import java.util.Arrays;
import java.util.List;
+import jalview.bin.Cache;
+
/**
* A simple way of bijectively mapping a non-contiguous linear range to another
* non-contiguous linear range.
*/
public MapList()
{
- fromShifts = new ArrayList<int[]>();
- toShifts = new ArrayList<int[]>();
+ fromShifts = new ArrayList<>();
+ toShifts = new ArrayList<>();
}
/**
{
return false;
}
- return Arrays
- .deepEquals(fromShifts.toArray(), obj.fromShifts.toArray())
- && Arrays
- .deepEquals(toShifts.toArray(), obj.toShifts.toArray());
+ return Arrays.deepEquals(fromShifts.toArray(), obj.fromShifts.toArray())
+ && Arrays.deepEquals(toShifts.toArray(),
+ obj.toShifts.toArray());
}
/**
{
int hashCode = 31 * fromRatio;
hashCode = 31 * hashCode + toRatio;
- hashCode = 31 * hashCode + fromShifts.toArray().hashCode();
- hashCode = 31 * hashCode + toShifts.toArray().hashCode();
+ for (int[] shift : fromShifts)
+ {
+ hashCode = 31 * hashCode + shift[0];
+ hashCode = 31 * hashCode + shift[1];
+ }
+ for (int[] shift : toShifts)
+ {
+ hashCode = 31 * hashCode + shift[0];
+ hashCode = 31 * hashCode + shift[1];
+ }
+
return hashCode;
}
/**
* Constructor given from and to ranges as [start1, end1, start2, end2,...].
- * If any end is equal to the next start, the ranges will be merged. There is
- * no validation check that the ranges do not overlap each other.
+ * There is no validation check that the ranges do not overlap each other.
*
* @param from
* contiguous regions as [start1, end1, start2, end2, ...]
this.toRatio = toRatio;
fromLowest = Integer.MAX_VALUE;
fromHighest = Integer.MIN_VALUE;
- int added = 0;
for (int i = 0; i < from.length; i += 2)
{
*/
fromLowest = Math.min(fromLowest, Math.min(from[i], from[i + 1]));
fromHighest = Math.max(fromHighest, Math.max(from[i], from[i + 1]));
- if (added > 0 && from[i] == fromShifts.get(added - 1)[1])
- {
- /*
- * this range starts where the last ended - just extend it
- */
- fromShifts.get(added - 1)[1] = from[i + 1];
- }
- else
- {
- fromShifts.add(new int[] { from[i], from[i + 1] });
- added++;
- }
+ fromShifts.add(new int[] { from[i], from[i + 1] });
}
toLowest = Integer.MAX_VALUE;
toHighest = Integer.MIN_VALUE;
- added = 0;
for (int i = 0; i < to.length; i += 2)
{
toLowest = Math.min(toLowest, Math.min(to[i], to[i + 1]));
toHighest = Math.max(toHighest, Math.max(to[i], to[i + 1]));
- if (added > 0 && to[i] == toShifts.get(added - 1)[1])
- {
- toShifts.get(added - 1)[1] = to[i + 1];
- }
- else
- {
- toShifts.add(new int[] { to[i], to[i + 1] });
- added++;
- }
+ toShifts.add(new int[] { to[i], to[i + 1] });
}
}
fromHighest = Integer.MIN_VALUE;
for (int[] range : fromRange)
{
+ if (range.length != 2)
+ {
+ // throw new IllegalArgumentException(range);
+ Cache.log.error("Invalid format for fromRange "
+ + Arrays.toString(range) + " may cause errors");
+ }
fromLowest = Math.min(fromLowest, Math.min(range[0], range[1]));
fromHighest = Math.max(fromHighest, Math.max(range[0], range[1]));
}
toHighest = Integer.MIN_VALUE;
for (int[] range : toRange)
{
+ if (range.length != 2)
+ {
+ // throw new IllegalArgumentException(range);
+ Cache.log.error("Invalid format for toRange "
+ + Arrays.toString(range) + " may cause errors");
+ }
toLowest = Math.min(toLowest, Math.min(range[0], range[1]));
toHighest = Math.max(toHighest, Math.max(range[0], range[1]));
}
/**
* Consolidates a list of ranges so that any contiguous ranges are merged.
* This assumes the ranges are already in start order (does not sort them).
+ * <p>
+ * The main use case for this method is when mapping cDNA sequence to its
+ * protein product, based on CDS feature ranges which derive from spliced
+ * exons, but are contiguous on the cDNA sequence. For example
+ * <pre>
+ * CDS 1-20 // from exon1
+ * CDS 21-35 // from exon2
+ * CDS 36-71 // from exon3
+ * 'coalesce' to range 1-71
+ * </pre>
*
* @param ranges
* @return the same list (if unchanged), else a new merged list, leaving the
*/
public static List<int[]> coalesceRanges(final List<int[]> ranges)
{
- if (ranges == null || ranges.size() < 2) {
+ if (ranges == null || ranges.size() < 2)
+ {
return ranges;
}
boolean changed = false;
- List<int[]> merged = new ArrayList<int[]>();
+ List<int[]> merged = new ArrayList<>();
int[] lastRange = ranges.get(0);
int lastDirection = lastRange[1] >= lastRange[0] ? 1 : -1;
lastRange = new int[] { lastRange[0], lastRange[1] };
merged.add(lastRange);
boolean first = true;
-
+
for (final int[] range : ranges)
{
if (first)
first = false;
continue;
}
- if (range[0] == lastRange[0] && range[1] == lastRange[1])
- {
- // drop duplicate range
- changed = true;
- continue;
- }
-
- /*
- * drop this range if it lies within the last range
- */
- if ((lastDirection == 1 && range[0] >= lastRange[0]
- && range[0] <= lastRange[1] && range[1] >= lastRange[0] && range[1] <= lastRange[1])
- || (lastDirection == -1 && range[0] <= lastRange[0]
- && range[0] >= lastRange[1]
- && range[1] <= lastRange[0] && range[1] >= lastRange[1]))
- {
- changed = true;
- continue;
- }
int direction = range[1] >= range[0] ? 1 : -1;
* if next range is in the same direction as last and contiguous,
* just update the end position of the last range
*/
- boolean sameDirection = range[1] == range[0] || direction == lastDirection;
+ boolean sameDirection = range[1] == range[0]
+ || direction == lastDirection;
boolean extending = range[0] == lastRange[1] + lastDirection;
- boolean overlapping = (lastDirection == 1 && range[0] >= lastRange[0] && range[0] <= lastRange[1])
- || (lastDirection == -1 && range[0] <= lastRange[0] && range[0] >= lastRange[1]);
- if (sameDirection && (overlapping || extending))
+ if (sameDirection && extending)
{
lastRange[1] = range[1];
changed = true;
lastDirection = (range[1] == range[0]) ? lastDirection : direction;
}
}
-
+
return changed ? merged : ranges;
}
{
return null;
}
- List<int[]> ranges = new ArrayList<int[]>();
+ List<int[]> ranges = new ArrayList<>();
if (fs <= fe)
{
intv = fs;
// TODO not used - remove?
if (local)
{
- return ((getFromLowest() >= map.getFromLowest() && getFromHighest() <= map
- .getFromHighest()) || (getFromLowest() <= map.getFromLowest() && getFromHighest() >= map
- .getFromHighest()));
+ return ((getFromLowest() >= map.getFromLowest()
+ && getFromHighest() <= map.getFromHighest())
+ || (getFromLowest() <= map.getFromLowest()
+ && getFromHighest() >= map.getFromHighest()));
}
else
{
- return ((getToLowest() >= map.getToLowest() && getToHighest() <= map
- .getToHighest()) || (getToLowest() <= map.getToLowest() && getToHighest() >= map
- .getToHighest()));
+ return ((getToLowest() >= map.getToLowest()
+ && getToHighest() <= map.getToHighest())
+ || (getToLowest() <= map.getToLowest()
+ && getToHighest() >= map.getToHighest()));
}
}
*/
public boolean isFromForwardStrand()
{
+ return isForwardStrand(getFromRanges());
+ }
+
+ /**
+ * Returns true if mapping is to forward strand, false if to reverse strand.
+ * Result is just based on the first 'to' range that is not a single position.
+ * Default is true unless proven to be false. Behaviour is not well defined if
+ * the mapping has a mixture of forward and reverse ranges.
+ *
+ * @return
+ */
+ public boolean isToForwardStrand()
+ {
+ return isForwardStrand(getToRanges());
+ }
+
+ /**
+ * A helper method that returns true unless at least one range has start >
+ * end. Behaviour is undefined for a mixture of forward and reverse ranges.
+ *
+ * @param ranges
+ * @return
+ */
+ private boolean isForwardStrand(List<int[]> ranges)
+ {
boolean forwardStrand = true;
- for (int[] range : getFromRanges())
+ for (int[] range : ranges)
{
if (range[1] > range[0])
{
return forwardStrand;
}
+ /**
+ *
+ * @return true if from, or to is a three to 1 mapping
+ */
+ public boolean isTripletMap()
+ {
+ return (toRatio == 3 && fromRatio == 1)
+ || (fromRatio == 3 && toRatio == 1);
+ }
+
+ /**
+ * Returns a map which is the composite of this one and the input map. That
+ * is, the output map has the fromRanges of this map, and its toRanges are the
+ * toRanges of this map as transformed by the input map.
+ * <p>
+ * Returns null if the mappings cannot be traversed (not all toRanges of this
+ * map correspond to fromRanges of the input), or if this.toRatio does not
+ * match map.fromRatio.
+ *
+ * <pre>
+ * Example 1:
+ * this: from [1-100] to [501-600]
+ * input: from [10-40] to [60-90]
+ * output: from [10-40] to [560-590]
+ * Example 2 ('reverse strand exons'):
+ * this: from [1-100] to [2000-1951], [1000-951] // transcript to loci
+ * input: from [1-50] to [41-90] // CDS to transcript
+ * output: from [10-40] to [1960-1951], [1000-971] // CDS to gene loci
+ * </pre>
+ *
+ * @param map
+ * @return
+ */
+ public MapList traverse(MapList map)
+ {
+ if (map == null)
+ {
+ return null;
+ }
+
+ /*
+ * compound the ratios by this rule:
+ * A:B with M:N gives A*M:B*N
+ * reduced by greatest common divisor
+ * so 1:3 with 3:3 is 3:9 or 1:3
+ * 1:3 with 3:1 is 3:3 or 1:1
+ * 1:3 with 1:3 is 1:9
+ * 2:5 with 3:7 is 6:35
+ */
+ int outFromRatio = getFromRatio() * map.getFromRatio();
+ int outToRatio = getToRatio() * map.getToRatio();
+ int gcd = MathUtils.gcd(outFromRatio, outToRatio);
+ outFromRatio /= gcd;
+ outToRatio /= gcd;
+
+ List<int[]> toRanges = new ArrayList<>();
+ for (int[] range : getToRanges())
+ {
+ int[] transferred = map.locateInTo(range[0], range[1]);
+ if (transferred == null || transferred.length % 2 != 0)
+ {
+ return null;
+ }
+
+ /*
+ * convert [start1, end1, start2, end2, ...]
+ * to [[start1, end1], [start2, end2], ...]
+ */
+ for (int i = 0; i < transferred.length;)
+ {
+ toRanges.add(new int[] { transferred[i], transferred[i + 1] });
+ i += 2;
+ }
+ }
+
+ return new MapList(getFromRanges(), toRanges, outFromRatio, outToRatio);
+ }
+
+ /**
+ * Answers true if the mapping is from one contiguous range to another, else
+ * false
+ *
+ * @return
+ */
+ public boolean isContiguous()
+ {
+ return fromShifts.size() == 1 && toShifts.size() == 1;
+ }
+
+ /**
+ * Returns the [start, end...] positions in the range mapped from, that are
+ * mapped to by part or all of the given begin-end of the range mapped to.
+ * Returns null if begin-end does not overlap any position mapped to.
+ *
+ * @param begin
+ * @param end
+ * @return
+ */
+ public int[] getOverlapsInFrom(final int begin, final int end)
+ {
+ int[] overlaps = MappingUtils.findOverlap(toShifts, begin, end);
+
+ return overlaps == null ? null : locateInFrom(overlaps[0], overlaps[1]);
+ }
+
+ /**
+ * Returns the [start, end...] positions in the range mapped to, that are
+ * mapped to by part or all of the given begin-end of the range mapped from.
+ * Returns null if begin-end does not overlap any position mapped from.
+ *
+ * @param begin
+ * @param end
+ * @return
+ */
+ public int[] getOverlapsInTo(final int begin, final int end)
+ {
+ int[] overlaps = MappingUtils.findOverlap(fromShifts, begin, end);
+
+ return overlaps == null ? null : locateInTo(overlaps[0], overlaps[1]);
+ }
}
git://source.jalview.org / jalview.git / blobdiff