1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 M-------------------NGTE--GDNFYVPFSNKTGLA--RSPYEYPQY-YL-----
3 ------------------------------------------------------------
4 --AEPWKYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLF
5 G-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN
6 F-RFGNTHAIMGVAFTWIMALAC-AAPPLV-GWS-----RYIPEGMQCSCGPDYYTLNPN
7 FNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAAQQ-------------------
8 ------------------------------------------------------------
9 ------------------------------------------------------------
10 --ESASTQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT--HQGSD-FGATFMTLPAF
11 FAKSSALYNPVIYILMNKQFRNCMITTL-----CCGKNPLGDDE--SGASTSKTEVSSVS
12 T-----------------------------------------------------------
13 -----------------------------------SPVSPA
14 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
15 M-------------------NGTE--GPNFYVPFSNITGVV--RSPFEQPQY-YL-----
16 ------------------------------------------------------------
17 --AEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFG
18 G-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN
19 F-RFGENHAIMGVAFTWVMALAC-AAPPLV-GWS-----RYIPEGMQCSCGIDYYTLKPE
20 VNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQ-------------------
21 ------------------------------------------------------------
22 ------------------------------------------------------------
23 --ESATTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFT--HQGSN-FGPIFMTLPAF
24 FAKTASIYNPIIYIMMNKQFRNCMLTSL-----CCGKNPLGDDE--ASATASKTET----
25 ------------------------------------------------------------
26 -----------------------------------SQVAPA
27 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
28 M-------------------NGTE--GINFYVPMSNKTGVV--RSPFEYPQY-YL-----
29 ------------------------------------------------------------
30 --AEPWKYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACF
31 G-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN
32 F-RFSATHAMMGIAFTWVMAFSC-AAPPLF-GWS-----RYMPEGMQCSCGPDYYTHNPD
33 YHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQQQ-------------------
34 ------------------------------------------------------------
35 ------------------------------------------------------------
36 --ESATTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT--NKGAD-FTATLMAVPAF
37 FSKSSSLYNPIIYVLMNKQFRNCMITTI-----CCGKNPFGDEDVSSTVSQSKTEVSSVS
38 S-----------------------------------------------------------
39 -----------------------------------SQVSPA
40 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
41 M-------------------NGTE--GKNFYVPMSNRTGLV--RSPFEYPQY-YL-----
42 ------------------------------------------------------------
43 --AEPWQFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCF
44 G-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS
45 F-KFSSSHAFAGIAFTWVMALAC-AAPPLF-GWS-----RYIPEGMQCSCGPDYYTLNPD
46 YNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQQQ-------------------
47 ------------------------------------------------------------
48 ------------------------------------------------------------
49 --DSASTQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFF--NKGAD-FSAKFMAIPAF
50 FSKSSALYNPVIYVLLNKQFRNCMLTTI-----FCGKNPLGDDE-SSTVSTSKTEVSS--
51 ------------------------------------------------------------
52 -------------------------------------VSPA
53 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
54 M-------------------NGTE--GNNFYVPLSNRTGLV--RSPFEYPQY-YL-----
55 ------------------------------------------------------------
56 --AEPWQFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCF
57 G-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS
58 F-KFSSTHASAGIAFTWVMAMAC-AAPPLV-GWS-----RYIPEGIQCSCGPDYYTLNPE
59 YNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQQQ-------------------
60 ------------------------------------------------------------
61 ------------------------------------------------------------
62 --DSASTQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFF--NKGAA-FSAQFMAIPAF
63 FSKTSALYNPVIYVLLNKQFRSCMLTTL-----FCGKNPLGDEE-SSTVSTSKTEVSS--
64 ------------------------------------------------------------
65 -------------------------------------VSPA
66 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
67 M-------------------KQVPEFHEDFYIPIPLDINNLSAYSPFLVPQD-HL-----
68 ------------------------------------------------------------
69 --GNQGIFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIF
70 G-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN
71 F-TFKTPHAIAGCILPWISALAA-SLPPLF-GWS-----RYIPEGLQCSCGPDWYTTNNK
72 YNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQA-------------------
73 ------------------------------------------------------------
74 ------------------------------------------------------------
75 --DSASTQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVS--HRGEE-FDLRMATIPSC
76 LSKASTVYNPVIYVLMNKQFRSCMMKMV------CGKNIEEDEA---STSSQVTQVSSVA
77 P-----------------------------------------------------------
78 ---------------------------------------EK
79 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
80 M-------------------RKMS--EEEFYLFKNISS-----VGPWDGPQY-HI-----
81 ------------------------------------------------------------
82 --APVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIF
83 S-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN
84 F-RFSSKHALTVVLATWTIGIGV-SIPPFF-GWS-----RFIPEGLQCSCGPDWYTVGTK
85 YRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQ-------------------
86 ------------------------------------------------------------
87 ------------------------------------------------------------
88 --ESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN--NRNHG-LDLRLVTIPSF
89 FSKSACIYNPIIYCFMNKQFQACIMKMV------CGKAMTDESD---TCSSQKTEVSTVS
90 S-----------------------------------------------------------
91 -----------------------------------TQVGPN
92 > 8=opsin, greensensitive human (fragment) S07060
93 ------------------------------------------------------------
94 ------------------------------------------------------------
95 -----------------------------------------------------DLAETVI
96 A-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN
97 V-RFDAKLAIVGIAFSWIWAAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSY
98 PGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQK-------------------
99 ------------------------------------------------------------
100 ------------------------------------------------------------
101 --ESESTQKAEKEVTRMVVVMVLAFC----------------------------------
102 ------------------------------------------------------------
103 ------------------------------------------------------------
104 -----------------------------------------
105 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
106 MAQQWSLQRLAGRHPQDSYEDSTQ--SSIFTYTNSNST-----RGPFEGPNY-HI-----
107 ------------------------------------------------------------
108 --APRWVYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI
109 A-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN
110 V-RFDAKLAIVGIAFSWIWAAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSY
111 PGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQK-------------------
112 ------------------------------------------------------------
113 ------------------------------------------------------------
114 --ESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA--NPGYP-FHPLMAALPAF
115 FAKSATIYNPVIYVFMNRQFRNCILQLF-------GKKVDDGSE-LS--SASKTEVSSV-
116 ------------------------------------------------------------
117 -----------------------------------SSVSPA
118 > 10== Z68193 1 human Red Opsin <>[]
119 MAQQWSLQRLAGRHPQDSYEDSTQ--SSIFTYTNSNST-----RGPFEGPNY-HI-----
120 ------------------------------------------------------------
121 --APRWVYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVI
122 A-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN
123 V-RFDAKLAIVGIAFSWIWSAVW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSY
124 PGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQK-------------------
125 ------------------------------------------------------------
126 ------------------------------------------------------------
127 --ESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA--NPGYA-FHPLMAALPAY
128 FAKSATIYNPVIYVFMNRQFRNCILQLF-------GKKVDDGSE-LS--SASKTEVSSV-
129 ------------------------------------------------------------
130 -----------------------------------SSVSPA
131 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
132 MTEAWNVAVFAARRSRDD-DDTTR--GSVFTYTNTNNT-----RGPFEGPNY-HI-----
133 ------------------------------------------------------------
134 --APRWVYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLV
135 A-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN
136 I-KFDSKLAIIGIVFSWVWAWGW-SAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSVE
137 LGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQK-------------------
138 ------------------------------------------------------------
139 ------------------------------------------------------------
140 --ESESTQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAA--NPGYA-FHPLAAALPAY
141 FAKSATIYNPVIYVFMNRQFRNCIMQLF-------GKKVDDGSE-AS--TTSRTEVSSVS
142 N-----------------------------------------------------------
143 -----------------------------------SSVAPA
144 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
145 MA-AWE-AAFAARRRHEE-EDTTR--DSVFTYTNSNNT-----RGPFEGPNY-HI-----
146 ------------------------------------------------------------
147 --APRWVYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVI
148 A-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN
149 I-KFDGKLAVAGILFSWLWSCAW-TAPPIF-GWS-----RYWPHGLKTSCGPDVFSGSSD
150 PGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQQK-------------------
151 ------------------------------------------------------------
152 ------------------------------------------------------------
153 --ESESTQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA--NPGYA-FHPLAAALPAY
154 FAKSATIYNPIIYVFMNRQFRNCILQLF-------GKKVDDGSE-VS---TSRTEVSSVS
155 N-----------------------------------------------------------
156 -----------------------------------SSVSPA
157 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
158 M-------------------------SSNSSQAPPNGT-----PGPFDGPQWPYQ-----
159 ------------------------------------------------------------
160 --APQSTYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLC
161 G-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD
162 F-QFQRRHAVSGCAFTWGWALLW-SAPPLL-GWS-----SYVPEGLRTSCGPNWYTGGS-
163 -NNNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQQK-------------------
164 ------------------------------------------------------------
165 ------------------------------------------------------------
166 --EADTTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVAT--HKGII-IQPVLASLPSY
167 FSKTATVYNPIIYVFMNKQFQSCLLEML-----CCGYQPQRTGKASPGTPGPHADVTAAG
168 L-----------------------------------------------------------
169 -------------------------------RNKVMPAHPV
170 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
171 MESGNVSSSLFGNVSTALRPEARLSAE----------TRLLGWNVPPEELR---H-----
172 ---------------------------------------IPEHWLTYPE-----------
173 --PPESMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK
174 --TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG
175 --KMTHGKAIAMIIFIYMYATPW-VVACYTETWG-----RFVPEGYLTSCTFDYLTDNF-
176 -DTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVESLR-------
177 ------------------------------------------------------------
178 ------------------------------------------------------------
179 SNVDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAF--GDKTL-LTPGATMIPAC
180 ACKMVACIDPFVYAISHPRYRMELQKRCPWL--ALNEKAPE-------SSAVASTSTTQE
181 P-----------------------------------------------------------
182 -----------------------------------QQTTAA
183 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
184 MEYHNVSSVL-GNVSSVLRPDARLSAE----------SRLLGWNVPPDELR---H-----
185 ---------------------------------------IPEHWLIYPE-----------
186 --PPESMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK
187 --TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG
188 --KMTHGKAIAMIIFIYLYATPW-VVACYTESWG-----RFVPEGYLTSCTFDYLTDNF-
189 -DTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKKMNVDSLR-------
190 ------------------------------------------------------------
191 ------------------------------------------------------------
192 SNVDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAF--GDKTL-LTPGATMIPAC
193 TCKMVACIDPFVYAISHPRYRMELQKRCPWL--AISEKAPE-------SRAAISTSTTQE
194 Q-----------------------------------------------------------
195 -----------------------------------QQTTAA
196 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
197 ME------PLCNASEPPLRPEAR-SSGNGD-------LQFLGWNVPPDQIQ---Y-----
198 ---------------------------------------IPEHWLTQLE-----------
199 --PPASMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK
200 --APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR
201 --NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDNF-
202 -DTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKKMNVESLR-------
203 ------------------------------------------------------------
204 ------------------------------------------------------------
205 SNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF--GDKSL-LTQGATMIPAC
206 TCKLVACIDPFVYAISHPRYRLELQKRCPWL--GVNEKSGE-------ISSAQSTTTQEQ
207 ------------------------------------------------------------
208 -----------------------------------QQTTAA
209 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
210 MD------ALCNASEPPLRPEARMSSGSDE-------LQFLGWNVPPDQIQ---Y-----
211 ---------------------------------------IPEHWLTQLE-----------
212 --PPASMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK
213 --APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR
214 --NMTFTKAVIMNIIIWLYCTPW-VVLPLTQFWD-----RFVPEGYLTSCSFDYLSDNF-
215 -DTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKKMNVESLR-------
216 ------------------------------------------------------------
217 ------------------------------------------------------------
218 SNVDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF--GDKSL-LTPGATMIPAC
219 TCKLVACIEPFVYAISHPRYRMELQKRCPWL--GVNEKSGE-------ASSAQSTTTQEQ
220 T-----------------------------------------------------------
221 -----------------------------------QQTSAA
222 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
223 MT-----------NATGPQMAYYGAASMDFGYPE---GVSIVDFVRPEIKP---Y-----
224 ---------------------------------------VHQHWYNYPP-----------
225 --VNPMWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTT
226 N-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG
227 P-KLTTGKAVVFALISWVIAIGC-ALPPFF-GWG-----NYILEGILDSCSYDYLTQDF-
228 -NTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKKMNVSTLR-------
229 ------------------------------------------------------------
230 ------------------------------------------------------------
231 S-NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVM--GDTSG-ITPLVSTLPAL
232 LAKSCSCYNPFVYAISHPKYRLAITQHLPWF--CVHETETK-------SNDDSQSNSTVA
233 Q-----------------------------------------------------------
234 --------------------------------------DKA
235 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
236 MA-----------NVTGPQMAFYGSGAATFGYPE---GMTVADFVPDRVKH---M-----
237 ---------------------------------------VLDHWYNYPP-----------
238 --VNPMWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTT
239 N-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG
240 P-KLTQGKATFMCGLAWVISVGW-SLPPFF-GWG-----SYTLEGILDSCSYDYFTRDM-
241 -NTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKKMNVTNLR-------
242 ------------------------------------------------------------
243 ------------------------------------------------------------
244 S-NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLL--GNAEG-ITPLLTTLPAL
245 LAKSCSCYNPFVYAISHPKFRLAITQHLPWF--CVHEKDPN-------DVEENQSSNTQT
246 Q-----------------------------------------------------------
247 --------------------------------------EKS
248 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
249 ME-----SFAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH---L-----
250 ---------------------------------------ISPYWNQFPA-----------
251 --MDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
252 N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
253 R-PMTIPLALGKM---------------------------YVPEGNLTSCGIDYLERDW-
254 -NPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR-------
255 ------------------------------------------------------------
256 ------------------------------------------------------------
257 S-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGAC
258 FAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----DAQSQA-TASEA
259 E-----------------------------------------------------------
260 --------------------------------------SKA
261 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
262 ME-----SFAVAAAQLGPHFA-----PLS--------NGSVVDKVTPDMAH---L-----
263 ---------------------------------------ISPYWNQFPA-----------
264 --MDPIWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
265 N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
266 R-PMTIPLALGKIAYIWFMSSIW-CLAPAF-GWS-----RYVPEGNLTSCGIDYLERDW-
267 -NPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR-------
268 ------------------------------------------------------------
269 ------------------------------------------------------------
270 S-SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGAC
271 FAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----DAQSQA-TASEA
272 E-----------------------------------------------------------
273 --------------------------------------SKA
274 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
275 MD-----SFAAVATQLGPQFA-----APS--------NGSVVDKVTPDMAH---L-----
276 ---------------------------------------ISPYWDQFPA-----------
277 --MDPIWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMIT
278 N-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG
279 R-PMTIPLALGKIAYIWFMSTIWCCLAPVF-GWS-----RYVPEGNLTSCGIDYLERDW-
280 -NPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKKMNVKSLR-------
281 ------------------------------------------------------------
282 ------------------------------------------------------------
283 S-SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLF--KF-EG-LTPLNTIWGAC
284 FAKSAACYNPIVYGISHPKYRLALKEKCPCC--VFGKVDDGKSS----EAQSQA-TTSEA
285 E-----------------------------------------------------------
286 --------------------------------------SKA
287 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
288 MERSHLPETPFDLAHSGPRFQ-----AQSSG------NGSVLDNVLPDMAH---L-----
289 ---------------------------------------VNPYWSRFAP-----------
290 --MDPMMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS
291 Q-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING
292 T-PMTIKTSIMKILFIWMMAVFW-TVMPLI-GWS-----AYVPEGNLTACSIDYMTRMW-
293 -NPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKKMNVKSLR-------
294 ------------------------------------------------------------
295 ------------------------------------------------------------
296 S-SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF--KI-DG-LTPLTTIWGAT
297 FAKTSAVYNPIVYGISHPKYRIVLKEKCPMC--VFGNTDEPKPD----APASDTETTSEA
298 D-----------------------------------------------------------
299 --------------------------------------SKA
300 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
301 MERSLLPEPPLAMALLGPRFE-----AQTGG------NRSVLDNVLPDMAP---L-----
302 ---------------------------------------VNPHWSRFAP-----------
303 --MDPTMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMAS
304 Q-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING
305 T-PMTIKTSIMKIAFIWMMAVFW-TIMPLI-GWS-----SYVPEGNLTACSIDYMTRQW-
306 -NPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKKMNVKSLR-------
307 ------------------------------------------------------------
308 ------------------------------------------------------------
309 S-SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLF--KI-DG-LTPLTTIWGAT
310 FAKTSAVYNPIVYGISHPNDRLVLKEKCPMC--VCGTTDEPKPD----APPSDTETTSEA
311 E-----------------------------------------------------------
312 --------------------------------------SKD
313 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
314 MI-----------AVSGPSYE-----AFSYGGQARFNNQTVVDKVPPDMLH---L-----
315 ---------------------------------------IDANWYQYPP-----------
316 --LNPMWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFC
317 M-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG
318 K-PLSINGALIRIIAIWLFSLGW-TIAPMF-GWN-----RYVPEGNMTACGTDYFNRGL-
319 -LSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKKMNVASLR-------
320 ------------------------------------------------------------
321 ------------------------------------------------------------
322 S-SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIF--NL-VK-ISPLFTIWGSL
323 FAKANAVYNPIVYGISHPKYRAALFAKFPSL--ACAA--EPSSD----AVSTTSGTTTVT
324 D-----------------------------------------------------------
325 -----------------------------------NEKSNA
326 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
327 MA------------------NQLSYSSLGWPYQP---NASVVDTMPKEMLY---M-----
328 ---------------------------------------IHEHWYAFPP-----------
329 --MNPLWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAF
330 M-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA
331 A-PLTHKKATLLLLFVWIWSGGW-TILPFF-GWS-----RYVPEGNLTSCTVDYLTKDW-
332 -SSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKKMNVASLR-------
333 ------------------------------------------------------------
334 ------------------------------------------------------------
335 ANADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVF--SSGTR-LTPLATIWGSV
336 FAKANSCYNPIVYGISHPRYKAALYQRFPSL--ACGSGESGSDV----KSEASATTTMEE
337 K-----------------------------------------------------------
338 -----------------------------------PKIPEA
339 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
340 MV------------------ESTTLVNQTWWYNPTVD-----------------------
341 ---------------------------------------IHPHWAKFDP-----------
342 --IPDAVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAI
343 NGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAA
344 SKKMSHRRAFLMIIFVWMWSIVW-SVGPVF-NWG-----AYVPEGILTSCSFDYLSTDP-
345 -STRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKRLNAKELR-------
346 ------------------------------------------------------------
347 ------------------------------------------------------------
348 --KAQAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQF--GPAEW-VTPYAAELPVL
349 FAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECED----ANDAEEEVVASE
350 R--GGESRDAAQMKEMMAMMQKMQAQQAAYQP---PPPPQGYPPQGYPPQGAYPPPQGYP
351 PQGYPPQGYPPQGYPPQGAPPQVEAPQGAPPQGVDNQAYQA
352 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
353 MG------------------RDLR-DNETWWYNPSIV-----------------------
354 ---------------------------------------VHPHWREFDQ-----------
355 --VPDAVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLV
356 NGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAA
357 SKKMSHRRAFIMIIFVWLWSVLW-AIGPIF-GWG-----AYTLEGVLCNCSFDYISRDS-
358 -TTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKRLNAKELR-------
359 ------------------------------------------------------------
360 ------------------------------------------------------------
361 --KAQAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQF--GPLEW-VTPYAAQLPVM
362 FAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETED----DKDAETEIPAGE
363 SSDAAPSADAAQMKEMMAMMQKMQQQQAAYPPQGYAPPPQGYPPQGYPPQGY--PPQGYP
364 PQGYPP---PPQGAPPQGAPP------AAPPQGVDNQAYQA
365 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
366 MMD-----------------VNSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGADPVAGS
367 WAPHLLS------------------------EVTAS---PAPTW---DAPPDNASGCGEQ
368 INYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVA
369 V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
370 PVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF------
371 ----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFP
372 RVEPDSVIALNG------------------------------------------------
373 ----IVKLQKE------------------VEECAN------------------LSRLLKH
374 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLW
375 LGYANSLINPFIYAFFNRDLRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPE
376 RPEFV-------------------------------------------------------
377 ---------------------------LQNADYCRKKGHDS
378 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
379 M-----------------------------------------------------------
380 --PHLLS---------------------GFLEVTAS---PAPTW---DAPPDNVSGCGEQ
381 INYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA
382 V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
383 PVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF------
384 ----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFP
385 RVQPESVISLNG------------------------------------------------
386 ----VVKLQKE------------------VEECAN------------------LSRLLKH
387 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLW
388 LGYANSLINPFIYAFFNRDLRPTSRSLL-----QCQYRNINRKLSAAGMHEALKLAERPE
389 RSEFV-------------------------------------------------------
390 ---------------------------LQNSDHCGKKGHDT
391 > 31=p A47425 serotonin receptor 5HT-7 - rat
392 M-----------------------------------------------------------
393 --PHLLS---------------------GFLEVTAS---PAPTW---DAPPDNVSGCGEQ
394 INYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVA
395 V-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTY
396 PVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWA-----QNVNDDKVCLISQDF------
397 ----GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKF--------------PGFP
398 RVQPESVISLNG------------------------------------------------
399 ----VVKLQKE------------------VEECAN------------------LSRLLKH
400 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLW
401 LGYANSLINPFIYAFFNRDLRTTYRSLL-----QCQYRNINRKLSAAGMHEALKLAERPE
402 RSEFV-------------------------------------------------------
403 ---------------------------LQNSDHCGKKGHDT
404 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
405 M-----------------------------------------------------------
406 --------------------DVLSPGQGNNTTSPPAPFETGGNTTGISD-----------
407 --VTVSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL
408 V-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDY
409 VNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTP---EDRSDPDACTISKDH------
410 ----GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVKKVEKTGADTRHGASPAPQ
411 PKK---------SVNGESGSRNWRLGVESKAGGALCANGAVRQGDDGAALEVIEVHRVGN
412 SKEHLPLPSEAGPTPCAPASFERKNERNA-------------------------------
413 EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPTLLGAIINW
414 LGYSNSLLNPVIYAYFNKDFQNAFKKII-----KCKF-----------------------
415 ------------------------------------------------------------
416 --------------------------------------CRQ
417 > 33=p A35181 serotonin receptor class 1A - rat
418 M-----------------------------------------------------------
419 --------------------DVFSFGQGNNTTASQEPFGTGGNVTSISD-----------
420 --VTFSYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVL
421 V-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDY
422 VNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTP---EDRSDPDACTISKDH------
423 ----GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRKTVRKVEKKGAGTSLGTSSAPP
424 PKK---------SLNGQPGSGDWRRCAENRAVGTPCTNGAVRQGDDEATLEVIEVHRVGN
425 SKEHLPLPSESGSNSYAPACLERKNERNA-------------------------------
426 EAKRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MPALLGAIINW
427 LGYSNSLLNPVIYAYFNKDFQNAFKKII-----KCKF-----------------------
428 ------------------------------------------------------------
429 --------------------------------------CRR
430 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
431 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
432 HSSRSRD-----------------NASANDTSATNM---TDDRYWSLTV-----------
433 --YSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL
434 V-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDY
435 IRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NNDPDKTGTCIISQDK------
436 ----GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASP
437 KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSS
438 SSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-------------
439 RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF--VDPEG-IPPFARSFVLW
440 LGYFNSLLNPIIYTIFSPEFRSAFQKIL-----FGKY-----------------------
441 ------------------------------------------------------------
442 ------------------------------------RRGHR
443 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
444 MANFTFGDLALDVARMGGLASTPSGLRSTGLTTPGLSPTGLVTSDFNDSYGLTGQFINGS
445 HSSRSRD-----------------NASANDTSATNM---TDDRYWSLTV-----------
446 --YSHEHLVLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVL
447 V-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDY
448 IRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NNDPDKTGTCIISQDK------
449 ----GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASP
450 KTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKKNRAKKLPENANGVNSNSS
451 SSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS-------------
452 RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF--VDPEG-IPPFARSFVLW
453 LGYFNSLLNPIIYTIFSPEFRSAFQKIL-----FGKY-----------------------
454 ------------------------------------------------------------
455 ------------------------------------RRGHR
456 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
457 M--------------------------------------------------------EGA
458 EGQEELDWEALYLRLPLQNCSWNSTGWEPNWNVTVV---PNTTWWQASAPFDTP------
459 --AALVRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACL
460 V-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDY
461 IHASTAKRVGMMIACVWTVSFFV-CIAQLL-GWKDPDWNQRVSEDLRCVVSQDV------
462 ----GYQIFATASSFYVPVLIILILYWRIYQTARKRIRRRRGATARGGV--------GPP
463 PVPAGGALVAGGGSGG------------------------------------IAAAVVAV
464 IGRPLPTISETTTTGFTNVSSNNTSPE--KQSCANGLEADPPTTGYGAVAAAYYPSLVRR
465 KPKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT---CDCE-VSPVLTSLSLW
466 LGYFNSTLNPVIYTVFSPEFRHAFQRLL-----CGRR-----------------------
467 ------------------------------------------------------------
468 ---------------------------------VRRRRAPQ
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