JAL-2797 the big switch, all GUI method calls now go via the AptxFrame
[jalview.git] / forester / java / src / org / forester / archaeopteryx / MainFrame.java
index 8079b12..3cdbca2 100644 (file)
@@ -30,18 +30,22 @@ import java.awt.Container;
 import java.awt.Font;
 import java.awt.event.ActionEvent;
 import java.awt.event.ActionListener;
+import java.awt.event.ComponentAdapter;
+import java.awt.event.ComponentListener;
+import java.io.File;
 import java.io.IOException;
+import java.util.ArrayList;
 import java.util.LinkedList;
 import java.util.List;
 import java.util.Locale;
 import java.util.Map;
 import java.util.NoSuchElementException;
-import java.util.Set;
 
 import javax.swing.Box;
-import javax.swing.JApplet;
 import javax.swing.JCheckBoxMenuItem;
+import javax.swing.JFileChooser;
 import javax.swing.JFrame;
+import javax.swing.JInternalFrame;
 import javax.swing.JLabel;
 import javax.swing.JMenu;
 import javax.swing.JMenuBar;
@@ -51,211 +55,369 @@ import javax.swing.JPanel;
 import javax.swing.JRadioButtonMenuItem;
 import javax.swing.JTextField;
 import javax.swing.SwingUtilities;
+import javax.swing.filechooser.FileFilter;
 
+import org.forester.archaeopteryx.AptxUtil.GraphicsExportType;
 import org.forester.archaeopteryx.Options.CLADOGRAM_TYPE;
 import org.forester.archaeopteryx.Options.NODE_LABEL_DIRECTION;
 import org.forester.archaeopteryx.Options.PHYLOGENY_GRAPHICS_TYPE;
+import org.forester.archaeopteryx.tools.AncestralTaxonomyInferrer;
 import org.forester.archaeopteryx.tools.InferenceManager;
 import org.forester.archaeopteryx.tools.ProcessPool;
 import org.forester.archaeopteryx.tools.ProcessRunning;
 import org.forester.io.parsers.nhx.NHXParser.TAXONOMY_EXTRACTION;
+import org.forester.io.writers.PhylogenyWriter;
 import org.forester.phylogeny.Phylogeny;
+import org.forester.phylogeny.PhylogenyMethods;
+import org.forester.phylogeny.PhylogenyMethods.DESCENDANT_SORT_PRIORITY;
 import org.forester.phylogeny.PhylogenyNode;
 import org.forester.phylogeny.PhylogenyNode.NH_CONVERSION_SUPPORT_VALUE_STYLE;
 import org.forester.phylogeny.data.Annotation;
-import org.forester.phylogeny.data.NodeVisualization.NodeFill;
-import org.forester.phylogeny.data.NodeVisualization.NodeShape;
+import org.forester.phylogeny.data.NodeDataField;
+import org.forester.phylogeny.data.NodeVisualData.NodeFill;
+import org.forester.phylogeny.data.NodeVisualData.NodeShape;
+import org.forester.phylogeny.iterators.PhylogenyNodeIterator;
+import org.forester.sdi.GSDI;
+import org.forester.sdi.GSDIR;
+import org.forester.sdi.SDIException;
 import org.forester.util.ForesterConstants;
 import org.forester.util.ForesterUtil;
-
-public abstract class MainFrame extends JFrame implements ActionListener {
-
-    static final String         USE_MOUSEWHEEL_SHIFT_TO_ROTATE          = "In this display type, use mousewheel + Shift to rotate [or A and S]";
-    static final String         PHYLOXML_REF_TOOL_TIP                   = Constants.PHYLOXML_REFERENCE;                                                                                                                                       //TODO //FIXME
-    static final String         APTX_REF_TOOL_TIP                       = Constants.APTX_REFERENCE;
-    private static final long   serialVersionUID                        = 3655000897845508358L;
-    final static Font           menu_font                               = new Font( Configuration.getDefaultFontFamilyName(),
-                                                                                    Font.PLAIN,
-                                                                                    10 );
-    static final String         TYPE_MENU_HEADER                        = "Type";
-    static final String         RECTANGULAR_TYPE_CBMI_LABEL             = "Rectangular";
-    static final String         EURO_TYPE_CBMI_LABEL                    = "Euro Type";
-    static final String         CURVED_TYPE_CBMI_LABEL                  = "Curved";
-    static final String         TRIANGULAR_TYPE_CBMI_LABEL              = "Triangular";
-    static final String         CONVEX_TYPE_CBMI_LABEL                  = "Convex";
-    static final String         ROUNDED_TYPE_CBMI_LABEL                 = "Rounded";
-    static final String         UNROOTED_TYPE_CBMI_LABEL                = "Unrooted (alpha)";                                                                                                                                                 //TODO
-    static final String         CIRCULAR_TYPE_CBMI_LABEL                = "Circular (alpha)";                                                                                                                                                 //TODO
-    static final String         OPTIONS_HEADER                          = "Options";
-    static final String         SEARCH_SUBHEADER                        = "Search:";
-    static final String         DISPLAY_SUBHEADER                       = "Display:";
-    static final String         SEARCH_TERMS_ONLY_LABEL                 = "Match Complete Terms Only";
-    static final String         SEARCH_CASE_SENSITIVE_LABEL             = "Case Sensitive";
-    static final String         INVERSE_SEARCH_RESULT_LABEL             = "Negate Result";
-    static final String         DISPLAY_BRANCH_LENGTH_VALUES_LABEL      = "Display Branch Length Values";
-    static final String         DISPLAY_SCALE_LABEL                     = "Display Scale";
-    static final String         NON_LINED_UP_CLADOGRAMS_LABEL           = "Non-Lined Up Cladograms";
-    static final String         UNIFORM_CLADOGRAMS_LABEL                = "Total Node Sum Dependent Cladograms";
-    static final String         LABEL_DIRECTION_LABEL                   = "Radial Labels";
-    static final String         LABEL_DIRECTION_TIP                     = "To use radial node labels in radial and unrooted display types";
-    static final String         SCREEN_ANTIALIAS_LABEL                  = "Antialias";
-    static final String         COLOR_LABELS_LABEL                      = "Colorize Labels Same as Parent Branch";
-    static final String         BG_GRAD_LABEL                           = "Background Color Gradient";
-    static final String         DISPLAY_NODE_BOXES_LABEL_EXT            = "Show External Node Shapes";
-    static final String         DISPLAY_NODE_BOXES_LABEL_INT            = "Show Internal Node Shapes";
-    static final String         SHOW_OVERVIEW_LABEL                     = "Show Overview";
-    static final String         FONT_SIZE_MENU_LABEL                    = "Font Size";
-    static final String         NONUNIFORM_CLADOGRAMS_LABEL             = "External Node Sum Dependent Cladograms";
-    static final String         SHOW_DOMAIN_LABELS_LABEL                = "Show Domain Labels";
-    static final String         COLOR_LABELS_TIP                        = "To use parent branch colors for node labels as well, need to turn off taxonomy dependent colorization and turn on branch colorization for this to become apparent";
-    static final String         ABBREV_SN_LABEL                         = "Abbreviate Scientific Taxonomic Names";
-    static final String         TAXONOMY_COLORIZE_NODE_SHAPES_LABEL     = "Colorize Node Shapes According to Taxonomy";
-    static final String         CYCLE_NODE_SHAPE_LABEL                  = "Cycle Node Shapes";
-    static final String         CYCLE_NODE_FILL_LABEL                   = "Cycle Node Fill Type";
-    static final String         CHOOSE_NODE_SIZE_LABEL                  = "Choose Node Shape Size";
-    static final String         SHOW_CONF_STDDEV_LABEL                  = "Show Confidence Standard Deviations";
-    static final String         USE_BRACKETS_FOR_CONF_IN_NH_LABEL       = "Use Brackets for Confidence Values";
-    static final String         USE_INTERNAL_NAMES_FOR_CONF_IN_NH_LABEL = "Use Internal Node Names for Confidence Values";
-    JMenuBar                    _jmenubar;
-    JMenu                       _file_jmenu;
-    JMenu                       _tools_menu;
-    JMenu                       _view_jmenu;
-    JMenu                       _options_jmenu;
-    JMenu                       _font_size_menu;
-    JMenu                       _help_jmenu;
-    JMenuItem[]                 _load_phylogeny_from_webservice_menu_items;
+import org.forester.util.WindowsUtils;
+
+public abstract class MainFrame implements ActionListener {
+
+    public final static NHFilter            nhfilter                                = new NHFilter();
+    public final static NHXFilter           nhxfilter                               = new NHXFilter();
+    public final static XMLFilter           xmlfilter                               = new XMLFilter();
+    public final static TolFilter           tolfilter                               = new TolFilter();
+    public final static NexusFilter         nexusfilter                             = new NexusFilter();
+    public final static PdfFilter           pdffilter                               = new PdfFilter();
+    public final static GraphicsFileFilter  graphicsfilefilter                      = new GraphicsFileFilter();
+    public final static MsaFileFilter       msafilter                               = new MsaFileFilter();
+    public final static SequencesFileFilter seqsfilter                              = new SequencesFileFilter();
+    public final static DefaultFilter       defaultfilter                           = new DefaultFilter();
+    static final String              USE_MOUSEWHEEL_SHIFT_TO_ROTATE          = "rotate with mousewheel + Shift (or A and S), D toggles between horizontal and radial labels";
+    static final String              PHYLOXML_REF_TOOL_TIP                   = AptxConstants.PHYLOXML_REFERENCE;                                                                                                                                                //TODO //FIXME
+    static final String              APTX_REF_TOOL_TIP                       = AptxConstants.APTX_REFERENCE;
+    private static final long        serialVersionUID                        = 3655000897845508358L;
+    final static Font                menu_font                               = new Font( Configuration.getDefaultFontFamilyName(),
+                                                                                         Font.PLAIN,
+                                                                                         10 );
+    static final String              TYPE_MENU_HEADER                        = "Type";
+    static final String              RECTANGULAR_TYPE_CBMI_LABEL             = "Rectangular";
+    static final String              EURO_TYPE_CBMI_LABEL                    = "Euro Type";
+    static final String              CURVED_TYPE_CBMI_LABEL                  = "Curved";
+    static final String              TRIANGULAR_TYPE_CBMI_LABEL              = "Triangular";
+    static final String              CONVEX_TYPE_CBMI_LABEL                  = "Convex";
+    static final String              ROUNDED_TYPE_CBMI_LABEL                 = "Rounded";
+    static final String              UNROOTED_TYPE_CBMI_LABEL                = "Unrooted (alpha)";                                                                                                                                                          //TODO
+    static final String              CIRCULAR_TYPE_CBMI_LABEL                = "Circular (alpha)";                                                                                                                                                          //TODO
+    static final String              OPTIONS_HEADER                          = "Options";
+    static final String              SEARCH_SUBHEADER                        = "Search:";
+    static final String              DISPLAY_SUBHEADER                       = "Display:";
+    static final String              SEARCH_TERMS_ONLY_LABEL                 = "Words";
+    static final String              SEARCH_REGEX_LABEL                      = "Regex";
+    static final String              SEARCH_CASE_SENSITIVE_LABEL             = "Match Case";
+    static final String              INVERSE_SEARCH_RESULT_LABEL             = "Inverse";
+    static final String              COLOR_BY_TAXONOMIC_GROUP                = "Colorize by Taxonomic Group";
+    static final String              DISPLAY_SCALE_LABEL                     = "Scale";
+    static final String              NON_LINED_UP_CLADOGRAMS_LABEL           = "Non-Lined Up Cladogram";
+    static final String              LABEL_DIRECTION_LABEL                   = "Radial Labels";
+    static final String              LABEL_DIRECTION_TIP                     = "To use radial node labels in radial and unrooted display types";
+    static final String              SEARCH_WITH_REGEX_TIP                   = "To search using regular expressions (~Java/Perl syntax). For example, use \"^B.+\\d{2,}$\" to search for everything starting with a B and ending with at least two digits.";
+    static final String              SCREEN_ANTIALIAS_LABEL                  = "Antialias";
+    static final String              COLOR_LABELS_LABEL                      = "Colorize Labels Same as Parent Branch";
+    static final String              BG_GRAD_LABEL                           = "Background Color Gradient";
+    static final String              DISPLAY_NODE_BOXES_LABEL_EXT            = "Shapes for External Nodes";
+    static final String              DISPLAY_NODE_BOXES_LABEL_INT            = "Shapes for Internal Nodes";
+    static final String              DISPLAY_NODE_BOXES_LABEL_MARKED         = "Shapes for Nodes with Visual Data";
+    static final String              SHOW_OVERVIEW_LABEL                     = "Overview";
+    static final String              FONT_SIZE_MENU_LABEL                    = "Font Size";
+    static final String              NONUNIFORM_CLADOGRAMS_LABEL             = "Lined Up Cladogram";
+    static final String              SHOW_DOMAIN_LABELS_LABEL                = "Domain Labels";
+    static final String              SHOW_ANN_REF_SOURCE_LABEL               = "Seq Annotation Ref Sources";
+    static final String              COLOR_LABELS_TIP                        = "To use parent branch colors for node labels as well, need to turn off taxonomy dependent colorization and turn on branch colorization for this to become apparent";
+    static final String              ABBREV_SN_LABEL                         = "Abbreviate Scientific Taxonomic Names";
+    static final String              TAXONOMY_COLORIZE_NODE_SHAPES_LABEL     = "Colorize Node Shapes According to Taxonomy";
+    static final String              CYCLE_NODE_SHAPE_LABEL                  = "Cycle Node Shapes";
+    static final String              CYCLE_NODE_FILL_LABEL                   = "Cycle Node Fill Type";
+    static final String              CHOOSE_NODE_SIZE_LABEL                  = "Choose Node Shape Size";
+    static final String              SHOW_CONF_STDDEV_LABEL                  = "Confidence Standard Deviations";
+    static final String              USE_BRACKETS_FOR_CONF_IN_NH_LABEL       = "Use Brackets for Confidence Values";
+    static final String              USE_INTERNAL_NAMES_FOR_CONF_IN_NH_LABEL = "Use Internal Node Names for Confidence Values";
+    static final String              SHOW_BASIC_TREE_INFORMATION_LABEL       = "Basic Tree Information";
+    static final String              RIGHT_LINE_UP_DOMAINS                   = "Right-align Domain Architectures";
+    static final String              LINE_UP_RENDERABLE_DATA                 = "Line Up Diagrams (such as Domain Architectures)";
+    static final String              INFER_ANCESTOR_TAXONOMIES               = "Infer Ancestor Taxonomies";
+    static final String              OBTAIN_DETAILED_TAXONOMIC_INFORMATION   = "Obtain Detailed Taxonomic Information";
+    
+    final AptxFrame                  _frame;
+    JMenuBar                         _jmenubar;
+    JMenu                            _file_jmenu;
+    JMenu                            _tools_menu;
+    JMenu                            _view_jmenu;
+    JMenu                            _options_jmenu;
+    JMenu                            _font_size_menu;
+    JMenu                            _help_jmenu;
+    JMenuItem[]                      _load_phylogeny_from_webservice_menu_items;
+    // Analysis menu
+    JMenu                            _analysis_menu;
+    JMenuItem                        _load_species_tree_item;
+    JMenuItem                        _gsdi_item;
+    JMenuItem                        _gsdir_item;
+    JMenuItem                        _lineage_inference;
     // file menu:
-    JMenuItem                   _open_item;
-    JMenuItem                   _open_url_item;
-    JMenuItem                   _save_item;
-    JMenuItem                   _save_all_item;
-    JMenuItem                   _close_item;
-    JMenuItem                   _exit_item;
-    JMenuItem                   _new_item;
+    JMenuItem                        _open_item;
+    JMenuItem                        _open_url_item;
+    JMenuItem                        _save_item;
+    JMenuItem                        _save_all_item;
+    JMenuItem                        _close_item;
+    JMenuItem                        _exit_item;
+    JMenuItem                        _new_item;
+    JMenuItem                        _print_item;
+    JMenuItem                        _write_to_pdf_item;
+    JMenuItem                        _write_to_jpg_item;
+    JMenuItem                        _write_to_gif_item;
+    JMenuItem                        _write_to_tif_item;
+    JMenuItem                        _write_to_png_item;
+    JMenuItem                        _write_to_bmp_item;
     // tools menu:
-    JMenuItem                   _midpoint_root_item;
-    JMenuItem                   _taxcolor_item;
-    JMenuItem                   _confcolor_item;
-    JMenuItem                   _color_rank_jmi;
-    JMenuItem                   _collapse_species_specific_subtrees;
-    JMenuItem                   _collapse_below_threshold;                                                                                                                                                                                    //TODO implememt me
-    JMenuItem                   _obtain_detailed_taxonomic_information_jmi;
-    JMenuItem                   _obtain_detailed_taxonomic_information_deleting_jmi;
-    JMenuItem                   _obtain_seq_information_jmi;
-    JMenuItem                   _move_node_names_to_tax_sn_jmi;
-    JMenuItem                   _move_node_names_to_seq_names_jmi;
-    JMenuItem                   _extract_tax_code_from_node_names_jmi;
-    JMenuItem                   _annotate_item;
+    JMenuItem                        _midpoint_root_item;
+    JMenuItem                        _taxcolor_item;
+    JMenuItem                        _confcolor_item;
+    JMenuItem                        _color_rank_jmi;
+    JMenuItem                        _collapse_species_specific_subtrees;
+    
+    JMenuItem                        _obtain_detailed_taxonomic_information_jmi;
+    JMenuItem                        _obtain_detailed_taxonomic_information_deleting_jmi;
+    JMenuItem                        _obtain_seq_information_jmi;
+    JMenuItem                        _move_node_names_to_tax_sn_jmi;
+    JMenuItem                        _move_node_names_to_seq_names_jmi;
+    JMenuItem                        _extract_tax_code_from_node_names_jmi;
+    JMenuItem                        _annotate_item;
+    JMenuItem                        _remove_branch_color_item;
+    JMenuItem                        _remove_visual_styles_item;
+    JMenuItem                        _delete_selected_nodes_item;
+    JMenuItem                        _delete_not_selected_nodes_item;
     // font size menu:
-    JMenuItem                   _super_tiny_fonts_item;
-    JMenuItem                   _tiny_fonts_item;
-    JMenuItem                   _small_fonts_item;
-    JMenuItem                   _medium_fonts_item;
-    JMenuItem                   _large_fonts_item;
+    JMenuItem                        _super_tiny_fonts_item;
+    JMenuItem                        _tiny_fonts_item;
+    JMenuItem                        _small_fonts_item;
+    JMenuItem                        _medium_fonts_item;
+    JMenuItem                        _large_fonts_item;
     // options menu:
     // _  screen and print
-    JMenuItem                   _choose_font_mi;
-    JMenuItem                   _switch_colors_mi;
-    JCheckBoxMenuItem           _label_direction_cbmi;
+    JMenuItem                        _choose_font_mi;
+    JMenuItem                        _switch_colors_mi;
+    JCheckBoxMenuItem                _label_direction_cbmi;
     // _  screen display
-    JCheckBoxMenuItem           _screen_antialias_cbmi;
-    JCheckBoxMenuItem           _background_gradient_cbmi;
-    JRadioButtonMenuItem        _non_lined_up_cladograms_rbmi;
-    JRadioButtonMenuItem        _uniform_cladograms_rbmi;
-    JRadioButtonMenuItem        _ext_node_dependent_cladogram_rbmi;
-    JCheckBoxMenuItem           _show_branch_length_values_cbmi;
-    JCheckBoxMenuItem           _show_scale_cbmi;                                                                                                                                                                                             //TODO fix me
-    JCheckBoxMenuItem           _show_overview_cbmi;
-    JCheckBoxMenuItem           _show_domain_labels;
-    JCheckBoxMenuItem           _abbreviate_scientific_names;
-    JCheckBoxMenuItem           _color_labels_same_as_parent_branch;
-    JMenuItem                   _overview_placment_mi;
-    JMenuItem                   _choose_minimal_confidence_mi;
-    JCheckBoxMenuItem           _show_default_node_shapes_internal_cbmi;
-    JCheckBoxMenuItem           _show_default_node_shapes_external_cbmi;
-    JMenuItem                   _cycle_node_shape_mi;
-    JMenuItem                   _cycle_node_fill_mi;
-    JMenuItem                   _choose_node_size_mi;
-    JCheckBoxMenuItem           _taxonomy_colorize_node_shapes_cbmi;
-    JCheckBoxMenuItem           _show_confidence_stddev_cbmi;
+    JCheckBoxMenuItem                _screen_antialias_cbmi;
+    JCheckBoxMenuItem                _background_gradient_cbmi;
+    JRadioButtonMenuItem             _non_lined_up_cladograms_rbmi;
+    JRadioButtonMenuItem             _ext_node_dependent_cladogram_rbmi;
+    JCheckBoxMenuItem                _color_by_taxonomic_group_cbmi;
+    JCheckBoxMenuItem                _show_scale_cbmi;                                                                                                                                                                                                      //TODO fix me
+    JCheckBoxMenuItem                _show_overview_cbmi;
+    JCheckBoxMenuItem                _show_domain_labels;
+    JCheckBoxMenuItem                _show_annotation_ref_source;
+    JCheckBoxMenuItem                _abbreviate_scientific_names;
+    JCheckBoxMenuItem                _color_labels_same_as_parent_branch;
+    JMenuItem                        _overview_placment_mi;
+    JMenuItem                        _choose_minimal_confidence_mi;
+    JCheckBoxMenuItem                _show_default_node_shapes_internal_cbmi;
+    JCheckBoxMenuItem                _show_default_node_shapes_external_cbmi;
+    JCheckBoxMenuItem                _show_default_node_shapes_for_marked_cbmi;
+    JMenuItem                        _cycle_node_shape_mi;
+    JMenuItem                        _cycle_node_fill_mi;
+    JMenuItem                        _choose_node_size_mi;
+    JMenuItem                        _cycle_data_return;
+    JCheckBoxMenuItem                _show_confidence_stddev_cbmi;
+    JCheckBoxMenuItem                _right_line_up_domains_cbmi;
+    JCheckBoxMenuItem                _line_up_renderable_data_cbmi;
+    JCheckBoxMenuItem                _collapsed_with_average_height_cbmi;
+    JCheckBoxMenuItem                _show_abbreviated_labels_for_collapsed_nodes_cbmi;
     // _  print
-    JCheckBoxMenuItem           _graphics_export_visible_only_cbmi;
-    JCheckBoxMenuItem           _antialias_print_cbmi;
-    JCheckBoxMenuItem           _print_black_and_white_cbmi;
-    JCheckBoxMenuItem           _print_using_actual_size_cbmi;
-    JCheckBoxMenuItem           _graphics_export_using_actual_size_cbmi;
-    JMenuItem                   _print_size_mi;
-    JMenuItem                   _choose_pdf_width_mi;
+    JCheckBoxMenuItem                _graphics_export_visible_only_cbmi;
+    JCheckBoxMenuItem                _antialias_print_cbmi;
+    JCheckBoxMenuItem                _print_black_and_white_cbmi;
+    //JMenuItem                        _print_size_mi;
+    JMenuItem                        _choose_pdf_width_mi;
     // _  parsing
-    JCheckBoxMenuItem           _internal_number_are_confidence_for_nh_parsing_cbmi;
-    JRadioButtonMenuItem        _extract_taxonomy_no_rbmi;
-    JRadioButtonMenuItem        _extract_taxonomy_yes_rbmi;
-    JRadioButtonMenuItem        _extract_taxonomy_pfam_rbmi;
-    JCheckBoxMenuItem           _replace_underscores_cbmi;
-    JCheckBoxMenuItem           _use_brackets_for_conf_in_nh_export_cbmi;
-    JCheckBoxMenuItem           _use_internal_names_for_conf_in_nh_export_cbmi;
+    JCheckBoxMenuItem                _internal_number_are_confidence_for_nh_parsing_cbmi;
+    JRadioButtonMenuItem             _extract_taxonomy_no_rbmi;
+    JRadioButtonMenuItem             _extract_taxonomy_agressive_rbmi;
+    JRadioButtonMenuItem             _extract_taxonomy_pfam_strict_rbmi;
+    JRadioButtonMenuItem             _extract_taxonomy_pfam_relaxed_rbmi;
+    JCheckBoxMenuItem                _replace_underscores_cbmi;
+    JCheckBoxMenuItem                _allow_errors_in_distance_to_parent_cbmi;
+    JCheckBoxMenuItem                _use_brackets_for_conf_in_nh_export_cbmi;
+    JCheckBoxMenuItem                _use_internal_names_for_conf_in_nh_export_cbmi;
+    JCheckBoxMenuItem                _parse_beast_style_extended_nexus_tags_cbmi;
     // _  search
-    JCheckBoxMenuItem           _search_case_senstive_cbmi;
-    JCheckBoxMenuItem           _search_whole_words_only_cbmi;
-    JCheckBoxMenuItem           _inverse_search_result_cbmi;
+    JCheckBoxMenuItem                _search_case_senstive_cbmi;
+    JCheckBoxMenuItem                _search_whole_words_only_cbmi;
+    JCheckBoxMenuItem                _inverse_search_result_cbmi;
+    JCheckBoxMenuItem                _search_with_regex_cbmi;
+    JCheckBoxMenuItem                _color_all_found_nodes_when_coloring_subtree_cbmi;
     // type menu:
-    JMenu                       _type_menu;
-    JCheckBoxMenuItem           _rectangular_type_cbmi;
-    JCheckBoxMenuItem           _triangular_type_cbmi;
-    JCheckBoxMenuItem           _curved_type_cbmi;
-    JCheckBoxMenuItem           _convex_type_cbmi;
-    JCheckBoxMenuItem           _euro_type_cbmi;
-    JCheckBoxMenuItem           _rounded_type_cbmi;
-    JCheckBoxMenuItem           _unrooted_type_cbmi;
-    JCheckBoxMenuItem           _circular_type_cbmi;
+    JMenu                            _type_menu;
+    JCheckBoxMenuItem                _rectangular_type_cbmi;
+    JCheckBoxMenuItem                _triangular_type_cbmi;
+    JCheckBoxMenuItem                _curved_type_cbmi;
+    JCheckBoxMenuItem                _convex_type_cbmi;
+    JCheckBoxMenuItem                _euro_type_cbmi;
+    JCheckBoxMenuItem                _rounded_type_cbmi;
+    JCheckBoxMenuItem                _unrooted_type_cbmi;
+    JCheckBoxMenuItem                _circular_type_cbmi;
     // view as text menu:
-    JMenuItem                   _view_as_NH_item;
-    JMenuItem                   _view_as_XML_item;
-    JMenuItem                   _view_as_nexus_item;
-    JMenuItem                   _display_basic_information_item;
+    JMenuItem                        _view_as_NH_item;
+    JMenuItem                        _view_as_XML_item;
+    JMenuItem                        _view_as_nexus_item;
+    JMenuItem                        _display_basic_information_item;
     // help menu:
-    JMenuItem                   _about_item;
-    JMenuItem                   _help_item;
-    JMenuItem                   _website_item;
-    JMenuItem                   _phyloxml_website_item;
-    JMenuItem                   _phyloxml_ref_item;
-    JMenuItem                   _aptx_ref_item;
+    JMenuItem                        _about_item;
+    JMenuItem                        _help_item;
+    JMenuItem                        _website_item;
+    JMenuItem                        _aptxjs_website_item;
+    JMenuItem                        _mailing_list_item;
+    JMenuItem                        _phyloxml_website_item;
+    JMenuItem                        _phyloxml_ref_item;
+    JMenuItem                        _aptx_ref_item;
+    //
+    File                             _current_dir;
+    JFileChooser                     _writetopdf_filechooser;
+    JFileChooser                     _save_filechooser;
+    JFileChooser                     _writetographics_filechooser;
     // process menu:
-    JMenu                       _process_menu;
-    // Handy pointers to child components:
-    MainPanel                   _mainpanel;
-    Container                   _contentpane;
-    final LinkedList<TextFrame> _textframes                             = new LinkedList<TextFrame>();                                                                                                                                         ;
-    Configuration               _configuration;
-    JMenuItem                   _remove_branch_color_item;
-    Options                     _options;
-    InferenceManager            _inference_manager;
-    final ProcessPool           _process_pool;
-    private String              _previous_node_annotation_ref;
+    JMenu                            _process_menu;
+    MainPanel                        _mainpanel;
+    Container                        _contentpane;
+    final LinkedList<TextFrame>      _textframes                             = new LinkedList<TextFrame>();                                                                                                                                                  ;
+    Configuration                    _configuration;
+    Options                          _options;
+    private Phylogeny                _species_tree;
+    InferenceManager                 _inference_manager;
+    final ProcessPool                _process_pool;
+    private String                   _previous_node_annotation_ref;
 
     MainFrame() {
+        this(false);
+    }
+    MainFrame(boolean embedded){
+        if (embedded) {
+            _frame = new EmbeddedFrame();
+        }
+        else {
+            _frame = new StandaloneFrame();
+        } 
         _process_pool = ProcessPool.createInstance();
+        _writetopdf_filechooser = new JFileChooser();
+        _writetopdf_filechooser.setMultiSelectionEnabled( false );
+        _writetopdf_filechooser.addChoosableFileFilter( pdffilter );
+        _writetographics_filechooser = new JFileChooser();
+        _writetographics_filechooser.setMultiSelectionEnabled( false );
+        _writetographics_filechooser.addChoosableFileFilter( graphicsfilefilter );
+        _save_filechooser = new JFileChooser();
+        _save_filechooser.setMultiSelectionEnabled( false );
+        _save_filechooser.setFileFilter( xmlfilter );
+        _save_filechooser.addChoosableFileFilter( nhfilter );
+        _save_filechooser.addChoosableFileFilter( nexusfilter );
+        _save_filechooser.addChoosableFileFilter( _save_filechooser.getAcceptAllFileFilter() );
+        try {
+            final String home_dir = System.getProperty( "user.home" );
+            _save_filechooser.setCurrentDirectory( new File( home_dir ) );
+            _writetopdf_filechooser.setCurrentDirectory( new File( home_dir ) );
+            _writetographics_filechooser.setCurrentDirectory( new File( home_dir ) );
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            // Do nothing. Not important.
+        }
     }
-
+    public void addComponentListener( ComponentListener componentListener ) {
+        _frame.addComponentListener( componentListener );
+        
+    }
+    
+    public void dispose() {
+        _frame.dispose();
+    }
+    public Container getContentPane() {
+        return _frame.getContentPane();
+    }
+    
+    public void repaint() {
+       _frame.repaint();
+    }
+    
+     
+    public void addFrameListener(FrameListener frameListener) {
+        _frame.addFrameListener(frameListener);
+    }
+    
+    public void setSize(int x, int y) {
+        _frame.setSize(x,y);
+    }
+    public Container getJMenuBar() {
+        return _frame.getJMenuBar();
+    }
+    public void setDefaultCloseOperation( int doNothingOnClose ) {
+        _frame.setDefaultCloseOperation(doNothingOnClose);
+        
+    }
+    public Container getParent() {
+        return _frame.getParent();
+    }
+    public void setVisible(boolean visible) {
+        _frame.setVisible(visible);
+    }
+    public void requestFocusInWindow() {
+        _frame.requestFocusInWindow();
+    }
+    public void setJMenuBar( JMenuBar jmenubar ) {
+        _frame.setJMenuBar(jmenubar);
+    }
+    public void setLocationRelativeTo( Component component ) {
+        _frame.setLocationRelativeTo(component);  
+    }
+    public void setTitle(String title) {
+       _frame.setTitle(title);
+    }
+    
+    public Container getThisFrame() {
+        return _frame.getThisFrame();
+    }
+    
+    public void validate() {
+        _frame.validate();
+    }
+    
+    
+    
+    
+    
+    
     /**
      * Action performed.
      */
     @Override
     public void actionPerformed( final ActionEvent e ) {
         final Object o = e.getSource();
-        boolean is_applet = false;
-        JApplet applet = null;
-        if ( getCurrentTreePanel() != null ) {
-            is_applet = getCurrentTreePanel().isApplet();
-            if ( is_applet ) {
-                applet = getCurrentTreePanel().obtainApplet();
-            }
+      
+        if ( o == _exit_item ) {
+            close();
         }
-        if ( o == _open_url_item ) {
-            readPhylogeniesFromURL();
+        else if ( o == _gsdi_item ) {
+            if ( isSubtreeDisplayed() ) {
+                return;
+            }
+            executeGSDI();
         }
-        else if ( o == _exit_item ) {
-            close();
+        else if ( o == _gsdir_item ) {
+            if ( isSubtreeDisplayed() ) {
+                return;
+            }
+            executeGSDIR();
         }
         else if ( o == _taxcolor_item ) {
             taxColor();
@@ -280,12 +442,30 @@ public abstract class MainFrame extends JFrame implements ActionListener {
             }
             removeBranchColors();
         }
+        else if ( o == _remove_visual_styles_item ) {
+            if ( isSubtreeDisplayed() ) {
+                return;
+            }
+            removeVisualStyles();
+        }
         else if ( o == _midpoint_root_item ) {
             if ( isSubtreeDisplayed() ) {
                 return;
             }
             midpointRoot();
         }
+        else if ( o == _delete_selected_nodes_item ) {
+            if ( isSubtreeDisplayed() ) {
+                return;
+            }
+            deleteSelectedNodes( true );
+        }
+        else if ( o == _delete_not_selected_nodes_item ) {
+            if ( isSubtreeDisplayed() ) {
+                return;
+            }
+            deleteSelectedNodes( false );
+        }
         else if ( o == _annotate_item ) {
             annotateSequences();
         }
@@ -293,7 +473,9 @@ public abstract class MainFrame extends JFrame implements ActionListener {
             switchColors();
         }
         else if ( o == _display_basic_information_item ) {
-            displayBasicInformation();
+            if ( getCurrentTreePanel() != null ) {
+                displayBasicInformation( getCurrentTreePanel().getTreeFile() );
+            }
         }
         else if ( o == _view_as_NH_item ) {
             viewAsNH();
@@ -341,16 +523,19 @@ public abstract class MainFrame extends JFrame implements ActionListener {
             chooseMinimalConfidence();
         }
         else if ( o == _choose_node_size_mi ) {
-            chooseNodeSize( getOptions(), this );
+            chooseNodeSize( getOptions(), _frame.getThisFrame() );
         }
         else if ( o == _overview_placment_mi ) {
             MainFrame.cycleOverview( getOptions(), getCurrentTreePanel() );
         }
         else if ( o == _cycle_node_fill_mi ) {
-            MainFrame.cycleNodeFill( getOptions(), getCurrentTreePanel() );
+            MainFrame.cycleNodeFill( getOptions() );
         }
         else if ( o == _cycle_node_shape_mi ) {
-            MainFrame.cycleNodeShape( getOptions(), getCurrentTreePanel() );
+            MainFrame.cycleNodeShape( getOptions() );
+        }
+        else if ( o == _cycle_data_return ) {
+            MainFrame.cycleNodeDataReturn( getOptions(), getConfiguration() );
         }
         else if ( o == _screen_antialias_cbmi ) {
             updateOptions( getOptions() );
@@ -362,6 +547,9 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         else if ( o == _show_domain_labels ) {
             updateOptions( getOptions() );
         }
+        else if ( o == _show_annotation_ref_source ) {
+            updateOptions( getOptions() );
+        }
         else if ( o == _abbreviate_scientific_names ) {
             updateOptions( getOptions() );
         }
@@ -374,37 +562,59 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         else if ( o == _show_default_node_shapes_external_cbmi ) {
             updateOptions( getOptions() );
         }
-        else if ( o == _taxonomy_colorize_node_shapes_cbmi ) {
+        else if ( o == _show_default_node_shapes_for_marked_cbmi ) {
             updateOptions( getOptions() );
         }
         else if ( o == _non_lined_up_cladograms_rbmi ) {
             updateOptions( getOptions() );
             showWhole();
         }
-        else if ( o == _uniform_cladograms_rbmi ) {
-            updateOptions( getOptions() );
-            showWhole();
-        }
         else if ( o == _ext_node_dependent_cladogram_rbmi ) {
             updateOptions( getOptions() );
             showWhole();
         }
         else if ( o == _search_case_senstive_cbmi ) {
+            if ( ( _search_with_regex_cbmi != null ) && _search_case_senstive_cbmi.isSelected() ) {
+                _search_with_regex_cbmi.setSelected( false );
+            }
             updateOptions( getOptions() );
-            getMainPanel().getControlPanel().search();
+            getMainPanel().getControlPanel().search0();
+            getMainPanel().getControlPanel().search1();
         }
         else if ( o == _search_whole_words_only_cbmi ) {
+            if ( ( _search_with_regex_cbmi != null ) && _search_whole_words_only_cbmi.isSelected() ) {
+                _search_with_regex_cbmi.setSelected( false );
+            }
             updateOptions( getOptions() );
-            getMainPanel().getControlPanel().search();
+            getMainPanel().getControlPanel().search0();
+            getMainPanel().getControlPanel().search1();
         }
         else if ( o == _inverse_search_result_cbmi ) {
             updateOptions( getOptions() );
-            getMainPanel().getControlPanel().search();
+            getMainPanel().getControlPanel().search0();
+            getMainPanel().getControlPanel().search1();
+        }
+        else if ( o == _search_with_regex_cbmi ) {
+            if ( ( _search_whole_words_only_cbmi != null ) && _search_with_regex_cbmi.isSelected() ) {
+                _search_whole_words_only_cbmi.setSelected( false );
+            }
+            if ( ( _search_case_senstive_cbmi != null ) && _search_with_regex_cbmi.isSelected() ) {
+                _search_case_senstive_cbmi.setSelected( false );
+            }
+            updateOptions( getOptions() );
+            getMainPanel().getControlPanel().search0();
+            getMainPanel().getControlPanel().search1();
+        }
+        else if ( o == _color_all_found_nodes_when_coloring_subtree_cbmi ) {
+            updateOptions( getOptions() );
+        }
+        else if ( o == _parse_beast_style_extended_nexus_tags_cbmi ) {
+            updateOptions( getOptions() );
         }
         else if ( o == _show_scale_cbmi ) {
             updateOptions( getOptions() );
         }
-        else if ( o == _show_branch_length_values_cbmi ) {
+        else if ( o == _color_by_taxonomic_group_cbmi ) {
             updateOptions( getOptions() );
         }
         else if ( o == _show_confidence_stddev_cbmi ) {
@@ -431,6 +641,31 @@ public abstract class MainFrame extends JFrame implements ActionListener {
                 getCurrentTreePanel().updateOvSizes();
             }
         }
+        else if ( o == _line_up_renderable_data_cbmi ) {
+            if ( !_line_up_renderable_data_cbmi.isSelected() ) {
+                _right_line_up_domains_cbmi.setSelected( false );
+            }
+            updateOptions( getOptions() );
+        }
+        
+        else if ( o == _collapsed_with_average_height_cbmi ) {
+            if ( _collapsed_with_average_height_cbmi.isSelected() ) {
+                _collapsed_with_average_height_cbmi.setSelected( true );
+            }
+            updateOptions( getOptions() );
+        }
+        else if ( o == _show_abbreviated_labels_for_collapsed_nodes_cbmi ) {
+            if ( _show_abbreviated_labels_for_collapsed_nodes_cbmi.isSelected() ) {
+                _show_abbreviated_labels_for_collapsed_nodes_cbmi.setSelected( true );
+            }
+            updateOptions( getOptions() );
+        }
+        else if ( o == _right_line_up_domains_cbmi ) {
+            if ( _right_line_up_domains_cbmi.isSelected() ) {
+                _line_up_renderable_data_cbmi.setSelected( true );
+            }
+            updateOptions( getOptions() );
+        }
         else if ( ( o == _rectangular_type_cbmi ) || ( o == _triangular_type_cbmi ) || ( o == _curved_type_cbmi )
                 || ( o == _convex_type_cbmi ) || ( o == _euro_type_cbmi ) || ( o == _rounded_type_cbmi )
                 || ( o == _unrooted_type_cbmi ) || ( o == _circular_type_cbmi ) ) {
@@ -440,40 +675,171 @@ public abstract class MainFrame extends JFrame implements ActionListener {
             about();
         }
         else if ( o == _help_item ) {
-            help( getConfiguration().getWebLinks() );
+            try {
+                AptxUtil.openWebsite( AptxConstants.APTX_DOC_SITE );
+            }
+            catch ( final IOException e1 ) {
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
+            }
         }
         else if ( o == _website_item ) {
             try {
-                AptxUtil.openWebsite( Constants.APTX_WEB_SITE, is_applet, applet );
+                AptxUtil.openWebsite( AptxConstants.APTX_WEB_SITE);
             }
             catch ( final IOException e1 ) {
-                ForesterUtil.printErrorMessage( Constants.PRG_NAME, e1.toString() );
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
+            }
+        }
+        else if ( o == _aptxjs_website_item ) {
+            try {
+                AptxUtil.openWebsite( AptxConstants.APTX_JS_WEB_SITE);;
+            }
+            catch ( final IOException e1 ) {
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
+            }
+        }
+        else if ( o == _mailing_list_item ) {
+            try {
+                AptxUtil.openWebsite( AptxConstants.APTX_MAILING_LIST );
+            }
+            catch ( final IOException e1 ) {
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
             }
         }
         else if ( o == _phyloxml_website_item ) {
             try {
-                AptxUtil.openWebsite( Constants.PHYLOXML_WEB_SITE, is_applet, applet );
+                AptxUtil.openWebsite( AptxConstants.PHYLOXML_WEB_SITE );
             }
             catch ( final IOException e1 ) {
-                ForesterUtil.printErrorMessage( Constants.PRG_NAME, e1.toString() );
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
             }
         }
         else if ( o == _aptx_ref_item ) {
             try {
-                AptxUtil.openWebsite( Constants.APTX_REFERENCE_URL, is_applet, applet );
+                AptxUtil.openWebsite( AptxConstants.APTX_REFERENCE_URL );
             }
             catch ( final IOException e1 ) {
-                ForesterUtil.printErrorMessage( Constants.PRG_NAME, e1.toString() );
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
             }
         }
         else if ( o == _phyloxml_ref_item ) {
             try {
-                AptxUtil.openWebsite( Constants.PHYLOXML_REFERENCE_URL, is_applet, applet );
+                AptxUtil.openWebsite( AptxConstants.PHYLOXML_REFERENCE_URL );
             }
             catch ( final IOException e1 ) {
-                ForesterUtil.printErrorMessage( Constants.PRG_NAME, e1.toString() );
+                ForesterUtil.printErrorMessage( AptxConstants.PRG_NAME, e1.toString() );
+            }
+        }
+        else if ( o == _write_to_pdf_item ) {
+            final File curr_dir = writeToPdf( _mainpanel.getCurrentPhylogeny(),
+                                              getMainPanel(),
+                                              _writetopdf_filechooser,
+                                              _current_dir,
+                                              getContentPane(),
+                                              getThisFrame() );
+            if ( curr_dir != null ) {
+                setCurrentDir( curr_dir );
+            }
+        }
+        else if ( o == _save_all_item ) {
+            writeAllToFile();
+        }
+        else if ( o == _write_to_jpg_item ) {
+            final File new_dir = writeToGraphicsFile( _mainpanel.getCurrentPhylogeny(),
+                                                      GraphicsExportType.JPG,
+                                                      _mainpanel,
+                                                      _writetographics_filechooser,
+                                                      getThisFrame(),
+                                                      getContentPane(),
+                                                      _current_dir );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
+            }
+        }
+        else if ( o == _write_to_gif_item ) {
+            final File new_dir = writeToGraphicsFile( _mainpanel.getCurrentPhylogeny(),
+                                                      GraphicsExportType.GIF,
+                                                      _mainpanel,
+                                                      _writetographics_filechooser,
+                                                      getThisFrame(),
+                                                      getContentPane(),
+                                                      _current_dir );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
             }
         }
+        else if ( o == _write_to_tif_item ) {
+            final File new_dir = writeToGraphicsFile( _mainpanel.getCurrentPhylogeny(),
+                                                      GraphicsExportType.TIFF,
+                                                      _mainpanel,
+                                                      _writetographics_filechooser,
+                                                      getThisFrame(),
+                                                      getContentPane(),
+                                                      _current_dir );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
+            }
+        }
+        else if ( o == _write_to_bmp_item ) {
+            final File new_dir = writeToGraphicsFile( _mainpanel.getCurrentPhylogeny(),
+                                                      GraphicsExportType.BMP,
+                                                      _mainpanel,
+                                                      _writetographics_filechooser,
+                                                      getThisFrame(),
+                                                      getContentPane(),
+                                                      _current_dir );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
+            }
+        }
+        else if ( o == _write_to_png_item ) {
+            final File new_dir = writeToGraphicsFile( _mainpanel.getCurrentPhylogeny(),
+                                                      GraphicsExportType.PNG,
+                                                      _mainpanel,
+                                                      _writetographics_filechooser,
+                                                      getThisFrame(),
+                                                      getContentPane(),
+                                                      _current_dir );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
+            }
+        }
+        else if ( o == _print_item ) {
+            print( getCurrentTreePanel(), getOptions(), _frame.getThisFrame() );
+        }
+        else if ( o == _save_item ) {
+            final File new_dir = writeToFile( _mainpanel.getCurrentPhylogeny(),
+                                              getMainPanel(),
+                                              _save_filechooser,
+                                              _current_dir,
+                                              getContentPane(),
+                                              _frame.getThisFrame() );
+            if ( new_dir != null ) {
+                setCurrentDir( new_dir );
+            }
+        }
+        else if ( o == _graphics_export_visible_only_cbmi ) {
+            updateOptions( getOptions() );
+        }
+        else if ( o == _antialias_print_cbmi ) {
+            updateOptions( getOptions() );
+        }
+        else if ( o == _print_black_and_white_cbmi ) {
+            updateOptions( getOptions() );
+        }
+        else if ( o == _choose_pdf_width_mi ) {
+            choosePdfWidth();
+        }
+        else if ( o == _lineage_inference ) {
+            if ( isSubtreeDisplayed() ) {
+                JOptionPane.showMessageDialog( getThisFrame(),
+                                               "Subtree is shown.",
+                                               "Cannot infer ancestral taxonomies",
+                                               JOptionPane.ERROR_MESSAGE );
+                return;
+            }
+            executeLineageInference();
+        }
         else {
             if ( _load_phylogeny_from_webservice_menu_items != null ) {
                 for( int i = 0; i < _load_phylogeny_from_webservice_menu_items.length; ++i ) {
@@ -486,6 +852,7 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         _contentpane.repaint();
     }
 
+
     public Configuration getConfiguration() {
         return _configuration;
     }
@@ -495,7 +862,7 @@ public abstract class MainFrame extends JFrame implements ActionListener {
      * has been selected by the user by clicking the "Return ..."
      * menu item. This method is expected to be called from Javascript or
      * something like it.
-     * 
+     *
      * @return current external node data as String
      */
     public String getCurrentExternalNodesDataBuffer() {
@@ -547,52 +914,370 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         } );
     }
 
-    void activateSaveAllIfNeeded() {
-        if ( ( getMainPanel().getTabbedPane() != null ) && ( getMainPanel().getTabbedPane().getTabCount() > 1 ) ) {
-            _save_all_item.setEnabled( true );
+    private void annotateSequences() {
+        if ( getCurrentTreePanel() != null ) {
+            List<PhylogenyNode> nodes = null;
+            if ( ( getCurrentTreePanel().getFoundNodes0() != null )
+                    || ( getCurrentTreePanel().getFoundNodes1() != null ) ) {
+                nodes = getCurrentTreePanel().getFoundNodesAsListOfPhylogenyNodes();
+            }
+            if ( ( nodes == null ) || nodes.isEmpty() ) {
+                JOptionPane
+                        .showMessageDialog( getThisFrame(),
+                                            "Need to select nodes, either via direct selection or via the \"Search\" function",
+                                            "No nodes selected for annotation",
+                                            JOptionPane.ERROR_MESSAGE );
+                return;
+            }
+            final Phylogeny phy = getMainPanel().getCurrentPhylogeny();
+            if ( ( phy != null ) && !phy.isEmpty() ) {
+                final JTextField ref_field = new JTextField( 10 );
+                final JTextField desc_filed = new JTextField( 20 );
+                ref_field.setText( ForesterUtil.isEmpty( getPreviousNodeAnnotationReference() ) ? ""
+                        : getPreviousNodeAnnotationReference() );
+                final JPanel my_panel = new JPanel();
+                my_panel.add( new JLabel( "Reference " ) );
+                my_panel.add( ref_field );
+                my_panel.add( Box.createHorizontalStrut( 15 ) );
+                my_panel.add( new JLabel( "Description " ) );
+                my_panel.add( desc_filed );
+                final int result = JOptionPane.showConfirmDialog( null,
+                                                                  my_panel,
+                                                                  "Enter the sequence annotation(s) for the "
+                                                                          + nodes.size() + " selected nodes",
+                                                                  JOptionPane.OK_CANCEL_OPTION );
+                if ( result == JOptionPane.OK_OPTION ) {
+                    String ref = ref_field.getText();
+                    String desc = desc_filed.getText();
+                    if ( !ForesterUtil.isEmpty( ref ) ) {
+                        ref = ref.trim();
+                        ref = ref.replaceAll( "\\s+", " " );
+                        if ( ( ref.indexOf( ':' ) < 1 ) || ( ref.indexOf( ':' ) > ( ref.length() - 2 ) )
+                                || ( ref.length() < 3 ) ) {
+                            JOptionPane.showMessageDialog( getThisFrame(),
+                                                           "Reference needs to be in the form of \"GO:1234567\"",
+                                                           "Illegal Format for Annotation Reference",
+                                                           JOptionPane.ERROR_MESSAGE );
+                            return;
+                        }
+                    }
+                    if ( ref != null ) {
+                        setPreviousNodeAnnotationReference( ref );
+                    }
+                    if ( desc != null ) {
+                        desc = desc.trim();
+                        desc = desc.replaceAll( "\\s+", " " );
+                    }
+                    if ( !ForesterUtil.isEmpty( ref ) || !ForesterUtil.isEmpty( desc ) ) {
+                        for( final PhylogenyNode n : nodes ) {
+                            ForesterUtil.ensurePresenceOfSequence( n );
+                            final Annotation ann = ForesterUtil.isEmpty( ref ) ? new Annotation()
+                                    : new Annotation( ref );
+                            if ( !ForesterUtil.isEmpty( desc ) ) {
+                                ann.setDesc( desc );
+                            }
+                            n.getNodeData().getSequence().addAnnotation( ann );
+                        }
+                    }
+                    getMainPanel().getControlPanel().showAnnotations();
+                }
+            }
         }
-        else {
-            _save_all_item.setEnabled( false );
+    }
+
+    private void chooseFont() {
+        final FontChooser fc = new FontChooser();
+        fc.setFont( getMainPanel().getTreeFontSet().getLargeFont() );
+        fc.showDialog( getThisFrame(), "Select the Base Font" );
+        getMainPanel().getTreeFontSet().setBaseFont( fc.getFont() );
+        getControlPanel().displayedPhylogenyMightHaveChanged( true );
+        if ( getMainPanel().getCurrentTreePanel() != null ) {
+            getMainPanel().getCurrentTreePanel().resetPreferredSize();
+            getMainPanel().getCurrentTreePanel().updateOvSizes();
         }
+       
+        repaint();
     }
 
-    void buildFileMenu() {
-        _file_jmenu = createMenu( "File", getConfiguration() );
-        _file_jmenu.add( _open_url_item = new JMenuItem( "Read tree from URL/webservice..." ) );
-        _file_jmenu.addSeparator();
-        _file_jmenu.add( _exit_item = new JMenuItem( "Exit" ) );
-        customizeJMenuItem( _open_url_item );
-        customizeJMenuItem( _exit_item );
-        _jmenubar.add( _file_jmenu );
+    private void chooseMinimalConfidence() {
+        final String s = ( String ) JOptionPane
+                .showInputDialog( getThisFrame(),
+                                  "Please enter the minimum for confidence values to be displayed.\n"
+                                          + "[current value: " + getOptions().getMinConfidenceValue() + "]\n",
+                                  "Minimal Confidence Value",
+                                  JOptionPane.QUESTION_MESSAGE,
+                                  null,
+                                  null,
+                                  getOptions().getMinConfidenceValue() );
+        if ( !ForesterUtil.isEmpty( s ) ) {
+            boolean success = true;
+            double m = 0.0;
+            final String m_str = s.trim();
+            if ( !ForesterUtil.isEmpty( m_str ) ) {
+                try {
+                    m = Double.parseDouble( m_str );
+                }
+                catch ( final Exception ex ) {
+                    success = false;
+                }
+            }
+            else {
+                success = false;
+            }
+            if ( success && ( m >= 0.0 ) ) {
+                getOptions().setMinConfidenceValue( m );
+            }
+        }
     }
 
-    void buildFontSizeMenu() {
-        _font_size_menu = createMenu( FONT_SIZE_MENU_LABEL, getConfiguration() );
-        _font_size_menu.add( _super_tiny_fonts_item = new JMenuItem( "Super Tiny Fonts" ) );
-        _font_size_menu.add( _tiny_fonts_item = new JMenuItem( "Tiny Fonts" ) );
-        _font_size_menu.add( _small_fonts_item = new JMenuItem( "Small Fonts" ) );
-        _font_size_menu.add( _medium_fonts_item = new JMenuItem( "Medium Fonts" ) );
-        _font_size_menu.add( _large_fonts_item = new JMenuItem( "Large Fonts" ) );
-        customizeJMenuItem( _super_tiny_fonts_item );
-        customizeJMenuItem( _tiny_fonts_item );
-        customizeJMenuItem( _small_fonts_item );
-        customizeJMenuItem( _medium_fonts_item );
-        customizeJMenuItem( _large_fonts_item );
-        _jmenubar.add( _font_size_menu );
+    private void deleteSelectedNodes( final boolean delete ) {
+        final Phylogeny phy = getMainPanel().getCurrentPhylogeny();
+        if ( ( phy == null ) || ( phy.getNumberOfExternalNodes() < 2 ) ) {
+            return;
+        }
+        final List<PhylogenyNode> nodes = new ArrayList<PhylogenyNode>();
+        if ( ( getCurrentTreePanel().getFoundNodes0() != null ) || ( getCurrentTreePanel().getFoundNodes1() != null ) ) {
+            final List<PhylogenyNode> all_selected_nodes = getCurrentTreePanel().getFoundNodesAsListOfPhylogenyNodes();
+            for( final PhylogenyNode n : all_selected_nodes ) {
+                if ( n.isExternal() ) {
+                    nodes.add( n );
+                }
+            }
+        }
+        String function = "Retain";
+        if ( delete ) {
+            function = "Delete";
+        }
+        if ( ( nodes == null ) || nodes.isEmpty() ) {
+            JOptionPane
+                    .showMessageDialog( getThisFrame(),
+                                        "Need to select external nodes, either via direct selection or via the \"Search\" function",
+                                        "No external nodes selected to " + function.toLowerCase(),
+                                        JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        final int todo = nodes.size();
+        final int ext = phy.getNumberOfExternalNodes();
+        int res = todo;
+        if ( delete ) {
+            res = ext - todo;
+        }
+        if ( res < 1 ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Cannot delete all nodes",
+                                           "Attempt to delete all nodes ",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        final int result = JOptionPane.showConfirmDialog( null, function + " " + todo
+                + " external node(s), from a total of " + ext + " external nodes," + "\nresulting in tree with " + res
+                + " nodes?", function + " external nodes", JOptionPane.OK_CANCEL_OPTION );
+        if ( result == JOptionPane.OK_OPTION ) {
+            if ( !delete ) {
+                final List<PhylogenyNode> to_delete = new ArrayList<PhylogenyNode>();
+                for( final PhylogenyNodeIterator it = phy.iteratorExternalForward(); it.hasNext(); ) {
+                    final PhylogenyNode n = it.next();
+                    if ( !nodes.contains( n ) ) {
+                        to_delete.add( n );
+                    }
+                }
+                for( final PhylogenyNode n : to_delete ) {
+                    phy.deleteSubtree( n, true );
+                }
+            }
+            else {
+                for( final PhylogenyNode n : nodes ) {
+                    phy.deleteSubtree( n, true );
+                }
+            }
+            resetSearch();
+            getCurrentTreePanel().setNodeInPreorderToNull();
+            phy.externalNodesHaveChanged();
+            phy.clearHashIdToNodeMap();
+            phy.recalculateNumberOfExternalDescendants( true );
+            getCurrentTreePanel().resetNodeIdToDistToLeafMap();
+            getCurrentTreePanel().setEdited( true );
+            repaint();
+        }
     }
 
-    void buildHelpMenu() {
-        _help_jmenu = createMenu( "Help", getConfiguration() );
-        _help_jmenu.add( _help_item = new JMenuItem( "Help" ) );
-        _help_jmenu.add( _website_item = new JMenuItem( "Archaeopteryx Home" ) );
-        _aptx_ref_item = new JMenuItem( "Archaeopteryx Reference" );
-        _help_jmenu.add( _phyloxml_website_item = new JMenuItem( "phyloXML Home" ) );
-        _help_jmenu.add( _phyloxml_ref_item = new JMenuItem( "phyloXML Reference" ) );
-        _help_jmenu.addSeparator();
-        _help_jmenu.add( _about_item = new JMenuItem( "About" ) );
-        customizeJMenuItem( _help_item );
-        customizeJMenuItem( _website_item );
-        customizeJMenuItem( _phyloxml_website_item );
+    private void doUpdateProcessMenu() {
+        if ( _process_pool.size() > 0 ) {
+            if ( _process_menu == null ) {
+                _process_menu = createMenu( "", getConfiguration() );
+                _process_menu.setForeground( Color.RED );
+            }
+            _process_menu.removeAll();
+            final String text = "Processes Running: " + _process_pool.size();
+            _process_menu.setText( text );
+            _jmenubar.add( _process_menu );
+            for( int i = 0; i < _process_pool.size(); ++i ) {
+                final ProcessRunning p = _process_pool.getProcessByIndex( i );
+                _process_menu.add( customizeJMenuItem( new JMenuItem( p.getName() + " [" + p.getStart() + "]" ) ) );
+            }
+        }
+        else {
+            if ( _process_menu != null ) {
+                _process_menu.removeAll();
+                _jmenubar.remove( _process_menu );
+            }
+        }
+        _jmenubar.validate();
+        _jmenubar.repaint();
+        repaint();
+    }
+
+    private String getPreviousNodeAnnotationReference() {
+        return _previous_node_annotation_ref;
+    }
+
+    private void removeBranchColors() {
+        if ( getMainPanel().getCurrentPhylogeny() != null ) {
+            AptxUtil.removeBranchColors( getMainPanel().getCurrentPhylogeny() );
+        }
+    }
+
+    private void removeVisualStyles() {
+        if ( getMainPanel().getCurrentPhylogeny() != null ) {
+            AptxUtil.removeVisualStyles( getMainPanel().getCurrentPhylogeny() );
+        }
+    }
+
+    private void setPreviousNodeAnnotationReference( final String previous_node_annotation_ref ) {
+        _previous_node_annotation_ref = previous_node_annotation_ref;
+    }
+
+    private void writeAllToFile() {
+        if ( ( getMainPanel().getTabbedPane() == null ) || ( getMainPanel().getTabbedPane().getTabCount() < 1 ) ) {
+            return;
+        }
+        final File my_dir = getCurrentDir();
+        if ( my_dir != null ) {
+            _save_filechooser.setCurrentDirectory( my_dir );
+        }
+        _save_filechooser.setSelectedFile( new File( "" ) );
+        final int result = _save_filechooser.showSaveDialog( _contentpane );
+        final File file = _save_filechooser.getSelectedFile();
+        setCurrentDir( _save_filechooser.getCurrentDirectory() );
+        if ( ( file != null ) && ( result == JFileChooser.APPROVE_OPTION ) ) {
+            if ( file.exists() ) {
+                final int i = JOptionPane.showConfirmDialog( getThisFrame(),
+                                                             file + " already exists. Overwrite?",
+                                                             "Warning",
+                                                             JOptionPane.OK_CANCEL_OPTION,
+                                                             JOptionPane.WARNING_MESSAGE );
+                if ( i != JOptionPane.OK_OPTION ) {
+                    return;
+                }
+                else {
+                    try {
+                        file.delete();
+                    }
+                    catch ( final Exception e ) {
+                        JOptionPane.showMessageDialog( getThisFrame(),
+                                                       "Failed to delete: " + file,
+                                                       "Error",
+                                                       JOptionPane.WARNING_MESSAGE );
+                    }
+                }
+            }
+            final int count = getMainPanel().getTabbedPane().getTabCount();
+            final List<Phylogeny> trees = new ArrayList<Phylogeny>();
+            for( int i = 0; i < count; ++i ) {
+                final Phylogeny phy = getMainPanel().getPhylogeny( i );
+                if ( ForesterUtil.isEmpty( phy.getName() )
+                        && !ForesterUtil.isEmpty( getMainPanel().getTabbedPane().getTitleAt( i ) ) ) {
+                    phy.setName( getMainPanel().getTabbedPane().getTitleAt( i ) );
+                }
+                trees.add( phy );
+                getMainPanel().getTreePanels().get( i ).setEdited( false );
+            }
+            final PhylogenyWriter writer = new PhylogenyWriter();
+            try {
+                writer.toPhyloXML( file, trees, 0, ForesterUtil.LINE_SEPARATOR );
+            }
+            catch ( final IOException e ) {
+                JOptionPane.showMessageDialog( getThisFrame(),
+                                               "Failed to write to: " + file,
+                                               "Error",
+                                               JOptionPane.WARNING_MESSAGE );
+            }
+        }
+    }
+
+    public void activateSaveAllIfNeeded() {
+        if ( ( getMainPanel().getTabbedPane() != null ) && ( getMainPanel().getTabbedPane().getTabCount() > 1 ) ) {
+            _save_all_item.setEnabled( true );
+        }
+        else {
+            _save_all_item.setEnabled( false );
+        }
+    }
+
+    void buildFileMenu() {
+        _file_jmenu = MainFrame.createMenu( "File", getConfiguration() );
+        _file_jmenu.add( _save_item = new JMenuItem( "Save Tree As..." ) );
+        _file_jmenu.addSeparator();
+        _file_jmenu.add( _write_to_pdf_item = new JMenuItem( "Export to PDF file ..." ) );
+        if ( AptxUtil.canWriteFormat( "tif" ) || AptxUtil.canWriteFormat( "tiff" ) || AptxUtil.canWriteFormat( "TIF" ) ) {
+            _file_jmenu.add( _write_to_tif_item = new JMenuItem( "Export to TIFF file..." ) );
+        }
+        _file_jmenu.add( _write_to_png_item = new JMenuItem( "Export to PNG file..." ) );
+        _file_jmenu.add( _write_to_jpg_item = new JMenuItem( "Export to JPG file..." ) );
+        if ( AptxUtil.canWriteFormat( "gif" ) ) {
+            _file_jmenu.add( _write_to_gif_item = new JMenuItem( "Export to GIF file..." ) );
+        }
+        if ( AptxUtil.canWriteFormat( "bmp" ) ) {
+            _file_jmenu.add( _write_to_bmp_item = new JMenuItem( "Export to BMP file..." ) );
+        }
+        _file_jmenu.addSeparator();
+        _file_jmenu.add( _print_item = new JMenuItem( "Print..." ) );
+        _file_jmenu.addSeparator();
+        _file_jmenu.add( _exit_item = new JMenuItem( "Exit" ) );
+        customizeJMenuItem( _save_item );
+        customizeJMenuItem( _write_to_pdf_item );
+        customizeJMenuItem( _write_to_png_item );
+        customizeJMenuItem( _write_to_jpg_item );
+        customizeJMenuItem( _write_to_gif_item );
+        customizeJMenuItem( _write_to_tif_item );
+        customizeJMenuItem( _write_to_bmp_item );
+        customizeJMenuItem( _print_item );
+        customizeJMenuItem( _exit_item );
+        _jmenubar.add( _file_jmenu );
+    }
+
+    void buildFontSizeMenu() {
+        _font_size_menu = createMenu( FONT_SIZE_MENU_LABEL, getConfiguration() );
+        _font_size_menu.add( _super_tiny_fonts_item = new JMenuItem( "Super Tiny Fonts" ) );
+        _font_size_menu.add( _tiny_fonts_item = new JMenuItem( "Tiny Fonts" ) );
+        _font_size_menu.add( _small_fonts_item = new JMenuItem( "Small Fonts" ) );
+        _font_size_menu.add( _medium_fonts_item = new JMenuItem( "Medium Fonts" ) );
+        _font_size_menu.add( _large_fonts_item = new JMenuItem( "Large Fonts" ) );
+        customizeJMenuItem( _super_tiny_fonts_item );
+        customizeJMenuItem( _tiny_fonts_item );
+        customizeJMenuItem( _small_fonts_item );
+        customizeJMenuItem( _medium_fonts_item );
+        customizeJMenuItem( _large_fonts_item );
+        _jmenubar.add( _font_size_menu );
+    }
+
+    void buildHelpMenu() {
+        _help_jmenu = createMenu( "Help", getConfiguration() );
+        _help_jmenu.add( _help_item = new JMenuItem( "Documentation" ) );
+        _help_jmenu.addSeparator();
+        _help_jmenu.add( _website_item = new JMenuItem( "Archaeopteryx Home" ) );
+        _help_jmenu.add( _aptxjs_website_item = new JMenuItem( "NEW! Archaeopteryx online version: Archaeopteryx.js" ) );
+        _help_jmenu.add( _mailing_list_item = new JMenuItem( "Mailing List" ) );
+        _aptx_ref_item = new JMenuItem( "Archaeopteryx Reference" ); //TODO need to add this...
+        _help_jmenu.add( _phyloxml_website_item = new JMenuItem( "phyloXML Home" ) );
+        _help_jmenu.add( _phyloxml_ref_item = new JMenuItem( "phyloXML Reference" ) );
+        _help_jmenu.addSeparator();
+        _help_jmenu.add( _about_item = new JMenuItem( "About" ) );
+        customizeJMenuItem( _help_item );
+        customizeJMenuItem( _website_item );
+        customizeJMenuItem( _aptxjs_website_item );
+        customizeJMenuItem( _mailing_list_item );
+        customizeJMenuItem( _phyloxml_website_item );
         customizeJMenuItem( _aptx_ref_item );
         customizeJMenuItem( _phyloxml_ref_item );
         customizeJMenuItem( _about_item );
@@ -619,6 +1304,8 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         customizeCheckBoxMenuItem( _convex_type_cbmi, false );
         customizeCheckBoxMenuItem( _unrooted_type_cbmi, false );
         customizeCheckBoxMenuItem( _circular_type_cbmi, false );
+        _triangular_type_cbmi.setToolTipText( "not suitable for phylograms" );
+        _curved_type_cbmi.setToolTipText( "not suitable for phylograms" );
         _unrooted_type_cbmi.setToolTipText( MainFrame.USE_MOUSEWHEEL_SHIFT_TO_ROTATE );
         _circular_type_cbmi.setToolTipText( MainFrame.USE_MOUSEWHEEL_SHIFT_TO_ROTATE );
         initializeTypeMenu( getOptions() );
@@ -627,11 +1314,11 @@ public abstract class MainFrame extends JFrame implements ActionListener {
 
     void buildViewMenu() {
         _view_jmenu = createMenu( "View", getConfiguration() );
-        _view_jmenu.add( _display_basic_information_item = new JMenuItem( "Display Basic Information" ) );
+        _view_jmenu.add( _display_basic_information_item = new JMenuItem( SHOW_BASIC_TREE_INFORMATION_LABEL ) );
         _view_jmenu.addSeparator();
-        _view_jmenu.add( _view_as_XML_item = new JMenuItem( "View as phyloXML" ) );
-        _view_jmenu.add( _view_as_NH_item = new JMenuItem( "View as Newick" ) );
-        _view_jmenu.add( _view_as_nexus_item = new JMenuItem( "View as Nexus" ) );
+        _view_jmenu.add( _view_as_XML_item = new JMenuItem( "as phyloXML" ) );
+        _view_jmenu.add( _view_as_NH_item = new JMenuItem( "as Newick" ) );
+        _view_jmenu.add( _view_as_nexus_item = new JMenuItem( "as Nexus" ) );
         customizeJMenuItem( _display_basic_information_item );
         customizeJMenuItem( _view_as_NH_item );
         customizeJMenuItem( _view_as_XML_item );
@@ -655,6 +1342,37 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
+    void choosePdfWidth() {
+        final String s = ( String ) JOptionPane.showInputDialog( getThisFrame(),
+                                                                 "Please enter the default line width for PDF export.\n"
+                                                                         + "[current value: "
+                                                                         + getOptions().getPrintLineWidth() + "]\n",
+                                                                 "Line Width for PDF Export",
+                                                                 JOptionPane.QUESTION_MESSAGE,
+                                                                 null,
+                                                                 null,
+                                                                 getOptions().getPrintLineWidth() );
+        if ( !ForesterUtil.isEmpty( s ) ) {
+            boolean success = true;
+            float f = 0.0f;
+            final String m_str = s.trim();
+            if ( !ForesterUtil.isEmpty( m_str ) ) {
+                try {
+                    f = Float.parseFloat( m_str );
+                }
+                catch ( final Exception ex ) {
+                    success = false;
+                }
+            }
+            else {
+                success = false;
+            }
+            if ( success && ( f > 0.0 ) ) {
+                getOptions().setPrintLineWidth( f );
+            }
+        }
+    }
+
     void close() {
         removeAllTextFrames();
         if ( _mainpanel != null ) {
@@ -669,9 +1387,10 @@ public abstract class MainFrame extends JFrame implements ActionListener {
 
     void colorRank() {
         if ( _mainpanel.getCurrentTreePanel() != null ) {
-            final String[] ranks = AptxUtil.getAllPossibleRanks();
-            final String rank = ( String ) JOptionPane
-                    .showInputDialog( this,
+            final Map<String, Integer> present_ranks = AptxUtil.getRankCounts( _mainpanel.getCurrentTreePanel().getPhylogeny());
+            final String[] ranks = AptxUtil.getAllPossibleRanks(present_ranks);
+            String rank = ( String ) JOptionPane
+                    .showInputDialog( getThisFrame(),
                                       "What rank should the colorization be based on",
                                       "Rank Selection",
                                       JOptionPane.QUESTION_MESSAGE,
@@ -679,6 +1398,9 @@ public abstract class MainFrame extends JFrame implements ActionListener {
                                       ranks,
                                       null );
             if ( !ForesterUtil.isEmpty( rank ) ) {
+                if ( rank.indexOf( '(' ) > 0 ) {
+                    rank = rank.substring( 0, rank.indexOf( '(' ) ).trim();
+                }
                 _mainpanel.getCurrentTreePanel().colorRank( rank );
             }
         }
@@ -726,13 +1448,13 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
-    void displayBasicInformation() {
+    void displayBasicInformation( final File treefile ) {
         if ( ( _mainpanel.getCurrentPhylogeny() != null ) && !_mainpanel.getCurrentPhylogeny().isEmpty() ) {
             String title = "Basic Information";
             if ( !ForesterUtil.isEmpty( _mainpanel.getCurrentPhylogeny().getName() ) ) {
-                title = _mainpanel.getCurrentPhylogeny().getName() + " " + title;
+                title = title + " for \"" + _mainpanel.getCurrentPhylogeny().getName() + "\"";
             }
-            showTextFrame( AptxUtil.createBasicInformation( _mainpanel.getCurrentPhylogeny() ), title );
+            showTextFrame( AptxUtil.createBasicInformation( _mainpanel.getCurrentPhylogeny(), treefile ), title );
         }
     }
 
@@ -743,32 +1465,182 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         catch ( final Exception ex ) {
             // Do nothing.
         }
-        JOptionPane.showMessageDialog( this,
+        JOptionPane.showMessageDialog( getThisFrame(),
                                        ForesterUtil.wordWrap( e.getLocalizedMessage(), 80 ),
                                        "Error during File|Open",
                                        JOptionPane.ERROR_MESSAGE );
     }
 
-    void exceptionOccuredDuringSaveAs( final Exception e ) {
+    void executeGSDI() {
+        if ( !isOKforSDI( false, true ) ) {
+            return;
+        }
+        if ( !_mainpanel.getCurrentPhylogeny().isRooted() ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Gene tree is not rooted.",
+                                           "Cannot execute GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        final Phylogeny gene_tree = _mainpanel.getCurrentPhylogeny().copy();
+        gene_tree.setAllNodesToNotCollapse();
+        gene_tree.recalculateNumberOfExternalDescendants( false );
+        GSDI gsdi = null;
+        final Phylogeny species_tree = getSpeciesTree().copy();
         try {
-            _mainpanel.getCurrentTreePanel().setArrowCursor();
+            gsdi = new GSDI( gene_tree, species_tree, false, true, true, true );
         }
-        catch ( final Exception ex ) {
-            // Do nothing.
+        catch ( final SDIException e ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           e.getLocalizedMessage(),
+                                           "Error during GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        catch ( final Exception e ) {
+            AptxUtil.unexpectedException( e );
+            return;
+        }
+        gene_tree.setRerootable( false );
+        gene_tree.clearHashIdToNodeMap();
+        gene_tree.recalculateNumberOfExternalDescendants( true );
+        _mainpanel.addPhylogenyInNewTab( gene_tree, getConfiguration(), "gene tree", null );
+        getMainPanel().getControlPanel().setShowEvents( true );
+        showWhole();
+        final int selected = _mainpanel.getTabbedPane().getSelectedIndex();
+        _mainpanel.addPhylogenyInNewTab( species_tree, getConfiguration(), "species tree", null );
+        showWhole();
+        _mainpanel.getTabbedPane().setSelectedIndex( selected );
+        showWhole();
+        _mainpanel.getCurrentTreePanel().setEdited( true );
+        final int poly = PhylogenyMethods.countNumberOfPolytomies( species_tree );
+        if ( gsdi.getStrippedExternalGeneTreeNodes().size() > 0 ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Duplications: " + gsdi.getDuplicationsSum() + "\n"
+                                                   + "Potential duplications: "
+                                                   + gsdi.getSpeciationOrDuplicationEventsSum() + "\n"
+                                                   + "Speciations: " + gsdi.getSpeciationsSum() + "\n"
+                                                   + "Stripped gene tree nodes: "
+                                                   + gsdi.getStrippedExternalGeneTreeNodes().size() + "\n"
+                                                   + "Taxonomy linkage based on: " + gsdi.getTaxCompBase() + "\n"
+                                                   + "Number of polytomies in species tree used: " + poly + "\n",
+                                           "GSDI successfully completed",
+                                           JOptionPane.WARNING_MESSAGE );
+        }
+        else {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Duplications: " + gsdi.getDuplicationsSum() + "\n"
+                                                   + "Potential duplications: "
+                                                   + gsdi.getSpeciationOrDuplicationEventsSum() + "\n"
+                                                   + "Speciations: " + gsdi.getSpeciationsSum() + "\n"
+                                                   + "Stripped gene tree nodes: "
+                                                   + gsdi.getStrippedExternalGeneTreeNodes().size() + "\n"
+                                                   + "Taxonomy linkage based on: " + gsdi.getTaxCompBase() + "\n"
+                                                   + "Number of polytomies in species tree used: " + poly + "\n",
+                                           "GSDI successfully completed",
+                                           JOptionPane.INFORMATION_MESSAGE );
+        }
+    }
+
+    void executeGSDIR() {
+        if ( !isOKforSDI( false, false ) ) {
+            return;
+        }
+        final int p = PhylogenyMethods.countNumberOfPolytomies( _mainpanel.getCurrentPhylogeny() );
+        if ( ( p > 0 )
+                && !( ( p == 1 ) && ( _mainpanel.getCurrentPhylogeny().getRoot().getNumberOfDescendants() == 3 ) ) ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Gene tree is not completely binary",
+                                           "Cannot execute GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        final Phylogeny gene_tree = _mainpanel.getCurrentPhylogeny().copy();
+        gene_tree.setAllNodesToNotCollapse();
+        gene_tree.recalculateNumberOfExternalDescendants( false );
+        GSDIR gsdir = null;
+        final Phylogeny species_tree = getSpeciesTree().copy();
+        try {
+            gsdir = new GSDIR( gene_tree, species_tree, true, true, true );
         }
-        JOptionPane.showMessageDialog( this, "Exception" + e, "Error during File|SaveAs", JOptionPane.ERROR_MESSAGE );
+        catch ( final SDIException e ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           e.getLocalizedMessage(),
+                                           "Error during GSDIR",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        catch ( final Exception e ) {
+            AptxUtil.unexpectedException( e );
+            return;
+        }
+        final Phylogeny result_gene_tree = gsdir.getMinDuplicationsSumGeneTree();
+        result_gene_tree.setRerootable( false );
+        result_gene_tree.clearHashIdToNodeMap();
+        result_gene_tree.recalculateNumberOfExternalDescendants( true );
+        PhylogenyMethods.orderAppearance( result_gene_tree.getRoot(), true, true, DESCENDANT_SORT_PRIORITY.NODE_NAME );
+        _mainpanel.addPhylogenyInNewTab( result_gene_tree, getConfiguration(), "gene tree", null );
+        getMainPanel().getControlPanel().setShowEvents( true );
+        showWhole();
+        final int selected = _mainpanel.getTabbedPane().getSelectedIndex();
+        _mainpanel.addPhylogenyInNewTab( species_tree, getConfiguration(), "species tree", null );
+        showWhole();
+        _mainpanel.getTabbedPane().setSelectedIndex( selected );
+        showWhole();
+        _mainpanel.getCurrentTreePanel().setEdited( true );
+        final int poly = PhylogenyMethods.countNumberOfPolytomies( species_tree );
+        if ( gsdir.getStrippedExternalGeneTreeNodes().size() > 0 ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Minimal duplications: " + gsdir.getMinDuplicationsSum() + "\n"
+                                                   + "Speciations: " + gsdir.getSpeciationsSum() + "\n"
+                                                   + "Stripped gene tree nodes: "
+                                                   + gsdir.getStrippedExternalGeneTreeNodes().size() + "\n"
+                                                   + "Taxonomy linkage based on: " + gsdir.getTaxCompBase() + "\n"
+                                                   + "Number of polytomies in species tree used: " + poly + "\n",
+                                           "GSDIR successfully completed",
+                                           JOptionPane.WARNING_MESSAGE );
+        }
+        else {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Minimal duplications: " + gsdir.getMinDuplicationsSum() + "\n"
+                                                   + "Speciations: " + gsdir.getSpeciationsSum() + "\n"
+                                                   + "Stripped gene tree nodes: "
+                                                   + gsdir.getStrippedExternalGeneTreeNodes().size() + "\n"
+                                                   + "Taxonomy linkage based on: " + gsdir.getTaxCompBase() + "\n"
+                                                   + "Number of polytomies in species tree used: " + poly + "\n",
+                                           "GSDIR successfully completed",
+                                           JOptionPane.INFORMATION_MESSAGE );
+        }
+    }
+
+    void executeLineageInference() {
+        if ( ( _mainpanel.getCurrentPhylogeny() == null ) || ( _mainpanel.getCurrentPhylogeny().isEmpty() ) ) {
+            return;
+        }
+        if ( !_mainpanel.getCurrentPhylogeny().isRooted() ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Phylogeny is not rooted.",
+                                           "Cannot infer ancestral taxonomies",
+                                           JOptionPane.ERROR_MESSAGE );
+            return;
+        }
+        final AncestralTaxonomyInferrer inferrer = new AncestralTaxonomyInferrer( this,
+                                                                                  _mainpanel.getCurrentTreePanel(),
+                                                                                  _mainpanel.getCurrentPhylogeny()
+                                                                                          .copy() );
+        new Thread( inferrer ).start();
     }
 
     boolean GAndSDoHaveMoreThanOneSpeciesInComman( final Phylogeny gene_tree ) {
         if ( ( gene_tree == null ) || gene_tree.isEmpty() ) {
-            JOptionPane.showMessageDialog( this,
+            JOptionPane.showMessageDialog( getThisFrame(),
                                            "Gene tree and species tree have no species in common.",
                                            "Error during SDI",
                                            JOptionPane.ERROR_MESSAGE );
             return false;
         }
         else if ( gene_tree.getNumberOfExternalNodes() < 2 ) {
-            JOptionPane.showMessageDialog( this,
+            JOptionPane.showMessageDialog( getThisFrame(),
                                            "Gene tree and species tree have only one species in common.",
                                            "Error during SDI",
                                            JOptionPane.ERROR_MESSAGE );
@@ -779,6 +1651,32 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
+    ControlPanel getControlPanel() {
+        return getMainPanel().getControlPanel();
+    }
+
+    File getCurrentDir() {
+        if ( ( _current_dir == null ) || !_current_dir.canRead() ) {
+            if ( ForesterUtil.isWindows() ) {
+                try {
+                    _current_dir = new File( WindowsUtils.getCurrentUserDesktopPath() );
+                }
+                catch ( final Exception e ) {
+                    _current_dir = null;
+                }
+            }
+        }
+        if ( ( _current_dir == null ) || !_current_dir.canRead() ) {
+            if ( System.getProperty( "user.home" ) != null ) {
+                _current_dir = new File( System.getProperty( "user.home" ) );
+            }
+            else if ( System.getProperty( "user.dir" ) != null ) {
+                _current_dir = new File( System.getProperty( "user.dir" ) );
+            }
+        }
+        return _current_dir;
+    }
+
     TreePanel getCurrentTreePanel() {
         return getMainPanel().getCurrentTreePanel();
     }
@@ -795,102 +1693,8 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         return _jmenubar;
     }
 
-    void help( final Map<String, WebLink> weblinks ) {
-        final StringBuilder sb = new StringBuilder();
-        sb.append( "Display options\n" );
-        sb.append( "-------------------\n" );
-        sb.append( "Use the checkboxes to select types of information to display on the tree.\n\n" );
-        sb.append( "Clickable tree nodes\n" );
-        sb.append( "--------------------\n" );
-        sb.append( "Tree nodes can be clicked, the action is determined by the 'click on node to' menu\n" );
-        sb.append( "or by right clicking:\n" );
-        sb.append( "o  Display Node Data -- display information for a node\n" );
-        sb.append( "o  Collapse/Uncollapse -- collapse and uncollapse subtree from clicked node\n" );
-        sb.append( "o  Root/Reroot -- change tree root to clicked node\n" );
-        sb.append( "o  Sub/Super Tree -- toggle between subtree from clicked node and whole tree\n" );
-        sb.append( "o  Swap Descendants -- switch descendant on either side of clicked node\n" );
-        sb.append( "o  Colorize Subtree -- color a subtree\n" );
-        sb.append( "o  Open Sequence Web -- launch a web browser to display sequence information\n" );
-        sb.append( "o  Open Taxonomy Web -- launch a web browser to display taxonomy information\n" );
-        sb.append( "-  there may be additional choices depending on this particular setup\n\n" );
-        sb.append( "Right clicking on a node always displays the information of a node.\n\n" );
-        sb.append( "Zooming\n" );
-        sb.append( "---------\n" );
-        sb.append( "The mouse wheel and the plus and minus keys control zooming.\n" );
-        sb.append( "Mouse wheel+Ctrl changes the text size.\n" );
-        sb.append( "Mouse wheel+Shift controls zooming in vertical direction only.\n" );
-        sb.append( "Use the buttons on the control panel to zoom the tree in and out, horizontally or vertically.\n" );
-        sb.append( "The entire tree can be fitted into the window by clicking the \"F\" button, or by pressing F, Delete, or Home.\n" );
-        sb.append( "The up, down, left, and right keys can be used to move the visible part (if zoomed in).\n" );
-        sb.append( "Up, down, left, and right+Shift can be used to control zooming horizontally and vertically.\n" );
-        sb.append( "Plus and minus keys+Ctrl change the text size; F+Ctrl, Delete+Ctrl, or Home+Ctrl resets it.\n\n" );
-        sb.append( "Quick tree manipulation:\n" );
-        sb.append( "------------------------\n" );
-        sb.append( "Order Subtrees -- order the tree by branch length\n" );
-        sb.append( "Uncollapse All -- uncollapse any and all collapsed branches\n\n" );
-        sb.append( "Memory problems (Java heap space error)\n" );
-        sb.append( "---------------------------------------\n" );
-        sb.append( "Since the Java default memory allocation is quite small, it might by necessary (for trees\n" );
-        sb.append( "with more than approximately 5000 external nodes) to increase the memory which Java can use, with\n" );
-        sb.append( "the '-Xmx' Java command line option. For example:\n" );
-        sb.append( "java -Xms32m -Xmx256m -cp path\\to\\forester.jar org.forester.archaeopteryx.Archaeopteryx\n\n" );
-        if ( ( weblinks != null ) && ( weblinks.size() > 0 ) ) {
-            sb.append( "Active web links\n" );
-            sb.append( "--------------------\n" );
-            for( final String key : weblinks.keySet() ) {
-                sb.append( " " + weblinks.get( key ).toString() + "\n" );
-            }
-        }
-        // + "General remarks\n"
-        // + "---------------\n"
-        // +
-        // "o  The application version permits copying to the clipboard \n"
-        // +
-        // "    in the \"View\"|\"View as ...\" frame (either by control-c or button press).\n"
-        // +
-        // "o  Changes made to a subtree affect this subtree and its subtrees,\n"
-        // + "    but not any of its parent tree(s).\n"
-        // +
-        // "o  Archaeopteryx tries to detect whether the numerical values in a NH tree\n"
-        // +
-        // "    are likely to be bootstrap values instead of branch length values.\n\n"
-        // +
-        // " Remarks regarding SDI (Speciation Duplication Inference):\n"
-        // +
-        // "o  Each external node of the gene tree (in display) needs to be associated with\n"
-        // +
-        // "    a species: either directly through the \"Species\" field, or the species\n"
-        // +
-        // "    is part of the sequence name in the form \"XXXX_SPECIES\"\n"
-        // +
-        // "    (e.g. \"ACON_DROME\" or \"ACON_DROME/123-4489\" which is also acceptable).\n"
-        // +
-        // "o  A species tree for each species of the gene tree needs to be loaded with\n"
-        // +
-        // "   \"SDI\"|\"Load species tree\" prior the SDI execution.\n"
-        // +
-        // "o  !External nodes of the gene tree associated with species not present in\n"
-        // +
-        // "    the species tree are REMOVED prior to SDI execution!\n"
-        // +
-        // "o  Both the gene tree and the species tree must be completely binary.\n"
-        // +
-        // "o  Duplications and speciations are a function of the position of the root.\n"
-        // +
-        // "    Hence, after each manual \"Root/Reroot\"ing some duplications will be\n"
-        // + "    incorrect and need to be inferred again\n"
-        // +
-        // "    with: \"SDI\"|\"SDI (Speciation Duplication Inference)\n\n"
-        sb.append( "\n" );
-        sb.append( "phyloXML\n" );
-        sb.append( "-------------------\n" );
-        sb.append( "Reference: " + Constants.PHYLOXML_REFERENCE + "\n" );
-        sb.append( "Website: " + Constants.PHYLOXML_WEB_SITE + "\n" );
-        sb.append( "Version: " + ForesterConstants.PHYLO_XML_VERSION + "\n" );
-        sb.append( "\n" );
-        sb.append( "For more information: https://sites.google.com/site/cmzmasek/home/software/archaeopteryx\n" );
-        sb.append( "Email: " + Constants.AUTHOR_EMAIL + "\n\n" );
-        TextFrame.instantiate( sb.toString(), "Help", _textframes );
+    final Phylogeny getSpeciesTree() {
+        return _species_tree;
     }
 
     void initializeTypeMenu( final Options options ) {
@@ -923,11 +1727,41 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
+    boolean isOKforSDI( final boolean species_tree_has_to_binary, final boolean gene_tree_has_to_binary ) {
+        if ( ( _mainpanel.getCurrentPhylogeny() == null ) || _mainpanel.getCurrentPhylogeny().isEmpty() ) {
+            return false;
+        }
+        else if ( ( getSpeciesTree() == null ) || getSpeciesTree().isEmpty() ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "No species tree loaded",
+                                           "Cannot execute GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return false;
+        }
+        else if ( species_tree_has_to_binary && !getSpeciesTree().isCompletelyBinary() ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Species tree is not completely binary",
+                                           "Cannot execute GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return false;
+        }
+        else if ( gene_tree_has_to_binary && !_mainpanel.getCurrentPhylogeny().isCompletelyBinary() ) {
+            JOptionPane.showMessageDialog( getThisFrame(),
+                                           "Gene tree is not completely binary",
+                                           "Cannot execute GSDI",
+                                           JOptionPane.ERROR_MESSAGE );
+            return false;
+        }
+        else {
+            return true;
+        }
+    }
+
     boolean isSubtreeDisplayed() {
         if ( getCurrentTreePanel() != null ) {
             if ( getCurrentTreePanel().isCurrentTreeIsSubtree() ) {
                 JOptionPane
-                        .showMessageDialog( this,
+                        .showMessageDialog( getThisFrame(),
                                             "This operation can only be performed on a complete tree, not on the currently displayed sub-tree only.",
                                             "Operation can not be exectuted on a sub-tree",
                                             JOptionPane.WARNING_MESSAGE );
@@ -943,8 +1777,6 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
-    abstract void readPhylogeniesFromURL();
-
     void readPhylogeniesFromWebservice( final int i ) {
         final UrlTreeReader reader = new UrlTreeReader( this, i );
         new Thread( reader ).start();
@@ -959,10 +1791,29 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         _textframes.clear();
     }
 
+    void resetSearch() {
+        getMainPanel().getCurrentTreePanel().setFoundNodes0( null );
+        getMainPanel().getCurrentTreePanel().setFoundNodes1( null );
+        getMainPanel().getControlPanel().setSearchFoundCountsOnLabel0( 0 );
+        getMainPanel().getControlPanel().getSearchFoundCountsLabel0().setVisible( false );
+        getMainPanel().getControlPanel().getSearchTextField0().setText( "" );
+        getMainPanel().getControlPanel().getSearchResetButton0().setEnabled( false );
+        getMainPanel().getControlPanel().getSearchResetButton0().setVisible( false );
+        getMainPanel().getControlPanel().setSearchFoundCountsOnLabel1( 0 );
+        getMainPanel().getControlPanel().getSearchFoundCountsLabel1().setVisible( false );
+        getMainPanel().getControlPanel().getSearchTextField1().setText( "" );
+        getMainPanel().getControlPanel().getSearchResetButton1().setEnabled( false );
+        getMainPanel().getControlPanel().getSearchResetButton1().setVisible( false );
+    }
+
     void setConfiguration( final Configuration configuration ) {
         _configuration = configuration;
     }
 
+    void setCurrentDir( final File current_dir ) {
+        _current_dir = current_dir;
+    }
+
     void setInferenceManager( final InferenceManager i ) {
         _inference_manager = i;
     }
@@ -1003,6 +1854,10 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
+    final void setSpeciesTree( final Phylogeny species_tree ) {
+        _species_tree = species_tree;
+    }
+
     void setTypeMenuToAllUnselected() {
         _convex_type_cbmi.setSelected( false );
         _curved_type_cbmi.setSelected( false );
@@ -1062,6 +1917,8 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         options.setBackgroundColorGradient( ( _background_gradient_cbmi != null )
                 && _background_gradient_cbmi.isSelected() );
         options.setShowDomainLabels( ( _show_domain_labels != null ) && _show_domain_labels.isSelected() );
+        options.setShowAnnotationRefSource( ( _show_annotation_ref_source != null )
+                && _show_annotation_ref_source.isSelected() );
         options.setAbbreviateScientificTaxonNames( ( _abbreviate_scientific_names != null )
                 && _abbreviate_scientific_names.isSelected() );
         options.setColorLabelsSameAsParentBranch( ( _color_labels_same_as_parent_branch != null )
@@ -1070,16 +1927,13 @@ public abstract class MainFrame extends JFrame implements ActionListener {
                 && _show_default_node_shapes_internal_cbmi.isSelected() );
         options.setShowDefaultNodeShapesExternal( ( _show_default_node_shapes_external_cbmi != null )
                 && _show_default_node_shapes_external_cbmi.isSelected() );
-        options.setTaxonomyColorizeNodeShapes( ( _taxonomy_colorize_node_shapes_cbmi != null )
-                && _taxonomy_colorize_node_shapes_cbmi.isSelected() );
+        options.setShowDefaultNodeShapesForMarkedNodes( ( _show_default_node_shapes_for_marked_cbmi != null )
+                && _show_default_node_shapes_for_marked_cbmi.isSelected() );
         if ( ( _non_lined_up_cladograms_rbmi != null ) && ( _non_lined_up_cladograms_rbmi.isSelected() ) ) {
             options.setCladogramType( CLADOGRAM_TYPE.NON_LINED_UP );
         }
-        else if ( ( _uniform_cladograms_rbmi != null ) && ( _uniform_cladograms_rbmi.isSelected() ) ) {
-            options.setCladogramType( CLADOGRAM_TYPE.TOTAL_NODE_SUM_DEP );
-        }
         else if ( ( _ext_node_dependent_cladogram_rbmi != null ) && ( _ext_node_dependent_cladogram_rbmi.isSelected() ) ) {
-            options.setCladogramType( CLADOGRAM_TYPE.EXT_NODE_SUM_DEP );
+            options.setCladogramType( CLADOGRAM_TYPE.LINED_UP );
         }
         options.setSearchCaseSensitive( ( _search_case_senstive_cbmi != null )
                 && _search_case_senstive_cbmi.isSelected() );
@@ -1097,13 +1951,9 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         options.setShowOverview( ( _show_overview_cbmi != null ) && _show_overview_cbmi.isSelected() );
         options.setShowConfidenceStddev( ( _show_confidence_stddev_cbmi != null )
                 && _show_confidence_stddev_cbmi.isSelected() );
-        if ( ( _show_branch_length_values_cbmi != null ) && _show_branch_length_values_cbmi.isEnabled() ) {
-            options.setShowBranchLengthValues( _show_branch_length_values_cbmi.isSelected() );
+        if ( ( _color_by_taxonomic_group_cbmi != null ) && _color_by_taxonomic_group_cbmi.isEnabled() ) {
+            options.setColorByTaxonomicGroup( _color_by_taxonomic_group_cbmi.isSelected() );
         }
-        options.setPrintUsingActualSize( ( _print_using_actual_size_cbmi != null )
-                && ( _print_using_actual_size_cbmi.isSelected() ) );
-        options.setGraphicsExportUsingActualSize( ( _graphics_export_using_actual_size_cbmi != null )
-                && ( _graphics_export_using_actual_size_cbmi.isSelected() ) );
         options.setAntialiasPrint( ( _antialias_print_cbmi != null ) && _antialias_print_cbmi.isSelected() );
         if ( ( _use_brackets_for_conf_in_nh_export_cbmi != null )
                 && _use_brackets_for_conf_in_nh_export_cbmi.isSelected() ) {
@@ -1120,30 +1970,29 @@ public abstract class MainFrame extends JFrame implements ActionListener {
                 && _print_black_and_white_cbmi.isSelected() );
         options.setInternalNumberAreConfidenceForNhParsing( ( _internal_number_are_confidence_for_nh_parsing_cbmi != null )
                 && _internal_number_are_confidence_for_nh_parsing_cbmi.isSelected() );
-        if ( ( _extract_taxonomy_yes_rbmi != null ) && _extract_taxonomy_yes_rbmi.isSelected() ) {
-            options.setTaxonomyExtractio( TAXONOMY_EXTRACTION.AGRESSIVE );
+        if ( ( _extract_taxonomy_pfam_strict_rbmi != null ) && _extract_taxonomy_pfam_strict_rbmi.isSelected() ) {
+            options.setTaxonomyExtraction( TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
         }
-        else if ( ( _extract_taxonomy_pfam_rbmi != null ) && _extract_taxonomy_pfam_rbmi.isSelected() ) {
-            options.setTaxonomyExtractio( TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
+        else if ( ( _extract_taxonomy_pfam_relaxed_rbmi != null ) && _extract_taxonomy_pfam_relaxed_rbmi.isSelected() ) {
+            options.setTaxonomyExtraction( TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+        }
+        else if ( ( _extract_taxonomy_agressive_rbmi != null ) && _extract_taxonomy_agressive_rbmi.isSelected() ) {
+            options.setTaxonomyExtraction( TAXONOMY_EXTRACTION.AGGRESSIVE );
         }
         else if ( ( _extract_taxonomy_no_rbmi != null ) && _extract_taxonomy_no_rbmi.isSelected() ) {
-            options.setTaxonomyExtractio( TAXONOMY_EXTRACTION.NO );
+            options.setTaxonomyExtraction( TAXONOMY_EXTRACTION.NO );
         }
         options.setReplaceUnderscoresInNhParsing( ( _replace_underscores_cbmi != null )
                 && _replace_underscores_cbmi.isSelected() );
+        options.setAllowErrorsInDistanceToParent( ( _allow_errors_in_distance_to_parent_cbmi != null )
+                && _allow_errors_in_distance_to_parent_cbmi.isSelected() );
         options.setMatchWholeTermsOnly( ( _search_whole_words_only_cbmi != null )
                 && _search_whole_words_only_cbmi.isSelected() );
+        options.setSearchWithRegex( ( _search_with_regex_cbmi != null ) && _search_with_regex_cbmi.isSelected() );
         options.setInverseSearchResult( ( _inverse_search_result_cbmi != null )
                 && _inverse_search_result_cbmi.isSelected() );
         if ( _graphics_export_visible_only_cbmi != null ) {
-            options.setGraphicsExportVisibleOnly( _graphics_export_visible_only_cbmi.isSelected() );
-            if ( _graphics_export_visible_only_cbmi.isSelected() && ( _graphics_export_using_actual_size_cbmi != null ) ) {
-                _graphics_export_using_actual_size_cbmi.setSelected( true );
-                _graphics_export_using_actual_size_cbmi.setEnabled( false );
-            }
-            else {
-                _graphics_export_using_actual_size_cbmi.setEnabled( true );
-            }
+            options.setGraphicsExportVisibleOnly( _graphics_export_visible_only_cbmi.isSelected() );    
         }
         if ( ( _rectangular_type_cbmi != null ) && _rectangular_type_cbmi.isSelected() ) {
             options.setPhylogenyGraphicsType( PHYLOGENY_GRAPHICS_TYPE.RECTANGULAR );
@@ -1169,6 +2018,25 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         else if ( ( _circular_type_cbmi != null ) && _circular_type_cbmi.isSelected() ) {
             options.setPhylogenyGraphicsType( PHYLOGENY_GRAPHICS_TYPE.CIRCULAR );
         }
+        if ( ( _right_line_up_domains_cbmi != null ) && _right_line_up_domains_cbmi.isEnabled() ) {
+            options.setRightLineUpDomains( _right_line_up_domains_cbmi.isSelected() );
+        }
+        if ( ( _line_up_renderable_data_cbmi != null ) && _line_up_renderable_data_cbmi.isEnabled() ) {
+            options.setLineUpRendarableNodeData( _line_up_renderable_data_cbmi.isSelected() );
+        }
+        if ( ( _color_all_found_nodes_when_coloring_subtree_cbmi != null ) && _color_all_found_nodes_when_coloring_subtree_cbmi.isEnabled() ) {
+            options.setColorAllFoundNodesWhenColoringSubtree( _color_all_found_nodes_when_coloring_subtree_cbmi.isSelected() );
+        }
+        if ( ( _parse_beast_style_extended_nexus_tags_cbmi != null ) && _parse_beast_style_extended_nexus_tags_cbmi.isEnabled() ) {
+            options.setParseBeastStyleExtendedNexusTags(_parse_beast_style_extended_nexus_tags_cbmi.isSelected() );
+        }
+        if ( ( _collapsed_with_average_height_cbmi != null ) && _collapsed_with_average_height_cbmi.isEnabled() ) {
+            options.setCollapsedWithAverageHeigh(_collapsed_with_average_height_cbmi.isSelected() );
+        }
+        if ( ( _show_abbreviated_labels_for_collapsed_nodes_cbmi != null ) && _show_abbreviated_labels_for_collapsed_nodes_cbmi.isEnabled() ) {
+            options.setShowAbbreviatedLabelsForCollapsedNodes(_show_abbreviated_labels_for_collapsed_nodes_cbmi.isSelected() );
+        }
+        
     }
 
     void updateTypeCheckboxes( final Options options, final Object o ) {
@@ -1180,7 +2048,7 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         if ( ( _mainpanel.getCurrentPhylogeny() != null ) && !_mainpanel.getCurrentPhylogeny().isEmpty() ) {
             String title = "Nexus";
             if ( !ForesterUtil.isEmpty( _mainpanel.getCurrentPhylogeny().getName() ) ) {
-                title = _mainpanel.getCurrentPhylogeny().getName() + " " + title;
+                title = "\"" + getMainPanel().getCurrentPhylogeny().getName() + "\" in " + title;
             }
             showTextFrame( _mainpanel.getCurrentPhylogeny().toNexus( getOptions().getNhConversionSupportValueStyle() ),
                            title );
@@ -1191,10 +2059,10 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         if ( ( _mainpanel.getCurrentPhylogeny() != null ) && !_mainpanel.getCurrentPhylogeny().isEmpty() ) {
             String title = "New Hampshire";
             if ( !ForesterUtil.isEmpty( _mainpanel.getCurrentPhylogeny().getName() ) ) {
-                title = _mainpanel.getCurrentPhylogeny().getName() + " " + title;
+                title = "\"" + getMainPanel().getCurrentPhylogeny().getName() + "\" in " + title;
             }
-            showTextFrame( _mainpanel.getCurrentPhylogeny()
-                                   .toNewHampshire( false, getOptions().getNhConversionSupportValueStyle() ),
+            showTextFrame( _mainpanel.getCurrentPhylogeny().toNewHampshire( getOptions()
+                                   .getNhConversionSupportValueStyle() ),
                            title );
         }
     }
@@ -1203,168 +2071,65 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         if ( ( _mainpanel.getCurrentPhylogeny() != null ) && !_mainpanel.getCurrentPhylogeny().isEmpty() ) {
             String title = "phyloXML";
             if ( !ForesterUtil.isEmpty( _mainpanel.getCurrentPhylogeny().getName() ) ) {
-                title = _mainpanel.getCurrentPhylogeny().getName() + " " + title;
+                title = "\"" + getMainPanel().getCurrentPhylogeny().getName() + "\" in " + title;
             }
             showTextFrame( _mainpanel.getCurrentPhylogeny().toPhyloXML( 0 ), title );
         }
     }
 
-    private void annotateSequences() {
-        if ( getCurrentTreePanel() != null ) {
-            final Set<Long> nodes = getCurrentTreePanel().getFoundNodes();
-            if ( ( nodes == null ) || nodes.isEmpty() ) {
-                JOptionPane
-                        .showMessageDialog( this,
-                                            "Need to select nodes, either via direct selection or via the \"Search\" function",
-                                            "No nodes selected for annotation",
-                                            JOptionPane.ERROR_MESSAGE );
-                return;
-            }
-            final Phylogeny phy = getMainPanel().getCurrentPhylogeny();
-            if ( ( phy != null ) && !phy.isEmpty() ) {
-                final JTextField ref_field = new JTextField( 10 );
-                final JTextField desc_filed = new JTextField( 20 );
-                ref_field.setText( ForesterUtil.isEmpty( getPreviousNodeAnnotationReference() ) ? ""
-                        : getPreviousNodeAnnotationReference() );
-                final JPanel my_panel = new JPanel();
-                my_panel.add( new JLabel( "Reference " ) );
-                my_panel.add( ref_field );
-                my_panel.add( Box.createHorizontalStrut( 15 ) );
-                my_panel.add( new JLabel( "Description " ) );
-                my_panel.add( desc_filed );
-                final int result = JOptionPane.showConfirmDialog( null,
-                                                                  my_panel,
-                                                                  "Enter the sequence annotation(s) for the "
-                                                                          + nodes.size() + " selected nodes",
-                                                                  JOptionPane.OK_CANCEL_OPTION );
-                if ( result == JOptionPane.OK_OPTION ) {
-                    String ref = ref_field.getText();
-                    String desc = desc_filed.getText();
-                    if ( !ForesterUtil.isEmpty( ref ) ) {
-                        ref = ref.trim();
-                        ref = ref.replaceAll( "\\s+", " " );
-                        if ( ( ref.indexOf( ':' ) < 1 ) || ( ref.indexOf( ':' ) > ref.length() - 2 )
-                                || ( ref.length() < 3 ) ) {
-                            JOptionPane.showMessageDialog( this,
-                                                           "Reference needs to be in the form of \"GO:1234567\"",
-                                                           "Illegal Format for Annotation Reference",
-                                                           JOptionPane.ERROR_MESSAGE );
-                            return;
-                        }
-                    }
-                    if ( ref != null ) {
-                        setPreviousNodeAnnotationReference( ref );
-                    }
-                    if ( desc != null ) {
-                        desc = desc.trim();
-                        desc = desc.replaceAll( "\\s+", " " );
-                    }
-                    if ( !ForesterUtil.isEmpty( ref ) || !ForesterUtil.isEmpty( desc ) ) {
-                        for( final Long id : nodes ) {
-                            final PhylogenyNode n = phy.getNode( id );
-                            ForesterUtil.ensurePresenceOfSequence( n );
-                            final Annotation ann = ForesterUtil.isEmpty( ref ) ? new Annotation()
-                                    : new Annotation( ref );
-                            if ( !ForesterUtil.isEmpty( desc ) ) {
-                                ann.setDesc( desc );
-                            }
-                            n.getNodeData().getSequence().addAnnotation( ann );
-                        }
-                    }
-                    getMainPanel().getControlPanel().showAnnotations();
-                }
-            }
-        }
-    }
-
-    private void chooseFont() {
-        final FontChooser fc = new FontChooser();
-        fc.setFont( getMainPanel().getTreeFontSet().getLargeFont() );
-        fc.showDialog( this, "Select the Base Font" );
-        getMainPanel().getTreeFontSet().setBaseFont( fc.getFont() );
-    }
-
-    private void chooseMinimalConfidence() {
-        final String s = ( String ) JOptionPane
-                .showInputDialog( this,
-                                  "Please enter the minimum for confidence values to be displayed.\n"
-                                          + "[current value: " + getOptions().getMinConfidenceValue() + "]\n",
-                                  "Minimal Confidence Value",
-                                  JOptionPane.QUESTION_MESSAGE,
-                                  null,
-                                  null,
-                                  getOptions().getMinConfidenceValue() );
-        if ( !ForesterUtil.isEmpty( s ) ) {
-            boolean success = true;
-            double m = 0.0;
-            final String m_str = s.trim();
-            if ( !ForesterUtil.isEmpty( m_str ) ) {
-                try {
-                    m = Double.parseDouble( m_str );
+    private static void cycleNodeDataReturn( final Options op, final Configuration conf ) {
+        switch ( op.getExtDescNodeDataToReturn() ) {
+            case UNKNOWN:
+                op.setExtDescNodeDataToReturn( NodeDataField.DOMAINS_ALL );
+                break;
+            case DOMAINS_ALL:
+                op.setExtDescNodeDataToReturn( NodeDataField.DOMAINS_COLLAPSED_PER_PROTEIN );
+                break;
+            case DOMAINS_COLLAPSED_PER_PROTEIN:
+                op.setExtDescNodeDataToReturn( NodeDataField.SEQ_ANNOTATIONS );
+                break;
+            case SEQ_ANNOTATIONS:
+                op.setExtDescNodeDataToReturn( NodeDataField.GO_TERM_IDS );
+                break;
+            case GO_TERM_IDS:
+                op.setExtDescNodeDataToReturn( NodeDataField.SEQUENCE_MOL_SEQ_FASTA );
+                break;
+            case SEQUENCE_MOL_SEQ_FASTA:
+                if ( ( conf != null ) && ( conf.getExtDescNodeDataToReturn() != null )
+                        && ( conf.getExtDescNodeDataToReturn() != NodeDataField.DOMAINS_ALL )
+                        && ( conf.getExtDescNodeDataToReturn() != NodeDataField.DOMAINS_COLLAPSED_PER_PROTEIN )
+                        && ( conf.getExtDescNodeDataToReturn() != NodeDataField.SEQ_ANNOTATIONS )
+                        && ( conf.getExtDescNodeDataToReturn() != NodeDataField.GO_TERM_IDS )
+                        && ( conf.getExtDescNodeDataToReturn() != NodeDataField.SEQUENCE_MOL_SEQ_FASTA ) ) {
+                    op.setExtDescNodeDataToReturn( conf.getExtDescNodeDataToReturn() );
                 }
-                catch ( final Exception ex ) {
-                    success = false;
+                else {
+                    op.setExtDescNodeDataToReturn( NodeDataField.UNKNOWN );
                 }
-            }
-            else {
-                success = false;
-            }
-            if ( success && ( m >= 0.0 ) ) {
-                getOptions().setMinConfidenceValue( m );
-            }
-        }
-    }
-
-    private void doUpdateProcessMenu() {
-        if ( _process_pool.size() > 0 ) {
-            if ( _process_menu == null ) {
-                _process_menu = createMenu( "", getConfiguration() );
-                _process_menu.setForeground( Color.RED );
-            }
-            _process_menu.removeAll();
-            final String text = "processes running: " + _process_pool.size();
-            _process_menu.setText( text );
-            _jmenubar.add( _process_menu );
-            for( int i = 0; i < _process_pool.size(); ++i ) {
-                final ProcessRunning p = _process_pool.getProcessByIndex( i );
-                _process_menu.add( customizeJMenuItem( new JMenuItem( p.getName() + " [" + p.getStart() + "]" ) ) );
-            }
-        }
-        else {
-            if ( _process_menu != null ) {
-                _process_menu.removeAll();
-                _jmenubar.remove( _process_menu );
-            }
-        }
-        _jmenubar.validate();
-        _jmenubar.repaint();
-        repaint();
-    }
-
-    private String getPreviousNodeAnnotationReference() {
-        return _previous_node_annotation_ref;
-    }
-
-    private void removeBranchColors() {
-        if ( getMainPanel().getCurrentPhylogeny() != null ) {
-            AptxUtil.removeBranchColors( getMainPanel().getCurrentPhylogeny() );
+                break;
+            default:
+                op.setExtDescNodeDataToReturn( NodeDataField.UNKNOWN );
         }
     }
 
-    private void setPreviousNodeAnnotationReference( final String previous_node_annotation_ref ) {
-        _previous_node_annotation_ref = previous_node_annotation_ref;
-    }
-
     /**
      * Display the about box.
      */
-    static void about() {
-        final StringBuffer about = new StringBuffer( "Archaeopteryx\nVersion " + Constants.VERSION + "\n" );
-        about.append( "Copyright (C) 2013 Christian M. Zmasek\n" );
+    void about() {
+        final StringBuffer about = new StringBuffer( "Archaeopteryx\nVersion " + AptxConstants.VERSION + "\n" );
+        about.append( "Copyright (C) 2016 Christian M Zmasek\n" );
         about.append( "All Rights Reserved\n" );
         about.append( "License: GNU Lesser General Public License (LGPL)\n" );
-        about.append( "Last modified: " + Constants.PRG_DATE + "\n" );
+        about.append( "Last modified: " + AptxConstants.PRG_DATE + "\n" );
         about.append( "Based on: " + ForesterUtil.getForesterLibraryInformation() + "\n" );
+        
+        if  ( _configuration.isCouldReadConfigFile() ) {
+            about.append( "Using configuration file: " + _configuration.config_filename + "\n" );
+        }
+        else {
+            about.append( "Not using a configuration file\n" );
+        }
+        
         about.append( "phyloXML version : " + ForesterConstants.PHYLO_XML_VERSION + "\n" );
         about.append( "phyloXML location: " + ForesterConstants.PHYLO_XML_LOCATION + "\n" );
         if ( !ForesterUtil.isEmpty( ForesterUtil.JAVA_VERSION ) && !ForesterUtil.isEmpty( ForesterUtil.JAVA_VENDOR ) ) {
@@ -1381,11 +2146,13 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         about.append( "[free memory: " + free_memory + "MB, total memory: " + total_memory + "MB]\n" );
         about.append( "[locale: " + Locale.getDefault() + "]\n" );
         about.append( "References:\n" );
-        about.append( Constants.PHYLOXML_REFERENCE_SHORT + "\n" );
+        about.append( AptxConstants.PHYLOXML_REFERENCE_SHORT + "\n" );
         about.append( "For more information & download:\n" );
-        about.append( Constants.APTX_WEB_SITE + "\n" );
-        about.append( "Comments: " + Constants.AUTHOR_EMAIL );
-        JOptionPane.showMessageDialog( null, about, Constants.PRG_NAME, JOptionPane.PLAIN_MESSAGE );
+        about.append( AptxConstants.APTX_WEB_SITE + "\n" );
+        about.append( "Documentation:\n" );
+        about.append( AptxConstants.APTX_DOC_SITE + "\n" );
+        about.append( "Comments: " + AptxConstants.AUTHOR_EMAIL );
+        JOptionPane.showMessageDialog( null, about, AptxConstants.PRG_NAME, JOptionPane.PLAIN_MESSAGE );
     }
 
     static void chooseNodeSize( final Options options, final Component parent ) {
@@ -1448,7 +2215,7 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         return label;
     }
 
-    static void cycleNodeFill( final Options op, final TreePanel tree_panel ) {
+    static void cycleNodeFill( final Options op ) {
         switch ( op.getDefaultNodeFill() ) {
             case GRADIENT:
                 op.setDefaultNodeFill( NodeFill.SOLID );
@@ -1464,7 +2231,7 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
-    static void cycleNodeShape( final Options op, final TreePanel tree_panel ) {
+    static void cycleNodeShape( final Options op ) {
         switch ( op.getDefaultNodeShape() ) {
             case CIRCLE:
                 op.setDefaultNodeShape( NodeShape.RECTANGLE );
@@ -1499,6 +2266,90 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         }
     }
 
+    static void exceptionOccuredDuringSaveAs( final Exception e, final TreePanel tp, final Component comp ) {
+        try {
+            tp.setArrowCursor();
+        }
+        catch ( final Exception ex ) {
+            // Do nothing.
+        }
+        JOptionPane.showMessageDialog( comp, "Exception" + e, "Error during File|SaveAs", JOptionPane.ERROR_MESSAGE );
+    }
+
+    static void print( final TreePanel tp, final Options op, final Component c ) {
+        if ( ( tp == null ) || ( tp.getPhylogeny() == null ) || tp.getPhylogeny().isEmpty() ) {
+            return;
+        }
+        final String job_name = AptxConstants.PRG_NAME;
+        boolean error = false;
+        String printer_name = null;
+        try {
+            printer_name = Printer.print( tp, job_name );
+        }
+        catch ( final Exception e ) {
+            error = true;
+            JOptionPane.showMessageDialog( c, e.getMessage(), "Printing Error", JOptionPane.ERROR_MESSAGE );
+        }
+        if ( !error && ( printer_name != null ) ) {
+            String msg = "Printing data sent to printer";
+            if ( printer_name.length() > 1 ) {
+                msg += " [" + printer_name + "]";
+            }
+            JOptionPane.showMessageDialog( c, msg, "Printing...", JOptionPane.INFORMATION_MESSAGE );
+        }
+        if ( !op.isPrintUsingActualSize() ) {
+            tp.getControlPanel().showWhole();
+        }
+    }
+
+    static void printPhylogenyToPdf( final String file_name,
+                                     final Options opts,
+                                     final TreePanel tp,
+                                     final Component comp ) {
+       
+        String pdf_written_to = "";
+        boolean error = false;
+        try {
+            if ( opts.isPrintUsingActualSize() ) {
+                pdf_written_to = PdfExporter.writePhylogenyToPdf( file_name, tp, tp.getWidth() , tp.getHeight()  );
+            }
+            else {
+                // Never false.
+            }
+        }
+        catch ( final IOException e ) {
+            error = true;
+            JOptionPane.showMessageDialog( comp, e.getMessage(), "Error", JOptionPane.ERROR_MESSAGE );
+        }
+        if ( !error ) {
+            if ( !ForesterUtil.isEmpty( pdf_written_to ) ) {
+                JOptionPane.showMessageDialog( comp,
+                                               "Wrote PDF to: " + pdf_written_to,
+                                               "Information",
+                                               JOptionPane.INFORMATION_MESSAGE );
+            }
+            else {
+                JOptionPane.showMessageDialog( comp,
+                                               "There was an unknown problem when attempting to write to PDF file: \""
+                                                       + file_name + "\"",
+                                               "Error",
+                                               JOptionPane.ERROR_MESSAGE );
+            }
+        }
+        if ( !opts.isPrintUsingActualSize() ) {
+            tp.getControlPanel().showWhole();
+        }
+    }
+
+    static void setCycleDataReturnMenuItem( final JMenuItem mi, final Options options ) {
+        if ( ( options != null ) && ( options.getExtDescNodeDataToReturn() != null ) ) {
+            mi.setText( "Cycle Node Return Data... (current: " + options.getExtDescNodeDataToReturn().toString() + ")" );
+        }
+        else {
+            mi.setText( "Cycle Node Return Data..." );
+        }
+    }
+
     static void setCycleNodeFillMenuItem( final JMenuItem mi, final Options options ) {
         if ( ( options != null ) && ( options.getDefaultNodeFill() != null ) ) {
             mi.setText( "Cycle Node Shape Fill Type... (current: "
@@ -1530,15 +2381,20 @@ public abstract class MainFrame extends JFrame implements ActionListener {
 
     static void setTextColorChooseMenuItem( final JMenuItem mi, final TreePanel tree_panel ) {
         if ( ( tree_panel != null ) && ( tree_panel.getTreeColorSet() != null ) ) {
-            mi.setText( "Select Colors... (current: " + tree_panel.getTreeColorSet().getCurrentColorSchemeName() + ")" );
+            mi.setText( "Select Color Scheme... (current: " + tree_panel.getTreeColorSet().getCurrentColorSchemeName()
+                    + ")" );
         }
         else {
-            mi.setText( "Select Colors..." );
+            mi.setText( "Select Color Scheme..." );
         }
     }
 
     static void setTextForFontChooserMenuItem( final JMenuItem mi, final String font_desc ) {
-        mi.setText( "Select Font... (current: " + font_desc + ")" );
+        mi.setText( "Select Default Font... (current: " + font_desc + ")" );
+    }
+
+    static void setTextForPdfLineWidthChooserMenuItem( final JMenuItem mi, final Options o ) {
+        mi.setText( "Enter Default Line Width for PDF Export... (current: " + o.getPrintLineWidth() + ")" );
     }
 
     static void setTextMinSupportMenuItem( final JMenuItem mi, final Options options, final TreePanel current_tree_panel ) {
@@ -1558,87 +2414,443 @@ public abstract class MainFrame extends JFrame implements ActionListener {
         mi.setText( "Enter Default Node Shape Size... (current: " + options.getDefaultNodeShapeSize() + ")" );
     }
 
-    static void updateOptionsMenuDependingOnPhylogenyType( final MainPanel main_panel,
-                                                           final JCheckBoxMenuItem scale,
-                                                           final JCheckBoxMenuItem branch_lengths,
-                                                           final JRadioButtonMenuItem non_lined_up,
-                                                           final JRadioButtonMenuItem uniform_clado,
-                                                           final JRadioButtonMenuItem nonuniform_clado,
-                                                           final JCheckBoxMenuItem label_direction_cbmi ) {
-        final TreePanel tree_panel = main_panel.getCurrentTreePanel();
-        final ControlPanel control = main_panel.getControlPanel();
-        final Options options = main_panel.getOptions();
-        scale.setSelected( options.isShowScale() );
-        branch_lengths.setSelected( options.isShowBranchLengthValues() );
-        // non_lined_up.setSelected( options.isNonLinedUpCladogram() );
-        if ( ( tree_panel != null ) && ( !tree_panel.isPhyHasBranchLengths() ) ) {
-            scale.setSelected( false );
-            scale.setEnabled( false );
-            branch_lengths.setSelected( false );
-            branch_lengths.setEnabled( false );
-        }
-        else if ( ( tree_panel != null ) && !control.isDrawPhylogram() ) {
-            scale.setSelected( false );
-            scale.setEnabled( false );
-            branch_lengths.setEnabled( true );
+    static void updateScreenTextAntialias( final List<TreePanel> treepanels ) {
+        for( final TreePanel tree_panel : treepanels ) {
+            tree_panel.setTextAntialias();
         }
-        else {
-            scale.setEnabled( true );
-            branch_lengths.setEnabled( true );
+    }
+
+    static boolean writeAsNewHampshire( final TreePanel tp, final Options op, boolean exception, final File file ) {
+        try {
+            final PhylogenyWriter writer = new PhylogenyWriter();
+            writer.toNewHampshire( tp.getPhylogeny(), true, op.getNhConversionSupportValueStyle(), file );
         }
-        if ( ( tree_panel != null )
-                && ( ( tree_panel.getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.ROUNDED )
-                        && ( tree_panel.getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.EURO_STYLE ) && ( tree_panel
-                        .getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.RECTANGULAR ) ) ) {
-            branch_lengths.setSelected( false );
-            branch_lengths.setEnabled( false );
+        catch ( final Exception e ) {
+            exception = true;
+            exceptionOccuredDuringSaveAs( e, tp, tp );
         }
-        if ( tree_panel != null ) {
-            if ( ( tree_panel.getPhylogenyGraphicsType() == PHYLOGENY_GRAPHICS_TYPE.CIRCULAR )
-                    || ( tree_panel.getPhylogenyGraphicsType() == PHYLOGENY_GRAPHICS_TYPE.UNROOTED ) ) {
-                non_lined_up.setEnabled( false );
-                uniform_clado.setEnabled( false );
-                nonuniform_clado.setEnabled( false );
+        return exception;
+    }
+
+    static boolean writeAsNexus( final TreePanel tp, final Options op, boolean exception, final File file ) {
+        try {
+            final PhylogenyWriter writer = new PhylogenyWriter();
+            writer.toNexus( file, tp.getPhylogeny(), op.getNhConversionSupportValueStyle() );
+        }
+        catch ( final Exception e ) {
+            exception = true;
+            exceptionOccuredDuringSaveAs( e, tp, tp );
+        }
+        return exception;
+    }
+
+    static boolean writeAsPhyloXml( final TreePanel tp, final Options op, boolean exception, final File file ) {
+        try {
+            final PhylogenyWriter writer = new PhylogenyWriter();
+            writer.toPhyloXML( file, tp.getPhylogeny(), 0 );
+        }
+        catch ( final Exception e ) {
+            exception = true;
+            exceptionOccuredDuringSaveAs( e, tp, tp );
+        }
+        return exception;
+    }
+
+    static void writePhylogenyToGraphicsFile( final String file_name,
+                                              final GraphicsExportType type,
+                                              final MainPanel mp,
+                                              final Component comp,
+                                              final Container contentpane ) {
+        mp.getCurrentTreePanel().calcParametersForPainting( mp.getCurrentTreePanel().getWidth(),
+                                                            mp.getCurrentTreePanel().getHeight() );
+        String file_written_to = "";
+        boolean error = false;
+        try {
+            file_written_to = AptxUtil.writePhylogenyToGraphicsFile( file_name,
+                                                                     mp.getCurrentTreePanel().getWidth(),
+                                                                     mp.getCurrentTreePanel().getHeight(),
+                                                                     mp.getCurrentTreePanel(),
+                                                                     mp.getControlPanel(),
+                                                                     type,
+                                                                     mp.getOptions() );
+        }
+        catch ( final IOException e ) {
+            error = true;
+            JOptionPane.showMessageDialog( comp, e.getMessage(), "Error", JOptionPane.ERROR_MESSAGE );
+        }
+        if ( !error ) {
+            if ( ( file_written_to != null ) && ( file_written_to.length() > 0 ) ) {
+                JOptionPane.showMessageDialog( comp,
+                                               "Wrote image to: " + file_written_to,
+                                               "Graphics Export",
+                                               JOptionPane.INFORMATION_MESSAGE );
             }
             else {
-                non_lined_up.setEnabled( true );
-                uniform_clado.setEnabled( true );
-                nonuniform_clado.setEnabled( true );
+                JOptionPane.showMessageDialog( comp,
+                                               "There was an unknown problem when attempting to write to an image file: \""
+                                                       + file_name + "\"",
+                                               "Error",
+                                               JOptionPane.ERROR_MESSAGE );
             }
         }
+        contentpane.repaint();
+    }
+
+    static File writeToFile( final Phylogeny t,
+                             final MainPanel mp,
+                             final JFileChooser save_filechooser,
+                             final File current_dir,
+                             final Container contentpane,
+                             final Component comp ) {
+        File new_file = null;
+        if ( t == null ) {
+            return null;
+        }
+        String initial_filename = null;
+        if ( mp.getCurrentTreePanel().getTreeFile() != null ) {
+            try {
+                initial_filename = mp.getCurrentTreePanel().getTreeFile().getCanonicalPath();
+            }
+            catch ( final IOException e ) {
+                initial_filename = null;
+            }
+        }
+        if ( !ForesterUtil.isEmpty( initial_filename ) ) {
+            save_filechooser.setSelectedFile( new File( initial_filename ) );
+        }
         else {
-            if ( ( tree_panel != null )
-                    && ( ( tree_panel.getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.EURO_STYLE ) && ( tree_panel
-                            .getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.RECTANGULAR ) ) ) {
-                branch_lengths.setSelected( false );
-                branch_lengths.setEnabled( false );
+            save_filechooser.setSelectedFile( new File( "" ) );
+        }
+        final File my_dir = current_dir;
+        if ( my_dir != null ) {
+            save_filechooser.setCurrentDirectory( my_dir );
+        }
+        final int result = save_filechooser.showSaveDialog( contentpane );
+        final File file = save_filechooser.getSelectedFile();
+        new_file = save_filechooser.getCurrentDirectory();
+        boolean exception = false;
+        if ( ( file != null ) && ( result == JFileChooser.APPROVE_OPTION ) ) {
+            if ( file.exists() ) {
+                final int i = JOptionPane.showConfirmDialog( comp,
+                                                             file + " already exists.\nOverwrite?",
+                                                             "Overwrite?",
+                                                             JOptionPane.OK_CANCEL_OPTION,
+                                                             JOptionPane.QUESTION_MESSAGE );
+                if ( i != JOptionPane.OK_OPTION ) {
+                    return null;
+                }
+                else {
+                    final File to = new File( file.getAbsoluteFile().toString() + AptxConstants.BACKUP_FILE_SUFFIX );
+                    try {
+                        ForesterUtil.copyFile( file, to );
+                    }
+                    catch ( final Exception e ) {
+                        JOptionPane.showMessageDialog( comp,
+                                                       "Failed to create backup copy " + to,
+                                                       "Failed to Create Backup Copy",
+                                                       JOptionPane.WARNING_MESSAGE );
+                    }
+                    try {
+                        file.delete();
+                    }
+                    catch ( final Exception e ) {
+                        JOptionPane.showMessageDialog( comp,
+                                                       "Failed to delete: " + file,
+                                                       "Failed to Delete",
+                                                       JOptionPane.WARNING_MESSAGE );
+                    }
+                }
+            }
+            if ( save_filechooser.getFileFilter() == MainFrame.nhfilter ) {
+                exception = writeAsNewHampshire( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
             }
-            if ( ( tree_panel != null )
-                    && ( ( tree_panel.getPhylogenyGraphicsType() == PHYLOGENY_GRAPHICS_TYPE.CIRCULAR ) || ( tree_panel
-                            .getPhylogenyGraphicsType() == PHYLOGENY_GRAPHICS_TYPE.UNROOTED ) ) ) {
-                non_lined_up.setEnabled( false );
+            else if ( save_filechooser.getFileFilter() == MainFrame.xmlfilter ) {
+                exception = writeAsPhyloXml( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
             }
+            else if ( save_filechooser.getFileFilter() == MainFrame.nexusfilter ) {
+                exception = writeAsNexus( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
+            }
+            // "*.*":
             else {
-                // non_lined_up.setSelected( options.isNonLinedUpCladogram() );
-                non_lined_up.setEnabled( true );
+                final String file_name = file.getName().trim().toLowerCase();
+                if ( file_name.endsWith( ".nh" ) || file_name.endsWith( ".newick" ) || file_name.endsWith( ".phy" )
+                        || file_name.endsWith( ".tree" ) ) {
+                    exception = writeAsNewHampshire( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
+                }
+                else if ( file_name.endsWith( ".nex" ) || file_name.endsWith( ".nexus" ) ) {
+                    exception = writeAsNexus( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
+                }
+                // XML is default:
+                else {
+                    exception = writeAsPhyloXml( mp.getCurrentTreePanel(), mp.getOptions(), exception, file );
+                }
+            }
+            if ( !exception ) {
+                mp.setTitleOfSelectedTab( file.getName() );
+                mp.getCurrentTreePanel().setTreeFile( file );
+                mp.getCurrentTreePanel().setEdited( false );
             }
         }
-        label_direction_cbmi.setEnabled( true );
-        if ( tree_panel != null ) {
-            if ( ( tree_panel.getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.UNROOTED )
-                    && ( tree_panel.getPhylogenyGraphicsType() != PHYLOGENY_GRAPHICS_TYPE.CIRCULAR ) ) {
-                label_direction_cbmi.setEnabled( false );
+        return new_file;
+    }
+
+    static File writeToGraphicsFile( final Phylogeny t,
+                                     final GraphicsExportType type,
+                                     final MainPanel mp,
+                                     final JFileChooser writetographics_filechooser,
+                                     final Component component,
+                                     final Container contentpane,
+                                     final File current_dir ) {
+        File new_dir = null;
+        if ( ( t == null ) || t.isEmpty() ) {
+            return null;
+        }
+        String initial_filename = "";
+        if ( mp.getCurrentTreePanel().getTreeFile() != null ) {
+            initial_filename = mp.getCurrentTreePanel().getTreeFile().toString();
+        }
+        if ( initial_filename.indexOf( '.' ) > 0 ) {
+            initial_filename = initial_filename.substring( 0, initial_filename.lastIndexOf( '.' ) );
+        }
+        initial_filename = initial_filename + "." + type;
+        writetographics_filechooser.setSelectedFile( new File( initial_filename ) );
+        final File my_dir = current_dir;
+        if ( my_dir != null ) {
+            writetographics_filechooser.setCurrentDirectory( my_dir );
+        }
+        final int result = writetographics_filechooser.showSaveDialog( contentpane );
+        File file = writetographics_filechooser.getSelectedFile();
+        //setCurrentDir( writetographics_filechooser.getCurrentDirectory() );
+        new_dir = writetographics_filechooser.getCurrentDirectory();
+        if ( ( file != null ) && ( result == JFileChooser.APPROVE_OPTION ) ) {
+            if ( !file.toString().toLowerCase().endsWith( type.toString() ) ) {
+                file = new File( file.toString() + "." + type );
+            }
+            if ( file.exists() ) {
+                final int i = JOptionPane.showConfirmDialog( component,
+                                                             file + " already exists. Overwrite?",
+                                                             "Warning",
+                                                             JOptionPane.OK_CANCEL_OPTION,
+                                                             JOptionPane.WARNING_MESSAGE );
+                if ( i != JOptionPane.OK_OPTION ) {
+                    return null;
+                }
+                else {
+                    try {
+                        file.delete();
+                    }
+                    catch ( final Exception e ) {
+                        JOptionPane.showMessageDialog( component,
+                                                       "Failed to delete: " + file,
+                                                       "Error",
+                                                       JOptionPane.WARNING_MESSAGE );
+                    }
+                }
+            }
+            writePhylogenyToGraphicsFile( file.toString(), type, mp, component, contentpane );
+        }
+        return new_dir;
+    }
+
+    static File writeToPdf( final Phylogeny t,
+                            final MainPanel mp,
+                            final JFileChooser writetopdf_filechooser,
+                            final File curr_dir,
+                            final Container contentpane,
+                            final Component component ) {
+        if ( ( t == null ) || t.isEmpty() ) {
+            return null;
+        }
+        String initial_filename = "";
+        if ( mp.getCurrentTreePanel().getTreeFile() != null ) {
+            initial_filename = mp.getCurrentTreePanel().getTreeFile().toString();
+        }
+        if ( initial_filename.indexOf( '.' ) > 0 ) {
+            initial_filename = initial_filename.substring( 0, initial_filename.lastIndexOf( '.' ) );
+        }
+        initial_filename = initial_filename + ".pdf";
+        writetopdf_filechooser.setSelectedFile( new File( initial_filename ) );
+        final File my_dir = curr_dir;
+        if ( my_dir != null ) {
+            writetopdf_filechooser.setCurrentDirectory( my_dir );
+        }
+        final int result = writetopdf_filechooser.showSaveDialog( contentpane );
+        File file = writetopdf_filechooser.getSelectedFile();
+        // setCurrentDir( writetopdf_filechooser.getCurrentDirectory() );
+        final File new_current_dir = writetopdf_filechooser.getCurrentDirectory();
+        if ( ( file != null ) && ( result == JFileChooser.APPROVE_OPTION ) ) {
+            if ( !file.toString().toLowerCase().endsWith( ".pdf" ) ) {
+                file = new File( file.toString() + ".pdf" );
             }
-            if ( tree_panel.getPhylogenyGraphicsType() == PHYLOGENY_GRAPHICS_TYPE.CIRCULAR ) {
-                scale.setSelected( false );
-                scale.setEnabled( false );
+            if ( file.exists() ) {
+                final int i = JOptionPane.showConfirmDialog( component,
+                                                             file + " already exists. Overwrite?",
+                                                             "WARNING",
+                                                             JOptionPane.OK_CANCEL_OPTION,
+                                                             JOptionPane.WARNING_MESSAGE );
+                if ( i != JOptionPane.OK_OPTION ) {
+                    return null;
+                }
             }
+            printPhylogenyToPdf( file.toString(), mp.getOptions(), mp.getCurrentTreePanel(), component );
         }
+        return new_current_dir;
     }
 
-    static void updateScreenTextAntialias( final List<TreePanel> treepanels ) {
-        for( final TreePanel tree_panel : treepanels ) {
-            tree_panel.setTextAntialias();
-        }
+}
+
+class DefaultFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".nh" ) || file_name.endsWith( ".newick" ) || file_name.endsWith( ".phy" )
+                || file_name.endsWith( ".nwk" ) || file_name.endsWith( ".phb" ) || file_name.endsWith( ".ph" )
+                || file_name.endsWith( ".tr" ) || file_name.endsWith( ".dnd" ) || file_name.endsWith( ".tree" )
+                || file_name.endsWith( ".nhx" ) || file_name.endsWith( ".xml" ) || file_name.endsWith( ".phyloxml" )
+                || file_name.endsWith( "phylo.xml" ) || file_name.endsWith( ".pxml" ) || file_name.endsWith( ".nexus" )
+                || file_name.endsWith( ".nx" ) || file_name.endsWith( ".nex" ) || file_name.endsWith( ".tre" )
+                || file_name.endsWith( ".zip" ) || file_name.endsWith( ".tol" ) || file_name.endsWith( ".tolxml" )
+                || file_name.endsWith( ".con" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "All supported files (*.xml, *.phyloxml, *phylo.xml, *.nhx, *.nh, *.newick, *.nex, *.nexus, *.phy, *.tre, *.tree, *.tol, ...)";
+    }
+}
+
+class GraphicsFileFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".jpg" ) || file_name.endsWith( ".jpeg" ) || file_name.endsWith( ".png" )
+                || file_name.endsWith( ".gif" ) || file_name.endsWith( ".bmp" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "Image files (*.jpg, *.jpeg, *.png, *.gif, *.bmp)";
+    }
+}
+
+class MsaFileFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".msa" ) || file_name.endsWith( ".aln" ) || file_name.endsWith( ".fasta" )
+                || file_name.endsWith( ".fas" ) || file_name.endsWith( ".fa" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "Multiple sequence alignment files (*.msa, *.aln, *.fasta, *.fa, *.fas)";
+    }
+}
+
+class NexusFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".nex" ) || file_name.endsWith( ".nexus" ) || file_name.endsWith( ".nx" )
+                || file_name.endsWith( ".tre" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "Nexus files (*.nex, *.nexus, *.nx, *.tre)";
+    }
+} // NexusFilter
+
+class NHFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".nh" ) || file_name.endsWith( ".newick" ) || file_name.endsWith( ".phy" )
+                || file_name.endsWith( ".tr" ) || file_name.endsWith( ".tree" ) || file_name.endsWith( ".dnd" )
+                || file_name.endsWith( ".ph" ) || file_name.endsWith( ".phb" ) || file_name.endsWith( ".nwk" )
+                || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "New Hampshire - Newick files (*.nh, *.newick, *.phy, *.tree, *.dnd, *.tr, *.ph, *.phb, *.nwk)";
+    }
+} // NHFilter
+
+class NHXFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".nhx" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "NHX files (*.nhx) [deprecated]";
     }
 }
+
+class PdfFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        return f.getName().trim().toLowerCase().endsWith( ".pdf" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "PDF files (*.pdf)";
+    }
+} // PdfFilter
+
+class SequencesFileFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".fasta" ) || file_name.endsWith( ".fa" ) || file_name.endsWith( ".fas" )
+                || file_name.endsWith( ".seqs" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "Sequences files (*.fasta, *.fa, *.fas, *.seqs )";
+    }
+}
+
+class TolFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return ( file_name.endsWith( ".tol" ) || file_name.endsWith( ".tolxml" ) || file_name.endsWith( ".zip" ) || f
+                .isDirectory() ) && ( !file_name.endsWith( ".xml.zip" ) );
+    }
+
+    @Override
+    public String getDescription() {
+        return "Tree of Life files (*.tol, *.tolxml)";
+    }
+} // TolFilter
+
+class XMLFilter extends FileFilter {
+
+    @Override
+    public boolean accept( final File f ) {
+        final String file_name = f.getName().trim().toLowerCase();
+        return file_name.endsWith( ".xml" ) || file_name.endsWith( ".phyloxml" ) || file_name.endsWith( "phylo.xml" )
+                || file_name.endsWith( ".pxml" ) || file_name.endsWith( ".zip" ) || f.isDirectory();
+    }
+
+    @Override
+    public String getDescription() {
+        return "phyloXML files (*.xml, *.phyloxml, *phylo.xml, *.pxml, *.zip)";
+    }
+} // XMLFilter