<html>
+<!--
+ * Jalview - A Sequence Alignment Editor and Viewer ($$Version-Rel$$)
+ * Copyright (C) $$Year-Rel$$ The Jalview Authors
+ *
+ * This file is part of Jalview.
+ *
+ * Jalview is free software: you can redistribute it and/or
+ * modify it under the terms of the GNU General Public License
+ * as published by the Free Software Foundation, either version 3
+ * of the License, or (at your option) any later version.
+ *
+ * Jalview is distributed in the hope that it will be useful, but
+ * WITHOUT ANY WARRANTY; without even the implied warranty
+ * of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+ * PURPOSE. See the GNU General Public License for more details.
+ *
+ * You should have received a copy of the GNU General Public License
+ * along with Jalview. If not, see <http://www.gnu.org/licenses/>.
+ * The Jalview Authors are detailed in the 'AUTHORS' file.
+ -->
<head>
<title>What's new ?</title>
</head>
<body>
-<p><strong>What's new ?</strong></p>
-<p><strong>Jalview Version 2.4</strong></p>
-<ul>
- VAMSAS Interoperation Client<br>
- DAS Sequence Fetching<br>
- PFAM full alignment retrieval<br>
- DNA/Protein Product traversal (Experimental)</br>
- .. (more to come)<br>
- URL links can be generated using regular
- expressions and created for sequence database cross references<br>
-</ul>
-<p><strong>Issues Resolved</strong></p>
-<ul>
- .. (more to come)
-</ul>
+ <p>
+ <strong>What's new ?</strong>
+ </p>
+ <p>
+ Jalview 2.10 is the next major release in the Jalview 2 series. Full
+ details are in the <a href="releases.html#Jalview.2.10.0">Jalview
+ 2.10 Release Notes</a>, but the highlights are below.
+ </p>
+ <p>
+ <strong>Highlights in Jalview 2.10</strong>
+ <ul>
+ <li><strong>Ensembl sequence fetcher.</strong> Annotated Genes,
+ transcripts and proteins can be retrieved via Jalview's new <a
+ href="features/ensemblsequencefetcher.html">Ensembl REST
+ client</a>. Support for import of Ensembl data also allows:
+ <ul>
+ <li><strong>Sequence variant data.</strong> Jalview
+ propagates variant annotation imported via Ensembl onto
+ protein products, complete with associated metadata such as
+ clinical significance.</li>
+ <li><strong>Aligned locus view.</strong> Transcripts
+ retrieved for a gene identifier via the Ensembl or
+ EnsemblGenomes sequence databases are automatically aligned to
+ their reference genome.</li>
+ </ul></li>
+ <li><strong>Working with structures.</strong>
+ <ul>
+ <li><strong>More accurate structure mappings.</strong>
+ Jalview now utilises the PDBe's SIFTS database (at EMBL-EBI)
+ to match structures to UniProt sequences, even for structures
+ containing multiple copies of a sequence.</li>
+ <li><strong>Import structures as mmCIF</strong>. Jalview
+ now downloads data from the EMBL-EBI's PDBe site as mmCIF.
+ mmCIF files allow Jalview to handle very large structures,
+ such as the HIV virus capsid assembly.</li>
+ </ul></li>
+ <li><strong>UniProt Free Text Search</strong>. The new search
+ dialog for UniProt allows you to browse and retrieve sequences
+ from UniProt with free-text search and more structured queries</li>
+ <li><strong>Reference sequence based alignment
+ visualisation.</strong>. When a reference sequence is defined for the
+ alignment, the alignment column ruler is now numbered according to
+ the reference sequence. The reference sequence for alignment views
+ can also be saved and restored from Jalview projects.</li>
+ <li></li>
+ </ul>
-<--<p><strong>Jalview Version 2.3</strong></p>
-<ul>
- Jmol 11.0.2 integration<br>
- PDB views stored in Jalview XML files<br>
- Slide sequences<br>
- Edit sequence in place<br>
- EMBL CDS features<br>
- DAS Feature mapping<br>
- Feature ordering<br>
- Alignment Properties<br>
- Annotation Scores<br>
- Sort by scores<br>
- Feature/annotation editing in applet<br>
-</ul>
-<p><strong>Issues Resolved</strong></p>
-<ul>
- Headless state operation in 2.2.1 <br>
- Incorrect and unstable DNA pairwise alignment <br>
- Cut and paste of sequences with annotation <br>
- Feature group display state in XML<br>
- Feature ordering in XML<br>
- 2.2.1 applet had no feature transparency<br>
- Number pad keys can be used in cursor mode<br>
- Structure Viewer mirror image resolved</p>
- </ul>-->
-<p> </p>
-<p>See the <a href="releases.html">Release History</a> page for
-details of all new features and resolved issues.</p>
</body>
</html>