }; + + @Override + public int getContactHeight() + { + return val.length; + } + + @Override + public double getContactAt(int column) + { + if (column < 0 || column >= val.length) + { + return Double.NaN; + } + return val[column]; + } + + }); + } + + /** + * test construction and accessors for asymmetric contact matrix + */ + @Test(groups = { "Functional" }) + public void testAsymmetricContactMatrix() + { + + } + + /** + * test construction and accessors for symmetric contact matrix + */ + @Test(groups = { "Functional" }) + public void testSymmetricContactMatrix() + { + + } + +} diff --git a/test/jalview/datamodel/ContactRangeTest.java b/test/jalview/datamodel/ContactRangeTest.java new file mode 100644 index 0000000..431834c --- /dev/null +++ b/test/jalview/datamodel/ContactRangeTest.java @@ -0,0 +1,35 @@ +package jalview.datamodel; + +import org.testng.Assert; +import org.testng.annotations.Test; + +public class ContactRangeTest { + + @Test + public void testContactRangeBean() + { + ContactRange cr = new ContactRange(); + cr.update(5, 15, 6, 0.2, 12, 1.5,3.7); + Assert.assertEquals(5, cr.getFrom_column()); + Assert.assertEquals(15, cr.getTo_column()); + Assert.assertEquals(6, cr.getMinPos()); + Assert.assertEquals(0.2, cr.getMin()); + Assert.assertEquals(12, cr.getMaxPos()); + Assert.assertEquals(1.5, cr.getMax()); + Assert.assertEquals(3.7, cr.getMean()); + cr.setFrom_column(6); + Assert.assertEquals(6, cr.getFrom_column()); + cr.setTo_column(16); + Assert.assertEquals(16, cr.getTo_column()); + cr.setMinPos(7); + Assert.assertEquals(7, cr.getMinPos()); + cr.setMin(0.4); + Assert.assertEquals(0.4, cr.getMin()); + cr.setMaxPos(13); + Assert.assertEquals(13, cr.getMaxPos()); + cr.setMax(2.5); + Assert.assertEquals(2.5, cr.getMax()); + cr.setMean(3.7); + Assert.assertEquals(3.7, cr.getMean()); + } +} diff --git a/test/jalview/gui/SeqPanelTest.java b/test/jalview/gui/SeqPanelTest.java index 8cec90c..f905ef2 100644 --- a/test/jalview/gui/SeqPanelTest.java +++ b/test/jalview/gui/SeqPanelTest.java @@ -919,8 +919,8 @@ public class SeqPanelTest dna += dna; } assertEquals(dna.length(), 51200); - AlignFrame alignFrame = new FileLoader().LoadFileWaitTillLoaded(dna, - DataSourceType.PASTE); + AlignFrame alignFrame = new FileLoader() + .LoadFileWaitTillLoaded("dna "+dna, DataSourceType.PASTE); SeqPanel testee = alignFrame.alignPanel.getSeqPanel(); AlignViewport av = alignFrame.getViewport(); av.setScaleAboveWrapped(true); diff --git a/test/jalview/ws/seqfetcher/DbRefFetcherTest.java b/test/jalview/ws/seqfetcher/DbRefFetcherTest.java index 8b223d1..6769d39 100644 --- a/test/jalview/ws/seqfetcher/DbRefFetcherTest.java +++ b/test/jalview/ws/seqfetcher/DbRefFetcherTest.java @@ -20,12 +20,14 @@ */ package jalview.ws.seqfetcher; +import static org.testng.Assert.assertNotEquals; import static org.testng.AssertJUnit.assertEquals; import static org.testng.AssertJUnit.assertFalse; import static org.testng.AssertJUnit.assertNotNull; import static org.testng.AssertJUnit.assertTrue; import jalview.analysis.CrossRef; +import jalview.datamodel.AlignmentAnnotation; import jalview.datamodel.AlignmentI; import jalview.datamodel.DBRefEntry; import jalview.datamodel.DBRefSource; @@ -37,6 +39,7 @@ import jalview.gui.JvOptionPane; import jalview.util.DBRefUtils; import jalview.ws.DBRefFetcher; import jalview.ws.SequenceFetcher; +import jalview.ws.dbsources.EBIAlfaFold; import jalview.ws.dbsources.Pdb; import jalview.ws.dbsources.Uniprot; @@ -44,6 +47,7 @@ import java.util.ArrayList; import java.util.Arrays; import java.util.List; +import org.junit.Assert; import org.testng.annotations.AfterClass; import org.testng.annotations.BeforeClass; import org.testng.annotations.Test; @@ -225,4 +229,29 @@ public class DbRefFetcherTest assertEquals(dr.get(0).getSource() + "|" + dr.get(0).getAccessionId(), proteinSeq.getName()); } + + /** + * Tests retrieval of one entry from EMBLCDS. Test is dependent on + * availability of network and the EMBLCDS service. + * + * @throws Exception + */ + @Test(groups = { "External" }) + public void testAlphaFoldClien() throws Exception + { + DbSourceProxy alphafold = new EBIAlfaFold(); + AlignmentI resp = alphafold.getSequenceRecords(alphafold.getTestQuery()); + assertNotNull(resp); + assertEquals("One sequence only",resp.getHeight(), 1); + for (AlignmentAnnotation aa:resp.getAlignmentAnnotation()) { + if (aa.graph == AlignmentAnnotation.CUSTOMRENDERER) + { + assertTrue("Contact map didn't provide valid contact",resp.getContactListFor(aa, 1).getContactAt(1)!=-1d); + // test passes + return; + } + } + Assert.fail(); + } + }