3 * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
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16 * PURPOSE. See the GNU General Public License for more details.
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23 <title>Hidden Regions</title>
27 <strong>Hidden Regions</strong>
29 <p>Use the keyboard key "H" to hide / reveal selected
30 columns and sequences. To hide / reveal only selected sequences, use
31 "Shift H", to hide / reveal only selected columns, use
32 "Control H". You can also use "Shift" and
33 "Control" together to hide everything but the currently
36 <strong><em>Hiding Sequences</em></strong><br> To hide selected
37 sequences in an alignment, use the <strong>"View ->
38 Hide -> Selected Sequences"</strong> menu item or simply select <strong>"Hide
39 Sequences"</strong> from the Popup menu after a right click on the
42 <p>Hidden sequences will not be used in any calculations, editing
43 or web service alignments performed on visible sequences.</p>
45 <strong><em>Hidden Sequences Representatives</em></strong><br>
46 A more advanced hide involves a right-mouse click on a sequence,
47 then selecting <strong>"SequenceID -> Represent
48 Group with SequenceId"</strong>. Using this method of hiding
49 sequences, any edits performed on the visible group representative
50 will be propagated to all the sequences in that group. <br> The
51 hidden representative sequences will not be used in any calculations
52 or web service alignments (<em>nb. this may change in the
55 <strong><em>Hidden Sequence Representatives and
56 Multiple Views</em></strong><br> <em>A word of warning: hidden
57 representative sequence groups are (still) only partly implemented
58 in the Jalview 2.5 release, and we hope to deal with the following
59 issues in the future.</em><br> Currently, represented hidden
60 groups are only made correctly if there is just one alignment view.
61 When multiple views on an alignment exist, then the represented
62 group will be displayed correctly in the view in which it was made,
63 but in other views, both representative and hidden sequences will be
64 visible, but will behave as if they are grouped. <br> Hidden
65 representatives are propagated correctly to a new view if they exist
66 in the current view. However, if the represented sequences are
67 revealed in any one view, then in all other views they will simply
68 be marked as hidden, and their association with the representative
69 sequence will be lost.<br>
73 <strong><em>Hiding Columns</em></strong><br> To hide selected
74 columns in an alignment, use the <strong>"View ->
75 Hide -> Selected Columns"</strong> menu item, or right click within
76 a region of selected columns in the scale above the alignment (only
77 available in non wrapped mode) and select <strong>"Hide
78 Columns"</strong>.
80 <p>When an alignment view contains hidden columns, certain
83 <li>Editing the alignment is bound by the hidden columns, <em>i.e.</em>
84 you cannot move residues across a hidden column boundary.
86 <li><strong><a href="../calculations/tree.html">Tree</a></strong>,
87 <strong><a href="../calculations/pairwise.html">pairwise
88 alignment</a></strong> and <strong><a
89 href="../calculations/pca.html">PCA</a></strong> calculations will
90 only be performed using the <em>visible</em> parts of the
92 <li><a href="../webServices/msaclient.html">Multiple
93 Sequence Alignments</a> are performed locally on on each visible
94 chunk of the input, and concatenated with the hidden regions to
95 form the final result.
99 <strong>Column Separability</strong><br> Calculations where
100 hidden columns are excluded, and a single analysis performed on the
101 result, are termed <em>column-separable</em>. The simple Tree and
102 PCA calculations are column separable because essentially the same
103 results would be obtained if the excluded hidden columns were
104 replaced by gaps as the input to the calculation.
106 <p>Multiple Sequence alignment and secondary structure prediction
107 are both non-column-separable, and so the exclusion of hidden
108 regions leads to only 'locally optimal' results - sometimes
109 different to that obtained when using the full alignment.</p>