3 * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
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16 * PURPOSE. See the GNU General Public License for more details.
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20 * The Jalview Authors are detailed in the 'AUTHORS' file.
23 <title>What's new ?</title>
27 <strong>What's new ?</strong>
30 Jalview 2.9.0b2 is a bug fix release for Jalview 2.9.
31 The release of Jalview 2.9 in September 2015 included
32 a multitude of bug fixes and minor improvements (both small, and
33 rather big!), it also brings major new capabilities for codon-level
34 analysis of protein alignments and the retrieval and manipulation of
35 structural data.</p><p>For the patches since version 2.9 was released, see the
36 <a href="releases.html#Jalview.2.9.0b2">Jalview 2.9.0b2 Release Notes</a>.
39 <strong>Highlights in Jalview 2.9</strong>
41 <li><strong>Visualisation, editing and analysis of
42 cDNA and Protein alignments</strong><br />A new <a
43 href="features/splitView.html">Split View</a> window allows linked
44 protein and nucleotide sequence alignments to be viewed, edited,
45 and analysed as one. <br />cDNA alignments can also be
46 reconstructed from protein alignments calculated by Jalview's web
47 services, and update in response to edits in the amino acid view.<br />To
48 start experimenting with cDNA/Protein analysis, jut drop a file
49 containing cDNA sequences which code for proteins in an existing
50 alignment, and Jalview will do the rest.</li>
51 <li><strong>Enhanced Integration of UCSF Chimera</strong> <br>Jalview
52 2.9 provides full support for the use of Chimera to view 3D
53 structures linked to alignment views in the Jalview Desktop. We've
54 also included support for saving Chimera sessions in Jalview
55 project files.<br />Jalview and Chimera communicate using local
56 web server connections, which may cause firewall alerts on some
57 systems, but has the advantage of allowing bidirectional
58 communication. Communication between Jalview and Chimera is now
59 much more responsive, and selected regions in Chimera are now
60 shown as highlighted regions in the Jalview desktop.</li>
61 <li><strong>Interactive querying of the PDBe</strong><br />Jalview
62 users can now <a href="features/pdbsequencefetcher.html">browse</a> and <a href="features/viewingpdbs.html">retrieve 3D structure</a> data from the PDB
63 via the <a href="http://www.ebi.ac.uk/pdbe/api/doc/search.html">PDBe
64 Search API</a> (<a href="http://dx.doi.org/10.1093%2Fnar%2Fgkt1180">Gutmanas
65 et al 2014</a>). Developed in collaboration with the PDBe group at
66 EMBL-EBI, the interface allows both structured and free-text
67 queries to be performed, and allows automatic selection of the
68 most relevant structures for an alignment acording to a variety of
70 <li><strong>Improved support for RNA visualisation</strong><br />Jalview
71 2.9 integrates the latest version of the <a
72 href="features/varna.html">VARNA RNA Viewer</a>, and VARNA views
73 can also now be stored in Jalview projects. We've also dealt with
74 a number of lingering bugs in the VARNA/Jalview interface,
75 including the loss of pseudoknots when RNA secondary structure is
77 <li><strong>Protein Secondary Structure predictions
78 with JPred4</strong><br />Jalview includes a number of new features for
79 working with secondary structure predictions from the JPred4
80 server. These include new <a href="menus/popupMenu.html#hideinserts">popup menu actions</a> to automatically hide insertions and highlight
81 mutations in an alignment with respect to a <a href="calculations/referenceseq.html">Reference
82 Sequence</a>. Jalview 2.9's new <a href="io/export.html#htmlexport">scrollable
83 SVG HTML export</a> was also developed specifically for the JPred4