-<p><strong>What's new ?</strong></p>
-<p>The Jalview 2.6.1 release fixes a number of minor bugs affecting
-Jalview operation, including issues affecting the import and export of
-PIR files and working with multiple multiple structure superpositions.
-For full details see the <a href="releases.html#Jalview2.6.1">Jalview
-2.6.1 release history</a>.</p>
-<p><strong>Highlights in Jalview Version 2.6</strong></p>
-<ul>
- <li><a href="webServices/JABAWS.html">JABA Web Services</a> for
- multiple alignment using:
- <ul>
- <li>ClustalW</li>
- <li>MAFFT</li>
- <li>Muscle</li>
- <li>ProbCons</li>
- <li>T-COFFEE</li>
- </ul>
- </li>
- <li>User modifiable alignment service parameters</li>
- <li>Visualization of superposed structures associated with protein
- or nucleotide sequence alignments.</li>
- <li>Export coordinates and projection as CSV from PCA viewer</li>
- <li>New Purine/Pyrimidine colour scheme</li>
- <li>Colouring of RNA secondary structure by helices. See <a href="na/index.html">Nucleic Acid Support</a></li>
-
-</ul>
-
-<p><strong>Issues Resolved (a select list - see release
-history for details)</strong></p>
-<ul>
+ <p>
+ <strong>What's new ?</strong>
+ </p>
+ <p>
+ Jalview 2.10 is the next major release in the Jalview 2 series. Full
+ details are in the <a href="releases.html#Jalview.2.10.0">Jalview
+ 2.10 Release Notes</a>, but the highlights are below.
+ </p>
+ <p>
+ <strong>Highlights in Jalview 2.10</strong>
+ <ul>
+ <li><strong>Ensembl sequence fetcher.</strong> Annotated Genes,
+ transcripts and proteins can be retrieved via Jalview's new <a
+ href="features/ensemblsequencefetcher.html">Ensembl REST
+ client</a>. Support for import of Ensembl data also allows:
+ <ul>
+ <li><strong>Sequence variant data.</strong> Jalview
+ propagates variant annotation imported via Ensembl onto
+ protein products, complete with associated metadata such as
+ clinical significance.</li>
+ <li><strong>Aligned locus view.</strong> Transcripts
+ retrieved for a gene identifier via the Ensembl or
+ EnsemblGenomes sequence databases are automatically aligned to
+ their reference genome.</li>
+ </ul></li>
+ <li><strong>Working with structures.</strong>
+ <ul>
+ <li><strong>More accurate structure mappings.</strong>
+ Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI)
+ to <a href="features/siftsmapping.html">match structures
+ to UniProt sequences</a>, even for structures containing
+ multiple copies of a sequence.</li>
+ <li><strong>Import structures as mmCIF</strong>. Jalview
+ now downloads data from the EMBL-EBI's PDBe site as <a href="features/mmcif.html">mmCIF</a>.
+ This allows very large structures to be imported, such as the HIV virus capsid assembly.</li>
+ </ul></li>
+ <li><strong>UniProt Free Text Search</strong>. The new search
+ dialog for UniProt allows you to browse and retrieve sequences
+ from UniProt with free-text search and more structured queries</li>
+ <li><strong>Reference sequence based alignment
+ visualisation.</strong>. When a reference sequence is defined for the
+ alignment, the alignment column ruler is now numbered according to
+ the reference sequence. The reference sequence for alignment views
+ can also be saved and restored from Jalview projects.</li>
+ <li></li>
+ </ul>