test/jalview/io/CrossRef2xmlTests.java

   1 /*
   2  * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
   3  * Copyright (C) $$Year-Rel$$ The Jalview Authors
   4  *
   5  * This file is part of Jalview.
   6  *
   7  * Jalview is free software: you can redistribute it and/or
   8  * modify it under the terms of the GNU General Public License
   9  * as published by the Free Software Foundation, either version 3
  10  * of the License, or (at your option) any later version.
  11  *
  12  * Jalview is distributed in the hope that it will be useful, but
  13  * WITHOUT ANY WARRANTY; without even the implied warranty
  14  * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
  15  * PURPOSE.  See the GNU General Public License for more details.
  16  *
  17  * You should have received a copy of the GNU General Public License
  18  * along with Jalview.  If not, see <http://www.gnu.org/licenses/>.
  19  * The Jalview Authors are detailed in the 'AUTHORS' file.
  20  */
  21 package jalview.io;
  22
  23 import jalview.analysis.CrossRef;
  24 import jalview.api.AlignmentViewPanel;
  25 import jalview.datamodel.AlignedCodonFrame;
  26 import jalview.datamodel.AlignmentI;
  27 import jalview.datamodel.AlignmentTest;
  28 import jalview.datamodel.SequenceI;
  29 import jalview.gui.AlignFrame;
  30 import jalview.gui.CrossRefAction;
  31 import jalview.gui.Desktop;
  32 import jalview.gui.Jalview2XML;
  33 import jalview.gui.JvOptionPane;
  34
  35 import java.io.File;
  36 import java.io.IOException;
  37 import java.util.ArrayList;
  38 import java.util.HashMap;
  39 import java.util.List;
  40
  41 import org.testng.Assert;
  42 import org.testng.annotations.BeforeClass;
  43 import org.testng.annotations.Test;
  44
  45 @Test(singleThreaded = true)
  46 public class CrossRef2xmlTests extends Jalview2xmlBase
  47 {
  48
  49   @Override
  50   @BeforeClass(alwaysRun = true)
  51   public void setUpJvOptionPane()
  52   {
  53     JvOptionPane.setInteractiveMode(false);
  54     JvOptionPane.setMockResponse(JvOptionPane.CANCEL_OPTION);
  55   }
  56
  57   /**
  58    * test store and recovery of all reachable cross refs from all reachable
  59    * crossrefs for one or more fetched db refs. Currently, this test has a known
  60    * failure case.
  61    *
  62    * @throws Exception
  63    */
  64   @Test(groups = { "Operational" }, enabled = true)
  65   public void testRetrieveAndShowCrossref() throws Exception
  66   {
  67
  68     List<String> failedDBRetr = new ArrayList<String>();
  69     List<String> failedXrefMenuItems = new ArrayList<String>();
  70     List<String> failedProjectRecoveries = new ArrayList<String>();
  71
  72     // for every set of db queries
  73     // retrieve db query
  74     // verify presence of expected xrefs
  75     // show xrefs - verify expected type of frame is shown for each xref
  76     // show xrefs again
  77     // - verify original -> xref -> xref(original) recovers frame containing at
  78     // least the first retrieved sequence
  79     // store
  80     // 1. whole project
  81     // 2. individual frames
  82     // 3. load each one back and verify
  83     // . aligned sequences (.toString() )
  84     // . xrefs (.toString() )
  85     // . codonframes
  86     //
  87     //
  88     HashMap<String, String> dbtoviewBit = new HashMap<String, String>();
  89     List<String> keyseq = new ArrayList<String>();
  90     HashMap<String, File> savedProjects = new HashMap<String, File>();
  91
  92     for (String[] did : new String[][] { { "ENSEMBL", "ENSG00000157764" },
  93     { "UNIPROT", "P01731" } })
  94     {
  95       // pass counters - 0 - first pass, 1 means retrieve project rather than
  96       // perform action
  97       int pass1 = 0, pass2 = 0, pass3 = 0;
  98       // each do loop performs two iterations in the first outer loop pass, but
  99       // only performs one iteration on the second outer loop
 100       // ie. pass 1 = 0 {pass 2= 0 { pass 3 = 0,1 }, pass 2=1 { pass 3 = 0 }}, 1
 101       // { pass 2 = 0 { pass 3 = 0 } }
 102       do
 103       {
 104         String first = did[0] + " " + did[1];
 105         AlignFrame af = null;
 106         boolean dna;
 107         AlignmentI retral;
 108         AlignmentI dataset;
 109         SequenceI[] seqs;
 110         List<String> ptypes = null;
 111         if (pass1 == 0)
 112         {
 113           // retrieve dbref
 114
 115           List<AlignFrame> afs = jalview.gui.SequenceFetcher.fetchAndShow(
 116                   did[0], did[1]);
 117           if (afs.size() == 0)
 118           {
 119             failedDBRetr.add("Didn't retrieve " + first);
 120             break;
 121           }
 122           keyseq.add(first);
 123           af = afs.get(0);
 124
 125           // verify references for retrieved data
 126           AlignmentTest.assertAlignmentDatasetRefs(af.getViewport()
 127                   .getAlignment(), "Pass (" + pass1 + "," + pass2 + ","
 128                   + pass3 + "): Fetch " + first + ":");
 129           assertDatasetIsNormalisedKnownDefect(af.getViewport()
 130                   .getAlignment(), "Pass (" + pass1 + "," + pass2 + ","
 131                   + pass3 + "): Fetch " + first + ":");
 132           dna = af.getViewport().getAlignment().isNucleotide();
 133           retral = af.getViewport().getAlignment();
 134           dataset = retral.getDataset();
 135           seqs = retral.getSequencesArray();
 136
 137         }
 138         else
 139         {
 140           Desktop.instance.closeAll_actionPerformed(null);
 141           // recover stored project
 142           af = new FileLoader(false).LoadFileWaitTillLoaded(savedProjects
 143                   .get(first).toString(), FormatAdapter.FILE);
 144           System.out.println("Recovered view for '" + first + "' from '"
 145                   + savedProjects.get(first).toString() + "'");
 146           dna = af.getViewport().getAlignment().isNucleotide();
 147           retral = af.getViewport().getAlignment();
 148           dataset = retral.getDataset();
 149           seqs = retral.getSequencesArray();
 150
 151           // verify references for recovered data
 152           AlignmentTest.assertAlignmentDatasetRefs(af.getViewport()
 153                   .getAlignment(), "Pass (" + pass1 + "," + pass2 + ","
 154                   + pass3 + "): Recover " + first + ":");
 155           assertDatasetIsNormalisedKnownDefect(af.getViewport()
 156                   .getAlignment(), "Pass (" + pass1 + "," + pass2 + ","
 157                   + pass3 + "): Recover " + first + ":");
 158
 159         }
 160
 161         // store project on first pass, compare next pass
 162         stringify(dbtoviewBit, savedProjects, first, af.alignPanel);
 163
 164         ptypes = (seqs == null || seqs.length == 0) ? null : new CrossRef(
 165                 seqs, dataset).findXrefSourcesForSequences(dna);
 166
 167         // start of pass2: retrieve each cross-ref for fetched or restored
 168         // project.
 169         do // first cross ref and recover crossref loop
 170         {
 171
 172           for (String db : ptypes)
 173           {
 174             // counter for splitframe views retrieved via crossref
 175             int firstcr_ap = 0;
 176             // build next key so we an retrieve all views
 177             String nextxref = first + " -> " + db + "{" + firstcr_ap + "}";
 178             // perform crossref action, or retrieve stored project
 179             List<AlignmentViewPanel> cra_views = new ArrayList<AlignmentViewPanel>();
 180             CrossRefAction cra = null;
 181
 182             if (pass2 == 0)
 183             { // retrieve and show cross-refs in this thread
 184               cra = new CrossRefAction(af, seqs, dna, db);
 185               cra.run();
 186               if (cra.getXrefViews().size() == 0)
 187               {
 188                 failedXrefMenuItems.add("No crossrefs retrieved for "
 189                         + first + " -> " + db);
 190                 continue;
 191               }
 192               cra_views = cra.getXrefViews();
 193               assertNucleotide(cra_views.get(0),
 194                       "Nucleotide panel included proteins for " + first
 195                               + " -> " + db);
 196               assertProtein(cra_views.get(1),
 197                       "Protein panel included nucleotides for " + first
 198                               + " -> " + db);
 199             }
 200             else
 201             {
 202               Desktop.instance.closeAll_actionPerformed(null);
 203               pass3 = 0;
 204               // recover stored project
 205               File storedProject = savedProjects.get(nextxref);
 206               if (storedProject == null)
 207               {
 208                 failedProjectRecoveries.add("Failed to store a view for '"
 209                         + nextxref + "'");
 210                 continue;
 211               }
 212
 213               // recover stored project
 214               AlignFrame af2 = new FileLoader(false)
 215                       .LoadFileWaitTillLoaded(savedProjects.get(nextxref)
 216                               .toString(), FormatAdapter.FILE);
 217               System.out.println("Recovered view for '" + nextxref
 218                       + "' from '" + savedProjects.get(nextxref).toString()
 219                       + "'");
 220               // gymnastics to recover the alignPanel/Complementary alignPanel
 221               if (af2.getViewport().isNucleotide())
 222               {
 223                 // top view, then bottom
 224                 cra_views.add(af2.getViewport().getAlignPanel());
 225                 cra_views.add(((jalview.gui.AlignViewport) af2
 226                         .getViewport().getCodingComplement())
 227                         .getAlignPanel());
 228
 229               }
 230               else
 231               {
 232                 // bottom view, then top
 233                 cra_views.add(((jalview.gui.AlignViewport) af2
 234                         .getViewport().getCodingComplement())
 235                         .getAlignPanel());
 236                 cra_views.add(af2.getViewport().getAlignPanel());
 237
 238               }
 239             }
 240             HashMap<String, List<String>> xrptypes = new HashMap<String, List<String>>();
 241             // first save/verify views.
 242             for (AlignmentViewPanel avp : cra_views)
 243             {
 244               nextxref = first + " -> " + db + "{" + firstcr_ap++ + "}";
 245               // verify references for this panel
 246               AlignmentTest.assertAlignmentDatasetRefs(avp.getAlignment(),
 247                       "Pass (" + pass1 + "," + pass2 + "," + pass3
 248                               + "): before start of pass3: " + nextxref
 249                               + ":");
 250               assertDatasetIsNormalisedKnownDefect(avp.getAlignment(),
 251                       "Pass (" + pass1 + "," + pass2 + "," + pass3
 252                               + "): before start of pass3: " + nextxref
 253                               + ":");
 254
 255               SequenceI[] xrseqs = avp.getAlignment().getSequencesArray();
 256
 257               List<String> _xrptypes = (seqs == null || seqs.length == 0) ? null
 258                       : new CrossRef(xrseqs, dataset)
 259                               .findXrefSourcesForSequences(avp
 260                                       .getAlignViewport().isNucleotide());
 261
 262               stringify(dbtoviewBit, savedProjects, nextxref, avp);
 263               xrptypes.put(nextxref, _xrptypes);
 264
 265             }
 266
 267             // now do the second xref pass starting from either saved or just
 268             // recovered split pane, in sequence
 269             do // retrieve second set of cross refs or recover and verify
 270             {
 271               firstcr_ap = 0;
 272               for (AlignmentViewPanel avp : cra_views)
 273               {
 274                 nextxref = first + " -> " + db + "{" + firstcr_ap++ + "}";
 275                 for (String xrefdb : xrptypes.get(nextxref))
 276                 {
 277                   List<AlignmentViewPanel> cra_views2 = new ArrayList<AlignmentViewPanel>();
 278                   int q = 0;
 279                   String nextnextxref = nextxref + " -> " + xrefdb + "{"
 280                           + q + "}";
 281
 282                   if (pass3 == 0)
 283                   {
 284
 285                     SequenceI[] xrseqs = avp.getAlignment()
 286                             .getSequencesArray();
 287                     AlignFrame nextaf = Desktop.getAlignFrameFor(avp
 288                             .getAlignViewport());
 289
 290                     cra = new CrossRefAction(nextaf, xrseqs, avp
 291                             .getAlignViewport().isNucleotide(), xrefdb);
 292                     cra.run();
 293                     if (cra.getXrefViews().size() == 0)
 294                     {
 295                       failedXrefMenuItems
 296                               .add("No crossrefs retrieved for '"
 297                                       + nextxref + "' to " + xrefdb
 298                                       + " via '" + nextaf.getTitle() + "'");
 299                       continue;
 300                     }
 301                     cra_views2 = cra.getXrefViews();
 302                     assertNucleotide(cra_views2.get(0),
 303                             "Nucleotide panel included proteins for '"
 304                                     + nextxref + "' to " + xrefdb
 305                                     + " via '" + nextaf.getTitle() + "'");
 306                     assertProtein(cra_views2.get(1),
 307                             "Protein panel included nucleotides for '"
 308                                     + nextxref + "' to " + xrefdb
 309                                     + " via '" + nextaf.getTitle() + "'");
 310
 311                   }
 312                   else
 313                   {
 314                     Desktop.instance.closeAll_actionPerformed(null);
 315                     // recover stored project
 316                     File storedProject = savedProjects.get(nextnextxref);
 317                     if (storedProject == null)
 318                     {
 319                       failedProjectRecoveries
 320                               .add("Failed to store a view for '"
 321                                       + nextnextxref + "'");
 322                       continue;
 323                     }
 324                     AlignFrame af2 = new FileLoader(false)
 325                             .LoadFileWaitTillLoaded(
 326                                     savedProjects.get(nextnextxref)
 327                                             .toString(), FormatAdapter.FILE);
 328                     System.out.println("Recovered view for '"
 329                             + nextnextxref + "' from '"
 330                             + savedProjects.get(nextnextxref).toString()
 331                             + "'");
 332                     // gymnastics to recover the alignPanel/Complementary
 333                     // alignPanel
 334                     if (af2.getViewport().isNucleotide())
 335                     {
 336                       // top view, then bottom
 337                       cra_views2.add(af2.getViewport().getAlignPanel());
 338                       cra_views2.add(((jalview.gui.AlignViewport) af2
 339                               .getViewport().getCodingComplement())
 340                               .getAlignPanel());
 341
 342                     }
 343                     else
 344                     {
 345                       // bottom view, then top
 346                       cra_views2.add(((jalview.gui.AlignViewport) af2
 347                               .getViewport().getCodingComplement())
 348                               .getAlignPanel());
 349                       cra_views2.add(af2.getViewport().getAlignPanel());
 350                     }
 351                     Assert.assertEquals(cra_views2.size(), 2);
 352                     Assert.assertNotNull(cra_views2.get(0));
 353                     Assert.assertNotNull(cra_views2.get(1));
 354                   }
 355
 356                   for (AlignmentViewPanel nextavp : cra_views2)
 357                   {
 358                     nextnextxref = nextxref + " -> " + xrefdb + "{" + q++
 359                             + "}";
 360
 361                     // verify references for this panel
 362                     AlignmentTest.assertAlignmentDatasetRefs(
 363                             nextavp.getAlignment(), "" + "Pass (" + pass1
 364                                     + "," + pass2 + "): For "
 365                                     + nextnextxref + ":");
 366                     assertDatasetIsNormalisedKnownDefect(
 367                             nextavp.getAlignment(), "" + "Pass (" + pass1
 368                                     + "," + pass2 + "): For "
 369                                     + nextnextxref + ":");
 370
 371                     stringify(dbtoviewBit, savedProjects, nextnextxref,
 372                             nextavp);
 373                     keyseq.add(nextnextxref);
 374                   }
 375                 } // end of loop around showing all xrefdb for crossrf2
 376
 377               } // end of loop around all viewpanels from crossrf1
 378             } while (pass2 == 2 && pass3++ < 2);
 379             // fetchdb->crossref1->crossref-2->verify for xrefs we
 380             // either loop twice when pass2=0, or just once when pass2=1
 381             // (recovered project from previous crossref)
 382
 383           } // end of loop over db-xrefs for crossref-2
 384
 385           // fetchdb-->crossref1
 386           // for each xref we try to retrieve xref, store and verify when
 387           // pass1=0, or just retrieve and verify when pass1=1
 388         } while (pass1 == 1 && pass2++ < 2);
 389         // fetchdb
 390         // for each ref we
 391         // loop twice: first, do the retrieve, second recover from saved project
 392
 393         // increment pass counters, so we repeat traversal starting from the
 394         // oldest saved project first.
 395         if (pass1 == 0)
 396         {
 397           // verify stored projects for first set of cross references
 398           pass1 = 1;
 399           // and verify cross-references retrieved from stored projects
 400           pass2 = 0;
 401           pass3 = 0;
 402         }
 403         else
 404         {
 405           pass1++;
 406         }
 407       } while (pass1 < 3);
 408     }
 409     if (failedXrefMenuItems.size() > 0)
 410     {
 411       for (String s : failedXrefMenuItems)
 412       {
 413         System.err.println(s);
 414       }
 415       Assert.fail("Faulty xref menu (" + failedXrefMenuItems.size()
 416               + " counts)");
 417     }
 418     if (failedProjectRecoveries.size() > 0)
 419     {
 420
 421       for (String s : failedProjectRecoveries)
 422       {
 423         System.err.println(s);
 424       }
 425       Assert.fail("Didn't recover projects for some retrievals (did they retrieve ?) ("
 426               + failedProjectRecoveries.size() + " counts)");
 427     }
 428     if (failedDBRetr.size() > 0)
 429     {
 430       for (String s : failedProjectRecoveries)
 431       {
 432         System.err.println(s);
 433       }
 434       Assert.fail("Didn't retrieve some db refs for checking cross-refs ("
 435               + failedDBRetr.size() + " counts)");
 436     }
 437   }
 438
 439   /**
 440    * wrapper to trap known defect for AH002001 testcase
 441    *
 442    * @param alignment
 443    * @param string
 444    */
 445   private void assertDatasetIsNormalisedKnownDefect(AlignmentI al,
 446           String message)
 447   {
 448     try
 449     {
 450       AlignmentTest.assertDatasetIsNormalised(al, message);
 451     } catch (AssertionError ae)
 452     {
 453       if (!ae.getMessage().endsWith("EMBL|AH002001"))
 454       {
 455         throw ae;
 456       }
 457       else
 458       {
 459         System.out
 460                 .println("Ignored exception for known defect: JAL-2179 : "
 461                         + message);
 462       }
 463
 464     }
 465   }
 466
 467   private void assertProtein(AlignmentViewPanel alignmentViewPanel,
 468           String message)
 469   {
 470     assertType(true, alignmentViewPanel, message);
 471   }
 472
 473   private void assertNucleotide(AlignmentViewPanel alignmentViewPanel,
 474           String message)
 475   {
 476     assertType(false, alignmentViewPanel, message);
 477   }
 478
 479   private void assertType(boolean expectProtein,
 480           AlignmentViewPanel alignmentViewPanel, String message)
 481   {
 482     List<SequenceI> nonType = new ArrayList<SequenceI>();
 483     for (SequenceI sq : alignmentViewPanel.getAlignViewport()
 484             .getAlignment().getSequences())
 485     {
 486       if (sq.isProtein() != expectProtein)
 487       {
 488         nonType.add(sq);
 489       }
 490     }
 491     if (nonType.size() > 0)
 492     {
 493       Assert.fail(message + " [ "
 494               + (expectProtein ? "nucleotides were " : "proteins were ")
 495               + nonType.toString() + " ]");
 496     }
 497   }
 498
 499   /**
 500    * first time called, record strings derived from alignment and
 501    * alignedcodonframes, and save view to a project file. Second time called,
 502    * compare strings to existing ones. org.testng.Assert.assertTrue on
 503    * stringmatch
 504    *
 505    * @param dbtoviewBit
 506    *          map between xrefpath and view string
 507    * @param savedProjects
 508    *          - map from xrefpath to saved project filename (createTempFile)
 509    * @param xrefpath
 510    *          - xrefpath - unique ID for this context (composed of sequence of
 511    *          db-fetch/cross-ref actions preceeding state)
 512    * @param avp
 513    *          - viewpanel to store (for viewpanels in splitframe, the same
 514    *          project should be written for both panels, only one needs
 515    *          recovering for comparison on the next stringify call, but each
 516    *          viewpanel needs to be called with a distinct xrefpath to ensure
 517    *          each one's strings are compared)
 518    */
 519   private void stringify(HashMap<String, String> dbtoviewBit,
 520           HashMap<String, File> savedProjects, String xrefpath,
 521           AlignmentViewPanel avp)
 522   {
 523     if (savedProjects != null)
 524     {
 525       if (savedProjects.get(xrefpath) == null)
 526       {
 527         // write a project file for this view. On the second pass, this will be
 528         // recovered and cross-references verified
 529         try
 530         {
 531           File prfile = File.createTempFile("crossRefTest", ".jvp");
 532           AlignFrame af = Desktop.getAlignFrameFor(avp.getAlignViewport());
 533           new Jalview2XML(false).saveAlignment(af, prfile.toString(),
 534                   af.getTitle());
 535           System.out.println("Written view from '" + xrefpath + "' as '"
 536                   + prfile.getAbsolutePath() + "'");
 537           savedProjects.put(xrefpath, prfile);
 538         } catch (IOException q)
 539         {
 540           Assert.fail("Unexpected IO Exception", q);
 541         }
 542       }
 543       else
 544       {
 545         System.out.println("Stringify check on view from '" + xrefpath
 546                 + "' [ possibly retrieved from '"
 547                 + savedProjects.get(xrefpath).getAbsolutePath() + "' ]");
 548
 549       }
 550     }
 551
 552     StringBuilder sbr = new StringBuilder();
 553     sbr.append(avp.getAlignment().toString());
 554     sbr.append("\n");
 555     sbr.append("<End of alignment>");
 556     sbr.append("\n");
 557     sbr.append(avp.getAlignment().getDataset());
 558     sbr.append("\n");
 559     sbr.append("<End of dataset>");
 560     sbr.append("\n");
 561     int p = 0;
 562     if (avp.getAlignment().getCodonFrames() != null)
 563     {
 564       for (AlignedCodonFrame ac : avp.getAlignment().getCodonFrames())
 565       {
 566         sbr.append("<AlignedCodonFrame " + p++ + ">");
 567         sbr.append("\n");
 568         sbr.append(ac.toString());
 569         sbr.append("\n");
 570       }
 571     }
 572     String dbt = dbtoviewBit.get(xrefpath);
 573     if (dbt == null)
 574     {
 575       dbtoviewBit.put(xrefpath, sbr.toString());
 576     }
 577     else
 578     {
 579       Assert.assertEquals(sbr.toString(), dbt, "stringify mismatch for "
 580               + xrefpath);
 581     }
 582   }
 583 }