2 * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
3 * Copyright (C) $$Year-Rel$$ The Jalview Authors
5 * This file is part of Jalview.
7 * Jalview is free software: you can redistribute it and/or
8 * modify it under the terms of the GNU General Public License
9 * as published by the Free Software Foundation, either version 3
10 * of the License, or (at your option) any later version.
12 * Jalview is distributed in the hope that it will be useful, but
13 * WITHOUT ANY WARRANTY; without even the implied warranty
14 * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
15 * PURPOSE. See the GNU General Public License for more details.
17 * You should have received a copy of the GNU General Public License
18 * along with Jalview. If not, see <http://www.gnu.org/licenses/>.
19 * The Jalview Authors are detailed in the 'AUTHORS' file.
23 import jalview.api.FeatureSettingsModelI;
24 import jalview.bin.Cache;
25 import jalview.datamodel.AlignmentI;
26 import jalview.datamodel.DBRefEntry;
27 import jalview.datamodel.SequenceFeature;
28 import jalview.datamodel.SequenceI;
29 import jalview.fts.service.pdb.PDBFTSPanel;
30 import jalview.fts.service.uniprot.UniprotFTSPanel;
31 import jalview.io.gff.SequenceOntologyI;
32 import jalview.util.DBRefUtils;
33 import jalview.util.MessageManager;
34 import jalview.util.Platform;
35 import jalview.ws.dbsources.das.api.DasSourceRegistryI;
36 import jalview.ws.seqfetcher.DbSourceProxy;
38 import java.awt.BorderLayout;
40 import java.awt.event.ActionEvent;
41 import java.awt.event.ActionListener;
42 import java.awt.event.KeyAdapter;
43 import java.awt.event.KeyEvent;
44 import java.util.ArrayList;
45 import java.util.Arrays;
46 import java.util.Iterator;
47 import java.util.List;
49 import javax.swing.JButton;
50 import javax.swing.JCheckBox;
51 import javax.swing.JInternalFrame;
52 import javax.swing.JLabel;
53 import javax.swing.JOptionPane;
54 import javax.swing.JPanel;
55 import javax.swing.JScrollPane;
56 import javax.swing.JTextArea;
57 import javax.swing.SwingConstants;
58 import javax.swing.tree.DefaultMutableTreeNode;
60 public class SequenceFetcher extends JPanel implements Runnable
62 JLabel dbeg = new JLabel();
64 JDatabaseTree database;
68 JLabel jLabel1 = new JLabel();
70 JCheckBox replacePunctuation = new JCheckBox();
72 JButton ok = new JButton();
74 JButton clear = new JButton();
76 JButton example = new JButton();
78 JButton close = new JButton();
80 JPanel jPanel1 = new JPanel();
82 JTextArea textArea = new JTextArea();
84 JScrollPane jScrollPane1 = new JScrollPane();
86 JPanel jPanel2 = new JPanel();
88 JPanel jPanel3 = new JPanel();
90 JPanel jPanel4 = new JPanel();
92 BorderLayout borderLayout1 = new BorderLayout();
94 BorderLayout borderLayout2 = new BorderLayout();
96 BorderLayout borderLayout3 = new BorderLayout();
100 IProgressIndicator guiWindow;
102 AlignFrame alignFrame;
106 final String noDbSelected = "-- Select Database --";
108 private static jalview.ws.SequenceFetcher sfetch = null;
110 private static long lastDasSourceRegistry = -3;
112 private static DasSourceRegistryI dasRegistry = null;
114 private static boolean _initingFetcher = false;
116 private static Thread initingThread = null;
118 int debounceTrap = 0;
120 public JTextArea getTextArea()
126 * Blocking method that initialises and returns the shared instance of the
127 * SequenceFetcher client
130 * - where the initialisation delay message should be shown
131 * @return the singleton instance of the sequence fetcher client
133 public static jalview.ws.SequenceFetcher getSequenceFetcherSingleton(
134 final IProgressIndicator guiWindow)
136 if (_initingFetcher && initingThread != null && initingThread.isAlive())
138 if (guiWindow != null)
143 .getString("status.waiting_sequence_database_fetchers_init"),
144 Thread.currentThread().hashCode());
146 // initting happening on another thread - so wait around to see if it
148 while (_initingFetcher && initingThread != null
149 && initingThread.isAlive())
154 } catch (Exception e)
159 if (guiWindow != null)
164 .getString("status.waiting_sequence_database_fetchers_init"),
165 Thread.currentThread().hashCode());
169 || dasRegistry != Cache.getDasSourceRegistry()
170 || lastDasSourceRegistry != (Cache.getDasSourceRegistry()
171 .getDasRegistryURL() + Cache
172 .getDasSourceRegistry().getLocalSourceString())
175 _initingFetcher = true;
176 initingThread = Thread.currentThread();
178 * give a visual indication that sequence fetcher construction is occuring
180 if (guiWindow != null)
182 guiWindow.setProgressBar(MessageManager
183 .getString("status.init_sequence_database_fetchers"),
184 Thread.currentThread().hashCode());
186 dasRegistry = Cache.getDasSourceRegistry();
187 dasRegistry.refreshSources();
189 jalview.ws.SequenceFetcher sf = new jalview.ws.SequenceFetcher();
190 if (guiWindow != null)
192 guiWindow.setProgressBar(null, Thread.currentThread().hashCode());
194 lastDasSourceRegistry = (dasRegistry.getDasRegistryURL() + dasRegistry
195 .getLocalSourceString()).hashCode();
197 _initingFetcher = false;
198 initingThread = null;
203 private IProgressIndicator progressIndicator;
205 public SequenceFetcher(IProgressIndicator guiIndic)
207 this.progressIndicator = guiIndic;
208 final SequenceFetcher us = this;
209 // launch initialiser thread
210 Thread sf = new Thread(new Runnable()
216 if (getSequenceFetcherSingleton(progressIndicator) != null)
218 us.initGui(progressIndicator);
222 javax.swing.SwingUtilities.invokeLater(new Runnable()
228 .showInternalMessageDialog(
231 .getString("warn.couldnt_create_sequence_fetcher_client"),
233 .getString("label.couldnt_create_sequence_fetcher"),
234 JOptionPane.ERROR_MESSAGE);
238 // raise warning dialog
245 private class DatabaseAuthority extends DefaultMutableTreeNode
250 private class DatabaseSource extends DefaultMutableTreeNode
256 * called by thread spawned by constructor
260 private void initGui(IProgressIndicator guiWindow)
262 this.guiWindow = guiWindow;
263 if (guiWindow instanceof AlignFrame)
265 alignFrame = (AlignFrame) guiWindow;
267 database = new JDatabaseTree(sfetch);
271 database.waitForInput();
272 } catch (Exception ex)
274 ex.printStackTrace();
277 frame = new JInternalFrame();
278 frame.setContentPane(this);
279 if (Platform.isAMac())
281 Desktop.addInternalFrame(frame, getFrameTitle(), false, 400, 240);
285 Desktop.addInternalFrame(frame, getFrameTitle(), false, 400, 180);
289 private String getFrameTitle()
291 return ((alignFrame == null) ? MessageManager
292 .getString("label.new_sequence_fetcher") : MessageManager
293 .getString("label.additional_sequence_fetcher"));
296 private void jbInit() throws Exception
298 this.setLayout(borderLayout2);
300 database.setFont(JvSwingUtils.getLabelFont());
301 dbeg.setFont(new java.awt.Font("Verdana", Font.BOLD, 11));
302 jLabel1.setFont(new java.awt.Font("Verdana", Font.ITALIC, 11));
303 jLabel1.setHorizontalAlignment(SwingConstants.CENTER);
304 jLabel1.setText(MessageManager
305 .getString("label.separate_multiple_accession_ids"));
307 replacePunctuation.setHorizontalAlignment(SwingConstants.CENTER);
309 .setFont(new java.awt.Font("Verdana", Font.ITALIC, 11));
310 replacePunctuation.setText(MessageManager
311 .getString("label.replace_commas_semicolons"));
312 ok.setText(MessageManager.getString("action.ok"));
313 ok.addActionListener(new ActionListener()
316 public void actionPerformed(ActionEvent e)
318 ok_actionPerformed();
321 clear.setText(MessageManager.getString("action.clear"));
322 clear.addActionListener(new ActionListener()
325 public void actionPerformed(ActionEvent e)
327 clear_actionPerformed();
331 example.setText(MessageManager.getString("label.example"));
332 example.addActionListener(new ActionListener()
335 public void actionPerformed(ActionEvent e)
337 example_actionPerformed();
340 close.setText(MessageManager.getString("action.close"));
341 close.addActionListener(new ActionListener()
344 public void actionPerformed(ActionEvent e)
346 close_actionPerformed(e);
349 textArea.setFont(JvSwingUtils.getLabelFont());
350 textArea.setLineWrap(true);
351 textArea.addKeyListener(new KeyAdapter()
354 public void keyPressed(KeyEvent e)
356 if (e.getKeyCode() == KeyEvent.VK_ENTER)
358 ok_actionPerformed();
362 jPanel3.setLayout(borderLayout1);
363 borderLayout1.setVgap(5);
365 jPanel1.add(example);
368 jPanel3.add(jPanel2, java.awt.BorderLayout.CENTER);
369 jPanel2.setLayout(borderLayout3);
370 databaseButt = /*database.getDatabaseSelectorButton();
371 final JButton viewdbs =*/new JButton(
372 MessageManager.getString("action.select_ddbb"));
373 databaseButt.addActionListener(new ActionListener()
377 public void actionPerformed(ActionEvent arg0)
380 database.showDialog();
383 databaseButt.setFont(JvSwingUtils.getLabelFont());
384 database.addActionListener(new ActionListener()
387 public void actionPerformed(ActionEvent e)
390 String currentSelection = database.getSelectedItem();
391 if (currentSelection == null)
393 close_actionPerformed(null);
398 if (currentSelection.equalsIgnoreCase("pdb")
399 && (database.action == KeyEvent.VK_ENTER || ((debounceTrap % 2) == 0)))
403 else if (currentSelection.equalsIgnoreCase("uniprot")
404 && (database.action == KeyEvent.VK_ENTER || ((debounceTrap % 2) == 0)))
406 uniprotSourceAction();
412 database.action = -1;
417 jPanel2.add(databaseButt, java.awt.BorderLayout.NORTH);
418 jPanel2.add(dbeg, java.awt.BorderLayout.CENTER);
419 JPanel jPanel2a = new JPanel(new BorderLayout());
420 jPanel2a.add(jLabel1, java.awt.BorderLayout.NORTH);
421 jPanel2a.add(replacePunctuation, java.awt.BorderLayout.SOUTH);
422 jPanel2.add(jPanel2a, java.awt.BorderLayout.SOUTH);
423 // jPanel2.setPreferredSize(new Dimension())
424 jPanel3.add(jScrollPane1, java.awt.BorderLayout.CENTER);
425 this.add(jPanel1, java.awt.BorderLayout.SOUTH);
426 this.add(jPanel3, java.awt.BorderLayout.CENTER);
427 this.add(jPanel2, java.awt.BorderLayout.NORTH);
428 jScrollPane1.getViewport().add(textArea);
431 private void pdbSourceAction()
433 databaseButt.setText(database.getSelectedItem());
434 new PDBFTSPanel(this);
438 private void uniprotSourceAction()
440 databaseButt.setText(database.getSelectedItem());
441 new UniprotFTSPanel(this);
444 private void otherSourceAction()
448 databaseButt.setText(database.getSelectedItem()
449 + (database.getSelectedSources().size() > 1 ? " (and "
450 + database.getSelectedSources().size() + " others)"
452 String eq = database.getExampleQueries();
453 dbeg.setText(MessageManager.formatMessage(
454 "label.example_query_param", new String[] { eq }));
455 boolean enablePunct = !(eq != null && eq.indexOf(",") > -1);
456 for (DbSourceProxy dbs : database.getSelectedSources())
458 if (dbs instanceof jalview.ws.dbsources.das.datamodel.DasSequenceSource)
464 replacePunctuation.setEnabled(enablePunct);
466 } catch (Exception ex)
469 replacePunctuation.setEnabled(true);
474 protected void example_actionPerformed()
476 DbSourceProxy db = null;
479 textArea.setText(database.getExampleQueries());
480 } catch (Exception ex)
486 protected void clear_actionPerformed()
488 textArea.setText("");
492 public void close_actionPerformed(ActionEvent e)
496 frame.setClosed(true);
497 } catch (Exception ex)
502 public void ok_actionPerformed()
504 databaseButt.setEnabled(false);
505 example.setEnabled(false);
506 textArea.setEnabled(false);
507 ok.setEnabled(false);
508 close.setEnabled(false);
510 Thread worker = new Thread(this);
514 private void resetDialog()
516 databaseButt.setEnabled(true);
517 example.setEnabled(true);
518 textArea.setEnabled(true);
520 close.setEnabled(true);
527 if (!database.hasSelection())
529 error += "Please select the source database\n";
531 // TODO: make this transformation more configurable
532 com.stevesoft.pat.Regex empty;
533 if (replacePunctuation.isEnabled() && replacePunctuation.isSelected())
535 empty = new com.stevesoft.pat.Regex(
536 // replace commas and spaces with a semicolon
537 "(\\s|[,; ])+", ";");
541 // just turn spaces and semicolons into single semicolons
542 empty = new com.stevesoft.pat.Regex("(\\s|[; ])+", ";");
544 textArea.setText(empty.replaceAll(textArea.getText()));
545 // see if there's anthing to search with
546 if (!new com.stevesoft.pat.Regex("[A-Za-z0-9_.]").search(textArea
549 error += "Please enter a (semi-colon separated list of) database id(s)";
551 if (error.length() > 0)
553 showErrorMessage(error);
557 // TODO: Refactor to GUI independent code and write tests.
558 // indicate if successive sources should be merged into one alignment.
559 boolean addToLast = false;
560 List<String> aresultq = new ArrayList<String>();
561 List<String> presultTitle = new ArrayList<String>();
562 List<AlignmentI> presult = new ArrayList<AlignmentI>();
563 List<AlignmentI> aresult = new ArrayList<AlignmentI>();
564 Iterator<DbSourceProxy> proxies = database.getSelectedSources()
567 List<String> nextFetch = Arrays.asList(qries = textArea.getText()
569 Iterator<String> en = Arrays.asList(new String[0]).iterator();
570 int nqueries = qries.length;
572 FeatureSettingsModelI preferredFeatureColours = null;
573 while (proxies.hasNext() && (en.hasNext() || nextFetch.size() > 0))
575 if (!en.hasNext() && nextFetch.size() > 0)
577 en = nextFetch.iterator();
578 nqueries = nextFetch.size();
579 // save the remaining queries in the original array
580 qries = nextFetch.toArray(new String[nqueries]);
581 nextFetch = new ArrayList<String>();
584 DbSourceProxy proxy = proxies.next();
589 .setProgressBar(MessageManager.formatMessage(
590 "status.fetching_sequence_queries_from",
592 Integer.valueOf(nqueries).toString(),
593 proxy.getDbName() }), Thread.currentThread()
595 if (proxy.getMaximumQueryCount() == 1)
598 * proxy only handles one accession id at a time
602 String acc = en.next();
603 if (!fetchSingleAccession(proxy, acc, aresultq, aresult))
612 * proxy can fetch multiple accessions at one time
614 fetchMultipleAccessions(proxy, en, aresultq, aresult, nextFetch);
616 } catch (Exception e)
618 showErrorMessage("Error retrieving " + textArea.getText()
619 + " from " + database.getSelectedItem());
621 // +="Couldn't retrieve sequences from "+database.getSelectedItem();
622 System.err.println("Retrieval failed for source ='"
623 + database.getSelectedItem() + "' and query\n'"
624 + textArea.getText() + "'\n");
626 } catch (OutOfMemoryError e)
628 showErrorMessage("Out of Memory when retrieving "
631 + database.getSelectedItem()
632 + "\nPlease see the Jalview FAQ for instructions for increasing the memory available to Jalview.\n");
636 showErrorMessage("Serious Error retrieving " + textArea.getText()
637 + " from " + database.getSelectedItem());
641 // Stack results ready for opening in alignment windows
642 if (aresult != null && aresult.size() > 0)
644 FeatureSettingsModelI proxyColourScheme = proxy
645 .getFeatureColourScheme();
646 if (proxyColourScheme != null)
648 preferredFeatureColours = proxyColourScheme;
651 AlignmentI ar = null;
652 if (proxy.isAlignmentSource())
655 // new window for each result
656 while (aresult.size() > 0)
658 presult.add(aresult.remove(0));
659 presultTitle.add(aresultq.remove(0) + " "
660 + getDefaultRetrievalTitle());
666 if (addToLast && presult.size() > 0)
668 ar = presult.remove(presult.size() - 1);
669 titl = presultTitle.remove(presultTitle.size() - 1);
671 // concatenate all results in one window
672 while (aresult.size() > 0)
676 ar = aresult.remove(0);
680 ar.append(aresult.remove(0));
685 presultTitle.add(titl);
688 guiWindow.setProgressBar(MessageManager
689 .getString("status.finshed_querying"), Thread.currentThread()
692 guiWindow.setProgressBar(
693 (presult.size() > 0) ? MessageManager
694 .getString("status.parsing_results") : MessageManager
695 .getString("status.processing"), Thread.currentThread()
698 while (presult.size() > 0)
700 parseResult(presult.remove(0), presultTitle.remove(0), null,
701 preferredFeatureColours);
703 // only remove visual delay after we finished parsing.
704 guiWindow.setProgressBar(null, Thread.currentThread().hashCode());
705 if (nextFetch.size() > 0)
707 StringBuffer sb = new StringBuffer();
708 sb.append("Didn't retrieve the following "
709 + (nextFetch.size() == 1 ? "query" : nextFetch.size()
710 + " queries") + ": \n");
711 int l = sb.length(), lr = 0;
712 for (String s : nextFetch)
714 if (l != sb.length())
718 if (lr - sb.length() > 40)
724 showErrorMessage(sb.toString());
730 * Tries to fetch one or more accession ids from the database proxy
734 * the queries to fetch
736 * a successful queries list to add to
738 * a list of retrieved alignments to add to
740 * failed queries are added to this list
743 void fetchMultipleAccessions(DbSourceProxy proxy,
744 Iterator<String> accessions, List<String> aresultq,
745 List<AlignmentI> aresult, List<String> nextFetch)
748 StringBuilder multiacc = new StringBuilder();
749 List<String> tosend = new ArrayList<String>();
750 while (accessions.hasNext())
752 String nel = accessions.next();
754 multiacc.append(nel);
755 if (accessions.hasNext())
757 multiacc.append(proxy.getAccessionSeparator());
763 String query = multiacc.toString();
764 AlignmentI rslt = proxy.getSequenceRecords(query);
765 if (rslt == null || rslt.getHeight() == 0)
767 // no results - pass on all queries to next source
768 nextFetch.addAll(tosend);
774 if (tosend.size() > 1)
776 checkResultForQueries(rslt, tosend, nextFetch, proxy);
779 } catch (OutOfMemoryError oome)
781 new OOMWarning("fetching " + multiacc + " from "
782 + database.getSelectedItem(), oome, this);
787 * Query for a single accession id via the database proxy
792 * a list of successful queries to add to
794 * a list of retrieved alignments to add to
795 * @return true if the fetch was successful, else false
797 boolean fetchSingleAccession(DbSourceProxy proxy, String accession,
798 List<String> aresultq, List<AlignmentI> aresult)
800 boolean success = false;
807 // give the server a chance to breathe
809 } catch (Exception e)
815 AlignmentI indres = null;
818 indres = proxy.getSequenceRecords(accession);
819 } catch (OutOfMemoryError oome)
821 new OOMWarning("fetching " + accession + " from "
822 + proxy.getDbName(), oome, this);
826 aresultq.add(accession);
830 } catch (Exception e)
833 "Error retrieving " + accession
834 + " from " + proxy.getDbName(), e);
840 * Checks which of the queries were successfully retrieved by searching the
841 * DBRefs of the retrieved sequences for a match. Any not found are added to
842 * the 'nextFetch' list.
849 void checkResultForQueries(AlignmentI rslt, List<String> queries,
850 List<String> nextFetch, DbSourceProxy proxy)
852 SequenceI[] rs = rslt.getSequencesArray();
854 for (String q : queries)
856 DBRefEntry dbr = new DBRefEntry();
857 dbr.setSource(proxy.getDbSource());
858 dbr.setVersion(null);
859 String accId = proxy.getAccessionIdFromQuery(q);
860 dbr.setAccessionId(accId);
861 boolean rfound = false;
862 for (int r = 0; r < rs.length; r++)
866 List<DBRefEntry> found = DBRefUtils.searchRefs(rs[r].getDBRefs(),
868 if (!found.isEmpty())
884 * @return a standard title for any results retrieved using the currently
885 * selected source and settings
887 public String getDefaultRetrievalTitle()
889 return "Retrieved from " + database.getSelectedItem();
892 AlignmentI parseResult(AlignmentI al, String title,
893 String currentFileFormat,
894 FeatureSettingsModelI preferredFeatureColours)
897 if (al != null && al.getHeight() > 0)
901 title = getDefaultRetrievalTitle();
903 if (alignFrame == null)
905 AlignFrame af = new AlignFrame(al, AlignFrame.DEFAULT_WIDTH,
906 AlignFrame.DEFAULT_HEIGHT);
907 if (currentFileFormat != null)
909 af.currentFileFormat = currentFileFormat; // WHAT IS THE DEFAULT
911 // NON-FormatAdapter Sourced
915 SequenceFeature[] sfs = null;
916 List<SequenceI> alsqs;
917 synchronized (alsqs = al.getSequences())
919 for (SequenceI sq : alsqs)
921 if ((sfs = sq.getSequenceFeatures()) != null)
925 af.setShowSeqFeatures(true);
933 if (preferredFeatureColours != null)
935 af.getViewport().applyFeaturesStyle(preferredFeatureColours);
937 if (Cache.getDefault("HIDE_INTRONS", true))
939 af.hideFeatureColumns(SequenceOntologyI.EXON, false);
942 Desktop.addInternalFrame(af, title, AlignFrame.DEFAULT_WIDTH,
943 AlignFrame.DEFAULT_HEIGHT);
945 af.statusBar.setText(MessageManager
946 .getString("label.successfully_pasted_alignment_file"));
950 af.setMaximum(Cache.getDefault("SHOW_FULLSCREEN",
952 } catch (Exception ex)
958 alignFrame.viewport.addAlignment(al, title);
964 void showErrorMessage(final String error)
967 javax.swing.SwingUtilities.invokeLater(new Runnable()
972 JOptionPane.showInternalMessageDialog(Desktop.desktop, error,
973 MessageManager.getString("label.error_retrieving_data"),
974 JOptionPane.WARNING_MESSAGE);
979 public IProgressIndicator getProgressIndicator()
981 return progressIndicator;
984 public void setProgressIndicator(IProgressIndicator progressIndicator)
986 this.progressIndicator = progressIndicator;
990 * Make this panel visible (after a selection has been made in the database
995 frame.setVisible(true);
999 * Hide this panel (on clicking the database button to open the database
1004 frame.setVisible(false);