import static org.testng.AssertJUnit.assertTrue;
import jalview.api.AlignViewportI;
+import jalview.commands.EditCommand;
+import jalview.commands.EditCommand.Action;
+import jalview.commands.EditCommand.Edit;
import jalview.datamodel.AlignedCodonFrame;
+import jalview.datamodel.Alignment;
import jalview.datamodel.AlignmentI;
import jalview.datamodel.ColumnSelection;
import jalview.datamodel.SearchResults;
import java.util.Arrays;
import java.util.Collections;
import java.util.HashSet;
+import java.util.LinkedHashSet;
import java.util.List;
import java.util.Set;
@Test(groups = { "Functional" })
public void testBuildSearchResults()
{
- final Sequence seq1 = new Sequence("Seq1", "C-G-TA-GC");
+ final Sequence seq1 = new Sequence("Seq1/5-10", "C-G-TA-GC");
seq1.createDatasetSequence();
- final Sequence aseq1 = new Sequence("Seq1", "-P-R");
+ final Sequence aseq1 = new Sequence("Seq1/12-13", "-P-R");
aseq1.createDatasetSequence();
/*
- * Map dna bases 1-6 to protein residues 1-2
+ * Map dna bases 5-10 to protein residues 12-13
*/
AlignedCodonFrame acf = new AlignedCodonFrame();
- MapList map = new MapList(new int[] { 1, 6 }, new int[] { 1, 2 }, 3, 1);
+ MapList map = new MapList(new int[] { 5, 10 }, new int[] { 12, 13 }, 3,
+ 1);
acf.addMap(seq1.getDatasetSequence(), aseq1.getDatasetSequence(), map);
Set<AlignedCodonFrame> acfList = Collections.singleton(acf);
/*
- * Check protein residue 1 maps to codon 1-3, 2 to codon 4-6
+ * Check protein residue 12 maps to codon 5-7, 13 to codon 8-10
*/
- SearchResults sr = MappingUtils.buildSearchResults(aseq1, 1, acfList);
+ SearchResults sr = MappingUtils.buildSearchResults(aseq1, 12, acfList);
assertEquals(1, sr.getResults().size());
Match m = sr.getResults().get(0);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(1, m.getStart());
- assertEquals(3, m.getEnd());
- sr = MappingUtils.buildSearchResults(aseq1, 2, acfList);
+ assertEquals(5, m.getStart());
+ assertEquals(7, m.getEnd());
+ sr = MappingUtils.buildSearchResults(aseq1, 13, acfList);
assertEquals(1, sr.getResults().size());
m = sr.getResults().get(0);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(4, m.getStart());
- assertEquals(6, m.getEnd());
+ assertEquals(8, m.getStart());
+ assertEquals(10, m.getEnd());
/*
- * Check inverse mappings, from codons 1-3, 4-6 to protein 1, 2
+ * Check inverse mappings, from codons 5-7, 8-10 to protein 12, 13
*/
- for (int i = 1; i < 7; i++)
+ for (int i = 5; i < 11; i++)
{
sr = MappingUtils.buildSearchResults(seq1, i, acfList);
assertEquals(1, sr.getResults().size());
m = sr.getResults().get(0);
assertEquals(aseq1.getDatasetSequence(), m.getSequence());
- int residue = i > 3 ? 2 : 1;
+ int residue = i > 7 ? 13 : 12;
assertEquals(residue, m.getStart());
assertEquals(residue, m.getEnd());
}
@Test(groups = { "Functional" })
public void testBuildSearchResults_withIntron()
{
- final Sequence seq1 = new Sequence("Seq1", "C-G-TAGA-GCAGCTT");
+ final Sequence seq1 = new Sequence("Seq1/5-17", "c-G-tAGa-GcAgCtt");
seq1.createDatasetSequence();
- final Sequence aseq1 = new Sequence("Seq1", "-P-R");
+ final Sequence aseq1 = new Sequence("Seq1/8-9", "-E-D");
aseq1.createDatasetSequence();
/*
- * Map dna bases [2, 4, 5], [7, 9, 11] to protein residues 1 and 2
+ * Map dna bases [6, 8, 9], [11, 13, 115] to protein residues 8 and 9
*/
AlignedCodonFrame acf = new AlignedCodonFrame();
- MapList map = new MapList(new int[] { 2, 2, 4, 5, 7, 7, 9, 9, 11, 11 },
- new int[] { 1, 2 }, 3, 1);
+ MapList map = new MapList(new int[] { 6, 6, 8, 9, 11, 11, 13, 13, 15,
+ 15 }, new int[] { 8, 9 }, 3, 1);
acf.addMap(seq1.getDatasetSequence(), aseq1.getDatasetSequence(), map);
Set<AlignedCodonFrame> acfList = Collections.singleton(acf);
/*
- * Check protein residue 1 maps to [2, 4, 5]
+ * Check protein residue 8 maps to [6, 8, 9]
*/
- SearchResults sr = MappingUtils.buildSearchResults(aseq1, 1, acfList);
+ SearchResults sr = MappingUtils.buildSearchResults(aseq1, 8, acfList);
assertEquals(2, sr.getResults().size());
Match m = sr.getResults().get(0);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(2, m.getStart());
- assertEquals(2, m.getEnd());
+ assertEquals(6, m.getStart());
+ assertEquals(6, m.getEnd());
m = sr.getResults().get(1);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(4, m.getStart());
- assertEquals(5, m.getEnd());
+ assertEquals(8, m.getStart());
+ assertEquals(9, m.getEnd());
/*
- * Check protein residue 2 maps to [7, 9, 11]
+ * Check protein residue 9 maps to [11, 13, 15]
*/
- sr = MappingUtils.buildSearchResults(aseq1, 2, acfList);
+ sr = MappingUtils.buildSearchResults(aseq1, 9, acfList);
assertEquals(3, sr.getResults().size());
m = sr.getResults().get(0);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(7, m.getStart());
- assertEquals(7, m.getEnd());
+ assertEquals(11, m.getStart());
+ assertEquals(11, m.getEnd());
m = sr.getResults().get(1);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(9, m.getStart());
- assertEquals(9, m.getEnd());
+ assertEquals(13, m.getStart());
+ assertEquals(13, m.getEnd());
m = sr.getResults().get(2);
assertEquals(seq1.getDatasetSequence(), m.getSequence());
- assertEquals(11, m.getStart());
- assertEquals(11, m.getEnd());
+ assertEquals(15, m.getStart());
+ assertEquals(15, m.getEnd());
/*
* Check inverse mappings, from codons to protein
*/
- for (int i = 1; i < 14; i++)
+ for (int i = 5; i < 18; i++)
{
sr = MappingUtils.buildSearchResults(seq1, i, acfList);
- int residue = (i == 2 || i == 4 || i == 5) ? 1 : (i == 7 || i == 9
- || i == 11 ? 2 : 0);
+ int residue = (i == 6 || i == 8 || i == 9) ? 8 : (i == 11 || i == 13
+ || i == 15 ? 9 : 0);
if (residue == 0)
{
assertEquals(0, sr.getResults().size());
}
/**
+ * Set up mappings for tests from 3 dna to 3 protein sequences. Sequences have
+ * offset start positions for a more general test case.
+ *
* @throws IOException
*/
protected void setupMappedAlignments() throws IOException
* Set up dna and protein Seq1/2/3 with mappings (held on the protein
* viewport). Lower case for introns.
*/
- AlignmentI cdna = loadAlignment(">Seq1\nAC-GctGtC-T\n"
- + ">Seq2\nTc-GA-G-T-Tc\n" + ">Seq3\nTtTT-AaCGg-\n", "FASTA");
+ AlignmentI cdna = loadAlignment(">Seq1/10-18\nAC-GctGtC-T\n"
+ + ">Seq2/20-27\nTc-GA-G-T-Tc\n" + ">Seq3/30-38\nTtTT-AaCGg-\n",
+ "FASTA");
cdna.setDataset(null);
AlignmentI protein = loadAlignment(
- ">Seq1\n-K-P\n>Seq2\nL--Q\n>Seq3\nG--S\n", "FASTA");
+ ">Seq1/40-41\n-K-P\n>Seq2/50-51\nL--Q\n>Seq3/60-61\nG--S\n",
+ "FASTA");
protein.setDataset(null);
+
+ // map first dna to first protein seq
AlignedCodonFrame acf = new AlignedCodonFrame();
- MapList map = new MapList(new int[] { 1, 3, 6, 6, 8, 9 }, new int[] {
- 1, 2 }, 3, 1);
+ MapList map = new MapList(new int[] { 10, 12, 15, 15, 17, 18 },
+ new int[] { 40, 41 }, 3, 1);
acf.addMap(cdna.getSequenceAt(0).getDatasetSequence(), protein
.getSequenceAt(0).getDatasetSequence(), map);
- map = new MapList(new int[] { 1, 1, 3, 4, 5, 7 }, new int[] { 1, 2 },
+
+ // map second dna to second protein seq
+ map = new MapList(new int[] { 20, 20, 22, 23, 24, 26 }, new int[] { 50,
+ 51 },
3, 1);
acf.addMap(cdna.getSequenceAt(1).getDatasetSequence(), protein
.getSequenceAt(1).getDatasetSequence(), map);
- map = new MapList(new int[] { 1, 1, 3, 4, 5, 5, 7, 8 }, new int[] { 1,
- 2 }, 3, 1);
+
+ // map third dna to third protein seq
+ map = new MapList(new int[] { 30, 30, 32, 34, 36, 37 }, new int[] { 60,
+ 61 }, 3, 1);
acf.addMap(cdna.getSequenceAt(2).getDatasetSequence(), protein
.getSequenceAt(2).getDatasetSequence(), map);
Set<AlignedCodonFrame> acfList = Collections.singleton(acf);
result = MappingUtils.findMappingsForSequence(null, null);
assertEquals(0, result.size());
}
+
+ @Test(groups = { "Functional" })
+ public void testMapEditCommand()
+ {
+ SequenceI dna = new Sequence("Seq1", "---ACG---GCATCA", 8, 16);
+ SequenceI protein = new Sequence("Seq2", "-T-AS", 5, 7);
+ dna.createDatasetSequence();
+ protein.createDatasetSequence();
+ AlignedCodonFrame acf = new AlignedCodonFrame();
+ MapList map = new MapList(new int[] { 8, 16 }, new int[] { 5, 7 }, 3, 1);
+ acf.addMap(dna.getDatasetSequence(), protein.getDatasetSequence(), map);
+ Set<AlignedCodonFrame> mappings = new LinkedHashSet<AlignedCodonFrame>();
+ mappings.add(acf);
+
+ AlignmentI prot = new Alignment(new SequenceI[] { protein });
+ prot.setCodonFrames(mappings);
+ AlignmentI nuc = new Alignment(new SequenceI[] { dna });
+
+ /*
+ * construct and perform the edit command to turn "-T-AS" in to "-T-A--S"
+ * i.e. insert two gaps at column 4
+ */
+ EditCommand ec = new EditCommand();
+ final Edit edit = ec.new Edit(Action.INSERT_GAP,
+ new SequenceI[] { protein }, 4, 2, '-');
+ ec.appendEdit(edit, prot, true, null);
+
+ /*
+ * the mapped edit command should be to insert 6 gaps before base 4 in the
+ * nucleotide sequence, which corresponds to aligned column 12 in the dna
+ */
+ EditCommand mappedEdit = MappingUtils.mapEditCommand(ec, false, nuc,
+ '-', mappings);
+ assertEquals(1, mappedEdit.getEdits().size());
+ Edit e = mappedEdit.getEdits().get(0);
+ assertEquals(1, e.getSequences().length);
+ assertEquals(dna, e.getSequences()[0]);
+ assertEquals(12, e.getPosition());
+ assertEquals(6, e.getNumber());
+ }
}
git://source.jalview.org / jalview.git / commitdiff