+#-------------------------------------------------------------------------------
+# Jalview - A Sequence Alignment Editor and Viewer (Version 2.5.1)
+# Copyright (C) 2010 J Procter, AM Waterhouse, G Barton, M Clamp, S Searle
+#
+# This file is part of Jalview.
+#
+# Jalview is free software: you can redistribute it and/or
+# modify it under the terms of the GNU General Public License
+# as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version.
+#
+# Jalview is distributed in the hope that it will be useful, but
+# WITHOUT ANY WARRANTY; without even the implied warranty
+# of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+# PURPOSE. See the GNU General Public License for more details.
+#
+# You should have received a copy of the GNU General Public License along with Jalview. If not, see <http://www.gnu.org/licenses/>.
+#-------------------------------------------------------------------------------
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* Jalview - A Sequence Alignment Editor and Viewer (Version 2.5)
*
* You should have received a copy of the GNU General Public License along with Jalview. If not, see <http://www.gnu.org/licenses/>.
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+<head><title>Alignment Conservation Annotation</title></head>
+<body><p><strong>Alignment Conservation Annotation</strong></p>
+<p>This is an automatically calculated quantitative alignment
+annotation which measures the number of conserved physico-chemical
+properties conserved for each column of the alignment. Its calculation
+is based on the one used in
+ the AMAS method of multiple sequence alignment analysis :<br>
+<ul>Livingstone
+ C.D. and Barton G.J. (1993), Protein Sequence Alignments: A Strategy
+ for the Hierarchical Analysis of Residue Conservation.<em>CABIOS</em> Vol. <b>9</b>
+ No. 6 (745-756)).
+</ul>
+</p>
+<p>Conservation is measured as a numerical index reflecting the conservation of
+ <a href="../misc/aaproperties.html">physico-chemical
+ properties</a> in the alignment: Identities score highest, and the next most
+ conserved group contain substitutions to amino acids lying in the same physico-chemical
+ class.</p>
+
+<p><em>Colouring an alignment by conservation</em><br>
+Conservation scores can be used to colour an alignment. This is
+explained further in the help page for <a
+href="../colourSchemes/conservation.html">conservation colouring</a>.
+</p>
+</body>
+</html>
git://source.jalview.org / jalview.git / blobdiff