1 HMMER - profile hidden Markov models for biological sequence analysis
2 Version 2.2 (August 2001)
3 Copyright (C) 1992-2001 Washington University School of Medicine
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6 o About this software...
7 HMMER is an implementation of profile HMM methods for
8 sensitive database searches using multiple sequence alignments as queries.
10 Basically, you give HMMER a multiple sequence alignment as input;
11 it builds a statistical model called a "hidden Markov model"
12 which you can then use as a query into a sequence database
13 to find (and/or align) additional homologues of the sequence family.
16 WWW home: http://hmmer.wustl.edu/
17 Distribution: ftp://ftp.genetics.wustl.edu/pub/eddy/hmmer/
20 See the file INSTALL for brief instructions.
21 See the chapter Installation in the HMMER User's Guide for more
22 detailed instructions.
24 You should also read the following files:
25 COPYING -- copyright notice, and information on the free software license
26 LICENSE -- Full text of the GNU Public License, version 2 (see COPYING)
28 If you have obtained HMMER from Washington University under
29 a non-GPL license as part of a special licensing agreement,
30 COPYING and LICENSE will refer to the terms of that agreement.
32 o Getting started with HMMER
33 The User's Guide is in Userguide/Userguide.pdf [Adobe PDF format].
34 It is also available online as hypertext:
35 http://hmmer.wustl.edu/hmmer-html/
37 A quick tutorial intro is given as the first chapter of
41 Email eddy@genetics.wustl.edu to register and get on my
42 infrequent mailing list of HMMER news, patches, and updates.
45 These programs are under active development. Though this
46 release has been tested and appears to be stable, bugs may crop up. If
47 you use these programs, please help me out and e-mail me with
48 suggestions, comments, and bug reports. (eddy@genetics.wustl.edu)
52 Howard Hughes Medical Institute and Dept. of Genetics
53 Washington University School of Medicine, St. Louis, Missouri, USA
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