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23 <title>Alignment Consensus Annotation</title>
27 <strong>Alignment Consensus Annotation</strong>
29 <p>The consensus displayed below the alignment is the percentage
30 of the modal residue per column. By default this calculation
31 includes gaps in columns. You can choose to ignore gaps in the
32 calculation by right clicking on the label "Consensus" to
33 the left of the consensus bar chart.
34 <p>If the modal value is shared by more than 1 residue, a
35 "+" symbol is used in the display for the simple reason
36 that it is not possible to display multiple characters in a single
39 <strong>Copying the consensus sequence</strong>
42 Select the <strong>"Copy Consensus Sequence"</strong>
43 entry from the consensus annotation label to copy the alignment's
44 consensus sequence to the clipboard.
46 <a name="logo"><strong>Sequence logo</strong></a>
48 By clicking on the label you can also activate the sequence logo. It
49 indicates the relative amount of residues per column which can be
50 estimated by its size in the logo. The tooltip of a column gives the
51 exact numbers for all occurring residues.
52 <br />If columns of the alignment are very diverse, then it can
53 sometimes be difficult to see the sequence logo - in this case, right
54 click on the annotation row label and select
55 <strong>Normalise Consensus Logo</strong> to scale all columns of the
56 logo to the same height.
59 <strong>Group Consensus</strong><br> If sequence groups have
60 been defined, then selecting option 'Group Consensus' in the <a
61 href="../menus/alwannotation.html">Annotations menu</a> will
62 result in Consensus being calculated for each group, as well as the
66 <strong>cDNA Consensus</strong>
69 <a href="../features/splitView.html">Split Frame View</a> of cDNA and
70 Protein alignments will show the consensus for cDNA below the protein
72 <br /> This may provide additional information on mutations in DNA
73 that is not visible in the peptide alignment.