1 > 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
2 M-----------------------------------------------------------
3 -----------------------------------NGTE--GDNFYVPF-----------
4 ---------------------------------------------SNKTGLARSPYEYPQ
5 Y-YLAEPW------------K--------------------------------YSALAAY
6 MFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANLFMVLFG-FTVTMYTS-MN-
7 GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVICKPMGN-FRFGNTHAIMGV
8 AFTWIMALAC-AAPPLVG-WSRYIP-------EGM----QCSCGPDYYTLNPNFNNESYV
9 VYMFVVHFLVPFVIIFFCYGRLLCTV----KE----------------------------
10 ------------------------------------------------------------
11 ----------------------------------------------AAAAQQE-------
12 ------------------------------SASTQKAEKEVTRMVVLMVIGFLVCWVPYA
13 SVAFYIFT-HQG-S--DFGATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLC-C-
14 --GKNP-------------------LGDDE--SGASTSKT-E--VSSVS-TSPV------
15 ------------------------------------------------------------
16 -------------------SP-A---
17 > 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
18 M-----------------------------------------------------------
19 -----------------------------------NGTE--GPNFYVPF-----------
20 ---------------------------------------------SNITGVVRSPFEQPQ
21 Y-YLAEPW------------Q--------------------------------FSMLAAY
22 MFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGG-FTTTLYTS-LH-
23 GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVCKPMSN-FRFGENHAIMGV
24 AFTWVMALAC-AAPPLVG-WSRYIP-------EGM----QCSCGIDYYTLKPEVNNESFV
25 IYMFVVHFTIPMIVIFFCYGQLVFTV----KE----------------------------
26 ------------------------------------------------------------
27 ----------------------------------------------AAAQQQE-------
28 ------------------------------SATTQKAEKEVTRMVIIMVIFFLICWLPYA
29 SVAMYIFT-HQG-S--NFGPIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLC-C-
30 --GKNP-------------------LGDDE--ASATASKT-E--------TSQV------
31 ------------------------------------------------------------
32 -------------------AP-A---
33 > 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
34 M-----------------------------------------------------------
35 -----------------------------------NGTE--GINFYVPM-----------
36 ---------------------------------------------SNKTGVVRSPFEYPQ
37 Y-YLAEPW------------K--------------------------------YRLVCCY
38 IFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADLFMACFG-FTVTFYTA-WN-
39 GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVCKPMGN-FRFSATHAMMGI
40 AFTWVMAFSC-AAPPLFG-WSRYMP-------EGM----QCSCGPDYYTHNPDYHNESYV
41 LYMFVIHFIIPVVVIFFSYGRLICKV----RE----------------------------
42 ------------------------------------------------------------
43 ----------------------------------------------AAAQQQE-------
44 ------------------------------SATTQKAEKEVTRMVILMVLGFMLAWTPYA
45 VVAFWIFT-NKG-A--DFTATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTIC-C-
46 --GKNP-------------------FGDEDVSSTVSQSKT-E--VSSVS-SSQV------
47 ------------------------------------------------------------
48 -------------------SP-A---
49 > 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
50 M-----------------------------------------------------------
51 -----------------------------------NGTE--GKNFYVPM-----------
52 ---------------------------------------------SNRTGLVRSPFEYPQ
53 Y-YLAEPW------------Q--------------------------------FKILALY
54 LFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGTIMVCFG-FTVTFYTA-IN-
55 GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSSHAFAGI
56 AFTWVMALAC-AAPPLFG-WSRYIP-------EGM----QCSCGPDYYTLNPDYNNESYV
57 IYMFVCHFILPVAVIFFTYGRLVCTV----KA----------------------------
58 ------------------------------------------------------------
59 ----------------------------------------------AAAQQQD-------
60 ------------------------------SASTQKAEREVTKMVILMVFGFLIAWTPYA
61 TVAAWIFF-NKG-A--DFSAKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIF-C-
62 --GKNP-------------------LGDDE-SSTVSTSKT-E--VSS------V------
63 ------------------------------------------------------------
64 -------------------SP-A---
65 > 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
66 M-----------------------------------------------------------
67 -----------------------------------NGTE--GNNFYVPL-----------
68 ---------------------------------------------SNRTGLVRSPFEYPQ
69 Y-YLAEPW------------Q--------------------------------FKLLAVY
70 MFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGAIMVCFG-FTVTFYTA-IN-
71 GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVCKPMGS-FKFSSTHASAGI
72 AFTWVMAMAC-AAPPLVG-WSRYIP-------EGI----QCSCGPDYYTLNPEYNNESYV
73 LYMFICHFILPVTIIFFTYGRLVCTV----KA----------------------------
74 ------------------------------------------------------------
75 ----------------------------------------------AAAQQQD-------
76 ------------------------------SASTQKAEREVTKMVILMVLGFLVAWTPYA
77 TVAAWIFF-NKG-A--AFSAQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLF-C-
78 --GKNP-------------------LGDEE-SSTVSTSKT-E--VSS------V------
79 ------------------------------------------------------------
80 -------------------SP-A---
81 > 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
82 M-----------------------------------------------------------
83 -----------------------------------KQVPEFHEDFYIPIPL---------
84 -------------------------------------------DINNLS--AYSPFLVPQ
85 D-HLGNQG------------I--------------------------------FMAMSVF
86 MFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANLFVAIFG-SPLSFYSF-FN-
87 RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVICKPLGN-FTFKTPHAIAGC
88 ILPWISALAA-SLPPLFG-WSRYIP-------EGL----QCSCGPDWYTTNNKYNNESYV
89 MFLFCFCFAVPFGTIVFCYGQLLITL----KL----------------------------
90 ------------------------------------------------------------
91 ----------------------------------------------AAKAQAD-------
92 ------------------------------SASTQKAEREVTKMVVVMVLGFLVCWAPYA
93 SFSLWIVS-HRG-E--EFDLRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMM-KMV-C-
94 --GKN--------------------IEEDE--ASTSSQVT-Q--VSS------V------
95 ------------------------------------------------------------
96 -------------------APEK---
97 > 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
98 M-----------------------------------------------------------
99 -----------------------------------RKMS--EEEFYL---F---------
100 ---------------------------------------------KNISSV--GPWDGPQ
101 Y-HIAPVW------------A--------------------------------FYLQAAF
102 MGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFS-VFPVFVAS-CN-
103 GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGN-FRFSSKHALTVV
104 LATWTIGIGV-SIPPFFG-WSRFIP-------EGL----QCSCGPDWYTVGTKYRSESYT
105 WFLFIFCFIVPLSLICFSYTQLLRAL----KA----------------------------
106 ------------------------------------------------------------
107 ----------------------------------------------VAAQQQE-------
108 ------------------------------SATTQKAEREVSRMVVVMVGSFCVCYVPYA
109 AFAMYMVN-NRN-H--GLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIM-KMV-C-
110 --GKA--------------------MTDES--DTCSSQKT-E--VSTVS-STQV------
111 ------------------------------------------------------------
112 -------------------GP-N---
113 > 8=opsin, greensensitive human (fragment) S07060
114 ------------------------------------------------------------
115 ------------------------------------------------------------
116 ------------------------------------------------------------
117 ------------------------------------------------------------
118 ---------------------------------------DLAETVIA-STISIVNQ-VS-
119 GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGI
120 AFSWIWAAVW-TAPPIFG-WSRYWP-------HGL----KTSCGPDVFSGSSYPGVQSYM
121 IVLMVTCCITPLSIIVLCYLQVWLAI----RA----------------------------
122 ------------------------------------------------------------
123 ----------------------------------------------VAKQQKE-------
124 ------------------------------SESTQKAEKEVTRMVVVMVLAFC-------
125 ------------------------------------------------------------
126 ------------------------------------------------------------
127 ------------------------------------------------------------
128 --------------------------
129 > 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
130 M--------------AQQWSLQRLAGRHPQDSYE--------------------------
131 -----------------------------------DSTQ--SSIFTYTN-----------
132 ---------------------------------------------SNST---RGPFEGPN
133 Y-HIAPRW------------V--------------------------------YHLTSVW
134 MIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISVVNQ-VY-
135 GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGN-VRFDAKLAIVGI
136 AFSWIWAAVW-TAPPIFG-WSRYWP-------HGL----KTSCGPDVFSGSSYPGVQSYM
137 IVLMVTCCITPLSIIVLCYLQVWLAI----RA----------------------------
138 ------------------------------------------------------------
139 ----------------------------------------------VAKQQKE-------
140 ------------------------------SESTQKAEKEVTRMVVVMVLAFCFCWGPYA
141 FFACFAAA-NPG-Y--PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCIL-QLF---
142 --GKK--------------------VDDGS--ELSSASKT-E--VSSV---SSV------
143 ------------------------------------------------------------
144 -------------------SP-A---
145 > 10== Z68193 1 human Red Opsin <>[]
146 M--------------AQQWSLQRLAGRHPQDSYE--------------------------
147 -----------------------------------DSTQ--SSIFTYTN-----------
148 ---------------------------------------------SNST---RGPFEGPN
149 Y-HIAPRW------------V--------------------------------YHLTSVW
150 MIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIA-STISIVNQ-VS-
151 GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVCKPFGN-VRFDAKLAIVGI
152 AFSWIWSAVW-TAPPIFG-WSRYWP-------HGL----KTSCGPDVFSGSSYPGVQSYM
153 IVLMVTCCIIPLAIIMLCYLQVWLAI----RA----------------------------
154 ------------------------------------------------------------
155 ----------------------------------------------VAKQQKE-------
156 ------------------------------SESTQKAEKEVTRMVVVMIFAYCVCWGPYT
157 FFACFAAA-NPG-Y--AFHPLMAALPAYFAKSATIYNPVIYVFMNRQFRNCIL-QLF---
158 --GKK--------------------VDDGS--ELSSASKT-E--VSSV---SSV------
159 ------------------------------------------------------------
160 -------------------SP-A---
161 > 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
162 M--------------TEAWNVAVFAARRSRDD-D--------------------------
163 -----------------------------------DTTR--GSVFTYTN-----------
164 ---------------------------------------------TNNT---RGPFEGPN
165 Y-HIAPRW------------V--------------------------------YNLVSFF
166 MIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDLVETLVA-STISVFNQ-IF-
167 GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVCKPFGN-IKFDSKLAIIGI
168 VFSWVWAWGW-SAPPIFG-WSRYWP-------HGL----KTSCGPDVFSGSVELGCQSFM
169 LTLMITCCFLPLFIIIVCYLQVWMAI----RA----------------------------
170 ------------------------------------------------------------
171 ----------------------------------------------VAAQQKE-------
172 ------------------------------SESTQKAEREVSRMVVVMIVAFCICWGPYA
173 SFVSFAAA-NPG-Y--AFHPLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIM-QLF---
174 --GKK--------------------VDDGS--EASTTSRT-E--VSSVS-NSSV------
175 ------------------------------------------------------------
176 -------------------AP-A---
177 > 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
178 M--------------AA-WEAAFAARRRHEE--E--------------------------
179 -----------------------------------DTTR--DSVFTYTN-----------
180 ---------------------------------------------SNNT---RGPFEGPN
181 Y-HIAPRW------------V--------------------------------YNLTSVW
182 MIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADLGETVIA-STISVINQ-IS-
183 GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVCKPFGN-IKFDGKLAVAGI
184 LFSWLWSCAW-TAPPIFG-WSRYWP-------HGL----KTSCGPDVFSGSSDPGVQSYM
185 VVLMVTCCFFPLAIIILCYLQVWLAI----RA----------------------------
186 ------------------------------------------------------------
187 ----------------------------------------------VAAQQKE-------
188 ------------------------------SESTQKAEKEVSRMVVVMIVAYCFCWGPYT
189 FFACFAAA-NPG-Y--AFHPLAAALPAYFAKSATIYNPIIYVFMNRQFRNCIL-QLF---
190 --GKK--------------------VDDGS--EVST-SRT-E--VSSVS-NSSV------
191 ------------------------------------------------------------
192 -------------------SP-A---
193 > 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
194 M--------------S-----------------S--------------------------
195 -----------------------------------NSSQ--AP-----------------
196 ---------------------------------------------PNGT---PGPFDGPQ
197 WPYQAPQS------------T--------------------------------YVGVAVL
198 MGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADLLVTLCG-SSVSLSNN-IN-
199 GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVCKPLGD-FQFQRRHAVSGC
200 AFTWGWALLW-SAPPLLG-WSSYVP-------EGL----RTSCGPNWYTGGSNN--NSYI
201 LSLFVTCFVLPLSLILFSYTNLLLTL----RA----------------------------
202 ------------------------------------------------------------
203 ----------------------------------------------AAAQQKE-------
204 ------------------------------ADTTQRAEREVTRMVIVMVMAFLLCWLPYS
205 TFALVVAT-HKG-I--IIQPVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLL-EMLCCG
206 YQPQR--------------------TGKAS--PGTPGPHA-D--VTAAGLRNKV------
207 ------------------------------------------------------------
208 -------------------MP-AHPV
209 > 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
210 M--------------------------------ES-G-----------------------
211 -----------------------------------NVSS-----------SLFGNVSTAL
212 RPEA------------------RLSA---ETRLLGWNVPPEELR----------------
213 --HIPEHW------------LT---------YPEPPESM--------------NYLLGTL
214 YIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDFMMMVK--TPIFIYNS-FH-
215 QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVITRPMEG--KMTHGKAIAMI
216 IFIYMYATPW-VVACYTETWGRFVP-------EGY----LTSCTFDYLT--DNFDTRLFV
217 ACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------------------
218 ------------------------------------------------------------
219 ----------------------------------------------LRDQAKK--MNVES
220 L------------------------RS-NVDKNKETAEIRIAKAAITICFLFFCSWTPYG
221 VMSLIGAF-GDK-T--LLTPGATMIPACACKMVACIDPFVYAISHPRYRMELQ-------
222 --KRCP----WLALNE---KAPE--SSAVA--STSTTQEP-Q------------------
223 -------QT---------------------------------------------------
224 -------------------TA-A---
225 > 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
226 M--------------------------------EY-H-----------------------
227 -----------------------------------NVSS-----------VL-GNVSSVL
228 RPDA------------------RLSA---ESRLLGWNVPPDELR----------------
229 --HIPEHW------------LI---------YPEPPESM--------------NYLLGTL
230 YIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDFMMMIK--TPIFIYNS-FH-
231 QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVITRPMEG--KMTHGKAIAMI
232 IFIYLYATPW-VVACYTESWGRFVP-------EGY----LTSCTFDYLT--DNFDTRLFV
233 ACIFFFSFVCPTTMITYYYSQIVGHVFSHEKA----------------------------
234 ------------------------------------------------------------
235 ----------------------------------------------LRDQAKK--MNVDS
236 L------------------------RS-NVDKSKEAAEIRIAKAAITICFLFFASWTPYG
237 VMSLIGAF-GDK-T--LLTPGATMIPACTCKMVACIDPFVYAISHPRYRMELQ-------
238 --KRCP----WLAISE---KAPE--SRAAI--STSTTQEQ-Q------------------
239 -------QT---------------------------------------------------
240 -------------------TA-A---
241 > 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
242 M--------------------------------EPLC-----------------------
243 -----------------------------------NASE-----------PP-------L
244 RPEA------------------R-SSGNGDLQFLGWNVPPDQIQ----------------
245 --YIPEHW------------LT---------QLEPPASM--------------HYMLGVF
246 YIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIF--NS-FH-
247 RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMN
248 IIIWLYCTPW-VVLPLTQFWDRFVP-------EGY----LTSCSFDYLS--DNFDTRLFV
249 GTIFFFSFVCPTLMILYYYSQIVGHVFSHEKA----------------------------
250 ------------------------------------------------------------
251 ----------------------------------------------LREQAKK--MNVES
252 L------------------------RS-NVDKSKETAEIRIAKAAITICFLFFVSWTPYG
253 VMSLIGAF-GDK-S--LLTQGATMIPACTCKLVACIDPFVYAISHPRYRLELQ-------
254 --KRCP----WLGVNE---KSGE--ISSAQ--ST-TTQEQ-Q------------------
255 -------QT---------------------------------------------------
256 -------------------TA-A---
257 > 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
258 M--------------------------------DALC-----------------------
259 -----------------------------------NASE-----------PP-------L
260 RPEA------------------RMSSGSDELQFLGWNVPPDQIQ----------------
261 --YIPEHW------------LT---------QLEPPASM--------------HYMLGVF
262 YIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDLIMCLK--APIFIYNS-FH-
263 RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVITKPMNR--NMTFTKAVIMN
264 IIIWLYCTPW-VVLPLTQFWDRFVP-------EGY----LTSCSFDYLS--DNFDTRLFV
265 GTIFLFSFVVPTLMILYYYSQIVGHVFNHEKA----------------------------
266 ------------------------------------------------------------
267 ----------------------------------------------LREQAKK--MNVES
268 L------------------------RS-NVDKSKETAEIRIAKAAITICFLFFVSWTPYG
269 VMSLIGAF-GDK-S--LLTPGATMIPACTCKLVACIEPFVYAISHPRYRMELQ-------
270 --KRCP----WLGVNE---KSGE--ASSAQ--ST-TTQEQTQ------------------
271 -------QT---------------------------------------------------
272 -------------------SA-A---
273 > 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
274 M--------------------------------------------TNATGPQMAYYGAAS
275 MDFGYPE----------------------------GVSI-----------VD--------
276 ------------------------------------FVRPEIKP----------------
277 --YVHQHW------------YN---------YPPVNPMW--------------HYLLGVI
278 YLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDLIMLTTN-VPFFTYNC-FSG
279 GVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIICNGFNG-PKLTTGKAVVFA
280 LISWVIAIGC-ALPPFFG-WGNYIL-------EGI----LDSCSYDYLT--QDFNTFSYN
281 IFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAA----------------------------
282 ------------------------------------------------------------
283 ----------------------------------------------MRAQAKK--MNVST
284 L------------------------RS-N-EADAQRAEIRIAKTALVNVSLWFICWTPYA
285 LISLKGVM-GDT-S--GITPLVSTLPALLAKSCSCYNPFVYAISHPKYRLAIT-------
286 --QHLP----WFCVHE---TETKS-NDDSQ--SNSTVAQ---------------------
287 ------------------------------------------------------------
288 -------------------DK-A---
289 > 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
290 M--------------------------------------------ANVTGPQMAFYGSGA
291 ATFGYPE----------------------------GMTV-----------AD--------
292 ------------------------------------FVPDRVKH----------------
293 --MVLDHW------------YN---------YPPVNPMW--------------HYLLGVV
294 YLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDLIMLTTN-FPPFCYNC-FSG
295 GRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIICNGFNG-PKLTQGKATFMC
296 GLAWVISVGW-SLPPFFG-WGSYTL-------EGI----LDSCSYDYFT--RDMNTITYN
297 ICIFIFDFFLPASVIVFSYVFIVKAIFAHEAA----------------------------
298 ------------------------------------------------------------
299 ----------------------------------------------MRAQAKK--MNVTN
300 L------------------------RS-N-EAETQRAEIRIAKTALVNVSLWFICWTPYA
301 AITIQGLL-GNA-E--GITPLLTTLPALLAKSCSCYNPFVYAISHPKFRLAIT-------
302 --QHLP----WFCVHE---KDPND-VEENQ--SSNTQTQ---------------------
303 ------------------------------------------------------------
304 -------------------EK-S---
305 > 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
306 M--------------------------------E------SFAVAAAQLGPHFAPLS---
307 -----------------------------------NGSV-----------VD--------
308 ------------------------------------KVTPDMAH----------------
309 --LISPYW------------NQ---------FPAMDPIW--------------AKILTAY
310 MIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINL-YF-
311 ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKM
312 ----------------------YVP-------EGN----LTSCGIDYLE--RDWNPRSYL
313 IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
314 ------------------------------------------------------------
315 ----------------------------------------------MREQAKK--MNVKS
316 L------------------------RS-S-EDAEKSAEGKLAKVALVTITLWFMAWTPYL
317 VINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-------
318 --EKCP----CCVFGK---VDDGK-SSDAQ--SQATASEA-E------------------
319 ------------------------------------------------------------
320 -------------------SK-A---
321 > 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
322 M--------------------------------E------SFAVAAAQLGPHFAPLS---
323 -----------------------------------NGSV-----------VD--------
324 ------------------------------------KVTPDMAH----------------
325 --LISPYW------------NQ---------FPAMDPIW--------------AKILTAY
326 MIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINL-YF-
327 ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKI
328 AYIWFMSSIW-CLAPAFG-WSRYVP-------EGN----LTSCGIDYLE--RDWNPRSYL
329 IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
330 ------------------------------------------------------------
331 ----------------------------------------------MREQAKK--MNVKS
332 L------------------------RS-S-EDAEKSAEGKLAKVALVTITLWFMAWTPYL
333 VINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-------
334 --EKCP----CCVFGK---VDDGK-SSDAQ--SQATASEA-E------------------
335 ------------------------------------------------------------
336 -------------------SK-A---
337 > 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
338 M--------------------------------D------SFAAVATQLGPQFAAPS---
339 -----------------------------------NGSV-----------VD--------
340 ------------------------------------KVTPDMAH----------------
341 --LISPYW------------DQ---------FPAMDPIW--------------AKILTAY
342 MIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDFGIMITN-TPMMGINL-YF-
343 ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIVKGMAG-RPMTIPLALGKI
344 AYIWFMSTIWCCLAPVFG-WSRYVP-------EGN----LTSCGIDYLE--RDWNPRSYL
345 IFYSIFVYYIPLFLICYSYWFIIAAVSAHEKA----------------------------
346 ------------------------------------------------------------
347 ----------------------------------------------MREQAKK--MNVKS
348 L------------------------RS-S-EDADKSAEGKLAKVALVTISLWFMAWTPYL
349 VINCMGLF--KF-E--GLTPLNTIWGACFAKSAACYNPIVYGISHPKYRLALK-------
350 --EKCP----CCVFGK---VDDGK-SSEAQ--SQATTSEA-E------------------
351 ------------------------------------------------------------
352 -------------------SK-A---
353 > 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
354 M--------------------------------ER-SHLPETPFDLAHSGPRFQAQSSG-
355 -----------------------------------NGSV-----------LD--------
356 ------------------------------------NVLPDMAH----------------
357 --LVNPYW------------SR---------FAPMDPMM--------------SKILGLF
358 TLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINF-YY-
359 ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKI
360 LFIWMMAVFW-TVMPLIG-WSAYVP-------EGN----LTACSIDYMT--RMWNPRSYL
361 ITYSLFVYYTPLFLICYSYWFIIAAVAAHEKA----------------------------
362 ------------------------------------------------------------
363 ----------------------------------------------MREQAKK--MNVKS
364 L------------------------RS-S-EDCDKSAEGKLAKVALTTISLWFMAWTPYL
365 VICYFGLF--KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLK-------
366 --EKCP----MCVFGN---TDEPKPDAPAS--DTETTSEA-D------------------
367 ------------------------------------------------------------
368 -------------------SK-A---
369 > 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
370 M--------------------------------ER-SLLPEPPLAMALLGPRFEAQTGG-
371 -----------------------------------NRSV-----------LD--------
372 ------------------------------------NVLPDMAP----------------
373 --LVNPHW------------SR---------FAPMDPTM--------------SKILGLF
374 TLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDFCMMASQ-SPVMIINF-YY-
375 ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIVKGING-TPMTIKTSIMKI
376 AFIWMMAVFW-TIMPLIG-WSSYVP-------EGN----LTACSIDYMT--RQWNPRSYL
377 ITYSLFVYYTPLFMICYSYWFIIATVAAHEKA----------------------------
378 ------------------------------------------------------------
379 ----------------------------------------------MRDQAKK--MNVKS
380 L------------------------RS-S-EDCDKSAENKLAKVALTTISLWFMAWTPYL
381 IICYFGLF--KI-D--GLTPLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLK-------
382 --EKCP----MCVCGT---TDEPKPDAPPS--DTETTSEA-E------------------
383 ------------------------------------------------------------
384 -------------------SK-D---
385 > 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
386 M--------------------------------------------IAVSGPSYEAFSYG-
387 ---GQAR--------------------------FNNQTV-----------VD--------
388 ------------------------------------KVPPDMLH----------------
389 --LIDANW------------YQ---------YPPLNPMW--------------HGILGFV
390 IGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNFLMMFCM-SPPMVINC-YY-
391 ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIVKGLSG-KPLSINGALIRI
392 IAIWLFSLGW-TIAPMFG-WNRYVP-------EGN----MTACGTDYFN--RGLLSASYL
393 VCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKN----------------------------
394 ------------------------------------------------------------
395 ----------------------------------------------MREQAKK--MNVAS
396 L------------------------RS-S-ENQNTSAECKLAKVALMTISLWFMAWTPYL
397 VINFSGIF--NL-V--KISPLFTIWGSLFAKANAVYNPIVYGISHPKYRAALF-------
398 --AKFP----SLAC-A---AEPSS-DAVST--TSGTTTVT-D------------------
399 ------------------------------------------------------------
400 ---------------NEK-SN-A---
401 > 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
402 M----------------------------------------------ANQLSYSSLGWP-
403 ---YQP-----------------------------NASV-----------VD--------
404 ------------------------------------TMPKEMLY----------------
405 --MIHEHW------------YA---------FPPMNPLW--------------YSILGVA
406 MIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDFCMMAFM-MPTMTSNC-FA-
407 ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIVRGMAA-APLTHKKATLLL
408 LFVWIWSGGW-TILPFFG-WSRYVP-------EGN----LTSCTVDYLT--KDWSSASYV
409 VIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQ----------------------------
410 ------------------------------------------------------------
411 ----------------------------------------------LREQAKK--MNVAS
412 L------------------------RANA-DQQKQSAECRLAKVAMMTVGLWFMAWTPYL
413 IISWAGVF--SSGT--RLTPLATIWGSVFAKANSCYNPIVYGISHPRYKAALY-------
414 --QRFP----SLACGS---GESGS-DVKSE--ASATTTME-E------------------
415 ------------------------------------------------------------
416 ---------------KPKIPE-A---
417 > 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
418 M-----------------------------------------------------------
419 ---VESTTLV------------------NQTWWY-NPTV-----------D---------
420 ------------------------------------------------------------
421 ---IHPHW------------AK---------FDPIPDAV--------------YYSVGIF
422 IGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDLSFSAINGFPLKTISA-FM-
423 KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIGRPMAASKKMSHRRAFLMI
424 IFVWMWSIVW-SVGPVFN-WGAYVP-------EGI----LTSCSFDYLS--TDPSTRSFI
425 LCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKE----------------------------
426 ------------------------------------------------------------
427 ----------------------------------------------MAAMAKR--LNAKE
428 L------------------------RK---AQAGASAEMKLAKISMVIITQFMLSWSPYA
429 IIALLAQF-GPA-E--WVTPYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQ-------
430 --TTFPWLLTCCQFDE---KECED-ANDAE--EEVVASER---GGESRD-AAQMKEMMAM
431 MQKMQAQQAAYQPPPPPQGY--PPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQGAP
432 PQVEAPQGAPPQGVDNQA-YQ-A---
433 > 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
434 M-----------------------------------------------------------
435 ---GRDLR-D------------------NETWWY-NPSI-----------V---------
436 ------------------------------------------------------------
437 ---VHPHW------------RE---------FDQVPDAV--------------YYSLGIF
438 IGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDFTFSLVNGFPLMTISC-FL-
439 KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIGRPMAASKKMSHRRAFIMI
440 IFVWLWSVLW-AIGPIFG-WGAYTL-------EGV----LCNCSFDYIS--RDSTTRSNI
441 LCMFILGFFGPILIIFFCYFNIVMSVSNHEKE----------------------------
442 ------------------------------------------------------------
443 ----------------------------------------------MAAMAKR--LNAKE
444 L------------------------RK---AQAGANAEMRLAKISIVIVSQFLLSWSPYA
445 VVALLAQF-GPL-E--WVTPYAAQLPVMFAKASAIHNPMIYSVSHPKFREAIS-------
446 --QTFPWVLTCCQFDD---KETED-DKDAE--TEIPAGES-SDAAPSAD-AAQMKEMMAM
447 MQKMQQQQAAY----PPQGYAPPPQGYPPQGY--PPQGYPPQGYPPQGYPP---PPQGAP
448 PQ-GAPPAAPPQGVDNQA-YQ-A---
449 > 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
450 MMDVNSSGRPDLY-----------------------------------------------
451 -----------------GHLRSFL--LPEVGR---GLPD--------------------L
452 SPDGGADPVAGSWAPHLLS---EVTA----------------------------------
453 --SPAPTW-----------------------DAPPDNAS--GCGEQINYGRVEKVVIGSI
454 LTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIG-
455 GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
456 LSVWLLSASI-TLPPLFG-WAQNVN--DDK---------VCLISQDF----------GYT
457 IYSTAVAFYIPMSVMLFMYYQIYKAAR---------------------------------
458 -----------------KSAAKHKFPGFPRVEPDSVI----------------------A
459 LNGIVK----------------------LQKEVEECAN--------LSRLLKH-------
460 -------------------------ER-K-NISIFKREQKAATTLGIIVGAFTVCWLPFF
461 LLSTARPFICGT-SCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYR-SLL---
462 ----------QCQYRN-INRKLSA-AGMHE--ALKLAERP-E--------RPEF-----V
463 LQNADY--------CRKKGHD---------------------------------------
464 ----------------------S---
465 > 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
466 M-----------------------------------------------------------
467 ------------------------------------------------------------
468 --------------PHLLSGFLEVTA----------------------------------
469 --SPAPTW-----------------------DAPPDNVS--GCGEQINYGRVEKVVIGSI
470 LTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIG-
471 GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
472 LSVWLLSASI-TLPPLFG-WAQNVN--DDK---------VCLISQDF----------GYT
473 IYSTAVAFYIPMSVMLFMYYQIYKAAR---------------------------------
474 -----------------KSAAKHKFPGFPRVQPESVI----------------------S
475 LNGVVK----------------------LQKEVEECAN--------LSRLLKH-------
476 -------------------------ER-K-NISIFKREQKAATTLGIIVGAFTVCWLPFF
477 LLSTARPFICGT-SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRPTSR-SLL---
478 ----------QCQYRN-INRKLSA-AGMHE--ALKLAERP-E--------RSEF-----V
479 LQNSDH--------CGKKGHD---------------------------------------
480 ----------------------T---
481 > 31=p A47425 serotonin receptor 5HT-7 - rat
482 M-----------------------------------------------------------
483 ------------------------------------------------------------
484 --------------PHLLSGFLEVTA----------------------------------
485 --SPAPTW-----------------------DAPPDNVS--GCGEQINYGRVEKVVIGSI
486 LTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADLSVAVAV-MPFVSVTDLIG-
487 GKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMI
488 LSVWLLSASI-TLPPLFG-WAQNVN--DDK---------VCLISQDF----------GYT
489 IYSTAVAFYIPMSVMLFMYYQIYKAAR---------------------------------
490 -----------------KSAAKHKFPGFPRVQPESVI----------------------S
491 LNGVVK----------------------LQKEVEECAN--------LSRLLKH-------
492 -------------------------ER-K-NISIFKREQKAATTLGIIVGAFTVCWLPFF
493 LLSTARPFICGT-SCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYR-SLL---
494 ----------QCQYRN-INRKLSA-AGMHE--ALKLAERP-E--------RSEF-----V
495 LQNSDH--------CGKKGHD---------------------------------------
496 ----------------------T---
497 > 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
498 M-DVLSPGQ---------------------------------------------------
499 -----------------GNNTTSPPAPFETGG---NTTG--------------------I
500 -------------------------S----------------------------------
501 --DVTVSY---------------------------------------------QVITSLL
502 LGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQ-VL-
503 NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALI
504 SLTWLIGFLI-SIPPMLG-WRTPEDRSDPD---------ACTISKDH----------GYT
505 IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
506 -----------TVKKVEKTGADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGAL-C
507 ANGAVRQGDDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAP-----ASFERK-------
508 ----NERNA----------------EA-K-RKMALARERKTVKTLGIIMGTFILCWLPFF
509 IVALVLPF-CES-SC-HMPTLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KII---
510 ----------KCKFCR--------------------------------------------
511 ------------------------------------------------------------
512 ----------------------Q---
513 > 33=p A35181 serotonin receptor class 1A - rat
514 M-DVFSFGQ---------------------------------------------------
515 -----------------GNNTTASQEPFGTGG---NVTS--------------------I
516 -------------------------S----------------------------------
517 --DVTFSY---------------------------------------------QVITSLL
518 LGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDLMVSVLV-LPMAALYQ-VL-
519 NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAITDPIDYVNKRTPRRAAALI
520 SLTWLIGFLI-SIPPMLG-WRTPEDRSDPD---------ACTISKDH----------GYT
521 IYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK----------------------------
522 -----------TVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDWRRCAENRAVGTP-C
523 TNGAVRQGDDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAP-----ACLERK-------
524 ----NERNA----------------EA-K-RKMALARERKTVKTLGIIMGTFILCWLPFF
525 IVALVLPF-CES-SC-HMPALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFK-KII---
526 ----------KCKFCR--------------------------------------------
527 ------------------------------------------------------------
528 ----------------------R---
529 > 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
530 M-ANFTFGDLALD-----------------------------------------------
531 -------------VARMGGLASTPSGLRSTGL---TTPG--------------------L
532 SPTG------------------LVTS----------------------------------
533 --DFNDSYGLTGQFINGSHSSRSRDNASAN-DTSATNMTDDRYWSLTVYSHEHLVLTSVI
534 LGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSE-IS-
535 KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMI
536 MVVWIVALFI-SIPPLFG-WRDPNN--DPD------KTGTCIISQDK----------GYT
537 IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
538 SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK----------------NRAKKLPEN
539 ANGVNSNSSSSERLKQIQIE-----------TAEAFANGCAEEAS-IAMLERQ-CNNGKK
540 ISSNDTPYS----------------RT-R-EKLELKRERKAARTLAIITGAFLICWLPFF
541 IIALIGPF-VDP-E--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KIL---
542 ----------FGKYRR--------------------------------------------
543 ------------------GH----------------------------------------
544 ----------------------R---
545 > 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
546 M-ANFTFGDLALD-----------------------------------------------
547 -------------VARMGGLASTPSGLRSTGL---TTPG--------------------L
548 SPTG------------------LVTS----------------------------------
549 --DFNDSYGLTGQFINGSHSSRSRDNASAN-DTSATNMTDDRYWSLTVYSHEHLVLTSVI
550 LGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADLMVAVLV-MPLSVVSE-IS-
551 KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVTS-IDYIRRRSARRILLMI
552 MVVWIVALFI-SIPPLFG-WRDPNN--DPD------KTGTCIISQDK----------GYT
553 IFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEETTLVASPKTEYSVV
554 SDCNGCNSPDSTTEKKKRRAPFKSYGCSPRPERKK----------------NRAKKLPEN
555 ANGVNSNSSSSERLKQIQIE-----------TAEAFANGCAEEAS-IAMLERQ-CNNGKK
556 ISSNDTPYS----------------RT-R-EKLELKRERKAARTLAIITGAFLICWLPFF
557 IIALIGPF-VDP-E--GIPPFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQ-KIL---
558 ----------FGKYRR--------------------------------------------
559 ------------------GH----------------------------------------
560 ----------------------R---
561 > 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
562 M-EGAE-GQEELDWEA--------------------------------------------
563 ---------LYLRLP-----------LQNCSW---NSTG--------------------W
564 EPNW------------------NVTV----------------------------------
565 --VPNTTW----------------WQASAPFDTPAALVR--------------AAAKAVV
566 LGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADLLVACLV-MPLGAVYE-VV-
567 QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVTN-IDYIHASTAKRVGMMI
568 ACVWTVSFFV-CIAQLLG-WK------DPDWNQRVSEDLRCVVSQDV----------GYQ
569 IFATASSFYVPVLIILILYWRIYQTARKRIRR----------------------------
570 -----------------RRGATARGGVGPPPVP---------------------------
571 AGGALVAGGGSGGIAAAVVAVIGRP---LPTISETTTTGFTNVSSNNTSPEKQSCANGLE
572 A---DPPTTGYGAVAAAYYPSLVRRKP-K-EAADSKRERKAAKTLAIITGAFVACWLPFF
573 VLAILVPT-CDC-E---VSPVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQ-RLL---
574 ----------CGRRVRRR------------------------------------------
575 -----------------RAP----------------------------------------
576 ----------------------Q---
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