Fixed issue with reading from TreeBase
[jalview.git] / forester / java / src / org / forester / test / Test.java
index 0701b66..3efa354 100644 (file)
@@ -2,8 +2,8 @@
 // FORESTER -- software libraries and applications
 // for evolutionary biology research and applications.
 //
-// Copyright (C) 2008-2009 Christian M. Zmasek
-// Copyright (C) 2008-2009 Burnham Institute for Medical Research
+// Copyright (C) 2014 Christian M. Zmasek
+// Copyright (C) 2014 Sanford-Burnham Medical Research Institute
 // All rights reserved
 //
 // This library is free software; you can redistribute it and/or
@@ -20,7 +20,6 @@
 // License along with this library; if not, write to the Free Software
 // Foundation, Inc., 51 Franklin Street, Fifth Floor, Boston, MA 02110-1301, USA
 //
-// Contact: phylosoft @ gmail . com
 // WWW: https://sites.google.com/site/cmzmasek/home/software/forester
 
 package org.forester.test;
@@ -29,6 +28,9 @@ import java.io.ByteArrayInputStream;
 import java.io.File;
 import java.io.FileInputStream;
 import java.io.IOException;
+import java.io.StringWriter;
+import java.io.Writer;
+import java.net.URL;
 import java.util.ArrayList;
 import java.util.Date;
 import java.util.HashSet;
@@ -38,8 +40,13 @@ import java.util.Locale;
 import java.util.Set;
 import java.util.SortedSet;
 
+import javax.net.ssl.HttpsURLConnection;
+import javax.net.ssl.SSLContext;
+
 import org.forester.application.support_transfer;
+import org.forester.archaeopteryx.AptxUtil;
 import org.forester.archaeopteryx.TreePanelUtil;
+import org.forester.archaeopteryx.webservices.WebserviceUtil;
 import org.forester.development.DevelopmentTools;
 import org.forester.evoinference.TestPhylogenyReconstruction;
 import org.forester.evoinference.matrix.character.CharacterStateMatrix;
@@ -60,8 +67,10 @@ import org.forester.io.parsers.util.ParserUtils;
 import org.forester.io.writers.PhylogenyWriter;
 import org.forester.io.writers.SequenceWriter;
 import org.forester.msa.BasicMsa;
+import org.forester.msa.DeleteableMsa;
 import org.forester.msa.Mafft;
 import org.forester.msa.Msa;
+import org.forester.msa.Msa.MSA_FORMAT;
 import org.forester.msa.MsaInferrer;
 import org.forester.msa.MsaMethods;
 import org.forester.pccx.TestPccx;
@@ -100,7 +109,7 @@ import org.forester.sdi.SDI;
 import org.forester.sdi.SDIR;
 import org.forester.sdi.TestGSDI;
 import org.forester.sequence.BasicSequence;
-import org.forester.sequence.Sequence;
+import org.forester.sequence.MolecularSequence;
 import org.forester.species.BasicSpecies;
 import org.forester.species.Species;
 import org.forester.surfacing.TestSurfacing;
@@ -119,38 +128,36 @@ import org.forester.util.SequenceAccessionTools;
 import org.forester.ws.seqdb.SequenceDatabaseEntry;
 import org.forester.ws.seqdb.SequenceDbWsTools;
 import org.forester.ws.seqdb.UniProtTaxonomy;
-import org.forester.ws.wabi.TxSearch;
-import org.forester.ws.wabi.TxSearch.RANKS;
-import org.forester.ws.wabi.TxSearch.TAX_NAME_CLASS;
-import org.forester.ws.wabi.TxSearch.TAX_RANK;
+
 
 @SuppressWarnings( "unused")
 public final class Test {
 
-    private final static boolean PERFORM_DB_TESTS          = true;
-    private final static double  ZERO_DIFF                 = 1.0E-9;
-    private final static String  PATH_TO_TEST_DATA         = System.getProperty( "user.dir" )
-                                                                   + ForesterUtil.getFileSeparator() + "test_data"
-                                                                   + ForesterUtil.getFileSeparator();
     private final static String  PATH_TO_RESOURCES         = System.getProperty( "user.dir" )
-                                                                   + ForesterUtil.getFileSeparator() + "resources"
-                                                                   + ForesterUtil.getFileSeparator();
-    private final static boolean USE_LOCAL_PHYLOXML_SCHEMA = true;
-    private static final String  PHYLOXML_REMOTE_XSD       = ForesterConstants.PHYLO_XML_LOCATION + "/"
-                                                                   + ForesterConstants.PHYLO_XML_VERSION + "/"
-                                                                   + ForesterConstants.PHYLO_XML_XSD;
+            + ForesterUtil.getFileSeparator() + "resources"
+            + ForesterUtil.getFileSeparator();
+    private final static String  PATH_TO_TEST_DATA         = System.getProperty( "user.dir" )
+            + ForesterUtil.getFileSeparator() + "test_data"
+            + ForesterUtil.getFileSeparator();
+    private final static boolean PERFORM_DB_TESTS          = true;
+    private static final boolean PERFORM_WEB_TREE_ACCESS   = true;
     private static final String  PHYLOXML_LOCAL_XSD        = PATH_TO_RESOURCES + "phyloxml_schema/"
-                                                                   + ForesterConstants.PHYLO_XML_VERSION + "/"
-                                                                   + ForesterConstants.PHYLO_XML_XSD;
+            + ForesterConstants.PHYLO_XML_VERSION + "/"
+            + ForesterConstants.PHYLO_XML_XSD;
+    private static final String  PHYLOXML_REMOTE_XSD       = ForesterConstants.PHYLO_XML_LOCATION + "/"
+            + ForesterConstants.PHYLO_XML_VERSION + "/"
+            + ForesterConstants.PHYLO_XML_XSD;
+    private final static boolean USE_LOCAL_PHYLOXML_SCHEMA = true;
+    private final static double  ZERO_DIFF                 = 1.0E-9;
 
-    public static boolean isEqual( final double a, final double b ) {
+    private static boolean isEqual( final double a, final double b ) {
         return ( ( Math.abs( a - b ) ) < Test.ZERO_DIFF );
     }
 
     public static void main( final String[] args ) {
         System.out.println( "[Java version: " + ForesterUtil.JAVA_VERSION + " " + ForesterUtil.JAVA_VENDOR + "]" );
         System.out.println( "[OS: " + ForesterUtil.OS_NAME + " " + ForesterUtil.OS_ARCH + " " + ForesterUtil.OS_VERSION
-                + "]" );
+                            + "]" );
         Locale.setDefault( Locale.US );
         System.out.println( "[Locale: " + Locale.getDefault() + "]" );
         int failed = 0;
@@ -174,6 +181,7 @@ public final class Test {
             System.exit( -1 );
         }
         final long start_time = new Date().getTime();
+        
         System.out.print( "Basic node methods: " );
         if ( Test.testBasicNodeMethods() ) {
             System.out.println( "OK." );
@@ -237,18 +245,6 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
-        if ( PERFORM_DB_TESTS ) {
-            System.out.print( "Ebi Entry Retrieval: " );
-            if ( Test.testEbiEntryRetrieval() ) {
-                System.out.println( "OK." );
-                succeeded++;
-            }
-            else {
-                System.out.println( "failed." );
-                failed++;
-            }
-        }
-        System.exit( 0 );
         System.out.print( "UniProtKB id extraction: " );
         if ( Test.testExtractUniProtKbProteinSeqIdentifier() ) {
             System.out.println( "OK." );
@@ -267,18 +263,6 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
-        if ( PERFORM_DB_TESTS ) {
-            System.out.print( "Sequence DB tools 2: " );
-            if ( testSequenceDbWsTools2() ) {
-                System.out.println( "OK." );
-                succeeded++;
-            }
-            else {
-                System.out.println( "failed." );
-                failed++;
-                System.exit( -1 );
-            }
-        }
         System.out.print( "Hmmscan output parser: " );
         if ( testHmmscanOutputParser() ) {
             System.out.println( "OK." );
@@ -288,6 +272,33 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
+        System.out.print( "Overlap removal: " );
+        if ( !org.forester.test.Test.testOverlapRemoval() ) {
+            System.out.println( "failed." );
+            failed++;
+        }
+        else {
+            succeeded++;
+        }
+        System.out.println( "OK." );
+        System.out.print( "Engulfing overlap removal: " );
+        if ( !Test.testEngulfingOverlapRemoval() ) {
+            System.out.println( "failed." );
+            failed++;
+        }
+        else {
+            succeeded++;
+        }
+        System.out.println( "OK." );
+        System.out.print( "Taxonomy data extraction: " );
+        if ( Test.testExtractTaxonomyDataFromNodeName() ) {
+            System.out.println( "OK." );
+            succeeded++;
+        }
+        else {
+            System.out.println( "failed." );
+            failed++;
+        }
         System.out.print( "Taxonomy code extraction: " );
         if ( Test.testExtractTaxonomyCodeFromNodeName() ) {
             System.out.println( "OK." );
@@ -486,6 +497,15 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
+        System.out.print( "Tree copy: " );
+        if ( Test.testTreeCopy() ) {
+            System.out.println( "OK." );
+            succeeded++;
+        }
+        else {
+            System.out.println( "failed." );
+            failed++;
+        }
         System.out.print( "Basic tree methods: " );
         if ( Test.testBasicTreeMethods() ) {
             System.out.println( "OK." );
@@ -849,29 +869,6 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
-        if ( PERFORM_DB_TESTS ) {
-            System.out.print( "Uniprot Entry Retrieval: " );
-            if ( Test.testUniprotEntryRetrieval() ) {
-                System.out.println( "OK." );
-                succeeded++;
-            }
-            else {
-                System.out.println( "failed." );
-                failed++;
-            }
-        }
-        if ( PERFORM_DB_TESTS ) {
-            System.out.print( "Uniprot Taxonomy Search: " );
-            if ( Test.testUniprotTaxonomySearch() ) {
-                System.out.println( "OK." );
-                succeeded++;
-            }
-            else {
-                System.out.println( "failed." );
-                failed++;
-            }
-        }
-        //----
         String path = "";
         final String os = ForesterUtil.OS_NAME.toLowerCase();
         if ( ( os.indexOf( "mac" ) >= 0 ) && ( os.indexOf( "os" ) > 0 ) ) {
@@ -881,13 +878,13 @@ public final class Test {
             path = "C:\\Program Files\\mafft-win\\mafft.bat";
         }
         else {
-            path = "/home/czmasek/bin/mafft";
-        }
-        if ( !MsaInferrer.isInstalled( path ) ) {
             path = "mafft";
-        }
-        if ( !MsaInferrer.isInstalled( path ) ) {
-            path = "/usr/local/bin/mafft";
+            if ( !MsaInferrer.isInstalled( path ) ) {
+                path = "/usr/bin/mafft";
+            }
+            if ( !MsaInferrer.isInstalled( path ) ) {
+                path = "/usr/local/bin/mafft";
+            }
         }
         if ( MsaInferrer.isInstalled( path ) ) {
             System.out.print( "MAFFT (external program): " );
@@ -899,7 +896,6 @@ public final class Test {
                 System.out.println( "failed [will not count towards failed tests]" );
             }
         }
-        //----
         System.out.print( "Next nodes with collapsed: " );
         if ( Test.testNextNodeWithCollapsing() ) {
             System.out.println( "OK." );
@@ -918,6 +914,128 @@ public final class Test {
             System.out.println( "failed." );
             failed++;
         }
+        System.out.print( "Deleteable MSA: " );
+        if ( Test.testDeleteableMsa() ) {
+            System.out.println( "OK." );
+            succeeded++;
+        }
+        else {
+            System.out.println( "failed." );
+            failed++;
+        }
+        System.out.print( "MSA entropy: " );
+        if ( Test.testMsaEntropy() ) {
+            System.out.println( "OK." );
+            succeeded++;
+        }
+        else {
+            System.out.println( "failed." );
+            failed++;
+        }
+        if ( PERFORM_DB_TESTS ) {
+            System.out.print( "Uniprot Entry Retrieval: " );
+            if ( Test.testUniprotEntryRetrieval() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "Ebi Entry Retrieval: " );
+            if ( Test.testEbiEntryRetrieval() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "Sequence DB tools 2: " );
+            if ( testSequenceDbWsTools2() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+                System.exit( -1 );
+            }
+            System.out.print( "Uniprot Taxonomy Search: " );
+            if ( Test.testUniprotTaxonomySearch() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+        }
+        if ( PERFORM_WEB_TREE_ACCESS ) {
+            System.out.print( "TreeBase acccess: " );
+            if ( Test.testTreeBaseReading() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "ToL access: " );
+            if ( Test.testToLReading() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "NHX parsing from URL: " );
+            if ( Test.testNHXparsingFromURL() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "NHX parsing from URL 2: " );
+            if ( Test.testNHXparsingFromURL2() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "phyloXML parsing from URL: " );
+            if ( Test.testPhyloXMLparsingFromURL() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "TreeFam access: " );
+            if ( Test.testTreeFamReading() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+            System.out.print( "Pfam tree access: " );
+            if ( Test.testPfamTreeReading() ) {
+                System.out.println( "OK." );
+                succeeded++;
+            }
+            else {
+                System.out.println( "failed." );
+                failed++;
+            }
+        }
         System.out.println();
         final Runtime rt = java.lang.Runtime.getRuntime();
         final long free_memory = rt.freeMemory() / 1000000;
@@ -936,98 +1054,95 @@ public final class Test {
         }
     }
 
-    private final static Phylogeny createPhylogeny( final String nhx ) throws IOException {
-        final Phylogeny p = ParserBasedPhylogenyFactory.getInstance().create( nhx, new NHXParser() )[ 0 ];
-        return p;
-    }
-
-    private final static Event getEvent( final Phylogeny p, final String n1, final String n2 ) {
-        return PhylogenyMethods.calculateLCA( p.getNode( n1 ), p.getNode( n2 ) ).getNodeData().getEvent();
-    }
-
-    private static boolean testAminoAcidSequence() {
+    private static boolean testEngulfingOverlapRemoval() {
         try {
-            final Sequence aa1 = BasicSequence.createAaSequence( "aa1", "aAklm-?xX*z$#" );
-            if ( aa1.getLength() != 13 ) {
-                return false;
-            }
-            if ( aa1.getResidueAt( 0 ) != 'A' ) {
-                return false;
-            }
-            if ( aa1.getResidueAt( 2 ) != 'K' ) {
-                return false;
-            }
-            if ( !new String( aa1.getMolecularSequence() ).equals( "AAKLM-XXX*ZXX" ) ) {
+            final Domain d0 = new BasicDomain( "d0", 0, 8, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d1 = new BasicDomain( "d1", 0, 1, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d2 = new BasicDomain( "d2", 0, 2, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d3 = new BasicDomain( "d3", 7, 8, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d4 = new BasicDomain( "d4", 7, 9, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d5 = new BasicDomain( "d4", 0, 9, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d6 = new BasicDomain( "d4", 4, 5, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final List<Boolean> covered = new ArrayList<Boolean>();
+            covered.add( true ); // 0
+            covered.add( false ); // 1
+            covered.add( true ); // 2
+            covered.add( false ); // 3
+            covered.add( true ); // 4
+            covered.add( true ); // 5
+            covered.add( false ); // 6
+            covered.add( true ); // 7
+            covered.add( true ); // 8
+            if ( ForesterUtil.isEngulfed( d0, covered ) ) {
                 return false;
             }
-            final Sequence aa2 = BasicSequence.createAaSequence( "aa3", "ARNDCQEGHILKMFPSTWYVX*-BZOJU" );
-            if ( !new String( aa2.getMolecularSequence() ).equals( "ARNDCQEGHILKMFPSTWYVX*-BZXXU" ) ) {
+            if ( ForesterUtil.isEngulfed( d1, covered ) ) {
                 return false;
             }
-            final Sequence dna1 = BasicSequence.createDnaSequence( "dna1", "ACGTUX*-?RYMKWSN" );
-            if ( !new String( dna1.getMolecularSequence() ).equals( "ACGTNN*-NRYMKWSN" ) ) {
+            if ( ForesterUtil.isEngulfed( d2, covered ) ) {
                 return false;
             }
-            final Sequence rna1 = BasicSequence.createRnaSequence( "rna1", "..ACGUTX*-?RYMKWSN" );
-            if ( !new String( rna1.getMolecularSequence() ).equals( "--ACGUNN*-NRYMKWSN" ) ) {
+            if ( !ForesterUtil.isEngulfed( d3, covered ) ) {
                 return false;
             }
-        }
-        catch ( final Exception e ) {
-            e.printStackTrace();
-            return false;
-        }
-        return true;
-    }
-
-    private static boolean testBasicDomain() {
-        try {
-            final Domain pd = new BasicDomain( "id", 23, 25, ( short ) 1, ( short ) 4, 0.1, -12 );
-            if ( !pd.getDomainId().equals( "id" ) ) {
+            if ( ForesterUtil.isEngulfed( d4, covered ) ) {
                 return false;
             }
-            if ( pd.getNumber() != 1 ) {
+            if ( ForesterUtil.isEngulfed( d5, covered ) ) {
                 return false;
             }
-            if ( pd.getTotalCount() != 4 ) {
+            if ( !ForesterUtil.isEngulfed( d6, covered ) ) {
                 return false;
             }
-            if ( !pd.equals( new BasicDomain( "id", 22, 111, ( short ) 1, ( short ) 4, 0.2, -12 ) ) ) {
+            final Domain a = new BasicDomain( "a", 0, 10, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain b = new BasicDomain( "b", 8, 20, ( short ) 1, ( short ) 1, 0.2, 1 );
+            final Domain c = new BasicDomain( "c", 15, 16, ( short ) 1, ( short ) 1, 0.3, 1 );
+            final Protein abc = new BasicProtein( "abc", "nemve", 0 );
+            abc.addProteinDomain( a );
+            abc.addProteinDomain( b );
+            abc.addProteinDomain( c );
+            final Protein abc_r1 = ForesterUtil.removeOverlappingDomains( 3, false, abc );
+            final Protein abc_r2 = ForesterUtil.removeOverlappingDomains( 3, true, abc );
+            if ( abc.getNumberOfProteinDomains() != 3 ) {
                 return false;
             }
-            final Domain a1 = new BasicDomain( "a", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
-            final BasicDomain a1_copy = new BasicDomain( "a", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
-            final BasicDomain a1_equal = new BasicDomain( "a", 524, 743994, ( short ) 1, ( short ) 300, 3.0005, 230 );
-            final BasicDomain a2 = new BasicDomain( "a", 1, 10, ( short ) 2, ( short ) 4, 0.1, -12 );
-            final BasicDomain a3 = new BasicDomain( "A", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
-            if ( !a1.equals( a1 ) ) {
+            if ( abc_r1.getNumberOfProteinDomains() != 3 ) {
                 return false;
             }
-            if ( !a1.equals( a1_copy ) ) {
+            if ( abc_r2.getNumberOfProteinDomains() != 2 ) {
                 return false;
             }
-            if ( !a1.equals( a1_equal ) ) {
+            if ( !abc_r2.getProteinDomain( 0 ).getDomainId().equals( "a" ) ) {
                 return false;
             }
-            if ( !a1.equals( a2 ) ) {
+            if ( !abc_r2.getProteinDomain( 1 ).getDomainId().equals( "b" ) ) {
                 return false;
             }
-            if ( a1.equals( a3 ) ) {
+            final Domain d = new BasicDomain( "d", 0, 10, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain e = new BasicDomain( "e", 8, 20, ( short ) 1, ( short ) 1, 0.3, 1 );
+            final Domain f = new BasicDomain( "f", 15, 16, ( short ) 1, ( short ) 1, 0.2, 1 );
+            final Protein def = new BasicProtein( "def", "nemve", 0 );
+            def.addProteinDomain( d );
+            def.addProteinDomain( e );
+            def.addProteinDomain( f );
+            final Protein def_r1 = ForesterUtil.removeOverlappingDomains( 5, false, def );
+            final Protein def_r2 = ForesterUtil.removeOverlappingDomains( 5, true, def );
+            if ( def.getNumberOfProteinDomains() != 3 ) {
                 return false;
             }
-            if ( a1.compareTo( a1 ) != 0 ) {
+            if ( def_r1.getNumberOfProteinDomains() != 3 ) {
                 return false;
             }
-            if ( a1.compareTo( a1_copy ) != 0 ) {
+            if ( def_r2.getNumberOfProteinDomains() != 3 ) {
                 return false;
             }
-            if ( a1.compareTo( a1_equal ) != 0 ) {
+            if ( !def_r2.getProteinDomain( 0 ).getDomainId().equals( "d" ) ) {
                 return false;
             }
-            if ( a1.compareTo( a2 ) != 0 ) {
+            if ( !def_r2.getProteinDomain( 1 ).getDomainId().equals( "f" ) ) {
                 return false;
             }
-            if ( a1.compareTo( a3 ) == 0 ) {
+            if ( !def_r2.getProteinDomain( 2 ).getDomainId().equals( "e" ) ) {
                 return false;
             }
         }
@@ -1038,22 +1153,626 @@ public final class Test {
         return true;
     }
 
-    private static boolean testBasicNodeMethods() {
+    private static final boolean testNHXparsingFromURL2() {
         try {
-            if ( PhylogenyNode.getNodeCount() != 0 ) {
+            final String s = "https://sites.google.com/site/cmzmasek/home/software/archaeopteryx/examples/simple/simple_1.nh";
+            final Phylogeny phys[] = AptxUtil.readPhylogeniesFromUrl( new URL( s ),
+                                                                      false,
+                                                                      false,
+                                                                      false,
+                                                                      TAXONOMY_EXTRACTION.NO,
+                                                                      false );
+            if ( ( phys == null ) || ( phys.length != 5 ) ) {
                 return false;
             }
-            final PhylogenyNode n1 = new PhylogenyNode();
-            final PhylogenyNode n2 = PhylogenyNode
-                    .createInstanceFromNhxString( "", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
-            final PhylogenyNode n3 = PhylogenyNode
-                    .createInstanceFromNhxString( "n3", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
-            final PhylogenyNode n4 = PhylogenyNode
-                    .createInstanceFromNhxString( "n4:0.01", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
-            if ( n1.isHasAssignedEvent() ) {
+            if ( !phys[ 0 ].toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                System.out.println( phys[ 0 ].toNewHampshire() );
                 return false;
             }
-            if ( PhylogenyNode.getNodeCount() != 4 ) {
+            if ( !phys[ 1 ].toNewHampshire().equals( "((1,2,3),(4,5,6),(7,8,9));" ) ) {
+                System.out.println( phys[ 1 ].toNewHampshire() );
+                return false;
+            }
+            final Phylogeny phys2[] = AptxUtil.readPhylogeniesFromUrl( new URL( s ),
+                                                                       false,
+                                                                       false,
+                                                                       false,
+                                                                       TAXONOMY_EXTRACTION.NO,
+                                                                       false );
+            if ( ( phys2 == null ) || ( phys2.length != 5 ) ) {
+                return false;
+            }
+            if ( !phys2[ 0 ].toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                System.out.println( phys2[ 0 ].toNewHampshire() );
+                return false;
+            }
+            if ( !phys2[ 1 ].toNewHampshire().equals( "((1,2,3),(4,5,6),(7,8,9));" ) ) {
+                System.out.println( phys2[ 1 ].toNewHampshire() );
+                return false;
+            }
+            final Phylogeny phys3[] = AptxUtil.readPhylogeniesFromUrl( new URL( "http://swisstree.vital-it.ch:80/"
+                    + "SwissTree/ST001/consensus_tree.nhx" ), false, false, false, TAXONOMY_EXTRACTION.NO, false );
+            if ( ( phys3 == null ) || ( phys3.length != 1 ) ) {
+                return false;
+            }
+            if ( !phys3[ 0 ]
+                    .toNewHampshire()
+                    .equals( "((((POP23a_CIOIN_ENSCING00000016202,POP23b_CIOIN_ENSCING00000016169),POP23_CIOSA_ENSCSAVG00000000248),((POP23a_BRAFL_C3ZMF1,POP23b_BRAFL_121417),(((POP3_ORYLA_ENSORLG00000019669,POP3_GASAC_ENSGACG00000014023,POP3_DANRE_Q6JWW1),(POP3_XENTR_B1H1F6,(POP3_CHICK_Q9DG25,(POP3_ORNAN_ENSOANG00000004179,POP3_MONDO_ENSMODG00000018033,((POP3_MOUSE_Q9ES81,POP3_RAT_Q3BCU3),POP3_RABIT_ENSOCUG00000025973,POP3_MACMU_ENSMMUG00000014473,POP3_HUMAN_Q9HBV1))))),(((POP2_GASAC_ENSGACG00000001420,POP2_ORYLA_ENSORLG00000008627,POP2_TAKRU_ENSTRUG00000015933),POP2_DANRE_ENSDARG00000069922),POP2_XENTR_ENSXETG00000018064,(((POP2_TAEGU_ENSTGUG00000013383,POP2_CHICK_Q6T9Z5),POP2_ANOCA_ENSACAG00000003557),((POP2_MACEU_ENSMEUG00000015825,POP2_MONDO_ENSMODG00000018205),((POP2_RABIT_ENSOCUG00000009515,(POP2_RAT_Q6P722,POP2_MOUSE_Q9ES82)),(POP2_MACMU_ENSMMUG00000000905,POP2_HUMAN_Q9HBU9)))))))),((POP1_CIOSA_ENSCSAVG00000000247,POP1_CIOIN_ENSCING00000000496),((POP1_DANRE_Q5PQZ7,(POP1_ORYLA_ENSORLG00000019663,POP1_GASAC_ENSGACG00000014015,POP1_TAKRU_ENSORLG00000019663)),(POP1_XENTR_B1H1G2,(POP1_ANOCA_ENSACAG00000003910,(POP1_TAEGU_ENSTGUG00000012218,POP1_CHICK_Q9DG23)),POP1_ORNAN_ENSOANG00000004180,POP1_MONDO_ENSMODG00000018034,(POP1_RABIT_ENSOCUG00000016944,(POP1_RAT_Q3BCU4,POP1_MOUSE_Q9ES83),(POP1_HUMAN_Q8NE79,POP1_MACMU_ENSMMUG00000014471))))));" ) ) {
+                System.out.println( phys3[ 0 ].toNewHampshire() );
+                return false;
+            }
+            final Phylogeny phys4[] = AptxUtil.readPhylogeniesFromUrl( new URL( "http://swisstree.vital-it.ch:80/"
+                    + "SwissTree/ST001/consensus_tree.nhx" ), false, false, false, TAXONOMY_EXTRACTION.NO, false );
+            if ( ( phys4 == null ) || ( phys4.length != 1 ) ) {
+                return false;
+            }
+            if ( !phys4[ 0 ]
+                    .toNewHampshire()
+                    .equals( "((((POP23a_CIOIN_ENSCING00000016202,POP23b_CIOIN_ENSCING00000016169),POP23_CIOSA_ENSCSAVG00000000248),((POP23a_BRAFL_C3ZMF1,POP23b_BRAFL_121417),(((POP3_ORYLA_ENSORLG00000019669,POP3_GASAC_ENSGACG00000014023,POP3_DANRE_Q6JWW1),(POP3_XENTR_B1H1F6,(POP3_CHICK_Q9DG25,(POP3_ORNAN_ENSOANG00000004179,POP3_MONDO_ENSMODG00000018033,((POP3_MOUSE_Q9ES81,POP3_RAT_Q3BCU3),POP3_RABIT_ENSOCUG00000025973,POP3_MACMU_ENSMMUG00000014473,POP3_HUMAN_Q9HBV1))))),(((POP2_GASAC_ENSGACG00000001420,POP2_ORYLA_ENSORLG00000008627,POP2_TAKRU_ENSTRUG00000015933),POP2_DANRE_ENSDARG00000069922),POP2_XENTR_ENSXETG00000018064,(((POP2_TAEGU_ENSTGUG00000013383,POP2_CHICK_Q6T9Z5),POP2_ANOCA_ENSACAG00000003557),((POP2_MACEU_ENSMEUG00000015825,POP2_MONDO_ENSMODG00000018205),((POP2_RABIT_ENSOCUG00000009515,(POP2_RAT_Q6P722,POP2_MOUSE_Q9ES82)),(POP2_MACMU_ENSMMUG00000000905,POP2_HUMAN_Q9HBU9)))))))),((POP1_CIOSA_ENSCSAVG00000000247,POP1_CIOIN_ENSCING00000000496),((POP1_DANRE_Q5PQZ7,(POP1_ORYLA_ENSORLG00000019663,POP1_GASAC_ENSGACG00000014015,POP1_TAKRU_ENSORLG00000019663)),(POP1_XENTR_B1H1G2,(POP1_ANOCA_ENSACAG00000003910,(POP1_TAEGU_ENSTGUG00000012218,POP1_CHICK_Q9DG23)),POP1_ORNAN_ENSOANG00000004180,POP1_MONDO_ENSMODG00000018034,(POP1_RABIT_ENSOCUG00000016944,(POP1_RAT_Q3BCU4,POP1_MOUSE_Q9ES83),(POP1_HUMAN_Q8NE79,POP1_MACMU_ENSMMUG00000014471))))));" ) ) {
+                System.out.println( phys4[ 0 ].toNewHampshire() );
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testNHXparsingFromURL() {
+        try {
+            final String s = "https://sites.google.com/site/cmzmasek/home/software/archaeopteryx/examples/simple/simple_1.nh";
+            final URL u = new URL( s );
+            final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
+            final Phylogeny[] phys = factory.create( u, new NHXParser() );
+            if ( ( phys == null ) || ( phys.length != 5 ) ) {
+                return false;
+            }
+            if ( !phys[ 0 ].toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                System.out.println( phys[ 0 ].toNewHampshire() );
+                return false;
+            }
+            if ( !phys[ 1 ].toNewHampshire().equals( "((1,2,3),(4,5,6),(7,8,9));" ) ) {
+                System.out.println( phys[ 1 ].toNewHampshire() );
+                return false;
+            }
+            final URL u2 = new URL( s );
+            final Phylogeny[] phys2 = factory.create( u2.openStream(), new NHXParser() );
+            if ( ( phys2 == null ) || ( phys2.length != 5 ) ) {
+                return false;
+            }
+            if ( !phys2[ 0 ].toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                System.out.println( phys2[ 0 ].toNewHampshire() );
+                return false;
+            }
+            final PhylogenyFactory factory2 = ParserBasedPhylogenyFactory.getInstance();
+            final NHXParser p = new NHXParser();
+            final URL u3 = new URL( s );
+            p.setSource( u3 );
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            if ( !p.next().toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                return false;
+            }
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            p.reset();
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            if ( !p.next().toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                return false;
+            }
+            if ( !p.next().toNewHampshire().equals( "((1,2,3),(4,5,6),(7,8,9));" ) ) {
+                return false;
+            }
+            p.reset();
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            if ( !p.next().toNewHampshire().equals( "((((A,B),C),D),(E,F));" ) ) {
+                return false;
+            }
+            if ( !p.next().toNewHampshire().equals( "((1,2,3),(4,5,6),(7,8,9));" ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            System.out.println( e.toString() );
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testOverlapRemoval() {
+        try {
+            final Domain d0 = new BasicDomain( "d0", ( short ) 2, ( short ) 5, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d1 = new BasicDomain( "d1", ( short ) 7, ( short ) 10, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d2 = new BasicDomain( "d2", ( short ) 0, ( short ) 20, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d3 = new BasicDomain( "d3", ( short ) 9, ( short ) 10, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final Domain d4 = new BasicDomain( "d4", ( short ) 7, ( short ) 8, ( short ) 1, ( short ) 1, 0.1, 1 );
+            final List<Boolean> covered = new ArrayList<Boolean>();
+            covered.add( true ); // 0
+            covered.add( false ); // 1
+            covered.add( true ); // 2
+            covered.add( false ); // 3
+            covered.add( true ); // 4
+            covered.add( true ); // 5
+            covered.add( false ); // 6
+            covered.add( true ); // 7
+            covered.add( true ); // 8
+            if ( ForesterUtil.calculateOverlap( d0, covered ) != 3 ) {
+                return false;
+            }
+            if ( ForesterUtil.calculateOverlap( d1, covered ) != 2 ) {
+                return false;
+            }
+            if ( ForesterUtil.calculateOverlap( d2, covered ) != 6 ) {
+                return false;
+            }
+            if ( ForesterUtil.calculateOverlap( d3, covered ) != 0 ) {
+                return false;
+            }
+            if ( ForesterUtil.calculateOverlap( d4, covered ) != 2 ) {
+                return false;
+            }
+            final Domain a = new BasicDomain( "a", ( short ) 2, ( short ) 5, ( short ) 1, ( short ) 1, 1, -1 );
+            final Domain b = new BasicDomain( "b", ( short ) 2, ( short ) 10, ( short ) 1, ( short ) 1, 0.1, -1 );
+            final Protein ab = new BasicProtein( "ab", "varanus", 0 );
+            ab.addProteinDomain( a );
+            ab.addProteinDomain( b );
+            final Protein ab_s0 = ForesterUtil.removeOverlappingDomains( 3, false, ab );
+            if ( ab.getNumberOfProteinDomains() != 2 ) {
+                return false;
+            }
+            if ( ab_s0.getNumberOfProteinDomains() != 1 ) {
+                return false;
+            }
+            if ( !ab_s0.getProteinDomain( 0 ).getDomainId().equals( "b" ) ) {
+                return false;
+            }
+            final Protein ab_s1 = ForesterUtil.removeOverlappingDomains( 4, false, ab );
+            if ( ab.getNumberOfProteinDomains() != 2 ) {
+                return false;
+            }
+            if ( ab_s1.getNumberOfProteinDomains() != 2 ) {
+                return false;
+            }
+            final Domain c = new BasicDomain( "c", ( short ) 20000, ( short ) 20500, ( short ) 1, ( short ) 1, 10, 1 );
+            final Domain d = new BasicDomain( "d",
+                                              ( short ) 10000,
+                                              ( short ) 10500,
+                                              ( short ) 1,
+                                              ( short ) 1,
+                                              0.0000001,
+                                              1 );
+            final Domain e = new BasicDomain( "e", ( short ) 5000, ( short ) 5500, ( short ) 1, ( short ) 1, 0.0001, 1 );
+            final Protein cde = new BasicProtein( "cde", "varanus", 0 );
+            cde.addProteinDomain( c );
+            cde.addProteinDomain( d );
+            cde.addProteinDomain( e );
+            final Protein cde_s0 = ForesterUtil.removeOverlappingDomains( 0, false, cde );
+            if ( cde.getNumberOfProteinDomains() != 3 ) {
+                return false;
+            }
+            if ( cde_s0.getNumberOfProteinDomains() != 3 ) {
+                return false;
+            }
+            final Domain f = new BasicDomain( "f", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 10, 1 );
+            final Domain g = new BasicDomain( "g", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 0.01, 1 );
+            final Domain h = new BasicDomain( "h", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 0.0001, 1 );
+            final Domain i = new BasicDomain( "i", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 0.5, 1 );
+            final Domain i2 = new BasicDomain( "i", ( short ) 5, ( short ) 30, ( short ) 1, ( short ) 1, 0.5, 10 );
+            final Protein fghi = new BasicProtein( "fghi", "varanus", 0 );
+            fghi.addProteinDomain( f );
+            fghi.addProteinDomain( g );
+            fghi.addProteinDomain( h );
+            fghi.addProteinDomain( i );
+            fghi.addProteinDomain( i );
+            fghi.addProteinDomain( i );
+            fghi.addProteinDomain( i2 );
+            final Protein fghi_s0 = ForesterUtil.removeOverlappingDomains( 10, false, fghi );
+            if ( fghi.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            if ( fghi_s0.getNumberOfProteinDomains() != 1 ) {
+                return false;
+            }
+            if ( !fghi_s0.getProteinDomain( 0 ).getDomainId().equals( "h" ) ) {
+                return false;
+            }
+            final Protein fghi_s1 = ForesterUtil.removeOverlappingDomains( 11, false, fghi );
+            if ( fghi.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            if ( fghi_s1.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            final Domain j = new BasicDomain( "j", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 10, 1 );
+            final Domain k = new BasicDomain( "k", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 0.01, 1 );
+            final Domain l = new BasicDomain( "l", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 1, 0.0001, 1 );
+            final Domain m = new BasicDomain( "m", ( short ) 10, ( short ) 20, ( short ) 1, ( short ) 4, 0.5, 1 );
+            final Domain m0 = new BasicDomain( "m", ( short ) 10, ( short ) 20, ( short ) 2, ( short ) 4, 0.5, 1 );
+            final Domain m1 = new BasicDomain( "m", ( short ) 10, ( short ) 20, ( short ) 3, ( short ) 4, 0.5, 1 );
+            final Domain m2 = new BasicDomain( "m", ( short ) 5, ( short ) 30, ( short ) 4, ( short ) 4, 0.5, 10 );
+            final Protein jklm = new BasicProtein( "jklm", "varanus", 0 );
+            jklm.addProteinDomain( j );
+            jklm.addProteinDomain( k );
+            jklm.addProteinDomain( l );
+            jklm.addProteinDomain( m );
+            jklm.addProteinDomain( m0 );
+            jklm.addProteinDomain( m1 );
+            jklm.addProteinDomain( m2 );
+            final Protein jklm_s0 = ForesterUtil.removeOverlappingDomains( 10, false, jklm );
+            if ( jklm.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            if ( jklm_s0.getNumberOfProteinDomains() != 1 ) {
+                return false;
+            }
+            if ( !jklm_s0.getProteinDomain( 0 ).getDomainId().equals( "l" ) ) {
+                return false;
+            }
+            final Protein jklm_s1 = ForesterUtil.removeOverlappingDomains( 11, false, jklm );
+            if ( jklm.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            if ( jklm_s1.getNumberOfProteinDomains() != 7 ) {
+                return false;
+            }
+            final Domain only = new BasicDomain( "only", ( short ) 5, ( short ) 30, ( short ) 4, ( short ) 4, 0.5, 10 );
+            final Protein od = new BasicProtein( "od", "varanus", 0 );
+            od.addProteinDomain( only );
+            final Protein od_s0 = ForesterUtil.removeOverlappingDomains( 0, false, od );
+            if ( od.getNumberOfProteinDomains() != 1 ) {
+                return false;
+            }
+            if ( od_s0.getNumberOfProteinDomains() != 1 ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testPfamTreeReading() {
+        try {
+            final URL u = new URL( WebserviceUtil.PFAM_SERVER + "/family/PF" + "01849" + "/tree/download" );
+            final NHXParser parser = new NHXParser();
+            parser.setTaxonomyExtraction( NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
+            parser.setReplaceUnderscores( false );
+            parser.setGuessRootedness( true );
+            final Phylogeny[] phys = ForesterUtil.readPhylogeniesFromUrl( u, parser);
+            if ( ( phys == null ) || ( phys.length != 1 ) ) {
+                return false;
+            }
+            if ( phys[ 0 ].getNumberOfExternalNodes() < 10 ) {
+                return false;
+            }
+            final Phylogeny[] phys2 = ForesterUtil.readPhylogeniesFromUrl( u, parser);
+            if ( ( phys2 == null ) || ( phys2.length != 1 ) ) {
+                return false;
+            }
+            if ( phys2[ 0 ].getNumberOfExternalNodes() != phys[ 0 ].getNumberOfExternalNodes() ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testPhyloXMLparsingFromURL() {
+        try {
+            final String s = "https://sites.google.com/site/cmzmasek/home/software/archaeopteryx/examples/archaeopteryx_a/apaf_bcl2.xml";
+            final URL u = new URL( s );
+            final Phylogeny[] phys = ForesterUtil.readPhylogeniesFromUrl( u, PhyloXmlParser.createPhyloXmlParser() );
+            
+            if ( ( phys == null ) || ( phys.length != 2 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys2 = ForesterUtil.readPhylogeniesFromUrl( u, PhyloXmlParser.createPhyloXmlParser() );
+            
+            if ( ( phys2 == null ) || ( phys2.length != 2 ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testToLReading() {
+        try {
+            final URL u = new URL( WebserviceUtil.TOL_URL_BASE + "15079" );
+            final Phylogeny[] phys = ForesterUtil.readPhylogeniesFromUrl( u, new TolParser() );
+            if ( ( phys == null ) || ( phys.length != 1 ) ) {
+                return false;
+            }
+            if ( !phys[ 0 ].getRoot().getNodeData().getTaxonomy().getIdentifier().getValue().equals( "15079" ) ) {
+                return false;
+            }
+            if ( !phys[ 0 ].getRoot().getNodeData().getTaxonomy().getScientificName().equals( "Protacanthopterygii" ) ) {
+                return false;
+            }
+            if ( phys[ 0 ].getNumberOfExternalNodes() < 5 ) {
+                return false;
+            }
+            //
+            final URL u2 = new URL( WebserviceUtil.TOL_URL_BASE + "17706" );
+            final Phylogeny[] phys2 = ForesterUtil.readPhylogeniesFromUrl( u2, new TolParser() );
+            if ( ( phys2 == null ) || ( phys2.length != 1 ) ) {
+                return false;
+            }
+            if ( !phys2[ 0 ].getRoot().getNodeData().getTaxonomy().getIdentifier().getValue().equals( "17706" ) ) {
+                return false;
+            }
+            if ( phys2[ 0 ].getNumberOfExternalNodes() < 5 ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testTreeBaseReading() {
+        try {
+            final URL u = new URL( WebserviceUtil.TREEBASE_PHYLOWS_TREE_URL_BASE + "72557?format=nexus" );  
+            final NexusPhylogeniesParser parser = new NexusPhylogeniesParser();
+            parser.setReplaceUnderscores( true );
+            final Phylogeny[] phys = ForesterUtil.readPhylogeniesFromUrl( u, parser );
+            if ( ( phys == null ) || ( phys.length != 1 ) ) {
+                return false;
+            }
+            final URL u_1 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_TREE_URL_BASE + "2406?format=nexus" );  
+            final NexusPhylogeniesParser parser_1 = new NexusPhylogeniesParser();
+            final Phylogeny[] phys_1 = ForesterUtil.readPhylogeniesFromUrl( u_1, parser_1 );
+            if ( ( phys_1 == null ) || ( phys_1.length != 1 ) ) {
+                return false;
+            }
+            final URL u_2 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_TREE_URL_BASE + "422?format=nexus" );  
+            final NexusPhylogeniesParser parser_2 = new NexusPhylogeniesParser();
+            final Phylogeny[] phys_2 = ForesterUtil.readPhylogeniesFromUrl( u_2, parser_2 );
+            if ( ( phys_2 == null ) || ( phys_2.length != 1 ) ) {
+                return false;
+            }
+            final URL u_3 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_TREE_URL_BASE + "2654?format=nexus" );  
+            final NexusPhylogeniesParser parser_3 = new NexusPhylogeniesParser();
+            final Phylogeny[] phys_3 = ForesterUtil.readPhylogeniesFromUrl( u_3, parser_3 );
+             if ( ( phys_3 == null ) || ( phys_3.length != 1 ) ) {
+                return false;
+            }
+            final URL u_4 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_TREE_URL_BASE + "825?format=nexus" );  
+            final NexusPhylogeniesParser parser_4 = new NexusPhylogeniesParser();
+            final Phylogeny[] phys_4 = ForesterUtil.readPhylogeniesFromUrl( u_4, parser_4 );
+             if ( ( phys_4 == null ) || ( phys_4.length != 1 ) ) {
+                return false;
+            }
+            final URL u2 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "15613?format=nexus" );
+            final NexusPhylogeniesParser parser2 = new NexusPhylogeniesParser();
+            parser2.setReplaceUnderscores( true );
+            final Phylogeny[] phys2 = ForesterUtil.readPhylogeniesFromUrl( u2, parser2 );
+            if ( ( phys2 == null ) || ( phys2.length != 9 ) ) {
+                return false;
+            }
+            final URL u3 = new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "14909?format=nexus" );
+            final NexusPhylogeniesParser parser3 = new NexusPhylogeniesParser();
+            final Phylogeny[] phys3 = ForesterUtil.readPhylogeniesFromUrl( u3, parser3 );
+            if ( ( phys3 == null ) || ( phys3.length != 2 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys4 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "14525?format=nexus" ),
+                    new NexusPhylogeniesParser() );
+            if ( ( phys4 == null ) || ( phys4.length != 1 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys5 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "15632?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys5 == null ) || ( phys5.length != 1 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys6 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "10190?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys6 == null ) || ( phys6.length != 1 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys7 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "13246?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys7 == null ) || ( phys7.length != 2 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys8 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "11662?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys8 == null ) || ( phys8.length != 2 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys9 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "562?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys9 == null ) || ( phys9.length != 4 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys16424 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "16424?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys16424 == null ) || ( phys16424.length != 1 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys17878 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "17878?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys17878 == null ) || ( phys17878.length != 17 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys18804 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "18804?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys18804 == null ) || ( phys18804.length != 2 ) ) {
+                return false;
+            }
+            final Phylogeny[] phys346 = ForesterUtil.readPhylogeniesFromUrl( new URL( WebserviceUtil.TREEBASE_PHYLOWS_STUDY_URL_BASE + "346?format=nexus" ) ,
+                    new NexusPhylogeniesParser() );
+            if ( ( phys346 == null ) || ( phys346.length != 1 ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static final boolean testTreeFamReading() {
+        try {
+            final URL u = new URL( WebserviceUtil.TREE_FAM_URL_BASE + "101004" + "/tree/newick" );
+            final NHXParser parser = new NHXParser();
+            parser.setTaxonomyExtraction( NHXParser.TAXONOMY_EXTRACTION.NO );
+            parser.setReplaceUnderscores( false );
+            parser.setGuessRootedness( true );
+            final Phylogeny[] phys = ForesterUtil.readPhylogeniesFromUrl( u, parser );
+            if ( ( phys == null ) || ( phys.length != 1 ) ) {
+                return false;
+            }
+            if ( phys[ 0 ].getNumberOfExternalNodes() < 10 ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private final static Phylogeny createPhylogeny( final String nhx ) throws IOException {
+        final Phylogeny p = ParserBasedPhylogenyFactory.getInstance().create( nhx, new NHXParser() )[ 0 ];
+        return p;
+    }
+
+    private final static Event getEvent( final Phylogeny p, final String n1, final String n2 ) {
+        return PhylogenyMethods.calculateLCA( p.getNode( n1 ), p.getNode( n2 ) ).getNodeData().getEvent();
+    }
+
+    private static boolean testAminoAcidSequence() {
+        try {
+            final MolecularSequence aa1 = BasicSequence.createAaSequence( "aa1", "aAklm-?xX*z$#" );
+            if ( aa1.getLength() != 13 ) {
+                return false;
+            }
+            if ( aa1.getResidueAt( 0 ) != 'A' ) {
+                return false;
+            }
+            if ( aa1.getResidueAt( 2 ) != 'K' ) {
+                return false;
+            }
+            if ( !new String( aa1.getMolecularSequence() ).equals( "AAKLM-XXX*ZXX" ) ) {
+                return false;
+            }
+            final MolecularSequence aa2 = BasicSequence.createAaSequence( "aa3", "ARNDCQEGHILKMFPSTWYVX*-BZOJU" );
+            if ( !new String( aa2.getMolecularSequence() ).equals( "ARNDCQEGHILKMFPSTWYVX*-BZOXU" ) ) {
+                return false;
+            }
+            final MolecularSequence dna1 = BasicSequence.createDnaSequence( "dna1", "ACGTUX*-?RYMKWSN" );
+            if ( !new String( dna1.getMolecularSequence() ).equals( "ACGTNN*-NRYMKWSN" ) ) {
+                return false;
+            }
+            final MolecularSequence rna1 = BasicSequence.createRnaSequence( "rna1", "..ACGUTX*-?RYMKWSN" );
+            if ( !new String( rna1.getMolecularSequence() ).equals( "--ACGUNN*-NRYMKWSN" ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testBasicDomain() {
+        try {
+            final Domain pd = new BasicDomain( "id", 23, 25, ( short ) 1, ( short ) 4, 0.1, -12 );
+            if ( !pd.getDomainId().equals( "id" ) ) {
+                return false;
+            }
+            if ( pd.getNumber() != 1 ) {
+                return false;
+            }
+            if ( pd.getTotalCount() != 4 ) {
+                return false;
+            }
+            if ( !pd.equals( new BasicDomain( "id", 22, 111, ( short ) 1, ( short ) 4, 0.2, -12 ) ) ) {
+                return false;
+            }
+            final Domain a1 = new BasicDomain( "a", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
+            final BasicDomain a1_copy = new BasicDomain( "a", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
+            final BasicDomain a1_equal = new BasicDomain( "a", 524, 743994, ( short ) 1, ( short ) 300, 3.0005, 230 );
+            final BasicDomain a2 = new BasicDomain( "a", 1, 10, ( short ) 2, ( short ) 4, 0.1, -12 );
+            final BasicDomain a3 = new BasicDomain( "A", 1, 10, ( short ) 1, ( short ) 4, 0.1, -12 );
+            if ( !a1.equals( a1 ) ) {
+                return false;
+            }
+            if ( !a1.equals( a1_copy ) ) {
+                return false;
+            }
+            if ( !a1.equals( a1_equal ) ) {
+                return false;
+            }
+            if ( !a1.equals( a2 ) ) {
+                return false;
+            }
+            if ( a1.equals( a3 ) ) {
+                return false;
+            }
+            if ( a1.compareTo( a1 ) != 0 ) {
+                return false;
+            }
+            if ( a1.compareTo( a1_copy ) != 0 ) {
+                return false;
+            }
+            if ( a1.compareTo( a1_equal ) != 0 ) {
+                return false;
+            }
+            if ( a1.compareTo( a2 ) != 0 ) {
+                return false;
+            }
+            if ( a1.compareTo( a3 ) == 0 ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testBasicNodeMethods() {
+        try {
+            if ( PhylogenyNode.getNodeCount() != 0 ) {
+                return false;
+            }
+            final PhylogenyNode n1 = new PhylogenyNode();
+            final PhylogenyNode n2 = PhylogenyNode
+                    .createInstanceFromNhxString( "", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
+            final PhylogenyNode n3 = PhylogenyNode
+                    .createInstanceFromNhxString( "n3", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
+            final PhylogenyNode n4 = PhylogenyNode
+                    .createInstanceFromNhxString( "n4:0.01", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_STRICT );
+            if ( n1.isHasAssignedEvent() ) {
+                return false;
+            }
+            if ( PhylogenyNode.getNodeCount() != 4 ) {
                 return false;
             }
             if ( n3.getIndicator() != 0 ) {
@@ -1082,7 +1801,7 @@ public final class Test {
     private static boolean testBasicPhyloXMLparsing() {
         try {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            final PhyloXmlParser xml_parser = new PhyloXmlParser();
+            final PhyloXmlParser xml_parser = PhyloXmlParser.createPhyloXmlParser();
             final Phylogeny[] phylogenies_0 = factory.create( Test.PATH_TO_TEST_DATA + "phyloxml_test_t1.xml",
                                                               xml_parser );
             if ( xml_parser.getErrorCount() > 0 ) {
@@ -1158,6 +1877,21 @@ public final class Test {
             if ( !t3.getIdentifier().getProvider().equals( "treebank" ) ) {
                 return false;
             }
+            if ( !t3.getNode( "root node" ).isDuplication() ) {
+                return false;
+            }
+            if ( !t3.getNode( "node a" ).isDuplication() ) {
+                return false;
+            }
+            if ( t3.getNode( "node a" ).isSpeciation() ) {
+                return false;
+            }
+            if ( t3.getNode( "node bc" ).isDuplication() ) {
+                return false;
+            }
+            if ( !t3.getNode( "node bc" ).isSpeciation() ) {
+                return false;
+            }
             if ( !t3.getNode( "root node" ).getNodeData().getSequence().getType().equals( "protein" ) ) {
                 return false;
             }
@@ -1275,7 +2009,7 @@ public final class Test {
     private static boolean testBasicPhyloXMLparsingRoundtrip() {
         try {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            final PhyloXmlParser xml_parser = new PhyloXmlParser();
+            final PhyloXmlParser xml_parser = PhyloXmlParser.createPhyloXmlParser();
             if ( USE_LOCAL_PHYLOXML_SCHEMA ) {
                 xml_parser.setValidateAgainstSchema( PHYLOXML_LOCAL_XSD );
             }
@@ -1485,7 +2219,7 @@ public final class Test {
                 return false;
             }
             if ( t3_rt.getNode( "node bc" ).getNodeData().getSequence().getDomainArchitecture().getDomain( 0 )
-                    .getConfidence() != 2144 ) {
+                    .getConfidence() != 0 ) {
                 return false;
             }
             if ( !t3_rt.getNode( "node bc" ).getNodeData().getSequence().getDomainArchitecture().getDomain( 0 ).getId()
@@ -1566,7 +2300,6 @@ public final class Test {
             if ( !t3_rt.getNode( "node b" ).getNodeData().getBinaryCharacters().getType().equals( "characters" ) ) {
                 return false;
             }
-            //
             if ( !t3_rt.getNode( "node ba" ).getNodeData().getDate().getDesc().equals( "Silurian" ) ) {
                 return false;
             }
@@ -1627,7 +2360,7 @@ public final class Test {
                 // Do nothing -- means were not running from jar.
             }
             if ( xml_parser == null ) {
-                xml_parser = new PhyloXmlParser();
+                xml_parser = PhyloXmlParser.createPhyloXmlParser();
                 if ( USE_LOCAL_PHYLOXML_SCHEMA ) {
                     xml_parser.setValidateAgainstSchema( PHYLOXML_LOCAL_XSD );
                 }
@@ -2303,10 +3036,6 @@ public final class Test {
     private static boolean testBasicTreeMethods() {
         try {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            final Phylogeny t1 = factory.create();
-            if ( !t1.isEmpty() ) {
-                return false;
-            }
             final Phylogeny t2 = factory.create( "((A:1,B:2)AB:1,(C:3,D:5)CD:3)ABCD:0.5", new NHXParser() )[ 0 ];
             if ( t2.getNumberOfExternalNodes() != 4 ) {
                 return false;
@@ -2444,7 +3173,6 @@ public final class Test {
             if ( !isEqual( t_bx.getNode( "acd" ).getBranchData().getConfidence( 0 ).getValue(), 1 ) ) {
                 return false;
             }
-            //
             final Phylogeny[] t2 = factory
                     .create( "((((a,b),c),d),e);(((a,b),c),(d,e));(((((a,b),c),d),e),f);((((a,b),c),(d,e)),f);(((a,b),c),d,e);((a,b,c),d,e);",
                              new NHXParser() );
@@ -2454,7 +3182,6 @@ public final class Test {
             for( final Phylogeny target : t2 ) {
                 ConfidenceAssessor.evaluate( "bootstrap", ev2, target, false, 1 );
             }
-            //
             final Phylogeny t4 = factory.create( "((((((A,B)ab,C)abc,D)abcd,E)abcde,F)abcdef,G)abcdefg",
                                                  new NHXParser() )[ 0 ];
             final Phylogeny[] ev4 = factory.create( "(((A,B),C),(X,Y));((F,G),((A,B,C),(D,E)))", new NHXParser() );
@@ -2963,7 +3690,7 @@ public final class Test {
             if ( t4.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            String s = w.toNewHampshire( t4, false, true ).toString();
+            String s = w.toNewHampshire( t4, true ).toString();
             if ( !s.equals( "((A,(B11,B12)),(C,D));" ) ) {
                 return false;
             }
@@ -2984,7 +3711,7 @@ public final class Test {
             if ( !n.getName().equals( "D" ) ) {
                 return false;
             }
-            s = w.toNewHampshire( t4, false, true ).toString();
+            s = w.toNewHampshire( t4, true ).toString();
             if ( !s.equals( "((A,B12),D);" ) ) {
                 return false;
             }
@@ -2993,7 +3720,7 @@ public final class Test {
             if ( t5.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t5, false, true ).toString();
+            s = w.toNewHampshire( t5, true ).toString();
             if ( !s.equals( "(((B11,B12),B2),(C,D));" ) ) {
                 return false;
             }
@@ -3002,7 +3729,7 @@ public final class Test {
             if ( t6.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t6, false, false ).toString();
+            s = w.toNewHampshire( t6, false ).toString();
             if ( !s.equals( "((A,(B12,B2)),(C,D));" ) ) {
                 return false;
             }
@@ -3011,7 +3738,7 @@ public final class Test {
             if ( t7.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t7, false, true ).toString();
+            s = w.toNewHampshire( t7, true ).toString();
             if ( !s.equals( "((A,(B11,B2)),(C,D));" ) ) {
                 return false;
             }
@@ -3020,7 +3747,7 @@ public final class Test {
             if ( t8.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t8, false, false ).toString();
+            s = w.toNewHampshire( t8, false ).toString();
             if ( !s.equals( "((A,(B11,B12)),(C,D));" ) ) {
                 return false;
             }
@@ -3029,7 +3756,7 @@ public final class Test {
             if ( t9.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t9, false, true ).toString();
+            s = w.toNewHampshire( t9, true ).toString();
             if ( !s.equals( "((A,((B11,B12),B2)),D);" ) ) {
                 return false;
             }
@@ -3038,7 +3765,7 @@ public final class Test {
             if ( t10.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t10, false, true ).toString();
+            s = w.toNewHampshire( t10, true ).toString();
             if ( !s.equals( "((A,((B11,B12),B2)),C);" ) ) {
                 return false;
             }
@@ -3047,7 +3774,7 @@ public final class Test {
             if ( t11.getNumberOfExternalNodes() != 2 ) {
                 return false;
             }
-            s = w.toNewHampshire( t11, false, true ).toString();
+            s = w.toNewHampshire( t11, true ).toString();
             if ( !s.equals( "(B,C);" ) ) {
                 return false;
             }
@@ -3055,7 +3782,7 @@ public final class Test {
             if ( t11.getNumberOfExternalNodes() != 1 ) {
                 return false;
             }
-            s = w.toNewHampshire( t11, false, false ).toString();
+            s = w.toNewHampshire( t11, false ).toString();
             if ( !s.equals( "B;" ) ) {
                 return false;
             }
@@ -3064,7 +3791,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 8 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "((A1,A2,A3),(B1,B3),(C1,C2,C3));" ) ) {
                 return false;
             }
@@ -3072,7 +3799,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 7 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "((A1,A2,A3),B1,(C1,C2,C3));" ) ) {
                 return false;
             }
@@ -3080,7 +3807,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 6 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "((A1,A2,A3),B1,(C1,C2));" ) ) {
                 return false;
             }
@@ -3088,7 +3815,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "((A2,A3),B1,(C1,C2));" ) ) {
                 return false;
             }
@@ -3096,7 +3823,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 4 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "((A2,A3),(C1,C2));" ) ) {
                 return false;
             }
@@ -3104,7 +3831,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 3 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "(A2,(C1,C2));" ) ) {
                 return false;
             }
@@ -3112,7 +3839,7 @@ public final class Test {
             if ( t12.getNumberOfExternalNodes() != 2 ) {
                 return false;
             }
-            s = w.toNewHampshire( t12, false, true ).toString();
+            s = w.toNewHampshire( t12, true ).toString();
             if ( !s.equals( "(C1,C2);" ) ) {
                 return false;
             }
@@ -3121,7 +3848,7 @@ public final class Test {
             if ( t13.getNumberOfExternalNodes() != 4 ) {
                 return false;
             }
-            s = w.toNewHampshire( t13, false, true ).toString();
+            s = w.toNewHampshire( t13, true ).toString();
             if ( !s.equals( "(A,B,C,E:5.0);" ) ) {
                 return false;
             }
@@ -3130,7 +3857,7 @@ public final class Test {
             if ( t14.getNumberOfExternalNodes() != 5 ) {
                 return false;
             }
-            s = w.toNewHampshire( t14, false, true ).toString();
+            s = w.toNewHampshire( t14, true ).toString();
             if ( !s.equals( "((A,B,C,D:1.1),F);" ) ) {
                 return false;
             }
@@ -3373,51 +4100,184 @@ public final class Test {
         return true;
     }
 
-    private static boolean testGenbankAccessorParsing() {
-        //The format for GenBank Accession numbers are:
-        //Nucleotide: 1 letter + 5 numerals OR 2 letters + 6 numerals
-        //Protein:    3 letters + 5 numerals
-        //http://www.ncbi.nlm.nih.gov/Sequin/acc.html
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "AY423861" ).equals( "AY423861" ) ) {
-            return false;
-        }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( ".AY423861.2" ).equals( "AY423861.2" ) ) {
-            return false;
-        }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "345_.AY423861.24_345" ).equals( "AY423861.24" ) ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AAY423861" ) != null ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AY4238612" ) != null ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AAY4238612" ) != null ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "Y423861" ) != null ) {
-            return false;
-        }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "S12345" ).equals( "S12345" ) ) {
-            return false;
-        }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "|S12345|" ).equals( "S12345" ) ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "|S123456" ) != null ) {
-            return false;
-        }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "ABC123456" ) != null ) {
-            return false;
-        }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "ABC12345" ).equals( "ABC12345" ) ) {
-            return false;
+    private static boolean testEbiEntryRetrieval() {
+        try {
+            final SequenceDatabaseEntry entry = SequenceDbWsTools.obtainEntry( "AAK41263" );
+            if ( !entry.getAccession().equals( "AAK41263" ) ) {
+                System.out.println( entry.getAccession() );
+                return false;
+            }
+            if ( !entry.getTaxonomyScientificName().equals( "Sulfolobus solfataricus P2" ) ) {
+                System.out.println( entry.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry.getSequenceName()
+                    .equals( "Sulfolobus solfataricus P2 Glycogen debranching enzyme, hypothetical (treX-like)" ) ) {
+                System.out.println( entry.getSequenceName() );
+                return false;
+            }
+            if ( !entry.getGeneName().equals( "treX-like" ) ) {
+                System.out.println( entry.getGeneName() );
+                return false;
+            }
+            if ( !entry.getTaxonomyIdentifier().equals( "273057" ) ) {
+                System.out.println( entry.getTaxonomyIdentifier() );
+                return false;
+            }
+            if ( !entry.getAnnotations().first().getRefValue().equals( "3.2.1.33" ) ) {
+                System.out.println( entry.getAnnotations().first().getRefValue() );
+                return false;
+            }
+            if ( !entry.getAnnotations().first().getRefSource().equals( "EC" ) ) {
+                System.out.println( entry.getAnnotations().first().getRefSource() );
+                return false;
+            }
+            if ( entry.getCrossReferences().size() < 1 ) {
+                return false;
+            }
+            final SequenceDatabaseEntry entry1 = SequenceDbWsTools.obtainEntry( "ABJ16409" );
+            if ( !entry1.getAccession().equals( "ABJ16409" ) ) {
+                return false;
+            }
+            if ( !entry1.getTaxonomyScientificName().equals( "Felis catus" ) ) {
+                System.out.println( entry1.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry1.getSequenceName().equals( "Felis catus (domestic cat) partial BCL2" ) ) {
+                System.out.println( entry1.getSequenceName() );
+                return false;
+            }
+            if ( !entry1.getTaxonomyIdentifier().equals( "9685" ) ) {
+                System.out.println( entry1.getTaxonomyIdentifier() );
+                return false;
+            }
+            if ( !entry1.getGeneName().equals( "BCL2" ) ) {
+                System.out.println( entry1.getGeneName() );
+                return false;
+            }
+            if ( entry1.getCrossReferences().size() < 1 ) {
+                return false;
+            }
+            final SequenceDatabaseEntry entry2 = SequenceDbWsTools.obtainEntry( "NM_184234" );
+            if ( !entry2.getAccession().equals( "NM_184234" ) ) {
+                return false;
+            }
+            if ( !entry2.getTaxonomyScientificName().equals( "Homo sapiens" ) ) {
+                System.out.println( entry2.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry2.getSequenceName()
+                    .equals( "Homo sapiens RNA binding motif protein 39 (RBM39), transcript variant 1, mRNA" ) ) {
+                System.out.println( entry2.getSequenceName() );
+                return false;
+            }
+            if ( !entry2.getTaxonomyIdentifier().equals( "9606" ) ) {
+                System.out.println( entry2.getTaxonomyIdentifier() );
+                return false;
+            }
+            if ( !entry2.getGeneName().equals( "RBM39" ) ) {
+                System.out.println( entry2.getGeneName() );
+                return false;
+            }
+            if ( entry2.getCrossReferences().size() < 1 ) {
+                return false;
+            }
+            if ( !entry2.getChromosome().equals( "20" ) ) {
+                return false;
+            }
+            if ( !entry2.getMap().equals( "20q11.22" ) ) {
+                return false;
+            }
+            final SequenceDatabaseEntry entry3 = SequenceDbWsTools.obtainEntry( "HM043801" );
+            if ( !entry3.getAccession().equals( "HM043801" ) ) {
+                return false;
+            }
+            if ( !entry3.getTaxonomyScientificName().equals( "Bursaphelenchus xylophilus" ) ) {
+                System.out.println( entry3.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry3.getSequenceName().equals( "Bursaphelenchus xylophilus RAF gene, complete cds" ) ) {
+                System.out.println( entry3.getSequenceName() );
+                return false;
+            }
+            if ( !entry3.getTaxonomyIdentifier().equals( "6326" ) ) {
+                System.out.println( entry3.getTaxonomyIdentifier() );
+                return false;
+            }
+            if ( !entry3.getSequenceSymbol().equals( "RAF" ) ) {
+                System.out.println( entry3.getSequenceSymbol() );
+                return false;
+            }
+            if ( !ForesterUtil.isEmpty( entry3.getGeneName() ) ) {
+                return false;
+            }
+            if ( entry3.getCrossReferences().size() < 1 ) {
+                return false;
+            }
+            final SequenceDatabaseEntry entry4 = SequenceDbWsTools.obtainEntry( "AAA36557.1" );
+            if ( !entry4.getAccession().equals( "AAA36557" ) ) {
+                return false;
+            }
+            if ( !entry4.getTaxonomyScientificName().equals( "Homo sapiens" ) ) {
+                System.out.println( entry4.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry4.getSequenceName().equals( "Homo sapiens (human) ras protein" ) ) {
+                System.out.println( entry4.getSequenceName() );
+                return false;
+            }
+            if ( !entry4.getTaxonomyIdentifier().equals( "9606" ) ) {
+                System.out.println( entry4.getTaxonomyIdentifier() );
+                return false;
+            }
+            if ( !entry4.getGeneName().equals( "ras" ) ) {
+                System.out.println( entry4.getGeneName() );
+                return false;
+            }
+            final SequenceDatabaseEntry entry5 = SequenceDbWsTools.obtainEntry( "AAZ45343.1" );
+            if ( !entry5.getAccession().equals( "AAZ45343" ) ) {
+                return false;
+            }
+            if ( !entry5.getTaxonomyScientificName().equals( "Dechloromonas aromatica RCB" ) ) {
+                System.out.println( entry5.getTaxonomyScientificName() );
+                return false;
+            }
+            if ( !entry5.getSequenceName().equals( "Dechloromonas aromatica RCB 1,4-alpha-glucan branching enzyme" ) ) {
+                System.out.println( entry5.getSequenceName() );
+                return false;
+            }
+            if ( !entry5.getTaxonomyIdentifier().equals( "159087" ) ) {
+                System.out.println( entry5.getTaxonomyIdentifier() );
+                return false;
+            }
+            final SequenceDatabaseEntry entry6 = SequenceDbWsTools.obtainEntry( "M30539" );
+            if ( !entry6.getAccession().equals( "M30539" ) ) {
+                return false;
+            }
+            if ( !entry6.getGeneName().equals( "ras" ) ) {
+                return false;
+            }
+            if ( !entry6.getSequenceName().equals( "Human SK2 c-Ha-ras-1 oncogene-encoded protein gene, exon 1" ) ) {
+                return false;
+            }
+            if ( !entry6.getTaxonomyIdentifier().equals( "9606" ) ) {
+                return false;
+            }
+            if ( !entry6.getTaxonomyScientificName().equals( "Homo sapiens" ) ) {
+                return false;
+            }
+            if ( entry6.getCrossReferences().size() < 1 ) {
+                return false;
+            }
         }
-        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "&ABC12345&" ).equals( "ABC12345" ) ) {
-            return false;
+        catch ( final IOException e ) {
+            System.out.println();
+            System.out.println( "the following might be due to absence internet connection:" );
+            e.printStackTrace( System.out );
+            return true;
         }
-        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "ABCD12345" ) != null ) {
+        catch ( final Exception e ) {
+            e.printStackTrace();
             return false;
         }
         return true;
@@ -3540,21 +4400,273 @@ public final class Test {
             if ( !ParserUtils.extractScientificNameFromNodeName( "BCDO2_Mus_musculus" ).equals( "Mus musculus" ) ) {
                 return false;
             }
-            if ( !ParserUtils.extractScientificNameFromNodeName( "BCDO2_Mus_musculus_musculus" )
+            if ( !ParserUtils.extractScientificNameFromNodeName( "BCDO2 Mus musculus" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_BCDO2" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus musculus musculus BCDO2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_musculus_BCDO2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "BCDO2 Mus musculus musculus" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Bcl Mus musculus musculus" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( ParserUtils.extractScientificNameFromNodeName( "vcl Mus musculus musculus" ) != null ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "could_be_anything_Mus_musculus_musculus_BCDO2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "could_be_anything_Mus_musculus_musculus_Musculus" )
                     .equals( "Mus musculus musculus" ) ) {
                 return false;
             }
-            if ( !ParserUtils.extractScientificNameFromNodeName( "BCDO2_Mus_musculus_musculus-12" )
+            if ( ParserUtils.extractScientificNameFromNodeName( "could_be_anything_Mus_musculus_musculus_musculus" ) != null ) {
+                return false;
+            }
+            if ( ParserUtils.extractScientificNameFromNodeName( "musculus" ) != null ) {
+                return false;
+            }
+            if ( ParserUtils.extractScientificNameFromNodeName( "mus_musculus" ) != null ) {
+                return false;
+            }
+            if ( ParserUtils.extractScientificNameFromNodeName( "mus_musculus_musculus" ) != null ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_musculus_1" )
                     .equals( "Mus musculus musculus" ) ) {
                 return false;
             }
-            if ( !ParserUtils.extractScientificNameFromNodeName( " -XS12_Mus_musculus-12" ).equals( "Mus musculus" ) ) {
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_1" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_bcl" ) != null ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_BCL" ).equals( "Mus musculus" ) ) {
                 return false;
             }
-            if ( !ParserUtils.extractScientificNameFromNodeName( " -1234_Mus_musculus-12 affrre e" )
+            if ( ParserUtils.extractScientificNameFromNodeName( "Mus musculus bcl" ) != null ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus musculus BCL" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus musculus xBCL" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus musculus x1" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( " -XS12_Mus_musculus_12" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( " -1234_Mus_musculus_12 affrre e" )
+                    .equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( " -1234_Mus_musculus_12_affrre_e" )
                     .equals( "Mus musculus" ) ) {
                 return false;
             }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_musculus_2bcl2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_musculus_2bcl2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_musculus_bcl2" )
+                    .equals( "Mus musculus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Mus_musculus_123" ).equals( "Mus musculus" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Pilostyles mexicana Mexico Breedlove 27233" )
+                    .equals( "Pilostyles mexicana" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia_coli_strain_K12/DH10B" )
+                    .equals( "Escherichia coli strain K12/DH10B" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia_coli_str_K12/DH10B" )
+                    .equals( "Escherichia coli str. K12/DH10B" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli str. K12/DH10B" )
+                    .equals( "Escherichia coli str. K12/DH10B" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis_lyrata_subsp_lyrata" )
+                    .equals( "Arabidopsis lyrata subsp. lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis lyrata subsp. lyrata" )
+                    .equals( "Arabidopsis lyrata subsp. lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis lyrata subsp. lyrata 395" )
+                    .equals( "Arabidopsis lyrata subsp. lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis lyrata subsp. lyrata bcl2" )
+                    .equals( "Arabidopsis lyrata subsp. lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis lyrata subsp lyrata bcl2" )
+                    .equals( "Arabidopsis lyrata subsp. lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Arabidopsis lyrata subspecies lyrata bcl2" )
+                    .equals( "Arabidopsis lyrata subspecies lyrata" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Verbascum sinuatum var. adenosepalum bcl2" )
+                    .equals( "Verbascum sinuatum var. adenosepalum" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (strain K12)" )
+                    .equals( "Escherichia coli (strain K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (strain K12) bcl2" )
+                    .equals( "Escherichia coli (strain K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (str. K12)" )
+                    .equals( "Escherichia coli (str. K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (str K12)" )
+                    .equals( "Escherichia coli (str. K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (str. K12) bcl2" )
+                    .equals( "Escherichia coli (str. K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli (var K12) bcl2" )
+                    .equals( "Escherichia coli (var. K12)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli str. K-12 substr. MG1655star" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli str K-12 substr MG1655star" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils
+                    .extractScientificNameFromNodeName( "could be anything Escherichia coli str K-12 substr MG1655star" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia coli str K-12 substr MG1655star gene1" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils
+                    .extractScientificNameFromNodeName( "could be anything Escherichia coli str K-12 substr MG1655star GENE1" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia_coli_str_K-12_substr_MG1655star" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Escherichia_coli_str_K-12_substr_MG1655star" )
+                    .equals( "Escherichia coli str. K-12 substr. MG1655star" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Macrocera sp." ).equals( "Macrocera sp." ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Macrocera sp. 123" ).equals( "Macrocera sp." ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Macrocera sp. K12" ).equals( "Macrocera sp." ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "something Macrocera sp. K12" )
+                    .equals( "Macrocera sp." ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Macrocera sp" ).equals( "Macrocera sp." ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Sesamum rigidum ssp merenskyanum 07 48" )
+                    .equals( "Sesamum rigidum subsp. merenskyanum" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Sesamum rigidum ssp. merenskyanum" )
+                    .equals( "Sesamum rigidum subsp. merenskyanum" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Sesamum rigidum (ssp. merenskyanum)" )
+                    .equals( "Sesamum rigidum (subsp. merenskyanum)" ) ) {
+                return false;
+            }
+            if ( !ParserUtils.extractScientificNameFromNodeName( "Sesamum rigidum (ssp merenskyanum)" )
+                    .equals( "Sesamum rigidum (subsp. merenskyanum)" ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testExtractTaxonomyDataFromNodeName() {
+        try {
+            PhylogenyNode n = new PhylogenyNode( "tr|B1AM49|B1AM49_HUMAN" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "tr|B1AM49|B1AM49_HUMAN~1-2" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "tr|B1AM49|HNRPR_HUMAN" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "tr|B1AM49|HNRPR_HUMAN|" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "tr|B1AM49|HNRPR_HUMAN~12" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "HNRPR_HUMAN" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
+            n = new PhylogenyNode( "HNRPR_HUMAN_X" );
+            if ( !ParserUtils.extractTaxonomyDataFromNodeName( n, TAXONOMY_EXTRACTION.AGGRESSIVE ).equals( "HUMAN" ) ) {
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -3638,17 +4750,17 @@ public final class Test {
             }
             if ( !ParserUtils.extractTaxonomyCodeFromNodeName( "BCL2_MOUSE function = 23445",
                                                                TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED )
-                    .equals( "MOUSE" ) ) {
+                                                               .equals( "MOUSE" ) ) {
                 return false;
             }
             if ( !ParserUtils.extractTaxonomyCodeFromNodeName( "BCL2_MOUSE+function = 23445",
                                                                TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED )
-                    .equals( "MOUSE" ) ) {
+                                                               .equals( "MOUSE" ) ) {
                 return false;
             }
             if ( !ParserUtils.extractTaxonomyCodeFromNodeName( "BCL2_MOUSE|function = 23445",
                                                                TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED )
-                    .equals( "MOUSE" ) ) {
+                                                               .equals( "MOUSE" ) ) {
                 return false;
             }
             if ( ParserUtils.extractTaxonomyCodeFromNodeName( "BCL2_MOUSEfunction = 23445",
@@ -3883,12 +4995,22 @@ public final class Test {
 
     private static boolean testFastaParser() {
         try {
-            if ( !FastaParser.isLikelyFasta( new FileInputStream( PATH_TO_TEST_DATA + "fasta_0.fasta" ) ) ) {
+            FileInputStream fis1 = new FileInputStream( PATH_TO_TEST_DATA + "fasta_0.fasta" );
+            if ( !FastaParser.isLikelyFasta( fis1 ) ) {
+                fis1.close();
                 return false;
             }
-            if ( FastaParser.isLikelyFasta( new FileInputStream( PATH_TO_TEST_DATA + "msa_3.txt" ) ) ) {
+            else {
+                fis1.close();
+            }
+            FileInputStream fis2 = new FileInputStream( PATH_TO_TEST_DATA + "msa_3.txt" );
+            if ( FastaParser.isLikelyFasta( fis2 ) ) {
+                fis2.close();
                 return false;
             }
+            else {
+                fis2.close();
+            }
             final Msa msa_0 = FastaParser.parseMsa( new FileInputStream( PATH_TO_TEST_DATA + "fasta_0.fasta" ) );
             if ( !msa_0.getSequenceAsString( 0 ).toString().equalsIgnoreCase( "ACGTGKXFMFDMXEXXXSFMFMF" ) ) {
                 return false;
@@ -3899,7 +5021,7 @@ public final class Test {
             if ( !msa_0.getSequenceAsString( 1 ).toString().equalsIgnoreCase( "DKXASDFXSFXFKFKSXDFKSLX" ) ) {
                 return false;
             }
-            if ( !msa_0.getSequenceAsString( 2 ).toString().equalsIgnoreCase( "SXDFKSXLFSFPWEXPRXWXERR" ) ) {
+            if ( !msa_0.getSequenceAsString( 2 ).toString().equalsIgnoreCase( "SXDFKSXLFSFPWEXPROWXERR" ) ) {
                 return false;
             }
             if ( !msa_0.getSequenceAsString( 3 ).toString().equalsIgnoreCase( "AAAAAAAAAAAAAAAAAAAAAAA" ) ) {
@@ -3916,6 +5038,56 @@ public final class Test {
         return true;
     }
 
+    private static boolean testGenbankAccessorParsing() {
+        //The format for GenBank Accession numbers are:
+        //Nucleotide: 1 letter + 5 numerals OR 2 letters + 6 numerals
+        //Protein:    3 letters + 5 numerals
+        //http://www.ncbi.nlm.nih.gov/Sequin/acc.html
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "AY423861" ).equals( "AY423861" ) ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( ".AY423861.2" ).equals( "AY423861.2" ) ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "345_.AY423861.24_345" ).equals( "AY423861.24" ) ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AAY423861" ) != null ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AY4238612" ) != null ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "AAY4238612" ) != null ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "Y423861" ) != null ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "S12345" ).equals( "S12345" ) ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "|S12345|" ).equals( "S12345" ) ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "|S123456" ) != null ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "ABC123456" ) != null ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "ABC12345" ).equals( "ABC12345" ) ) {
+            return false;
+        }
+        if ( !SequenceAccessionTools.parseGenbankAccessorFromString( "&ABC12345&" ).equals( "ABC12345" ) ) {
+            return false;
+        }
+        if ( SequenceAccessionTools.parseGenbankAccessorFromString( "ABCD12345" ) != null ) {
+            return false;
+        }
+        return true;
+    }
+
     private static boolean testGeneralMsaParser() {
         try {
             final String msa_str_0 = "seq1 abcd\n\nseq2 efgh\n";
@@ -4439,14 +5611,15 @@ public final class Test {
     private static boolean testGetLCA2() {
         try {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            final Phylogeny p_a = factory.create( "(a)", new NHXParser() )[ 0 ];
+            // final Phylogeny p_a = factory.create( "(a)", new NHXParser() )[ 0 ];
+            final Phylogeny p_a = NHXParser.parse( "(a)" )[ 0 ];
             PhylogenyMethods.preOrderReId( p_a );
             final PhylogenyNode p_a_1 = PhylogenyMethods.calculateLCAonTreeWithIdsInPreOrder( p_a.getNode( "a" ),
                                                                                               p_a.getNode( "a" ) );
             if ( !p_a_1.getName().equals( "a" ) ) {
                 return false;
             }
-            final Phylogeny p_b = factory.create( "((a)b)", new NHXParser() )[ 0 ];
+            final Phylogeny p_b = NHXParser.parse( "((a)b)" )[ 0 ];
             PhylogenyMethods.preOrderReId( p_b );
             final PhylogenyNode p_b_1 = PhylogenyMethods.calculateLCAonTreeWithIdsInPreOrder( p_b.getNode( "b" ),
                                                                                               p_b.getNode( "a" ) );
@@ -4768,10 +5941,10 @@ public final class Test {
         final String test_dir = Test.PATH_TO_TEST_DATA;
         try {
             final HmmscanPerDomainTableParser parser1 = new HmmscanPerDomainTableParser( new File( test_dir
-                    + ForesterUtil.getFileSeparator() + "hmmscan30b3_output_1" ), "MONBR", INDIVIDUAL_SCORE_CUTOFF.NONE );
+                                                                                                   + ForesterUtil.getFileSeparator() + "hmmscan30b3_output_1" ), "MONBR", INDIVIDUAL_SCORE_CUTOFF.NONE );
             parser1.parse();
             final HmmscanPerDomainTableParser parser2 = new HmmscanPerDomainTableParser( new File( test_dir
-                    + ForesterUtil.getFileSeparator() + "hmmscan30b3_output_2" ), "MONBR", INDIVIDUAL_SCORE_CUTOFF.NONE );
+                                                                                                   + ForesterUtil.getFileSeparator() + "hmmscan30b3_output_2" ), "MONBR", INDIVIDUAL_SCORE_CUTOFF.NONE );
             final List<Protein> proteins = parser2.parse();
             if ( parser2.getProteinsEncountered() != 4 ) {
                 return false;
@@ -4785,7 +5958,10 @@ public final class Test {
             if ( parser2.getDomainsIgnoredDueToDuf() != 0 ) {
                 return false;
             }
-            if ( parser2.getDomainsIgnoredDueToEval() != 0 ) {
+            if ( parser2.getDomainsIgnoredDueToFsEval() != 0 ) {
+                return false;
+            }
+            if ( parser2.getDomainsIgnoredDueToIEval() != 0 ) {
                 return false;
             }
             final Protein p1 = proteins.get( 0 );
@@ -4825,12 +6001,6 @@ public final class Test {
             if ( !Test.isEqual( p4.getProteinDomain( 0 ).getPerDomainScore(), 135.7 ) ) {
                 return false;
             }
-            if ( !Test.isEqual( p4.getProteinDomain( 0 ).getPerSequenceEvalue(), 8.3e-40 ) ) {
-                return false;
-            }
-            if ( !Test.isEqual( p4.getProteinDomain( 0 ).getPerSequenceScore(), 136.3 ) ) {
-                return false;
-            }
             if ( !Test.isEqual( p4.getProteinDomain( 0 ).getNumber(), 1 ) ) {
                 return false;
             }
@@ -5139,11 +6309,11 @@ public final class Test {
 
     private static boolean testMsaQualityMethod() {
         try {
-            final Sequence s0 = BasicSequence.createAaSequence( "a", "ABAXEFGHIJ" );
-            final Sequence s1 = BasicSequence.createAaSequence( "b", "ABBXEFGHIJ" );
-            final Sequence s2 = BasicSequence.createAaSequence( "c", "AXCXEFGHIJ" );
-            final Sequence s3 = BasicSequence.createAaSequence( "d", "AXDDEFGHIJ" );
-            final List<Sequence> l = new ArrayList<Sequence>();
+            final MolecularSequence s0 = BasicSequence.createAaSequence( "a", "ABAXEFGHIJJE-" );
+            final MolecularSequence s1 = BasicSequence.createAaSequence( "b", "ABBXEFGHIJJBB" );
+            final MolecularSequence s2 = BasicSequence.createAaSequence( "c", "AXCXEFGHIJJ--" );
+            final MolecularSequence s3 = BasicSequence.createAaSequence( "d", "AXDDEFGHIJ---" );
+            final List<MolecularSequence> l = new ArrayList<MolecularSequence>();
             l.add( s0 );
             l.add( s1 );
             l.add( s2 );
@@ -5161,6 +6331,238 @@ public final class Test {
             if ( !isEqual( 0.75, MsaMethods.calculateIdentityRatio( msa, 3 ) ) ) {
                 return false;
             }
+            if ( !isEqual( 0.75, MsaMethods.calculateIdentityRatio( msa, 10 ) ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.25, MsaMethods.calculateIdentityRatio( msa, 11 ) ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.25, MsaMethods.calculateIdentityRatio( msa, 12 ) ) ) {
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testMsaEntropy() {
+        try {
+            final MolecularSequence s0 = BasicSequence.createAaSequence( "a", "AAAAAAA" );
+            final MolecularSequence s1 = BasicSequence.createAaSequence( "b", "AAAIACC" );
+            final MolecularSequence s2 = BasicSequence.createAaSequence( "c", "AAIIIIF" );
+            final MolecularSequence s3 = BasicSequence.createAaSequence( "d", "AIIIVVW" );
+            final List<MolecularSequence> l = new ArrayList<MolecularSequence>();
+            l.add( s0 );
+            l.add( s1 );
+            l.add( s2 );
+            l.add( s3 );
+            final Msa msa = BasicMsa.createInstance( l );
+            //TODO need to DO the tests!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
+            //FIXME
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 0 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 1 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 2 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 3 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 4 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 5 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa, 6 ) );
+            //            System.out.println();
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 0 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 1 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 2 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 3 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 4 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 5 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 6, msa, 6 ) );
+            final List<MolecularSequence> l2 = new ArrayList<MolecularSequence>();
+            l2.add( BasicSequence.createAaSequence( "1", "AAAAAAA" ) );
+            l2.add( BasicSequence.createAaSequence( "2", "AAAIACC" ) );
+            l2.add( BasicSequence.createAaSequence( "3", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "4", "AIIIVVW" ) );
+            l2.add( BasicSequence.createAaSequence( "5", "AAAAAAA" ) );
+            l2.add( BasicSequence.createAaSequence( "6", "AAAIACC" ) );
+            l2.add( BasicSequence.createAaSequence( "7", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "8", "AIIIVVW" ) );
+            l2.add( BasicSequence.createAaSequence( "9", "AAAAAAA" ) );
+            l2.add( BasicSequence.createAaSequence( "10", "AAAIACC" ) );
+            l2.add( BasicSequence.createAaSequence( "11", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "12", "AIIIVVW" ) );
+            l2.add( BasicSequence.createAaSequence( "13", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "14", "AIIIVVW" ) );
+            l2.add( BasicSequence.createAaSequence( "15", "AAAAAAA" ) );
+            l2.add( BasicSequence.createAaSequence( "16", "AAAIACC" ) );
+            l2.add( BasicSequence.createAaSequence( "17", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "18", "AIIIVVW" ) );
+            l2.add( BasicSequence.createAaSequence( "19", "AAAAAAA" ) );
+            l2.add( BasicSequence.createAaSequence( "20", "AAAIACC" ) );
+            l2.add( BasicSequence.createAaSequence( "21", "AAIIIIF" ) );
+            l2.add( BasicSequence.createAaSequence( "22", "AIIIVVW" ) );
+            final Msa msa2 = BasicMsa.createInstance( l2 );
+            //            System.out.println();
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa2, 0 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa2, 1 ) );
+            //            System.out.println( MsaMethods.calcNormalizedShannonsEntropy( 20, msa2, 2 ) );
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testDeleteableMsa() {
+        try {
+            final MolecularSequence s0 = BasicSequence.createAaSequence( "a", "AAAA" );
+            final MolecularSequence s1 = BasicSequence.createAaSequence( "b", "BAAA" );
+            final MolecularSequence s2 = BasicSequence.createAaSequence( "c", "CAAA" );
+            final MolecularSequence s3 = BasicSequence.createAaSequence( "d", "DAAA" );
+            final MolecularSequence s4 = BasicSequence.createAaSequence( "e", "EAAA" );
+            final MolecularSequence s5 = BasicSequence.createAaSequence( "f", "FAAA" );
+            final List<MolecularSequence> l0 = new ArrayList<MolecularSequence>();
+            l0.add( s0 );
+            l0.add( s1 );
+            l0.add( s2 );
+            l0.add( s3 );
+            l0.add( s4 );
+            l0.add( s5 );
+            final DeleteableMsa dmsa0 = DeleteableMsa.createInstance( l0 );
+            dmsa0.deleteRow( "b", false );
+            if ( !dmsa0.getIdentifier( 1 ).equals( "c" ) ) {
+                return false;
+            }
+            dmsa0.deleteRow( "e", false );
+            dmsa0.deleteRow( "a", false );
+            dmsa0.deleteRow( "f", false );
+            if ( dmsa0.getLength() != 4 ) {
+                return false;
+            }
+            if ( dmsa0.getNumberOfSequences() != 2 ) {
+                return false;
+            }
+            if ( !dmsa0.getIdentifier( 0 ).equals( "c" ) ) {
+                return false;
+            }
+            if ( !dmsa0.getIdentifier( 1 ).equals( "d" ) ) {
+                return false;
+            }
+            if ( dmsa0.getResidueAt( 0, 0 ) != 'C' ) {
+                return false;
+            }
+            if ( !dmsa0.getSequenceAsString( 0 ).toString().equals( "CAAA" ) ) {
+                return false;
+            }
+            if ( dmsa0.getColumnAt( 0 ).size() != 2 ) {
+                return false;
+            }
+            dmsa0.deleteRow( "c", false );
+            dmsa0.deleteRow( "d", false );
+            if ( dmsa0.getNumberOfSequences() != 0 ) {
+                return false;
+            }
+            //
+            final MolecularSequence s_0 = BasicSequence.createAaSequence( "a", "--A---B-C--X----" );
+            final MolecularSequence s_1 = BasicSequence.createAaSequence( "b", "--B-----C-------" );
+            final MolecularSequence s_2 = BasicSequence.createAaSequence( "c", "--C--AB-C------Z" );
+            final MolecularSequence s_3 = BasicSequence.createAaSequence( "d", "--D--AA-C-------" );
+            final MolecularSequence s_4 = BasicSequence.createAaSequence( "e", "--E--AA-C-------" );
+            final MolecularSequence s_5 = BasicSequence.createAaSequence( "f", "--F--AB-CD--Y---" );
+            final List<MolecularSequence> l1 = new ArrayList<MolecularSequence>();
+            l1.add( s_0 );
+            l1.add( s_1 );
+            l1.add( s_2 );
+            l1.add( s_3 );
+            l1.add( s_4 );
+            l1.add( s_5 );
+            final DeleteableMsa dmsa1 = DeleteableMsa.createInstance( l1 );
+            dmsa1.deleteGapOnlyColumns();
+            dmsa1.deleteRow( "a", false );
+            dmsa1.deleteRow( "f", false );
+            dmsa1.deleteRow( "d", false );
+            dmsa1.deleteGapOnlyColumns();
+            if ( !dmsa1.getSequenceAsString( 0 ).toString().equals( "B--C-" ) ) {
+                return false;
+            }
+            if ( !dmsa1.getSequenceAsString( 1 ).toString().equals( "CABCZ" ) ) {
+                return false;
+            }
+            if ( !dmsa1.getSequenceAsString( 2 ).toString().equals( "EAAC-" ) ) {
+                return false;
+            }
+            dmsa1.deleteRow( "c", false );
+            dmsa1.deleteGapOnlyColumns();
+            final Writer w0 = new StringWriter();
+            dmsa1.write( w0, MSA_FORMAT.FASTA );
+            final Writer w1 = new StringWriter();
+            dmsa1.write( w1, MSA_FORMAT.PHYLIP );
+            if ( !dmsa1.getSequenceAsString( 0 ).toString().equals( "B--C" ) ) {
+                return false;
+            }
+            if ( !dmsa1.getSequenceAsString( 1 ).toString().equals( "EAAC" ) ) {
+                return false;
+            }
+            final MolecularSequence s__0 = BasicSequence.createAaSequence( "a", "A------" );
+            final MolecularSequence s__1 = BasicSequence.createAaSequence( "b", "BB-----" );
+            final MolecularSequence s__2 = BasicSequence.createAaSequence( "c", "CCC----" );
+            final MolecularSequence s__3 = BasicSequence.createAaSequence( "d", "DDDD---" );
+            final MolecularSequence s__4 = BasicSequence.createAaSequence( "e", "EEEEE--" );
+            final MolecularSequence s__5 = BasicSequence.createAaSequence( "f", "FFFFFF-" );
+            final List<MolecularSequence> l2 = new ArrayList<MolecularSequence>();
+            l2.add( s__0 );
+            l2.add( s__1 );
+            l2.add( s__2 );
+            l2.add( s__3 );
+            l2.add( s__4 );
+            l2.add( s__5 );
+            final DeleteableMsa dmsa2 = DeleteableMsa.createInstance( l2 );
+            dmsa2.deleteGapColumns( 0.5 );
+            if ( !dmsa2.getSequenceAsString( 0 ).toString().equals( "A---" ) ) {
+                return false;
+            }
+            if ( !dmsa2.getSequenceAsString( 1 ).toString().equals( "BB--" ) ) {
+                return false;
+            }
+            if ( !dmsa2.getSequenceAsString( 2 ).toString().equals( "CCC-" ) ) {
+                return false;
+            }
+            dmsa2.deleteGapColumns( 0.2 );
+            if ( !dmsa2.getSequenceAsString( 0 ).toString().equals( "A-" ) ) {
+                return false;
+            }
+            if ( !dmsa2.getSequenceAsString( 1 ).toString().equals( "BB" ) ) {
+                return false;
+            }
+            if ( !dmsa2.getSequenceAsString( 2 ).toString().equals( "CC" ) ) {
+                return false;
+            }
+            dmsa2.deleteGapColumns( 0 );
+            dmsa2.deleteRow( "a", false );
+            dmsa2.deleteRow( "b", false );
+            dmsa2.deleteRow( "f", false );
+            dmsa2.deleteRow( "e", false );
+            dmsa2.setIdentifier( 0, "new_c" );
+            dmsa2.setIdentifier( 1, "new_d" );
+            dmsa2.setResidueAt( 0, 0, 'x' );
+            final MolecularSequence s = dmsa2.deleteRow( "new_d", true );
+            if ( !s.getMolecularSequenceAsString().equals( "D" ) ) {
+                return false;
+            }
+            final Writer w = new StringWriter();
+            dmsa2.write( w, MSA_FORMAT.PHYLIP );
+            final String phylip = w.toString();
+            if ( !phylip.equals( "1 1" + ForesterUtil.LINE_SEPARATOR + "new_c x" + ForesterUtil.LINE_SEPARATOR ) ) {
+                System.out.println( phylip );
+                return false;
+            }
+            final Writer w2 = new StringWriter();
+            dmsa2.write( w2, MSA_FORMAT.FASTA );
+            final String fasta = w2.toString();
+            if ( !fasta.equals( ">new_c" + ForesterUtil.LINE_SEPARATOR + "x" + ForesterUtil.LINE_SEPARATOR ) ) {
+                System.out.println( fasta );
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -5228,8 +6630,6 @@ public final class Test {
             if ( !ext.get( 4 ).getName().equals( "h" ) ) {
                 return false;
             }
-            //
-            //
             ext.clear();
             final StringBuffer sb2 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t2 = factory.create( sb2, new NHXParser() )[ 0 ];
@@ -5258,8 +6658,6 @@ public final class Test {
             if ( !ext.get( 3 ).getName().equals( "gh" ) ) {
                 return false;
             }
-            //
-            //
             ext.clear();
             final StringBuffer sb3 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t3 = factory.create( sb3, new NHXParser() )[ 0 ];
@@ -5286,8 +6684,6 @@ public final class Test {
             if ( !ext.get( 2 ).getName().equals( "fgh" ) ) {
                 return false;
             }
-            //
-            //
             ext.clear();
             final StringBuffer sb4 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t4 = factory.create( sb4, new NHXParser() )[ 0 ];
@@ -5304,8 +6700,6 @@ public final class Test {
             if ( n.getNextExternalNodeWhileTakingIntoAccountCollapsedNodes() != null ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb5 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h))fgh)cdefgh)abcdefgh" );
             final Phylogeny t5 = factory.create( sb5, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5341,8 +6735,6 @@ public final class Test {
             if ( !ext.get( 7 ).getName().equals( "h" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb6 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h))fgh)cdefgh)abcdefgh" );
             final Phylogeny t6 = factory.create( sb6, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5376,8 +6768,6 @@ public final class Test {
             if ( !ext.get( 6 ).getName().equals( "h" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb7 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h))fgh)cdefgh)abcdefgh" );
             final Phylogeny t7 = factory.create( sb7, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5411,8 +6801,6 @@ public final class Test {
             if ( !ext.get( 6 ).getName().equals( "h" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb8 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h))fgh)cdefgh)abcdefgh" );
             final Phylogeny t8 = factory.create( sb8, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5449,8 +6837,6 @@ public final class Test {
             if ( !ext.get( 6 ).getName().equals( "h" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb9 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t9 = factory.create( sb9, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5484,8 +6870,6 @@ public final class Test {
             if ( !ext.get( 6 ).getName().equals( "gh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb10 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t10 = factory.create( sb10, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5521,8 +6905,6 @@ public final class Test {
             if ( !ext.get( 6 ).getName().equals( "gh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb11 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t11 = factory.create( sb11, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5554,8 +6936,6 @@ public final class Test {
             if ( !ext.get( 5 ).getName().equals( "fgh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb12 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t12 = factory.create( sb12, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5590,8 +6970,6 @@ public final class Test {
             if ( !ext.get( 5 ).getName().equals( "fgh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb13 = new StringBuffer( "((a,b)ab,(((c,d)cd,e)cde,(f,(g,h)gh)fgh)cdefgh)abcdefgh" );
             final Phylogeny t13 = factory.create( sb13, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5622,8 +7000,6 @@ public final class Test {
             if ( !ext.get( 4 ).getName().equals( "fgh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb14 = new StringBuffer( "((a,b,0)ab,(((c,d)cd,e)cde,(f,(g,h,1,2)gh,0)fgh)cdefgh)abcdefgh" );
             final Phylogeny t14 = factory.create( sb14, new NHXParser() )[ 0 ];
             ext.clear();
@@ -5654,8 +7030,6 @@ public final class Test {
             if ( !ext.get( 4 ).getName().equals( "fgh" ) ) {
                 return false;
             }
-            //
-            //
             final StringBuffer sb15 = new StringBuffer( "((a,b,0)ab,(((c,d)cd,e)cde,x,(f,(g,h,1,2)gh,0)fgh)cdefgh)abcdefgh" );
             final Phylogeny t15 = factory.create( sb15, new NHXParser() )[ 0 ];
             ext.clear();
@@ -6051,6 +7425,35 @@ public final class Test {
             if ( phylogenies[ 17 ].getNumberOfExternalNodes() != 10 ) {
                 return false;
             }
+            final NexusPhylogeniesParser p2 = new NexusPhylogeniesParser();
+            phylogenies = null;
+            phylogenies = factory.create( Test.PATH_TO_TEST_DATA + "S15613.nex", p2 );
+            if ( phylogenies.length != 9 ) {
+                return false;
+            }
+            if ( !isEqual( 0.48039661496919533, phylogenies[ 0 ].getNode( "Diadocidia_spinosula" )
+                           .getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.3959796191512233, phylogenies[ 0 ].getNode( "Diadocidia_stanfordensis" )
+                           .getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( !phylogenies[ 0 ].getName().equals( "Family Diadocidiidae MLT (Imported_tree_0)" ) ) {
+                return false;
+            }
+            if ( !phylogenies[ 1 ].getName().equals( "Family Diadocidiidae BAT (con_50_majrule)" ) ) {
+                return false;
+            }
+            if ( !phylogenies[ 2 ].getName().equals( "Family Diadocidiidae BAT (con_50_majrule)" ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.065284, phylogenies[ 7 ].getNode( "Bradysia_amoena" ).getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.065284, phylogenies[ 8 ].getNode( "Bradysia_amoena" ).getDistanceToParent() ) ) {
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -6083,7 +7486,6 @@ public final class Test {
             if ( phy != null ) {
                 return false;
             }
-            //
             p.reset();
             if ( !p.hasNext() ) {
                 return false;
@@ -6105,7 +7507,6 @@ public final class Test {
             if ( phy != null ) {
                 return false;
             }
-            ////
             p.setSource( Test.PATH_TO_TEST_DATA + "nexus_test_2.nex" );
             if ( !p.hasNext() ) {
                 return false;
@@ -6127,7 +7528,6 @@ public final class Test {
             if ( phy != null ) {
                 return false;
             }
-            //
             p.reset();
             if ( !p.hasNext() ) {
                 return false;
@@ -6149,7 +7549,6 @@ public final class Test {
             if ( phy != null ) {
                 return false;
             }
-            ////
             p.setSource( Test.PATH_TO_TEST_DATA + "nexus_test_3.nex" );
             if ( !p.hasNext() ) {
                 return false;
@@ -6196,15 +7595,12 @@ public final class Test {
             if ( phy != null ) {
                 return false;
             }
-            ////
+            //
             p.setSource( Test.PATH_TO_TEST_DATA + "nexus_test_4_1.nex" );
-            //            if ( phylogenies.length != 18 ) {
-            //                return false;
-            //            }
-            //0
             if ( !p.hasNext() ) {
                 return false;
             }
+            //0
             phy = p.next();
             if ( phy == null ) {
                 return false;
@@ -6238,6 +7634,7 @@ public final class Test {
                 return false;
             }
             if ( phy.getNumberOfExternalNodes() != 3 ) {
+                System.out.println( phy.toString() );
                 return false;
             }
             if ( !phy.getName().equals( "" ) ) {
@@ -6615,6 +8012,82 @@ public final class Test {
             if ( phy.isRooted() ) {
                 return false;
             }
+            //
+            final NexusPhylogeniesParser p2 = new NexusPhylogeniesParser();
+            p2.setSource( Test.PATH_TO_TEST_DATA + "S15613.nex" );
+            // 0
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            if ( !isEqual( 0.48039661496919533, phy.getNode( "Diadocidia_spinosula" ).getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.3959796191512233, phy.getNode( "Diadocidia_stanfordensis" ).getDistanceToParent() ) ) {
+                return false;
+            }
+            // 1
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 2
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 3
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 4
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 5
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 6
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 7
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            // 8
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            if ( !isEqual( 0.065284, phy.getNode( "Bradysia_amoena" ).getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            if ( phy != null ) {
+                return false;
+            }
+            // 0
+            p2.reset();
+            if ( !p2.hasNext() ) {
+                return false;
+            }
+            phy = p2.next();
+            if ( !isEqual( 0.48039661496919533, phy.getNode( "Diadocidia_spinosula" ).getDistanceToParent() ) ) {
+                return false;
+            }
+            if ( !isEqual( 0.3959796191512233, phy.getNode( "Diadocidia_stanfordensis" ).getDistanceToParent() ) ) {
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -6771,6 +8244,14 @@ public final class Test {
                     .equals( "Aranaeus" ) ) {
                 return false;
             }
+            phylogenies = factory.create( Test.PATH_TO_TEST_DATA + "S14117.nex", parser );
+            if ( phylogenies.length != 3 ) {
+                return false;
+            }
+            if ( !isEqual( phylogenies[ 2 ].getNode( "Aloysia lycioides 251-76-02169" ).getDistanceToParent(),
+                           0.00100049 ) ) {
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -6790,10 +8271,10 @@ public final class Test {
             nhxp.setTaxonomyExtraction( NHXParser.TAXONOMY_EXTRACTION.NO );
             nhxp.setReplaceUnderscores( true );
             final Phylogeny uc0 = factory.create( "(A__A_,_B_B)", nhxp )[ 0 ];
-            if ( !uc0.getRoot().getChildNode( 0 ).getName().equals( "A A " ) ) {
+            if ( !uc0.getRoot().getChildNode( 0 ).getName().equals( "A A" ) ) {
                 return false;
             }
-            if ( !uc0.getRoot().getChildNode( 1 ).getName().equals( " B B" ) ) {
+            if ( !uc0.getRoot().getChildNode( 1 ).getName().equals( "B B" ) ) {
                 return false;
             }
             final Phylogeny p1b = factory
@@ -6816,9 +8297,9 @@ public final class Test {
             final Phylogeny[] p11 = factory.create( "(A,B11);(C,D11) (E,F11)\t(G,H11)", new NHXParser() );
             final Phylogeny[] p12 = factory.create( "(A,B12) (C,D12) (E,F12) (G,H12)", new NHXParser() );
             final Phylogeny[] p13 = factory.create( " ; (;A; , ; B ; 1  3 ; \n)\t ( \n ;"
-                                                            + " C ; ,; D;13;);;;;;;(;E;,;F;13 ;) ; "
-                                                            + "; ; ( \t\n\r\b; G ;, ;H ;1 3; )  ;  ;   ;",
-                                                    new NHXParser() );
+                    + " C ; ,; D;13;);;;;;;(;E;,;F;13 ;) ; "
+                    + "; ; ( \t\n\r\b; G ;, ;H ;1 3; )  ;  ;   ;",
+                    new NHXParser() );
             if ( !p13[ 0 ].toNewHampshireX().equals( "(';A;',';B;13;')" ) ) {
                 return false;
             }
@@ -7084,14 +8565,14 @@ public final class Test {
             if ( p50.getNode( "A" ) == null ) {
                 return false;
             }
-            if ( !p50.toNewHampshire( false, NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS )
+            if ( !p50.toNewHampshire( NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS )
                     .equals( "((A,B)ab:2.0[88],C);" ) ) {
                 return false;
             }
-            if ( !p50.toNewHampshire( false, NH_CONVERSION_SUPPORT_VALUE_STYLE.NONE ).equals( "((A,B)ab:2.0,C);" ) ) {
+            if ( !p50.toNewHampshire( NH_CONVERSION_SUPPORT_VALUE_STYLE.NONE ).equals( "((A,B)ab:2.0,C);" ) ) {
                 return false;
             }
-            if ( !p50.toNewHampshire( false, NH_CONVERSION_SUPPORT_VALUE_STYLE.AS_INTERNAL_NODE_NAMES )
+            if ( !p50.toNewHampshire( NH_CONVERSION_SUPPORT_VALUE_STYLE.AS_INTERNAL_NODE_NAMES )
                     .equals( "((A,B)88:2.0,C);" ) ) {
                 return false;
             }
@@ -7109,13 +8590,63 @@ public final class Test {
             if ( p53.getNode( "B (x (a' ,b) f(x);" ) == null ) {
                 return false;
             }
-            // 
             final Phylogeny p54 = factory.create( new StringBuffer( "((A,B):[88],C)" ), new NHXParser() )[ 0 ];
             if ( p54.getNode( "A" ) == null ) {
                 return false;
             }
-            if ( !p54.toNewHampshire( false, NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS )
-                    .equals( "((A,B)[88],C);" ) ) {
+            if ( !p54.toNewHampshire( NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS ).equals( "((A,B)[88],C);" ) ) {
+                return false;
+            }
+            final Phylogeny p55 = factory
+                    .create( new StringBuffer( "((\"lcl|HPV32_L1.:1  s\":0.195593,\"lcl|HPV30_L1.1|;a\":0.114237):0.0359322,\"lcl|HPV56_L1.1|,d\":0.0727412,\"lcl|HPV66_L1.1x\":0.0798012);" ),
+                             new NHXParser() )[ 0 ];
+            if ( !p55
+                    .toNewHampshire()
+                    .equals( "(('lcl|HPV32_L1.:1 s':0.195593,'lcl|HPV30_L1.1|;a':0.114237):0.0359322,'lcl|HPV56_L1.1|,d':0.0727412,lcl|HPV66_L1.1x:0.0798012);" ) ) {
+                System.out.println( p55.toNewHampshire() );
+                return false;
+            }
+            final Phylogeny p56 = factory
+                    .create( new StringBuffer( "((\"lcl|HPV32_L1.:1      s\":0.195593,\"lcl|HPV30_L1.1|;a\":0.114\n237):0.0359322,\"lcl|HPV56_L1.1|,d\":0.0727412,\"lcl|HPV66_L1.1:x\":0.0798012);" ),
+                             new NHXParser() )[ 0 ];
+            if ( !p56
+                    .toNewHampshire()
+                    .equals( "(('lcl|HPV32_L1.:1 s':0.195593,'lcl|HPV30_L1.1|;a':0.114237):0.0359322,'lcl|HPV56_L1.1|,d':0.0727412,'lcl|HPV66_L1.1:x':0.0798012);" ) ) {
+                System.out.println( p56.toNewHampshire() );
+                return false;
+            }
+            final Phylogeny p57 = factory
+                    .create( new StringBuffer( "((\"lcl|HPV32_L1.:1      s\":0.195593,\"lcl|HPV30_L1.1|;a\":0.114\n237):0.0359322,\"lcl|HPV56_L1.1|,d\":0.0727412,\"lcl|HPV66_L1.1:x\":0.0798012);" ),
+                             new NHXParser() )[ 0 ];
+            if ( !p57
+                    .toNewHampshire()
+                    .equals( "(('lcl|HPV32_L1.:1 s':0.195593,'lcl|HPV30_L1.1|;a':0.114237):0.0359322,'lcl|HPV56_L1.1|,d':0.0727412,'lcl|HPV66_L1.1:x':0.0798012);" ) ) {
+                System.out.println( p56.toNewHampshire() );
+                return false;
+            }
+            final String s58 = "('Homo \"man\" sapiens:1',\"Homo 'man' sapiens;\")';root \"1_ )';";
+            final Phylogeny p58 = factory.create( new StringBuffer( s58 ), new NHXParser() )[ 0 ];
+            if ( !p58.toNewHampshire().equals( s58 ) ) {
+                System.out.println( p58.toNewHampshire() );
+                return false;
+            }
+            final String s59 = "('Homo \"man sapiens:1',\"Homo 'man sapiens\")\"root; '1_ )\";";
+            final Phylogeny p59 = factory.create( new StringBuffer( s59 ), new NHXParser() )[ 0 ];
+            if ( !p59.toNewHampshire().equals( s59 ) ) {
+                System.out.println( p59.toNewHampshire() );
+                return false;
+            }
+            final String s60 = "('\" ;,:\":\"',\"'abc def' g's_\",'=:0.45+,.:%~`!@#$%^&*()_-+={} | ;,');";
+            final Phylogeny p60 = factory.create( new StringBuffer( s60 ), new NHXParser() )[ 0 ];
+            if ( !p60.toNewHampshire().equals( s60 ) ) {
+                System.out.println( p60.toNewHampshire() );
+                return false;
+            }
+            final String s61 = "('H[omo] \"man\" sapiens:1',\"H[omo] 'man' sapiens;\",H[omo] sapiens)';root \"1_ )';";
+            final Phylogeny p61 = factory.create( new StringBuffer( s61 ), new NHXParser() )[ 0 ];
+            if ( !p61.toNewHampshire()
+                    .equals( "('H{omo} \"man\" sapiens:1',\"H{omo} 'man' sapiens;\",Hsapiens)';root \"1_ )';" ) ) {
+                System.out.println( p61.toNewHampshire() );
                 return false;
             }
         }
@@ -7456,56 +8987,117 @@ public final class Test {
             if ( !p8_0.toNewHampshire().equals( "((((A,B)ab,C)abc,D)abcd,E)abcde;" ) ) {
                 return false;
             }
-            if ( !p.hasNext() ) {
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            p8_1 = p.next();
+            if ( !p8_1.toNewHampshire().equals( "((((a,b)ab,c)abc,d)abcd,e)abcde;" ) ) {
+                return false;
+            }
+            if ( p.hasNext() ) {
+                return false;
+            }
+            if ( p.next() != null ) {
+                return false;
+            }
+            p.reset();
+            //
+            p.setSource( "" );
+            if ( p.hasNext() ) {
+                return false;
+            }
+            //
+            p.setSource( new File( Test.PATH_TO_TEST_DATA + "phylogeny27.nhx" ) );
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            Phylogeny p_27 = p.next();
+            if ( !p_27.toNewHampshireX().equals( "((((A,B)ab,C)abc,D)abcd,E)abcde" ) ) {
+                System.out.println( p_27.toNewHampshireX() );
+                System.exit( -1 );
+                return false;
+            }
+            if ( p.hasNext() ) {
+                return false;
+            }
+            if ( p.next() != null ) {
+                return false;
+            }
+            p.reset();
+            if ( !p.hasNext() ) {
+                return false;
+            }
+            p_27 = p.next();
+            if ( !p_27.toNewHampshireX().equals( "((((A,B)ab,C)abc,D)abcd,E)abcde" ) ) {
+                System.out.println( p_27.toNewHampshireX() );
+                System.exit( -1 );
+                return false;
+            }
+            if ( p.hasNext() ) {
+                return false;
+            }
+            if ( p.next() != null ) {
+                return false;
+            }
+            //
+            final String p30_str = "(A,B);(C,D)";
+            final NHXParser p30 = new NHXParser();
+            p30.setSource( p30_str );
+            if ( !p30.hasNext() ) {
+                return false;
+            }
+            Phylogeny phy30 = p30.next();
+            if ( !phy30.toNewHampshire().equals( "(A,B);" ) ) {
+                System.out.println( phy30.toNewHampshire() );
+                return false;
+            }
+            if ( !p30.hasNext() ) {
+                return false;
+            }
+            Phylogeny phy301 = p30.next();
+            if ( !phy301.toNewHampshire().equals( "(C,D);" ) ) {
+                System.out.println( phy301.toNewHampshire() );
                 return false;
             }
-            p8_1 = p.next();
-            if ( !p8_1.toNewHampshire().equals( "((((a,b)ab,c)abc,d)abcd,e)abcde;" ) ) {
+            if ( p30.hasNext() ) {
                 return false;
             }
-            if ( p.hasNext() ) {
+            if ( p30.hasNext() ) {
                 return false;
             }
-            if ( p.next() != null ) {
+            if ( p30.next() != null ) {
                 return false;
             }
-            p.reset();
-            //
-            p.setSource( "" );
-            if ( p.hasNext() ) {
+            if ( p30.next() != null ) {
                 return false;
             }
-            //
-            p.setSource( new File( Test.PATH_TO_TEST_DATA + "phylogeny27.nhx" ) );
-            if ( !p.hasNext() ) {
+            p30.reset();
+            if ( !p30.hasNext() ) {
                 return false;
             }
-            Phylogeny p_27 = p.next();
-            if ( !p_27.toNewHampshireX().equals( "((((A,B)ab,C)abc,D)abcd,E)abcde" ) ) {
-                System.out.println( p_27.toNewHampshireX() );
-                System.exit( -1 );
+            phy30 = p30.next();
+            if ( !phy30.toNewHampshire().equals( "(A,B);" ) ) {
+                System.out.println( phy30.toNewHampshire() );
                 return false;
             }
-            if ( p.hasNext() ) {
+            if ( !p30.hasNext() ) {
                 return false;
             }
-            if ( p.next() != null ) {
+            phy301 = p30.next();
+            if ( !phy301.toNewHampshire().equals( "(C,D);" ) ) {
+                System.out.println( phy301.toNewHampshire() );
                 return false;
             }
-            p.reset();
-            if ( !p.hasNext() ) {
+            if ( p30.hasNext() ) {
                 return false;
             }
-            p_27 = p.next();
-            if ( !p_27.toNewHampshireX().equals( "((((A,B)ab,C)abc,D)abcd,E)abcde" ) ) {
-                System.out.println( p_27.toNewHampshireX() );
-                System.exit( -1 );
+            if ( p30.hasNext() ) {
                 return false;
             }
-            if ( p.hasNext() ) {
+            if ( p30.next() != null ) {
                 return false;
             }
-            if ( p.next() != null ) {
+            if ( p30.next() != null ) {
                 return false;
             }
         }
@@ -7545,6 +9137,14 @@ public final class Test {
                 System.out.println( n6.toNewHampshireX() );
                 return false;
             }
+            final PhylogenyNode n7 = new PhylogenyNode();
+            n7.setName( "   gks:dr-m4 \"    '    `@:[]sadq04 " );
+            if ( !n7.toNewHampshire( true, PhylogenyNode.NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS )
+                    .equals( "'gks:dr-m4 \" ` `@:[]sadq04'" ) ) {
+                System.out.println( n7
+                                    .toNewHampshire( true, PhylogenyNode.NH_CONVERSION_SUPPORT_VALUE_STYLE.IN_SQUARE_BRACKETS ) );
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -7792,8 +9392,8 @@ public final class Test {
                 return false;
             }
             final PhylogenyNode n13 = PhylogenyNode
-                    .createInstanceFromNhxString( "blah_12345/1-2", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( !n13.getName().equals( "blah_12345/1-2" ) ) {
+                    .createInstanceFromNhxString( "BLAH_12345/1-2", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( !n13.getName().equals( "BLAH_12345/1-2" ) ) {
                 return false;
             }
             if ( PhylogenyMethods.getSpecies( n13 ).equals( "12345" ) ) {
@@ -7858,7 +9458,7 @@ public final class Test {
                 return false;
             }
             final PhylogenyNode n19 = PhylogenyNode
-                    .createInstanceFromNhxString( "blah_1-roejojoej", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+                    .createInstanceFromNhxString( "BLAH_1-roejojoej", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
             if ( !n19.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "1" ) ) {
                 return false;
             }
@@ -7866,7 +9466,7 @@ public final class Test {
                 return false;
             }
             final PhylogenyNode n30 = PhylogenyNode
-                    .createInstanceFromNhxString( "blah_1234567-roejojoej",
+                    .createInstanceFromNhxString( "BLAH_1234567-roejojoej",
                                                   NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
             if ( !n30.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "1234567" ) ) {
                 return false;
@@ -7875,7 +9475,7 @@ public final class Test {
                 return false;
             }
             final PhylogenyNode n31 = PhylogenyNode
-                    .createInstanceFromNhxString( "blah_12345678-roejojoej",
+                    .createInstanceFromNhxString( "BLAH_12345678-roejojoej",
                                                   NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
             if ( n31.getNodeData().isHasTaxonomy() ) {
                 return false;
@@ -7886,7 +9486,7 @@ public final class Test {
                 return false;
             }
             final PhylogenyNode n40 = PhylogenyNode
-                    .createInstanceFromNhxString( "bcl2_12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+                    .createInstanceFromNhxString( "BCL2_12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
             if ( !n40.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
                 return false;
             }
@@ -7981,6 +9581,17 @@ public final class Test {
             if ( !p10.toNewHampshireX().equals( "((A:0.2,B:0.3):0.5[&&NHX:B=91],C:0.1)root:0.1[&&NHX:B=100]" ) ) {
                 return false;
             }
+            final Phylogeny p11 = factory
+                    .create( " [79]   ( ('A: \" ' [co mment] :0 .2[comment],B:0.3[com])[com ment]: 0. 5 \t[ 9 1 ][ comment],C: 0.1)[comment]root:0.1[100] [comment]",
+                             new NHXParser() )[ 0 ];
+            if ( !p11.toNewHampshireX().equals( "(('A: \"':0.2,B:0.3):0.5[&&NHX:B=91],C:0.1)root:0.1[&&NHX:B=100]" ) ) {
+                return false;
+            }
+            final Phylogeny p12 = factory.create( "((A:0.2,B:0.3):0.5[&&NHX:B=91],C:0.1)root:0.1[&&NHX:B=100]",
+                                                  new NHXParser() )[ 0 ];
+            if ( !p12.toNewHampshireX().equals( "((A:0.2,B:0.3):0.5[&&NHX:B=91],C:0.1)root:0.1[&&NHX:B=100]" ) ) {
+                return false;
+            }
         }
         catch ( final Exception e ) {
             e.printStackTrace( System.out );
@@ -8019,15 +9630,15 @@ public final class Test {
             }
             final Phylogeny p2 = factory
                     .create( "(1[something_else(?)s,prob=0.9500000000000000e+00{}(((,p)rob_stddev=0.110000000000e+00,"
-                                     + "prob_range={1.000000000000000e+00,1.000000000000000e+00},prob(percent)=\"100\","
-                                     + "prob+-sd=\"100+-0\"]:4.129000000000000e-02[&length_mean=4.153987461671767e-02,"
-                                     + "length_median=4.129000000000000e-02,length_95%HPD={3.217800000000000e-02,"
-                                     + "5.026800000000000e-02}],2[&prob=0.810000000000000e+00,prob_stddev=0.000000000000000e+00,"
-                                     + "prob_range={1.000000000000000e+00,1.000000000000000e+00},prob(percent)=\"100\","
-                                     + "prob+-sd=\"100+-0\"]:6.375699999999999e-02[&length_mean=6.395210411945065e-02,"
-                                     + "length_median=6.375699999999999e-02,length_95%HPD={5.388600000000000e-02,"
-                                     + "7.369400000000000e-02}])",
-                             new NHXParser() )[ 0 ];
+                            + "prob_range={1.000000000000000e+00,1.000000000000000e+00},prob(percent)=\"100\","
+                            + "prob+-sd=\"100+-0\"]:4.129000000000000e-02[&length_mean=4.153987461671767e-02,"
+                            + "length_median=4.129000000000000e-02,length_95%HPD={3.217800000000000e-02,"
+                            + "5.026800000000000e-02}],2[&prob=0.810000000000000e+00,prob_stddev=0.000000000000000e+00,"
+                            + "prob_range={1.000000000000000e+00,1.000000000000000e+00},prob(percent)=\"100\","
+                            + "prob+-sd=\"100+-0\"]:6.375699999999999e-02[&length_mean=6.395210411945065e-02,"
+                            + "length_median=6.375699999999999e-02,length_95%HPD={5.388600000000000e-02,"
+                            + "7.369400000000000e-02}])",
+                            new NHXParser() )[ 0 ];
             if ( p2.getNode( "1" ) == null ) {
                 return false;
             }
@@ -8071,13 +9682,13 @@ public final class Test {
             if ( phy.getNodes( "'single quotes' inside double quotes" ).size() != 1 ) {
                 return false;
             }
-            if ( phy.getNodes( "double quotes inside single quotes" ).size() != 1 ) {
+            if ( phy.getNodes( "\"double quotes\" inside single quotes" ).size() != 1 ) {
                 return false;
             }
             if ( phy.getNodes( "noquotes" ).size() != 1 ) {
                 return false;
             }
-            if ( phy.getNodes( "A   (  B    C '" ).size() != 1 ) {
+            if ( phy.getNodes( "A ( B C '" ).size() != 1 ) {
                 return false;
             }
             final NHXParser p1p = new NHXParser();
@@ -8107,7 +9718,7 @@ public final class Test {
             final Phylogeny p10 = factory
                     .create( " [79]   ( (\"A \n\tB \" [co mment] :0 .2[comment],'B':0.3[com])[com ment]: 0. 5 \t[ 9 1 ][ comment],'C (or D?\\//;,))': 0.1)[comment]'\nroot is here (cool,  was! ) ':0.1[100] [comment]",
                              new NHXParser() )[ 0 ];
-            final String p10_clean_str = "(('A B':0.2,B:0.3):0.5[&&NHX:B=91],'C (or D?\\//;,))':0.1)'root is here (cool,  was! )':0.1[&&NHX:B=100]";
+            final String p10_clean_str = "(('A B':0.2,B:0.3):0.5[&&NHX:B=91],'C (or D?\\//;,))':0.1)'root is here (cool, was! )':0.1[&&NHX:B=100]";
             if ( !p10.toNewHampshireX().equals( p10_clean_str ) ) {
                 return false;
             }
@@ -8115,11 +9726,10 @@ public final class Test {
             if ( !p11.toNewHampshireX().equals( p10_clean_str ) ) {
                 return false;
             }
-            //
             final Phylogeny p12 = factory
                     .create( " [79]   ( (\"A \n\tB \" [[][] :0 .2[comment][\t&\t&\n N\tH\tX:S=mo\tnkey !],'\tB\t\b\t\n\f\rB B ':0.0\b3[])\t[com ment]: 0. 5 \t[ 9 1 ][ \ncomment],'C\t (or D?\\//;,))': 0.\b1)[comment]'\nroot \tis here (cool, \b\t\n\f\r was! ) ':0.1[100] [comment]",
                              new NHXParser() )[ 0 ];
-            final String p12_clean_str = "(('A B':0.2[&&NHX:S=monkey!],'BB B':0.03):0.5[&&NHX:B=91],'C (or D?\\//;,))':0.1)'root is here (cool,  was! )':0.1[&&NHX:B=100]";
+            final String p12_clean_str = "(('A B':0.2[&&NHX:S=monkey!],'BB B':0.03):0.5[&&NHX:B=91],'C (or D?\\//;,))':0.1)'root is here (cool, was! )':0.1[&&NHX:B=100]";
             if ( !p12.toNewHampshireX().equals( p12_clean_str ) ) {
                 return false;
             }
@@ -8127,7 +9737,7 @@ public final class Test {
             if ( !p13.toNewHampshireX().equals( p12_clean_str ) ) {
                 return false;
             }
-            final String p12_clean_str_nh = "(('A B':0.2,'BB B':0.03):0.5,'C (or D?\\//;,))':0.1)'root is here (cool,  was! )':0.1;";
+            final String p12_clean_str_nh = "(('A B':0.2,'BB B':0.03):0.5,'C (or D?\\//;,))':0.1)'root is here (cool, was! )':0.1;";
             if ( !p13.toNewHampshire().equals( p12_clean_str_nh ) ) {
                 return false;
             }
@@ -8222,7 +9832,7 @@ public final class Test {
                 // Do nothing -- means were not running from jar.
             }
             if ( xml_parser == null ) {
-                xml_parser = new PhyloXmlParser();
+                xml_parser = PhyloXmlParser.createPhyloXmlParser();
                 if ( USE_LOCAL_PHYLOXML_SCHEMA ) {
                     xml_parser.setValidateAgainstSchema( PHYLOXML_LOCAL_XSD );
                 }
@@ -9159,13 +10769,13 @@ public final class Test {
             // J. of Comput Bio. Vol. 4, No 2, pp.177-187
             final Phylogeny species6 = factory
                     .create( "(((1:[&&NHX:S=1],5:[&&NHX:S=5])1-5,((4:[&&NHX:S=4],6:[&&NHX:S=6])4-6,2:[&&NHX:S=2])4-6-2)1-5-4-6-2,"
-                                     + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
-                             new NHXParser() )[ 0 ];
+                            + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
+                            new NHXParser() )[ 0 ];
             final Phylogeny gene6 = factory
                     .create( "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1,3:0.1[&&NHX:S=3])1-2-3:0.1,"
-                                     + "((4:0.1[&&NHX:S=4],(5:0.1[&&NHX:S=5],6:0.1[&&NHX:S=6])5-6:0.1)4-5-6:0.1,"
-                                     + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],9:0.1[&&NHX:S=9])8-9:0.1)7-8-9:0.1)4-5-6-7-8-9:0.1)r;",
-                             new NHXParser() )[ 0 ];
+                            + "((4:0.1[&&NHX:S=4],(5:0.1[&&NHX:S=5],6:0.1[&&NHX:S=6])5-6:0.1)4-5-6:0.1,"
+                            + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],9:0.1[&&NHX:S=9])8-9:0.1)7-8-9:0.1)4-5-6-7-8-9:0.1)r;",
+                            new NHXParser() )[ 0 ];
             species6.setRooted( true );
             gene6.setRooted( true );
             final SDI sdi6 = new SDI( gene6, species6 );
@@ -9499,15 +11109,15 @@ public final class Test {
             }
             final Phylogeny species6 = factory
                     .create( "(((1:[&&NHX:S=1],5:[&&NHX:S=5])1-5,((4:[&&NHX:S=4],6:[&&NHX:S=6])4-6,2:[&&NHX:S=2])4-6-2)1-5-4-6-2,"
-                                     + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
-                             new NHXParser() )[ 0 ];
+                            + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
+                            new NHXParser() )[ 0 ];
             final Phylogeny gene6 = factory
                     .create( "((5:0.1[&&NHX:S=5],6:0.1[&&NHX:S=6])5-6:0.05[&&NHX:S=6],(4:0.1[&&NHX:S=4],"
-                                     + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
-                                     + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
-                                     + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
-                                     + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
-                             new NHXParser() )[ 0 ];
+                            + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
+                            + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
+                            + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
+                            + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
+                            new NHXParser() )[ 0 ];
             species6.setRooted( true );
             gene6.setRooted( true );
             Phylogeny[] p6 = sdi_unrooted.infer( gene6, species6, false, true, true, true, 10 );
@@ -9553,15 +11163,15 @@ public final class Test {
             p6 = null;
             final Phylogeny species7 = factory
                     .create( "(((1:[&&NHX:S=1],5:[&&NHX:S=5])1-5,((4:[&&NHX:S=4],6:[&&NHX:S=6])4-6,2:[&&NHX:S=2])4-6-2)1-5-4-6-2,"
-                                     + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
-                             new NHXParser() )[ 0 ];
+                            + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
+                            new NHXParser() )[ 0 ];
             final Phylogeny gene7 = factory
                     .create( "((5:0.1[&&NHX:S=5],6:0.1[&&NHX:S=6])5-6:0.05[&&NHX:S=6],(4:0.1[&&NHX:S=4],"
-                                     + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
-                                     + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
-                                     + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
-                                     + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
-                             new NHXParser() )[ 0 ];
+                            + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
+                            + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
+                            + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
+                            + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
+                            new NHXParser() )[ 0 ];
             species7.setRooted( true );
             gene7.setRooted( true );
             Phylogeny[] p7 = sdi_unrooted.infer( gene7, species7, true, true, true, true, 10 );
@@ -9607,15 +11217,15 @@ public final class Test {
             p7 = null;
             final Phylogeny species8 = factory
                     .create( "(((1:[&&NHX:S=1],5:[&&NHX:S=5])1-5,((4:[&&NHX:S=4],6:[&&NHX:S=6])4-6,2:[&&NHX:S=2])4-6-2)1-5-4-6-2,"
-                                     + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
-                             new NHXParser() )[ 0 ];
+                            + "((9:[&&NHX:S=9],3:[&&NHX:S=3])9-3,(8:[&&NHX:S=8],7:[&&NHX:S=7])8-7)9-3-8-7)",
+                            new NHXParser() )[ 0 ];
             final Phylogeny gene8 = factory
                     .create( "((5:0.1[&&NHX:S=5],6:0.1[&&NHX:S=6])5-6:0.05[&&NHX:S=6],(4:0.1[&&NHX:S=4],"
-                                     + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
-                                     + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
-                                     + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
-                                     + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
-                             new NHXParser() )[ 0 ];
+                            + "(((1:0.1[&&NHX:S=1],2:0.1[&&NHX:S=2])1-2:0.1[&&NHX:S=2],3:0.25[&&NHX:S=3])1-2-3:0.2[&&NHX:S=2],"
+                            + "(7:0.1[&&NHX:S=7],(8:0.1[&&NHX:S=8],"
+                            + "9:0.1[&&NHX:S=9])8-9:0.1[&&NHX:S=9])7-8-9:0.1[&&NHX:S=8])"
+                            + "4-5-6-7-8-9:0.1[&&NHX:S=5])4-5-6:0.05[&&NHX:S=5])",
+                            new NHXParser() )[ 0 ];
             species8.setRooted( true );
             gene8.setRooted( true );
             Phylogeny[] p8 = sdi_unrooted.infer( gene8, species8, false, false, true, true, 10 );
@@ -9667,6 +11277,190 @@ public final class Test {
         return true;
     }
 
+    private static boolean testSequenceDbWsTools1() {
+        try {
+            final PhylogenyNode n = new PhylogenyNode();
+            n.setName( "NP_001025424" );
+            Accession acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
+                    || !acc.getValue().equals( "NP_001025424" ) ) {
+                return false;
+            }
+            n.setName( "340 0559 -- _NP_001025424_dsfdg15 05" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
+                    || !acc.getValue().equals( "NP_001025424" ) ) {
+                return false;
+            }
+            n.setName( "NP_001025424.1" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
+                    || !acc.getValue().equals( "NP_001025424" ) ) {
+                return false;
+            }
+            n.setName( "NM_001030253" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
+                    || !acc.getValue().equals( "NM_001030253" ) ) {
+                return false;
+            }
+            n.setName( "BCL2_HUMAN" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
+                    || !acc.getValue().equals( "BCL2_HUMAN" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "P10415" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
+                    || !acc.getValue().equals( "P10415" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( " P10415 " );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
+                    || !acc.getValue().equals( "P10415" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "_P10415|" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
+                    || !acc.getValue().equals( "P10415" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "AY695820" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AY695820" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "_AY695820_" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AY695820" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "AAA59452" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AAA59452" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "_AAA59452_" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AAA59452" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "AAA59452.1" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AAA59452.1" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "_AAA59452.1_" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AAA59452.1" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "GI:94894583" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.GI.toString() )
+                    || !acc.getValue().equals( "94894583" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "gi|71845847|1,4-alpha-glucan branching enzyme [Dechloromonas aromatica RCB]" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.GI.toString() )
+                    || !acc.getValue().equals( "71845847" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+            n.setName( "gi|71845847|gb|AAZ45343.1| 1,4-alpha-glucan branching enzyme [Dechloromonas aromatica RCB]" );
+            acc = SequenceDbWsTools.obtainSeqAccession( n );
+            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
+                    || !acc.getValue().equals( "AAZ45343.1" ) ) {
+                System.out.println( acc.toString() );
+                return false;
+            }
+        }
+        catch ( final Exception e ) {
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testSequenceDbWsTools2() {
+        try {
+            final PhylogenyNode n1 = new PhylogenyNode( "NP_001025424" );
+            SequenceDbWsTools.obtainSeqInformation( n1 );
+            if ( !n1.getNodeData().getSequence().getName().equals( "Bcl2" ) ) {
+                return false;
+            }
+            if ( !n1.getNodeData().getTaxonomy().getScientificName().equals( "Danio rerio" ) ) {
+                return false;
+            }
+            if ( !n1.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+                return false;
+            }
+            if ( !n1.getNodeData().getSequence().getAccession().getValue().equals( "NP_001025424" ) ) {
+                return false;
+            }
+            final PhylogenyNode n2 = new PhylogenyNode( "NM_001030253" );
+            SequenceDbWsTools.obtainSeqInformation( n2 );
+            if ( !n2.getNodeData().getSequence().getName().equals( "Danio rerio B-cell CLL/lymphoma 2a (bcl2a), mRNA" ) ) {
+                return false;
+            }
+            if ( !n2.getNodeData().getTaxonomy().getScientificName().equals( "Danio rerio" ) ) {
+                return false;
+            }
+            if ( !n2.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+                return false;
+            }
+            if ( !n2.getNodeData().getSequence().getAccession().getValue().equals( "NM_001030253" ) ) {
+                return false;
+            }
+            final PhylogenyNode n3 = new PhylogenyNode( "NM_184234.2" );
+            SequenceDbWsTools.obtainSeqInformation( n3 );
+            if ( !n3.getNodeData().getSequence().getName()
+                    .equals( "Homo sapiens RNA binding motif protein 39 (RBM39), transcript variant 1, mRNA" ) ) {
+                return false;
+            }
+            if ( !n3.getNodeData().getTaxonomy().getScientificName().equals( "Homo sapiens" ) ) {
+                return false;
+            }
+            if ( !n3.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+                return false;
+            }
+            if ( !n3.getNodeData().getSequence().getAccession().getValue().equals( "NM_184234" ) ) {
+                return false;
+            }
+        }
+        catch ( final IOException e ) {
+            System.out.println();
+            System.out.println( "the following might be due to absence internet connection:" );
+            e.printStackTrace( System.out );
+            return true;
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
     private static boolean testSequenceIdParsing() {
         try {
             Accession id = SequenceAccessionTools.parseAccessorFromString( "gb_ADF31344_segmented_worms_" );
@@ -9678,7 +11472,6 @@ public final class Test {
                 }
                 return false;
             }
-            //
             id = SequenceAccessionTools.parseAccessorFromString( "segmented worms|gb_ADF31344" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "ADF31344" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9688,7 +11481,6 @@ public final class Test {
                 }
                 return false;
             }
-            //
             id = SequenceAccessionTools.parseAccessorFromString( "segmented worms gb_ADF31344 and more" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "ADF31344" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9698,7 +11490,6 @@ public final class Test {
                 }
                 return false;
             }
-            // 
             id = SequenceAccessionTools.parseAccessorFromString( "gb_AAA96518_1" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "AAA96518" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9708,7 +11499,6 @@ public final class Test {
                 }
                 return false;
             }
-            // 
             id = SequenceAccessionTools.parseAccessorFromString( "gb_EHB07727_1_rodents_" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "EHB07727" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9718,7 +11508,6 @@ public final class Test {
                 }
                 return false;
             }
-            // 
             id = SequenceAccessionTools.parseAccessorFromString( "dbj_BAF37827_1_turtles_" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "BAF37827" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9728,7 +11517,6 @@ public final class Test {
                 }
                 return false;
             }
-            // 
             id = SequenceAccessionTools.parseAccessorFromString( "emb_CAA73223_1_primates_" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
                     || !id.getValue().equals( "CAA73223" ) || !id.getSource().equals( "ncbi" ) ) {
@@ -9738,37 +11526,67 @@ public final class Test {
                 }
                 return false;
             }
-            // 
-            id = SequenceAccessionTools.parseAccessorFromString( "mites|ref_XP_002434188_1" );
+            id = SequenceAccessionTools.parseAccessorFromString( "mites|ref_XP_002434188_1" );
+            if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
+                    || !id.getValue().equals( "XP_002434188" ) || !id.getSource().equals( "refseq" ) ) {
+                if ( id != null ) {
+                    System.out.println( "value   =" + id.getValue() );
+                    System.out.println( "provider=" + id.getSource() );
+                }
+                return false;
+            }
+            id = SequenceAccessionTools.parseAccessorFromString( "mites_ref_XP_002434188_1_bla_XP_12345" );
+            if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
+                    || !id.getValue().equals( "XP_002434188" ) || !id.getSource().equals( "refseq" ) ) {
+                if ( id != null ) {
+                    System.out.println( "value   =" + id.getValue() );
+                    System.out.println( "provider=" + id.getSource() );
+                }
+                return false;
+            }
+            id = SequenceAccessionTools.parseAccessorFromString( "P4A123" );
+            if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
+                    || !id.getValue().equals( "P4A123" ) || !id.getSource().equals( "uniprot" ) ) {
+                if ( id != null ) {
+                    System.out.println( "value   =" + id.getValue() );
+                    System.out.println( "provider=" + id.getSource() );
+                }
+                return false;
+            }
+            id = SequenceAccessionTools.parseAccessorFromString( "XP_12345" );
+            if ( id != null ) {
+                System.out.println( "value   =" + id.getValue() );
+                System.out.println( "provider=" + id.getSource() );
+                return false;
+            }
+            id = SequenceAccessionTools.parseAccessorFromString( "N3B004Z009" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
-                    || !id.getValue().equals( "XP_002434188" ) || !id.getSource().equals( "refseq" ) ) {
+                    || !id.getValue().equals( "N3B004Z009" ) || !id.getSource().equals( "uniprot" ) ) {
                 if ( id != null ) {
                     System.out.println( "value   =" + id.getValue() );
                     System.out.println( "provider=" + id.getSource() );
                 }
                 return false;
             }
-            // 
-            id = SequenceAccessionTools.parseAccessorFromString( "mites_ref_XP_002434188_1_bla_XP_12345" );
+            id = SequenceAccessionTools.parseAccessorFromString( "A4CAA4ZBB9" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
-                    || !id.getValue().equals( "XP_002434188" ) || !id.getSource().equals( "refseq" ) ) {
+                    || !id.getValue().equals( "A4CAA4ZBB9" ) || !id.getSource().equals( "uniprot" ) ) {
                 if ( id != null ) {
                     System.out.println( "value   =" + id.getValue() );
                     System.out.println( "provider=" + id.getSource() );
                 }
                 return false;
             }
-            // 
-            id = SequenceAccessionTools.parseAccessorFromString( "P4A123" );
+            id = SequenceAccessionTools.parseAccessorFromString( "ecoli_A4CAA4ZBB9_rt" );
             if ( ( id == null ) || ForesterUtil.isEmpty( id.getValue() ) || ForesterUtil.isEmpty( id.getSource() )
-                    || !id.getValue().equals( "P4A123" ) || !id.getSource().equals( "uniprot" ) ) {
+                    || !id.getValue().equals( "A4CAA4ZBB9" ) || !id.getSource().equals( "uniprot" ) ) {
                 if ( id != null ) {
                     System.out.println( "value   =" + id.getValue() );
                     System.out.println( "provider=" + id.getSource() );
                 }
                 return false;
             }
-            id = SequenceAccessionTools.parseAccessorFromString( "XP_12345" );
+            id = SequenceAccessionTools.parseAccessorFromString( "Q4CAA4ZBB9" );
             if ( id != null ) {
                 System.out.println( "value   =" + id.getValue() );
                 System.out.println( "provider=" + id.getSource() );
@@ -9945,14 +11763,12 @@ public final class Test {
             if ( !s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "G" ) );
             if ( !s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "E" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "D" ) );
@@ -9962,7 +11778,6 @@ public final class Test {
             if ( !s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "G" ) );
@@ -9970,7 +11785,6 @@ public final class Test {
             if ( !s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "G" ) );
@@ -9979,14 +11793,12 @@ public final class Test {
             if ( !s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "E" ) );
@@ -9995,7 +11807,6 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "G" ) );
@@ -10005,7 +11816,6 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "B" ) );
@@ -10013,49 +11823,42 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "D" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "B" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "C" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "E" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "G" ) );
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "F" ) );
@@ -10063,7 +11866,6 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "A" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "B" ) );
@@ -10071,7 +11873,6 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "E" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "D" ) );
@@ -10079,7 +11880,6 @@ public final class Test {
             if ( s0.match( query_nodes ) ) {
                 return false;
             }
-            //
             query_nodes = new HashSet<PhylogenyNode>();
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "E" ) );
             query_nodes.add( PhylogenyNode.createInstanceFromNhxString( "D" ) );
@@ -10568,24 +12368,24 @@ public final class Test {
             final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
             final Phylogeny t0_1 = factory.create( "(((A,B),C),(D,E))", new NHXParser() )[ 0 ];
             final Phylogeny[] phylogenies_1 = factory.create( "(((A,B),C),(D,E)) " + "(((C,B),A),(D,E))"
-                                                                      + "(((A,B),C),(D,E)) " + "(((A,B),C),(D,E))"
-                                                                      + "(((A,B),C),(D,E))" + "(((C,B),A),(D,E))"
-                                                                      + "(((E,B),D),(C,A))" + "(((C,B),A),(D,E))"
-                                                                      + "(((A,B),C),(D,E))" + "(((A,B),C),(D,E))",
-                                                              new NHXParser() );
+                    + "(((A,B),C),(D,E)) " + "(((A,B),C),(D,E))"
+                    + "(((A,B),C),(D,E))" + "(((C,B),A),(D,E))"
+                    + "(((E,B),D),(C,A))" + "(((C,B),A),(D,E))"
+                    + "(((A,B),C),(D,E))" + "(((A,B),C),(D,E))",
+                    new NHXParser() );
             SupportCount.count( t0_1, phylogenies_1, true, false );
             final Phylogeny t0_2 = factory.create( "(((((A,B),C),D),E),(F,G))", new NHXParser() )[ 0 ];
             final Phylogeny[] phylogenies_2 = factory.create( "(((((A,B),C),D),E),(F,G))"
-                                                                      + "(((((A,B),C),D),E),((F,G),X))"
-                                                                      + "(((((A,Y),B),C),D),((F,G),E))"
-                                                                      + "(((((A,B),C),D),E),(F,G))"
-                                                                      + "(((((A,B),C),D),E),(F,G))"
-                                                                      + "(((((A,B),C),D),E),(F,G))"
-                                                                      + "(((((A,B),C),D),E),(F,G),Z)"
-                                                                      + "(((((A,B),C),D),E),(F,G))"
-                                                                      + "((((((A,B),C),D),E),F),G)"
-                                                                      + "(((((X,Y),F,G),E),((A,B),C)),D)",
-                                                              new NHXParser() );
+                    + "(((((A,B),C),D),E),((F,G),X))"
+                    + "(((((A,Y),B),C),D),((F,G),E))"
+                    + "(((((A,B),C),D),E),(F,G))"
+                    + "(((((A,B),C),D),E),(F,G))"
+                    + "(((((A,B),C),D),E),(F,G))"
+                    + "(((((A,B),C),D),E),(F,G),Z)"
+                    + "(((((A,B),C),D),E),(F,G))"
+                    + "((((((A,B),C),D),E),F),G)"
+                    + "(((((X,Y),F,G),E),((A,B),C)),D)",
+                    new NHXParser() );
             SupportCount.count( t0_2, phylogenies_2, true, false );
             final PhylogenyNodeIterator it = t0_2.iteratorPostorder();
             while ( it.hasNext() ) {
@@ -10719,472 +12519,277 @@ public final class Test {
             }
             if ( p2.getNode( "hi" ).getDistanceToParent() != 0.59 ) {
                 return false;
-            }
-            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "ab" ) ) != 97 ) {
-                return false;
-            }
-            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "abc" ) ) != 57 ) {
-                return false;
-            }
-            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "de" ) ) != 10 ) {
-                return false;
-            }
-            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "fg" ) ) != 50 ) {
-                return false;
-            }
-            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "hi" ) ) != 64 ) {
-                return false;
-            }
-        }
-        catch ( final Exception e ) {
-            e.printStackTrace( System.out );
-            return false;
-        }
-        return true;
-    }
-
-    private static boolean testTaxonomyExtraction() {
-        try {
-            final PhylogenyNode n0 = PhylogenyNode
-                    .createInstanceFromNhxString( "sd_12345678", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n0.getNodeData().isHasTaxonomy() ) {
-                return false;
-            }
-            final PhylogenyNode n1 = PhylogenyNode
-                    .createInstanceFromNhxString( "sd_12345x", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n1.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n1.toString() );
-                return false;
-            }
-            final PhylogenyNode n2x = PhylogenyNode
-                    .createInstanceFromNhxString( "12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n2x.getNodeData().isHasTaxonomy() ) {
-                return false;
-            }
-            final PhylogenyNode n3 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( !n3.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
-                System.out.println( n3.toString() );
-                return false;
-            }
-            final PhylogenyNode n4 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag-12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n4.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n4.toString() );
-                return false;
-            }
-            final PhylogenyNode n5 = PhylogenyNode
-                    .createInstanceFromNhxString( "12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n5.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n5.toString() );
-                return false;
-            }
-            final PhylogenyNode n6 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag-12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n6.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n6.toString() );
-                return false;
-            }
-            final PhylogenyNode n7 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag-12345_blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n7.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n7.toString() );
-                return false;
-            }
-            final PhylogenyNode n8 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( !n8.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
-                System.out.println( n8.toString() );
-                return false;
-            }
-            final PhylogenyNode n9 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_12345/blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( !n9.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
-                System.out.println( n9.toString() );
-                return false;
-            }
-            final PhylogenyNode n10x = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_12X45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n10x.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n10x.toString() );
-                return false;
-            }
-            final PhylogenyNode n10xx = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_1YX45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( n10xx.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n10xx.toString() );
-                return false;
-            }
-            final PhylogenyNode n10 = PhylogenyNode
-                    .createInstanceFromNhxString( "blag_9YX45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
-            if ( !n10.getNodeData().getTaxonomy().getTaxonomyCode().equals( "9YX45" ) ) {
-                System.out.println( n10.toString() );
-                return false;
-            }
-            final PhylogenyNode n11 = PhylogenyNode
-                    .createInstanceFromNhxString( "BLAG_Mus_musculus", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
-            if ( !n11.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
-                System.out.println( n11.toString() );
-                return false;
-            }
-            final PhylogenyNode n12 = PhylogenyNode
-                    .createInstanceFromNhxString( "BLAG_Mus_musculus_musculus",
-                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
-            if ( !n12.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
-                System.out.println( n12.toString() );
-                return false;
-            }
-            final PhylogenyNode n13 = PhylogenyNode
-                    .createInstanceFromNhxString( "BLAG_Mus_musculus1", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
-            if ( n13.getNodeData().isHasTaxonomy() ) {
-                System.out.println( n13.toString() );
-                return false;
-            }
-        }
-        catch ( final Exception e ) {
-            e.printStackTrace( System.out );
-            return false;
-        }
-        return true;
-    }
-
-    private static boolean testTreeMethods() {
-        try {
-            final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
-            final Phylogeny t0 = factory.create( "((((A,B)ab,C)abc,D)abcd,E)", new NHXParser() )[ 0 ];
-            PhylogenyMethods.collapseSubtreeStructure( t0.getNode( "abcd" ) );
-            if ( !t0.toNewHampshireX().equals( "((A,B,C,D)abcd,E)" ) ) {
-                System.out.println( t0.toNewHampshireX() );
-                return false;
-            }
-            final Phylogeny t1 = factory.create( "((((A:0.1,B)ab:0.2,C)abc:0.3,D)abcd:0.4,E)", new NHXParser() )[ 0 ];
-            PhylogenyMethods.collapseSubtreeStructure( t1.getNode( "abcd" ) );
-            if ( !isEqual( t1.getNode( "A" ).getDistanceToParent(), 0.6 ) ) {
-                return false;
-            }
-            if ( !isEqual( t1.getNode( "B" ).getDistanceToParent(), 0.5 ) ) {
-                return false;
-            }
-            if ( !isEqual( t1.getNode( "C" ).getDistanceToParent(), 0.3 ) ) {
-                return false;
-            }
-        }
-        catch ( final Exception e ) {
-            e.printStackTrace( System.out );
-            return false;
-        }
-        return true;
-    }
-
-    private static boolean testSequenceDbWsTools1() {
-        try {
-            final PhylogenyNode n = new PhylogenyNode();
-            n.setName( "NP_001025424" );
-            Accession acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
-                    || !acc.getValue().equals( "NP_001025424" ) ) {
-                return false;
-            }
-            n.setName( "340 0559 -- _NP_001025424_dsfdg15 05" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
-                    || !acc.getValue().equals( "NP_001025424" ) ) {
-                return false;
-            }
-            n.setName( "NP_001025424.1" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
-                    || !acc.getValue().equals( "NP_001025424" ) ) {
-                return false;
-            }
-            n.setName( "NM_001030253" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.REFSEQ.toString() )
-                    || !acc.getValue().equals( "NM_001030253" ) ) {
-                return false;
-            }
-            n.setName( "BCL2_HUMAN" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
-                    || !acc.getValue().equals( "BCL2_HUMAN" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "P10415" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
-                    || !acc.getValue().equals( "P10415" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( " P10415 " );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
-                    || !acc.getValue().equals( "P10415" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "_P10415|" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.UNIPROT.toString() )
-                    || !acc.getValue().equals( "P10415" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "AY695820" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AY695820" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "_AY695820_" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AY695820" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "AAA59452" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AAA59452" ) ) {
-                System.out.println( acc.toString() );
-                return false;
-            }
-            n.setName( "_AAA59452_" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AAA59452" ) ) {
-                System.out.println( acc.toString() );
+            }
+            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "ab" ) ) != 97 ) {
                 return false;
             }
-            n.setName( "AAA59452.1" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AAA59452.1" ) ) {
-                System.out.println( acc.toString() );
+            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "abc" ) ) != 57 ) {
                 return false;
             }
-            n.setName( "_AAA59452.1_" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.NCBI.toString() )
-                    || !acc.getValue().equals( "AAA59452.1" ) ) {
-                System.out.println( acc.toString() );
+            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "de" ) ) != 10 ) {
                 return false;
             }
-            n.setName( "GI:94894583" );
-            acc = SequenceDbWsTools.obtainSeqAccession( n );
-            if ( ( acc == null ) || !acc.getSource().equals( Source.GI.toString() )
-                    || !acc.getValue().equals( "94894583" ) ) {
-                System.out.println( acc.toString() );
+            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "fg" ) ) != 50 ) {
+                return false;
+            }
+            if ( PhylogenyMethods.getConfidenceValue( p2.getNode( "hi" ) ) != 64 ) {
                 return false;
             }
         }
         catch ( final Exception e ) {
+            e.printStackTrace( System.out );
             return false;
         }
         return true;
     }
 
-    private static boolean testSequenceDbWsTools2() {
+    private static boolean testTaxonomyExtraction() {
         try {
-            final PhylogenyNode n1 = new PhylogenyNode( "NP_001025424" );
-            SequenceDbWsTools.obtainSeqInformation( n1 );
-            if ( !n1.getNodeData().getSequence().getName().equals( "Bcl2" ) ) {
+            final PhylogenyNode n0 = PhylogenyNode
+                    .createInstanceFromNhxString( "sd_12345678", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n0.getNodeData().isHasTaxonomy() ) {
                 return false;
             }
-            if ( !n1.getNodeData().getTaxonomy().getScientificName().equals( "Danio rerio" ) ) {
+            final PhylogenyNode n1 = PhylogenyNode
+                    .createInstanceFromNhxString( "sd_12345x", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n1.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n1.toString() );
                 return false;
             }
-            if ( !n1.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+            final PhylogenyNode n2x = PhylogenyNode
+                    .createInstanceFromNhxString( "12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n2x.getNodeData().isHasTaxonomy() ) {
                 return false;
             }
-            if ( !n1.getNodeData().getSequence().getAccession().getValue().equals( "NP_001025424" ) ) {
+            final PhylogenyNode n3 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( !n3.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
+                System.out.println( n3.toString() );
                 return false;
             }
-            final PhylogenyNode n2 = new PhylogenyNode( "NM_001030253" );
-            SequenceDbWsTools.obtainSeqInformation( n2 );
-            System.out.println( n2.toString() );
-            if ( !n2.getNodeData().getSequence().getName()
-                    .equals( "Danio rerio B-cell leukemia/lymphoma 2 (bcl2), mRNA" ) ) {
+            final PhylogenyNode n4 = PhylogenyNode
+                    .createInstanceFromNhxString( "blag-12345", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n4.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n4.toString() );
                 return false;
             }
-            if ( !n2.getNodeData().getTaxonomy().getScientificName().equals( "Danio rerio" ) ) {
+            final PhylogenyNode n5 = PhylogenyNode
+                    .createInstanceFromNhxString( "12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n5.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n5.toString() );
                 return false;
             }
-            if ( !n2.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+            final PhylogenyNode n6 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG-12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n6.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n6.toString() );
                 return false;
             }
-            if ( !n2.getNodeData().getSequence().getAccession().getValue().equals( "NM_001030253" ) ) {
+            final PhylogenyNode n7 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG-12345_blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n7.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n7.toString() );
                 return false;
             }
-            final PhylogenyNode n3 = new PhylogenyNode( "NM_184234.2" );
-            SequenceDbWsTools.obtainSeqInformation( n3 );
-            System.out.println( "n=" + n3.toString() );
-            if ( !n3.getNodeData().getSequence().getName()
-                    .equals( "Homo sapiens RNA binding motif protein 39 (RBM39), transcript variant 1, mRNA" ) ) {
+            final PhylogenyNode n8 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_12345-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( !n8.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
+                System.out.println( n8.toString() );
                 return false;
             }
-            if ( !n3.getNodeData().getTaxonomy().getScientificName().equals( "Homo sapiens" ) ) {
+            final PhylogenyNode n9 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_12345/blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( !n9.getNodeData().getTaxonomy().getIdentifier().getValue().equals( "12345" ) ) {
+                System.out.println( n9.toString() );
                 return false;
             }
-            if ( !n3.getNodeData().getSequence().getAccession().getSource().equals( Source.REFSEQ.toString() ) ) {
+            final PhylogenyNode n10x = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_12X45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n10x.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n10x.toString() );
                 return false;
             }
-            if ( !n3.getNodeData().getSequence().getAccession().getValue().equals( "NM_184234" ) ) {
+            final PhylogenyNode n10xx = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_1YX45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( n10xx.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n10xx.toString() );
                 return false;
             }
-        }
-        catch ( final IOException e ) {
-            System.out.println();
-            System.out.println( "the following might be due to absence internet connection:" );
-            e.printStackTrace( System.out );
-            return true;
-        }
-        catch ( final Exception e ) {
-            e.printStackTrace();
-            return false;
-        }
-        return true;
-    }
-
-    private static boolean testEbiEntryRetrieval() {
-        try {
-            final SequenceDatabaseEntry entry = SequenceDbWsTools.obtainEntry( "AAK41263" );
-            if ( !entry.getAccession().equals( "AAK41263" ) ) {
-                System.out.println( entry.getAccession() );
+            final PhylogenyNode n10 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_9YX45-blag", NHXParser.TAXONOMY_EXTRACTION.PFAM_STYLE_RELAXED );
+            if ( !n10.getNodeData().getTaxonomy().getTaxonomyCode().equals( "9YX45" ) ) {
+                System.out.println( n10.toString() );
                 return false;
             }
-            if ( !entry.getTaxonomyScientificName().equals( "Sulfolobus solfataricus P2" ) ) {
-                System.out.println( entry.getTaxonomyScientificName() );
+            final PhylogenyNode n11 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_Mus_musculus", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n11.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
+                System.out.println( n11.toString() );
                 return false;
             }
-            if ( !entry.getSequenceName()
-                    .equals( "Sulfolobus solfataricus P2 Glycogen debranching enzyme, hypothetical (treX-like)" ) ) {
-                System.out.println( entry.getSequenceName() );
+            final PhylogenyNode n12 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_Mus_musculus_musculus",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n12.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
+                System.out.println( n12.toString() );
                 return false;
             }
-            // if ( !entry.getSequenceSymbol().equals( "" ) ) {
-            //     System.out.println( entry.getSequenceSymbol() );
-            //     return false;
-            // }
-            if ( !entry.getGeneName().equals( "treX-like" ) ) {
-                System.out.println( entry.getGeneName() );
+            final PhylogenyNode n13 = PhylogenyNode
+                    .createInstanceFromNhxString( "BLAG_Mus_musculus1", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( n13.getNodeData().isHasTaxonomy() ) {
+                System.out.println( n13.toString() );
                 return false;
             }
-            if ( !entry.getTaxonomyIdentifier().equals( "273057" ) ) {
-                System.out.println( entry.getTaxonomyIdentifier() );
+            final PhylogenyNode n14 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus_musculus_392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n14.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
+                System.out.println( n14.toString() );
                 return false;
             }
-            if ( !entry.getAnnotations().first().getRefValue().equals( "3.2.1.33" ) ) {
-                System.out.println( entry.getAnnotations().first().getRefValue() );
+            final PhylogenyNode n15 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus_musculus_K392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n15.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
+                System.out.println( n15.toString() );
                 return false;
             }
-            if ( !entry.getAnnotations().first().getRefSource().equals( "EC" ) ) {
-                System.out.println( entry.getAnnotations().first().getRefSource() );
+            final PhylogenyNode n16 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus musculus 392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n16.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
+                System.out.println( n16.toString() );
                 return false;
             }
-            if ( entry.getCrossReferences().size() != 5 ) {
+            final PhylogenyNode n17 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus musculus K392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n17.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus" ) ) {
+                System.out.println( n17.toString() );
                 return false;
             }
-            //
-            final SequenceDatabaseEntry entry1 = SequenceDbWsTools.obtainEntry( "ABJ16409" );
-            if ( !entry1.getAccession().equals( "ABJ16409" ) ) {
+            final PhylogenyNode n18 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus_musculus_musculus_392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n18.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
+                System.out.println( n18.toString() );
                 return false;
             }
-            if ( !entry1.getTaxonomyScientificName().equals( "Felis catus" ) ) {
-                System.out.println( entry1.getTaxonomyScientificName() );
+            final PhylogenyNode n19 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus_musculus_musculus_K392",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n19.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
+                System.out.println( n19.toString() );
                 return false;
             }
-            if ( !entry1.getSequenceName().equals( "Felis catus (domestic cat) partial BCL2" ) ) {
-                System.out.println( entry1.getSequenceName() );
+            final PhylogenyNode n20 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus musculus musculus 392", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n20.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
+                System.out.println( n20.toString() );
                 return false;
             }
-            if ( !entry1.getTaxonomyIdentifier().equals( "9685" ) ) {
-                System.out.println( entry1.getTaxonomyIdentifier() );
+            final PhylogenyNode n21 = PhylogenyNode
+                    .createInstanceFromNhxString( "Mus musculus musculus K392",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n21.getNodeData().getTaxonomy().getScientificName().equals( "Mus musculus musculus" ) ) {
+                System.out.println( n21.toString() );
                 return false;
             }
-            if ( !entry1.getGeneName().equals( "BCL2" ) ) {
-                System.out.println( entry1.getGeneName() );
+            final PhylogenyNode n23 = PhylogenyNode
+                    .createInstanceFromNhxString( "9EMVE_Nematostella_vectensis",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n23.getNodeData().getTaxonomy().getScientificName().equals( "Nematostella vectensis" ) ) {
+                System.out.println( n23.toString() );
                 return false;
             }
-            if ( entry1.getCrossReferences().size() != 6 ) {
+            final PhylogenyNode n24 = PhylogenyNode
+                    .createInstanceFromNhxString( "9EMVE_Nematostella", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n24.getNodeData().getTaxonomy().getTaxonomyCode().equals( "9EMVE" ) ) {
+                System.out.println( n24.toString() );
                 return false;
             }
             //
-            final SequenceDatabaseEntry entry2 = SequenceDbWsTools.obtainEntry( "NM_184234" );
-            if ( !entry2.getAccession().equals( "NM_184234" ) ) {
-                return false;
-            }
-            if ( !entry2.getTaxonomyScientificName().equals( "Homo sapiens" ) ) {
-                System.out.println( entry2.getTaxonomyScientificName() );
-                return false;
-            }
-            if ( !entry2.getSequenceName()
-                    .equals( "Homo sapiens RNA binding motif protein 39 (RBM39), transcript variant 1, mRNA" ) ) {
-                System.out.println( entry2.getSequenceName() );
+            final PhylogenyNode n25 = PhylogenyNode
+                    .createInstanceFromNhxString( "Nematostella_vectensis_NEMVE",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n25.getNodeData().getTaxonomy().getTaxonomyCode().equals( "NEMVE" ) ) {
+                System.out.println( n25.toString() );
                 return false;
             }
-            if ( !entry2.getTaxonomyIdentifier().equals( "9606" ) ) {
-                System.out.println( entry2.getTaxonomyIdentifier() );
+            final PhylogenyNode n26 = PhylogenyNode
+                    .createInstanceFromNhxString( "Nematostella_vectensis_9EMVE",
+                                                  NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n26.getNodeData().getTaxonomy().getScientificName().equals( "Nematostella vectensis" ) ) {
+                System.out.println( n26.toString() );
                 return false;
             }
-            if ( !entry2.getGeneName().equals( "RBM39" ) ) {
-                System.out.println( entry2.getGeneName() );
+            final PhylogenyNode n27 = PhylogenyNode
+                    .createInstanceFromNhxString( "Nematostella_9EMVE", NHXParser.TAXONOMY_EXTRACTION.AGGRESSIVE );
+            if ( !n27.getNodeData().getTaxonomy().getTaxonomyCode().equals( "9EMVE" ) ) {
+                System.out.println( n27.toString() );
                 return false;
             }
-            if ( entry2.getCrossReferences().size() != 3 ) {
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace( System.out );
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testTreeCopy() {
+        try {
+            final String str_0 = "((((a,b),c),d)[&&NHX:S=lizards],e[&&NHX:S=reptiles])r[&&NHX:S=animals]";
+            final Phylogeny t0 = Phylogeny.createInstanceFromNhxString( str_0 );
+            final Phylogeny t1 = t0.copy();
+            if ( !t1.toNewHampshireX().equals( t0.toNewHampshireX() ) ) {
                 return false;
             }
-            //
-            final SequenceDatabaseEntry entry3 = SequenceDbWsTools.obtainEntry( "HM043801" );
-            if ( !entry3.getAccession().equals( "HM043801" ) ) {
+            if ( !t1.toNewHampshireX().equals( str_0 ) ) {
                 return false;
             }
-            if ( !entry3.getTaxonomyScientificName().equals( "Bursaphelenchus xylophilus" ) ) {
-                System.out.println( entry3.getTaxonomyScientificName() );
+            t0.deleteSubtree( t0.getNode( "c" ), true );
+            t0.deleteSubtree( t0.getNode( "a" ), true );
+            t0.getRoot().getNodeData().getTaxonomy().setScientificName( "metazoa" );
+            t0.getNode( "b" ).setName( "Bee" );
+            if ( !t0.toNewHampshireX().equals( "((Bee,d)[&&NHX:S=lizards],e[&&NHX:S=reptiles])r[&&NHX:S=metazoa]" ) ) {
                 return false;
             }
-            if ( !entry3.getSequenceName().equals( "Bursaphelenchus xylophilus RAF gene, complete cds" ) ) {
-                System.out.println( entry3.getSequenceName() );
+            if ( !t1.toNewHampshireX().equals( str_0 ) ) {
                 return false;
             }
-            if ( !entry3.getTaxonomyIdentifier().equals( "6326" ) ) {
-                System.out.println( entry3.getTaxonomyIdentifier() );
+            t0.deleteSubtree( t0.getNode( "e" ), true );
+            t0.deleteSubtree( t0.getNode( "Bee" ), true );
+            t0.deleteSubtree( t0.getNode( "d" ), true );
+            if ( !t1.toNewHampshireX().equals( str_0 ) ) {
                 return false;
             }
-            if ( !entry3.getSequenceSymbol().equals( "RAF" ) ) {
-                System.out.println( entry3.getSequenceSymbol() );
+        }
+        catch ( final Exception e ) {
+            e.printStackTrace();
+            return false;
+        }
+        return true;
+    }
+
+    private static boolean testTreeMethods() {
+        try {
+            final PhylogenyFactory factory = ParserBasedPhylogenyFactory.getInstance();
+            final Phylogeny t0 = factory.create( "((((A,B)ab,C)abc,D)abcd,E)", new NHXParser() )[ 0 ];
+            PhylogenyMethods.collapseSubtreeStructure( t0.getNode( "abcd" ) );
+            if ( !t0.toNewHampshireX().equals( "((A,B,C,D)abcd,E)" ) ) {
+                System.out.println( t0.toNewHampshireX() );
                 return false;
             }
-            if ( !ForesterUtil.isEmpty( entry3.getGeneName() ) ) {
+            final Phylogeny t1 = factory.create( "((((A:0.1,B)ab:0.2,C)abc:0.3,D)abcd:0.4,E)", new NHXParser() )[ 0 ];
+            PhylogenyMethods.collapseSubtreeStructure( t1.getNode( "abcd" ) );
+            if ( !isEqual( t1.getNode( "A" ).getDistanceToParent(), 0.6 ) ) {
                 return false;
             }
-            if ( entry3.getCrossReferences().size() != 8 ) {
+            if ( !isEqual( t1.getNode( "B" ).getDistanceToParent(), 0.5 ) ) {
                 return false;
             }
-            //
-            //
-            final SequenceDatabaseEntry entry4 = SequenceDbWsTools.obtainEntry( "AAA36557.1" );
-            if ( !entry4.getAccession().equals( "AAA36557" ) ) {
+            if ( !isEqual( t1.getNode( "C" ).getDistanceToParent(), 0.3 ) ) {
                 return false;
             }
-            //
-            //TODO fails:
-            //            final SequenceDatabaseEntry entry5 = SequenceDbWsTools.obtainEntry( "M30539" );
-            //            if ( !entry5.getAccession().equals( "HM043801" ) ) {
-            //                return false;
-            //            }
-        }
-        catch ( final IOException e ) {
-            System.out.println();
-            System.out.println( "the following might be due to absence internet connection:" );
-            e.printStackTrace( System.out );
-            return true;
         }
         catch ( final Exception e ) {
-            e.printStackTrace();
+            e.printStackTrace( System.out );
             return false;
         }
         return true;
@@ -11192,7 +12797,7 @@ public final class Test {
 
     private static boolean testUniprotEntryRetrieval() {
         try {
-            final SequenceDatabaseEntry entry = SequenceDbWsTools.obtainUniProtEntry( "P12345", 200 );
+            final SequenceDatabaseEntry entry = SequenceDbWsTools.obtainUniProtEntry( "P12345", 5000 );
             if ( !entry.getAccession().equals( "P12345" ) ) {
                 return false;
             }
@@ -11211,6 +12816,18 @@ public final class Test {
             if ( !entry.getTaxonomyIdentifier().equals( "9986" ) ) {
                 return false;
             }
+            if ( entry.getMolecularSequence() == null ) {
+                return false;
+            }
+            if ( !entry
+                    .getMolecularSequence()
+                    .getMolecularSequenceAsString()
+                    .startsWith( "MALLHSARVLSGVASAFHPGLAAAASARASSWWAHVEMGPPDPILGVTEAYKRDTNSKKMNLGVGAYRDDNGKPYVLPSVRKAEAQIAAKGLDKEYLPIGGLAEFCRASAELALGENSEV" )
+                    || !entry.getMolecularSequence().getMolecularSequenceAsString().endsWith( "LAHAIHQVTK" ) ) {
+                System.out.println( "got: " + entry.getMolecularSequence().getMolecularSequenceAsString() );
+                System.out.println( "expected something else." );
+                return false;
+            }
         }
         catch ( final IOException e ) {
             System.out.println();
@@ -11218,6 +12835,10 @@ public final class Test {
             e.printStackTrace( System.out );
             return true;
         }
+        catch ( final NullPointerException f ) {
+            f.printStackTrace( System.out );
+            return false;
+        }
         catch ( final Exception e ) {
             return false;
         }
@@ -11407,60 +13028,6 @@ public final class Test {
         }
         return true;
     }
-
-    private static boolean testWabiTxSearch() {
-        try {
-            String result = "";
-            result = TxSearch.searchSimple( "nematostella" );
-            result = TxSearch.getTxId( "nematostella" );
-            if ( !result.equals( "45350" ) ) {
-                return false;
-            }
-            result = TxSearch.getTxName( "45350" );
-            if ( !result.equals( "Nematostella" ) ) {
-                return false;
-            }
-            result = TxSearch.getTxId( "nematostella vectensis" );
-            if ( !result.equals( "45351" ) ) {
-                return false;
-            }
-            result = TxSearch.getTxName( "45351" );
-            if ( !result.equals( "Nematostella vectensis" ) ) {
-                return false;
-            }
-            result = TxSearch.getTxId( "Bacillus subtilis subsp. subtilis str. N170" );
-            if ( !result.equals( "536089" ) ) {
-                return false;
-            }
-            result = TxSearch.getTxName( "536089" );
-            if ( !result.equals( "Bacillus subtilis subsp. subtilis str. N170" ) ) {
-                return false;
-            }
-            final List<String> queries = new ArrayList<String>();
-            queries.add( "Campylobacter coli" );
-            queries.add( "Escherichia coli" );
-            queries.add( "Arabidopsis" );
-            queries.add( "Trichoplax" );
-            queries.add( "Samanea saman" );
-            queries.add( "Kluyveromyces marxianus" );
-            queries.add( "Bacillus subtilis subsp. subtilis str. N170" );
-            queries.add( "Bornavirus parrot/PDD/2008" );
-            final List<RANKS> ranks = new ArrayList<RANKS>();
-            ranks.add( RANKS.SUPERKINGDOM );
-            ranks.add( RANKS.KINGDOM );
-            ranks.add( RANKS.FAMILY );
-            ranks.add( RANKS.GENUS );
-            ranks.add( RANKS.TRIBE );
-            result = TxSearch.searchLineage( queries, ranks );
-            result = TxSearch.searchParam( "Homo sapiens", TAX_NAME_CLASS.ALL, TAX_RANK.SPECIES, 10, true );
-            result = TxSearch.searchParam( "Samanea saman", TAX_NAME_CLASS.SCIENTIFIC_NAME, TAX_RANK.ALL, 10, true );
-        }
-        catch ( final Exception e ) {
-            System.out.println();
-            System.out.println( "the following might be due to absence internet connection:" );
-            e.printStackTrace( System.out );
-            return false;
-        }
-        return true;
-    }
+    
+    
 }