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-<head><title>What's new ?</title></head>
+<!--
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
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+ * This file is part of Jalview.
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+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ -->
+<head>
+<title>What's new ?</title>
+</head>
<body>
-<p><strong>What's new ?</strong> </p>
-<p>If you are reading this then you will already have seen some of the recent changes
- made to Jalview.<br>
- Jalview takes advantage of some of the more recent user interface developments
- in the Java programming language. For instance Jalview is now a multi windowed
- application, this keeps all your Jalview windows neatly together in one main
- application window. </p>
-<p>If you were familiar with the original Jalview, here is a list of important
- features you should know about the current development:</p>
-<ul>
- <li>Editing sequences is no longer the default when mouse clicking the alignment.
- Instead, mouse clicking on the alignment creates a "selection region"
- which may be full sequences or groups of residues.</li>
- <li>To insert or edit the gaps in one sequence in alignment, the
- "Shift" key must be held down when dragging the mouse.</li>
- <li>To insert or edit gaps for a group of sequences, the
- "Alt" key (or in X windows the "Control"
- key) must be held down.</li>
- <li>Selecting colour schemes in the colour menu either sets just the
- "background" colourscheme for the alignment, or - when
- the tickbox "Apply colour to all groups" is ticked,
- applies the scheme to the background and all groups defined on the alignment.</li>
- <li>Use the right mouse button (apple and click on the Mac) whilst
- the pointer is within the selection area to access the "define" region menu to
- define a new region, give it a name, and change its colourscheme and display
- properties.</li>
- <li>Conservation is automatically updated whenever the alignment is edited</li>
- <li>There is no "quick draw" option</li>
- <li>Edits can be undone, and redone!</li>
-</ul>
+ <p>
+ <strong>What's new ?</strong>
+ </p>
+ <p>
+ Jalview 2.10 is the next major release in the Jalview 2 series. Full
+ details are in the <a href="releases.html#Jalview.2.10.0">Jalview
+ 2.10 Release Notes</a>, but the highlights are below.
+ </p>
+ <p>
+ <strong>Highlights in Jalview 2.10</strong>
+ <ul>
+ <li><strong>Ensembl sequence fetcher.</strong> Annotated Genes,
+ transcripts and proteins can be retrieved via Jalview's new <a
+ href="features/ensemblsequencefetcher.html">Ensembl REST
+ client</a>. Support for import of Ensembl data also allows:
+ <ul>
+ <li><strong>Sequence variant data.</strong> Jalview
+ propagates variant annotation imported via Ensembl onto
+ protein products, complete with associated metadata such as
+ clinical significance.</li>
+ <li><strong>Aligned locus view.</strong> Transcripts
+ retrieved for a gene identifier via the Ensembl or
+ EnsemblGenomes sequence databases are automatically aligned to
+ their reference genome.</li>
+ </ul></li>
+ <li><strong>Working with structures.</strong>
+ <ul>
+ <li><strong>More accurate structure mappings.</strong>
+ Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI)
+ to match structures to UniProt sequences, even for structures
+ containing multiple copies of a sequence.</li>
+ <li><strong>Import structures as mmCIF</strong>. Jalview
+ now downloads data from the EMBL-EBI's PDBe site as mmCIF.
+ mmCIF files allow Jalview to handle very large structures,
+ such as the HIV virus capsid assembly.</li>
+ </ul></li>
+ <li><strong>UniProt Free Text Search</strong>. The new search
+ dialog for UniProt allows you to browse and retrieve sequences
+ from UniProt with free-text search and more structured queries</li>
+ <li><strong>Reference sequence based alignment
+ visualisation.</strong>. When a reference sequence is defined for the
+ alignment, the alignment column ruler is now numbered according to
+ the reference sequence. The reference sequence for alignment views
+ can also be saved and restored from Jalview projects.</li>
+ <li></li>
+ </ul>
+
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