<html>
<!--
- * Jalview - A Sequence Alignment Editor and Viewer (Version 2.5)
- * Copyright (C) 2010 J Procter, AM Waterhouse, G Barton, M Clamp, S Searle
+ * Jalview - A Sequence Alignment Editor and Viewer (Version 2.7)
+ * Copyright (C) 2011 J Procter, AM Waterhouse, G Barton, M Clamp, S Searle
*
* This file is part of Jalview.
*
*
* You should have received a copy of the GNU General Public License along with Jalview. If not, see <http://www.gnu.org/licenses/>.
-->
+<head><title>Pairwise Alignment</title></head>
+<body>
+<p><strong>Pairwise alignment (Proteins only)</strong></p>
+<p>This calculation is performed on the selected sequences only. Java is not the
+ fastest language in the world and aligning more than a handful of sequences
+ will take a fair amount of time. <br>
+ For each pair of sequences the best global alignment is found using BLOSUM62
+ as the scoring matrix. The scores reported are the raw scores. The sequences
+ are aligned using a dynamic programming technique and using the following gap
+ penalties : </p>
+<p>Gap open : 12 <br>
+ Gap extend : 2 </p>
+<p>When you select the pairwise alignment option a new window will come up which
+ will display the alignments in a text format as they are calculated. Also displayed
+ is information about the alignment such as alignment score, length and percentage
+ identity between the sequences.</p>
+<p> </p>
+</body>
+</html>