2 * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
3 * Copyright (C) $$Year-Rel$$ The Jalview Authors
5 * This file is part of Jalview.
7 * Jalview is free software: you can redistribute it and/or
8 * modify it under the terms of the GNU General Public License
9 * as published by the Free Software Foundation, either version 3
10 * of the License, or (at your option) any later version.
12 * Jalview is distributed in the hope that it will be useful, but
13 * WITHOUT ANY WARRANTY; without even the implied warranty
14 * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
15 * PURPOSE. See the GNU General Public License for more details.
17 * You should have received a copy of the GNU General Public License
18 * along with Jalview. If not, see <http://www.gnu.org/licenses/>.
19 * The Jalview Authors are detailed in the 'AUTHORS' file.
21 package jalview.ext.ensembl;
23 import jalview.datamodel.AlignmentI;
24 import jalview.datamodel.SequenceFeature;
26 import com.stevesoft.pat.Regex;
29 * A client to fetch protein translated sequence for an Ensembl identifier
34 public class EnsemblProtein extends EnsemblSeqProxy
37 * accepts ENSP with 11 digits
38 * or ENSMUSP or similar for other species
39 * or CCDSnnnnn.nn with at least 3 digits
41 private static final Regex ACCESSION_REGEX = new Regex(
42 "(ENS([A-Z]{3}|)P[0-9]{11}$)" + "|" + "(CCDS[0-9.]{3,}$)");
45 * Default constructor (to use rest.ensembl.org)
47 public EnsemblProtein()
53 * Constructor given the target domain to fetch data from
57 public EnsemblProtein(String d)
63 public String getDbName()
65 return "ENSEMBL (Protein)";
69 protected EnsemblSeqType getSourceEnsemblType()
71 return EnsemblSeqType.PROTEIN;
75 * Returns false, as this fetcher does not retrieve DNA sequences.
78 public boolean isDnaCoding()
84 * Test query is to the protein translation of transcript ENST00000288602
87 public String getTestQuery()
89 return "ENSP00000288602";
93 * Overrides base class method to do nothing - genomic features are not
94 * applicable to the protein product sequence
97 protected void addFeaturesAndProduct(String accId, AlignmentI alignment)
102 protected EnsemblFeatureType[] getFeaturesToFetch()
104 // not applicable - can't fetch genomic features for a protein sequence
109 protected boolean identifiesSequence(SequenceFeature sf, String accId)
111 // not applicable - protein sequence is not a 'subset' of genomic sequence
116 public Regex getAccessionValidator()
118 return ACCESSION_REGEX;
122 * Returns an accession id for a query, including conversion of ENST* to
123 * ENSP*. This supports querying for the protein sequence for a transcript
124 * (ENST identifier) and returning the ENSP identifier.
127 public String getAccessionIdFromQuery(String query)
129 String accId = super.getAccessionIdFromQuery(query);
132 * ensure last character before (11) digits is P
133 * ENST00000288602 -> ENSP00000288602
134 * ENSMUST00000288602 -> ENSMUSP00000288602
136 if (accId != null && accId.length() >= 12)
138 char[] chars = accId.toCharArray();
139 chars[chars.length - 12] = 'P';
140 accId = new String(chars);