kepp only one dup min gt
[jalview.git] / forester / java / src / org / forester / application / gsdi.java
index 323d20d..17dbf7e 100644 (file)
 // Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA
 //
 // Contact: phylosoft @ gmail . com
-// WWW: www.phylosoft.org/forester
+// WWW: https://sites.google.com/site/cmzmasek/home/software/forester
 
 package org.forester.application;
 
 import java.io.File;
 import java.io.IOException;
+import java.text.SimpleDateFormat;
 import java.util.ArrayList;
 import java.util.Date;
 import java.util.List;
+import java.util.SortedMap;
+import java.util.SortedSet;
+import java.util.TreeMap;
+import java.util.TreeSet;
 
+import org.forester.io.parsers.nhx.NHXParser.TAXONOMY_EXTRACTION;
+import org.forester.io.parsers.phyloxml.PhyloXmlDataFormatException;
 import org.forester.io.parsers.phyloxml.PhyloXmlParser;
 import org.forester.io.writers.PhylogenyWriter;
 import org.forester.phylogeny.Phylogeny;
+import org.forester.phylogeny.PhylogenyMethods;
+import org.forester.phylogeny.PhylogenyNode;
 import org.forester.phylogeny.factories.ParserBasedPhylogenyFactory;
 import org.forester.phylogeny.factories.PhylogenyFactory;
 import org.forester.sdi.GSDI;
-import org.forester.sdi.SDI;
-import org.forester.sdi.SDIse;
+import org.forester.sdi.GSDII;
+import org.forester.sdi.GSDIR;
+import org.forester.sdi.SDIException;
+import org.forester.sdi.SDIutil;
+import org.forester.sdi.SDIutil.ALGORITHM;
 import org.forester.util.CommandLineArguments;
+import org.forester.util.EasyWriter;
+import org.forester.util.ForesterConstants;
 import org.forester.util.ForesterUtil;
 
 public final class gsdi {
 
-    final static private String STRIP_OPTION             = "s";
-    final static private String GSDI_OPTION              = "g";
-    final static private String MOST_PARSIMONIOUS_OPTION = "m";
-    final static private String HELP_OPTION_1            = "help";
-    final static private String HELP_OPTION_2            = "h";
-    final static private String DEFAULT_OUTFILE          = "sdi_out.xml";
-    final static private String PRG_NAME                 = "gsdi";
-    final static private String PRG_VERSION              = "0.4";
-    final static private String PRG_DATE                 = "120607";
-    final static private String PRG_DESC                 = "general speciation duplication inference";
-    final static private String E_MAIL                   = "phylosoft@gmail.com";
-    final static private String WWW                      = "www.phylosoft.org/forester/";
+    final static public boolean REPLACE_UNDERSCORES_IN_NH_SPECIES_TREE = true;
+    final static private String ALLOW_STRIPPING_OF_GENE_TREE_OPTION    = "g";
+    final static private String GSDIR_OPTION                           = "r";
+    final static private String MOST_PARSIMONIOUS_OPTION               = "m";
+    final static private String GUESS_FORMAT_OF_SPECIES_TREE           = "q";
+    final static private String HELP_OPTION_1                          = "help";
+    final static private String HELP_OPTION_2                          = "h";
+    final static private String SUFFIX_FOR_SPECIES_TREE_USED           = "_species_tree_used.xml";
+    final static private String LOGFILE_SUFFIX                         = "_gsdi_log.txt";
+    final static private String REMAPPED_SUFFIX                        = "_gsdi_remapped.txt";
+    final static private String PRG_NAME                               = "gsdi";
+    final static private String PRG_VERSION                            = "1.000";
+    final static private String PRG_DATE                               = "120629";
+    final static private String PRG_DESC                               = "general speciation duplication inference";
+    final static private String E_MAIL                                 = "phylosoft@gmail.com";
+    final static private String WWW                                    = "www.phylosoft.org/forester";
 
     public static void main( final String args[] ) {
-        ForesterUtil.printProgramInformation( PRG_NAME,
-                                              PRG_DESC,
-                                              PRG_VERSION,
-                                              PRG_DATE,
-                                              E_MAIL,
-                                              WWW,
-                                              ForesterUtil.getForesterLibraryInformation() );
-        CommandLineArguments cla = null;
         try {
-            cla = new CommandLineArguments( args );
+            ForesterUtil.printProgramInformation( PRG_NAME,
+                                                  PRG_DESC,
+                                                  PRG_VERSION,
+                                                  PRG_DATE,
+                                                  E_MAIL,
+                                                  WWW,
+                                                  ForesterUtil.getForesterLibraryInformation() );
+            CommandLineArguments cla = null;
+            try {
+                cla = new CommandLineArguments( args );
+            }
+            catch ( final Exception e ) {
+                ForesterUtil.fatalError( PRG_NAME, e.getMessage() );
+            }
+            if ( cla.isOptionSet( gsdi.HELP_OPTION_1 ) || cla.isOptionSet( gsdi.HELP_OPTION_2 ) ) {
+                System.out.println();
+                gsdi.print_help();
+                System.exit( 0 );
+            }
+            else if ( ( args.length < 2 ) || ( cla.getNumberOfNames() != 3 ) ) {
+                System.out.println();
+                System.out.println( "Wrong number of arguments." );
+                System.out.println();
+                gsdi.print_help();
+                System.exit( -1 );
+            }
+            final List<String> allowed_options = new ArrayList<String>();
+            allowed_options.add( gsdi.GSDIR_OPTION );
+            allowed_options.add( gsdi.GUESS_FORMAT_OF_SPECIES_TREE );
+            allowed_options.add( gsdi.MOST_PARSIMONIOUS_OPTION );
+            allowed_options.add( gsdi.ALLOW_STRIPPING_OF_GENE_TREE_OPTION );
+            final String dissallowed_options = cla.validateAllowedOptionsAsString( allowed_options );
+            if ( dissallowed_options.length() > 0 ) {
+                ForesterUtil.fatalError( gsdi.PRG_NAME, "unknown option(s): " + dissallowed_options );
+            }
+            execute( cla );
         }
-        catch ( final Exception e ) {
-            ForesterUtil.fatalError( PRG_NAME, e.getMessage() );
-        }
-        if ( cla.isOptionSet( gsdi.HELP_OPTION_1 ) || cla.isOptionSet( gsdi.HELP_OPTION_2 ) ) {
-            System.out.println();
-            gsdi.print_help();
-            System.exit( 0 );
-        }
-        else if ( ( args.length < 2 ) || ( cla.getNumberOfNames() < 2 ) || ( cla.getNumberOfNames() > 3 ) ) {
-            System.out.println();
-            System.out.println( "Wrong number of arguments." );
-            System.out.println();
-            gsdi.print_help();
-            System.exit( -1 );
-        }
-        final List<String> allowed_options = new ArrayList<String>();
-        allowed_options.add( gsdi.STRIP_OPTION );
-        allowed_options.add( gsdi.GSDI_OPTION );
-        allowed_options.add( gsdi.MOST_PARSIMONIOUS_OPTION );
-        final String dissallowed_options = cla.validateAllowedOptionsAsString( allowed_options );
-        if ( dissallowed_options.length() > 0 ) {
-            ForesterUtil.fatalError( gsdi.PRG_NAME, "unknown option(s): " + dissallowed_options );
-        }
-        boolean use_sdise = true;
-        boolean strip = false;
-        boolean most_parsimonous_duplication_model = false;
-        if ( cla.isOptionSet( gsdi.STRIP_OPTION ) ) {
-            strip = true;
+        catch ( final IOException e ) {
+            ForesterUtil.fatalError( gsdi.PRG_NAME, e.getMessage() );
         }
-        if ( cla.isOptionSet( gsdi.GSDI_OPTION ) ) {
-            use_sdise = false;
+    }
+
+    private static void execute( final CommandLineArguments cla ) throws IOException {
+        ALGORITHM base_algorithm = ALGORITHM.GSDI;
+        boolean most_parsimonous_duplication_model = false;
+        boolean allow_stripping_of_gene_tree = false;
+        if ( cla.isOptionSet( gsdi.GSDIR_OPTION ) ) {
+            base_algorithm = ALGORITHM.GSDIR;
         }
         if ( cla.isOptionSet( gsdi.MOST_PARSIMONIOUS_OPTION ) ) {
-            if ( use_sdise ) {
-                ForesterUtil.fatalError( gsdi.PRG_NAME, "Can only use most parsimonious duplication mode with GSDI" );
+            if ( base_algorithm == ALGORITHM.SDI ) {
+                ForesterUtil.fatalError( gsdi.PRG_NAME, "Cannot use most parsimonious duplication mode with SDI" );
             }
             most_parsimonous_duplication_model = true;
         }
+        if ( cla.isOptionSet( gsdi.ALLOW_STRIPPING_OF_GENE_TREE_OPTION ) ) {
+            if ( base_algorithm == ALGORITHM.SDI ) {
+                ForesterUtil.fatalError( gsdi.PRG_NAME, "Cannot allow stripping of gene tree with SDI" );
+            }
+            allow_stripping_of_gene_tree = true;
+        }
         Phylogeny species_tree = null;
         Phylogeny gene_tree = null;
         File gene_tree_file = null;
         File species_tree_file = null;
         File out_file = null;
+        File log_file = null;
+        EasyWriter log_writer = null;
         try {
             gene_tree_file = cla.getFile( 0 );
             species_tree_file = cla.getFile( 1 );
-            if ( cla.getNumberOfNames() == 3 ) {
-                out_file = cla.getFile( 2 );
-            }
-            else {
-                out_file = new File( gsdi.DEFAULT_OUTFILE );
-            }
+            out_file = cla.getFile( 2 );
+            log_file = new File( ForesterUtil.removeSuffix( out_file.toString() ) + LOGFILE_SUFFIX );
         }
         catch ( final IllegalArgumentException e ) {
             ForesterUtil.fatalError( gsdi.PRG_NAME, "error in command line: " + e.getMessage() );
@@ -134,113 +163,290 @@ public final class gsdi {
         if ( ForesterUtil.isWritableFile( out_file ) != null ) {
             ForesterUtil.fatalError( gsdi.PRG_NAME, ForesterUtil.isWritableFile( out_file ) );
         }
+        if ( ForesterUtil.isWritableFile( log_file ) != null ) {
+            ForesterUtil.fatalError( gsdi.PRG_NAME, ForesterUtil.isWritableFile( log_file ) );
+        }
         try {
-            final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            species_tree = factory.create( species_tree_file, new PhyloXmlParser() )[ 0 ];
+            log_writer = ForesterUtil.createEasyWriter( log_file );
         }
         catch ( final IOException e ) {
-            ForesterUtil.fatalError( gsdi.PRG_NAME,
-                                     "Failed to read species tree from [" + gene_tree_file + "]: " + e.getMessage() );
+            ForesterUtil.fatalError( gsdi.PRG_NAME, "Failed to create [" + log_file + "]: " + e.getMessage() );
         }
         try {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
             gene_tree = factory.create( gene_tree_file, new PhyloXmlParser() )[ 0 ];
         }
         catch ( final IOException e ) {
-            ForesterUtil.fatalError( gsdi.PRG_NAME,
-                                     "Failed to read gene tree from [" + gene_tree_file + "]: " + e.getMessage() );
+            fatalError( "error",
+                        "failed to read gene tree from [" + gene_tree_file + "]: " + e.getMessage(),
+                        log_writer );
+        }
+        try {
+            species_tree = SDIutil.parseSpeciesTree( gene_tree,
+                                                     species_tree_file,
+                                                     REPLACE_UNDERSCORES_IN_NH_SPECIES_TREE,
+                                                     true,
+                                                     TAXONOMY_EXTRACTION.NO );
+        }
+        catch ( final PhyloXmlDataFormatException e ) {
+            fatalError( "user error",
+                        "failed to transfer general node name, in [" + species_tree_file + "]: " + e.getMessage(),
+                        log_writer );
+        }
+        catch ( final SDIException e ) {
+            fatalError( "user error", e.getMessage(), log_writer );
+        }
+        catch ( final IOException e ) {
+            fatalError( "error",
+                        "Failed to read species tree from [" + species_tree_file + "]: " + e.getMessage(),
+                        log_writer );
         }
         gene_tree.setRooted( true );
         species_tree.setRooted( true );
         if ( !gene_tree.isCompletelyBinary() ) {
-            ForesterUtil.fatalError( gsdi.PRG_NAME, "gene tree (\"" + gene_tree_file + "\") is not completely binary." );
+            fatalError( "user error", "gene tree is not completely binary", log_writer );
         }
-        if ( use_sdise ) {
+        if ( base_algorithm == ALGORITHM.SDI ) {
             if ( !species_tree.isCompletelyBinary() ) {
-                ForesterUtil.fatalError( gsdi.PRG_NAME, "species tree (\"" + species_tree_file
-                        + "\") is not completely binary." );
-            }
-        }
-        // For timing.
-        // gene_tree = Helper.createBalancedTree( 10 );
-        // species_tree = Helper.createBalancedTree( 13 );
-        // species_tree = Helper.createUnbalancedTree( 1024 );
-        // gene_tree = Helper.createUnbalancedTree( 8192 );
-        // species_tree = gene_tree.copyTree();
-        // gene_tree = species_tree.copyTree();
-        // Helper.numberSpeciesInOrder( species_tree );
-        // Helper.numberSpeciesInOrder( gene_tree );
-        // Helper.randomizeSpecies( 1, 8192, gene_tree );
-        // Helper.intervalNumberSpecies( gene_tree, 4096 );
-        // Helper.numberSpeciesInDescOrder( gene_tree );
-        System.out.println();
-        System.out.println( "Strip species tree: " + strip );
-        SDI sdi = null;
+                fatalError( "user error",
+                            "species tree is not completely binary, use GSDI or GSDIR instead",
+                            log_writer );
+            }
+        }
+        log_writer.println( PRG_NAME + " - " + PRG_DESC );
+        log_writer.println( "  version         : " + PRG_VERSION );
+        log_writer.println( "  date            : " + PRG_DATE );
+        log_writer.println( "  forester version: " + ForesterConstants.FORESTER_VERSION );
+        log_writer.println();
+        log_writer.println( "Start time                               : "
+                + new SimpleDateFormat( "yyyyMMdd HH:mm:ss" ).format( new Date() ) );
+        System.out.println( "Start time                               : "
+                + new SimpleDateFormat( "yyyyMMdd HH:mm:ss" ).format( new Date() ) );
+        log_writer.println( "Gene tree file                           : " + gene_tree_file.getCanonicalPath() );
+        System.out.println( "Gene tree file                           : " + gene_tree_file.getCanonicalPath() );
+        log_writer.println( "Gene tree name                           : "
+                + ( ForesterUtil.isEmpty( gene_tree.getName() ) ? "" : gene_tree.getName() ) );
+        System.out.println( "Gene tree name                           : "
+                + ( ForesterUtil.isEmpty( gene_tree.getName() ) ? "" : gene_tree.getName() ) );
+        log_writer.println( "Species tree file                        : " + species_tree_file.getCanonicalPath() );
+        System.out.println( "Species tree file                        : " + species_tree_file.getCanonicalPath() );
+        log_writer.println( "Species tree name                        : "
+                + ( ForesterUtil.isEmpty( species_tree.getName() ) ? "" : gene_tree.getName() ) );
+        System.out.println( "Species tree name                        : "
+                + ( ForesterUtil.isEmpty( species_tree.getName() ) ? "" : gene_tree.getName() ) );
+        GSDII gsdii = null;
         final long start_time = new Date().getTime();
         try {
-            if ( use_sdise ) {
-                System.out.println();
-                System.out.println( "Using SDIse algorithm." );
-                sdi = new SDIse( gene_tree, species_tree );
+            if ( base_algorithm == ALGORITHM.GSDI ) {
+                System.out.println( "Algorithm       : GSDI" );
+                log_writer.println( "Algorithm       : GSDI" );
             }
-            else {
-                System.out.println();
-                System.out.println( "Using GSDI algorithm." );
-                System.out.println();
-                System.out.println( "Use most parsimonous duplication model: " + most_parsimonous_duplication_model );
-                sdi = new GSDI( gene_tree, species_tree, most_parsimonous_duplication_model );
+            else if ( base_algorithm == ALGORITHM.GSDIR ) {
+                System.out.println( "Algorithm       : GSDIR" );
+                log_writer.println( "Algorithm       : GSDIR" );
+            }
+            System.out.println( "Use most parsimonous duplication model   : " + most_parsimonous_duplication_model );
+            System.out.println( "Allow stripping of gene tree nodes       : " + allow_stripping_of_gene_tree );
+            log_writer.println( "Use most parsimonous duplication model   : " + most_parsimonous_duplication_model );
+            log_writer.println( "Allow stripping of gene tree nodes       : " + allow_stripping_of_gene_tree );
+            log_writer.flush();
+            if ( base_algorithm == ALGORITHM.GSDI ) {
+                gsdii = new GSDI( gene_tree,
+                                  species_tree,
+                                  most_parsimonous_duplication_model,
+                                  allow_stripping_of_gene_tree,
+                                  true );
             }
+            else if ( base_algorithm == ALGORITHM.GSDIR ) {
+                gsdii = new GSDIR( gene_tree, species_tree, allow_stripping_of_gene_tree, true );
+            }
+        }
+        catch ( final SDIException e ) {
+            fatalError( "user error", e.getLocalizedMessage(), log_writer );
+        }
+        catch ( final IOException e ) {
+            fatalError( "error", e.toString(), log_writer );
+        }
+        catch ( final OutOfMemoryError e ) {
+            ForesterUtil.outOfMemoryError( e );
         }
         catch ( final Exception e ) {
-            ForesterUtil.fatalError( PRG_NAME, e.getLocalizedMessage() );
+            e.printStackTrace();
+            fatalError( "unexpected error", e.toString(), log_writer );
+        }
+        System.out.println( "Running time (excluding I/O)             : " + ( new Date().getTime() - start_time )
+                + "ms" );
+        log_writer.println( "Running time (excluding I/O)             : " + ( new Date().getTime() - start_time )
+                + "ms" );
+        System.out.println( "Mapping based on                         : " + gsdii.getTaxCompBase() );
+        log_writer.println( "Mapping based on                         : " + gsdii.getTaxCompBase() );
+        if ( ( base_algorithm == ALGORITHM.GSDIR ) ) {
+            final GSDIR gsdir = ( GSDIR ) gsdii;
+            System.out.println( "Duplications sum statistics              : " + gsdir.getMinDuplicationsSum() );
+            log_writer.println( "Duplications sum statistics              : " + gsdir.getMinDuplicationsSum() );
         }
-        System.out.println();
-        System.out.println( "Running time (excluding I/O): " + ( new Date().getTime() - start_time ) + "ms" );
         try {
             final PhylogenyWriter writer = new PhylogenyWriter();
-            writer.toPhyloXML( out_file, gene_tree, 1 );
+            if ( base_algorithm == ALGORITHM.GSDIR ) {
+                writer.toPhyloXML( out_file, ( ( GSDIR ) gsdii ).getMinDuplicationsSumGeneTree(), 0 );
+            }
+            else {
+                writer.toPhyloXML( out_file, gene_tree, 0 );
+            }
         }
         catch ( final IOException e ) {
-            ForesterUtil.fatalError( PRG_NAME, "Failed to write to \"" + out_file + "\" [" + e.getMessage() + "]" );
+            ForesterUtil.fatalError( PRG_NAME,
+                                     "Failed to write to [" + out_file.getCanonicalPath() + "]: " + e.getMessage() );
         }
-        System.out.println();
-        System.out.println( "Successfully wrote resulting gene tree to: " + out_file );
-        System.out.println();
-        if ( use_sdise ) {
-            sdi.computeMappingCostL();
-            System.out.println( "Mapping cost                    : " + sdi.computeMappingCostL() );
+        System.out.println( "Wrote resulting gene tree to             : " + out_file.getCanonicalPath() );
+        log_writer.println( "Wrote resulting gene tree to             : " + out_file.getCanonicalPath() );
+        final File species_tree_used_file = new File( ForesterUtil.removeSuffix( out_file.toString() )
+                + SUFFIX_FOR_SPECIES_TREE_USED );
+        try {
+            final PhylogenyWriter writer = new PhylogenyWriter();
+            writer.toPhyloXML( species_tree_used_file, species_tree, 0 );
         }
-        System.out.println( "Number of duplications          : " + sdi.getDuplicationsSum() );
-        if ( !use_sdise && !most_parsimonous_duplication_model ) {
-            System.out.println( "Number of potential duplications: "
-                    + ( ( GSDI ) sdi ).getSpeciationOrDuplicationEventsSum() );
+        catch ( final IOException e ) {
+            ForesterUtil.fatalError( PRG_NAME, "Failed to write to [" + species_tree_used_file.getCanonicalPath()
+                    + "]: " + e.getMessage() );
         }
-        if ( !use_sdise ) {
-            System.out.println( "Number speciations              : " + ( ( GSDI ) sdi ).getSpeciationsSum() );
+        System.out.println( "Wrote (stripped) species tree to         : " + species_tree_used_file.getCanonicalPath() );
+        log_writer.println( "Wrote (stripped) species tree to         : " + species_tree_used_file.getCanonicalPath() );
+        if ( ( gsdii.getReMappedScientificNamesFromGeneTree() != null )
+                && !gsdii.getReMappedScientificNamesFromGeneTree().isEmpty() ) {
+            System.out.println( "Number of gene tree species remapped     : "
+                    + gsdii.getReMappedScientificNamesFromGeneTree().size() );
+            log_writer.println( "Number of gene tree species remapped     : "
+                    + gsdii.getReMappedScientificNamesFromGeneTree().size() );
+            writeToRemappedFile( out_file, gsdii.getReMappedScientificNamesFromGeneTree(), log_writer );
         }
+        System.out.println( "Number of external nodes in gene tree    : " + gene_tree.getNumberOfExternalNodes() );
+        log_writer.println( "Number of external nodes in gene tree    : " + gene_tree.getNumberOfExternalNodes() );
+        System.out.println( "Number of external nodes in species tree : " + species_tree.getNumberOfExternalNodes() );
+        log_writer.println( "Number of external nodes in species tree : " + species_tree.getNumberOfExternalNodes() );
+        final int poly = PhylogenyMethods.countNumberOfPolytomies( species_tree );
+        System.out.println( "Number of polytomies in species tree     : " + poly );
+        log_writer.println( "Number of polytomies in species tree     : " + poly );
+        System.out.println( "External nodes stripped from gene tree   : "
+                + gsdii.getStrippedExternalGeneTreeNodes().size() );
+        log_writer.println( "External nodes stripped from gene tree   : "
+                + gsdii.getStrippedExternalGeneTreeNodes().size() );
+        System.out.println( "External nodes stripped from species tree: " + gsdii.getStrippedSpeciesTreeNodes().size() );
+        log_writer.println( "External nodes stripped from species tree: " + gsdii.getStrippedSpeciesTreeNodes().size() );
         System.out.println();
-    } // main( final String args[] )
+        System.out.println( "Number of speciations                    : " + gsdii.getSpeciationsSum() );
+        log_writer.println( "Number of speciations                    : " + gsdii.getSpeciationsSum() );
+        if ( ( base_algorithm == ALGORITHM.GSDIR ) ) {
+            final GSDIR gsdir = ( GSDIR ) gsdii;
+            System.out.println( "Minimal number of duplications           : " + gsdir.getMinDuplicationsSum() );
+            log_writer.println( "Minimal number of duplications           : " + gsdir.getMinDuplicationsSum() );
+        }
+        else if ( ( base_algorithm == ALGORITHM.GSDI ) ) {
+            final GSDI gsdi = ( GSDI ) gsdii;
+            System.out.println( "Number of duplications                   : " + gsdi.getDuplicationsSum() );
+            log_writer.println( "Number of duplications                   : " + gsdi.getDuplicationsSum() );
+            if ( !most_parsimonous_duplication_model ) {
+                final int u = gsdi.getSpeciationOrDuplicationEventsSum();
+                System.out.println( "Number of potential duplications         : " + u );
+                log_writer.println( "Number of potential duplications         : " + u );
+            }
+        }
+        log_writer.println();
+        printMappedNodesToLog( log_writer, gsdii );
+        log_writer.println();
+        printStrippedGeneTreeNodesToLog( log_writer, gsdii );
+        System.out.println();
+        System.out.println( "Wrote log to                             : " + log_file.getCanonicalPath() );
+        System.out.println();
+        log_writer.close();
+    }
+
+    private static void fatalError( final String type, final String msg, final EasyWriter log_writer ) {
+        try {
+            log_writer.flush();
+            log_writer.println();
+            log_writer.print( type.toUpperCase() + ": " );
+            log_writer.println( msg );
+            log_writer.close();
+        }
+        catch ( final IOException e ) {
+            e.printStackTrace();
+        }
+        ForesterUtil.fatalError( gsdi.PRG_NAME, msg );
+    }
 
     private static void print_help() {
-        System.out.println( "Usage: \"" + gsdi.PRG_NAME
-                + " [-options] <gene tree in phyloXML format> <species tree in phyloXML format> [outfile]\"" );
+        System.out.println( "Usage: " + gsdi.PRG_NAME
+                + " [-options] <gene tree in phyloXML format> <species tree> <outfile>" );
         System.out.println();
         System.out.println( "Options:" );
-        System.out.println( " -" + gsdi.STRIP_OPTION + ": to strip the species tree prior to duplication inference" );
-        System.out.println( " -" + gsdi.GSDI_OPTION
-                + ": to use GSDI algorithm instead of SDIse algorithm (under development, not recommended)" );
-        System.out
-                .println( " -" + gsdi.MOST_PARSIMONIOUS_OPTION + ": use most parimonious duplication model for GSDI: " );
+        System.out.println( " -" + gsdi.ALLOW_STRIPPING_OF_GENE_TREE_OPTION
+                + ": to allow stripping of gene tree nodes without a matching species" );
+        System.out.println( " -" + gsdi.MOST_PARSIMONIOUS_OPTION
+                + ": use most parimonious duplication model for GSDI: " );
         System.out.println( "     assign nodes as speciations which would otherwise be assiged" );
-        System.out.println( "     as unknown because of polytomies in the species tree" );
-        System.out.println();
-        System.out.println( "Species tree:" );
-        System.out.println( " In phyloXML format, with taxonomy data in appropriate fields." );
+        System.out.println( "     as potential duplications due to polytomies in the species tree" );
+        System.out.println( " -" + gsdi.GUESS_FORMAT_OF_SPECIES_TREE
+                + ": to allow species tree in other formats than phyloXML (i.e. Newick, NHX, Nexus)" );
+        System.out.println( " -" + gsdi.GSDIR_OPTION
+                + ": to use GSDIR algorithm instead of GSDI algorithm (re-rooting)" );
         System.out.println();
         System.out.println( "Gene tree:" );
-        System.out.println( " In phyloXM format, with taxonomy and sequence data in appropriate fields." );
+        System.out.println( " in phyloXM format, with taxonomy and sequence data in appropriate fields" );
+        System.out.println();
+        System.out.println( "Species tree:" );
+        System.out.println( " in phyloXML format (unless option -" + gsdi.GUESS_FORMAT_OF_SPECIES_TREE + " is used)" );
         System.out.println();
-        System.out.println( "Note. GSDI algorithm is under development." );
+        System.out.println( "Example: gsdi -" + ALLOW_STRIPPING_OF_GENE_TREE_OPTION
+                + " gene_tree.xml tree_of_life.xml out.xml" );
         System.out.println();
     }
+
+    private static void printMappedNodesToLog( final EasyWriter log_writer, final GSDII gsdi ) throws IOException {
+        final SortedSet<String> ss = new TreeSet<String>();
+        for( final PhylogenyNode n : gsdi.getMappedExternalSpeciesTreeNodes() ) {
+            ss.add( n.toString() );
+        }
+        log_writer.println( "The following " + ss.size() + " species were used: " );
+        for( final String s : ss ) {
+            log_writer.println( "  " + s );
+        }
+    }
+
+    private static void printStrippedGeneTreeNodesToLog( final EasyWriter log_writer, final GSDII gsdi )
+            throws IOException {
+        final SortedMap<String, Integer> sm = new TreeMap<String, Integer>();
+        for( final PhylogenyNode n : gsdi.getStrippedExternalGeneTreeNodes() ) {
+            final String s = n.toString();
+            if ( sm.containsKey( s ) ) {
+                sm.put( s, sm.get( s ) + 1 );
+            }
+            else {
+                sm.put( s, 1 );
+            }
+        }
+        log_writer.println( "The following " + sm.size() + " nodes were stripped from the gene tree: " );
+        for( final String s : sm.keySet() ) {
+            final int count = sm.get( s );
+            if ( count == 1 ) {
+                log_writer.println( "  " + s );
+            }
+            else {
+                log_writer.println( "  " + s + " [" + count + "]" );
+            }
+        }
+    }
+
+    private static void writeToRemappedFile( final File out_file,
+                                             final SortedSet<String> remapped,
+                                             final EasyWriter log_writer ) throws IOException {
+        final File file = new File( ForesterUtil.removeSuffix( out_file.toString() ) + REMAPPED_SUFFIX );
+        final EasyWriter remapped_writer = ForesterUtil.createEasyWriter( file );
+        for( final String s : remapped ) {
+            remapped_writer.println( s );
+        }
+        remapped_writer.close();
+        System.out.println( "Wrote remapped gene tree species to      : " + file.getCanonicalPath() );
+        log_writer.println( "Wrote remapped gene tree species to      : " + file.getCanonicalPath() );
+    }
 }